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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for MYOD1

Z-value: 0.71

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Transcription factors associated with MYOD1

Gene Symbol Gene ID Gene Info
MYOD1
ENSG00000129152.3 myogenic differentiation 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MYOD1hg19_v2_chr11_+_17741111_17741124-0.067.8e-01Click!

Activity profile of MYOD1 motif

Sorted Z-values of MYOD1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_39382900 8.26 ENST00000377721.3
ENST00000455970.2
KRTAP9-2
keratin associated protein 9-2
chr17_+_39394250 3.31 ENST00000254072.6
KRTAP9-8
keratin associated protein 9-8
chr17_+_68165657 1.61 ENST00000243457.3
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr17_-_42277203 1.23 ENST00000587097.1
ATXN7L3
ataxin 7-like 3
chr22_-_37882395 1.22 ENST00000416983.3
ENST00000424765.2
ENST00000356998.3
MFNG
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr16_-_46864955 1.20 ENST00000565112.1
C16orf87
chromosome 16 open reading frame 87
chr11_-_33891362 1.18 ENST00000395833.3
LMO2
LIM domain only 2 (rhombotin-like 1)
chr15_+_57668695 1.13 ENST00000281282.5
CGNL1
cingulin-like 1
chr5_+_139027877 1.13 ENST00000302517.3
CXXC5
CXXC finger protein 5
chr11_+_128634589 1.11 ENST00000281428.8
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr7_-_120497178 1.11 ENST00000441017.1
ENST00000424710.1
ENST00000433758.1
TSPAN12
tetraspanin 12
chr17_+_4402133 1.09 ENST00000329078.3
SPNS2
spinster homolog 2 (Drosophila)
chr12_+_79258444 0.99 ENST00000261205.4
SYT1
synaptotagmin I
chr12_+_79258547 0.99 ENST00000457153.2
SYT1
synaptotagmin I
chr6_+_30852130 0.95 ENST00000428153.2
ENST00000376568.3
ENST00000452441.1
ENST00000515219.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr6_-_76203345 0.95 ENST00000393004.2
FILIP1
filamin A interacting protein 1
chr3_+_32147997 0.90 ENST00000282541.5
GPD1L
glycerol-3-phosphate dehydrogenase 1-like
chr15_-_70994612 0.89 ENST00000558758.1
ENST00000379983.2
ENST00000560441.1
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr6_+_30851840 0.88 ENST00000511510.1
ENST00000376569.3
ENST00000376575.3
ENST00000376570.4
ENST00000446312.1
ENST00000504927.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr10_+_94608245 0.85 ENST00000443748.2
ENST00000260762.6
EXOC6
exocyst complex component 6
chr3_-_66024213 0.84 ENST00000483466.1
MAGI1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr1_-_55352834 0.84 ENST00000371269.3
DHCR24
24-dehydrocholesterol reductase
chr1_+_61869748 0.83 ENST00000357977.5
NFIA
nuclear factor I/A
chr2_+_173600514 0.82 ENST00000264111.6
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr5_+_139028510 0.81 ENST00000502336.1
ENST00000520967.1
ENST00000511048.1
CXXC5
CXXC finger protein 5
chr2_-_220435963 0.81 ENST00000373876.1
ENST00000404537.1
ENST00000603926.1
ENST00000373873.4
ENST00000289656.3
OBSL1
obscurin-like 1
chr6_-_76203454 0.80 ENST00000237172.7
FILIP1
filamin A interacting protein 1
chr2_-_208489275 0.78 ENST00000272839.3
ENST00000426075.1
METTL21A
methyltransferase like 21A
chr19_-_19051103 0.77 ENST00000542541.2
ENST00000433218.2
HOMER3
homer homolog 3 (Drosophila)
chr1_+_89990431 0.76 ENST00000330947.2
ENST00000358200.4
LRRC8B
leucine rich repeat containing 8 family, member B
chr2_-_175629135 0.75 ENST00000409542.1
ENST00000409219.1
CHRNA1
cholinergic receptor, nicotinic, alpha 1 (muscle)
chr7_-_11871815 0.75 ENST00000423059.4
THSD7A
thrombospondin, type I, domain containing 7A
chr7_+_155090271 0.75 ENST00000476756.1
INSIG1
insulin induced gene 1
chr11_-_2170786 0.74 ENST00000300632.5
IGF2
insulin-like growth factor 2 (somatomedin A)
chr6_+_17281573 0.73 ENST00000379052.5
RBM24
RNA binding motif protein 24
chr8_+_120220561 0.72 ENST00000276681.6
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr3_+_52454971 0.69 ENST00000465863.1
PHF7
PHD finger protein 7
chr8_-_41522719 0.69 ENST00000335651.6
ANK1
ankyrin 1, erythrocytic
chr3_+_9975497 0.68 ENST00000397170.3
ENST00000383811.3
ENST00000452070.1
ENST00000326434.5
CRELD1
cysteine-rich with EGF-like domains 1
chr9_-_79307096 0.66 ENST00000376717.2
ENST00000223609.6
ENST00000443509.2
PRUNE2
prune homolog 2 (Drosophila)
chr6_+_30848557 0.66 ENST00000460944.2
ENST00000324771.8
DDR1
discoidin domain receptor tyrosine kinase 1
chr17_-_8534067 0.65 ENST00000360416.3
ENST00000269243.4
MYH10
myosin, heavy chain 10, non-muscle
chr17_-_8534031 0.65 ENST00000411957.1
ENST00000396239.1
ENST00000379980.4
MYH10
myosin, heavy chain 10, non-muscle
chrX_-_63005405 0.65 ENST00000374878.1
ENST00000437457.2
ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr2_+_173600671 0.64 ENST00000409036.1
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr2_+_173600565 0.64 ENST00000397081.3
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr7_-_132261253 0.64 ENST00000321063.4
PLXNA4
plexin A4
chr6_-_16761678 0.62 ENST00000244769.4
ENST00000436367.1
ATXN1
ataxin 1
chrX_+_86772787 0.61 ENST00000373114.4
KLHL4
kelch-like family member 4
chr1_-_154928562 0.61 ENST00000368463.3
ENST00000539880.1
ENST00000542459.1
ENST00000368460.3
ENST00000368465.1
PBXIP1
pre-B-cell leukemia homeobox interacting protein 1
chr4_+_129732467 0.61 ENST00000413543.2
PHF17
jade family PHD finger 1
chr11_+_33563821 0.59 ENST00000321505.4
ENST00000265654.5
ENST00000389726.3
KIAA1549L
KIAA1549-like
chr3_-_128294929 0.58 ENST00000356020.2
C3orf27
chromosome 3 open reading frame 27
chr16_-_46865286 0.57 ENST00000285697.4
C16orf87
chromosome 16 open reading frame 87
chr16_-_31214051 0.56 ENST00000350605.4
PYCARD
PYD and CARD domain containing
chr1_-_17304771 0.55 ENST00000375534.3
MFAP2
microfibrillar-associated protein 2
chr9_+_90112767 0.55 ENST00000408954.3
DAPK1
death-associated protein kinase 1
chr9_-_13165457 0.53 ENST00000542239.1
ENST00000538841.1
ENST00000433359.2
MPDZ
multiple PDZ domain protein
chr2_-_235405168 0.53 ENST00000339728.3
ARL4C
ADP-ribosylation factor-like 4C
chr10_-_81205373 0.53 ENST00000372336.3
ZCCHC24
zinc finger, CCHC domain containing 24
chr21_-_35899113 0.53 ENST00000492600.1
ENST00000481448.1
ENST00000381132.2
RCAN1
regulator of calcineurin 1
chr11_+_44748361 0.51 ENST00000533202.1
ENST00000533080.1
ENST00000520358.2
ENST00000520999.2
TSPAN18
tetraspanin 18
chr5_+_56111361 0.51 ENST00000399503.3
MAP3K1
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
chr2_+_233404429 0.50 ENST00000389494.3
ENST00000389492.3
CHRNG
cholinergic receptor, nicotinic, gamma (muscle)
chr17_+_26369865 0.50 ENST00000582037.1
NLK
nemo-like kinase
chrX_+_150151824 0.50 ENST00000455596.1
ENST00000448905.2
HMGB3
high mobility group box 3
chr2_-_197041193 0.48 ENST00000409228.1
STK17B
serine/threonine kinase 17b
chr2_-_183387430 0.48 ENST00000410103.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr15_-_75748115 0.48 ENST00000360439.4
SIN3A
SIN3 transcription regulator family member A
chr1_-_33168336 0.47 ENST00000373484.3
SYNC
syncoilin, intermediate filament protein
chr3_+_52828805 0.47 ENST00000416872.2
ENST00000449956.2
ITIH3
inter-alpha-trypsin inhibitor heavy chain 3
chr12_-_27167233 0.47 ENST00000535819.1
ENST00000543803.1
ENST00000535423.1
ENST00000539741.1
ENST00000343028.4
ENST00000545600.1
ENST00000543088.1
TM7SF3
transmembrane 7 superfamily member 3
chr1_+_78354297 0.46 ENST00000334785.7
NEXN
nexilin (F actin binding protein)
chr21_+_46117087 0.46 ENST00000400365.3
KRTAP10-12
keratin associated protein 10-12
chr17_+_58755184 0.45 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
BCAS3
breast carcinoma amplified sequence 3
chr15_-_48937884 0.44 ENST00000560355.1
FBN1
fibrillin 1
chr17_-_46035187 0.44 ENST00000300557.2
PRR15L
proline rich 15-like
chr19_+_48216600 0.44 ENST00000263277.3
ENST00000538399.1
EHD2
EH-domain containing 2
chr8_-_91657740 0.44 ENST00000422900.1
TMEM64
transmembrane protein 64
chr10_-_13043697 0.44 ENST00000378825.3
CCDC3
coiled-coil domain containing 3
chr19_-_18391708 0.44 ENST00000600972.1
JUND
jun D proto-oncogene
chr5_-_94620239 0.43 ENST00000515393.1
MCTP1
multiple C2 domains, transmembrane 1
chr12_-_109221160 0.43 ENST00000326470.5
SSH1
slingshot protein phosphatase 1
chr3_-_141868293 0.42 ENST00000317104.7
ENST00000494358.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr6_+_144904334 0.42 ENST00000367526.4
UTRN
utrophin
chr1_-_935361 0.42 ENST00000484667.2
HES4
hes family bHLH transcription factor 4
chr6_-_31697255 0.41 ENST00000436437.1
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr11_-_31531121 0.41 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMMP1L
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr21_+_17791648 0.41 ENST00000602892.1
ENST00000418813.2
ENST00000435697.1
LINC00478
long intergenic non-protein coding RNA 478
chr12_-_12503156 0.40 ENST00000543314.1
ENST00000396349.3
MANSC1
MANSC domain containing 1
chr19_+_39904168 0.40 ENST00000438123.1
ENST00000409797.2
ENST00000451354.2
PLEKHG2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr3_-_65583561 0.40 ENST00000460329.2
MAGI1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr12_-_50677255 0.40 ENST00000551691.1
ENST00000394943.3
ENST00000341247.4
LIMA1
LIM domain and actin binding 1
chr13_-_99630233 0.40 ENST00000376460.1
ENST00000442173.1
DOCK9
dedicator of cytokinesis 9
chr8_+_81398444 0.39 ENST00000455036.3
ENST00000426744.2
ZBTB10
zinc finger and BTB domain containing 10
chr3_+_54157480 0.39 ENST00000490478.1
CACNA2D3
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr9_-_72287191 0.38 ENST00000265381.4
APBA1
amyloid beta (A4) precursor protein-binding, family A, member 1
chr1_-_150979333 0.37 ENST00000312210.5
FAM63A
family with sequence similarity 63, member A
chr19_-_49658387 0.36 ENST00000595625.1
HRC
histidine rich calcium binding protein
chr19_+_55996565 0.36 ENST00000587400.1
NAT14
N-acetyltransferase 14 (GCN5-related, putative)
chr11_-_66725837 0.35 ENST00000393958.2
ENST00000393960.1
ENST00000524491.1
ENST00000355677.3
PC
pyruvate carboxylase
chr22_+_41075277 0.35 ENST00000381433.2
MCHR1
melanin-concentrating hormone receptor 1
chr3_+_50192499 0.35 ENST00000413852.1
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr19_-_49658641 0.35 ENST00000252825.4
HRC
histidine rich calcium binding protein
chr8_-_29120580 0.35 ENST00000524189.1
KIF13B
kinesin family member 13B
chrX_+_86772707 0.35 ENST00000373119.4
KLHL4
kelch-like family member 4
chrX_-_102565932 0.35 ENST00000372674.1
ENST00000372677.3
BEX2
brain expressed X-linked 2
chrX_+_100333709 0.35 ENST00000372930.4
TMEM35
transmembrane protein 35
chr20_+_42574317 0.35 ENST00000358131.5
TOX2
TOX high mobility group box family member 2
chr18_-_53089723 0.35 ENST00000561992.1
ENST00000562512.2
TCF4
transcription factor 4
chr21_+_17791838 0.35 ENST00000453910.1
LINC00478
long intergenic non-protein coding RNA 478
chr7_+_2687173 0.33 ENST00000403167.1
TTYH3
tweety family member 3
chr6_-_24358264 0.33 ENST00000378454.3
DCDC2
doublecortin domain containing 2
chr20_+_306177 0.33 ENST00000544632.1
SOX12
SRY (sex determining region Y)-box 12
chr2_-_220436248 0.32 ENST00000265318.4
OBSL1
obscurin-like 1
chr9_-_16728161 0.32 ENST00000603713.1
ENST00000603313.1
BNC2
basonuclin 2
chr16_+_3062457 0.32 ENST00000445369.2
CLDN9
claudin 9
chr11_+_31531291 0.32 ENST00000350638.5
ENST00000379163.5
ENST00000395934.2
ELP4
elongator acetyltransferase complex subunit 4
chr4_+_102268904 0.32 ENST00000527564.1
ENST00000529296.1
AP001816.1
Uncharacterized protein
chr19_+_35739782 0.32 ENST00000347609.4
LSR
lipolysis stimulated lipoprotein receptor
chr1_-_150978953 0.31 ENST00000493834.2
FAM63A
family with sequence similarity 63, member A
chr1_+_78354175 0.31 ENST00000401035.3
ENST00000457030.1
ENST00000330010.8
NEXN
nexilin (F actin binding protein)
chr14_-_65346555 0.31 ENST00000542895.1
ENST00000556626.1
SPTB
spectrin, beta, erythrocytic
chr5_-_159739532 0.30 ENST00000520748.1
ENST00000393977.3
ENST00000257536.7
CCNJL
cyclin J-like
chr19_-_38743878 0.30 ENST00000587515.1
PPP1R14A
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr11_-_10829851 0.30 ENST00000532082.1
EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
chr17_-_71088797 0.30 ENST00000580557.1
ENST00000579732.1
ENST00000578620.1
ENST00000542342.2
ENST00000255559.3
ENST00000579018.1
SLC39A11
solute carrier family 39, member 11
chr5_-_81046841 0.30 ENST00000509013.2
ENST00000505980.1
ENST00000509053.1
SSBP2
single-stranded DNA binding protein 2
chr7_+_150065278 0.30 ENST00000519397.1
ENST00000479668.1
ENST00000540729.1
REPIN1
replication initiator 1
chr1_+_154975258 0.30 ENST00000417934.2
ZBTB7B
zinc finger and BTB domain containing 7B
chr22_-_43042955 0.29 ENST00000402438.1
CYB5R3
cytochrome b5 reductase 3
chr3_+_141043050 0.29 ENST00000509842.1
ZBTB38
zinc finger and BTB domain containing 38
chr2_-_175629164 0.29 ENST00000409323.1
ENST00000261007.5
ENST00000348749.5
CHRNA1
cholinergic receptor, nicotinic, alpha 1 (muscle)
chr20_+_43935474 0.29 ENST00000372743.1
ENST00000372741.3
ENST00000343694.3
RBPJL
recombination signal binding protein for immunoglobulin kappa J region-like
chr8_+_81397876 0.29 ENST00000430430.1
ZBTB10
zinc finger and BTB domain containing 10
chr5_-_81046904 0.29 ENST00000515395.1
SSBP2
single-stranded DNA binding protein 2
chr19_+_54371114 0.29 ENST00000448420.1
ENST00000439000.1
ENST00000391770.4
ENST00000391771.1
MYADM
myeloid-associated differentiation marker
chr3_+_111393659 0.29 ENST00000477665.1
PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr2_+_198669365 0.28 ENST00000428675.1
PLCL1
phospholipase C-like 1
chr17_-_14683517 0.28 ENST00000379640.1
AC005863.1
AC005863.1
chr7_-_148580563 0.28 ENST00000476773.1
EZH2
enhancer of zeste homolog 2 (Drosophila)
chr14_-_106967788 0.28 ENST00000390622.2
IGHV1-46
immunoglobulin heavy variable 1-46
chr1_+_6615241 0.27 ENST00000333172.6
ENST00000328191.4
ENST00000351136.3
TAS1R1
taste receptor, type 1, member 1
chr3_-_49851313 0.27 ENST00000333486.3
UBA7
ubiquitin-like modifier activating enzyme 7
chr20_+_42984330 0.27 ENST00000316673.4
ENST00000609795.1
ENST00000457232.1
ENST00000609262.1
HNF4A
hepatocyte nuclear factor 4, alpha
chr9_-_16727978 0.27 ENST00000418777.1
ENST00000468187.2
BNC2
basonuclin 2
chr1_+_162351503 0.27 ENST00000458626.2
C1orf226
chromosome 1 open reading frame 226
chr8_-_66701319 0.27 ENST00000379419.4
PDE7A
phosphodiesterase 7A
chr2_-_219696519 0.27 ENST00000545803.1
ENST00000430489.1
ENST00000392098.3
PRKAG3
protein kinase, AMP-activated, gamma 3 non-catalytic subunit
chr3_+_50192537 0.27 ENST00000002829.3
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chrX_+_150863596 0.27 ENST00000448726.1
ENST00000538575.1
PRRG3
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chr4_-_178363581 0.27 ENST00000264595.2
AGA
aspartylglucosaminidase
chr15_-_37392086 0.27 ENST00000561208.1
MEIS2
Meis homeobox 2
chr13_-_26625169 0.26 ENST00000319420.3
SHISA2
shisa family member 2
chr16_+_58059470 0.26 ENST00000219271.3
MMP15
matrix metallopeptidase 15 (membrane-inserted)
chr11_+_3876859 0.26 ENST00000300737.4
STIM1
stromal interaction molecule 1
chr14_-_55369525 0.26 ENST00000543643.2
ENST00000536224.2
ENST00000395514.1
ENST00000491895.2
GCH1
GTP cyclohydrolase 1
chr3_+_32280159 0.25 ENST00000458535.2
ENST00000307526.3
CMTM8
CKLF-like MARVEL transmembrane domain containing 8
chr1_+_101003687 0.25 ENST00000315033.4
GPR88
G protein-coupled receptor 88
chr2_+_95537170 0.25 ENST00000295201.4
TEKT4
tektin 4
chr2_-_152590946 0.25 ENST00000172853.10
NEB
nebulin
chr12_+_6949964 0.25 ENST00000541978.1
ENST00000435982.2
GNB3
guanine nucleotide binding protein (G protein), beta polypeptide 3
chr3_+_42190714 0.25 ENST00000449246.1
TRAK1
trafficking protein, kinesin binding 1
chr3_+_122513642 0.25 ENST00000261038.5
DIRC2
disrupted in renal carcinoma 2
chr7_-_30029367 0.25 ENST00000242059.5
SCRN1
secernin 1
chr16_+_103816 0.25 ENST00000383018.3
ENST00000417493.1
SNRNP25
small nuclear ribonucleoprotein 25kDa (U11/U12)
chr4_+_170541678 0.24 ENST00000360642.3
ENST00000512813.1
CLCN3
chloride channel, voltage-sensitive 3
chr15_+_32933866 0.24 ENST00000300175.4
ENST00000413748.2
ENST00000494364.1
ENST00000497208.1
SCG5
secretogranin V (7B2 protein)
chr7_-_142120321 0.24 ENST00000390377.1
TRBV7-7
T cell receptor beta variable 7-7
chr1_+_228337553 0.24 ENST00000366714.2
GJC2
gap junction protein, gamma 2, 47kDa
chr12_-_123752624 0.24 ENST00000542174.1
ENST00000535796.1
CDK2AP1
cyclin-dependent kinase 2 associated protein 1
chr11_+_7506713 0.24 ENST00000329293.3
ENST00000534244.1
OLFML1
olfactomedin-like 1
chr11_+_64004888 0.24 ENST00000541681.1
VEGFB
vascular endothelial growth factor B
chr4_+_170541835 0.24 ENST00000504131.2
CLCN3
chloride channel, voltage-sensitive 3
chr5_+_102201687 0.24 ENST00000304400.7
PAM
peptidylglycine alpha-amidating monooxygenase
chr11_+_6411670 0.23 ENST00000530395.1
ENST00000527275.1
SMPD1
sphingomyelin phosphodiesterase 1, acid lysosomal
chr14_-_23822061 0.23 ENST00000397260.3
SLC22A17
solute carrier family 22, member 17
chr2_-_24583583 0.23 ENST00000355123.4
ITSN2
intersectin 2
chr15_+_75335604 0.23 ENST00000563393.1
PPCDC
phosphopantothenoylcysteine decarboxylase
chr4_-_10117949 0.23 ENST00000508079.1
WDR1
WD repeat domain 1
chr2_+_233390890 0.23 ENST00000258385.3
ENST00000536614.1
ENST00000457943.2
CHRND
cholinergic receptor, nicotinic, delta (muscle)
chr17_-_53800217 0.23 ENST00000424486.2
TMEM100
transmembrane protein 100
chr1_-_94312706 0.23 ENST00000370244.1
BCAR3
breast cancer anti-estrogen resistance 3
chr8_-_135522425 0.23 ENST00000521673.1
ZFAT
zinc finger and AT hook domain containing
chr14_-_23822080 0.23 ENST00000397267.1
ENST00000354772.3
SLC22A17
solute carrier family 22, member 17
chr4_-_164534657 0.23 ENST00000339875.5
MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr4_+_169418255 0.23 ENST00000505667.1
ENST00000511948.1
PALLD
palladin, cytoskeletal associated protein
chr14_-_106453155 0.23 ENST00000390594.2
IGHV1-2
immunoglobulin heavy variable 1-2
chr11_-_119252359 0.23 ENST00000455332.2
USP2
ubiquitin specific peptidase 2
chr8_-_91657909 0.22 ENST00000418210.2
TMEM64
transmembrane protein 64
chr8_-_141810634 0.22 ENST00000521986.1
ENST00000523539.1
ENST00000538769.1
PTK2
protein tyrosine kinase 2
chr5_+_102201722 0.22 ENST00000274392.9
ENST00000455264.2
PAM
peptidylglycine alpha-amidating monooxygenase
chr16_-_46865047 0.22 ENST00000394806.2
C16orf87
chromosome 16 open reading frame 87
chr11_+_33279850 0.22 ENST00000531504.1
ENST00000456517.1
HIPK3
homeodomain interacting protein kinase 3
chrX_-_64254587 0.22 ENST00000337990.2
ZC4H2
zinc finger, C4H2 domain containing
chrX_-_70474499 0.22 ENST00000353904.2
ZMYM3
zinc finger, MYM-type 3
chr3_+_182511266 0.22 ENST00000323116.5
ENST00000493826.1
ATP11B
ATPase, class VI, type 11B
chr11_+_6411636 0.22 ENST00000299397.3
ENST00000356761.2
ENST00000342245.4
SMPD1
sphingomyelin phosphodiesterase 1, acid lysosomal
chrX_-_134049233 0.22 ENST00000370779.4
MOSPD1
motile sperm domain containing 1
chr11_-_67120974 0.22 ENST00000539074.1
ENST00000312419.3
POLD4
polymerase (DNA-directed), delta 4, accessory subunit

Network of associatons between targets according to the STRING database.

First level regulatory network of MYOD1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.4 1.6 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.3 1.3 GO:0021592 fourth ventricle development(GO:0021592)
0.3 1.2 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.3 2.5 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.2 0.7 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.2 0.7 GO:1902080 positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.2 1.0 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.2 1.0 GO:0048073 regulation of eye pigmentation(GO:0048073)
0.2 0.6 GO:0021793 chemorepulsion of branchiomotor axon(GO:0021793)
0.2 0.7 GO:0018032 protein amidation(GO:0018032)
0.2 0.6 GO:0002277 myeloid dendritic cell activation involved in immune response(GO:0002277) positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.2 0.8 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.2 0.5 GO:1900075 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
0.2 1.4 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.1 0.4 GO:1904717 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.1 0.5 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.1 0.4 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1 0.7 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.7 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1 0.9 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.1 0.3 GO:1904772 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.1 0.5 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1 0.3 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.1 0.3 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.1 0.7 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 1.0 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.2 GO:0097032 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.1 0.6 GO:0036484 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.1 0.4 GO:0007525 somatic muscle development(GO:0007525)
0.1 1.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.5 GO:0023021 termination of signal transduction(GO:0023021)
0.1 0.3 GO:0061743 motor learning(GO:0061743)
0.1 0.4 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.1 0.2 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.1 0.2 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 0.2 GO:0060720 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.1 0.3 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 0.2 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.1 0.2 GO:0016334 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.1 0.6 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.3 GO:0050917 sensory perception of umami taste(GO:0050917)
0.1 0.8 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 0.2 GO:0015917 aminophospholipid transport(GO:0015917)
0.1 1.3 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.1 0.4 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.1 GO:0007418 ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.0 0.5 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.2 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.0 0.1 GO:0050894 determination of affect(GO:0050894)
0.0 0.2 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.1 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.0 0.1 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.0 1.1 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.2 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
0.0 0.3 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.2 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.7 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.3 GO:0051136 regulation of NK T cell differentiation(GO:0051136)
0.0 0.2 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.0 0.2 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0 0.2 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.0 0.5 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.3 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.3 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.0 0.6 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.3 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.2 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.8 GO:0072189 ureter development(GO:0072189)
0.0 0.4 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 6.5 GO:0031424 keratinization(GO:0031424)
0.0 1.1 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.0 0.2 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.2 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.0 0.3 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.1 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232) cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.0 0.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.4 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.2 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.3 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.0 0.3 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.4 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.2 GO:0009299 mRNA transcription(GO:0009299)
0.0 0.5 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.6 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.3 GO:0030091 protein repair(GO:0030091)
0.0 0.5 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.6 GO:0043586 tongue development(GO:0043586)
0.0 0.7 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.2 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.3 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0015853 adenine transport(GO:0015853)
0.0 0.3 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.1 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.0 0.2 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.1 GO:0009732 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.5 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 1.5 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.1 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.3 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.4 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.1 GO:0051697 protein delipidation(GO:0051697)
0.0 0.0 GO:1903824 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.0 0.0 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.0 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.3 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.1 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 0.2 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.2 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 0.5 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.1 GO:2000567 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.0 0.2 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.4 GO:0002076 osteoblast development(GO:0002076)
0.0 0.3 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.1 GO:0009437 carnitine metabolic process(GO:0009437)
0.0 0.5 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.8 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.0 0.1 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.7 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:0000050 urea cycle(GO:0000050)
0.0 0.1 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.0 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.3 1.3 GO:0097513 myosin II filament(GO:0097513)
0.2 0.7 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.2 1.1 GO:1990393 3M complex(GO:1990393)
0.1 0.4 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.7 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 1.0 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.6 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.1 0.6 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 1.2 GO:0000124 SAGA complex(GO:0000124)
0.1 1.9 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.7 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 4.6 GO:0045095 keratin filament(GO:0045095)
0.1 0.2 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.1 GO:0032173 septin ring(GO:0005940) septin collar(GO:0032173)
0.0 0.2 GO:0042643 actomyosin, actin portion(GO:0042643)
0.0 0.6 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.9 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.4 GO:0070938 contractile ring(GO:0070938)
0.0 0.3 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.5 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.0 1.5 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.2 GO:0035976 AP1 complex(GO:0035976)
0.0 0.5 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.5 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.3 GO:0060091 kinocilium(GO:0060091)
0.0 0.5 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.1 GO:0043291 RAVE complex(GO:0043291)
0.0 0.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.4 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.3 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 1.3 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.3 GO:0008091 spectrin(GO:0008091)
0.0 0.7 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.5 GO:0042599 lamellar body(GO:0042599)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.3 GO:0045120 pronucleus(GO:0045120)
0.0 0.3 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.5 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.1 GO:0043196 varicosity(GO:0043196)
0.0 0.1 GO:0071953 elastic fiber(GO:0071953)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)
0.0 0.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.4 GO:0000421 autophagosome membrane(GO:0000421)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.3 1.9 GO:0030348 syntaxin-3 binding(GO:0030348)
0.3 1.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.2 1.1 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.2 0.7 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.2 0.6 GO:0032090 Pyrin domain binding(GO:0032090)
0.1 0.4 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 0.7 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.6 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.6 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 1.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.5 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 1.9 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.5 GO:0015119 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 0.5 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.2 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.1 0.3 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 0.2 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 1.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.8 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 1.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.2 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.1 0.2 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.1 0.1 GO:0016416 O-palmitoyltransferase activity(GO:0016416)
0.1 0.8 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 1.1 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.3 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.1 GO:0031877 somatostatin receptor binding(GO:0031877)
0.0 0.3 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.2 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.4 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.5 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 1.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.1 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.5 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.4 GO:0004075 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.1 GO:0035514 DNA demethylase activity(GO:0035514)
0.0 0.6 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.3 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.3 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.2 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.5 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.2 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.0 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 1.5 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.1 GO:0005471 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.0 0.3 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.1 GO:0008513 secondary active organic cation transmembrane transporter activity(GO:0008513)
0.0 0.2 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.2 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 1.4 GO:0030552 cAMP binding(GO:0030552)
0.0 0.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0032551 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.7 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.8 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628) peptide antigen binding(GO:0042605)
0.0 0.1 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 1.4 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.5 GO:0043495 protein anchor(GO:0043495)
0.0 0.5 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.3 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.4 GO:0017166 vinculin binding(GO:0017166)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.7 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.1 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.3 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.4 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.8 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
0.0 0.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.9 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.1 GO:0023025 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.0 0.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.1 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.9 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.8 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.3 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.6 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 1.1 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 1.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.3 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.0 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 1.0 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.5 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.5 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.8 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.8 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.5 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.1 1.9 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 1.1 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 2.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.7 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.5 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.1 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.6 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.2 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.4 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.7 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.4 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.3 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.5 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.2 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.6 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.4 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.1 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins