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Inflammatory response time course, HUVEC (Wada et al., 2009)
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Results for MLX_USF2_USF1_PAX2
Z-value: 2.25
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Transcription factors associated with MLX_USF2_USF1_PAX2
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
MLX
|
ENSG00000108788.7 | MAX dimerization protein MLX |
|
USF2
|
ENSG00000105698.11 | upstream transcription factor 2, c-fos interacting |
|
USF1
|
ENSG00000158773.10 | upstream transcription factor 1 |
|
PAX2
|
ENSG00000075891.17 | paired box 2 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| PAX2 | hg19_v2_chr10_+_102505468_102505546 | 0.60 | 1.5e-03 | Click! |
| USF1 | hg19_v2_chr1_-_161014731_161014788, hg19_v2_chr1_-_161015752_161015778 | -0.55 | 4.4e-03 | Click! |
| MLX | hg19_v2_chr17_+_40719073_40719092 | -0.50 | 1.1e-02 | Click! |
| USF2 | hg19_v2_chr19_+_35759968_35760042 | 0.36 | 7.4e-02 | Click! |
Activity profile of MLX_USF2_USF1_PAX2 motif
Sorted Z-values of MLX_USF2_USF1_PAX2 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr1_+_221051699 | 15.23 |
ENST00000366903.6
|
HLX
|
H2.0-like homeobox |
| chr14_-_54420133 | 13.50 |
ENST00000559501.1
ENST00000558984.1 |
BMP4
|
bone morphogenetic protein 4 |
| chr8_+_120220561 | 11.58 |
ENST00000276681.6
|
MAL2
|
mal, T-cell differentiation protein 2 (gene/pseudogene) |
| chr17_-_46688334 | 11.47 |
ENST00000239165.7
|
HOXB7
|
homeobox B7 |
| chr14_-_54955721 | 9.57 |
ENST00000554908.1
|
GMFB
|
glia maturation factor, beta |
| chr3_-_122512619 | 9.54 |
ENST00000383659.1
ENST00000306103.2 |
HSPBAP1
|
HSPB (heat shock 27kDa) associated protein 1 |
| chr17_-_58469591 | 9.45 |
ENST00000589335.1
|
USP32
|
ubiquitin specific peptidase 32 |
| chr11_+_67159416 | 9.19 |
ENST00000307980.2
ENST00000544620.1 |
RAD9A
|
RAD9 homolog A (S. pombe) |
| chr11_+_59522837 | 8.96 |
ENST00000437946.2
|
STX3
|
syntaxin 3 |
| chr11_-_18343669 | 8.51 |
ENST00000396253.3
ENST00000349215.3 ENST00000438420.2 |
HPS5
|
Hermansky-Pudlak syndrome 5 |
| chr1_-_11866034 | 7.87 |
ENST00000376590.3
|
MTHFR
|
methylenetetrahydrofolate reductase (NAD(P)H) |
| chr2_+_148778570 | 7.79 |
ENST00000407073.1
|
MBD5
|
methyl-CpG binding domain protein 5 |
| chr3_+_112280857 | 7.65 |
ENST00000492406.1
ENST00000468642.1 |
SLC35A5
|
solute carrier family 35, member A5 |
| chr14_-_74551096 | 7.55 |
ENST00000350259.4
|
ALDH6A1
|
aldehyde dehydrogenase 6 family, member A1 |
| chr22_-_36903101 | 7.37 |
ENST00000397224.4
|
FOXRED2
|
FAD-dependent oxidoreductase domain containing 2 |
| chr12_+_93964158 | 7.12 |
ENST00000549206.1
|
SOCS2
|
suppressor of cytokine signaling 2 |
| chrX_+_55744228 | 7.10 |
ENST00000262850.7
|
RRAGB
|
Ras-related GTP binding B |
| chr1_-_113498616 | 6.99 |
ENST00000433570.4
ENST00000538576.1 ENST00000458229.1 |
SLC16A1
|
solute carrier family 16 (monocarboxylate transporter), member 1 |
| chr7_-_27183263 | 6.75 |
ENST00000222726.3
|
HOXA5
|
homeobox A5 |
| chr12_+_93964746 | 6.67 |
ENST00000536696.2
|
SOCS2
|
suppressor of cytokine signaling 2 |
| chr1_+_61869748 | 6.53 |
ENST00000357977.5
|
NFIA
|
nuclear factor I/A |
| chrX_+_118108601 | 6.50 |
ENST00000371628.3
|
LONRF3
|
LON peptidase N-terminal domain and ring finger 3 |
| chrX_+_55744166 | 6.41 |
ENST00000374941.4
ENST00000414239.1 |
RRAGB
|
Ras-related GTP binding B |
| chr11_+_7534999 | 6.32 |
ENST00000528947.1
ENST00000299492.4 |
PPFIBP2
|
PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| chrX_+_53123314 | 6.25 |
ENST00000605526.1
ENST00000604062.1 ENST00000604369.1 ENST00000366185.2 ENST00000604849.1 |
RP11-258C19.5
|
long intergenic non-protein coding RNA 1155 |
| chrX_+_102883620 | 6.17 |
ENST00000372626.3
|
TCEAL1
|
transcription elongation factor A (SII)-like 1 |
| chr9_-_79307096 | 6.06 |
ENST00000376717.2
ENST00000223609.6 ENST00000443509.2 |
PRUNE2
|
prune homolog 2 (Drosophila) |
| chrX_+_118108571 | 6.01 |
ENST00000304778.7
|
LONRF3
|
LON peptidase N-terminal domain and ring finger 3 |
| chr19_-_15236173 | 5.97 |
ENST00000527093.1
|
ILVBL
|
ilvB (bacterial acetolactate synthase)-like |
| chr7_+_106685079 | 5.96 |
ENST00000265717.4
|
PRKAR2B
|
protein kinase, cAMP-dependent, regulatory, type II, beta |
| chr9_-_126030817 | 5.90 |
ENST00000348403.5
ENST00000447404.2 ENST00000360998.3 |
STRBP
|
spermatid perinuclear RNA binding protein |
| chr17_-_66951474 | 5.89 |
ENST00000269080.2
|
ABCA8
|
ATP-binding cassette, sub-family A (ABC1), member 8 |
| chr6_-_144329531 | 5.78 |
ENST00000429150.1
ENST00000392309.1 ENST00000416623.1 ENST00000392307.1 |
PLAGL1
|
pleiomorphic adenoma gene-like 1 |
| chr11_-_116968987 | 5.64 |
ENST00000434315.2
ENST00000292055.4 ENST00000375288.1 ENST00000542607.1 ENST00000445177.1 ENST00000375300.1 ENST00000446921.2 |
SIK3
|
SIK family kinase 3 |
| chr5_-_172198190 | 5.59 |
ENST00000239223.3
|
DUSP1
|
dual specificity phosphatase 1 |
| chr12_+_51632666 | 5.58 |
ENST00000604900.1
|
DAZAP2
|
DAZ associated protein 2 |
| chr11_+_18343800 | 5.48 |
ENST00000453096.2
|
GTF2H1
|
general transcription factor IIH, polypeptide 1, 62kDa |
| chr1_+_11866207 | 5.46 |
ENST00000312413.6
ENST00000346436.6 |
CLCN6
|
chloride channel, voltage-sensitive 6 |
| chrX_+_77166172 | 5.44 |
ENST00000343533.5
ENST00000350425.4 ENST00000341514.6 |
ATP7A
|
ATPase, Cu++ transporting, alpha polypeptide |
| chr5_+_122110691 | 5.32 |
ENST00000379516.2
ENST00000505934.1 ENST00000514949.1 |
SNX2
|
sorting nexin 2 |
| chrX_+_102883887 | 5.24 |
ENST00000372625.3
ENST00000372624.3 |
TCEAL1
|
transcription elongation factor A (SII)-like 1 |
| chr11_+_9595180 | 5.17 |
ENST00000450114.2
|
WEE1
|
WEE1 G2 checkpoint kinase |
| chr2_+_109204743 | 5.15 |
ENST00000332345.6
|
LIMS1
|
LIM and senescent cell antigen-like domains 1 |
| chr7_-_27196267 | 5.15 |
ENST00000242159.3
|
HOXA7
|
homeobox A7 |
| chr12_-_65153175 | 5.15 |
ENST00000543646.1
ENST00000542058.1 ENST00000258145.3 |
GNS
|
glucosamine (N-acetyl)-6-sulfatase |
| chr6_+_160390102 | 5.05 |
ENST00000356956.1
|
IGF2R
|
insulin-like growth factor 2 receptor |
| chr9_+_133978190 | 5.01 |
ENST00000372312.3
|
AIF1L
|
allograft inflammatory factor 1-like |
| chr17_-_76124711 | 4.92 |
ENST00000306591.7
ENST00000590602.1 |
TMC6
|
transmembrane channel-like 6 |
| chr20_-_45985172 | 4.83 |
ENST00000536340.1
|
ZMYND8
|
zinc finger, MYND-type containing 8 |
| chr2_-_238499303 | 4.77 |
ENST00000409576.1
|
RAB17
|
RAB17, member RAS oncogene family |
| chrX_-_34675391 | 4.70 |
ENST00000275954.3
|
TMEM47
|
transmembrane protein 47 |
| chr16_-_28503327 | 4.65 |
ENST00000535392.1
ENST00000395653.4 |
CLN3
|
ceroid-lipofuscinosis, neuronal 3 |
| chr17_-_7137857 | 4.60 |
ENST00000005340.5
|
DVL2
|
dishevelled segment polarity protein 2 |
| chr3_+_148847371 | 4.59 |
ENST00000296051.2
ENST00000460120.1 |
HPS3
|
Hermansky-Pudlak syndrome 3 |
| chr17_+_65821636 | 4.56 |
ENST00000544778.2
|
BPTF
|
bromodomain PHD finger transcription factor |
| chr16_-_28503357 | 4.52 |
ENST00000333496.9
ENST00000561505.1 ENST00000567963.1 ENST00000354630.5 ENST00000355477.5 ENST00000357076.5 ENST00000565688.1 ENST00000359984.7 |
CLN3
|
ceroid-lipofuscinosis, neuronal 3 |
| chrX_+_101975643 | 4.50 |
ENST00000361229.4
|
BHLHB9
|
basic helix-loop-helix domain containing, class B, 9 |
| chrX_+_101975619 | 4.50 |
ENST00000457056.1
|
BHLHB9
|
basic helix-loop-helix domain containing, class B, 9 |
| chr17_-_47841485 | 4.49 |
ENST00000506156.1
ENST00000240364.2 |
FAM117A
|
family with sequence similarity 117, member A |
| chr17_-_76124812 | 4.48 |
ENST00000592063.1
ENST00000589271.1 ENST00000322933.4 ENST00000589553.1 |
TMC6
|
transmembrane channel-like 6 |
| chr17_-_49337392 | 4.48 |
ENST00000376381.2
ENST00000586178.1 |
MBTD1
|
mbt domain containing 1 |
| chr17_+_65821780 | 4.40 |
ENST00000321892.4
ENST00000335221.5 ENST00000306378.6 |
BPTF
|
bromodomain PHD finger transcription factor |
| chr5_+_172483347 | 4.37 |
ENST00000522692.1
ENST00000296953.2 ENST00000540014.1 ENST00000520420.1 |
CREBRF
|
CREB3 regulatory factor |
| chr10_-_93392811 | 4.37 |
ENST00000238994.5
|
PPP1R3C
|
protein phosphatase 1, regulatory subunit 3C |
| chr6_-_33385870 | 4.36 |
ENST00000488034.1
|
CUTA
|
cutA divalent cation tolerance homolog (E. coli) |
| chr20_-_45985464 | 4.33 |
ENST00000458360.2
ENST00000262975.4 |
ZMYND8
|
zinc finger, MYND-type containing 8 |
| chr10_-_46090334 | 4.33 |
ENST00000395771.3
ENST00000319836.3 |
MARCH8
|
membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase |
| chr17_-_18266765 | 4.32 |
ENST00000354098.3
|
SHMT1
|
serine hydroxymethyltransferase 1 (soluble) |
| chr6_-_84937314 | 4.31 |
ENST00000257766.4
ENST00000403245.3 |
KIAA1009
|
KIAA1009 |
| chr7_-_100808843 | 4.24 |
ENST00000249330.2
|
VGF
|
VGF nerve growth factor inducible |
| chr20_-_45985414 | 4.23 |
ENST00000461685.1
ENST00000372023.3 ENST00000540497.1 ENST00000435836.1 ENST00000471951.2 ENST00000352431.2 ENST00000396281.4 ENST00000355972.4 ENST00000360911.3 |
ZMYND8
|
zinc finger, MYND-type containing 8 |
| chr6_-_33385823 | 4.22 |
ENST00000494751.1
ENST00000374496.3 |
CUTA
|
cutA divalent cation tolerance homolog (E. coli) |
| chr14_-_74551172 | 4.22 |
ENST00000553458.1
|
ALDH6A1
|
aldehyde dehydrogenase 6 family, member A1 |
| chr22_-_36903069 | 4.20 |
ENST00000216187.6
ENST00000423980.1 |
FOXRED2
|
FAD-dependent oxidoreductase domain containing 2 |
| chr7_-_100808394 | 4.19 |
ENST00000445482.2
|
VGF
|
VGF nerve growth factor inducible |
| chr9_-_125667618 | 4.18 |
ENST00000423239.2
|
RC3H2
|
ring finger and CCCH-type domains 2 |
| chr16_-_28503080 | 4.16 |
ENST00000565316.1
ENST00000565778.1 ENST00000357857.9 ENST00000568558.1 ENST00000357806.7 |
CLN3
|
ceroid-lipofuscinosis, neuronal 3 |
| chr16_-_15736953 | 4.11 |
ENST00000548025.1
ENST00000551742.1 ENST00000602337.1 ENST00000344181.3 ENST00000396368.3 |
KIAA0430
|
KIAA0430 |
| chr2_+_109204909 | 4.11 |
ENST00000393310.1
|
LIMS1
|
LIM and senescent cell antigen-like domains 1 |
| chr6_+_127588020 | 4.10 |
ENST00000309649.3
ENST00000610162.1 ENST00000610153.1 ENST00000608991.1 ENST00000480444.1 |
RNF146
|
ring finger protein 146 |
| chr6_-_33385854 | 4.09 |
ENST00000488478.1
|
CUTA
|
cutA divalent cation tolerance homolog (E. coli) |
| chr6_+_127587755 | 4.08 |
ENST00000368314.1
ENST00000476956.1 ENST00000609447.1 ENST00000356799.2 ENST00000477776.1 ENST00000609944.1 |
RNF146
|
ring finger protein 146 |
| chr9_-_125667494 | 4.07 |
ENST00000335387.5
ENST00000357244.2 ENST00000373665.2 |
RC3H2
|
ring finger and CCCH-type domains 2 |
| chr10_+_69644404 | 4.05 |
ENST00000212015.6
|
SIRT1
|
sirtuin 1 |
| chr6_-_33385902 | 4.05 |
ENST00000374500.5
|
CUTA
|
cutA divalent cation tolerance homolog (E. coli) |
| chr9_-_13175823 | 3.96 |
ENST00000545857.1
|
MPDZ
|
multiple PDZ domain protein |
| chr14_-_20923195 | 3.96 |
ENST00000206542.4
|
OSGEP
|
O-sialoglycoprotein endopeptidase |
| chr10_+_23728198 | 3.87 |
ENST00000376495.3
|
OTUD1
|
OTU domain containing 1 |
| chr17_-_35969409 | 3.78 |
ENST00000394378.2
ENST00000585472.1 ENST00000591288.1 ENST00000502449.2 ENST00000345615.4 ENST00000346661.4 ENST00000585689.1 ENST00000339208.6 |
SYNRG
|
synergin, gamma |
| chr4_-_76439483 | 3.78 |
ENST00000380840.2
ENST00000513257.1 ENST00000507014.1 |
RCHY1
|
ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase |
| chr3_+_32147997 | 3.71 |
ENST00000282541.5
|
GPD1L
|
glycerol-3-phosphate dehydrogenase 1-like |
| chr1_-_11865982 | 3.66 |
ENST00000418034.1
|
MTHFR
|
methylenetetrahydrofolate reductase (NAD(P)H) |
| chr4_-_186733363 | 3.58 |
ENST00000393523.2
ENST00000393528.3 ENST00000449407.2 |
SORBS2
|
sorbin and SH3 domain containing 2 |
| chr6_-_33385655 | 3.57 |
ENST00000440279.3
ENST00000607266.1 |
CUTA
|
cutA divalent cation tolerance homolog (E. coli) |
| chr8_-_124553437 | 3.56 |
ENST00000517956.1
ENST00000443022.2 |
FBXO32
|
F-box protein 32 |
| chr15_+_44084040 | 3.56 |
ENST00000249786.4
|
SERF2
|
small EDRK-rich factor 2 |
| chr12_+_2986359 | 3.47 |
ENST00000538636.1
ENST00000461997.2 ENST00000489288.2 ENST00000366285.2 ENST00000538700.1 |
RHNO1
|
RAD9-HUS1-RAD1 interacting nuclear orphan 1 |
| chr16_-_67185117 | 3.46 |
ENST00000449549.3
|
B3GNT9
|
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 |
| chr21_+_38445539 | 3.44 |
ENST00000418766.1
ENST00000450533.1 ENST00000438055.1 ENST00000355666.1 ENST00000540756.1 ENST00000399010.1 |
TTC3
|
tetratricopeptide repeat domain 3 |
| chr1_-_78149041 | 3.44 |
ENST00000414381.1
ENST00000370798.1 |
ZZZ3
|
zinc finger, ZZ-type containing 3 |
| chr8_-_80993010 | 3.40 |
ENST00000537855.1
ENST00000520527.1 ENST00000517427.1 ENST00000448733.2 ENST00000379097.3 |
TPD52
|
tumor protein D52 |
| chr2_+_177053307 | 3.37 |
ENST00000331462.4
|
HOXD1
|
homeobox D1 |
| chr3_+_158519654 | 3.35 |
ENST00000415822.2
ENST00000392813.4 ENST00000264266.8 |
MFSD1
|
major facilitator superfamily domain containing 1 |
| chr20_-_2821271 | 3.34 |
ENST00000448755.1
ENST00000360652.2 |
PCED1A
|
PC-esterase domain containing 1A |
| chr14_-_20929624 | 3.34 |
ENST00000398020.4
ENST00000250489.4 |
TMEM55B
|
transmembrane protein 55B |
| chr11_+_95523823 | 3.32 |
ENST00000538658.1
|
CEP57
|
centrosomal protein 57kDa |
| chr2_-_211036051 | 3.32 |
ENST00000418791.1
ENST00000452086.1 ENST00000281772.9 |
KANSL1L
|
KAT8 regulatory NSL complex subunit 1-like |
| chr21_-_38445470 | 3.32 |
ENST00000399098.1
|
PIGP
|
phosphatidylinositol glycan anchor biosynthesis, class P |
| chr9_-_98279241 | 3.32 |
ENST00000437951.1
ENST00000375274.2 ENST00000430669.2 ENST00000468211.2 |
PTCH1
|
patched 1 |
| chr8_-_54755459 | 3.31 |
ENST00000524234.1
ENST00000521275.1 ENST00000396774.2 |
ATP6V1H
|
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H |
| chr10_-_126849588 | 3.30 |
ENST00000411419.2
|
CTBP2
|
C-terminal binding protein 2 |
| chr4_-_16900184 | 3.27 |
ENST00000515064.1
|
LDB2
|
LIM domain binding 2 |
| chr4_-_16900410 | 3.27 |
ENST00000304523.5
|
LDB2
|
LIM domain binding 2 |
| chr11_+_63706444 | 3.26 |
ENST00000377793.4
ENST00000456907.2 ENST00000539656.1 |
NAA40
|
N(alpha)-acetyltransferase 40, NatD catalytic subunit |
| chr4_-_16900217 | 3.23 |
ENST00000441778.2
|
LDB2
|
LIM domain binding 2 |
| chr2_-_136875712 | 3.22 |
ENST00000241393.3
|
CXCR4
|
chemokine (C-X-C motif) receptor 4 |
| chr5_-_132299313 | 3.22 |
ENST00000265343.5
|
AFF4
|
AF4/FMR2 family, member 4 |
| chr4_-_16900242 | 3.22 |
ENST00000502640.1
ENST00000506732.1 |
LDB2
|
LIM domain binding 2 |
| chr11_-_57283159 | 3.22 |
ENST00000533263.1
ENST00000278426.3 |
SLC43A1
|
solute carrier family 43 (amino acid system L transporter), member 1 |
| chr1_-_52521831 | 3.21 |
ENST00000371626.4
|
TXNDC12
|
thioredoxin domain containing 12 (endoplasmic reticulum) |
| chr17_-_21156578 | 3.19 |
ENST00000399011.2
ENST00000468196.1 |
C17orf103
|
chromosome 17 open reading frame 103 |
| chr8_+_71581565 | 3.17 |
ENST00000408926.3
ENST00000520030.1 |
XKR9
|
XK, Kell blood group complex subunit-related family, member 9 |
| chr8_+_95907993 | 3.15 |
ENST00000523378.1
|
NDUFAF6
|
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 |
| chr3_-_4508925 | 3.14 |
ENST00000534863.1
ENST00000383843.5 ENST00000458465.2 ENST00000405420.2 ENST00000272902.5 |
SUMF1
|
sulfatase modifying factor 1 |
| chr11_+_59522900 | 3.13 |
ENST00000529177.1
|
STX3
|
syntaxin 3 |
| chr1_-_113498943 | 3.13 |
ENST00000369626.3
|
SLC16A1
|
solute carrier family 16 (monocarboxylate transporter), member 1 |
| chr6_+_123110465 | 3.10 |
ENST00000539041.1
|
SMPDL3A
|
sphingomyelin phosphodiesterase, acid-like 3A |
| chr1_+_10092890 | 3.10 |
ENST00000253251.8
ENST00000377157.3 |
UBE4B
|
ubiquitination factor E4B |
| chr4_+_41540160 | 3.09 |
ENST00000503057.1
ENST00000511496.1 |
LIMCH1
|
LIM and calponin homology domains 1 |
| chr14_+_61789382 | 3.09 |
ENST00000555082.1
|
PRKCH
|
protein kinase C, eta |
| chr8_-_54755789 | 3.08 |
ENST00000359530.2
|
ATP6V1H
|
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H |
| chr11_+_126081662 | 3.04 |
ENST00000528985.1
ENST00000529731.1 ENST00000360194.4 ENST00000530043.1 |
FAM118B
|
family with sequence similarity 118, member B |
| chr1_-_154531095 | 3.03 |
ENST00000292211.4
|
UBE2Q1
|
ubiquitin-conjugating enzyme E2Q family member 1 |
| chr8_-_82754427 | 3.01 |
ENST00000353788.4
ENST00000520618.1 ENST00000518183.1 ENST00000396330.2 ENST00000519119.1 ENST00000345957.4 |
SNX16
|
sorting nexin 16 |
| chr2_-_197036289 | 2.97 |
ENST00000263955.4
|
STK17B
|
serine/threonine kinase 17b |
| chr11_+_18344106 | 2.97 |
ENST00000534641.1
ENST00000525831.1 ENST00000265963.4 |
GTF2H1
|
general transcription factor IIH, polypeptide 1, 62kDa |
| chr10_-_50396407 | 2.96 |
ENST00000374153.2
ENST00000374151.3 |
C10orf128
|
chromosome 10 open reading frame 128 |
| chr7_+_155090271 | 2.96 |
ENST00000476756.1
|
INSIG1
|
insulin induced gene 1 |
| chr6_+_123110302 | 2.96 |
ENST00000368440.4
|
SMPDL3A
|
sphingomyelin phosphodiesterase, acid-like 3A |
| chr4_-_149363662 | 2.93 |
ENST00000355292.3
ENST00000358102.3 |
NR3C2
|
nuclear receptor subfamily 3, group C, member 2 |
| chr4_-_76439596 | 2.92 |
ENST00000451788.1
ENST00000512706.1 |
RCHY1
|
ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase |
| chr13_+_42846272 | 2.92 |
ENST00000025301.2
|
AKAP11
|
A kinase (PRKA) anchor protein 11 |
| chr21_-_38445297 | 2.91 |
ENST00000430792.1
ENST00000399103.1 |
PIGP
|
phosphatidylinositol glycan anchor biosynthesis, class P |
| chr16_+_2570340 | 2.90 |
ENST00000568263.1
ENST00000293971.6 ENST00000302956.4 ENST00000413459.3 ENST00000566706.1 ENST00000569879.1 |
AMDHD2
|
amidohydrolase domain containing 2 |
| chr16_-_4588469 | 2.90 |
ENST00000588381.1
ENST00000563332.2 |
CDIP1
|
cell death-inducing p53 target 1 |
| chr6_-_80657292 | 2.90 |
ENST00000369816.4
|
ELOVL4
|
ELOVL fatty acid elongase 4 |
| chr19_+_5681011 | 2.90 |
ENST00000581893.1
ENST00000411793.2 ENST00000301382.4 ENST00000581773.1 ENST00000423665.2 ENST00000583928.1 ENST00000342970.2 ENST00000422535.2 ENST00000581521.1 ENST00000339423.2 |
HSD11B1L
|
hydroxysteroid (11-beta) dehydrogenase 1-like |
| chr16_-_57219721 | 2.86 |
ENST00000562406.1
ENST00000568671.1 ENST00000567044.1 |
FAM192A
|
family with sequence similarity 192, member A |
| chr12_+_14518598 | 2.84 |
ENST00000261168.4
ENST00000538511.1 ENST00000545723.1 ENST00000543189.1 ENST00000536444.1 |
ATF7IP
|
activating transcription factor 7 interacting protein |
| chr2_+_220042933 | 2.80 |
ENST00000430297.2
|
FAM134A
|
family with sequence similarity 134, member A |
| chr5_+_43603229 | 2.77 |
ENST00000344920.4
ENST00000512996.2 |
NNT
|
nicotinamide nucleotide transhydrogenase |
| chr10_+_112327425 | 2.75 |
ENST00000361804.4
|
SMC3
|
structural maintenance of chromosomes 3 |
| chr1_-_154928562 | 2.70 |
ENST00000368463.3
ENST00000539880.1 ENST00000542459.1 ENST00000368460.3 ENST00000368465.1 |
PBXIP1
|
pre-B-cell leukemia homeobox interacting protein 1 |
| chr17_-_62915574 | 2.70 |
ENST00000339474.5
ENST00000581368.1 |
LRRC37A3
|
leucine rich repeat containing 37, member A3 |
| chr1_+_150254936 | 2.69 |
ENST00000447007.1
ENST00000369095.1 ENST00000369094.1 |
C1orf51
|
chromosome 1 open reading frame 51 |
| chr19_-_49137790 | 2.69 |
ENST00000599385.1
|
DBP
|
D site of albumin promoter (albumin D-box) binding protein |
| chr3_-_17783990 | 2.69 |
ENST00000429383.4
ENST00000446863.1 ENST00000414349.1 ENST00000428355.1 ENST00000425944.1 ENST00000445294.1 ENST00000444471.1 ENST00000415814.2 |
TBC1D5
|
TBC1 domain family, member 5 |
| chr22_-_37880543 | 2.68 |
ENST00000442496.1
|
MFNG
|
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| chr17_-_7137582 | 2.67 |
ENST00000575756.1
ENST00000575458.1 |
DVL2
|
dishevelled segment polarity protein 2 |
| chr17_+_42977122 | 2.65 |
ENST00000412523.2
ENST00000331733.4 ENST00000417826.2 |
FAM187A
CCDC103
|
family with sequence similarity 187, member A coiled-coil domain containing 103 |
| chr7_+_44646162 | 2.65 |
ENST00000439616.2
|
OGDH
|
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
| chr17_-_73975444 | 2.64 |
ENST00000293217.5
ENST00000537812.1 |
ACOX1
|
acyl-CoA oxidase 1, palmitoyl |
| chr21_-_38445011 | 2.63 |
ENST00000464265.1
ENST00000399102.1 |
PIGP
|
phosphatidylinositol glycan anchor biosynthesis, class P |
| chr5_+_41904431 | 2.63 |
ENST00000381647.2
|
C5orf51
|
chromosome 5 open reading frame 51 |
| chr9_+_125703282 | 2.62 |
ENST00000373647.4
ENST00000402311.1 |
RABGAP1
|
RAB GTPase activating protein 1 |
| chr17_-_18266797 | 2.62 |
ENST00000316694.3
ENST00000539052.1 |
SHMT1
|
serine hydroxymethyltransferase 1 (soluble) |
| chr17_-_57184260 | 2.62 |
ENST00000376149.3
ENST00000393066.3 |
TRIM37
|
tripartite motif containing 37 |
| chr21_-_38445443 | 2.59 |
ENST00000360525.4
|
PIGP
|
phosphatidylinositol glycan anchor biosynthesis, class P |
| chr22_+_40573921 | 2.57 |
ENST00000454349.2
ENST00000335727.9 |
TNRC6B
|
trinucleotide repeat containing 6B |
| chr2_+_46926326 | 2.57 |
ENST00000394861.2
|
SOCS5
|
suppressor of cytokine signaling 5 |
| chr17_-_18266660 | 2.50 |
ENST00000582653.1
ENST00000352886.6 |
SHMT1
|
serine hydroxymethyltransferase 1 (soluble) |
| chr1_+_66999268 | 2.49 |
ENST00000371039.1
ENST00000424320.1 |
SGIP1
|
SH3-domain GRB2-like (endophilin) interacting protein 1 |
| chr20_-_2821756 | 2.48 |
ENST00000356872.3
ENST00000439542.1 |
PCED1A
|
PC-esterase domain containing 1A |
| chr19_+_2476116 | 2.46 |
ENST00000215631.4
ENST00000587345.1 |
GADD45B
|
growth arrest and DNA-damage-inducible, beta |
| chr22_-_39268192 | 2.46 |
ENST00000216083.6
|
CBX6
|
chromobox homolog 6 |
| chr3_+_134204551 | 2.44 |
ENST00000332047.5
ENST00000354446.3 |
CEP63
|
centrosomal protein 63kDa |
| chr16_+_68119247 | 2.42 |
ENST00000575270.1
|
NFATC3
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
| chr14_+_64970662 | 2.42 |
ENST00000556965.1
ENST00000554015.1 |
ZBTB1
|
zinc finger and BTB domain containing 1 |
| chr4_+_39184024 | 2.42 |
ENST00000399820.3
ENST00000509560.1 ENST00000512112.1 ENST00000288634.7 ENST00000506503.1 |
WDR19
|
WD repeat domain 19 |
| chr21_-_46237883 | 2.40 |
ENST00000397893.3
|
SUMO3
|
small ubiquitin-like modifier 3 |
| chr1_+_42922173 | 2.39 |
ENST00000455780.1
ENST00000372560.3 ENST00000372561.3 ENST00000372556.3 |
PPCS
|
phosphopantothenoylcysteine synthetase |
| chr4_+_108910870 | 2.39 |
ENST00000403312.1
ENST00000603302.1 ENST00000309522.3 |
HADH
|
hydroxyacyl-CoA dehydrogenase |
| chr6_-_151773232 | 2.39 |
ENST00000444024.1
ENST00000367303.4 |
RMND1
|
required for meiotic nuclear division 1 homolog (S. cerevisiae) |
| chrX_+_10124977 | 2.39 |
ENST00000380833.4
|
CLCN4
|
chloride channel, voltage-sensitive 4 |
| chr10_+_46222648 | 2.37 |
ENST00000336378.4
ENST00000540872.1 ENST00000537517.1 ENST00000374362.2 ENST00000359860.4 ENST00000420848.1 |
FAM21C
|
family with sequence similarity 21, member C |
| chr19_+_13049413 | 2.34 |
ENST00000316448.5
ENST00000588454.1 |
CALR
|
calreticulin |
| chr4_+_108911036 | 2.34 |
ENST00000505878.1
|
HADH
|
hydroxyacyl-CoA dehydrogenase |
| chr17_+_40913210 | 2.33 |
ENST00000253796.5
|
RAMP2
|
receptor (G protein-coupled) activity modifying protein 2 |
| chr9_-_97356075 | 2.32 |
ENST00000375337.3
|
FBP2
|
fructose-1,6-bisphosphatase 2 |
| chr11_+_101981169 | 2.32 |
ENST00000526343.1
ENST00000282441.5 ENST00000537274.1 ENST00000345877.2 |
YAP1
|
Yes-associated protein 1 |
| chr8_+_74903580 | 2.32 |
ENST00000284818.2
ENST00000518893.1 |
LY96
|
lymphocyte antigen 96 |
| chr18_+_72922710 | 2.32 |
ENST00000322038.5
|
TSHZ1
|
teashirt zinc finger homeobox 1 |
| chr10_+_99258625 | 2.32 |
ENST00000370664.3
|
UBTD1
|
ubiquitin domain containing 1 |
| chr9_+_131709966 | 2.30 |
ENST00000372577.2
|
NUP188
|
nucleoporin 188kDa |
| chr10_-_64576105 | 2.30 |
ENST00000242480.3
ENST00000411732.1 |
EGR2
|
early growth response 2 |
| chr1_+_65210772 | 2.30 |
ENST00000371072.4
ENST00000294428.3 |
RAVER2
|
ribonucleoprotein, PTB-binding 2 |
| chr16_-_2097787 | 2.30 |
ENST00000566380.1
ENST00000219066.1 |
NTHL1
|
nth endonuclease III-like 1 (E. coli) |
| chr6_-_109703600 | 2.29 |
ENST00000512821.1
|
CD164
|
CD164 molecule, sialomucin |
| chr10_+_22605304 | 2.29 |
ENST00000475460.2
ENST00000602390.1 ENST00000489125.2 ENST00000456711.1 ENST00000444869.1 |
COMMD3-BMI1
COMMD3
|
COMMD3-BMI1 readthrough COMM domain containing 3 |
| chr9_-_134145880 | 2.29 |
ENST00000372269.3
ENST00000464831.1 |
FAM78A
|
family with sequence similarity 78, member A |
Network of associatons between targets according to the STRING database.
First level regulatory network of MLX_USF2_USF1_PAX2
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.5 | 13.5 | GO:0048392 | apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007) |
| 3.4 | 10.1 | GO:0051780 | mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780) |
| 3.3 | 13.3 | GO:0035752 | lysosomal lumen pH elevation(GO:0035752) |
| 3.1 | 9.4 | GO:1904481 | response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482) |
| 2.9 | 11.8 | GO:0006210 | pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859) |
| 2.5 | 19.8 | GO:0045629 | negative regulation of T-helper 2 cell differentiation(GO:0045629) |
| 2.4 | 14.6 | GO:1903756 | regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758) |
| 2.3 | 11.5 | GO:0033274 | response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829) |
| 2.3 | 6.8 | GO:0060435 | bronchiole development(GO:0060435) |
| 2.2 | 11.0 | GO:0002415 | immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415) |
| 1.8 | 7.3 | GO:0022007 | neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) |
| 1.8 | 5.4 | GO:0071284 | cellular response to lead ion(GO:0071284) |
| 1.7 | 12.1 | GO:0098967 | exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967) |
| 1.5 | 4.4 | GO:1900169 | regulation of glucocorticoid mediated signaling pathway(GO:1900169) |
| 1.4 | 13.0 | GO:1990253 | cellular response to leucine starvation(GO:1990253) |
| 1.4 | 9.6 | GO:0034316 | negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) |
| 1.4 | 4.1 | GO:0051097 | negative regulation of helicase activity(GO:0051097) |
| 1.3 | 4.0 | GO:0002949 | tRNA threonylcarbamoyladenosine modification(GO:0002949) |
| 1.3 | 4.0 | GO:1905205 | positive regulation of connective tissue replacement(GO:1905205) |
| 1.3 | 5.3 | GO:0010157 | response to chlorate(GO:0010157) |
| 1.3 | 9.2 | GO:1902231 | positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231) |
| 1.3 | 7.8 | GO:0060399 | positive regulation of growth hormone receptor signaling pathway(GO:0060399) |
| 1.2 | 5.9 | GO:0061034 | olfactory bulb mitral cell layer development(GO:0061034) |
| 1.0 | 4.1 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
| 1.0 | 6.0 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
| 1.0 | 3.0 | GO:0036353 | histone H2A-K119 monoubiquitination(GO:0036353) |
| 1.0 | 3.0 | GO:1901301 | regulation of cargo loading into COPII-coated vesicle(GO:1901301) |
| 0.9 | 3.7 | GO:0090038 | negative regulation of protein kinase C signaling(GO:0090038) |
| 0.9 | 4.6 | GO:0006740 | NADPH regeneration(GO:0006740) |
| 0.9 | 11.6 | GO:0001766 | membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) |
| 0.9 | 3.5 | GO:0070318 | positive regulation of G0 to G1 transition(GO:0070318) |
| 0.9 | 6.0 | GO:0097338 | response to clozapine(GO:0097338) |
| 0.8 | 2.5 | GO:0032707 | negative regulation of interleukin-23 production(GO:0032707) |
| 0.8 | 7.3 | GO:0061470 | T follicular helper cell differentiation(GO:0061470) |
| 0.8 | 2.4 | GO:1900073 | regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075) |
| 0.8 | 5.7 | GO:0098535 | de novo centriole assembly(GO:0098535) |
| 0.8 | 2.4 | GO:0035284 | rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284) |
| 0.8 | 3.8 | GO:1905098 | negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098) |
| 0.8 | 3.0 | GO:0097010 | eukaryotic translation initiation factor 4F complex assembly(GO:0097010) |
| 0.7 | 13.5 | GO:0040015 | negative regulation of multicellular organism growth(GO:0040015) |
| 0.7 | 2.2 | GO:0071557 | histone H3-K27 demethylation(GO:0071557) |
| 0.7 | 6.5 | GO:0097646 | calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647) |
| 0.7 | 2.1 | GO:1903028 | positive regulation of opsonization(GO:1903028) |
| 0.7 | 4.7 | GO:0044800 | fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800) |
| 0.7 | 2.0 | GO:0046709 | IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709) |
| 0.7 | 2.0 | GO:1902683 | regulation of receptor localization to synapse(GO:1902683) |
| 0.6 | 1.3 | GO:0060995 | cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) |
| 0.6 | 1.9 | GO:0002384 | hepatic immune response(GO:0002384) |
| 0.6 | 2.5 | GO:0060830 | ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) |
| 0.6 | 2.4 | GO:0002572 | pro-T cell differentiation(GO:0002572) |
| 0.6 | 1.2 | GO:0006425 | glutaminyl-tRNA aminoacylation(GO:0006425) |
| 0.6 | 2.3 | GO:0005986 | sucrose biosynthetic process(GO:0005986) |
| 0.6 | 4.1 | GO:1901314 | negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) |
| 0.6 | 2.9 | GO:0071506 | response to mycophenolic acid(GO:0071505) cellular response to mycophenolic acid(GO:0071506) |
| 0.6 | 2.3 | GO:0061357 | positive regulation of Wnt protein secretion(GO:0061357) |
| 0.6 | 1.7 | GO:0072720 | response to dithiothreitol(GO:0072720) |
| 0.5 | 10.3 | GO:0042340 | keratan sulfate catabolic process(GO:0042340) |
| 0.5 | 2.1 | GO:1901842 | negative regulation of high voltage-gated calcium channel activity(GO:1901842) |
| 0.5 | 1.6 | GO:0051596 | methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727) |
| 0.5 | 6.1 | GO:0034058 | endosomal vesicle fusion(GO:0034058) |
| 0.5 | 12.1 | GO:0016254 | preassembly of GPI anchor in ER membrane(GO:0016254) |
| 0.5 | 2.0 | GO:1904327 | protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379) |
| 0.5 | 5.9 | GO:0042908 | xenobiotic transport(GO:0042908) |
| 0.5 | 1.5 | GO:1904760 | myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760) |
| 0.5 | 6.1 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
| 0.5 | 2.3 | GO:0032497 | detection of lipopolysaccharide(GO:0032497) |
| 0.5 | 2.3 | GO:0060023 | soft palate development(GO:0060023) |
| 0.5 | 1.8 | GO:0046452 | dihydrofolate metabolic process(GO:0046452) |
| 0.5 | 2.7 | GO:0019262 | N-acetylneuraminate catabolic process(GO:0019262) |
| 0.5 | 14.1 | GO:0010669 | epithelial structure maintenance(GO:0010669) |
| 0.5 | 0.9 | GO:0005985 | sucrose metabolic process(GO:0005985) |
| 0.5 | 1.8 | GO:0051088 | PMA-inducible membrane protein ectodomain proteolysis(GO:0051088) |
| 0.5 | 1.4 | GO:0006864 | pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519) |
| 0.4 | 0.9 | GO:0006290 | pyrimidine dimer repair(GO:0006290) |
| 0.4 | 3.1 | GO:0034350 | regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351) |
| 0.4 | 0.9 | GO:1900126 | negative regulation of hyaluronan biosynthetic process(GO:1900126) |
| 0.4 | 1.7 | GO:0002316 | follicular B cell differentiation(GO:0002316) |
| 0.4 | 2.2 | GO:0032474 | otolith morphogenesis(GO:0032474) |
| 0.4 | 3.9 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
| 0.4 | 5.2 | GO:0045617 | negative regulation of keratinocyte differentiation(GO:0045617) |
| 0.4 | 1.3 | GO:0048633 | positive regulation of skeletal muscle tissue growth(GO:0048633) |
| 0.4 | 11.1 | GO:0002021 | response to dietary excess(GO:0002021) |
| 0.4 | 1.7 | GO:0060010 | Sertoli cell fate commitment(GO:0060010) |
| 0.4 | 2.1 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
| 0.4 | 1.2 | GO:2000854 | positive regulation of corticosterone secretion(GO:2000854) |
| 0.4 | 1.2 | GO:0044313 | protein K6-linked deubiquitination(GO:0044313) |
| 0.4 | 3.6 | GO:0045716 | positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716) |
| 0.4 | 4.3 | GO:0070459 | prolactin secretion(GO:0070459) |
| 0.4 | 1.2 | GO:0033364 | mast cell secretory granule organization(GO:0033364) |
| 0.4 | 2.3 | GO:0002501 | peptide antigen assembly with MHC protein complex(GO:0002501) |
| 0.4 | 10.8 | GO:0090190 | positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190) |
| 0.4 | 1.2 | GO:1903674 | regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676) |
| 0.4 | 2.6 | GO:0044789 | modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791) |
| 0.4 | 1.1 | GO:0002276 | basophil activation involved in immune response(GO:0002276) |
| 0.4 | 2.2 | GO:0061113 | pancreas morphogenesis(GO:0061113) |
| 0.4 | 2.2 | GO:0006041 | glucosamine metabolic process(GO:0006041) |
| 0.4 | 7.1 | GO:0071850 | mitotic cell cycle arrest(GO:0071850) |
| 0.4 | 6.5 | GO:0072189 | ureter development(GO:0072189) |
| 0.4 | 1.8 | GO:0018364 | peptidyl-glutamine methylation(GO:0018364) |
| 0.4 | 8.6 | GO:0070816 | phosphorylation of RNA polymerase II C-terminal domain(GO:0070816) |
| 0.3 | 1.0 | GO:0061582 | intestinal epithelial cell migration(GO:0061582) |
| 0.3 | 2.1 | GO:0060754 | positive regulation of mast cell chemotaxis(GO:0060754) |
| 0.3 | 2.1 | GO:0016480 | negative regulation of transcription from RNA polymerase III promoter(GO:0016480) |
| 0.3 | 1.4 | GO:0043504 | mitochondrial DNA repair(GO:0043504) |
| 0.3 | 2.3 | GO:1902459 | positive regulation of stem cell population maintenance(GO:1902459) |
| 0.3 | 1.3 | GO:0043335 | protein unfolding(GO:0043335) |
| 0.3 | 2.3 | GO:0006296 | nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296) |
| 0.3 | 1.3 | GO:0042823 | pyridoxal phosphate biosynthetic process(GO:0042823) |
| 0.3 | 3.6 | GO:0014894 | response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
| 0.3 | 1.3 | GO:0033123 | positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123) |
| 0.3 | 2.2 | GO:2000286 | receptor internalization involved in canonical Wnt signaling pathway(GO:2000286) |
| 0.3 | 1.0 | GO:0050787 | detoxification of mercury ion(GO:0050787) |
| 0.3 | 0.9 | GO:0090310 | negative regulation of methylation-dependent chromatin silencing(GO:0090310) |
| 0.3 | 0.3 | GO:2000506 | negative regulation of energy homeostasis(GO:2000506) |
| 0.3 | 2.5 | GO:0036444 | calcium ion transmembrane import into mitochondrion(GO:0036444) |
| 0.3 | 1.8 | GO:0036111 | very long-chain fatty-acyl-CoA metabolic process(GO:0036111) |
| 0.3 | 2.1 | GO:1903232 | melanosome assembly(GO:1903232) |
| 0.3 | 3.0 | GO:2000271 | positive regulation of fibroblast apoptotic process(GO:2000271) |
| 0.3 | 0.6 | GO:0034059 | response to anoxia(GO:0034059) |
| 0.3 | 1.8 | GO:0010746 | regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) |
| 0.3 | 1.2 | GO:0035509 | negative regulation of myosin-light-chain-phosphatase activity(GO:0035509) negative regulation of bicellular tight junction assembly(GO:1903347) |
| 0.3 | 2.6 | GO:0019367 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.3 | 1.7 | GO:0044339 | canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339) |
| 0.3 | 1.7 | GO:0033132 | negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300) |
| 0.3 | 0.8 | GO:0072425 | signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434) telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884) |
| 0.3 | 0.8 | GO:0006286 | base-excision repair, base-free sugar-phosphate removal(GO:0006286) |
| 0.3 | 0.8 | GO:0035494 | SNARE complex disassembly(GO:0035494) |
| 0.3 | 1.1 | GO:1900063 | regulation of peroxisome organization(GO:1900063) |
| 0.3 | 8.8 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
| 0.3 | 1.3 | GO:0032525 | somite rostral/caudal axis specification(GO:0032525) |
| 0.3 | 2.3 | GO:0090646 | mitochondrial tRNA processing(GO:0090646) |
| 0.3 | 4.0 | GO:1902894 | negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894) |
| 0.3 | 0.8 | GO:0060723 | spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723) |
| 0.2 | 2.4 | GO:0070131 | positive regulation of mitochondrial translation(GO:0070131) |
| 0.2 | 0.7 | GO:0006059 | hexitol metabolic process(GO:0006059) |
| 0.2 | 2.6 | GO:0036109 | alpha-linolenic acid metabolic process(GO:0036109) |
| 0.2 | 1.4 | GO:0090219 | negative regulation of lipid kinase activity(GO:0090219) |
| 0.2 | 1.9 | GO:0034036 | purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428) |
| 0.2 | 1.9 | GO:0022027 | interkinetic nuclear migration(GO:0022027) |
| 0.2 | 0.5 | GO:1903553 | positive regulation of extracellular exosome assembly(GO:1903553) |
| 0.2 | 1.8 | GO:0021615 | glossopharyngeal nerve morphogenesis(GO:0021615) |
| 0.2 | 0.7 | GO:0048203 | vesicle targeting, trans-Golgi to endosome(GO:0048203) |
| 0.2 | 0.7 | GO:0034085 | establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922) negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930) |
| 0.2 | 0.9 | GO:0033512 | L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512) |
| 0.2 | 0.9 | GO:0070602 | regulation of centromeric sister chromatid cohesion(GO:0070602) |
| 0.2 | 1.8 | GO:1990034 | cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034) |
| 0.2 | 1.1 | GO:0046477 | glycosylceramide catabolic process(GO:0046477) |
| 0.2 | 2.8 | GO:0006782 | protoporphyrinogen IX biosynthetic process(GO:0006782) |
| 0.2 | 1.1 | GO:0014886 | transition between slow and fast fiber(GO:0014886) |
| 0.2 | 0.9 | GO:0015917 | aminophospholipid transport(GO:0015917) |
| 0.2 | 1.5 | GO:2000124 | regulation of endocannabinoid signaling pathway(GO:2000124) |
| 0.2 | 1.9 | GO:0051451 | myoblast migration(GO:0051451) |
| 0.2 | 0.8 | GO:1903660 | negative regulation of complement-dependent cytotoxicity(GO:1903660) |
| 0.2 | 2.1 | GO:0010499 | proteasomal ubiquitin-independent protein catabolic process(GO:0010499) |
| 0.2 | 6.5 | GO:0070987 | error-free translesion synthesis(GO:0070987) |
| 0.2 | 2.1 | GO:0035583 | sequestering of TGFbeta in extracellular matrix(GO:0035583) |
| 0.2 | 0.4 | GO:1904020 | regulation of G-protein coupled receptor internalization(GO:1904020) |
| 0.2 | 1.2 | GO:2000909 | regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909) |
| 0.2 | 1.0 | GO:0046668 | regulation of retinal cell programmed cell death(GO:0046668) |
| 0.2 | 0.6 | GO:0048200 | COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205) |
| 0.2 | 1.0 | GO:0036369 | transcription factor catabolic process(GO:0036369) |
| 0.2 | 2.0 | GO:1904936 | cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936) |
| 0.2 | 2.8 | GO:0060272 | embryonic skeletal joint morphogenesis(GO:0060272) |
| 0.2 | 3.3 | GO:0043517 | positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) |
| 0.2 | 0.8 | GO:0061763 | multivesicular body-lysosome fusion(GO:0061763) |
| 0.2 | 1.0 | GO:1902904 | negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764) |
| 0.2 | 0.8 | GO:0060748 | tertiary branching involved in mammary gland duct morphogenesis(GO:0060748) |
| 0.2 | 0.8 | GO:0000711 | meiotic DNA repair synthesis(GO:0000711) |
| 0.2 | 2.1 | GO:0010739 | positive regulation of protein kinase A signaling(GO:0010739) |
| 0.2 | 3.0 | GO:0030043 | actin filament fragmentation(GO:0030043) |
| 0.2 | 1.1 | GO:2000664 | positive regulation of interleukin-5 secretion(GO:2000664) |
| 0.2 | 1.5 | GO:0061469 | regulation of type B pancreatic cell proliferation(GO:0061469) |
| 0.2 | 3.0 | GO:0030575 | nuclear body organization(GO:0030575) |
| 0.2 | 6.6 | GO:0070911 | global genome nucleotide-excision repair(GO:0070911) |
| 0.2 | 4.2 | GO:0018027 | peptidyl-lysine dimethylation(GO:0018027) |
| 0.2 | 3.1 | GO:0060213 | regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) |
| 0.2 | 2.1 | GO:0042118 | endothelial cell activation(GO:0042118) |
| 0.2 | 5.3 | GO:0051894 | positive regulation of focal adhesion assembly(GO:0051894) |
| 0.2 | 3.2 | GO:1902236 | negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236) |
| 0.2 | 5.2 | GO:0007638 | mechanosensory behavior(GO:0007638) |
| 0.2 | 2.2 | GO:0000722 | telomere maintenance via recombination(GO:0000722) |
| 0.2 | 1.3 | GO:2000507 | positive regulation of energy homeostasis(GO:2000507) |
| 0.2 | 2.0 | GO:0051135 | positive regulation of NK T cell activation(GO:0051135) |
| 0.2 | 2.3 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 0.2 | 0.3 | GO:0070054 | mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response(GO:0030969) mRNA splicing, via endonucleolytic cleavage and ligation(GO:0070054) mRNA endonucleolytic cleavage involved in unfolded protein response(GO:0070055) |
| 0.2 | 2.1 | GO:0060009 | Sertoli cell development(GO:0060009) |
| 0.2 | 2.2 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
| 0.2 | 0.6 | GO:0051083 | 'de novo' cotranslational protein folding(GO:0051083) |
| 0.1 | 2.4 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
| 0.1 | 2.4 | GO:0045475 | locomotor rhythm(GO:0045475) |
| 0.1 | 1.6 | GO:0044341 | sodium-dependent phosphate transport(GO:0044341) |
| 0.1 | 14.3 | GO:0030433 | ER-associated ubiquitin-dependent protein catabolic process(GO:0030433) |
| 0.1 | 0.9 | GO:0060744 | thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744) |
| 0.1 | 1.0 | GO:0071907 | determination of digestive tract left/right asymmetry(GO:0071907) |
| 0.1 | 0.4 | GO:0036371 | protein localization to T-tubule(GO:0036371) |
| 0.1 | 2.9 | GO:0045898 | regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) |
| 0.1 | 1.2 | GO:0006489 | dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465) |
| 0.1 | 2.1 | GO:0050765 | negative regulation of phagocytosis(GO:0050765) |
| 0.1 | 0.8 | GO:2000323 | negative regulation of glucocorticoid receptor signaling pathway(GO:2000323) |
| 0.1 | 7.4 | GO:1990090 | cellular response to nerve growth factor stimulus(GO:1990090) |
| 0.1 | 6.9 | GO:0050690 | regulation of defense response to virus by virus(GO:0050690) |
| 0.1 | 1.3 | GO:0015886 | heme transport(GO:0015886) |
| 0.1 | 2.8 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
| 0.1 | 0.4 | GO:0007538 | primary sex determination(GO:0007538) |
| 0.1 | 0.5 | GO:0032490 | detection of molecule of bacterial origin(GO:0032490) |
| 0.1 | 7.1 | GO:0007223 | Wnt signaling pathway, calcium modulating pathway(GO:0007223) |
| 0.1 | 1.8 | GO:0006975 | DNA damage induced protein phosphorylation(GO:0006975) |
| 0.1 | 2.1 | GO:0006677 | glycosylceramide metabolic process(GO:0006677) |
| 0.1 | 2.7 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 0.1 | 1.1 | GO:0070236 | negative regulation of activation-induced cell death of T cells(GO:0070236) |
| 0.1 | 3.9 | GO:0070936 | protein K48-linked ubiquitination(GO:0070936) |
| 0.1 | 1.5 | GO:0061318 | renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) |
| 0.1 | 0.1 | GO:1903094 | regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157) |
| 0.1 | 0.3 | GO:0044205 | 'de novo' UMP biosynthetic process(GO:0044205) |
| 0.1 | 1.7 | GO:0035360 | positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360) |
| 0.1 | 0.8 | GO:0030242 | pexophagy(GO:0030242) |
| 0.1 | 0.4 | GO:0060265 | positive regulation of respiratory burst involved in inflammatory response(GO:0060265) |
| 0.1 | 3.3 | GO:0046856 | phosphatidylinositol dephosphorylation(GO:0046856) |
| 0.1 | 0.3 | GO:1902960 | regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246) |
| 0.1 | 3.3 | GO:0034453 | microtubule anchoring(GO:0034453) |
| 0.1 | 0.6 | GO:0071163 | DNA replication preinitiation complex assembly(GO:0071163) |
| 0.1 | 0.5 | GO:0016240 | autophagosome docking(GO:0016240) |
| 0.1 | 6.7 | GO:0051865 | protein autoubiquitination(GO:0051865) |
| 0.1 | 0.4 | GO:0090238 | positive regulation of arachidonic acid secretion(GO:0090238) |
| 0.1 | 1.4 | GO:0060766 | negative regulation of androgen receptor signaling pathway(GO:0060766) |
| 0.1 | 9.6 | GO:0032981 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
| 0.1 | 0.3 | GO:0016256 | N-glycan processing to lysosome(GO:0016256) |
| 0.1 | 0.5 | GO:0033490 | cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490) |
| 0.1 | 0.9 | GO:0032286 | central nervous system myelin maintenance(GO:0032286) |
| 0.1 | 0.7 | GO:0080009 | mRNA methylation(GO:0080009) |
| 0.1 | 3.6 | GO:0046676 | negative regulation of insulin secretion(GO:0046676) |
| 0.1 | 1.6 | GO:0097034 | mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034) |
| 0.1 | 0.1 | GO:0007442 | hindgut morphogenesis(GO:0007442) embryonic hindgut morphogenesis(GO:0048619) |
| 0.1 | 3.2 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.1 | 0.3 | GO:0019417 | sulfur oxidation(GO:0019417) |
| 0.1 | 0.3 | GO:0006434 | seryl-tRNA aminoacylation(GO:0006434) |
| 0.1 | 0.5 | GO:0015862 | uridine transport(GO:0015862) |
| 0.1 | 0.3 | GO:0010936 | negative regulation of macrophage cytokine production(GO:0010936) |
| 0.1 | 1.0 | GO:0061462 | protein localization to lysosome(GO:0061462) |
| 0.1 | 1.6 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
| 0.1 | 0.4 | GO:0033484 | nitric oxide homeostasis(GO:0033484) |
| 0.1 | 8.8 | GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) |
| 0.1 | 2.1 | GO:0045725 | positive regulation of glycogen biosynthetic process(GO:0045725) |
| 0.1 | 1.0 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
| 0.1 | 3.6 | GO:0009250 | glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250) |
| 0.1 | 0.4 | GO:0031296 | B cell costimulation(GO:0031296) |
| 0.1 | 1.6 | GO:0032836 | glomerular basement membrane development(GO:0032836) |
| 0.1 | 0.6 | GO:0008343 | adult feeding behavior(GO:0008343) |
| 0.1 | 1.8 | GO:0031293 | membrane protein intracellular domain proteolysis(GO:0031293) |
| 0.1 | 0.7 | GO:0006572 | tyrosine catabolic process(GO:0006572) |
| 0.1 | 0.9 | GO:0071285 | cellular response to lithium ion(GO:0071285) |
| 0.1 | 0.7 | GO:0035845 | photoreceptor cell outer segment organization(GO:0035845) |
| 0.1 | 1.2 | GO:0046951 | ketone body biosynthetic process(GO:0046951) |
| 0.1 | 0.9 | GO:0045064 | T-helper 2 cell differentiation(GO:0045064) |
| 0.1 | 2.5 | GO:0002092 | positive regulation of receptor internalization(GO:0002092) |
| 0.1 | 0.2 | GO:0035606 | induction of programmed cell death(GO:0012502) peptidyl-cysteine S-trans-nitrosylation(GO:0035606) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501) |
| 0.1 | 1.1 | GO:0051770 | positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770) |
| 0.1 | 0.2 | GO:0072137 | condensed mesenchymal cell proliferation(GO:0072137) |
| 0.1 | 1.0 | GO:0018206 | peptidyl-methionine modification(GO:0018206) |
| 0.1 | 0.2 | GO:2001245 | regulation of phosphatidylcholine biosynthetic process(GO:2001245) |
| 0.1 | 1.1 | GO:0097094 | craniofacial suture morphogenesis(GO:0097094) |
| 0.1 | 2.6 | GO:0045747 | positive regulation of Notch signaling pathway(GO:0045747) |
| 0.1 | 0.7 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
| 0.1 | 0.3 | GO:0006663 | platelet activating factor biosynthetic process(GO:0006663) |
| 0.1 | 0.2 | GO:0018057 | peptidyl-lysine oxidation(GO:0018057) |
| 0.1 | 1.7 | GO:0003298 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.1 | 3.1 | GO:0048009 | insulin-like growth factor receptor signaling pathway(GO:0048009) |
| 0.1 | 0.6 | GO:0031087 | deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087) |
| 0.1 | 0.5 | GO:0051085 | chaperone mediated protein folding requiring cofactor(GO:0051085) |
| 0.1 | 1.1 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.1 | 1.5 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
| 0.1 | 0.4 | GO:0032914 | positive regulation of transforming growth factor beta1 production(GO:0032914) |
| 0.1 | 0.1 | GO:0016340 | calcium-dependent cell-matrix adhesion(GO:0016340) |
| 0.1 | 1.4 | GO:0042753 | positive regulation of circadian rhythm(GO:0042753) |
| 0.1 | 0.3 | GO:0061624 | fructose catabolic process(GO:0006001) response to sucrose(GO:0009744) response to disaccharide(GO:0034285) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) |
| 0.1 | 0.2 | GO:0060509 | Type I pneumocyte differentiation(GO:0060509) |
| 0.1 | 3.0 | GO:1902475 | L-alpha-amino acid transmembrane transport(GO:1902475) |
| 0.1 | 3.1 | GO:1903959 | regulation of anion transmembrane transport(GO:1903959) |
| 0.1 | 0.3 | GO:0090116 | C-5 methylation of cytosine(GO:0090116) |
| 0.1 | 0.2 | GO:0006154 | adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103) |
| 0.1 | 1.6 | GO:0051123 | RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) |
| 0.1 | 0.6 | GO:0001731 | formation of translation preinitiation complex(GO:0001731) |
| 0.1 | 0.2 | GO:0035553 | oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553) |
| 0.1 | 1.5 | GO:0007216 | G-protein coupled glutamate receptor signaling pathway(GO:0007216) |
| 0.1 | 1.4 | GO:0032786 | positive regulation of DNA-templated transcription, elongation(GO:0032786) |
| 0.1 | 0.4 | GO:1904491 | protein localization to ciliary transition zone(GO:1904491) |
| 0.1 | 0.5 | GO:0042797 | 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797) |
| 0.1 | 0.7 | GO:0007379 | segment specification(GO:0007379) |
| 0.1 | 0.4 | GO:0015798 | myo-inositol transport(GO:0015798) |
| 0.1 | 0.6 | GO:0016584 | nucleosome positioning(GO:0016584) |
| 0.1 | 0.1 | GO:0034163 | regulation of toll-like receptor 9 signaling pathway(GO:0034163) |
| 0.1 | 0.5 | GO:0032264 | IMP salvage(GO:0032264) |
| 0.1 | 0.5 | GO:0071397 | cellular response to cholesterol(GO:0071397) |
| 0.1 | 1.9 | GO:0048713 | regulation of oligodendrocyte differentiation(GO:0048713) |
| 0.1 | 0.2 | GO:1904885 | beta-catenin destruction complex assembly(GO:1904885) |
| 0.1 | 0.1 | GO:0015712 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
| 0.1 | 2.8 | GO:0006409 | tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431) |
| 0.1 | 0.9 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.1 | 0.8 | GO:0001682 | tRNA 5'-leader removal(GO:0001682) |
| 0.1 | 0.8 | GO:0016446 | somatic hypermutation of immunoglobulin genes(GO:0016446) |
| 0.1 | 0.3 | GO:0019464 | glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464) |
| 0.1 | 1.8 | GO:0043928 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928) |
| 0.1 | 0.2 | GO:0032229 | negative regulation of synaptic transmission, GABAergic(GO:0032229) |
| 0.1 | 0.6 | GO:0046415 | urate metabolic process(GO:0046415) |
| 0.1 | 1.6 | GO:0006111 | regulation of gluconeogenesis(GO:0006111) |
| 0.1 | 0.9 | GO:0036295 | cellular response to increased oxygen levels(GO:0036295) |
| 0.1 | 0.3 | GO:0035822 | gene conversion(GO:0035822) |
| 0.1 | 0.4 | GO:0071569 | protein ufmylation(GO:0071569) |
| 0.1 | 2.8 | GO:0050885 | neuromuscular process controlling balance(GO:0050885) |
| 0.1 | 0.7 | GO:0038003 | opioid receptor signaling pathway(GO:0038003) |
| 0.1 | 0.3 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
| 0.1 | 0.3 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
| 0.0 | 0.4 | GO:0005984 | disaccharide metabolic process(GO:0005984) |
| 0.0 | 0.2 | GO:0090435 | protein localization to nuclear envelope(GO:0090435) |
| 0.0 | 1.8 | GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289) |
| 0.0 | 0.0 | GO:1902954 | regulation of early endosome to recycling endosome transport(GO:1902954) |
| 0.0 | 1.5 | GO:0051923 | sulfation(GO:0051923) |
| 0.0 | 0.5 | GO:0006335 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.0 | 0.1 | GO:1990834 | response to odorant(GO:1990834) |
| 0.0 | 0.7 | GO:0034638 | phosphatidylcholine catabolic process(GO:0034638) |
| 0.0 | 0.8 | GO:1900363 | regulation of mRNA polyadenylation(GO:1900363) |
| 0.0 | 0.1 | GO:0072429 | response to intra-S DNA damage checkpoint signaling(GO:0072429) |
| 0.0 | 0.3 | GO:1902222 | L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222) |
| 0.0 | 2.0 | GO:0046513 | ceramide biosynthetic process(GO:0046513) |
| 0.0 | 0.5 | GO:0061635 | regulation of protein complex stability(GO:0061635) |
| 0.0 | 0.1 | GO:0032377 | regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383) |
| 0.0 | 1.0 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
| 0.0 | 1.5 | GO:1904837 | beta-catenin-TCF complex assembly(GO:1904837) |
| 0.0 | 1.1 | GO:0006491 | N-glycan processing(GO:0006491) |
| 0.0 | 0.3 | GO:0040032 | post-embryonic body morphogenesis(GO:0040032) |
| 0.0 | 1.0 | GO:0006744 | ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663) |
| 0.0 | 2.2 | GO:0061028 | establishment of endothelial barrier(GO:0061028) |
| 0.0 | 0.1 | GO:1904354 | negative regulation of telomere capping(GO:1904354) |
| 0.0 | 0.2 | GO:0045872 | positive regulation of rhodopsin gene expression(GO:0045872) |
| 0.0 | 2.5 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
| 0.0 | 0.7 | GO:0014029 | neural crest formation(GO:0014029) |
| 0.0 | 0.0 | GO:0007079 | mitotic chromosome movement towards spindle pole(GO:0007079) |
| 0.0 | 2.0 | GO:0031122 | cytoplasmic microtubule organization(GO:0031122) |
| 0.0 | 0.6 | GO:0007097 | nuclear migration(GO:0007097) |
| 0.0 | 0.3 | GO:0099612 | protein localization to axon(GO:0099612) |
| 0.0 | 0.3 | GO:0032815 | negative regulation of natural killer cell activation(GO:0032815) |
| 0.0 | 0.0 | GO:0021502 | neural fold elevation formation(GO:0021502) positive regulation of chemokine-mediated signaling pathway(GO:0070101) |
| 0.0 | 0.2 | GO:0086053 | AV node cell to bundle of His cell communication by electrical coupling(GO:0086053) |
| 0.0 | 0.2 | GO:0045065 | cytotoxic T cell differentiation(GO:0045065) |
| 0.0 | 1.8 | GO:1901222 | regulation of NIK/NF-kappaB signaling(GO:1901222) |
| 0.0 | 0.7 | GO:0003094 | glomerular filtration(GO:0003094) |
| 0.0 | 0.8 | GO:2000144 | positive regulation of DNA-templated transcription, initiation(GO:2000144) |
| 0.0 | 0.8 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 0.0 | 0.3 | GO:0044375 | regulation of peroxisome size(GO:0044375) |
| 0.0 | 0.8 | GO:0014912 | negative regulation of smooth muscle cell migration(GO:0014912) |
| 0.0 | 0.4 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
| 0.0 | 0.3 | GO:0042276 | error-prone translesion synthesis(GO:0042276) |
| 0.0 | 0.9 | GO:0006110 | regulation of glycolytic process(GO:0006110) |
| 0.0 | 0.2 | GO:0070980 | biphenyl catabolic process(GO:0070980) |
| 0.0 | 0.4 | GO:1904778 | regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
| 0.0 | 0.5 | GO:0043562 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
| 0.0 | 0.2 | GO:1902570 | protein localization to nucleolus(GO:1902570) |
| 0.0 | 0.8 | GO:0045672 | positive regulation of osteoclast differentiation(GO:0045672) |
| 0.0 | 0.2 | GO:0008582 | regulation of synaptic growth at neuromuscular junction(GO:0008582) |
| 0.0 | 0.4 | GO:0070233 | negative regulation of T cell apoptotic process(GO:0070233) |
| 0.0 | 0.7 | GO:1990001 | inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001) |
| 0.0 | 0.8 | GO:0097178 | ruffle assembly(GO:0097178) |
| 0.0 | 0.8 | GO:1904031 | positive regulation of cyclin-dependent protein kinase activity(GO:1904031) |
| 0.0 | 0.4 | GO:2000114 | regulation of establishment of cell polarity(GO:2000114) |
| 0.0 | 0.2 | GO:0019532 | oxalate transport(GO:0019532) |
| 0.0 | 0.4 | GO:0044351 | macropinocytosis(GO:0044351) |
| 0.0 | 1.4 | GO:0014066 | regulation of phosphatidylinositol 3-kinase signaling(GO:0014066) |
| 0.0 | 0.1 | GO:0051106 | positive regulation of DNA ligation(GO:0051106) |
| 0.0 | 0.4 | GO:0003215 | cardiac right ventricle morphogenesis(GO:0003215) |
| 0.0 | 0.5 | GO:0002089 | lens morphogenesis in camera-type eye(GO:0002089) |
| 0.0 | 0.1 | GO:0045347 | negative regulation of MHC class II biosynthetic process(GO:0045347) |
| 0.0 | 3.5 | GO:0090630 | activation of GTPase activity(GO:0090630) |
| 0.0 | 0.2 | GO:2000601 | positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601) |
| 0.0 | 1.0 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.0 | 0.3 | GO:0060219 | camera-type eye photoreceptor cell differentiation(GO:0060219) |
| 0.0 | 0.2 | GO:0060736 | prostate gland growth(GO:0060736) |
| 0.0 | 0.1 | GO:0002337 | B-1 B cell differentiation(GO:0001923) B-1a B cell differentiation(GO:0002337) |
| 0.0 | 0.3 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 0.0 | 0.1 | GO:0045903 | positive regulation of translational fidelity(GO:0045903) |
| 0.0 | 0.5 | GO:0001502 | cartilage condensation(GO:0001502) |
| 0.0 | 0.7 | GO:1904659 | hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659) |
| 0.0 | 0.2 | GO:0006907 | pinocytosis(GO:0006907) |
| 0.0 | 0.3 | GO:0006553 | lysine metabolic process(GO:0006553) |
| 0.0 | 0.5 | GO:0051601 | exocyst localization(GO:0051601) |
| 0.0 | 1.0 | GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771) |
| 0.0 | 0.2 | GO:0051151 | negative regulation of smooth muscle cell differentiation(GO:0051151) |
| 0.0 | 4.2 | GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184) |
| 0.0 | 0.1 | GO:0039506 | modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148) |
| 0.0 | 3.4 | GO:0007286 | spermatid development(GO:0007286) |
| 0.0 | 0.2 | GO:0070973 | protein localization to endoplasmic reticulum exit site(GO:0070973) |
| 0.0 | 1.9 | GO:0048207 | vesicle coating(GO:0006901) vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) |
| 0.0 | 3.2 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 0.0 | 0.4 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
| 0.0 | 0.2 | GO:1902741 | interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741) |
| 0.0 | 1.4 | GO:0006968 | cellular defense response(GO:0006968) |
| 0.0 | 0.1 | GO:1901029 | negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029) |
| 0.0 | 0.6 | GO:0048246 | macrophage chemotaxis(GO:0048246) |
| 0.0 | 2.4 | GO:0008643 | carbohydrate transport(GO:0008643) |
| 0.0 | 0.3 | GO:0051964 | netrin-activated signaling pathway(GO:0038007) negative regulation of synapse assembly(GO:0051964) |
| 0.0 | 0.4 | GO:0016973 | poly(A)+ mRNA export from nucleus(GO:0016973) |
| 0.0 | 1.8 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
| 0.0 | 0.0 | GO:0050859 | negative regulation of B cell receptor signaling pathway(GO:0050859) |
| 0.0 | 0.5 | GO:0035115 | embryonic forelimb morphogenesis(GO:0035115) |
| 0.0 | 0.2 | GO:0070072 | proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
| 0.0 | 0.2 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
| 0.0 | 0.1 | GO:0051673 | membrane disruption in other organism(GO:0051673) |
| 0.0 | 0.4 | GO:0006622 | protein targeting to lysosome(GO:0006622) |
| 0.0 | 0.2 | GO:1904715 | negative regulation of chaperone-mediated autophagy(GO:1904715) |
| 0.0 | 0.2 | GO:0030157 | pancreatic juice secretion(GO:0030157) |
| 0.0 | 0.5 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
| 0.0 | 3.1 | GO:0006367 | transcription initiation from RNA polymerase II promoter(GO:0006367) |
| 0.0 | 1.4 | GO:0019233 | sensory perception of pain(GO:0019233) |
| 0.0 | 0.1 | GO:0043031 | negative regulation of macrophage activation(GO:0043031) |
| 0.0 | 0.0 | GO:0014878 | response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878) |
| 0.0 | 0.1 | GO:0006659 | phosphatidylserine biosynthetic process(GO:0006659) |
| 0.0 | 0.1 | GO:0006982 | response to lipid hydroperoxide(GO:0006982) |
| 0.0 | 0.0 | GO:0045643 | regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) |
| 0.0 | 0.1 | GO:0018231 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
| 0.0 | 0.1 | GO:0080182 | histone H3-K4 trimethylation(GO:0080182) |
| 0.0 | 0.5 | GO:0019228 | neuronal action potential(GO:0019228) |
| 0.0 | 0.1 | GO:0044861 | protein localization to plasma membrane raft(GO:0044860) protein transport into plasma membrane raft(GO:0044861) |
| 0.0 | 0.7 | GO:0006352 | DNA-templated transcription, initiation(GO:0006352) |
| 0.0 | 2.0 | GO:0008277 | regulation of G-protein coupled receptor protein signaling pathway(GO:0008277) |
| 0.0 | 0.5 | GO:0042461 | photoreceptor cell development(GO:0042461) |
| 0.0 | 0.1 | GO:0006121 | mitochondrial electron transport, succinate to ubiquinone(GO:0006121) |
| 0.0 | 0.8 | GO:0015909 | long-chain fatty acid transport(GO:0015909) |
| 0.0 | 0.9 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
| 0.0 | 0.3 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
| 0.0 | 0.1 | GO:0010818 | T cell chemotaxis(GO:0010818) |
| 0.0 | 0.4 | GO:0045907 | positive regulation of vasoconstriction(GO:0045907) |
| 0.0 | 0.8 | GO:0021762 | substantia nigra development(GO:0021762) |
| 0.0 | 3.4 | GO:0016579 | protein deubiquitination(GO:0016579) |
| 0.0 | 0.9 | GO:0000245 | spliceosomal complex assembly(GO:0000245) |
| 0.0 | 0.1 | GO:0070307 | lens fiber cell development(GO:0070307) |
| 0.0 | 0.2 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
| 0.0 | 0.1 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 0.0 | 0.1 | GO:0070120 | ciliary neurotrophic factor-mediated signaling pathway(GO:0070120) |
| 0.0 | 0.2 | GO:0043162 | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162) |
| 0.0 | 0.0 | GO:0033693 | neurofilament bundle assembly(GO:0033693) |
| 0.0 | 0.1 | GO:0038044 | transforming growth factor-beta secretion(GO:0038044) |
| 0.0 | 0.1 | GO:0010719 | negative regulation of epithelial to mesenchymal transition(GO:0010719) |
| 0.0 | 0.3 | GO:0006198 | cAMP catabolic process(GO:0006198) |
| 0.0 | 0.1 | GO:0006189 | 'de novo' IMP biosynthetic process(GO:0006189) |
| 0.0 | 0.2 | GO:0060575 | intestinal epithelial cell differentiation(GO:0060575) |
| 0.0 | 1.1 | GO:0007224 | smoothened signaling pathway(GO:0007224) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.4 | 13.1 | GO:0031084 | BLOC-2 complex(GO:0031084) |
| 3.0 | 12.1 | GO:1990796 | photoreceptor cell terminal bouton(GO:1990796) |
| 1.9 | 11.3 | GO:1990131 | Gtr1-Gtr2 GTPase complex(GO:1990131) |
| 1.1 | 6.4 | GO:0033263 | CORVET complex(GO:0033263) |
| 1.1 | 6.4 | GO:0000221 | vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221) |
| 1.0 | 9.2 | GO:0030896 | checkpoint clamp complex(GO:0030896) |
| 1.0 | 4.8 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 0.9 | 6.5 | GO:1903439 | calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440) |
| 0.9 | 9.0 | GO:0016589 | NURF complex(GO:0016589) |
| 0.9 | 6.8 | GO:0098560 | cytoplasmic side of late endosome membrane(GO:0098560) |
| 0.8 | 10.7 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 0.8 | 4.1 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.8 | 8.4 | GO:0000439 | core TFIIH complex(GO:0000439) |
| 0.8 | 6.1 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
| 0.7 | 3.0 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
| 0.6 | 3.7 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
| 0.6 | 2.3 | GO:0071149 | TEAD-2-YAP complex(GO:0071149) |
| 0.6 | 2.3 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
| 0.6 | 4.6 | GO:0044294 | dendritic growth cone(GO:0044294) |
| 0.6 | 4.0 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
| 0.6 | 6.2 | GO:0045252 | oxoglutarate dehydrogenase complex(GO:0045252) |
| 0.6 | 2.8 | GO:0034991 | nuclear meiotic cohesin complex(GO:0034991) |
| 0.5 | 2.2 | GO:0055087 | Ski complex(GO:0055087) |
| 0.5 | 3.8 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
| 0.5 | 3.0 | GO:0031313 | extrinsic component of endosome membrane(GO:0031313) |
| 0.5 | 2.5 | GO:1990246 | uniplex complex(GO:1990246) |
| 0.5 | 1.9 | GO:0005896 | interleukin-6 receptor complex(GO:0005896) |
| 0.4 | 4.0 | GO:0005955 | calcineurin complex(GO:0005955) |
| 0.4 | 0.4 | GO:0019034 | viral replication complex(GO:0019034) |
| 0.4 | 3.9 | GO:0097470 | ribbon synapse(GO:0097470) |
| 0.4 | 1.7 | GO:0005967 | mitochondrial pyruvate dehydrogenase complex(GO:0005967) |
| 0.4 | 8.6 | GO:0043220 | Schmidt-Lanterman incisure(GO:0043220) |
| 0.4 | 1.6 | GO:0048476 | Holliday junction resolvase complex(GO:0048476) |
| 0.4 | 0.8 | GO:0033186 | CAF-1 complex(GO:0033186) |
| 0.4 | 2.3 | GO:0030678 | mitochondrial ribonuclease P complex(GO:0030678) |
| 0.3 | 12.4 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
| 0.3 | 1.0 | GO:0097058 | CRLF-CLCF1 complex(GO:0097058) |
| 0.3 | 7.1 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.3 | 1.3 | GO:0097135 | cyclin E2-CDK2 complex(GO:0097135) |
| 0.3 | 1.3 | GO:0032144 | 4-aminobutyrate transaminase complex(GO:0032144) |
| 0.3 | 2.2 | GO:0070695 | FHF complex(GO:0070695) |
| 0.3 | 7.5 | GO:0010369 | chromocenter(GO:0010369) |
| 0.3 | 0.3 | GO:1990769 | proximal neuron projection(GO:1990769) |
| 0.3 | 1.1 | GO:0034751 | aryl hydrocarbon receptor complex(GO:0034751) |
| 0.3 | 2.3 | GO:0042824 | MHC class I peptide loading complex(GO:0042824) |
| 0.2 | 2.2 | GO:0071986 | Ragulator complex(GO:0071986) |
| 0.2 | 2.4 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
| 0.2 | 5.3 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.2 | 0.7 | GO:0035189 | Rb-E2F complex(GO:0035189) |
| 0.2 | 1.1 | GO:0035838 | growing cell tip(GO:0035838) |
| 0.2 | 1.5 | GO:0098575 | lumenal side of lysosomal membrane(GO:0098575) |
| 0.2 | 5.5 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.2 | 0.6 | GO:0009330 | DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330) |
| 0.2 | 0.6 | GO:0098559 | cytoplasmic side of early endosome membrane(GO:0098559) |
| 0.2 | 14.4 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.2 | 2.7 | GO:0000153 | cytoplasmic ubiquitin ligase complex(GO:0000153) |
| 0.2 | 3.0 | GO:0030008 | TRAPP complex(GO:0030008) |
| 0.2 | 1.7 | GO:0035253 | ciliary rootlet(GO:0035253) |
| 0.2 | 0.7 | GO:0070044 | synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044) |
| 0.2 | 2.3 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.2 | 11.2 | GO:0016235 | aggresome(GO:0016235) |
| 0.2 | 1.8 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.2 | 1.7 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 0.1 | 0.3 | GO:0020016 | ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018) |
| 0.1 | 1.7 | GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex(GO:0031464) |
| 0.1 | 0.4 | GO:1990876 | cytoplasmic side of nuclear pore(GO:1990876) |
| 0.1 | 1.5 | GO:0070775 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
| 0.1 | 0.9 | GO:0001740 | Barr body(GO:0001740) |
| 0.1 | 10.1 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.1 | 1.0 | GO:0070765 | gamma-secretase complex(GO:0070765) |
| 0.1 | 0.8 | GO:0000172 | ribonuclease MRP complex(GO:0000172) |
| 0.1 | 1.8 | GO:0099634 | postsynaptic specialization membrane(GO:0099634) |
| 0.1 | 2.1 | GO:0042405 | nuclear inclusion body(GO:0042405) |
| 0.1 | 0.3 | GO:0034657 | GID complex(GO:0034657) |
| 0.1 | 0.4 | GO:0098592 | cytoplasmic side of apical plasma membrane(GO:0098592) |
| 0.1 | 2.2 | GO:0033276 | transcription factor TFTC complex(GO:0033276) |
| 0.1 | 1.4 | GO:0043190 | ATP-binding cassette (ABC) transporter complex(GO:0043190) |
| 0.1 | 1.4 | GO:0032039 | integrator complex(GO:0032039) |
| 0.1 | 45.8 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.1 | 1.5 | GO:0005915 | zonula adherens(GO:0005915) |
| 0.1 | 0.8 | GO:0032389 | MutLalpha complex(GO:0032389) |
| 0.1 | 2.4 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.1 | 1.1 | GO:0045179 | apical cortex(GO:0045179) |
| 0.1 | 0.5 | GO:0097452 | GAIT complex(GO:0097452) |
| 0.1 | 1.8 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.1 | 0.3 | GO:0005960 | glycine cleavage complex(GO:0005960) |
| 0.1 | 1.3 | GO:0035631 | CD40 receptor complex(GO:0035631) |
| 0.1 | 12.1 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.1 | 13.8 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 0.1 | 1.6 | GO:0071682 | endocytic vesicle lumen(GO:0071682) |
| 0.1 | 0.6 | GO:1990635 | proximal dendrite(GO:1990635) |
| 0.1 | 0.8 | GO:0000801 | central element(GO:0000801) |
| 0.1 | 1.8 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 0.1 | 2.5 | GO:0097381 | photoreceptor disc membrane(GO:0097381) |
| 0.1 | 0.6 | GO:0071012 | catalytic step 1 spliceosome(GO:0071012) |
| 0.1 | 0.9 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.1 | 0.3 | GO:0031510 | SUMO activating enzyme complex(GO:0031510) |
| 0.1 | 1.0 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.1 | 8.2 | GO:0070821 | tertiary granule membrane(GO:0070821) |
| 0.1 | 4.5 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.1 | 0.3 | GO:0097362 | MCM8-MCM9 complex(GO:0097362) |
| 0.1 | 2.1 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
| 0.1 | 1.2 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.1 | 0.7 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
| 0.1 | 0.6 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
| 0.1 | 0.8 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 0.1 | 2.4 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
| 0.1 | 0.3 | GO:1903349 | extrinsic component of omegasome membrane(GO:0097629) omegasome membrane(GO:1903349) |
| 0.1 | 7.2 | GO:0005746 | mitochondrial respiratory chain(GO:0005746) |
| 0.1 | 0.4 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
| 0.1 | 12.9 | GO:0030018 | Z disc(GO:0030018) |
| 0.1 | 0.7 | GO:0097487 | platelet dense granule membrane(GO:0031088) multivesicular body, internal vesicle(GO:0097487) |
| 0.1 | 1.1 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.1 | 0.5 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
| 0.1 | 1.7 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
| 0.1 | 0.1 | GO:0008024 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) |
| 0.1 | 7.2 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.1 | 0.5 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 0.1 | 7.6 | GO:0005814 | centriole(GO:0005814) |
| 0.1 | 8.5 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.1 | 0.4 | GO:0030915 | Smc5-Smc6 complex(GO:0030915) |
| 0.1 | 0.5 | GO:0016461 | unconventional myosin complex(GO:0016461) |
| 0.0 | 3.8 | GO:0042641 | actomyosin(GO:0042641) |
| 0.0 | 1.6 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.0 | 1.2 | GO:0031674 | I band(GO:0031674) |
| 0.0 | 1.3 | GO:0005669 | transcription factor TFIID complex(GO:0005669) |
| 0.0 | 0.6 | GO:0034366 | spherical high-density lipoprotein particle(GO:0034366) chromaffin granule(GO:0042583) |
| 0.0 | 0.1 | GO:0038039 | G-protein coupled receptor heterodimeric complex(GO:0038039) |
| 0.0 | 0.4 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
| 0.0 | 0.1 | GO:0034685 | integrin alphav-beta6 complex(GO:0034685) |
| 0.0 | 0.4 | GO:0005638 | lamin filament(GO:0005638) |
| 0.0 | 0.2 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.0 | 0.8 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.0 | 1.0 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
| 0.0 | 0.6 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.0 | 1.6 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
| 0.0 | 0.2 | GO:0016342 | catenin complex(GO:0016342) |
| 0.0 | 5.0 | GO:0005884 | actin filament(GO:0005884) |
| 0.0 | 1.4 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.0 | 0.3 | GO:0061617 | MICOS complex(GO:0061617) |
| 0.0 | 0.2 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 0.0 | 1.3 | GO:0090544 | BAF-type complex(GO:0090544) |
| 0.0 | 1.3 | GO:0045178 | basal part of cell(GO:0045178) |
| 0.0 | 0.1 | GO:0071256 | Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256) |
| 0.0 | 0.1 | GO:0000333 | telomerase catalytic core complex(GO:0000333) |
| 0.0 | 1.2 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.0 | 0.1 | GO:0070110 | ciliary neurotrophic factor receptor complex(GO:0070110) |
| 0.0 | 1.1 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 0.3 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.0 | 4.2 | GO:0000776 | kinetochore(GO:0000776) |
| 0.0 | 1.5 | GO:0000786 | nucleosome(GO:0000786) |
| 0.0 | 0.4 | GO:0000346 | transcription export complex(GO:0000346) |
| 0.0 | 0.2 | GO:0034388 | Pwp2p-containing subcomplex of 90S preribosome(GO:0034388) |
| 0.0 | 0.4 | GO:0036038 | MKS complex(GO:0036038) |
| 0.0 | 2.6 | GO:0005604 | basement membrane(GO:0005604) |
| 0.0 | 0.1 | GO:0034457 | Mpp10 complex(GO:0034457) |
| 0.0 | 0.3 | GO:0097255 | R2TP complex(GO:0097255) |
| 0.0 | 1.3 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.0 | 0.6 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.0 | 11.4 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.0 | 0.4 | GO:0071437 | invadopodium(GO:0071437) |
| 0.0 | 1.7 | GO:0005902 | microvillus(GO:0005902) |
| 0.0 | 0.4 | GO:0000815 | ESCRT III complex(GO:0000815) |
| 0.0 | 0.8 | GO:1990391 | DNA repair complex(GO:1990391) |
| 0.0 | 2.9 | GO:1904813 | ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813) |
| 0.0 | 1.4 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.0 | 1.5 | GO:0000118 | histone deacetylase complex(GO:0000118) |
| 0.0 | 0.3 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
| 0.0 | 0.1 | GO:0005854 | nascent polypeptide-associated complex(GO:0005854) |
| 0.0 | 0.3 | GO:0034362 | low-density lipoprotein particle(GO:0034362) |
| 0.0 | 0.4 | GO:0030057 | desmosome(GO:0030057) |
| 0.0 | 1.6 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.0 | 0.1 | GO:0070469 | respiratory chain(GO:0070469) |
| 0.0 | 0.0 | GO:0071203 | WASH complex(GO:0071203) |
| 0.0 | 0.3 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.0 | 1.7 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.0 | 0.1 | GO:0034274 | Atg12-Atg5-Atg16 complex(GO:0034274) |
| 0.0 | 0.3 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.0 | 0.6 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.0 | 0.4 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.0 | 0.0 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.4 | 10.1 | GO:0015130 | mevalonate transmembrane transporter activity(GO:0015130) |
| 2.3 | 11.5 | GO:0004489 | methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489) |
| 2.3 | 13.8 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
| 2.0 | 5.9 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
| 1.9 | 9.4 | GO:0070905 | serine binding(GO:0070905) |
| 1.8 | 5.4 | GO:0032767 | copper-dependent protein binding(GO:0032767) |
| 1.5 | 4.6 | GO:0008746 | NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652) |
| 1.5 | 9.2 | GO:0008853 | exodeoxyribonuclease III activity(GO:0008853) |
| 1.5 | 5.9 | GO:0034602 | oxoglutarate dehydrogenase (NAD+) activity(GO:0034602) |
| 1.2 | 5.9 | GO:1990460 | leptin receptor binding(GO:1990460) |
| 1.2 | 12.8 | GO:0030274 | LIM domain binding(GO:0030274) |
| 1.1 | 12.1 | GO:0050544 | arachidonic acid binding(GO:0050544) |
| 1.1 | 11.7 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 1.0 | 13.5 | GO:0039706 | co-receptor binding(GO:0039706) BMP receptor binding(GO:0070700) |
| 1.0 | 4.1 | GO:0043398 | HLH domain binding(GO:0043398) |
| 0.9 | 2.8 | GO:0004853 | uroporphyrinogen decarboxylase activity(GO:0004853) |
| 0.9 | 6.5 | GO:0097643 | amylin receptor activity(GO:0097643) |
| 0.9 | 10.7 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 0.9 | 5.1 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
| 0.9 | 2.6 | GO:0019912 | cyclin-dependent protein kinase activating kinase activity(GO:0019912) |
| 0.8 | 2.5 | GO:0003943 | N-acetylgalactosamine-4-sulfatase activity(GO:0003943) |
| 0.8 | 2.3 | GO:0008534 | oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534) |
| 0.8 | 4.6 | GO:0005119 | smoothened binding(GO:0005119) |
| 0.8 | 3.0 | GO:0034057 | RNA strand-exchange activity(GO:0034057) |
| 0.7 | 2.2 | GO:0071558 | histone demethylase activity (H3-K27 specific)(GO:0071558) |
| 0.7 | 11.4 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 0.7 | 2.8 | GO:0036033 | mediator complex binding(GO:0036033) |
| 0.7 | 2.7 | GO:0033829 | O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829) |
| 0.7 | 5.9 | GO:0008559 | xenobiotic-transporting ATPase activity(GO:0008559) |
| 0.7 | 3.3 | GO:1990189 | peptide-serine-N-acetyltransferase activity(GO:1990189) |
| 0.6 | 1.9 | GO:0019981 | interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981) |
| 0.6 | 3.1 | GO:0004699 | calcium-independent protein kinase C activity(GO:0004699) |
| 0.6 | 4.2 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) |
| 0.6 | 5.2 | GO:0030976 | thiamine pyrophosphate binding(GO:0030976) |
| 0.6 | 2.3 | GO:0042132 | fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132) |
| 0.6 | 4.0 | GO:0016618 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
| 0.5 | 4.9 | GO:0001225 | RNA polymerase II transcription coactivator binding(GO:0001225) |
| 0.5 | 4.8 | GO:0001875 | lipopolysaccharide receptor activity(GO:0001875) |
| 0.5 | 6.4 | GO:0031386 | protein tag(GO:0031386) |
| 0.5 | 1.6 | GO:0004416 | hydroxyacylglutathione hydrolase activity(GO:0004416) |
| 0.5 | 3.6 | GO:0015183 | L-aspartate transmembrane transporter activity(GO:0015183) |
| 0.5 | 2.0 | GO:0005105 | type 1 fibroblast growth factor receptor binding(GO:0005105) |
| 0.5 | 6.1 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 0.5 | 5.1 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
| 0.5 | 1.4 | GO:0015218 | pyrimidine nucleotide transmembrane transporter activity(GO:0015218) |
| 0.5 | 1.8 | GO:0015319 | sodium:inorganic phosphate symporter activity(GO:0015319) |
| 0.4 | 4.8 | GO:0016494 | C-X-C chemokine receptor activity(GO:0016494) |
| 0.4 | 1.3 | GO:0015439 | heme-transporting ATPase activity(GO:0015439) |
| 0.4 | 8.5 | GO:0005402 | sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) |
| 0.4 | 1.7 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
| 0.4 | 3.3 | GO:0034597 | phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) |
| 0.4 | 2.1 | GO:0050436 | microfibril binding(GO:0050436) |
| 0.4 | 12.0 | GO:0000062 | fatty-acyl-CoA binding(GO:0000062) |
| 0.4 | 23.7 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.4 | 2.0 | GO:0019144 | ADP-sugar diphosphatase activity(GO:0019144) |
| 0.4 | 1.2 | GO:0004819 | glutamine-tRNA ligase activity(GO:0004819) |
| 0.4 | 4.0 | GO:0033192 | calmodulin-dependent protein phosphatase activity(GO:0033192) |
| 0.4 | 7.7 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
| 0.4 | 1.5 | GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616) |
| 0.4 | 2.6 | GO:0003997 | acyl-CoA oxidase activity(GO:0003997) |
| 0.4 | 1.5 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
| 0.4 | 1.1 | GO:0070579 | methylcytosine dioxygenase activity(GO:0070579) |
| 0.4 | 0.4 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
| 0.4 | 3.2 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
| 0.4 | 6.3 | GO:0003857 | 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857) |
| 0.3 | 2.1 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
| 0.3 | 6.9 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.3 | 2.1 | GO:0032564 | adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564) |
| 0.3 | 2.1 | GO:0019776 | Atg8 ligase activity(GO:0019776) |
| 0.3 | 3.1 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 0.3 | 1.3 | GO:0008384 | IkappaB kinase activity(GO:0008384) |
| 0.3 | 5.9 | GO:0005346 | adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) |
| 0.3 | 13.0 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.3 | 1.3 | GO:0003867 | 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298) |
| 0.3 | 0.9 | GO:0004574 | oligo-1,6-glucosidase activity(GO:0004574) |
| 0.3 | 10.3 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.3 | 1.5 | GO:0044729 | hemi-methylated DNA-binding(GO:0044729) |
| 0.3 | 1.7 | GO:0008240 | tripeptidyl-peptidase activity(GO:0008240) |
| 0.3 | 2.0 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
| 0.3 | 2.6 | GO:0009922 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.3 | 6.2 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.3 | 1.1 | GO:0035651 | AP-3 adaptor complex binding(GO:0035651) |
| 0.3 | 0.8 | GO:0004677 | DNA-dependent protein kinase activity(GO:0004677) |
| 0.3 | 0.8 | GO:0008309 | double-stranded DNA exodeoxyribonuclease activity(GO:0008309) |
| 0.3 | 0.8 | GO:0005483 | soluble NSF attachment protein activity(GO:0005483) |
| 0.3 | 1.1 | GO:0043426 | MRF binding(GO:0043426) |
| 0.3 | 12.7 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.2 | 3.2 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
| 0.2 | 0.7 | GO:0071535 | RING-like zinc finger domain binding(GO:0071535) |
| 0.2 | 0.2 | GO:0070538 | oleic acid binding(GO:0070538) |
| 0.2 | 1.2 | GO:0071074 | eukaryotic initiation factor eIF2 binding(GO:0071074) |
| 0.2 | 0.9 | GO:0016936 | galactoside binding(GO:0016936) |
| 0.2 | 1.7 | GO:0019763 | immunoglobulin receptor activity(GO:0019763) |
| 0.2 | 1.7 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 0.2 | 0.6 | GO:0000253 | 3-keto sterol reductase activity(GO:0000253) |
| 0.2 | 1.0 | GO:0005127 | ciliary neurotrophic factor receptor binding(GO:0005127) |
| 0.2 | 3.1 | GO:0004526 | ribonuclease P activity(GO:0004526) |
| 0.2 | 0.4 | GO:0001129 | RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132) |
| 0.2 | 1.4 | GO:0061665 | SUMO ligase activity(GO:0061665) |
| 0.2 | 1.1 | GO:0003998 | acylphosphatase activity(GO:0003998) |
| 0.2 | 3.6 | GO:0016671 | oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671) |
| 0.2 | 20.8 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
| 0.2 | 2.5 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 0.2 | 1.9 | GO:0003996 | acyl-CoA ligase activity(GO:0003996) |
| 0.2 | 2.1 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
| 0.2 | 0.7 | GO:0047391 | alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391) |
| 0.2 | 0.5 | GO:0001147 | transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160) |
| 0.2 | 14.1 | GO:0005507 | copper ion binding(GO:0005507) |
| 0.2 | 1.9 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
| 0.2 | 0.5 | GO:0001003 | polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003) |
| 0.2 | 1.6 | GO:0008821 | crossover junction endodeoxyribonuclease activity(GO:0008821) |
| 0.2 | 0.5 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
| 0.2 | 0.3 | GO:0044388 | small protein activating enzyme binding(GO:0044388) |
| 0.2 | 2.0 | GO:0031852 | mu-type opioid receptor binding(GO:0031852) |
| 0.1 | 1.5 | GO:0000340 | RNA 7-methylguanosine cap binding(GO:0000340) |
| 0.1 | 1.3 | GO:0016641 | oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641) |
| 0.1 | 1.9 | GO:0001083 | transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) |
| 0.1 | 1.0 | GO:0048039 | ubiquinone binding(GO:0048039) |
| 0.1 | 1.8 | GO:0016742 | hydroxymethyl-, formyl- and related transferase activity(GO:0016742) |
| 0.1 | 0.4 | GO:0033867 | Fas-activated serine/threonine kinase activity(GO:0033867) |
| 0.1 | 3.6 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.1 | 0.7 | GO:0061676 | importin-alpha family protein binding(GO:0061676) |
| 0.1 | 3.9 | GO:0016881 | acid-amino acid ligase activity(GO:0016881) |
| 0.1 | 4.1 | GO:0036442 | hydrogen-exporting ATPase activity(GO:0036442) |
| 0.1 | 0.8 | GO:0035500 | MH2 domain binding(GO:0035500) |
| 0.1 | 0.1 | GO:0036435 | K48-linked polyubiquitin binding(GO:0036435) |
| 0.1 | 0.8 | GO:0032138 | single base insertion or deletion binding(GO:0032138) |
| 0.1 | 1.5 | GO:0035256 | G-protein coupled glutamate receptor binding(GO:0035256) |
| 0.1 | 0.2 | GO:0071987 | WD40-repeat domain binding(GO:0071987) |
| 0.1 | 0.3 | GO:0004087 | carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088) |
| 0.1 | 12.3 | GO:0050660 | flavin adenine dinucleotide binding(GO:0050660) |
| 0.1 | 2.9 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.1 | 0.3 | GO:0033149 | FFAT motif binding(GO:0033149) |
| 0.1 | 0.9 | GO:0032051 | clathrin light chain binding(GO:0032051) |
| 0.1 | 0.8 | GO:0035614 | snRNA stem-loop binding(GO:0035614) |
| 0.1 | 1.3 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.1 | 2.4 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
| 0.1 | 5.4 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.1 | 2.6 | GO:0043495 | protein anchor(GO:0043495) |
| 0.1 | 1.3 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.1 | 1.4 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.1 | 4.3 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.1 | 2.7 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
| 0.1 | 1.3 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.1 | 0.7 | GO:0008174 | mRNA methyltransferase activity(GO:0008174) |
| 0.1 | 1.5 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.1 | 0.3 | GO:0004828 | serine-tRNA ligase activity(GO:0004828) |
| 0.1 | 0.5 | GO:0031728 | CCR3 chemokine receptor binding(GO:0031728) |
| 0.1 | 1.4 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
| 0.1 | 1.3 | GO:0019789 | SUMO transferase activity(GO:0019789) |
| 0.1 | 0.9 | GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162) |
| 0.1 | 8.7 | GO:0008094 | DNA-dependent ATPase activity(GO:0008094) |
| 0.1 | 14.9 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 0.1 | 6.5 | GO:0002039 | p53 binding(GO:0002039) |
| 0.1 | 2.2 | GO:0071837 | HMG box domain binding(GO:0071837) |
| 0.1 | 0.7 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.1 | 0.4 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
| 0.1 | 2.5 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.1 | 0.5 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
| 0.1 | 37.2 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
| 0.1 | 3.1 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.1 | 0.2 | GO:0043891 | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891) |
| 0.1 | 2.4 | GO:0047555 | 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555) |
| 0.1 | 1.4 | GO:0043274 | phospholipase binding(GO:0043274) |
| 0.1 | 0.1 | GO:0000104 | succinate dehydrogenase activity(GO:0000104) |
| 0.1 | 0.3 | GO:0003976 | UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976) |
| 0.1 | 0.1 | GO:0030984 | kininogen binding(GO:0030984) |
| 0.1 | 0.4 | GO:0001016 | RNA polymerase III regulatory region DNA binding(GO:0001016) |
| 0.1 | 0.5 | GO:0016717 | oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717) |
| 0.1 | 4.6 | GO:0051287 | NAD binding(GO:0051287) |
| 0.1 | 2.4 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.1 | 2.8 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
| 0.1 | 5.2 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.1 | 3.3 | GO:0004520 | endodeoxyribonuclease activity(GO:0004520) |
| 0.1 | 0.3 | GO:0004047 | aminomethyltransferase activity(GO:0004047) |
| 0.1 | 0.5 | GO:0004565 | beta-galactosidase activity(GO:0004565) |
| 0.1 | 3.1 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.1 | 0.9 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.1 | 0.5 | GO:0016997 | exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) |
| 0.1 | 0.3 | GO:0004802 | transketolase activity(GO:0004802) |
| 0.1 | 2.6 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.1 | 0.7 | GO:0001042 | RNA polymerase I core binding(GO:0001042) |
| 0.1 | 1.7 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
| 0.1 | 0.2 | GO:0035515 | oxidative RNA demethylase activity(GO:0035515) |
| 0.1 | 1.3 | GO:0004707 | MAP kinase activity(GO:0004707) |
| 0.1 | 6.5 | GO:0019903 | protein phosphatase binding(GO:0019903) |
| 0.1 | 1.1 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.1 | 1.3 | GO:0019992 | diacylglycerol binding(GO:0019992) |
| 0.1 | 1.8 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.1 | 1.8 | GO:0008171 | O-methyltransferase activity(GO:0008171) |
| 0.1 | 0.2 | GO:0070180 | large ribosomal subunit rRNA binding(GO:0070180) |
| 0.1 | 1.3 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
| 0.1 | 2.1 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.1 | 0.2 | GO:0047275 | glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275) |
| 0.1 | 2.1 | GO:0008378 | galactosyltransferase activity(GO:0008378) |
| 0.1 | 0.3 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
| 0.1 | 0.4 | GO:0043008 | ATP-dependent protein binding(GO:0043008) |
| 0.1 | 0.3 | GO:0047184 | 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) |
| 0.1 | 1.8 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 0.1 | 0.7 | GO:0004985 | opioid receptor activity(GO:0004985) |
| 0.1 | 0.3 | GO:0004331 | 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331) |
| 0.1 | 0.6 | GO:0097100 | supercoiled DNA binding(GO:0097100) |
| 0.1 | 3.2 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.1 | 0.5 | GO:0004305 | ethanolamine kinase activity(GO:0004305) |
| 0.0 | 0.5 | GO:0008097 | 5S rRNA binding(GO:0008097) |
| 0.0 | 0.6 | GO:0015143 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
| 0.0 | 0.7 | GO:1990381 | ubiquitin-specific protease binding(GO:1990381) |
| 0.0 | 0.9 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.0 | 0.4 | GO:0070097 | delta-catenin binding(GO:0070097) |
| 0.0 | 5.1 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
| 0.0 | 0.3 | GO:0004045 | aminoacyl-tRNA hydrolase activity(GO:0004045) |
| 0.0 | 0.3 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 0.0 | 0.8 | GO:0005537 | mannose binding(GO:0005537) |
| 0.0 | 0.6 | GO:0051787 | misfolded protein binding(GO:0051787) |
| 0.0 | 1.0 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
| 0.0 | 0.6 | GO:0043225 | anion transmembrane-transporting ATPase activity(GO:0043225) |
| 0.0 | 0.8 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 0.0 | 0.2 | GO:0008466 | glycogenin glucosyltransferase activity(GO:0008466) |
| 0.0 | 0.9 | GO:0016646 | oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646) |
| 0.0 | 1.0 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.0 | 24.0 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
| 0.0 | 0.5 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.0 | 2.4 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 0.0 | 0.2 | GO:0086077 | gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077) |
| 0.0 | 0.1 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
| 0.0 | 2.2 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.0 | 0.2 | GO:0034452 | dynactin binding(GO:0034452) |
| 0.0 | 0.9 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.0 | 1.8 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.0 | 0.8 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.0 | 0.6 | GO:0031491 | nucleosome binding(GO:0031491) |
| 0.0 | 0.1 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
| 0.0 | 0.9 | GO:0005504 | fatty acid binding(GO:0005504) |
| 0.0 | 0.2 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
| 0.0 | 0.1 | GO:0004897 | ciliary neurotrophic factor receptor activity(GO:0004897) |
| 0.0 | 4.1 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 0.5 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.0 | 0.5 | GO:0005337 | nucleoside transmembrane transporter activity(GO:0005337) |
| 0.0 | 1.9 | GO:0019213 | deacetylase activity(GO:0019213) |
| 0.0 | 0.4 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
| 0.0 | 0.1 | GO:0050309 | glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309) |
| 0.0 | 0.1 | GO:0030158 | protein xylosyltransferase activity(GO:0030158) |
| 0.0 | 0.1 | GO:0004618 | phosphoglycerate kinase activity(GO:0004618) |
| 0.0 | 0.3 | GO:0047498 | calcium-dependent phospholipase A2 activity(GO:0047498) |
| 0.0 | 0.2 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 0.0 | 1.6 | GO:0004177 | aminopeptidase activity(GO:0004177) |
| 0.0 | 0.2 | GO:0001223 | transcription coactivator binding(GO:0001223) |
| 0.0 | 0.3 | GO:0005161 | platelet-derived growth factor receptor binding(GO:0005161) |
| 0.0 | 0.3 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.0 | 1.0 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.0 | 0.5 | GO:0005248 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
| 0.0 | 0.3 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.0 | 1.1 | GO:0003707 | steroid hormone receptor activity(GO:0003707) |
| 0.0 | 0.3 | GO:0005542 | folic acid binding(GO:0005542) |
| 0.0 | 0.7 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.0 | 0.5 | GO:0001848 | complement binding(GO:0001848) |
| 0.0 | 0.0 | GO:0005137 | interleukin-5 receptor binding(GO:0005137) |
| 0.0 | 0.4 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.0 | 3.9 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.0 | 0.1 | GO:0060422 | peptidyl-dipeptidase inhibitor activity(GO:0060422) |
| 0.0 | 0.2 | GO:0005522 | profilin binding(GO:0005522) |
| 0.0 | 0.2 | GO:0008430 | selenium binding(GO:0008430) |
| 0.0 | 0.3 | GO:0017081 | chloride channel regulator activity(GO:0017081) |
| 0.0 | 0.3 | GO:0016780 | phosphotransferase activity, for other substituted phosphate groups(GO:0016780) |
| 0.0 | 0.1 | GO:0045295 | gamma-catenin binding(GO:0045295) |
| 0.0 | 0.4 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.0 | 0.0 | GO:0004663 | Rab geranylgeranyltransferase activity(GO:0004663) |
| 0.0 | 0.1 | GO:0000400 | DNA secondary structure binding(GO:0000217) four-way junction DNA binding(GO:0000400) |
| 0.0 | 0.2 | GO:0015250 | water channel activity(GO:0015250) |
| 0.0 | 0.7 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.0 | 4.1 | GO:0015631 | tubulin binding(GO:0015631) |
| 0.0 | 0.1 | GO:0034190 | apolipoprotein receptor binding(GO:0034190) high-density lipoprotein particle receptor binding(GO:0070653) |
| 0.0 | 0.2 | GO:0008020 | G-protein coupled photoreceptor activity(GO:0008020) |
| 0.0 | 0.6 | GO:0008009 | chemokine activity(GO:0008009) |
| 0.0 | 0.0 | GO:0016774 | phosphotransferase activity, carboxyl group as acceptor(GO:0016774) |
| 0.0 | 0.0 | GO:0016812 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812) |
| 0.0 | 1.8 | GO:0005178 | integrin binding(GO:0005178) |
| 0.0 | 0.8 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.0 | 0.1 | GO:0004065 | arylsulfatase activity(GO:0004065) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 2.5 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.3 | 3.8 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 0.3 | 1.9 | ST STAT3 PATHWAY | STAT3 Pathway |
| 0.2 | 8.0 | PID WNT CANONICAL PATHWAY | Canonical Wnt signaling pathway |
| 0.2 | 1.6 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.2 | 12.4 | PID BMP PATHWAY | BMP receptor signaling |
| 0.2 | 11.9 | PID CD8 TCR DOWNSTREAM PATHWAY | Downstream signaling in naïve CD8+ T cells |
| 0.2 | 6.1 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.2 | 8.7 | PID ATM PATHWAY | ATM pathway |
| 0.2 | 9.4 | ST P38 MAPK PATHWAY | p38 MAPK Pathway |
| 0.2 | 13.2 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
| 0.1 | 5.6 | PID S1P S1P3 PATHWAY | S1P3 pathway |
| 0.1 | 2.1 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 0.1 | 1.2 | PID VEGFR1 PATHWAY | VEGFR1 specific signals |
| 0.1 | 10.6 | PID IL2 1PATHWAY | IL2-mediated signaling events |
| 0.1 | 5.6 | PID THROMBIN PAR1 PATHWAY | PAR1-mediated thrombin signaling events |
| 0.1 | 4.6 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.1 | 2.3 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.1 | 2.0 | PID AR NONGENOMIC PATHWAY | Nongenotropic Androgen signaling |
| 0.1 | 9.9 | PID MTOR 4PATHWAY | mTOR signaling pathway |
| 0.1 | 9.4 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.1 | 1.4 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.1 | 8.1 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.1 | 1.6 | ST G ALPHA S PATHWAY | G alpha s Pathway |
| 0.1 | 4.1 | PID TXA2PATHWAY | Thromboxane A2 receptor signaling |
| 0.1 | 4.6 | PID ARF6 PATHWAY | Arf6 signaling events |
| 0.1 | 5.9 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.1 | 2.3 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.1 | 2.6 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.1 | 0.9 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.1 | 6.9 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.1 | 2.5 | PID P73PATHWAY | p73 transcription factor network |
| 0.1 | 3.6 | PID FOXO PATHWAY | FoxO family signaling |
| 0.1 | 2.5 | PID RHODOPSIN PATHWAY | Visual signal transduction: Rods |
| 0.1 | 1.8 | PID MAPK TRK PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.1 | 2.3 | PID INSULIN PATHWAY | Insulin Pathway |
| 0.1 | 1.2 | ST ERK1 ERK2 MAPK PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.1 | 5.1 | PID P75 NTR PATHWAY | p75(NTR)-mediated signaling |
| 0.1 | 0.4 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.1 | 1.8 | PID PS1 PATHWAY | Presenilin action in Notch and Wnt signaling |
| 0.1 | 2.5 | PID ERBB4 PATHWAY | ErbB4 signaling events |
| 0.0 | 2.0 | PID FCER1 PATHWAY | Fc-epsilon receptor I signaling in mast cells |
| 0.0 | 3.3 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.0 | 0.4 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.0 | 0.7 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.0 | 2.6 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.0 | 0.8 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
| 0.0 | 1.2 | PID RET PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.0 | 4.7 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.0 | 1.7 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.0 | 1.2 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.0 | 1.2 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.0 | 1.3 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.0 | 0.2 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.0 | 1.0 | PID FAS PATHWAY | FAS (CD95) signaling pathway |
| 0.0 | 2.3 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.0 | 0.7 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
| 0.0 | 0.1 | PID IL2 STAT5 PATHWAY | IL2 signaling events mediated by STAT5 |
| 0.0 | 0.9 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
| 0.0 | 0.9 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.0 | 0.3 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.0 | 0.6 | PID AURORA A PATHWAY | Aurora A signaling |
| 0.0 | 0.3 | PID IL1 PATHWAY | IL1-mediated signaling events |
| 0.0 | 1.1 | PID E2F PATHWAY | E2F transcription factor network |
| 0.0 | 0.3 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.0 | 0.4 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.0 | 0.2 | SIG PIP3 SIGNALING IN CARDIAC MYOCTES | Genes related to PIP3 signaling in cardiac myocytes |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 4.7 | REACTOME BINDING AND ENTRY OF HIV VIRION | Genes involved in Binding and entry of HIV virion |
| 0.7 | 1.5 | REACTOME ORC1 REMOVAL FROM CHROMATIN | Genes involved in Orc1 removal from chromatin |
| 0.6 | 10.1 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.5 | 11.5 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.5 | 9.1 | REACTOME KERATAN SULFATE DEGRADATION | Genes involved in Keratan sulfate degradation |
| 0.5 | 12.9 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.5 | 6.1 | REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 | Genes involved in IKK complex recruitment mediated by RIP1 |
| 0.4 | 10.5 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.4 | 10.6 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.3 | 6.0 | REACTOME G2 M DNA DAMAGE CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 0.3 | 5.9 | REACTOME MTORC1 MEDIATED SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 0.3 | 4.5 | REACTOME THE ACTIVATION OF ARYLSULFATASES | Genes involved in The activation of arylsulfatases |
| 0.3 | 11.7 | REACTOME RNA POL I TRANSCRIPTION INITIATION | Genes involved in RNA Polymerase I Transcription Initiation |
| 0.3 | 7.6 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.3 | 22.3 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.3 | 11.5 | REACTOME GROWTH HORMONE RECEPTOR SIGNALING | Genes involved in Growth hormone receptor signaling |
| 0.2 | 4.7 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.2 | 3.8 | REACTOME CALNEXIN CALRETICULIN CYCLE | Genes involved in Calnexin/calreticulin cycle |
| 0.2 | 1.9 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.2 | 4.1 | REACTOME ALPHA LINOLENIC ACID ALA METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
| 0.2 | 0.8 | REACTOME LYSOSOME VESICLE BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
| 0.2 | 6.2 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.2 | 6.5 | REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB | Genes involved in PKA-mediated phosphorylation of CREB |
| 0.2 | 6.6 | REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS | Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters |
| 0.2 | 8.1 | REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT | Genes involved in ABC-family proteins mediated transport |
| 0.2 | 2.8 | REACTOME SIGNALING BY NOTCH4 | Genes involved in Signaling by NOTCH4 |
| 0.2 | 6.9 | REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS | Genes involved in Activation of ATR in response to replication stress |
| 0.1 | 2.7 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 0.1 | 2.8 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.1 | 3.2 | REACTOME REGULATORY RNA PATHWAYS | Genes involved in Regulatory RNA pathways |
| 0.1 | 1.3 | REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR | Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR) |
| 0.1 | 4.0 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |
| 0.1 | 4.3 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.1 | 1.2 | REACTOME PLATELET SENSITIZATION BY LDL | Genes involved in Platelet sensitization by LDL |
| 0.1 | 5.3 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.1 | 2.1 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.1 | 0.4 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.1 | 1.8 | REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
| 0.1 | 0.6 | REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX | Genes involved in Association of licensing factors with the pre-replicative complex |
| 0.1 | 2.5 | REACTOME P38MAPK EVENTS | Genes involved in p38MAPK events |
| 0.1 | 3.4 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.1 | 1.7 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.1 | 7.0 | REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE | Genes involved in Cell death signalling via NRAGE, NRIF and NADE |
| 0.1 | 7.5 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.1 | 6.9 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.1 | 0.9 | REACTOME RETROGRADE NEUROTROPHIN SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
| 0.1 | 2.1 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.1 | 3.1 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.1 | 0.7 | REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 | Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1 |
| 0.1 | 2.8 | REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY | Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery |
| 0.1 | 1.3 | REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
| 0.1 | 4.3 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.1 | 0.3 | REACTOME ERKS ARE INACTIVATED | Genes involved in ERKs are inactivated |
| 0.1 | 0.8 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.1 | 1.2 | REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 | Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1 |
| 0.1 | 1.6 | REACTOME DCC MEDIATED ATTRACTIVE SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.1 | 0.6 | REACTOME SIGNAL ATTENUATION | Genes involved in Signal attenuation |
| 0.1 | 7.0 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.1 | 3.0 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.1 | 1.9 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.0 | 1.4 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.0 | 0.8 | REACTOME THE NLRP3 INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 0.0 | 0.8 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.0 | 0.1 | REACTOME SIGNALLING TO P38 VIA RIT AND RIN | Genes involved in Signalling to p38 via RIT and RIN |
| 0.0 | 4.1 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.0 | 1.2 | REACTOME MITOCHONDRIAL TRNA AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
| 0.0 | 1.6 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.0 | 0.3 | REACTOME G ALPHA S SIGNALLING EVENTS | Genes involved in G alpha (s) signalling events |
| 0.0 | 1.5 | REACTOME GPVI MEDIATED ACTIVATION CASCADE | Genes involved in GPVI-mediated activation cascade |
| 0.0 | 1.3 | REACTOME SEMA4D IN SEMAPHORIN SIGNALING | Genes involved in Sema4D in semaphorin signaling |
| 0.0 | 0.3 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
| 0.0 | 1.8 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.0 | 0.7 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.0 | 0.3 | REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS | Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis |
| 0.0 | 1.1 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.0 | 0.6 | REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
| 0.0 | 1.6 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.0 | 1.3 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.0 | 1.4 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.0 | 2.4 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.0 | 0.4 | REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
| 0.0 | 2.5 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.0 | 0.2 | REACTOME CTNNB1 PHOSPHORYLATION CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
| 0.0 | 0.4 | REACTOME ACYL CHAIN REMODELLING OF PC | Genes involved in Acyl chain remodelling of PC |
| 0.0 | 0.7 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.0 | 0.6 | REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
| 0.0 | 2.6 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 0.0 | 0.3 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.0 | 0.6 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
| 0.0 | 0.6 | REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 | Genes involved in Regulation of AMPK activity via LKB1 |
| 0.0 | 1.1 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.0 | 0.6 | REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
| 0.0 | 0.8 | REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |
| 0.0 | 0.5 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
| 0.0 | 0.4 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.0 | 0.7 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.0 | 0.7 | REACTOME MRNA SPLICING MINOR PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
| 0.0 | 0.5 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 0.0 | 5.9 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.0 | 0.6 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.0 | 0.4 | REACTOME HS GAG DEGRADATION | Genes involved in HS-GAG degradation |
| 0.0 | 0.2 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.0 | 0.2 | REACTOME FORMATION OF INCISION COMPLEX IN GG NER | Genes involved in Formation of incision complex in GG-NER |
| 0.0 | 0.5 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.0 | 0.6 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.0 | 0.9 | REACTOME PPARA ACTIVATES GENE EXPRESSION | Genes involved in PPARA Activates Gene Expression |