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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for MEF2B

Z-value: 0.44

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Transcription factors associated with MEF2B

Gene Symbol Gene ID Gene Info
MEF2B
ENSG00000213999.11 myocyte enhancer factor 2B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MEF2Bhg19_v2_chr19_-_19302931_19302974-0.433.3e-02Click!

Activity profile of MEF2B motif

Sorted Z-values of MEF2B motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_52445191 2.13 ENST00000243050.1
ENST00000394825.1
ENST00000550763.1
ENST00000394824.2
ENST00000548232.1
ENST00000562373.1
NR4A1
nuclear receptor subfamily 4, group A, member 1
chr2_-_157198860 1.91 ENST00000409572.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr4_+_41362796 1.78 ENST00000508501.1
ENST00000512946.1
ENST00000313860.7
ENST00000512632.1
ENST00000512820.1
LIMCH1
LIM and calponin homology domains 1
chr3_+_8543393 1.45 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
LMCD1
LIM and cysteine-rich domains 1
chr5_-_111091948 1.37 ENST00000447165.2
NREP
neuronal regeneration related protein
chr3_+_8543561 1.15 ENST00000397386.3
LMCD1
LIM and cysteine-rich domains 1
chr1_+_84630645 0.99 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr7_+_30951461 0.87 ENST00000311813.4
AQP1
aquaporin 1 (Colton blood group)
chr3_+_8543533 0.82 ENST00000454244.1
LMCD1
LIM and cysteine-rich domains 1
chr11_+_7597639 0.73 ENST00000533792.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr1_+_90098606 0.70 ENST00000370454.4
LRRC8C
leucine rich repeat containing 8 family, member C
chr1_+_145524891 0.69 ENST00000369304.3
ITGA10
integrin, alpha 10
chr1_-_59249732 0.68 ENST00000371222.2
JUN
jun proto-oncogene
chr12_+_44229846 0.67 ENST00000551577.1
ENST00000266534.3
TMEM117
transmembrane protein 117
chr7_-_15726296 0.61 ENST00000262041.5
MEOX2
mesenchyme homeobox 2
chr22_-_51016846 0.58 ENST00000312108.7
ENST00000395650.2
CPT1B
carnitine palmitoyltransferase 1B (muscle)
chr15_-_52970820 0.57 ENST00000261844.7
ENST00000399202.4
ENST00000562135.1
FAM214A
family with sequence similarity 214, member A
chr22_-_51017084 0.52 ENST00000360719.2
ENST00000457250.1
ENST00000440709.1
CPT1B
carnitine palmitoyltransferase 1B (muscle)
chr2_-_165424973 0.40 ENST00000543549.1
GRB14
growth factor receptor-bound protein 14
chr14_-_22005343 0.39 ENST00000327430.3
SALL2
spalt-like transcription factor 2
chr10_-_3827371 0.37 ENST00000469435.1
KLF6
Kruppel-like factor 6
chr20_+_11898507 0.36 ENST00000378226.2
BTBD3
BTB (POZ) domain containing 3
chr11_-_18034701 0.35 ENST00000265965.5
SERGEF
secretion regulating guanine nucleotide exchange factor
chr4_-_25865159 0.34 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr4_-_143226979 0.33 ENST00000514525.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr5_-_42812143 0.31 ENST00000514985.1
SEPP1
selenoprotein P, plasma, 1
chr7_+_75931861 0.29 ENST00000248553.6
HSPB1
heat shock 27kDa protein 1
chr2_+_33661382 0.28 ENST00000402538.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr11_-_47400062 0.28 ENST00000533030.1
SPI1
spleen focus forming virus (SFFV) proviral integration oncogene
chr12_+_25205446 0.27 ENST00000557489.1
ENST00000354454.3
ENST00000536173.1
LRMP
lymphoid-restricted membrane protein
chr7_-_105332084 0.26 ENST00000472195.1
ATXN7L1
ataxin 7-like 1
chr16_-_31439735 0.26 ENST00000287490.4
COX6A2
cytochrome c oxidase subunit VIa polypeptide 2
chr17_+_42248063 0.25 ENST00000293414.1
ASB16
ankyrin repeat and SOCS box containing 16
chr1_+_84630367 0.25 ENST00000370680.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr12_+_15699286 0.23 ENST00000442921.2
ENST00000542557.1
ENST00000445537.2
ENST00000544244.1
PTPRO
protein tyrosine phosphatase, receptor type, O
chr8_+_1993152 0.23 ENST00000262113.4
MYOM2
myomesin 2
chr1_-_116311402 0.22 ENST00000261448.5
CASQ2
calsequestrin 2 (cardiac muscle)
chr12_-_371994 0.22 ENST00000343164.4
ENST00000436453.1
ENST00000445055.2
ENST00000546319.1
SLC6A13
solute carrier family 6 (neurotransmitter transporter), member 13
chr6_+_139094657 0.21 ENST00000332797.6
CCDC28A
coiled-coil domain containing 28A
chr11_-_47399942 0.21 ENST00000227163.4
SPI1
spleen focus forming virus (SFFV) proviral integration oncogene
chr10_-_3827417 0.21 ENST00000497571.1
ENST00000542957.1
KLF6
Kruppel-like factor 6
chr19_+_56713670 0.21 ENST00000534327.1
ZSCAN5C
zinc finger and SCAN domain containing 5C
chr8_+_107282368 0.21 ENST00000521369.2
RP11-395G23.3
RP11-395G23.3
chr3_+_159570722 0.21 ENST00000482804.1
SCHIP1
schwannomin interacting protein 1
chr3_+_179370517 0.20 ENST00000263966.3
USP13
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr11_-_47400078 0.20 ENST00000378538.3
SPI1
spleen focus forming virus (SFFV) proviral integration oncogene
chr5_-_66492562 0.20 ENST00000256447.4
CD180
CD180 molecule
chr19_-_49926698 0.19 ENST00000270631.1
PTH2
parathyroid hormone 2
chr7_+_86781847 0.19 ENST00000432366.2
ENST00000423590.2
ENST00000394703.5
DMTF1
cyclin D binding myb-like transcription factor 1
chr4_-_143227088 0.19 ENST00000511838.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr17_-_34417479 0.19 ENST00000225245.5
CCL3
chemokine (C-C motif) ligand 3
chr20_+_10199468 0.18 ENST00000254976.2
ENST00000304886.2
SNAP25
synaptosomal-associated protein, 25kDa
chr8_+_1993173 0.18 ENST00000523438.1
MYOM2
myomesin 2
chr6_+_42984723 0.17 ENST00000332245.8
KLHDC3
kelch domain containing 3
chr3_+_54157480 0.16 ENST00000490478.1
CACNA2D3
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr6_-_33160231 0.15 ENST00000395194.1
ENST00000457788.1
ENST00000341947.2
ENST00000357486.1
ENST00000374714.1
ENST00000374713.1
ENST00000395197.1
ENST00000374712.1
ENST00000361917.1
ENST00000374708.4
COL11A2
collagen, type XI, alpha 2
chr12_+_25205568 0.14 ENST00000548766.1
ENST00000556887.1
LRMP
lymphoid-restricted membrane protein
chr7_-_37488834 0.14 ENST00000310758.4
ELMO1
engulfment and cell motility 1
chr21_-_33984456 0.12 ENST00000431216.1
ENST00000553001.1
ENST00000440966.1
AP000275.65
C21orf59
Uncharacterized protein
chromosome 21 open reading frame 59
chr5_+_53751445 0.12 ENST00000302005.1
HSPB3
heat shock 27kDa protein 3
chr6_+_44194762 0.12 ENST00000371708.1
SLC29A1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr1_+_26348259 0.12 ENST00000374280.3
EXTL1
exostosin-like glycosyltransferase 1
chr8_+_11351494 0.11 ENST00000259089.4
BLK
B lymphoid tyrosine kinase
chr2_+_233497931 0.11 ENST00000264059.3
EFHD1
EF-hand domain family, member D1
chr15_+_40531621 0.11 ENST00000560346.1
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chrX_+_70521584 0.11 ENST00000373829.3
ENST00000538820.1
ITGB1BP2
integrin beta 1 binding protein (melusin) 2
chr5_-_42811986 0.10 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
SEPP1
selenoprotein P, plasma, 1
chr5_-_131347501 0.10 ENST00000543479.1
ACSL6
acyl-CoA synthetase long-chain family member 6
chr8_+_11351876 0.10 ENST00000529894.1
BLK
B lymphoid tyrosine kinase
chr9_+_116327326 0.10 ENST00000342620.5
RGS3
regulator of G-protein signaling 3
chr3_+_46924829 0.10 ENST00000313049.5
PTH1R
parathyroid hormone 1 receptor
chr10_-_96829246 0.10 ENST00000371270.3
ENST00000535898.1
ENST00000539050.1
CYP2C8
cytochrome P450, family 2, subfamily C, polypeptide 8
chr1_+_22778337 0.10 ENST00000404138.1
ENST00000400239.2
ENST00000375647.4
ENST00000374651.4
ZBTB40
zinc finger and BTB domain containing 40
chr17_-_42200996 0.09 ENST00000587135.1
ENST00000225983.6
ENST00000393622.2
ENST00000588703.1
HDAC5
histone deacetylase 5
chr1_+_92632542 0.09 ENST00000409154.4
ENST00000370378.4
KIAA1107
KIAA1107
chr1_-_156460391 0.09 ENST00000360595.3
MEF2D
myocyte enhancer factor 2D
chr7_+_18535893 0.09 ENST00000432645.2
ENST00000441542.2
HDAC9
histone deacetylase 9
chr19_+_16607122 0.09 ENST00000221671.3
ENST00000594035.1
ENST00000599550.1
ENST00000594813.1
C19orf44
chromosome 19 open reading frame 44
chr1_+_167063282 0.09 ENST00000361200.2
DUSP27
dual specificity phosphatase 27 (putative)
chr15_+_40531243 0.08 ENST00000558055.1
ENST00000455577.2
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr17_-_42200958 0.08 ENST00000336057.5
HDAC5
histone deacetylase 5
chr20_-_62582475 0.08 ENST00000369908.5
UCKL1
uridine-cytidine kinase 1-like 1
chr6_+_152128371 0.08 ENST00000443427.1
ESR1
estrogen receptor 1
chr1_-_19229014 0.08 ENST00000538839.1
ENST00000290597.5
ALDH4A1
aldehyde dehydrogenase 4 family, member A1
chr17_+_7184986 0.07 ENST00000317370.8
ENST00000571308.1
SLC2A4
solute carrier family 2 (facilitated glucose transporter), member 4
chr9_-_74980113 0.07 ENST00000376962.5
ENST00000376960.4
ENST00000237937.3
ZFAND5
zinc finger, AN1-type domain 5
chr16_+_12059050 0.07 ENST00000396495.3
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr19_-_40324255 0.07 ENST00000593685.1
ENST00000600611.1
DYRK1B
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr12_+_25205666 0.06 ENST00000547044.1
LRMP
lymphoid-restricted membrane protein
chr1_+_160051319 0.06 ENST00000368088.3
KCNJ9
potassium inwardly-rectifying channel, subfamily J, member 9
chr3_+_127634069 0.06 ENST00000405109.1
KBTBD12
kelch repeat and BTB (POZ) domain containing 12
chr1_+_74701062 0.06 ENST00000326637.3
TNNI3K
TNNI3 interacting kinase
chr16_+_12058961 0.06 ENST00000053243.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr15_+_40226304 0.05 ENST00000559624.1
ENST00000382727.2
ENST00000263791.5
ENST00000560648.1
EIF2AK4
eukaryotic translation initiation factor 2 alpha kinase 4
chr18_+_3252265 0.05 ENST00000580887.1
ENST00000536605.1
MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr13_+_39261224 0.04 ENST00000280481.7
FREM2
FRAS1 related extracellular matrix protein 2
chr8_+_95565947 0.04 ENST00000523011.1
RP11-267M23.4
RP11-267M23.4
chr5_-_16509101 0.04 ENST00000399793.2
FAM134B
family with sequence similarity 134, member B
chr6_+_152128686 0.04 ENST00000206249.3
ESR1
estrogen receptor 1
chr8_-_62602327 0.04 ENST00000445642.3
ENST00000517847.2
ENST00000389204.4
ENST00000517661.1
ENST00000517903.1
ENST00000522603.1
ENST00000522349.1
ENST00000522835.1
ENST00000541428.1
ENST00000518306.1
ASPH
aspartate beta-hydroxylase
chr19_-_40324767 0.04 ENST00000601972.1
ENST00000430012.2
ENST00000323039.5
ENST00000348817.3
DYRK1B
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr14_+_56046914 0.04 ENST00000413890.2
ENST00000395309.3
ENST00000554567.1
ENST00000555498.1
KTN1
kinectin 1 (kinesin receptor)
chr14_+_56046990 0.04 ENST00000438792.2
ENST00000395314.3
ENST00000395308.1
KTN1
kinectin 1 (kinesin receptor)
chr11_-_88796803 0.04 ENST00000418177.2
ENST00000455756.2
GRM5
glutamate receptor, metabotropic 5
chr1_-_201391149 0.03 ENST00000555948.1
ENST00000556362.1
TNNI1
troponin I type 1 (skeletal, slow)
chr16_+_31225337 0.03 ENST00000322122.3
TRIM72
tripartite motif containing 72
chr10_-_75415825 0.03 ENST00000394810.2
SYNPO2L
synaptopodin 2-like
chr19_-_16008880 0.03 ENST00000011989.7
ENST00000221700.6
CYP4F2
cytochrome P450, family 4, subfamily F, polypeptide 2
chr1_-_206945830 0.03 ENST00000423557.1
IL10
interleukin 10
chr12_-_7899935 0.03 ENST00000543765.1
CLEC4C
C-type lectin domain family 4, member C
chr8_-_95565673 0.02 ENST00000437199.1
ENST00000297591.5
ENST00000421249.2
KIAA1429
KIAA1429
chr7_+_143013198 0.02 ENST00000343257.2
CLCN1
chloride channel, voltage-sensitive 1
chr6_+_12007963 0.02 ENST00000607445.1
RP11-456H18.2
RP11-456H18.2
chr5_+_138609782 0.01 ENST00000361059.2
ENST00000514694.1
ENST00000504203.1
ENST00000502929.1
ENST00000394800.2
ENST00000509644.1
ENST00000505016.1
MATR3
matrin 3
chr7_+_120629653 0.01 ENST00000450913.2
ENST00000340646.5
CPED1
cadherin-like and PC-esterase domain containing 1
chr11_-_104480019 0.01 ENST00000536529.1
ENST00000545630.1
ENST00000538641.1
RP11-886D15.1
RP11-886D15.1
chr14_+_76776957 0.01 ENST00000512784.1
ESRRB
estrogen-related receptor beta
chr11_+_75110530 0.01 ENST00000531188.1
ENST00000530164.1
ENST00000422465.2
ENST00000278572.6
ENST00000534440.1
ENST00000527446.1
ENST00000526608.1
ENST00000527273.1
ENST00000524851.1
RPS3
ribosomal protein S3
chr12_+_119616447 0.01 ENST00000281938.2
HSPB8
heat shock 22kDa protein 8
chr4_+_44680429 0.01 ENST00000281543.5
GUF1
GUF1 GTPase homolog (S. cerevisiae)
chr2_-_86564776 0.01 ENST00000165698.5
ENST00000541910.1
ENST00000535845.1
REEP1
receptor accessory protein 1
chr5_-_131347583 0.01 ENST00000379255.1
ENST00000430403.1
ENST00000544770.1
ENST00000379246.1
ENST00000414078.1
ENST00000441995.1
ACSL6
acyl-CoA synthetase long-chain family member 6
chr3_+_138067521 0.00 ENST00000494949.1
MRAS
muscle RAS oncogene homolog
chr8_-_7309887 0.00 ENST00000458665.1
ENST00000528168.1
SPAG11B
sperm associated antigen 11B
chr6_+_123038689 0.00 ENST00000354275.2
ENST00000368446.1
PKIB
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr1_-_27240455 0.00 ENST00000254227.3
NR0B2
nuclear receptor subfamily 0, group B, member 2

Network of associatons between targets according to the STRING database.

First level regulatory network of MEF2B

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.3 2.1 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.3 0.9 GO:0035378 carbon dioxide transmembrane transport(GO:0035378) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.2 1.2 GO:0097338 response to clozapine(GO:0097338)
0.2 0.7 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.2 0.7 GO:0035026 leading edge cell differentiation(GO:0035026)
0.1 3.4 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 0.6 GO:0001757 somite specification(GO:0001757)
0.1 0.2 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 0.3 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.1 0.2 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.1 0.2 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.1 1.1 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.2 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.2 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.2 GO:0086068 Purkinje myocyte to ventricular cardiac muscle cell signaling(GO:0086029) Purkinje myocyte to ventricular cardiac muscle cell communication(GO:0086068)
0.0 0.1 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.0 0.1 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.0 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.2 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.1 GO:0060523 prostate epithelial cord elongation(GO:0060523) epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.0 0.0 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.0 0.1 GO:0044211 CTP salvage(GO:0044211)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0020003 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.2 0.7 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.1 0.7 GO:0035976 AP1 complex(GO:0035976)
0.1 1.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.2 1.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.1 0.7 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.5 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.1 0.3 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.1 1.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.2 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 1.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.7 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.3 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.7 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.2 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.2 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.7 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 2.2 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.1 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.1 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.0 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.6 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.0 GO:0097258 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.7 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.2 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.7 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 1.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.6 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 4.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.7 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 1.1 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling