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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for MESP1

Z-value: 0.87

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Transcription factors associated with MESP1

Gene Symbol Gene ID Gene Info
MESP1
ENSG00000166823.5 mesoderm posterior bHLH transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MESP1hg19_v2_chr15_-_90294523_902945410.135.5e-01Click!

Activity profile of MESP1 motif

Sorted Z-values of MESP1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_39382900 9.59 ENST00000377721.3
ENST00000455970.2
KRTAP9-2
keratin associated protein 9-2
chr17_+_39394250 4.21 ENST00000254072.6
KRTAP9-8
keratin associated protein 9-8
chr10_+_94608218 2.69 ENST00000371543.1
EXOC6
exocyst complex component 6
chr2_+_241631262 1.48 ENST00000337801.4
ENST00000429564.1
AQP12A
aquaporin 12A
chr2_-_241622278 1.45 ENST00000407834.3
AQP12B
aquaporin 12B
chr14_+_75746340 1.33 ENST00000555686.1
ENST00000555672.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr2_-_157189180 1.33 ENST00000539077.1
ENST00000424077.1
ENST00000426264.1
ENST00000339562.4
ENST00000421709.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr4_+_156588806 1.27 ENST00000513574.1
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr14_+_75746781 1.20 ENST00000555347.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr8_-_93029865 1.19 ENST00000422361.2
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr20_-_39317868 1.17 ENST00000373313.2
MAFB
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
chr1_-_209979465 1.15 ENST00000542854.1
IRF6
interferon regulatory factor 6
chr13_+_31480328 1.10 ENST00000380482.4
MEDAG
mesenteric estrogen-dependent adipogenesis
chr8_+_120220561 1.09 ENST00000276681.6
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr3_-_49459865 1.08 ENST00000427987.1
AMT
aminomethyltransferase
chr3_-_49459878 1.06 ENST00000546031.1
ENST00000458307.2
ENST00000430521.1
AMT
aminomethyltransferase
chr12_-_42877726 1.06 ENST00000548696.1
PRICKLE1
prickle homolog 1 (Drosophila)
chr10_-_93392811 1.05 ENST00000238994.5
PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr12_-_42877764 1.04 ENST00000455697.1
PRICKLE1
prickle homolog 1 (Drosophila)
chr11_-_33913708 0.93 ENST00000257818.2
LMO2
LIM domain only 2 (rhombotin-like 1)
chr1_-_209979375 0.91 ENST00000367021.3
IRF6
interferon regulatory factor 6
chr3_+_43328004 0.90 ENST00000454177.1
ENST00000429705.2
ENST00000296088.7
ENST00000437827.1
SNRK
SNF related kinase
chr19_+_48673949 0.90 ENST00000328759.7
C19orf68
chromosome 19 open reading frame 68
chr6_+_18387570 0.89 ENST00000259939.3
RNF144B
ring finger protein 144B
chr1_+_61542922 0.88 ENST00000407417.3
NFIA
nuclear factor I/A
chr1_+_26438289 0.87 ENST00000374271.4
ENST00000374269.1
PDIK1L
PDLIM1 interacting kinase 1 like
chr3_-_128294929 0.87 ENST00000356020.2
C3orf27
chromosome 3 open reading frame 27
chr4_+_156588350 0.87 ENST00000296518.7
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr7_+_12727250 0.85 ENST00000404894.1
ARL4A
ADP-ribosylation factor-like 4A
chr4_+_156588249 0.84 ENST00000393832.3
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr2_+_219745020 0.83 ENST00000258411.3
WNT10A
wingless-type MMTV integration site family, member 10A
chr20_-_23030296 0.83 ENST00000377103.2
THBD
thrombomodulin
chr4_+_156588115 0.83 ENST00000455639.2
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr12_+_32655048 0.82 ENST00000427716.2
ENST00000266482.3
FGD4
FYVE, RhoGEF and PH domain containing 4
chr5_+_68788594 0.82 ENST00000396442.2
ENST00000380766.2
OCLN
occludin
chr1_-_45672221 0.82 ENST00000359600.5
ZSWIM5
zinc finger, SWIM-type containing 5
chr17_+_73521763 0.82 ENST00000167462.5
ENST00000375227.4
ENST00000392550.3
ENST00000578363.1
ENST00000579392.1
LLGL2
lethal giant larvae homolog 2 (Drosophila)
chr5_-_137071756 0.81 ENST00000394937.3
ENST00000309755.4
KLHL3
kelch-like family member 3
chr4_+_156587979 0.81 ENST00000511507.1
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr7_+_22766766 0.78 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
IL6
interleukin 6 (interferon, beta 2)
chr8_-_30891078 0.78 ENST00000339382.2
ENST00000475541.1
PURG
purine-rich element binding protein G
chr6_-_130031358 0.77 ENST00000368149.2
ARHGAP18
Rho GTPase activating protein 18
chr12_-_95044309 0.77 ENST00000261226.4
TMCC3
transmembrane and coiled-coil domain family 3
chr10_+_94608245 0.76 ENST00000443748.2
ENST00000260762.6
EXOC6
exocyst complex component 6
chr8_-_127570603 0.76 ENST00000304916.3
FAM84B
family with sequence similarity 84, member B
chr8_-_103668114 0.72 ENST00000285407.6
KLF10
Kruppel-like factor 10
chr20_+_42574317 0.71 ENST00000358131.5
TOX2
TOX high mobility group box family member 2
chr13_-_52980263 0.70 ENST00000258613.4
ENST00000544466.1
THSD1
thrombospondin, type I, domain containing 1
chr11_+_68080077 0.70 ENST00000294304.7
LRP5
low density lipoprotein receptor-related protein 5
chr2_-_238499303 0.70 ENST00000409576.1
RAB17
RAB17, member RAS oncogene family
chr12_-_96184533 0.69 ENST00000343702.4
ENST00000344911.4
NTN4
netrin 4
chr13_-_77460525 0.68 ENST00000377474.2
ENST00000317765.2
KCTD12
potassium channel tetramerization domain containing 12
chr5_+_68710906 0.67 ENST00000325631.5
ENST00000454295.2
MARVELD2
MARVEL domain containing 2
chr10_-_33625154 0.66 ENST00000265371.4
NRP1
neuropilin 1
chr3_+_32280159 0.66 ENST00000458535.2
ENST00000307526.3
CMTM8
CKLF-like MARVEL transmembrane domain containing 8
chr15_+_75639296 0.65 ENST00000564500.1
ENST00000355059.4
ENST00000566752.1
NEIL1
nei endonuclease VIII-like 1 (E. coli)
chr1_+_6615241 0.64 ENST00000333172.6
ENST00000328191.4
ENST00000351136.3
TAS1R1
taste receptor, type 1, member 1
chr16_+_4845379 0.63 ENST00000588606.1
ENST00000586005.1
SMIM22
small integral membrane protein 22
chr15_+_75640068 0.62 ENST00000565051.1
ENST00000564257.1
ENST00000567005.1
NEIL1
nei endonuclease VIII-like 1 (E. coli)
chr16_-_89268070 0.62 ENST00000562855.2
SLC22A31
solute carrier family 22, member 31
chr2_-_75788038 0.62 ENST00000393913.3
ENST00000410113.1
EVA1A
eva-1 homolog A (C. elegans)
chr19_+_54058073 0.59 ENST00000505949.1
ENST00000513265.1
ZNF331
zinc finger protein 331
chr1_-_33647267 0.58 ENST00000291416.5
TRIM62
tripartite motif containing 62
chr11_-_118122996 0.57 ENST00000525386.1
ENST00000527472.1
ENST00000278949.4
MPZL3
myelin protein zero-like 3
chr19_+_6464502 0.56 ENST00000308243.7
CRB3
crumbs homolog 3 (Drosophila)
chr5_+_78532003 0.56 ENST00000396137.4
JMY
junction mediating and regulatory protein, p53 cofactor
chr9_+_71986182 0.54 ENST00000303068.7
FAM189A2
family with sequence similarity 189, member A2
chr4_+_41540160 0.54 ENST00000503057.1
ENST00000511496.1
LIMCH1
LIM and calponin homology domains 1
chr9_-_126030817 0.52 ENST00000348403.5
ENST00000447404.2
ENST00000360998.3
STRBP
spermatid perinuclear RNA binding protein
chr6_-_30712313 0.52 ENST00000376377.2
ENST00000259874.5
IER3
immediate early response 3
chr2_-_165477971 0.52 ENST00000446413.2
GRB14
growth factor receptor-bound protein 14
chr15_+_75639951 0.52 ENST00000564784.1
ENST00000569035.1
NEIL1
nei endonuclease VIII-like 1 (E. coli)
chr1_+_178694300 0.51 ENST00000367635.3
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr7_+_30960915 0.50 ENST00000441328.2
ENST00000409899.1
ENST00000409611.1
AQP1
aquaporin 1 (Colton blood group)
chrX_+_118108601 0.50 ENST00000371628.3
LONRF3
LON peptidase N-terminal domain and ring finger 3
chr10_-_103347883 0.50 ENST00000339310.3
ENST00000370158.3
ENST00000299206.4
ENST00000456836.2
ENST00000413344.1
ENST00000429502.1
ENST00000430045.1
ENST00000370172.1
ENST00000436284.2
ENST00000370162.3
POLL
polymerase (DNA directed), lambda
chr7_+_16793160 0.49 ENST00000262067.4
TSPAN13
tetraspanin 13
chr3_+_57094469 0.48 ENST00000334325.1
SPATA12
spermatogenesis associated 12
chr2_+_203499901 0.48 ENST00000303116.6
ENST00000392238.2
FAM117B
family with sequence similarity 117, member B
chr17_+_4981535 0.48 ENST00000318833.3
ZFP3
ZFP3 zinc finger protein
chr17_-_21156578 0.47 ENST00000399011.2
ENST00000468196.1
C17orf103
chromosome 17 open reading frame 103
chr7_+_12726474 0.47 ENST00000396662.1
ENST00000356797.3
ENST00000396664.2
ARL4A
ADP-ribosylation factor-like 4A
chr19_+_7660716 0.47 ENST00000160298.4
ENST00000446248.2
CAMSAP3
calmodulin regulated spectrin-associated protein family, member 3
chr16_+_3162557 0.46 ENST00000382192.3
ENST00000219091.4
ENST00000444510.2
ENST00000414351.1
ZNF205
zinc finger protein 205
chr19_+_42381337 0.46 ENST00000597454.1
ENST00000444740.2
CD79A
CD79a molecule, immunoglobulin-associated alpha
chrX_+_118108571 0.46 ENST00000304778.7
LONRF3
LON peptidase N-terminal domain and ring finger 3
chr4_+_75310851 0.46 ENST00000395748.3
ENST00000264487.2
AREG
amphiregulin
chr9_-_116061476 0.45 ENST00000441031.3
RNF183
ring finger protein 183
chr13_+_112721913 0.45 ENST00000330949.1
SOX1
SRY (sex determining region Y)-box 1
chr7_-_38670957 0.45 ENST00000325590.5
ENST00000428293.2
AMPH
amphiphysin
chr1_+_78354175 0.44 ENST00000401035.3
ENST00000457030.1
ENST00000330010.8
NEXN
nexilin (F actin binding protein)
chr12_-_48398104 0.44 ENST00000337299.6
ENST00000380518.3
COL2A1
collagen, type II, alpha 1
chr4_-_186733363 0.44 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
SORBS2
sorbin and SH3 domain containing 2
chr16_-_28374829 0.43 ENST00000532254.1
NPIPB6
nuclear pore complex interacting protein family, member B6
chrX_-_63005405 0.43 ENST00000374878.1
ENST00000437457.2
ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr13_+_113633620 0.43 ENST00000421756.1
ENST00000375601.3
MCF2L
MCF.2 cell line derived transforming sequence-like
chr16_+_83932684 0.42 ENST00000262430.4
MLYCD
malonyl-CoA decarboxylase
chr6_-_41888843 0.42 ENST00000434077.1
ENST00000409312.1
MED20
mediator complex subunit 20
chr17_-_34502410 0.42 ENST00000398801.3
TBC1D3B
TBC1 domain family, member 3B
chr9_+_90112117 0.42 ENST00000358077.5
DAPK1
death-associated protein kinase 1
chr14_-_106539557 0.42 ENST00000390599.2
IGHV1-8
immunoglobulin heavy variable 1-8
chr19_-_51920835 0.42 ENST00000442846.3
ENST00000530476.1
SIGLEC10
sialic acid binding Ig-like lectin 10
chr3_-_112356944 0.42 ENST00000461431.1
CCDC80
coiled-coil domain containing 80
chr12_+_48357401 0.42 ENST00000429772.2
ENST00000449758.2
TMEM106C
transmembrane protein 106C
chr16_+_14165160 0.41 ENST00000574998.1
ENST00000571589.1
ENST00000574045.1
MKL2
MKL/myocardin-like 2
chr1_+_66999268 0.41 ENST00000371039.1
ENST00000424320.1
SGIP1
SH3-domain GRB2-like (endophilin) interacting protein 1
chr2_+_177053307 0.41 ENST00000331462.4
HOXD1
homeobox D1
chr17_-_8534031 0.41 ENST00000411957.1
ENST00000396239.1
ENST00000379980.4
MYH10
myosin, heavy chain 10, non-muscle
chr19_-_11308190 0.40 ENST00000586659.1
ENST00000592903.1
ENST00000589359.1
ENST00000588724.1
ENST00000432929.2
KANK2
KN motif and ankyrin repeat domains 2
chr7_-_8302298 0.40 ENST00000446305.1
ICA1
islet cell autoantigen 1, 69kDa
chrX_-_107019181 0.40 ENST00000315660.4
ENST00000372384.2
ENST00000502650.1
ENST00000506724.1
TSC22D3
TSC22 domain family, member 3
chr9_+_17579084 0.40 ENST00000380607.4
SH3GL2
SH3-domain GRB2-like 2
chr17_-_8534067 0.40 ENST00000360416.3
ENST00000269243.4
MYH10
myosin, heavy chain 10, non-muscle
chr2_-_106054952 0.39 ENST00000336660.5
ENST00000393352.3
ENST00000607522.1
FHL2
four and a half LIM domains 2
chr3_-_197282821 0.39 ENST00000445160.2
ENST00000446746.1
ENST00000432819.1
ENST00000392379.1
ENST00000441275.1
ENST00000392378.2
BDH1
3-hydroxybutyrate dehydrogenase, type 1
chr7_-_21985656 0.39 ENST00000406877.3
CDCA7L
cell division cycle associated 7-like
chr11_-_1629693 0.39 ENST00000399685.1
KRTAP5-3
keratin associated protein 5-3
chr4_-_21950356 0.38 ENST00000447367.2
ENST00000382152.2
KCNIP4
Kv channel interacting protein 4
chr14_-_106471723 0.38 ENST00000390595.2
IGHV1-3
immunoglobulin heavy variable 1-3
chr10_-_49459800 0.38 ENST00000305531.3
FRMPD2
FERM and PDZ domain containing 2
chr13_-_52027134 0.38 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6
integrator complex subunit 6
chr15_-_22473353 0.38 ENST00000557788.2
IGHV4OR15-8
immunoglobulin heavy variable 4/OR15-8 (non-functional)
chr4_-_2420357 0.38 ENST00000511071.1
ENST00000509171.1
ENST00000290974.2
ZFYVE28
zinc finger, FYVE domain containing 28
chr19_-_51920952 0.38 ENST00000356298.5
ENST00000339313.5
ENST00000529627.1
ENST00000439889.2
ENST00000353836.5
ENST00000432469.2
SIGLEC10
sialic acid binding Ig-like lectin 10
chr7_-_120497178 0.38 ENST00000441017.1
ENST00000424710.1
ENST00000433758.1
TSPAN12
tetraspanin 12
chr6_-_32077078 0.37 ENST00000479795.1
TNXB
tenascin XB
chr1_+_78354297 0.37 ENST00000334785.7
NEXN
nexilin (F actin binding protein)
chr22_-_51016433 0.37 ENST00000405237.3
CPT1B
carnitine palmitoyltransferase 1B (muscle)
chr19_-_46272106 0.37 ENST00000560168.1
SIX5
SIX homeobox 5
chr4_+_166248775 0.37 ENST00000261507.6
ENST00000507013.1
ENST00000393766.2
ENST00000504317.1
MSMO1
methylsterol monooxygenase 1
chr15_+_27112948 0.36 ENST00000555060.1
GABRA5
gamma-aminobutyric acid (GABA) A receptor, alpha 5
chr3_-_134093275 0.36 ENST00000513145.1
ENST00000422605.2
AMOTL2
angiomotin like 2
chr9_-_131940526 0.36 ENST00000372491.2
IER5L
immediate early response 5-like
chr15_-_31283618 0.36 ENST00000563714.1
MTMR10
myotubularin related protein 10
chr12_+_48357340 0.36 ENST00000256686.6
ENST00000549288.1
ENST00000552561.1
ENST00000546749.1
ENST00000552546.1
ENST00000550552.1
TMEM106C
transmembrane protein 106C
chr20_+_48599506 0.36 ENST00000244050.2
SNAI1
snail family zinc finger 1
chr11_-_124632179 0.35 ENST00000278927.5
ENST00000442070.2
ENST00000444566.1
ENST00000435477.1
ESAM
endothelial cell adhesion molecule
chr6_+_159290917 0.35 ENST00000367072.1
C6orf99
chromosome 6 open reading frame 99
chr19_-_51920873 0.35 ENST00000441969.3
ENST00000525998.1
ENST00000436984.2
SIGLEC10
sialic acid binding Ig-like lectin 10
chrX_+_56259316 0.35 ENST00000468660.1
KLF8
Kruppel-like factor 8
chr15_+_83776324 0.35 ENST00000379390.6
ENST00000379386.4
ENST00000565774.1
ENST00000565982.1
TM6SF1
transmembrane 6 superfamily member 1
chr4_+_40198527 0.35 ENST00000381799.5
RHOH
ras homolog family member H
chr16_-_21868978 0.35 ENST00000357370.5
ENST00000451409.1
ENST00000341400.7
ENST00000518761.4
NPIPB4
nuclear pore complex interacting protein family, member B4
chr16_-_29415350 0.35 ENST00000524087.1
NPIPB11
nuclear pore complex interacting protein family, member B11
chr15_+_42131011 0.35 ENST00000458483.1
PLA2G4B
phospholipase A2, group IVB (cytosolic)
chr12_-_49488573 0.34 ENST00000266991.2
DHH
desert hedgehog
chr17_+_37894179 0.34 ENST00000577695.1
ENST00000309156.4
ENST00000309185.3
GRB7
growth factor receptor-bound protein 7
chr10_-_21463116 0.34 ENST00000417816.2
NEBL
nebulette
chr10_-_75457554 0.34 ENST00000374094.4
ENST00000443782.2
AGAP5
ArfGAP with GTPase domain, ankyrin repeat and PH domain 5
chr16_-_21436459 0.34 ENST00000448012.2
ENST00000504841.2
ENST00000419180.2
NPIPB3
nuclear pore complex interacting protein family, member B3
chr17_-_27503770 0.34 ENST00000533112.1
MYO18A
myosin XVIIIA
chr1_-_59043166 0.34 ENST00000371225.2
TACSTD2
tumor-associated calcium signal transducer 2
chr4_+_88928777 0.33 ENST00000237596.2
PKD2
polycystic kidney disease 2 (autosomal dominant)
chr8_+_98881268 0.33 ENST00000254898.5
ENST00000524308.1
ENST00000522025.2
MATN2
matrilin 2
chr7_+_44663908 0.33 ENST00000543843.1
OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr3_-_49851313 0.33 ENST00000333486.3
UBA7
ubiquitin-like modifier activating enzyme 7
chr17_+_37793318 0.32 ENST00000336308.5
STARD3
StAR-related lipid transfer (START) domain containing 3
chr14_-_74416829 0.32 ENST00000534936.1
FAM161B
family with sequence similarity 161, member B
chr15_-_20170354 0.32 ENST00000338912.5
IGHV1OR15-9
immunoglobulin heavy variable 1/OR15-9 (non-functional)
chrX_-_34150428 0.32 ENST00000346193.3
FAM47A
family with sequence similarity 47, member A
chr4_+_75311019 0.32 ENST00000502307.1
AREG
amphiregulin
chr12_+_56661461 0.32 ENST00000546544.1
ENST00000553234.1
COQ10A
coenzyme Q10 homolog A (S. cerevisiae)
chr17_-_39334460 0.32 ENST00000377726.2
KRTAP4-2
keratin associated protein 4-2
chr2_-_50574856 0.32 ENST00000342183.5
NRXN1
neurexin 1
chr12_+_125549973 0.31 ENST00000536752.1
ENST00000261686.6
AACS
acetoacetyl-CoA synthetase
chr8_-_144655141 0.31 ENST00000398882.3
MROH6
maestro heat-like repeat family member 6
chr16_+_6533729 0.31 ENST00000551752.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr14_+_77228532 0.31 ENST00000167106.4
ENST00000554237.1
VASH1
vasohibin 1
chr16_+_28763108 0.31 ENST00000357796.3
ENST00000550983.1
NPIPB9
nuclear pore complex interacting protein family, member B9
chr17_-_8198636 0.31 ENST00000577745.1
ENST00000579192.1
ENST00000396278.1
SLC25A35
solute carrier family 25, member 35
chr9_+_138235095 0.31 ENST00000320778.2
C9orf62
chromosome 9 open reading frame 62
chr5_-_19988339 0.31 ENST00000382275.1
CDH18
cadherin 18, type 2
chr9_-_127905736 0.31 ENST00000336505.6
ENST00000373549.4
SCAI
suppressor of cancer cell invasion
chr16_-_21868739 0.31 ENST00000415645.2
NPIPB4
nuclear pore complex interacting protein family, member B4
chr12_-_68726052 0.31 ENST00000540418.1
ENST00000411698.2
ENST00000393543.3
ENST00000303145.7
MDM1
Mdm1 nuclear protein homolog (mouse)
chr3_-_111314230 0.31 ENST00000317012.4
ZBED2
zinc finger, BED-type containing 2
chr9_-_116061145 0.31 ENST00000416588.2
RNF183
ring finger protein 183
chr20_-_50808525 0.31 ENST00000216923.4
ZFP64
ZFP64 zinc finger protein
chr8_+_133879193 0.31 ENST00000377869.1
ENST00000220616.4
TG
thyroglobulin
chr19_-_53770972 0.31 ENST00000311170.4
VN1R4
vomeronasal 1 receptor 4
chr3_+_127634312 0.31 ENST00000407609.3
KBTBD12
kelch repeat and BTB (POZ) domain containing 12
chr4_+_42399856 0.31 ENST00000319234.4
SHISA3
shisa family member 3
chr2_+_33701286 0.30 ENST00000403687.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr2_+_90198535 0.30 ENST00000390276.2
IGKV1D-12
immunoglobulin kappa variable 1D-12
chr19_+_42381173 0.30 ENST00000221972.3
CD79A
CD79a molecule, immunoglobulin-associated alpha
chr15_+_83776137 0.30 ENST00000322019.9
TM6SF1
transmembrane 6 superfamily member 1
chr1_+_154377669 0.30 ENST00000368485.3
ENST00000344086.4
IL6R
interleukin 6 receptor
chr14_+_23842018 0.30 ENST00000397242.2
ENST00000329715.2
IL25
interleukin 25
chr1_+_162760513 0.30 ENST00000367915.1
ENST00000367917.3
ENST00000254521.3
ENST00000367913.1
HSD17B7
hydroxysteroid (17-beta) dehydrogenase 7
chr14_-_77495007 0.30 ENST00000238647.3
IRF2BPL
interferon regulatory factor 2 binding protein-like
chr5_-_172662303 0.30 ENST00000517440.1
ENST00000329198.4
NKX2-5
NK2 homeobox 5
chr8_-_80993010 0.30 ENST00000537855.1
ENST00000520527.1
ENST00000517427.1
ENST00000448733.2
ENST00000379097.3
TPD52
tumor protein D52
chr17_+_37793378 0.29 ENST00000544210.2
ENST00000581894.1
ENST00000394250.4
ENST00000579479.1
ENST00000577248.1
ENST00000580611.1
STARD3
StAR-related lipid transfer (START) domain containing 3
chr1_+_6845578 0.29 ENST00000467404.2
ENST00000439411.2
CAMTA1
calmodulin binding transcription activator 1
chr2_+_173600514 0.29 ENST00000264111.6
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr21_+_45770009 0.29 ENST00000300482.5
ENST00000431901.1
TRPM2
transient receptor potential cation channel, subfamily M, member 2
chr6_+_35995488 0.29 ENST00000229795.3
MAPK14
mitogen-activated protein kinase 14
chrX_+_45364633 0.29 ENST00000435394.1
ENST00000609127.1
RP11-245M24.1
RP11-245M24.1
chr1_+_2160134 0.29 ENST00000378536.4
SKI
v-ski avian sarcoma viral oncogene homolog
chr9_+_90112767 0.29 ENST00000408954.3
DAPK1
death-associated protein kinase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of MESP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.6 GO:0052551 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.5 2.1 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.5 1.4 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.4 2.1 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.4 1.2 GO:0021571 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.4 1.1 GO:0002384 hepatic immune response(GO:0002384)
0.3 2.5 GO:0001661 conditioned taste aversion(GO:0001661)
0.3 1.4 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.3 1.4 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.3 1.0 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.2 0.8 GO:0021592 fourth ventricle development(GO:0021592)
0.2 0.2 GO:0097017 renal protein absorption(GO:0097017) renal albumin absorption(GO:0097018) regulation of renal albumin absorption(GO:2000532)
0.2 0.5 GO:0003162 atrioventricular node development(GO:0003162)
0.2 0.8 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.2 0.5 GO:0072237 carbon dioxide transmembrane transport(GO:0035378) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229) metanephric proximal tubule development(GO:0072237)
0.2 1.0 GO:0061441 renal artery morphogenesis(GO:0061441)
0.1 1.8 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.1 0.7 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.7 GO:0050917 sensory perception of umami taste(GO:0050917)
0.1 0.4 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.1 1.7 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.5 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.1 0.4 GO:0019085 early viral transcription(GO:0019085)
0.1 0.5 GO:0018032 protein amidation(GO:0018032)
0.1 0.3 GO:1903028 positive regulation of opsonization(GO:1903028)
0.1 0.6 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.1 1.0 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 1.1 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.1 0.3 GO:0086100 posterior midgut development(GO:0007497) endothelin receptor signaling pathway(GO:0086100)
0.1 0.3 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.1 0.3 GO:1990764 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.1 0.4 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.1 0.4 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 0.3 GO:0021793 chemorepulsion of branchiomotor axon(GO:0021793)
0.1 0.6 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.5 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.5 GO:0010728 regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.1 0.4 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.1 0.3 GO:0021913 glandular epithelial cell maturation(GO:0002071) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) type B pancreatic cell maturation(GO:0072560)
0.1 0.4 GO:0036115 fatty-acyl-CoA catabolic process(GO:0036115) malonyl-CoA metabolic process(GO:2001293)
0.1 0.3 GO:0003335 corneocyte development(GO:0003335)
0.1 0.1 GO:0010157 response to chlorate(GO:0010157)
0.1 0.2 GO:0001172 transcription, RNA-templated(GO:0001172) negative regulation of RNA interference(GO:1900369)
0.1 0.4 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 0.2 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.1 0.2 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.1 0.4 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1 0.3 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.1 0.2 GO:1905166 negative regulation of protein catabolic process in the vacuole(GO:1904351) negative regulation of lysosomal protein catabolic process(GO:1905166)
0.1 0.3 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.1 0.9 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 0.2 GO:0048850 hypophysis morphogenesis(GO:0048850)
0.1 0.6 GO:0034201 response to oleic acid(GO:0034201)
0.1 0.2 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.1 0.1 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.1 0.2 GO:0050894 determination of affect(GO:0050894)
0.1 2.0 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.1 0.1 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.1 0.2 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.1 0.3 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.1 0.1 GO:0050968 detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.1 0.2 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.1 0.8 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.1 0.2 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.1 0.2 GO:0001079 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.1 0.4 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.1 0.3 GO:0072248 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.1 0.6 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.1 0.2 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.4 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.1 0.3 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.1 0.5 GO:0015705 iodide transport(GO:0015705)
0.1 0.6 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.1 0.2 GO:1904772 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.1 0.3 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 0.2 GO:0032416 negative regulation of sodium:proton antiporter activity(GO:0032416)
0.1 0.2 GO:0060023 soft palate development(GO:0060023)
0.1 0.4 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.3 GO:0009439 cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
0.1 0.1 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.1 0.5 GO:0048733 sebaceous gland development(GO:0048733)
0.1 3.5 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 0.2 GO:0060018 astrocyte fate commitment(GO:0060018) renal vesicle induction(GO:0072034)
0.1 0.6 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 9.9 GO:0031424 keratinization(GO:0031424)
0.0 0.3 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.2 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.2 GO:2000721 pilomotor reflex(GO:0097195) positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0 0.1 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.2 GO:0007418 ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.0 0.4 GO:0060174 limb bud formation(GO:0060174)
0.0 0.9 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0 0.2 GO:0035811 regulation of systemic arterial blood pressure by vasopressin(GO:0001992) negative regulation of urine volume(GO:0035811)
0.0 0.4 GO:0055091 phospholipid homeostasis(GO:0055091)
0.0 0.1 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.0 0.3 GO:0009624 response to nematode(GO:0009624) eosinophil differentiation(GO:0030222)
0.0 0.2 GO:0036292 DNA rewinding(GO:0036292)
0.0 0.2 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.1 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.1 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.0 0.4 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.3 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.2 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0 0.2 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.0 0.7 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.1 GO:0002125 maternal aggressive behavior(GO:0002125) positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0 0.2 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 0.2 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.0 0.1 GO:0001694 histamine biosynthetic process(GO:0001694)
0.0 0.5 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.1 GO:1901074 regulation of engulfment of apoptotic cell(GO:1901074)
0.0 0.5 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.2 GO:2000664 positive regulation of interleukin-5 secretion(GO:2000664)
0.0 1.4 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.7 GO:0072189 ureter development(GO:0072189)
0.0 0.2 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.7 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.5 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.3 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0002525 acute inflammatory response to non-antigenic stimulus(GO:0002525) regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877)
0.0 0.2 GO:0045631 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.0 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.1 GO:0070904 L-ascorbic acid transport(GO:0015882) molecular hydrogen transport(GO:0015993) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.3 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.1 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.4 GO:0070673 response to interleukin-18(GO:0070673)
0.0 0.2 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.1 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 0.3 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.2 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.1 GO:0007343 egg activation(GO:0007343)
0.0 0.1 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.0 0.6 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.6 GO:0016180 snRNA processing(GO:0016180)
0.0 0.1 GO:0015911 plasma membrane long-chain fatty acid transport(GO:0015911)
0.0 0.1 GO:1903936 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.0 0.1 GO:0018874 benzoate metabolic process(GO:0018874)
0.0 0.2 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0 0.2 GO:0019236 response to pheromone(GO:0019236)
0.0 0.6 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 0.1 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.0 0.1 GO:0090301 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.2 GO:0032445 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.0 0.3 GO:0030238 male sex determination(GO:0030238)
0.0 1.5 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:0001834 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.0 0.5 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.1 GO:0006272 leading strand elongation(GO:0006272)
0.0 0.1 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.0 0.3 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.1 GO:0070384 Harderian gland development(GO:0070384)
0.0 0.6 GO:0046596 regulation of viral entry into host cell(GO:0046596)
0.0 0.1 GO:0042853 L-alanine metabolic process(GO:0042851) L-alanine catabolic process(GO:0042853)
0.0 0.2 GO:0010566 regulation of ketone biosynthetic process(GO:0010566)
0.0 0.4 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 0.1 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.0 0.1 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) negative regulation of interleukin-5 production(GO:0032714)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.1 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.0 0.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.2 GO:0006772 thiamine metabolic process(GO:0006772)
0.0 0.1 GO:0051594 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.3 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.6 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0 0.9 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.2 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.4 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.1 GO:0002316 follicular B cell differentiation(GO:0002316)
0.0 0.1 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.0 0.1 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.7 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.0 0.4 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.3 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.2 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 0.1 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.0 0.6 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 0.2 GO:1901374 acetate ester transport(GO:1901374)
0.0 0.3 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.1 GO:0032914 rostrocaudal neural tube patterning(GO:0021903) positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 1.1 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.1 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0 0.0 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.0 0.1 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.0 GO:1904387 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.0 0.5 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.1 GO:0035625 negative regulation of epinephrine secretion(GO:0032811) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.0 1.1 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.2 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.5 GO:0010842 retina layer formation(GO:0010842)
0.0 0.0 GO:0031179 peptide amidation(GO:0001519) peptide modification(GO:0031179)
0.0 0.2 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841)
0.0 0.1 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 1.3 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.3 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 0.1 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.1 GO:1903433 regulation of constitutive secretory pathway(GO:1903433)
0.0 0.1 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.2 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.1 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.3 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.0 0.3 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.2 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.1 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.0 0.2 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.0 GO:2000672 regulation of motor neuron apoptotic process(GO:2000671) negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.1 GO:0048672 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102) positive regulation of collateral sprouting(GO:0048672)
0.0 0.1 GO:0042048 olfactory behavior(GO:0042048)
0.0 0.2 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.4 GO:0035976 AP1 complex(GO:0035976)
0.3 1.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.2 0.7 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.2 0.6 GO:0020003 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.2 0.9 GO:0097513 myosin II filament(GO:0097513)
0.2 1.6 GO:0061689 tricellular tight junction(GO:0061689)
0.2 4.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.6 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 10.8 GO:0045095 keratin filament(GO:0045095)
0.1 0.8 GO:0019815 B cell receptor complex(GO:0019815)
0.1 3.4 GO:0000145 exocyst(GO:0000145)
0.1 0.2 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.1 1.0 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.2 GO:0005608 laminin-3 complex(GO:0005608)
0.1 1.0 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.2 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
0.1 0.3 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.1 0.5 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.2 GO:0031166 integral component of vacuolar membrane(GO:0031166)
0.1 0.4 GO:1990393 3M complex(GO:1990393)
0.1 0.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.6 GO:0032039 integrator complex(GO:0032039)
0.0 0.6 GO:0005915 zonula adherens(GO:0005915)
0.0 0.2 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.3 GO:1990635 proximal dendrite(GO:1990635)
0.0 1.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.0 0.4 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.2 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 0.4 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 1.5 GO:0019814 immunoglobulin complex(GO:0019814) immunoglobulin complex, circulating(GO:0042571)
0.0 0.3 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.1 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.6 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.1 GO:0005602 complement component C1 complex(GO:0005602)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.1 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.1 GO:0016342 catenin complex(GO:0016342)
0.0 0.0 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 1.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)
0.0 0.2 GO:0000124 SAGA complex(GO:0000124)
0.0 0.3 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.4 GO:0098576 lumenal side of membrane(GO:0098576)
0.0 0.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:1990812 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.0 0.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.2 GO:0031528 microvillus membrane(GO:0031528)
0.0 1.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.8 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.5 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.3 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.0 GO:0097058 CRLF-CLCF1 complex(GO:0097058)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.2 4.7 GO:0004383 guanylate cyclase activity(GO:0004383)
0.2 0.5 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.1 0.4 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 0.4 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 1.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 0.6 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.1 0.5 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 1.7 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.3 GO:0004962 endothelin receptor activity(GO:0004962)
0.1 0.3 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.1 0.1 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.1 0.3 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 0.3 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.1 0.7 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.3 GO:0043398 HLH domain binding(GO:0043398) calcium-induced calcium release activity(GO:0048763)
0.1 0.3 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.1 0.7 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.1 0.4 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.8 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.2 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.1 0.2 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 0.3 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.5 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 1.6 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.1 0.4 GO:0043426 MRF binding(GO:0043426)
0.1 0.2 GO:0031877 somatostatin receptor binding(GO:0031877)
0.1 0.7 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 0.2 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.1 0.2 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.1 1.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.4 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.1 0.2 GO:0070336 flap-structured DNA binding(GO:0070336)
0.1 0.6 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.1 0.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 3.7 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 0.3 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.2 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 0.3 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.3 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 0.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.5 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.6 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.0 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 0.3 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.2 GO:0047708 biotinidase activity(GO:0047708)
0.0 0.2 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.3 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.2 GO:0030395 lactose binding(GO:0030395)
0.0 2.0 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.2 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 0.2 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.2 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 0.6 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.2 GO:0004802 transketolase activity(GO:0004802)
0.0 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.2 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.2 GO:1903135 cupric ion binding(GO:1903135)
0.0 0.1 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.0 0.3 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.3 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.6 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.1 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.0 1.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.1 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.0 0.5 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.1 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.5 GO:0015250 water channel activity(GO:0015250)
0.0 0.3 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.1 GO:0015229 L-ascorbate:sodium symporter activity(GO:0008520) sodium-dependent multivitamin transmembrane transporter activity(GO:0008523) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.4 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.1 GO:0004368 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0 0.1 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 1.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.2 GO:0045159 myosin II binding(GO:0045159)
0.0 0.2 GO:0016015 morphogen activity(GO:0016015)
0.0 0.2 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0047977 hepoxilin-epoxide hydrolase activity(GO:0047977)
0.0 0.2 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.0 0.6 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0031893 vasopressin receptor binding(GO:0031893)
0.0 0.3 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.2 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.2 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.4 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.3 GO:0015278 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.2 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.1 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.2 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.2 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.5 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.1 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.0 0.2 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.1 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 1.3 GO:0019003 GDP binding(GO:0019003)
0.0 0.9 GO:0043531 ADP binding(GO:0043531)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.6 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.1 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.0 0.2 GO:0089720 caspase binding(GO:0089720)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.0 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.6 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.1 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.3 GO:0031005 filamin binding(GO:0031005)
0.0 0.2 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.1 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.0 GO:0005046 KDEL sequence binding(GO:0005046)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 1.1 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.0 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.3 GO:0043015 gamma-tubulin binding(GO:0043015)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 0.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 4.4 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 1.1 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.3 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 1.1 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.2 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.8 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.9 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.7 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 1.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.5 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 1.0 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.7 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.1 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.1 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.3 PID NOTCH PATHWAY Notch signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.4 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 3.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 0.8 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 3.0 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.7 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.7 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.0 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.5 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.9 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 2.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.8 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.5 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.1 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.0 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.1 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.5 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.2 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.2 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs