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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for MZF1

Z-value: 0.95

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Transcription factors associated with MZF1

Gene Symbol Gene ID Gene Info
MZF1
ENSG00000099326.4 myeloid zinc finger 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MZF1hg19_v2_chr19_-_59084922_590849470.563.4e-03Click!

Activity profile of MZF1 motif

Sorted Z-values of MZF1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr13_-_72441315 6.45 ENST00000305425.4
ENST00000313174.7
ENST00000354591.4
DACH1
dachshund homolog 1 (Drosophila)
chr13_-_72440901 5.82 ENST00000359684.2
DACH1
dachshund homolog 1 (Drosophila)
chr14_+_24867992 5.07 ENST00000382554.3
NYNRIN
NYN domain and retroviral integrase containing
chr15_-_71055769 3.25 ENST00000539319.1
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chrX_-_70474499 3.03 ENST00000353904.2
ZMYM3
zinc finger, MYM-type 3
chr4_+_41361616 3.01 ENST00000513024.1
LIMCH1
LIM and calponin homology domains 1
chr3_+_8543393 2.43 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
LMCD1
LIM and cysteine-rich domains 1
chr20_+_34742650 2.29 ENST00000373945.1
ENST00000338074.2
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr17_-_47841485 2.13 ENST00000506156.1
ENST00000240364.2
FAM117A
family with sequence similarity 117, member A
chrX_-_70474910 2.13 ENST00000373988.1
ENST00000373998.1
ZMYM3
zinc finger, MYM-type 3
chr17_+_40913264 2.08 ENST00000587142.1
ENST00000588576.1
RAMP2
receptor (G protein-coupled) activity modifying protein 2
chr8_-_81083341 2.00 ENST00000519303.2
TPD52
tumor protein D52
chr3_+_8543561 1.99 ENST00000397386.3
LMCD1
LIM and cysteine-rich domains 1
chr17_+_42634844 1.99 ENST00000315323.3
FZD2
frizzled family receptor 2
chr17_+_40913210 1.86 ENST00000253796.5
RAMP2
receptor (G protein-coupled) activity modifying protein 2
chr14_-_23285069 1.85 ENST00000554758.1
ENST00000397528.4
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr6_-_32191834 1.84 ENST00000375023.3
NOTCH4
notch 4
chr4_+_126237554 1.81 ENST00000394329.3
FAT4
FAT atypical cadherin 4
chr21_+_17961006 1.76 ENST00000602323.1
LINC00478
long intergenic non-protein coding RNA 478
chr20_+_42574317 1.74 ENST00000358131.5
TOX2
TOX high mobility group box family member 2
chr4_+_30721968 1.73 ENST00000361762.2
PCDH7
protocadherin 7
chr1_+_66999799 1.73 ENST00000371035.3
ENST00000371036.3
ENST00000371037.4
SGIP1
SH3-domain GRB2-like (endophilin) interacting protein 1
chr11_-_119234876 1.70 ENST00000525735.1
USP2
ubiquitin specific peptidase 2
chr1_+_66999268 1.70 ENST00000371039.1
ENST00000424320.1
SGIP1
SH3-domain GRB2-like (endophilin) interacting protein 1
chr11_-_2160180 1.68 ENST00000381406.4
IGF2
insulin-like growth factor 2 (somatomedin A)
chr3_+_110790590 1.68 ENST00000485303.1
PVRL3
poliovirus receptor-related 3
chr14_-_23285011 1.68 ENST00000397532.3
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr19_-_38916802 1.66 ENST00000587738.1
RASGRP4
RAS guanyl releasing protein 4
chr5_-_81046841 1.62 ENST00000509013.2
ENST00000505980.1
ENST00000509053.1
SSBP2
single-stranded DNA binding protein 2
chrX_-_135849484 1.61 ENST00000370620.1
ENST00000535227.1
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr12_+_53443963 1.60 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr1_+_221051699 1.54 ENST00000366903.6
HLX
H2.0-like homeobox
chrX_-_119694538 1.53 ENST00000371322.5
CUL4B
cullin 4B
chr20_-_45981138 1.52 ENST00000446994.2
ZMYND8
zinc finger, MYND-type containing 8
chr15_-_71055878 1.51 ENST00000322954.6
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr19_-_14201507 1.48 ENST00000533683.2
SAMD1
sterile alpha motif domain containing 1
chr9_+_2015335 1.40 ENST00000349721.2
ENST00000357248.2
ENST00000450198.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr20_-_39317868 1.39 ENST00000373313.2
MAFB
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
chr5_-_81046904 1.32 ENST00000515395.1
SSBP2
single-stranded DNA binding protein 2
chr12_+_53443680 1.32 ENST00000314250.6
ENST00000451358.1
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr3_+_8543533 1.31 ENST00000454244.1
LMCD1
LIM and cysteine-rich domains 1
chr18_-_72920372 1.28 ENST00000581620.1
ENST00000582437.1
ZADH2
zinc binding alcohol dehydrogenase domain containing 2
chr7_+_114562172 1.26 ENST00000393486.1
ENST00000257724.3
MDFIC
MyoD family inhibitor domain containing
chr10_+_119301928 1.25 ENST00000553456.3
EMX2
empty spiracles homeobox 2
chr14_+_75745477 1.22 ENST00000303562.4
ENST00000554617.1
ENST00000554212.1
ENST00000535987.1
ENST00000555242.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr12_+_79258444 1.20 ENST00000261205.4
SYT1
synaptotagmin I
chrX_-_62974941 1.17 ENST00000374872.1
ENST00000253401.6
ENST00000374870.4
ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr19_-_38916839 1.16 ENST00000433821.2
ENST00000426920.2
ENST00000587753.1
ENST00000454404.2
ENST00000293062.9
RASGRP4
RAS guanyl releasing protein 4
chr18_-_53255766 1.14 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
TCF4
transcription factor 4
chr19_-_38916822 1.13 ENST00000586305.1
RASGRP4
RAS guanyl releasing protein 4
chr1_+_78470530 1.13 ENST00000370763.5
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr12_+_79258547 1.12 ENST00000457153.2
SYT1
synaptotagmin I
chr6_-_32157947 1.11 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr19_+_34745442 1.10 ENST00000299505.6
ENST00000588470.1
ENST00000589583.1
ENST00000588338.2
KIAA0355
KIAA0355
chr9_+_71320557 1.08 ENST00000541509.1
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr17_+_7758374 1.06 ENST00000301599.6
ENST00000574668.1
TMEM88
transmembrane protein 88
chr3_-_171177852 1.06 ENST00000284483.8
ENST00000475336.1
ENST00000357327.5
ENST00000460047.1
ENST00000488470.1
ENST00000470834.1
TNIK
TRAF2 and NCK interacting kinase
chr17_-_49337392 1.06 ENST00000376381.2
ENST00000586178.1
MBTD1
mbt domain containing 1
chrX_-_70473957 1.04 ENST00000373984.3
ENST00000314425.5
ENST00000373982.1
ZMYM3
zinc finger, MYM-type 3
chr2_+_45878790 1.04 ENST00000306156.3
PRKCE
protein kinase C, epsilon
chr8_-_4852494 1.02 ENST00000520002.1
ENST00000602557.1
CSMD1
CUB and Sushi multiple domains 1
chr10_+_35416223 1.01 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
CREM
cAMP responsive element modulator
chr8_+_95907993 0.99 ENST00000523378.1
NDUFAF6
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chrX_-_128657457 0.98 ENST00000371121.3
ENST00000371123.1
ENST00000371122.4
SMARCA1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr17_-_39968855 0.98 ENST00000355468.3
ENST00000590496.1
LEPREL4
leprecan-like 4
chr10_-_126849588 0.97 ENST00000411419.2
CTBP2
C-terminal binding protein 2
chr3_+_9975497 0.96 ENST00000397170.3
ENST00000383811.3
ENST00000452070.1
ENST00000326434.5
CRELD1
cysteine-rich with EGF-like domains 1
chr3_-_169381183 0.96 ENST00000494292.1
MECOM
MDS1 and EVI1 complex locus
chr20_+_34680620 0.95 ENST00000430276.1
ENST00000373950.2
ENST00000452261.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr2_+_61108650 0.93 ENST00000295025.8
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr19_-_11347173 0.93 ENST00000587656.1
DOCK6
dedicator of cytokinesis 6
chr1_+_150337144 0.92 ENST00000539519.1
ENST00000369067.3
ENST00000369068.4
RPRD2
regulation of nuclear pre-mRNA domain containing 2
chr17_-_58469591 0.92 ENST00000589335.1
USP32
ubiquitin specific peptidase 32
chr2_+_61108771 0.91 ENST00000394479.3
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr3_-_168864427 0.91 ENST00000468789.1
MECOM
MDS1 and EVI1 complex locus
chr8_-_4852218 0.90 ENST00000400186.3
ENST00000602723.1
CSMD1
CUB and Sushi multiple domains 1
chr6_+_37321748 0.90 ENST00000373479.4
ENST00000394443.4
RNF8
ring finger protein 8, E3 ubiquitin protein ligase
chr9_+_130830451 0.88 ENST00000373068.2
ENST00000373069.5
SLC25A25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr3_+_194406603 0.88 ENST00000329759.4
FAM43A
family with sequence similarity 43, member A
chr1_-_53018654 0.88 ENST00000257177.4
ENST00000355809.4
ENST00000528642.1
ENST00000470626.1
ENST00000371544.3
ZCCHC11
zinc finger, CCHC domain containing 11
chr11_+_47279504 0.88 ENST00000441012.2
ENST00000437276.1
ENST00000436029.1
ENST00000467728.1
ENST00000405853.3
NR1H3
nuclear receptor subfamily 1, group H, member 3
chr19_+_34287751 0.87 ENST00000590771.1
ENST00000589786.1
ENST00000284006.6
ENST00000588881.1
KCTD15
potassium channel tetramerization domain containing 15
chr12_+_57482877 0.87 ENST00000342556.6
ENST00000357680.4
NAB2
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr2_+_159313452 0.87 ENST00000389757.3
ENST00000389759.3
PKP4
plakophilin 4
chr2_+_219264466 0.87 ENST00000273062.2
CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr15_-_82338460 0.87 ENST00000558133.1
ENST00000329713.4
MEX3B
mex-3 RNA binding family member B
chr1_+_37940153 0.86 ENST00000373087.6
ZC3H12A
zinc finger CCCH-type containing 12A
chr3_-_93692781 0.85 ENST00000394236.3
PROS1
protein S (alpha)
chr2_+_217498105 0.85 ENST00000233809.4
IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr6_+_34857019 0.85 ENST00000360359.3
ENST00000535627.1
ANKS1A
ankyrin repeat and sterile alpha motif domain containing 1A
chr1_+_43766642 0.82 ENST00000372476.3
TIE1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr19_+_10713112 0.82 ENST00000590382.1
ENST00000407327.4
SLC44A2
solute carrier family 44 (choline transporter), member 2
chr6_+_32944119 0.81 ENST00000606059.1
BRD2
bromodomain containing 2
chr17_+_38278530 0.81 ENST00000398532.4
MSL1
male-specific lethal 1 homolog (Drosophila)
chr13_-_110438914 0.81 ENST00000375856.3
IRS2
insulin receptor substrate 2
chr6_-_42016385 0.80 ENST00000502771.1
ENST00000508143.1
ENST00000514588.1
ENST00000510503.1
ENST00000415497.2
ENST00000372988.4
CCND3
cyclin D3
chr1_+_6845578 0.79 ENST00000467404.2
ENST00000439411.2
CAMTA1
calmodulin binding transcription activator 1
chr1_+_32538492 0.78 ENST00000336294.5
TMEM39B
transmembrane protein 39B
chr11_+_86748863 0.77 ENST00000340353.7
TMEM135
transmembrane protein 135
chrX_-_119695279 0.76 ENST00000336592.6
CUL4B
cullin 4B
chrX_-_70474377 0.76 ENST00000373978.1
ENST00000373981.1
ZMYM3
zinc finger, MYM-type 3
chr6_+_148663729 0.76 ENST00000367467.3
SASH1
SAM and SH3 domain containing 1
chr19_-_14316980 0.75 ENST00000361434.3
ENST00000340736.6
LPHN1
latrophilin 1
chr1_-_36022979 0.75 ENST00000469892.1
ENST00000325722.3
KIAA0319L
KIAA0319-like
chr11_+_64002292 0.75 ENST00000426086.2
VEGFB
vascular endothelial growth factor B
chr14_+_75746340 0.75 ENST00000555686.1
ENST00000555672.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr2_+_173686303 0.74 ENST00000397087.3
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr16_-_28222797 0.74 ENST00000569951.1
ENST00000565698.1
XPO6
exportin 6
chr8_-_89339705 0.73 ENST00000286614.6
MMP16
matrix metallopeptidase 16 (membrane-inserted)
chr12_+_57482665 0.73 ENST00000300131.3
NAB2
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr4_+_88928777 0.72 ENST00000237596.2
PKD2
polycystic kidney disease 2 (autosomal dominant)
chr13_+_36050881 0.72 ENST00000537702.1
NBEA
neurobeachin
chr8_-_103668114 0.71 ENST00000285407.6
KLF10
Kruppel-like factor 10
chr1_+_93913665 0.70 ENST00000271234.7
ENST00000370256.4
ENST00000260506.8
FNBP1L
formin binding protein 1-like
chr8_+_29952914 0.69 ENST00000321250.8
ENST00000518001.1
ENST00000520682.1
ENST00000442880.2
ENST00000523116.1
LEPROTL1
leptin receptor overlapping transcript-like 1
chr19_-_6459746 0.69 ENST00000301454.4
ENST00000334510.5
SLC25A23
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
chr14_-_23822061 0.68 ENST00000397260.3
SLC22A17
solute carrier family 22, member 17
chr6_-_110500905 0.68 ENST00000392587.2
WASF1
WAS protein family, member 1
chr6_-_42946947 0.67 ENST00000304611.8
PEX6
peroxisomal biogenesis factor 6
chr6_-_52860171 0.67 ENST00000370963.4
GSTA4
glutathione S-transferase alpha 4
chr11_-_66445219 0.67 ENST00000525754.1
ENST00000531969.1
ENST00000524637.1
ENST00000531036.2
ENST00000310046.4
RBM4B
RNA binding motif protein 4B
chr14_-_23822080 0.67 ENST00000397267.1
ENST00000354772.3
SLC22A17
solute carrier family 22, member 17
chr1_+_32538520 0.66 ENST00000438825.1
ENST00000456834.2
ENST00000373634.4
ENST00000427288.1
TMEM39B
transmembrane protein 39B
chr18_+_46065393 0.65 ENST00000256413.3
CTIF
CBP80/20-dependent translation initiation factor
chr11_-_57283159 0.64 ENST00000533263.1
ENST00000278426.3
SLC43A1
solute carrier family 43 (amino acid system L transporter), member 1
chr18_+_46065483 0.64 ENST00000382998.4
CTIF
CBP80/20-dependent translation initiation factor
chr19_-_41859814 0.64 ENST00000221930.5
TGFB1
transforming growth factor, beta 1
chr7_+_114562616 0.64 ENST00000448022.1
MDFIC
MyoD family inhibitor domain containing
chr11_-_124632179 0.63 ENST00000278927.5
ENST00000442070.2
ENST00000444566.1
ENST00000435477.1
ESAM
endothelial cell adhesion molecule
chrX_+_102883887 0.63 ENST00000372625.3
ENST00000372624.3
TCEAL1
transcription elongation factor A (SII)-like 1
chr17_-_42277203 0.63 ENST00000587097.1
ATXN7L3
ataxin 7-like 3
chr14_+_29241910 0.63 ENST00000399387.4
ENST00000552957.1
ENST00000548213.1
C14orf23
chromosome 14 open reading frame 23
chr11_-_130184555 0.62 ENST00000525842.1
ZBTB44
zinc finger and BTB domain containing 44
chr16_+_29827832 0.62 ENST00000609618.1
PAGR1
PAXIP1-associated glutamate-rich protein 1
chr20_+_306177 0.62 ENST00000544632.1
SOX12
SRY (sex determining region Y)-box 12
chr17_-_62915574 0.61 ENST00000339474.5
ENST00000581368.1
LRRC37A3
leucine rich repeat containing 37, member A3
chr12_-_48152611 0.61 ENST00000389212.3
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr17_-_7166500 0.61 ENST00000575313.1
ENST00000397317.4
CLDN7
claudin 7
chrX_+_73641286 0.60 ENST00000587091.1
SLC16A2
solute carrier family 16, member 2 (thyroid hormone transporter)
chr17_+_4618734 0.60 ENST00000571206.1
ARRB2
arrestin, beta 2
chr3_-_39196049 0.59 ENST00000514182.1
CSRNP1
cysteine-serine-rich nuclear protein 1
chr8_+_29953163 0.58 ENST00000518192.1
LEPROTL1
leptin receptor overlapping transcript-like 1
chr19_+_13051206 0.58 ENST00000586760.1
CALR
calreticulin
chr19_-_14201776 0.58 ENST00000269724.5
SAMD1
sterile alpha motif domain containing 1
chr6_-_32077078 0.58 ENST00000479795.1
TNXB
tenascin XB
chr12_-_48152853 0.58 ENST00000171000.4
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr17_-_48943706 0.56 ENST00000499247.2
TOB1
transducer of ERBB2, 1
chr1_+_6845497 0.56 ENST00000473578.1
ENST00000557126.1
CAMTA1
calmodulin binding transcription activator 1
chr11_+_63448955 0.56 ENST00000377819.5
ENST00000339997.4
ENST00000540798.1
ENST00000545432.1
ENST00000543552.1
ENST00000537981.1
RTN3
reticulon 3
chr2_-_216300784 0.55 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
FN1
fibronectin 1
chr2_+_33172012 0.54 ENST00000404816.2
LTBP1
latent transforming growth factor beta binding protein 1
chr4_+_129730947 0.54 ENST00000452328.2
ENST00000504089.1
PHF17
jade family PHD finger 1
chr17_+_7211656 0.54 ENST00000416016.2
EIF5A
eukaryotic translation initiation factor 5A
chr11_+_47291193 0.53 ENST00000428807.1
ENST00000402799.1
ENST00000406482.1
ENST00000349238.3
ENST00000311027.5
ENST00000407859.3
ENST00000395344.3
ENST00000444117.1
MADD
MAP-kinase activating death domain
chr2_-_217236750 0.52 ENST00000273067.4
MARCH4
membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
chr19_-_46272462 0.52 ENST00000317578.6
SIX5
SIX homeobox 5
chr9_-_86432547 0.52 ENST00000376365.3
ENST00000376371.2
GKAP1
G kinase anchoring protein 1
chr6_+_37321823 0.52 ENST00000487950.1
ENST00000469731.1
RNF8
ring finger protein 8, E3 ubiquitin protein ligase
chr16_-_49890016 0.51 ENST00000563137.2
ZNF423
zinc finger protein 423
chr17_-_36956155 0.51 ENST00000269554.3
PIP4K2B
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
chr2_+_203241531 0.51 ENST00000374580.4
BMPR2
bone morphogenetic protein receptor, type II (serine/threonine kinase)
chr11_+_64001962 0.51 ENST00000309422.2
VEGFB
vascular endothelial growth factor B
chr17_+_4613776 0.51 ENST00000269260.2
ARRB2
arrestin, beta 2
chr5_-_90679145 0.51 ENST00000265138.3
ARRDC3
arrestin domain containing 3
chr11_+_63448918 0.50 ENST00000341307.2
ENST00000356000.3
ENST00000542238.1
RTN3
reticulon 3
chr1_+_97188188 0.50 ENST00000541987.1
PTBP2
polypyrimidine tract binding protein 2
chr1_+_162602244 0.50 ENST00000367922.3
ENST00000367921.3
DDR2
discoidin domain receptor tyrosine kinase 2
chr17_+_4613918 0.50 ENST00000574954.1
ENST00000346341.2
ENST00000572457.1
ENST00000381488.6
ENST00000412477.3
ENST00000571428.1
ENST00000575877.1
ARRB2
arrestin, beta 2
chr9_-_34376851 0.49 ENST00000297625.7
KIAA1161
KIAA1161
chr11_-_130184470 0.49 ENST00000357899.4
ENST00000397753.1
ZBTB44
zinc finger and BTB domain containing 44
chr1_-_8585945 0.49 ENST00000377464.1
RERE
arginine-glutamic acid dipeptide (RE) repeats
chr1_+_178694300 0.49 ENST00000367635.3
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr4_+_129730779 0.49 ENST00000226319.6
PHF17
jade family PHD finger 1
chr8_-_38126635 0.49 ENST00000529359.1
PPAPDC1B
phosphatidic acid phosphatase type 2 domain containing 1B
chr1_+_211432593 0.48 ENST00000367006.4
RCOR3
REST corepressor 3
chr1_+_150337100 0.47 ENST00000401000.4
RPRD2
regulation of nuclear pre-mRNA domain containing 2
chr2_+_16080659 0.47 ENST00000281043.3
MYCN
v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
chr11_-_67210930 0.47 ENST00000453768.2
ENST00000545016.1
ENST00000341356.5
CORO1B
coronin, actin binding protein, 1B
chr1_+_27022839 0.47 ENST00000457599.2
ARID1A
AT rich interactive domain 1A (SWI-like)
chr1_-_154928562 0.46 ENST00000368463.3
ENST00000539880.1
ENST00000542459.1
ENST00000368460.3
ENST00000368465.1
PBXIP1
pre-B-cell leukemia homeobox interacting protein 1
chr12_-_48152428 0.46 ENST00000449771.2
ENST00000395358.3
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr17_+_2240775 0.46 ENST00000268989.3
ENST00000426855.2
SGSM2
small G protein signaling modulator 2
chr19_+_39904168 0.45 ENST00000438123.1
ENST00000409797.2
ENST00000451354.2
PLEKHG2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chrX_+_54834791 0.45 ENST00000218439.4
ENST00000375058.1
ENST00000375060.1
MAGED2
melanoma antigen family D, 2
chr6_+_32936353 0.45 ENST00000374825.4
BRD2
bromodomain containing 2
chr3_-_114343039 0.45 ENST00000481632.1
ZBTB20
zinc finger and BTB domain containing 20
chr6_+_35227449 0.45 ENST00000373953.3
ENST00000440666.2
ENST00000339411.5
ZNF76
zinc finger protein 76
chr12_-_49259643 0.44 ENST00000309739.5
RND1
Rho family GTPase 1
chr19_-_36523709 0.44 ENST00000592017.1
ENST00000360535.4
CLIP3
CAP-GLY domain containing linker protein 3
chr19_-_12721616 0.44 ENST00000311437.6
ZNF490
zinc finger protein 490
chr14_+_66975213 0.44 ENST00000543237.1
ENST00000305960.9
GPHN
gephyrin
chr9_+_17134980 0.44 ENST00000380647.3
CNTLN
centlein, centrosomal protein
chr3_-_105587879 0.44 ENST00000264122.4
ENST00000403724.1
ENST00000405772.1
CBLB
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr7_+_8008418 0.43 ENST00000223145.5
GLCCI1
glucocorticoid induced transcript 1
chr12_+_6875519 0.43 ENST00000389462.4
ENST00000540874.1
ENST00000309083.6
PTMS
parathymosin
chrX_+_70521584 0.43 ENST00000373829.3
ENST00000538820.1
ITGB1BP2
integrin beta 1 binding protein (melusin) 2
chr12_-_57824739 0.43 ENST00000347140.3
ENST00000402412.1
R3HDM2
R3H domain containing 2
chrX_+_134654540 0.43 ENST00000370752.4
DDX26B
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr12_+_56915776 0.43 ENST00000550726.1
ENST00000542360.1
RBMS2
RNA binding motif, single stranded interacting protein 2
chr1_-_221915418 0.43 ENST00000323825.3
ENST00000366899.3
DUSP10
dual specificity phosphatase 10

Network of associatons between targets according to the STRING database.

First level regulatory network of MZF1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 12.3 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.8 2.3 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.6 3.5 GO:1990822 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.5 0.5 GO:2000137 negative regulation of cell proliferation involved in heart morphogenesis(GO:2000137)
0.5 1.4 GO:0035284 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.4 3.9 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.4 1.6 GO:0030822 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.4 5.1 GO:0015074 DNA integration(GO:0015074)
0.4 1.5 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.3 3.4 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.3 1.6 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.3 0.9 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.3 0.9 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.3 1.4 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.3 1.6 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.3 1.6 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.3 1.5 GO:1903758 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.2 0.7 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.2 0.7 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.2 5.7 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.2 0.6 GO:0052552 negative regulation of extracellular matrix disassembly(GO:0010716) induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528) negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.2 0.8 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.2 1.7 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.2 1.7 GO:0003150 muscular septum morphogenesis(GO:0003150)
0.2 1.3 GO:0071461 cellular response to redox state(GO:0071461)
0.2 1.7 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.2 0.5 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.2 1.3 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.2 1.4 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.2 0.5 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.2 0.5 GO:0035669 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.2 1.3 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.2 0.5 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.2 0.8 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.2 1.4 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.2 0.6 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.1 0.4 GO:0042040 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.1 0.6 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.1 2.0 GO:0009629 response to gravity(GO:0009629)
0.1 1.3 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.1 1.3 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.1 GO:0048850 hypophysis morphogenesis(GO:0048850)
0.1 0.7 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408)
0.1 0.8 GO:0010746 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.1 1.4 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 2.3 GO:0070914 UV-damage excision repair(GO:0070914)
0.1 0.5 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.1 0.5 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.1 1.6 GO:0045475 locomotor rhythm(GO:0045475)
0.1 1.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.3 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.1 0.5 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.1 1.9 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.1 1.6 GO:0015866 ADP transport(GO:0015866)
0.1 4.1 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.1 1.0 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.1 0.3 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.1 0.3 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1 0.3 GO:0043049 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.1 0.6 GO:1901164 peptide antigen assembly with MHC protein complex(GO:0002501) negative regulation of trophoblast cell migration(GO:1901164)
0.1 0.3 GO:0032203 telomere formation via telomerase(GO:0032203)
0.1 0.3 GO:0042727 flavin-containing compound biosynthetic process(GO:0042727)
0.1 0.5 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.3 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 0.5 GO:0050915 sensory perception of sour taste(GO:0050915)
0.1 0.4 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1 0.9 GO:0000733 DNA strand renaturation(GO:0000733)
0.1 0.4 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 0.4 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.1 0.3 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 0.3 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
0.1 0.2 GO:0021816 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.1 1.3 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.1 1.1 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 0.3 GO:0051697 protein delipidation(GO:0051697)
0.1 0.7 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.4 GO:0042335 cuticle development(GO:0042335)
0.1 0.3 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.1 0.4 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.1 0.3 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.1 0.2 GO:1904245 regulation of polynucleotide adenylyltransferase activity(GO:1904245) positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.1 0.2 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.1 0.5 GO:1903751 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.1 0.7 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.1 0.2 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.1 4.7 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.1 0.2 GO:0061010 gall bladder development(GO:0061010)
0.1 0.2 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.1 0.3 GO:1902965 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.1 0.3 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.1 0.3 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.1 2.7 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 0.1 GO:1904954 canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.1 0.3 GO:0007386 compartment pattern specification(GO:0007386)
0.0 1.2 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.1 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.0 0.1 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.3 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.0 0.1 GO:0060585 nitric oxide transport(GO:0030185) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0 0.2 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.2 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 1.5 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.2 GO:0002572 pro-T cell differentiation(GO:0002572)
0.0 0.3 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.1 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.2 GO:0061143 alveolar primary septum development(GO:0061143)
0.0 0.1 GO:0015670 carbon dioxide transport(GO:0015670) dipeptide transport(GO:0042938)
0.0 0.3 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0 0.8 GO:0015871 choline transport(GO:0015871)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.9 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.7 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.6 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:2000015 regulation of determination of dorsal identity(GO:2000015)
0.0 0.1 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.1 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.0 0.5 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.4 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.4 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.0 0.1 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.0 0.1 GO:0009405 pathogenesis(GO:0009405) negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.0 0.4 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.0 0.4 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0007418 ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.0 0.1 GO:0034959 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.1 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.0 0.2 GO:0048749 compound eye development(GO:0048749)
0.0 0.2 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029)
0.0 0.5 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.1 GO:0060661 male genitalia morphogenesis(GO:0048808) submandibular salivary gland formation(GO:0060661) hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338) male anatomical structure morphogenesis(GO:0090598)
0.0 2.1 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.0 0.9 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.2 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.3 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.4 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 1.0 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.7 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.3 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.1 GO:0061428 peptidyl-aspartic acid hydroxylation(GO:0042264) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.0 0.4 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.1 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.0 0.1 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.0 0.2 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.2 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 1.8 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.4 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.4 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.3 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.1 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.0 0.3 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.5 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.1 GO:1901093 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.0 0.2 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.1 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 1.0 GO:0006692 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.0 0.4 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.5 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.6 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 0.1 GO:0070295 renal water absorption(GO:0070295)
0.0 0.2 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.3 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.0 0.4 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.4 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.7 GO:0032094 response to food(GO:0032094)
0.0 0.2 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0 0.7 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.4 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.7 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.1 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.1 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.0 0.4 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.3 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.3 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.4 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.2 GO:0021860 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.3 GO:0003416 endochondral bone growth(GO:0003416)
0.0 0.7 GO:0045026 plasma membrane fusion(GO:0045026)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.0 GO:0098838 reduced folate transmembrane transport(GO:0098838)
0.0 0.2 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 0.0 GO:0070101 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588) detection of peptidoglycan(GO:0032499) positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.0 0.3 GO:0071888 macrophage apoptotic process(GO:0071888)
0.0 0.4 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.5 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.4 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.2 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.6 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.0 0.2 GO:0035246 peptidyl-arginine N-methylation(GO:0035246)
0.0 0.3 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 2.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0043606 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 1.0 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 0.3 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.1 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.8 GO:0046626 regulation of insulin receptor signaling pathway(GO:0046626)
0.0 0.2 GO:2000811 negative regulation of anoikis(GO:2000811)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.2 GO:0033630 positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.0 1.5 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.1 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.9 GO:0006446 regulation of translational initiation(GO:0006446)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.9 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.5 2.3 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.3 2.3 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.3 2.1 GO:0035976 AP1 complex(GO:0035976)
0.2 0.7 GO:0070435 Shc-EGFR complex(GO:0070435)
0.1 3.5 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 1.1 GO:0072487 MSL complex(GO:0072487)
0.1 0.9 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 1.4 GO:0097470 ribbon synapse(GO:0097470)
0.1 0.5 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.1 0.3 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
0.1 1.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.4 GO:0044308 axonal spine(GO:0044308)
0.1 2.1 GO:0071564 npBAF complex(GO:0071564)
0.1 0.8 GO:0016589 NURF complex(GO:0016589)
0.1 0.7 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.3 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.8 GO:0071953 elastic fiber(GO:0071953)
0.1 0.6 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.1 0.8 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 1.4 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 0.9 GO:0000124 SAGA complex(GO:0000124)
0.1 0.2 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.0 1.7 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.5 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.3 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.2 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.0 0.7 GO:0045180 basal cortex(GO:0045180)
0.0 0.7 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 2.0 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.1 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 3.8 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.3 GO:1990812 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.0 0.4 GO:0032039 integrator complex(GO:0032039)
0.0 0.4 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 1.5 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 0.2 GO:0097443 sorting endosome(GO:0097443)
0.0 0.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.9 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.1 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.4 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 10.9 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.4 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 1.2 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.6 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 1.5 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.3 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 1.3 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.1 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.3 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.3 GO:0071682 endocytic vesicle lumen(GO:0071682)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 12.3 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.6 3.9 GO:0097643 amylin receptor activity(GO:0097643)
0.5 1.6 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.4 2.3 GO:0030348 syntaxin-3 binding(GO:0030348)
0.4 1.1 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.2 3.5 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.2 0.9 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.2 1.3 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.2 1.0 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.2 1.4 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.2 1.3 GO:0047522 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.2 0.7 GO:0048763 HLH domain binding(GO:0043398) calcium-induced calcium release activity(GO:0048763)
0.2 0.5 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) 1-phosphatidylinositol-3-phosphate 4-kinase activity(GO:0052811)
0.2 0.9 GO:0032810 sterol response element binding(GO:0032810)
0.2 0.5 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.2 3.5 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 0.4 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.1 0.4 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 1.6 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.5 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.1 0.7 GO:0097001 ceramide binding(GO:0097001)
0.1 1.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.5 GO:0050436 microfibril binding(GO:0050436)
0.1 1.8 GO:0030957 Tat protein binding(GO:0030957)
0.1 0.9 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.4 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 1.0 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.7 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 0.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 1.6 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 0.8 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 1.1 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 1.0 GO:0036310 annealing helicase activity(GO:0036310)
0.1 0.9 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.6 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 1.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.8 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.6 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.5 GO:0098821 BMP receptor activity(GO:0098821)
0.1 0.3 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.1 2.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 0.1 GO:0005119 smoothened binding(GO:0005119)
0.1 0.4 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.5 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.3 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 0.9 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.3 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.3 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0 0.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.3 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.4 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.3 GO:0097108 hedgehog family protein binding(GO:0097108)
0.0 2.3 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.5 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 0.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.3 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.3 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.8 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.0 0.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.3 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.3 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 0.3 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 1.2 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.8 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0051766 inositol trisphosphate kinase activity(GO:0051766)
0.0 0.1 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 0.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.3 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 1.5 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.4 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.4 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.3 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.3 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.2 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.1 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 1.3 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.3 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.2 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.5 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.2 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.4 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.2 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.0 0.1 GO:0005046 KDEL sequence binding(GO:0005046)
0.0 0.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 2.1 GO:0003684 damaged DNA binding(GO:0003684)
0.0 6.4 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 2.4 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.2 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 2.1 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.0 GO:0031893 vasopressin receptor binding(GO:0031893)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.0 GO:0017129 triglyceride binding(GO:0017129)
0.0 0.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.0 GO:0008518 reduced folate carrier activity(GO:0008518)
0.0 0.5 GO:0005123 death receptor binding(GO:0005123)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.2 GO:0015266 protein channel activity(GO:0015266) BH3 domain binding(GO:0051434)
0.0 0.3 GO:0048156 tau protein binding(GO:0048156)
0.0 0.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.9 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.7 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.5 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 2.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.0 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.3 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224)
0.0 0.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 0.5 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.5 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.1 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.1 GO:0005497 androgen binding(GO:0005497)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 3.0 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 1.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 1.7 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 3.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 1.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 2.9 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 2.6 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.1 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.4 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 1.8 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.4 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.3 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.5 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.2 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.8 PID EPO PATHWAY EPO signaling pathway
0.0 0.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.8 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.3 PID ATM PATHWAY ATM pathway
0.0 0.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.6 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.6 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 2.6 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.1 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.4 PID CD40 PATHWAY CD40/CD40L signaling
0.0 1.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.3 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.9 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 3.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.8 PID RB 1PATHWAY Regulation of retinoblastoma protein

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 2.3 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 2.0 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 2.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 3.5 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 1.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 0.9 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 1.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 3.4 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.1 0.7 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 1.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.4 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.9 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 1.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.6 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.4 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 3.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.3 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.5 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.5 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.7 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 1.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.7 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 1.7 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.7 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 1.7 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.7 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.4 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.2 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.0 0.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.7 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.0 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.3 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.4 REACTOME KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.1 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.4 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.0 0.4 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.2 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 1.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway