Project

Inflammatory response time course, HUVEC (Wada et al., 2009)

Navigation
Downloads

Results for MSX2

Z-value: 0.44

Motif logo

Transcription factors associated with MSX2

Gene Symbol Gene ID Gene Info
ENSG00000120149.7 msh homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MSX2hg19_v2_chr5_+_174151536_1741516100.471.7e-02Click!

Activity profile of MSX2 motif

Sorted Z-values of MSX2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_112127981 1.69 ENST00000486726.2
RP11-231E6.1
chr12_-_10022735 1.18 ENST00000228438.2
C-type lectin domain family 2, member B
chr4_-_138453606 0.88 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
protocadherin 18
chr6_-_111927062 0.82 ENST00000359831.4
TRAF3 interacting protein 2
chr5_-_31532160 0.66 ENST00000511367.2
ENST00000513349.1
drosha, ribonuclease type III
chr12_+_9102632 0.61 ENST00000539240.1
killer cell lectin-like receptor subfamily G, member 1
chr6_-_111927449 0.59 ENST00000368761.5
ENST00000392556.4
ENST00000340026.6
TRAF3 interacting protein 2
chr11_-_124981475 0.58 ENST00000532156.1
ENST00000532407.1
ENST00000279968.4
ENST00000527766.1
ENST00000529583.1
ENST00000524373.1
ENST00000527271.1
ENST00000526175.1
ENST00000529609.1
ENST00000533273.1
ENST00000531909.1
ENST00000529530.1
transmembrane protein 218
chr6_+_130339710 0.56 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
l(3)mbt-like 3 (Drosophila)
chr3_-_141747950 0.52 ENST00000497579.1
transcription factor Dp-2 (E2F dimerization partner 2)
chr1_-_94050668 0.42 ENST00000539242.1
breast cancer anti-estrogen resistance 3
chr10_-_105110831 0.41 ENST00000337211.4
polycomb group ring finger 6
chr3_-_151034734 0.41 ENST00000260843.4
G protein-coupled receptor 87
chr10_-_72142345 0.38 ENST00000373224.1
ENST00000446961.1
ENST00000358141.2
ENST00000357631.2
leucine rich repeat containing 20
chr1_-_21377383 0.37 ENST00000374935.3
eukaryotic translation initiation factor 4 gamma, 3
chr10_-_105110890 0.36 ENST00000369847.3
polycomb group ring finger 6
chr12_+_52695617 0.33 ENST00000293525.5
keratin 86
chr7_+_99717230 0.32 ENST00000262932.3
canopy FGF signaling regulator 4
chr19_-_41985048 0.32 ENST00000599801.1
ENST00000595063.1
ENST00000598215.1
AC011526.1
chr19_+_41869894 0.31 ENST00000413014.2
transmembrane protein 91
chr2_-_55646957 0.30 ENST00000263630.8
coiled-coil domain containing 88A
chr20_-_50418947 0.30 ENST00000371539.3
spalt-like transcription factor 4
chr2_-_55647057 0.30 ENST00000436346.1
coiled-coil domain containing 88A
chr8_+_1993152 0.29 ENST00000262113.4
myomesin 2
chr12_-_9102549 0.29 ENST00000000412.3
mannose-6-phosphate receptor (cation dependent)
chr5_+_31532373 0.29 ENST00000325366.9
ENST00000355907.3
ENST00000507818.2
chromosome 5 open reading frame 22
chr20_-_50418972 0.29 ENST00000395997.3
spalt-like transcription factor 4
chr6_-_31830655 0.29 ENST00000375631.4
sialidase 1 (lysosomal sialidase)
chr1_-_68698197 0.28 ENST00000370973.2
ENST00000370971.1
wntless Wnt ligand secretion mediator
chr2_-_89292422 0.26 ENST00000495489.1
immunoglobulin kappa variable 1-8
chr2_-_73460334 0.26 ENST00000258083.2
protease-associated domain containing 1
chr8_+_1993173 0.25 ENST00000523438.1
myomesin 2
chr7_+_91570165 0.25 ENST00000356239.3
ENST00000359028.2
ENST00000358100.2
A kinase (PRKA) anchor protein 9
chr7_+_100209979 0.23 ENST00000493970.1
ENST00000379527.2
motile sperm domain containing 3
chr3_-_114866084 0.22 ENST00000357258.3
zinc finger and BTB domain containing 20
chr4_+_71587669 0.22 ENST00000381006.3
ENST00000226328.4
RUN and FYVE domain containing 3
chr1_-_151431647 0.21 ENST00000368863.2
ENST00000409503.1
ENST00000491586.1
ENST00000533351.1
ENST00000540984.1
pogo transposable element with ZNF domain
chr7_+_100210133 0.21 ENST00000393950.2
ENST00000424091.2
motile sperm domain containing 3
chr17_-_46716647 0.20 ENST00000608940.1
RP11-357H14.17
chr4_-_138453559 0.20 ENST00000511115.1
protocadherin 18
chr1_-_68698222 0.20 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
wntless Wnt ligand secretion mediator
chr3_-_48672859 0.19 ENST00000395550.2
ENST00000455886.2
ENST00000431739.1
ENST00000426599.1
ENST00000383733.3
ENST00000420764.2
ENST00000337000.8
solute carrier family 26 (anion exchanger), member 6
chr7_+_100209725 0.19 ENST00000223054.4
motile sperm domain containing 3
chrX_+_77154935 0.18 ENST00000481445.1
cytochrome c oxidase subunit VIIb
chr15_-_37393406 0.18 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
Meis homeobox 2
chr1_-_151762943 0.18 ENST00000368825.3
ENST00000368823.1
ENST00000458431.2
ENST00000368827.6
ENST00000368824.3
tudor and KH domain containing
chr2_-_89340242 0.18 ENST00000480492.1
immunoglobulin kappa variable 1-12
chr18_+_39535152 0.18 ENST00000262039.4
ENST00000398870.3
ENST00000586545.1
phosphatidylinositol 3-kinase, catalytic subunit type 3
chr1_+_44115814 0.17 ENST00000372396.3
lysine (K)-specific demethylase 4A
chr19_-_47137942 0.17 ENST00000300873.4
guanine nucleotide binding protein (G protein), gamma 8
chr19_+_42817527 0.17 ENST00000598766.1
transmembrane protein 145
chr11_+_17298255 0.16 ENST00000531172.1
ENST00000533738.2
ENST00000323688.6
nucleobindin 2
chr11_+_67250490 0.16 ENST00000528641.2
ENST00000279146.3
aryl hydrocarbon receptor interacting protein
chr11_+_17298297 0.15 ENST00000529010.1
nucleobindin 2
chr1_-_151965048 0.14 ENST00000368809.1
S100 calcium binding protein A10
chr8_+_9413410 0.14 ENST00000520408.1
ENST00000310430.6
ENST00000522110.1
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr7_+_130794846 0.14 ENST00000421797.2
muskelin 1, intracellular mediator containing kelch motifs
chr11_-_102323740 0.14 ENST00000398136.2
transmembrane protein 123
chr17_+_42264556 0.14 ENST00000319511.6
ENST00000589785.1
ENST00000592825.1
ENST00000589184.1
transmembrane and ubiquitin-like domain containing 2
chr19_+_17378278 0.14 ENST00000596335.1
ENST00000601436.1
ENST00000595632.1
BRISC and BRCA1 A complex member 1
chr12_+_28410128 0.14 ENST00000381259.1
ENST00000381256.1
coiled-coil domain containing 91
chr14_+_32798547 0.14 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
A kinase (PRKA) anchor protein 6
chr8_+_38831683 0.13 ENST00000302495.4
HtrA serine peptidase 4
chr1_+_151735431 0.13 ENST00000321531.5
ENST00000315067.8
ornithine decarboxylase antizyme 3
chr11_+_108535752 0.13 ENST00000322536.3
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
chr18_-_44181442 0.13 ENST00000398722.4
lipoxygenase homology domains 1
chr19_+_17378159 0.13 ENST00000598188.1
ENST00000359435.4
ENST00000599474.1
ENST00000599057.1
ENST00000601043.1
ENST00000447614.2
BRISC and BRCA1 A complex member 1
chr11_-_121986923 0.12 ENST00000560104.1
BH3-like motif containing, cell death inducer
chr6_+_160183492 0.12 ENST00000541436.1
acetyl-CoA acetyltransferase 2
chr10_-_99447024 0.12 ENST00000370626.3
arginine vasopressin-induced 1
chr2_+_90248739 0.12 ENST00000468879.1
immunoglobulin kappa variable 1D-43
chr1_-_228613026 0.11 ENST00000366696.1
histone cluster 3, H3
chr1_-_151431909 0.11 ENST00000361398.3
ENST00000271715.2
pogo transposable element with ZNF domain
chr4_-_46996424 0.11 ENST00000264318.3
gamma-aminobutyric acid (GABA) A receptor, alpha 4
chr1_-_36916066 0.11 ENST00000315643.9
organic solute carrier partner 1
chr19_+_4007644 0.11 ENST00000262971.2
protein inhibitor of activated STAT, 4
chr17_+_12569306 0.10 ENST00000425538.1
myocardin
chrX_+_130192318 0.10 ENST00000370922.1
Rho GTPase activating protein 36
chr6_+_53948328 0.10 ENST00000370876.2
muscular LMNA-interacting protein
chr1_-_232651312 0.09 ENST00000262861.4
signal-induced proliferation-associated 1 like 2
chr3_+_186353756 0.09 ENST00000431018.1
ENST00000450521.1
ENST00000539949.1
fetuin B
chr1_+_11714914 0.09 ENST00000425796.1
ENST00000376770.1
ENST00000376768.1
ENST00000251547.5
ENST00000376760.1
ENST00000376762.4
F-box protein 44
chr7_-_99716952 0.08 ENST00000523306.1
ENST00000344095.4
ENST00000417349.1
ENST00000493322.1
ENST00000520135.1
ENST00000418432.2
ENST00000460673.2
ENST00000452041.1
ENST00000452438.2
ENST00000451699.1
ENST00000453269.2
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr7_+_48211048 0.08 ENST00000435803.1
ATP-binding cassette, sub-family A (ABC1), member 13
chr19_-_19249255 0.08 ENST00000587583.2
ENST00000450333.2
ENST00000587096.1
ENST00000162044.9
ENST00000592369.1
ENST00000587915.1
transmembrane protein 161A
chr14_+_39736582 0.08 ENST00000556148.1
ENST00000348007.3
CTAGE family, member 5
chr20_-_50419055 0.08 ENST00000217086.4
spalt-like transcription factor 4
chr12_+_54718904 0.08 ENST00000262061.2
ENST00000549043.1
ENST00000552218.1
ENST00000553231.1
ENST00000552362.1
ENST00000455864.2
ENST00000416254.2
ENST00000549116.1
ENST00000551779.1
coatomer protein complex, subunit zeta 1
chr7_-_99717463 0.07 ENST00000437822.2
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr1_-_36915880 0.07 ENST00000445843.3
organic solute carrier partner 1
chr20_+_49126881 0.06 ENST00000371621.3
ENST00000541713.1
protein tyrosine phosphatase, non-receptor type 1
chr4_-_69434245 0.06 ENST00000317746.2
UDP glucuronosyltransferase 2 family, polypeptide B17
chr15_+_80351910 0.06 ENST00000261749.6
ENST00000561060.1
zinc finger, AN1-type domain 6
chr10_-_99205607 0.06 ENST00000477692.2
ENST00000485122.2
ENST00000370886.5
ENST00000370885.4
ENST00000370902.3
ENST00000370884.5
exosome component 1
chr16_+_58783542 0.06 ENST00000500117.1
ENST00000565722.1
RP11-410D17.2
chr10_-_56561022 0.06 ENST00000373965.2
ENST00000414778.1
ENST00000395438.1
ENST00000409834.1
ENST00000395445.1
ENST00000395446.1
ENST00000395442.1
ENST00000395440.1
ENST00000395432.2
ENST00000361849.3
ENST00000395433.1
ENST00000320301.6
ENST00000395430.1
ENST00000437009.1
protocadherin-related 15
chr20_+_56964169 0.06 ENST00000475243.1
VAMP (vesicle-associated membrane protein)-associated protein B and C
chr14_+_65381079 0.06 ENST00000549115.1
ENST00000607599.1
ENST00000548752.2
ENST00000359118.2
ENST00000552002.2
ENST00000551947.1
ENST00000551093.1
ENST00000542227.1
ENST00000447296.2
ENST00000549987.1
churchill domain containing 1
farnesyltransferase, CAAX box, beta
CHURC1-FNTB readthrough
chr3_-_164796269 0.05 ENST00000264382.3
sucrase-isomaltase (alpha-glucosidase)
chr21_-_32253874 0.05 ENST00000332378.4
keratin associated protein 11-1
chr20_+_54967409 0.05 ENST00000415828.1
ENST00000217109.4
ENST00000428552.1
cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
chr1_-_190446759 0.05 ENST00000367462.3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr2_+_172864490 0.05 ENST00000315796.4
methionyl aminopeptidase type 1D (mitochondrial)
chr6_-_116833500 0.05 ENST00000356128.4
trafficking protein particle complex 3-like
chr12_-_95397442 0.05 ENST00000547157.1
ENST00000547986.1
ENST00000327772.2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
chr5_+_150639360 0.04 ENST00000523004.1
GM2 ganglioside activator
chr5_+_140557371 0.04 ENST00000239444.2
protocadherin beta 8
chr10_-_56560939 0.04 ENST00000373955.1
protocadherin-related 15
chr1_-_23694794 0.04 ENST00000374608.3
zinc finger protein 436
chr1_+_152943122 0.03 ENST00000328051.2
small proline-rich protein 4
chr3_+_140396881 0.03 ENST00000286349.3
tripartite motif containing 42
chr10_-_28571015 0.02 ENST00000375719.3
ENST00000375732.1
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr6_+_25652501 0.02 ENST00000334979.6
secretagogin, EF-hand calcium binding protein
chr12_-_10955226 0.02 ENST00000240687.2
taste receptor, type 2, member 7
chr17_-_38574169 0.02 ENST00000423485.1
topoisomerase (DNA) II alpha 170kDa
chr11_-_71823715 0.02 ENST00000545944.1
ENST00000502597.2
anaphase promoting complex subunit 15
chr9_-_4666421 0.01 ENST00000381895.5
spermatogenesis associated 6-like
chr14_-_23504337 0.01 ENST00000361611.6
proteasome (prosome, macropain) subunit, beta type, 5
chr19_+_11485333 0.01 ENST00000312423.2
SWIM-type zinc finger 7 associated protein 1
chr16_+_53133070 0.01 ENST00000565832.1
chromodomain helicase DNA binding protein 9
chr17_-_10372875 0.01 ENST00000255381.2
myosin, heavy chain 4, skeletal muscle
chrX_+_89176881 0.01 ENST00000283891.5
ENST00000561129.2
TGFB-induced factor homeobox 2-like, X-linked
chr8_+_92261516 0.01 ENST00000276609.3
ENST00000309536.2
solute carrier family 26 (anion exchanger), member 7
chr3_+_113251143 0.01 ENST00000264852.4
ENST00000393830.3
SID1 transmembrane family, member 1
chr17_-_9929581 0.00 ENST00000437099.2
ENST00000396115.2
growth arrest-specific 7
chr19_-_10121144 0.00 ENST00000264828.3
collagen, type V, alpha 3
chrX_+_70752917 0.00 ENST00000373719.3
O-linked N-acetylglucosamine (GlcNAc) transferase
chr9_+_124329336 0.00 ENST00000394340.3
ENST00000436835.1
ENST00000259371.2
DAB2 interacting protein
chr14_-_23504432 0.00 ENST00000425762.2
proteasome (prosome, macropain) subunit, beta type, 5
chr14_+_22670455 0.00 ENST00000390460.1
T cell receptor alpha variable 26-2

Network of associatons between targets according to the STRING database.

First level regulatory network of MSX2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 0.5 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.5 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.1 0.7 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.1 0.2 GO:0042938 dipeptide transport(GO:0042938)
0.0 1.4 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.7 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.6 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.1 GO:1900222 regulation of cell growth by extracellular stimulus(GO:0001560) negative regulation of beta-amyloid clearance(GO:1900222)
0.0 0.3 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.3 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.2 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.2 GO:0051344 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.2 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.1 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.0 0.3 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.4 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.1 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174) positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.4 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.1 GO:2001023 regulation of response to drug(GO:2001023)
0.0 0.5 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.1 GO:0090160 Golgi to lysosome transport(GO:0090160)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.8 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.3 GO:0070552 BRISC complex(GO:0070552)
0.0 0.2 GO:0071547 piP-body(GO:0071547)
0.0 0.6 GO:0032982 myosin filament(GO:0032982)
0.0 0.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.7 GO:1902555 endoribonuclease complex(GO:1902555)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.0 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.2 GO:0015563 uptake transmembrane transporter activity(GO:0015563)
0.0 0.3 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.5 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.1 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.6 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.5 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 0.4 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.4 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.0 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane