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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for MIXL1_GSX1_BSX_MEOX2_LHX4

Z-value: 0.71

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Transcription factors associated with MIXL1_GSX1_BSX_MEOX2_LHX4

Gene Symbol Gene ID Gene Info
MIXL1
ENSG00000185155.7 Mix paired-like homeobox
GSX1
ENSG00000169840.4 GS homeobox 1
BSX
ENSG00000188909.4 brain specific homeobox
MEOX2
ENSG00000106511.5 mesenchyme homeobox 2
LHX4
ENSG00000121454.4 LIM homeobox 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GSX1hg19_v2_chr13_+_28366780_283667800.301.5e-01Click!
MEOX2hg19_v2_chr7_-_15726296_15726437-0.164.6e-01Click!
LHX4hg19_v2_chr1_+_180199393_1801994260.125.6e-01Click!
MIXL1hg19_v2_chr1_+_226411319_226411366-0.019.7e-01Click!

Activity profile of MIXL1_GSX1_BSX_MEOX2_LHX4 motif

Sorted Z-values of MIXL1_GSX1_BSX_MEOX2_LHX4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_92777606 2.73 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chr6_+_127898312 1.75 ENST00000329722.7
C6orf58
chromosome 6 open reading frame 58
chr1_-_150738261 1.62 ENST00000448301.2
ENST00000368985.3
CTSS
cathepsin S
chr8_+_22424551 1.52 ENST00000523348.1
SORBS3
sorbin and SH3 domain containing 3
chr2_-_208031943 1.50 ENST00000421199.1
ENST00000457962.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr17_+_39261584 1.39 ENST00000391415.1
KRTAP4-9
keratin associated protein 4-9
chr11_-_117748138 1.37 ENST00000527717.1
FXYD6
FXYD domain containing ion transport regulator 6
chr2_+_152214098 1.33 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr11_-_117747434 1.32 ENST00000529335.2
ENST00000530956.1
ENST00000260282.4
FXYD6
FXYD domain containing ion transport regulator 6
chr4_+_169418255 1.31 ENST00000505667.1
ENST00000511948.1
PALLD
palladin, cytoskeletal associated protein
chr11_-_117747607 1.29 ENST00000540359.1
ENST00000539526.1
FXYD6
FXYD domain containing ion transport regulator 6
chr11_-_102651343 1.23 ENST00000279441.4
ENST00000539681.1
MMP10
matrix metallopeptidase 10 (stromelysin 2)
chr4_-_76944621 1.23 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chr11_-_72070206 1.22 ENST00000544382.1
CLPB
ClpB caseinolytic peptidase B homolog (E. coli)
chr6_+_151042224 1.17 ENST00000358517.2
PLEKHG1
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr2_+_103035102 1.17 ENST00000264260.2
IL18RAP
interleukin 18 receptor accessory protein
chr10_+_24497704 1.16 ENST00000376456.4
ENST00000458595.1
KIAA1217
KIAA1217
chr15_-_55562479 1.13 ENST00000564609.1
RAB27A
RAB27A, member RAS oncogene family
chr18_-_33709268 1.13 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
SLC39A6
solute carrier family 39 (zinc transporter), member 6
chr13_-_46716969 1.12 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chrX_+_144908928 1.11 ENST00000408967.2
TMEM257
transmembrane protein 257
chr12_-_88974236 1.04 ENST00000228280.5
ENST00000552044.1
ENST00000357116.4
KITLG
KIT ligand
chr12_-_91546926 0.97 ENST00000550758.1
DCN
decorin
chr15_-_55563072 0.94 ENST00000567380.1
ENST00000565972.1
ENST00000569493.1
RAB27A
RAB27A, member RAS oncogene family
chr5_-_150473127 0.94 ENST00000521001.1
TNIP1
TNFAIP3 interacting protein 1
chr8_-_90996459 0.93 ENST00000517337.1
ENST00000409330.1
NBN
nibrin
chr14_-_51027838 0.93 ENST00000555216.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr10_-_36812323 0.86 ENST00000543053.1
NAMPTL
nicotinamide phosphoribosyltransferase-like
chr7_-_28220354 0.85 ENST00000283928.5
JAZF1
JAZF zinc finger 1
chr8_+_50824233 0.84 ENST00000522124.1
SNTG1
syntrophin, gamma 1
chr9_-_16728161 0.84 ENST00000603713.1
ENST00000603313.1
BNC2
basonuclin 2
chr18_-_3219847 0.84 ENST00000261606.7
MYOM1
myomesin 1
chr11_+_33061543 0.82 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
TCP11L1
t-complex 11, testis-specific-like 1
chr15_-_55562582 0.81 ENST00000396307.2
RAB27A
RAB27A, member RAS oncogene family
chr4_+_169418195 0.80 ENST00000261509.6
ENST00000335742.7
PALLD
palladin, cytoskeletal associated protein
chr2_-_136678123 0.80 ENST00000422708.1
DARS
aspartyl-tRNA synthetase
chr2_+_169926047 0.76 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr7_-_22234381 0.75 ENST00000458533.1
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr17_-_77924627 0.73 ENST00000572862.1
ENST00000573782.1
ENST00000574427.1
ENST00000570373.1
ENST00000340848.7
ENST00000576768.1
TBC1D16
TBC1 domain family, member 16
chr5_-_24645078 0.72 ENST00000264463.4
CDH10
cadherin 10, type 2 (T2-cadherin)
chr2_+_68961905 0.72 ENST00000295381.3
ARHGAP25
Rho GTPase activating protein 25
chr6_-_87804815 0.71 ENST00000369582.2
CGA
glycoprotein hormones, alpha polypeptide
chr17_-_39150385 0.71 ENST00000391586.1
KRTAP3-3
keratin associated protein 3-3
chr1_+_101003687 0.70 ENST00000315033.4
GPR88
G protein-coupled receptor 88
chr17_-_39623681 0.69 ENST00000225899.3
KRT32
keratin 32
chr2_+_68961934 0.69 ENST00000409202.3
ARHGAP25
Rho GTPase activating protein 25
chr3_-_157221380 0.69 ENST00000468233.1
VEPH1
ventricular zone expressed PH domain-containing 1
chr17_+_59489112 0.68 ENST00000335108.2
C17orf82
chromosome 17 open reading frame 82
chr12_-_51422017 0.68 ENST00000394904.3
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr7_+_142919130 0.66 ENST00000408947.3
TAS2R40
taste receptor, type 2, member 40
chr11_-_13517565 0.65 ENST00000282091.1
ENST00000529816.1
PTH
parathyroid hormone
chr4_-_120243545 0.64 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr6_+_126240442 0.64 ENST00000448104.1
ENST00000438495.1
ENST00000444128.1
NCOA7
nuclear receptor coactivator 7
chr11_-_104905840 0.63 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
CASP1
caspase 1, apoptosis-related cysteine peptidase
chr3_-_157221357 0.62 ENST00000494677.1
VEPH1
ventricular zone expressed PH domain-containing 1
chr14_-_72458326 0.61 ENST00000542853.1
AC005477.1
AC005477.1
chrX_-_13835147 0.60 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chr10_+_13141585 0.60 ENST00000378764.2
OPTN
optineurin
chr18_-_5396271 0.59 ENST00000579951.1
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr6_-_66417107 0.59 ENST00000370621.3
ENST00000370618.3
ENST00000503581.1
ENST00000393380.2
EYS
eyes shut homolog (Drosophila)
chr10_-_49860525 0.58 ENST00000435790.2
ARHGAP22
Rho GTPase activating protein 22
chr8_+_86157699 0.57 ENST00000321764.3
CA13
carbonic anhydrase XIII
chr1_-_173174681 0.56 ENST00000367718.1
TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr10_+_13141441 0.56 ENST00000263036.5
OPTN
optineurin
chr3_+_182983090 0.55 ENST00000465010.1
B3GNT5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr5_+_66300446 0.55 ENST00000261569.7
MAST4
microtubule associated serine/threonine kinase family member 4
chr4_-_139163491 0.54 ENST00000280612.5
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chrX_-_15332665 0.54 ENST00000537676.1
ENST00000344384.4
ASB11
ankyrin repeat and SOCS box containing 11
chr22_+_18632666 0.53 ENST00000215794.7
USP18
ubiquitin specific peptidase 18
chr11_-_55703876 0.53 ENST00000301532.3
OR5I1
olfactory receptor, family 5, subfamily I, member 1
chrX_-_68385274 0.53 ENST00000374584.3
ENST00000590146.1
PJA1
praja ring finger 1, E3 ubiquitin protein ligase
chr10_+_114710425 0.53 ENST00000352065.5
ENST00000369395.1
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr1_+_225600404 0.53 ENST00000366845.2
AC092811.1
AC092811.1
chr2_+_68962014 0.52 ENST00000467265.1
ARHGAP25
Rho GTPase activating protein 25
chr9_+_12693336 0.52 ENST00000381137.2
ENST00000388918.5
TYRP1
tyrosinase-related protein 1
chr21_-_37914898 0.51 ENST00000399136.1
CLDN14
claudin 14
chr2_+_162087577 0.51 ENST00000439442.1
TANK
TRAF family member-associated NFKB activator
chr3_+_111393501 0.51 ENST00000393934.3
PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr11_-_121986923 0.50 ENST00000560104.1
BLID
BH3-like motif containing, cell death inducer
chr13_-_41593425 0.50 ENST00000239882.3
ELF1
E74-like factor 1 (ets domain transcription factor)
chr16_+_57279004 0.50 ENST00000219204.3
ARL2BP
ADP-ribosylation factor-like 2 binding protein
chr12_-_10959892 0.50 ENST00000240615.2
TAS2R8
taste receptor, type 2, member 8
chr5_+_125758865 0.50 ENST00000542322.1
ENST00000544396.1
GRAMD3
GRAM domain containing 3
chr15_+_75080883 0.49 ENST00000567571.1
CSK
c-src tyrosine kinase
chr5_+_125758813 0.49 ENST00000285689.3
ENST00000515200.1
GRAMD3
GRAM domain containing 3
chr18_-_33702078 0.49 ENST00000586829.1
SLC39A6
solute carrier family 39 (zinc transporter), member 6
chr4_+_169013666 0.48 ENST00000359299.3
ANXA10
annexin A10
chr11_-_104972158 0.48 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
CASP1
CARD16
CARD17
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr7_-_22233442 0.48 ENST00000401957.2
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr17_-_39211463 0.47 ENST00000542910.1
ENST00000398477.1
KRTAP2-2
keratin associated protein 2-2
chr7_-_33102338 0.47 ENST00000610140.1
NT5C3A
5'-nucleotidase, cytosolic IIIA
chr17_-_39324424 0.47 ENST00000391356.2
KRTAP4-3
keratin associated protein 4-3
chr3_+_130569429 0.47 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr7_-_33102399 0.47 ENST00000242210.7
NT5C3A
5'-nucleotidase, cytosolic IIIA
chr15_+_64680003 0.46 ENST00000261884.3
TRIP4
thyroid hormone receptor interactor 4
chr10_+_13142075 0.45 ENST00000378757.2
ENST00000430081.1
ENST00000378752.3
ENST00000378748.3
OPTN
optineurin
chr10_+_126630692 0.45 ENST00000359653.4
ZRANB1
zinc finger, RAN-binding domain containing 1
chr3_-_108248169 0.45 ENST00000273353.3
MYH15
myosin, heavy chain 15
chr7_-_111032971 0.45 ENST00000450877.1
IMMP2L
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr5_-_146781153 0.45 ENST00000520473.1
DPYSL3
dihydropyrimidinase-like 3
chr8_-_116504448 0.44 ENST00000518018.1
TRPS1
trichorhinophalangeal syndrome I
chrX_+_135388147 0.44 ENST00000394141.1
GPR112
G protein-coupled receptor 112
chr5_-_142780280 0.44 ENST00000424646.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr5_-_147162078 0.43 ENST00000507386.1
JAKMIP2
janus kinase and microtubule interacting protein 2
chr18_+_32173276 0.43 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
DTNA
dystrobrevin, alpha
chr3_-_194188956 0.42 ENST00000256031.4
ENST00000446356.1
ATP13A3
ATPase type 13A3
chr19_+_48949030 0.42 ENST00000253237.5
GRWD1
glutamate-rich WD repeat containing 1
chr4_+_66536248 0.42 ENST00000514260.1
ENST00000507117.1
RP11-807H7.1
RP11-807H7.1
chrX_+_11129388 0.41 ENST00000321143.4
ENST00000380763.3
ENST00000380762.4
HCCS
holocytochrome c synthase
chr6_+_135502501 0.41 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr11_-_107729887 0.41 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr1_-_11024258 0.41 ENST00000418570.2
C1orf127
chromosome 1 open reading frame 127
chr8_+_101170563 0.41 ENST00000520508.1
ENST00000388798.2
SPAG1
sperm associated antigen 1
chr16_+_56970567 0.41 ENST00000563911.1
HERPUD1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr6_-_32908792 0.41 ENST00000418107.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr7_-_25268104 0.40 ENST00000222674.2
NPVF
neuropeptide VF precursor
chr5_-_95297534 0.40 ENST00000513343.1
ENST00000431061.2
ELL2
elongation factor, RNA polymerase II, 2
chr2_+_161993465 0.40 ENST00000457476.1
TANK
TRAF family member-associated NFKB activator
chr1_-_101360331 0.40 ENST00000416479.1
ENST00000370113.3
EXTL2
exostosin-like glycosyltransferase 2
chr18_+_61554932 0.39 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
SERPINB2
serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr8_+_7738726 0.39 ENST00000314357.3
DEFB103A
defensin, beta 103A
chr13_+_49551020 0.39 ENST00000541916.1
FNDC3A
fibronectin type III domain containing 3A
chr4_-_39979576 0.39 ENST00000303538.8
ENST00000503396.1
PDS5A
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr4_+_36283213 0.39 ENST00000357504.3
DTHD1
death domain containing 1
chr21_-_42219065 0.38 ENST00000400454.1
DSCAM
Down syndrome cell adhesion molecule
chr12_-_6233828 0.38 ENST00000572068.1
ENST00000261405.5
VWF
von Willebrand factor
chr4_-_76957214 0.38 ENST00000306621.3
CXCL11
chemokine (C-X-C motif) ligand 11
chr4_-_89951028 0.38 ENST00000506913.1
FAM13A
family with sequence similarity 13, member A
chr1_-_165414414 0.38 ENST00000359842.5
RXRG
retinoid X receptor, gamma
chr8_+_9953214 0.37 ENST00000382490.5
MSRA
methionine sulfoxide reductase A
chr8_+_9953061 0.36 ENST00000522907.1
ENST00000528246.1
MSRA
methionine sulfoxide reductase A
chr2_-_203735484 0.36 ENST00000420558.1
ENST00000418208.1
ICA1L
islet cell autoantigen 1,69kDa-like
chr10_-_115904361 0.36 ENST00000428953.1
ENST00000543782.1
C10orf118
chromosome 10 open reading frame 118
chr10_-_24770632 0.35 ENST00000596413.1
AL353583.1
AL353583.1
chr17_-_39306054 0.35 ENST00000343246.4
KRTAP4-5
keratin associated protein 4-5
chr7_+_150065278 0.35 ENST00000519397.1
ENST00000479668.1
ENST00000540729.1
REPIN1
replication initiator 1
chr11_-_36619771 0.34 ENST00000311485.3
ENST00000527033.1
ENST00000532616.1
RAG2
recombination activating gene 2
chr2_+_162016804 0.34 ENST00000392749.2
ENST00000440506.1
TANK
TRAF family member-associated NFKB activator
chr14_+_22748980 0.34 ENST00000390465.2
TRAV38-2DV8
T cell receptor alpha variable 38-2/delta variable 8
chr11_+_120973375 0.34 ENST00000264037.2
TECTA
tectorin alpha
chr17_+_45000483 0.34 ENST00000576910.2
ENST00000439730.2
ENST00000393456.2
ENST00000415811.2
ENST00000575949.1
ENST00000225567.4
ENST00000572403.1
ENST00000570879.1
GOSR2
golgi SNAP receptor complex member 2
chr11_+_102188224 0.34 ENST00000263464.3
BIRC3
baculoviral IAP repeat containing 3
chr2_-_88285309 0.34 ENST00000420840.2
RGPD2
RANBP2-like and GRIP domain containing 2
chr8_+_42873548 0.34 ENST00000533338.1
ENST00000534420.1
HOOK3
RP11-598P20.5
hook microtubule-tethering protein 3
Uncharacterized protein
chr6_+_153552455 0.34 ENST00000392385.2
AL590867.1
Uncharacterized protein; cDNA FLJ59044, highly similar to LINE-1 reverse transcriptase homolog
chr8_-_57026541 0.34 ENST00000311923.1
MOS
v-mos Moloney murine sarcoma viral oncogene homolog
chr1_+_160160283 0.34 ENST00000368079.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr17_-_72772462 0.34 ENST00000582870.1
ENST00000581136.1
ENST00000357814.3
ENST00000579218.1
ENST00000583476.1
ENST00000580301.1
ENST00000583757.1
ENST00000582524.1
NAT9
N-acetyltransferase 9 (GCN5-related, putative)
chr4_-_89205705 0.33 ENST00000295908.7
ENST00000510548.2
ENST00000508256.1
PPM1K
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr18_+_32556892 0.33 ENST00000591734.1
ENST00000413393.1
ENST00000589180.1
ENST00000587359.1
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr8_-_7287870 0.33 ENST00000318124.3
DEFB103B
defensin, beta 103B
chr1_-_95391315 0.33 ENST00000545882.1
ENST00000415017.1
CNN3
calponin 3, acidic
chr14_-_21737551 0.33 ENST00000554891.1
ENST00000555883.1
ENST00000553753.1
ENST00000555914.1
ENST00000557336.1
ENST00000555215.1
ENST00000556628.1
ENST00000555137.1
ENST00000556226.1
ENST00000555309.1
ENST00000556142.1
ENST00000554969.1
ENST00000554455.1
ENST00000556513.1
ENST00000557201.1
ENST00000420743.2
ENST00000557768.1
ENST00000553300.1
ENST00000554383.1
ENST00000554539.1
HNRNPC
heterogeneous nuclear ribonucleoprotein C (C1/C2)
chr13_-_44735393 0.32 ENST00000400419.1
SMIM2
small integral membrane protein 2
chrX_-_130423200 0.32 ENST00000361420.3
IGSF1
immunoglobulin superfamily, member 1
chr14_-_101295407 0.32 ENST00000596284.1
AL117190.2
AL117190.2
chr20_+_18488137 0.32 ENST00000450074.1
ENST00000262544.2
ENST00000336714.3
ENST00000377475.3
SEC23B
Sec23 homolog B (S. cerevisiae)
chr17_+_42785976 0.32 ENST00000393547.2
ENST00000398338.3
DBF4B
DBF4 homolog B (S. cerevisiae)
chr18_+_57567180 0.31 ENST00000316660.6
ENST00000269518.9
PMAIP1
phorbol-12-myristate-13-acetate-induced protein 1
chr7_+_50348268 0.31 ENST00000438033.1
ENST00000439701.1
IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr5_-_95297678 0.30 ENST00000237853.4
ELL2
elongation factor, RNA polymerase II, 2
chr1_+_160160346 0.30 ENST00000368078.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr5_-_13944652 0.30 ENST00000265104.4
DNAH5
dynein, axonemal, heavy chain 5
chr6_+_26365443 0.30 ENST00000527422.1
ENST00000356386.2
ENST00000396934.3
ENST00000377708.2
ENST00000396948.1
ENST00000508906.2
BTN3A2
butyrophilin, subfamily 3, member A2
chr4_-_103749205 0.30 ENST00000508249.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr21_-_43346790 0.30 ENST00000329623.7
C2CD2
C2 calcium-dependent domain containing 2
chr10_-_14372870 0.30 ENST00000357447.2
FRMD4A
FERM domain containing 4A
chr18_-_71959159 0.29 ENST00000494131.2
ENST00000397914.4
ENST00000340533.4
CYB5A
cytochrome b5 type A (microsomal)
chr14_+_22465771 0.29 ENST00000390445.2
TRAV17
T cell receptor alpha variable 17
chr6_+_26402465 0.29 ENST00000476549.2
ENST00000289361.6
ENST00000450085.2
ENST00000425234.2
ENST00000427334.1
ENST00000506698.1
BTN3A1
butyrophilin, subfamily 3, member A1
chr2_-_61697862 0.29 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr17_-_39254391 0.29 ENST00000333822.4
KRTAP4-8
keratin associated protein 4-8
chr22_-_32651326 0.29 ENST00000266086.4
SLC5A4
solute carrier family 5 (glucose activated ion channel), member 4
chr10_+_18549645 0.29 ENST00000396576.2
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr6_-_138539627 0.29 ENST00000527246.2
PBOV1
prostate and breast cancer overexpressed 1
chr12_-_112123524 0.29 ENST00000327551.6
BRAP
BRCA1 associated protein
chr2_-_175711133 0.28 ENST00000409597.1
ENST00000413882.1
CHN1
chimerin 1
chr16_+_12059050 0.28 ENST00000396495.3
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr5_-_87516448 0.28 ENST00000511218.1
TMEM161B
transmembrane protein 161B
chr10_+_24755416 0.28 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
KIAA1217
chr6_+_29274403 0.28 ENST00000377160.2
OR14J1
olfactory receptor, family 14, subfamily J, member 1
chr3_+_35721106 0.27 ENST00000474696.1
ENST00000412048.1
ENST00000396482.2
ENST00000432682.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr14_+_22739823 0.27 ENST00000390464.2
TRAV38-1
T cell receptor alpha variable 38-1
chr8_+_107460147 0.27 ENST00000442977.2
OXR1
oxidation resistance 1
chr8_+_38585704 0.27 ENST00000519416.1
ENST00000520615.1
TACC1
transforming, acidic coiled-coil containing protein 1
chr2_+_158114051 0.27 ENST00000259056.4
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr4_-_103998439 0.27 ENST00000503230.1
ENST00000503818.1
SLC9B2
solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
chr1_+_160370344 0.27 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr11_+_102188272 0.27 ENST00000532808.1
BIRC3
baculoviral IAP repeat containing 3
chr4_-_76928641 0.27 ENST00000264888.5
CXCL9
chemokine (C-X-C motif) ligand 9
chr2_+_162016916 0.26 ENST00000405852.1
TANK
TRAF family member-associated NFKB activator
chr9_+_12775011 0.26 ENST00000319264.3
LURAP1L
leucine rich adaptor protein 1-like
chr8_-_131399110 0.26 ENST00000521426.1
ASAP1
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr4_+_70796784 0.26 ENST00000246891.4
ENST00000444405.3
CSN1S1
casein alpha s1
chr2_-_163008903 0.26 ENST00000418842.2
ENST00000375497.3
GCG
glucagon
chr5_+_125695805 0.26 ENST00000513040.1
GRAMD3
GRAM domain containing 3
chr18_-_3220106 0.26 ENST00000356443.4
ENST00000400569.3
MYOM1
myomesin 1
chr1_+_183774240 0.26 ENST00000360851.3
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr17_-_60142609 0.26 ENST00000397786.2
MED13
mediator complex subunit 13
chr4_-_116034979 0.26 ENST00000264363.2
NDST4
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4

Network of associatons between targets according to the STRING database.

First level regulatory network of MIXL1_GSX1_BSX_MEOX2_LHX4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.9 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.3 1.0 GO:0033025 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.3 2.0 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.3 1.2 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.3 1.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.3 0.8 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.2 2.9 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.2 0.9 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.2 0.7 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.2 0.7 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.2 1.9 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.2 0.6 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.2 0.7 GO:0061743 motor learning(GO:0061743)
0.2 1.8 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.2 0.5 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 0.4 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 1.2 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.1 0.4 GO:1904897 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.1 0.7 GO:0015692 lead ion transport(GO:0015692)
0.1 0.7 GO:1902730 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1 0.7 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 0.3 GO:0044771 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.1 0.4 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.1 2.2 GO:0003334 keratinocyte development(GO:0003334)
0.1 1.0 GO:1900378 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.1 0.3 GO:0061341 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.1 0.3 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.1 0.1 GO:0021856 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)
0.1 0.1 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.1 0.7 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.4 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 1.0 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 1.4 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 0.2 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.1 1.1 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.2 GO:0042040 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.1 0.8 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 0.7 GO:0030091 protein repair(GO:0030091)
0.1 0.5 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.1 1.0 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.3 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1 0.2 GO:0045404 negative regulation of tolerance induction(GO:0002644) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.1 0.5 GO:0042997 negative regulation of low-density lipoprotein particle clearance(GO:0010989) negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.1 0.2 GO:0002384 hepatic immune response(GO:0002384)
0.1 0.2 GO:1904647 response to rotenone(GO:1904647)
0.1 0.6 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.2 GO:0061114 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.1 0.6 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.1 0.4 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 0.3 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1 0.1 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.1 0.8 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 0.1 GO:0048733 sebaceous gland development(GO:0048733)
0.1 0.2 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 1.4 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.0 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.0 1.5 GO:0030728 ovulation(GO:0030728)
0.0 0.2 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.2 GO:1990523 bone regeneration(GO:1990523)
0.0 0.3 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.4 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.5 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.2 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.4 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 3.9 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 1.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 0.3 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.2 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.3 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.2 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.4 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.2 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.2 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.5 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.2 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.1 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.3 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.2 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.0 0.1 GO:0051598 meiotic recombination checkpoint(GO:0051598)
0.0 0.2 GO:0061107 seminal vesicle development(GO:0061107)
0.0 0.1 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.0 0.2 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.2 GO:0003383 apical constriction(GO:0003383)
0.0 0.4 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0 0.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.0 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.0 0.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.1 GO:0060166 olfactory pit development(GO:0060166)
0.0 0.2 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.2 GO:0090400 stress-induced premature senescence(GO:0090400)
0.0 0.2 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.1 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 0.5 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.4 GO:1900118 negative regulation of execution phase of apoptosis(GO:1900118)
0.0 0.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.2 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.1 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466) mitochondrial membrane fission(GO:0090149)
0.0 0.1 GO:0035962 response to interleukin-13(GO:0035962)
0.0 0.6 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 0.8 GO:0043586 tongue development(GO:0043586)
0.0 0.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 1.0 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0018283 metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
0.0 0.2 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.2 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.0 0.6 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.4 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.1 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.1 GO:0098501 polynucleotide dephosphorylation(GO:0098501)
0.0 0.1 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.0 0.5 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.1 GO:0090298 base-excision repair, DNA ligation(GO:0006288) negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859)
0.0 0.1 GO:0042746 regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) circadian sleep/wake cycle, wakefulness(GO:0042746)
0.0 0.5 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.3 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.0 0.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.2 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.0 0.2 GO:1903286 regulation of potassium ion import(GO:1903286) regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.2 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.5 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.2 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.1 GO:1904798 positive regulation of core promoter binding(GO:1904798)
0.0 0.3 GO:0019532 oxalate transport(GO:0019532)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.0 0.5 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.1 GO:0009441 glycolate metabolic process(GO:0009441)
0.0 0.7 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.6 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.6 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.2 GO:1904386 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.0 0.2 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 0.1 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
0.0 0.1 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.0 0.6 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.1 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.0 0.9 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.0 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.1 GO:0021893 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.0 0.3 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.2 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.0 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.0 0.4 GO:0060009 Sertoli cell development(GO:0060009)
0.0 1.6 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.7 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 0.2 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.4 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.0 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.0 0.3 GO:2000121 regulation of removal of superoxide radicals(GO:2000121)
0.0 0.0 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.0 0.0 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.0 GO:0009946 proximal/distal axis specification(GO:0009946)
0.0 0.0 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.0 2.1 GO:0042633 molting cycle(GO:0042303) hair cycle(GO:0042633)
0.0 0.1 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.0 0.1 GO:0035627 ceramide transport(GO:0035627)
0.0 0.7 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.2 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.1 GO:0043455 regulation of secondary metabolic process(GO:0043455)
0.0 0.1 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.0 0.1 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.1 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.0 0.5 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.1 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0 0.2 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.1 GO:0001956 positive regulation of neurotransmitter secretion(GO:0001956)
0.0 0.1 GO:0072023 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.0 0.1 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.1 GO:0010958 regulation of amino acid import(GO:0010958)
0.0 0.0 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.0 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0 0.1 GO:0046462 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.2 GO:0034116 positive regulation of heterotypic cell-cell adhesion(GO:0034116)
0.0 0.7 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.0 0.3 GO:0051642 centrosome localization(GO:0051642)
0.0 0.0 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.1 GO:1901142 insulin metabolic process(GO:1901142)
0.0 0.4 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.0 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.0 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.0 0.0 GO:0038027 apolipoprotein A-I-mediated signaling pathway(GO:0038027)
0.0 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.0 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.2 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.0 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.1 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.2 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.2 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.0 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.1 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.0 0.0 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 0.1 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.1 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.0 GO:0018874 benzoate metabolic process(GO:0018874)
0.0 0.0 GO:0061055 myotome development(GO:0061055)
0.0 0.0 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.0 0.1 GO:1902268 polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.0 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.0 0.3 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.1 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.2 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.0 GO:0016999 antibiotic metabolic process(GO:0016999)
0.0 0.1 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.0 0.5 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.2 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.2 GO:0071420 cellular response to histamine(GO:0071420)
0.0 1.7 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.0 GO:0052331 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.0 0.9 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 0.1 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.2 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.2 3.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.2 1.6 GO:0036021 endolysosome lumen(GO:0036021)
0.2 1.3 GO:0097179 protease inhibitor complex(GO:0097179)
0.1 0.7 GO:0070826 paraferritin complex(GO:0070826)
0.1 1.2 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.7 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 0.6 GO:0014802 terminal cisterna(GO:0014802)
0.1 0.8 GO:0016013 syntrophin complex(GO:0016013)
0.1 0.4 GO:1990037 Lewy body core(GO:1990037)
0.1 0.9 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.3 GO:0060187 cell pole(GO:0060187)
0.1 0.1 GO:0032127 dense core granule membrane(GO:0032127)
0.0 0.3 GO:0070695 FHF complex(GO:0070695)
0.0 3.2 GO:0002102 podosome(GO:0002102)
0.0 0.7 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 1.7 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)
0.0 0.8 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.7 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.7 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.7 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.3 GO:0036157 outer dynein arm(GO:0036157)
0.0 2.2 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.4 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.3 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.4 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.2 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.2 GO:0071953 elastic fiber(GO:0071953)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.0 GO:0043159 acrosomal matrix(GO:0043159)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.2 GO:0043219 lateral loop(GO:0043219)
0.0 1.4 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 1.3 GO:0045095 keratin filament(GO:0045095)
0.0 0.4 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.1 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.4 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.5 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.0 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
0.0 0.5 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.1 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.2 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.1 GO:1990597 AIP1-IRE1 complex(GO:1990597)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.2 GO:0032982 myosin filament(GO:0032982)
0.0 0.1 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.6 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.1 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.0 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.3 1.0 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.3 2.0 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.2 0.7 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.2 0.9 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.2 0.8 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 0.7 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 0.7 GO:0015087 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 3.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 2.8 GO:0031489 myosin V binding(GO:0031489)
0.1 0.5 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.1 0.4 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.4 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.1 0.4 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 1.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.3 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 0.4 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.1 2.1 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 0.8 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1 0.2 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.1 0.2 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 4.2 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.5 GO:0034711 inhibin binding(GO:0034711)
0.1 0.2 GO:0008431 vitamin E binding(GO:0008431)
0.1 0.2 GO:0004915 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.1 1.2 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.2 GO:0002113 interleukin-33 binding(GO:0002113)
0.1 0.2 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.1 1.3 GO:0017166 vinculin binding(GO:0017166)
0.1 0.2 GO:0043337 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.0 0.2 GO:0016499 orexin receptor activity(GO:0016499)
0.0 1.8 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.9 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.8 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.3 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.5 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 1.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.3 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.2 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.9 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0 1.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.0 0.7 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0019770 IgG receptor activity(GO:0019770)
0.0 0.8 GO:0048018 receptor agonist activity(GO:0048018)
0.0 1.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.4 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.2 GO:0019863 IgE binding(GO:0019863)
0.0 0.2 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.1 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.0 0.3 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.4 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.7 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.1 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.0 1.5 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 0.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.9 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0097363 protein N-acetylglucosaminyltransferase activity(GO:0016262) protein O-GlcNAc transferase activity(GO:0097363)
0.0 1.2 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.0 0.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 1.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.6 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.4 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.0 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.0 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.0 0.2 GO:0032190 acrosin binding(GO:0032190)
0.0 0.2 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.0 GO:0001147 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.0 0.1 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.0 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0 0.1 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.0 0.2 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.1 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.3 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.1 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.0 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.1 GO:0002046 opsin binding(GO:0002046)
0.0 0.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.2 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.4 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.0 GO:0016015 morphogen activity(GO:0016015)
0.0 0.1 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.0 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.0 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.8 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 2.3 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 1.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 3.1 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.7 PID ARF 3PATHWAY Arf1 pathway
0.0 0.5 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.2 ST STAT3 PATHWAY STAT3 Pathway
0.0 1.2 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.0 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.3 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.6 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 0.2 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.6 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.1 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.8 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.3 PID EPHRINB REV PATHWAY Ephrin B reverse signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.6 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 2.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 1.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 0.8 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.8 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 1.2 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 1.7 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 1.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 1.0 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 2.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.5 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 1.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.7 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.2 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.6 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 1.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.8 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.5 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.0 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.7 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.3 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.3 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.6 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.4 REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION Genes involved in Incretin Synthesis, Secretion, and Inactivation
0.0 0.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.6 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.3 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.3 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.2 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.0 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.0 0.3 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 2.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.0 REACTOME BILE ACID AND BILE SALT METABOLISM Genes involved in Bile acid and bile salt metabolism
0.0 0.2 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling