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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for NFATC1

Z-value: 0.43

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Transcription factors associated with NFATC1

Gene Symbol Gene ID Gene Info
NFATC1
ENSG00000131196.13 nuclear factor of activated T cells 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFATC1hg19_v2_chr18_+_77155856_771559390.395.1e-02Click!

Activity profile of NFATC1 motif

Sorted Z-values of NFATC1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_92413353 1.16 ENST00000556154.1
FBLN5
fibulin 5
chr4_+_41614909 0.98 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1
LIM and calponin homology domains 1
chr10_+_94590910 0.94 ENST00000371547.4
EXOC6
exocyst complex component 6
chr21_-_35899113 0.75 ENST00000492600.1
ENST00000481448.1
ENST00000381132.2
RCAN1
regulator of calcineurin 1
chr1_+_61548225 0.58 ENST00000371187.3
NFIA
nuclear factor I/A
chr6_+_132891461 0.55 ENST00000275198.1
TAAR6
trace amine associated receptor 6
chr13_+_32838801 0.53 ENST00000542859.1
FRY
furry homolog (Drosophila)
chr18_+_77155856 0.50 ENST00000253506.5
ENST00000591814.1
NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr4_-_186733363 0.50 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
SORBS2
sorbin and SH3 domain containing 2
chr1_+_61547405 0.50 ENST00000371189.4
NFIA
nuclear factor I/A
chr14_-_92413727 0.45 ENST00000267620.10
FBLN5
fibulin 5
chr9_-_14314518 0.45 ENST00000397581.2
NFIB
nuclear factor I/B
chr1_+_61548374 0.44 ENST00000485903.2
ENST00000371185.2
ENST00000371184.2
NFIA
nuclear factor I/A
chr9_-_14314566 0.43 ENST00000397579.2
NFIB
nuclear factor I/B
chr18_-_22932080 0.41 ENST00000584787.1
ENST00000361524.3
ENST00000538137.2
ZNF521
zinc finger protein 521
chr21_-_27945562 0.39 ENST00000299340.4
ENST00000435845.2
CYYR1
cysteine/tyrosine-rich 1
chr3_-_141747439 0.39 ENST00000467667.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr1_-_160924589 0.35 ENST00000368029.3
ITLN2
intelectin 2
chr12_-_7848364 0.35 ENST00000329913.3
GDF3
growth differentiation factor 3
chr14_+_63671577 0.32 ENST00000555125.1
RHOJ
ras homolog family member J
chr8_-_17555164 0.32 ENST00000297488.6
MTUS1
microtubule associated tumor suppressor 1
chr1_+_82266053 0.32 ENST00000370715.1
ENST00000370713.1
ENST00000319517.6
ENST00000370717.2
ENST00000394879.1
ENST00000271029.4
ENST00000335786.5
LPHN2
latrophilin 2
chr18_+_77155942 0.32 ENST00000397790.2
NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr9_-_16870704 0.31 ENST00000380672.4
ENST00000380667.2
ENST00000380666.2
ENST00000486514.1
BNC2
basonuclin 2
chr3_-_141747459 0.28 ENST00000477292.1
ENST00000478006.1
ENST00000495310.1
ENST00000486111.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr12_+_93771659 0.28 ENST00000337179.5
ENST00000415493.2
NUDT4
nudix (nucleoside diphosphate linked moiety X)-type motif 4
chr3_+_152017924 0.27 ENST00000465907.2
ENST00000492948.1
ENST00000485509.1
ENST00000464596.1
MBNL1
muscleblind-like splicing regulator 1
chrX_+_41193407 0.26 ENST00000457138.2
ENST00000441189.2
DDX3X
DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
chrX_-_63005405 0.25 ENST00000374878.1
ENST00000437457.2
ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr14_+_63671105 0.25 ENST00000316754.3
RHOJ
ras homolog family member J
chr12_-_91573132 0.25 ENST00000550563.1
ENST00000546370.1
DCN
decorin
chr16_-_66952779 0.24 ENST00000570262.1
ENST00000394055.3
ENST00000299752.4
CDH16
cadherin 16, KSP-cadherin
chr11_+_65190245 0.24 ENST00000499732.1
ENST00000501122.2
ENST00000601801.1
NEAT1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr5_+_135394840 0.24 ENST00000503087.1
TGFBI
transforming growth factor, beta-induced, 68kDa
chr1_+_66999799 0.23 ENST00000371035.3
ENST00000371036.3
ENST00000371037.4
SGIP1
SH3-domain GRB2-like (endophilin) interacting protein 1
chr3_+_25469724 0.23 ENST00000437042.2
RARB
retinoic acid receptor, beta
chr16_-_66952742 0.23 ENST00000565235.2
ENST00000568632.1
ENST00000565796.1
CDH16
cadherin 16, KSP-cadherin
chr14_-_89883412 0.23 ENST00000557258.1
FOXN3
forkhead box N3
chr12_-_50616122 0.23 ENST00000552823.1
ENST00000552909.1
LIMA1
LIM domain and actin binding 1
chr5_-_111093759 0.22 ENST00000509979.1
ENST00000513100.1
ENST00000508161.1
ENST00000455559.2
NREP
neuronal regeneration related protein
chr5_-_88179302 0.22 ENST00000504921.2
MEF2C
myocyte enhancer factor 2C
chr12_-_50616382 0.21 ENST00000552783.1
LIMA1
LIM domain and actin binding 1
chrX_+_10031499 0.21 ENST00000454666.1
WWC3
WWC family member 3
chr4_-_159094194 0.21 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
FAM198B
family with sequence similarity 198, member B
chr10_-_72141330 0.21 ENST00000395011.1
ENST00000395010.1
LRRC20
leucine rich repeat containing 20
chr19_+_41509851 0.20 ENST00000593831.1
ENST00000330446.5
CYP2B6
cytochrome P450, family 2, subfamily B, polypeptide 6
chr12_+_49121213 0.20 ENST00000548380.1
LINC00935
long intergenic non-protein coding RNA 935
chr11_+_73003824 0.20 ENST00000538328.1
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr12_+_96588279 0.20 ENST00000552142.1
ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr3_-_185270342 0.19 ENST00000424591.2
LIPH
lipase, member H
chr12_+_27396901 0.19 ENST00000541191.1
ENST00000389032.3
STK38L
serine/threonine kinase 38 like
chr12_+_26348582 0.19 ENST00000535504.1
SSPN
sarcospan
chrX_+_152760397 0.19 ENST00000331595.4
ENST00000431891.1
BGN
biglycan
chr3_-_158390282 0.19 ENST00000264265.3
LXN
latexin
chr11_+_10477733 0.18 ENST00000528723.1
AMPD3
adenosine monophosphate deaminase 3
chr3_+_69134080 0.18 ENST00000273258.3
ARL6IP5
ADP-ribosylation-like factor 6 interacting protein 5
chr3_+_132316081 0.18 ENST00000249887.2
ACKR4
atypical chemokine receptor 4
chr18_-_77276057 0.18 ENST00000597412.1
AC018445.1
Uncharacterized protein
chr12_-_92536433 0.18 ENST00000551563.2
ENST00000546975.1
ENST00000549802.1
C12orf79
chromosome 12 open reading frame 79
chr15_-_28957469 0.17 ENST00000563027.1
ENST00000340249.3
GOLGA8M
golgin A8 family, member M
chr20_+_42574317 0.17 ENST00000358131.5
TOX2
TOX high mobility group box family member 2
chr13_-_99667960 0.17 ENST00000448493.2
DOCK9
dedicator of cytokinesis 9
chr15_+_100347228 0.17 ENST00000559714.1
ENST00000560059.1
CTD-2054N24.2
Uncharacterized protein
chr2_+_189839046 0.17 ENST00000304636.3
ENST00000317840.5
COL3A1
collagen, type III, alpha 1
chr19_+_16059818 0.17 ENST00000322107.1
OR10H4
olfactory receptor, family 10, subfamily H, member 4
chr4_-_104021009 0.16 ENST00000509245.1
ENST00000296424.4
BDH2
3-hydroxybutyrate dehydrogenase, type 2
chr18_+_3466248 0.16 ENST00000581029.1
ENST00000581442.1
ENST00000579007.1
RP11-838N2.4
RP11-838N2.4
chr8_+_86121448 0.16 ENST00000520225.1
E2F5
E2F transcription factor 5, p130-binding
chr8_+_81397846 0.16 ENST00000379091.4
ZBTB10
zinc finger and BTB domain containing 10
chr15_-_43785274 0.16 ENST00000413546.1
TP53BP1
tumor protein p53 binding protein 1
chr15_-_74374891 0.16 ENST00000290438.3
GOLGA6A
golgin A6 family, member A
chr12_+_50366620 0.16 ENST00000315520.5
AQP6
aquaporin 6, kidney specific
chr18_-_53177984 0.15 ENST00000543082.1
TCF4
transcription factor 4
chr2_+_11817713 0.15 ENST00000449576.2
LPIN1
lipin 1
chr1_+_203734296 0.15 ENST00000442561.2
ENST00000367217.5
LAX1
lymphocyte transmembrane adaptor 1
chr7_+_134551583 0.15 ENST00000435928.1
CALD1
caldesmon 1
chr4_-_178363581 0.15 ENST00000264595.2
AGA
aspartylglucosaminidase
chr6_-_111136513 0.15 ENST00000368911.3
CDK19
cyclin-dependent kinase 19
chr18_-_53257027 0.15 ENST00000568740.1
ENST00000564403.2
ENST00000537578.1
TCF4
transcription factor 4
chr9_-_20622478 0.14 ENST00000355930.6
ENST00000380338.4
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr3_-_65583561 0.14 ENST00000460329.2
MAGI1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr8_-_117043 0.14 ENST00000320901.3
OR4F21
olfactory receptor, family 4, subfamily F, member 21
chr4_+_86748898 0.14 ENST00000509300.1
ARHGAP24
Rho GTPase activating protein 24
chr1_+_367640 0.14 ENST00000426406.1
OR4F29
olfactory receptor, family 4, subfamily F, member 29
chr1_+_204042723 0.14 ENST00000367204.1
SOX13
SRY (sex determining region Y)-box 13
chr18_-_52989217 0.14 ENST00000570287.2
TCF4
transcription factor 4
chr6_+_15246501 0.14 ENST00000341776.2
JARID2
jumonji, AT rich interactive domain 2
chr9_+_22446814 0.14 ENST00000325870.2
DMRTA1
DMRT-like family A1
chr8_-_81787006 0.14 ENST00000327835.3
ZNF704
zinc finger protein 704
chr3_+_196366616 0.14 ENST00000426755.1
PIGX
phosphatidylinositol glycan anchor biosynthesis, class X
chr3_-_149375783 0.14 ENST00000467467.1
ENST00000460517.1
ENST00000360632.3
WWTR1
WW domain containing transcription regulator 1
chr19_+_15052301 0.14 ENST00000248072.3
OR7C2
olfactory receptor, family 7, subfamily C, member 2
chr3_-_111852128 0.13 ENST00000308910.4
GCSAM
germinal center-associated, signaling and motility
chr11_+_11863500 0.13 ENST00000527733.1
ENST00000539466.1
USP47
ubiquitin specific peptidase 47
chr5_+_140207536 0.13 ENST00000529310.1
ENST00000527624.1
PCDHA6
protocadherin alpha 6
chr5_+_38445641 0.13 ENST00000397210.3
ENST00000506135.1
ENST00000508131.1
EGFLAM
EGF-like, fibronectin type III and laminin G domains
chr4_+_154387480 0.13 ENST00000409663.3
ENST00000440693.1
ENST00000409959.3
KIAA0922
KIAA0922
chr5_-_54468974 0.13 ENST00000381375.2
ENST00000296733.1
ENST00000322374.6
ENST00000334206.5
ENST00000331730.3
CDC20B
cell division cycle 20B
chr2_+_28618532 0.13 ENST00000545753.1
FOSL2
FOS-like antigen 2
chr2_-_228244013 0.13 ENST00000304568.3
TM4SF20
transmembrane 4 L six family member 20
chr3_-_182817367 0.13 ENST00000265594.4
MCCC1
methylcrotonoyl-CoA carboxylase 1 (alpha)
chr9_-_4666337 0.13 ENST00000381890.5
SPATA6L
spermatogenesis associated 6-like
chr12_+_54393880 0.13 ENST00000303450.4
HOXC9
homeobox C9
chr18_-_53089723 0.13 ENST00000561992.1
ENST00000562512.2
TCF4
transcription factor 4
chr14_+_75761099 0.12 ENST00000561000.1
ENST00000558575.1
RP11-293M10.5
RP11-293M10.5
chr11_-_68780824 0.12 ENST00000441623.1
ENST00000309099.6
MRGPRF
MAS-related GPR, member F
chr11_+_130542851 0.12 ENST00000317019.2
C11orf44
chromosome 11 open reading frame 44
chr15_-_32695396 0.12 ENST00000512626.2
ENST00000435655.2
GOLGA8K
AC139426.2
golgin A8 family, member K
Uncharacterized protein; cDNA FLJ52611
chr8_+_70404996 0.12 ENST00000402687.4
ENST00000419716.3
SULF1
sulfatase 1
chr14_+_105047478 0.12 ENST00000410013.1
C14orf180
chromosome 14 open reading frame 180
chr13_-_62001982 0.12 ENST00000409186.1
PCDH20
protocadherin 20
chr11_+_92085707 0.12 ENST00000525166.1
FAT3
FAT atypical cadherin 3
chr1_-_226926864 0.12 ENST00000429204.1
ENST00000366784.1
ITPKB
inositol-trisphosphate 3-kinase B
chr1_+_46640750 0.12 ENST00000372003.1
TSPAN1
tetraspanin 1
chr7_+_79998864 0.12 ENST00000435819.1
CD36
CD36 molecule (thrombospondin receptor)
chr8_-_131399110 0.12 ENST00000521426.1
ASAP1
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr2_-_157198860 0.12 ENST00000409572.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr11_+_36616044 0.12 ENST00000334307.5
ENST00000531554.1
ENST00000347206.4
ENST00000534635.1
ENST00000446510.2
ENST00000530697.1
ENST00000527108.1
C11orf74
chromosome 11 open reading frame 74
chr3_+_69134124 0.11 ENST00000478935.1
ARL6IP5
ADP-ribosylation-like factor 6 interacting protein 5
chr6_+_152011628 0.11 ENST00000404742.1
ENST00000440973.1
ESR1
estrogen receptor 1
chr19_-_2427863 0.11 ENST00000215570.3
TIMM13
translocase of inner mitochondrial membrane 13 homolog (yeast)
chr15_+_30375158 0.11 ENST00000341650.6
ENST00000567927.1
GOLGA8J
golgin A8 family, member J
chr10_-_74385811 0.11 ENST00000603011.1
ENST00000401998.3
ENST00000361114.5
ENST00000604238.1
MICU1
mitochondrial calcium uptake 1
chr4_+_26585686 0.11 ENST00000505206.1
ENST00000511789.1
TBC1D19
TBC1 domain family, member 19
chr14_-_30396802 0.11 ENST00000415220.2
PRKD1
protein kinase D1
chr8_-_124553437 0.11 ENST00000517956.1
ENST00000443022.2
FBXO32
F-box protein 32
chr8_-_95274536 0.11 ENST00000297596.2
ENST00000396194.2
GEM
GTP binding protein overexpressed in skeletal muscle
chr9_+_27109392 0.11 ENST00000406359.4
TEK
TEK tyrosine kinase, endothelial
chr6_-_159466042 0.11 ENST00000338313.5
TAGAP
T-cell activation RhoGTPase activating protein
chr21_+_17553910 0.11 ENST00000428669.2
LINC00478
long intergenic non-protein coding RNA 478
chr19_+_35939154 0.11 ENST00000599180.2
FFAR2
free fatty acid receptor 2
chr20_+_43990576 0.11 ENST00000372727.1
ENST00000414310.1
SYS1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr13_+_73629107 0.11 ENST00000539231.1
KLF5
Kruppel-like factor 5 (intestinal)
chr1_-_154164534 0.11 ENST00000271850.7
ENST00000368530.2
TPM3
tropomyosin 3
chr8_+_38831683 0.11 ENST00000302495.4
HTRA4
HtrA serine peptidase 4
chr6_-_43595039 0.11 ENST00000307114.7
GTPBP2
GTP binding protein 2
chr10_-_65028817 0.11 ENST00000542921.1
JMJD1C
jumonji domain containing 1C
chr6_-_119670919 0.11 ENST00000368468.3
MAN1A1
mannosidase, alpha, class 1A, member 1
chr4_+_159131346 0.11 ENST00000508243.1
ENST00000296529.6
TMEM144
transmembrane protein 144
chr1_+_92632542 0.10 ENST00000409154.4
ENST00000370378.4
KIAA1107
KIAA1107
chr12_+_11802753 0.10 ENST00000396373.4
ETV6
ets variant 6
chr17_-_39780819 0.10 ENST00000311208.8
KRT17
keratin 17
chr15_+_84841242 0.10 ENST00000558195.1
RP11-182J1.16
ubiquitin-conjugating enzyme E2Q family member 2-like
chr16_-_21436459 0.10 ENST00000448012.2
ENST00000504841.2
ENST00000419180.2
NPIPB3
nuclear pore complex interacting protein family, member B3
chr8_+_81397876 0.10 ENST00000430430.1
ZBTB10
zinc finger and BTB domain containing 10
chr7_+_136553824 0.10 ENST00000320658.5
ENST00000453373.1
ENST00000397608.3
ENST00000402486.3
ENST00000401861.1
CHRM2
cholinergic receptor, muscarinic 2
chr10_-_65028938 0.10 ENST00000402544.1
JMJD1C
jumonji domain containing 1C
chr6_-_11232891 0.10 ENST00000379433.5
ENST00000379446.5
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr12_-_91573316 0.09 ENST00000393155.1
DCN
decorin
chr1_-_203320617 0.09 ENST00000354955.4
FMOD
fibromodulin
chr10_-_1246317 0.09 ENST00000381305.1
ADARB2
adenosine deaminase, RNA-specific, B2 (non-functional)
chr12_-_123921256 0.09 ENST00000280571.8
RILPL2
Rab interacting lysosomal protein-like 2
chr11_-_14358620 0.09 ENST00000531421.1
RRAS2
related RAS viral (r-ras) oncogene homolog 2
chr1_+_162602244 0.09 ENST00000367922.3
ENST00000367921.3
DDR2
discoidin domain receptor tyrosine kinase 2
chr1_+_179712298 0.09 ENST00000341785.4
FAM163A
family with sequence similarity 163, member A
chr1_+_151682909 0.09 ENST00000326413.3
ENST00000442233.2
RIIAD1
AL589765.1
regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1
Uncharacterized protein; cDNA FLJ36032 fis, clone TESTI2017069
chr5_+_179125368 0.09 ENST00000502296.1
ENST00000504734.1
ENST00000415618.2
CANX
calnexin
chr7_+_1126461 0.09 ENST00000297469.3
GPER1
G protein-coupled estrogen receptor 1
chr11_+_118754475 0.09 ENST00000292174.4
CXCR5
chemokine (C-X-C motif) receptor 5
chr2_+_1417228 0.09 ENST00000382269.3
ENST00000337415.3
ENST00000345913.4
ENST00000346956.3
ENST00000349624.3
ENST00000539820.1
ENST00000329066.4
ENST00000382201.3
TPO
thyroid peroxidase
chr7_+_1126437 0.09 ENST00000413368.1
ENST00000397092.1
GPER1
G protein-coupled estrogen receptor 1
chr11_+_11863579 0.09 ENST00000399455.2
USP47
ubiquitin specific peptidase 47
chr11_-_110167352 0.09 ENST00000533991.1
ENST00000528498.1
ENST00000405097.1
ENST00000528900.1
ENST00000530301.1
ENST00000343115.4
RDX
radixin
chr11_+_60970852 0.08 ENST00000325558.6
PGA3
pepsinogen 3, group I (pepsinogen A)
chr1_-_94703118 0.08 ENST00000260526.6
ENST00000370217.3
ARHGAP29
Rho GTPase activating protein 29
chr2_-_97535708 0.08 ENST00000305476.5
SEMA4C
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr16_+_15528332 0.08 ENST00000566490.1
C16orf45
chromosome 16 open reading frame 45
chr1_+_150254936 0.08 ENST00000447007.1
ENST00000369095.1
ENST00000369094.1
C1orf51
chromosome 1 open reading frame 51
chr14_-_107013465 0.08 ENST00000390625.2
IGHV3-49
immunoglobulin heavy variable 3-49
chr1_-_77685084 0.08 ENST00000370812.3
ENST00000359130.1
ENST00000445065.1
ENST00000370813.5
PIGK
phosphatidylinositol glycan anchor biosynthesis, class K
chr5_-_158757895 0.08 ENST00000231228.2
IL12B
interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
chr9_-_124922021 0.08 ENST00000537618.1
ENST00000373768.3
NDUFA8
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa
chrX_-_39186610 0.08 ENST00000429281.1
ENST00000448597.1
RP11-265P11.2
RP11-265P11.2
chr15_+_41099788 0.08 ENST00000299173.10
ENST00000566407.1
ZFYVE19
zinc finger, FYVE domain containing 19
chr13_-_76056250 0.08 ENST00000377636.3
ENST00000431480.2
ENST00000377625.2
ENST00000425511.1
TBC1D4
TBC1 domain family, member 4
chr3_+_157261116 0.08 ENST00000468043.1
ENST00000459838.1
ENST00000461040.1
ENST00000449199.2
ENST00000426338.2
C3orf55
chromosome 3 open reading frame 55
chr16_-_29415350 0.08 ENST00000524087.1
NPIPB11
nuclear pore complex interacting protein family, member B11
chrX_-_119763835 0.08 ENST00000371313.2
ENST00000304661.5
C1GALT1C1
C1GALT1-specific chaperone 1
chr1_+_175036966 0.08 ENST00000239462.4
TNN
tenascin N
chr1_+_86046433 0.08 ENST00000451137.2
CYR61
cysteine-rich, angiogenic inducer, 61
chr12_+_109915179 0.08 ENST00000434735.2
UBE3B
ubiquitin protein ligase E3B
chr1_-_244006528 0.08 ENST00000336199.5
ENST00000263826.5
AKT3
v-akt murine thymoma viral oncogene homolog 3
chr15_+_23255242 0.08 ENST00000450802.3
GOLGA8I
golgin A8 family, member I
chr14_+_81421861 0.08 ENST00000298171.2
TSHR
thyroid stimulating hormone receptor
chr8_-_70016408 0.07 ENST00000518540.1
RP11-600K15.1
RP11-600K15.1
chr1_+_168545711 0.07 ENST00000367818.3
XCL1
chemokine (C motif) ligand 1
chr8_-_141774467 0.07 ENST00000520151.1
ENST00000519024.1
ENST00000519465.1
PTK2
protein tyrosine kinase 2
chr1_-_156051789 0.07 ENST00000532414.2
MEX3A
mex-3 RNA binding family member A
chr15_+_58702742 0.07 ENST00000356113.6
ENST00000414170.3
LIPC
lipase, hepatic
chr5_-_94417339 0.07 ENST00000429576.2
ENST00000508509.1
ENST00000510732.1
MCTP1
multiple C2 domains, transmembrane 1
chr18_-_52989525 0.07 ENST00000457482.3
TCF4
transcription factor 4
chr15_-_59981479 0.07 ENST00000607373.1
BNIP2
BCL2/adenovirus E1B 19kDa interacting protein 2
chr15_-_43785303 0.07 ENST00000382039.3
ENST00000450115.2
ENST00000382044.4
TP53BP1
tumor protein p53 binding protein 1
chr15_-_30685752 0.07 ENST00000299847.2
ENST00000397827.3
CHRFAM7A
CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion
chr4_+_86749045 0.07 ENST00000514229.1
ARHGAP24
Rho GTPase activating protein 24
chrX_+_154254960 0.07 ENST00000369498.3
FUNDC2
FUN14 domain containing 2
chr13_-_67804445 0.07 ENST00000456367.1
ENST00000377861.3
ENST00000544246.1
PCDH9
protocadherin 9
chr12_-_59314246 0.07 ENST00000320743.3
LRIG3
leucine-rich repeats and immunoglobulin-like domains 3
chr9_-_73483958 0.07 ENST00000377101.1
ENST00000377106.1
ENST00000360823.2
ENST00000377105.1
TRPM3
transient receptor potential cation channel, subfamily M, member 3
chr11_-_113577014 0.07 ENST00000544634.1
ENST00000539732.1
ENST00000538770.1
ENST00000536856.1
ENST00000544476.1
TMPRSS5
transmembrane protease, serine 5

Network of associatons between targets according to the STRING database.

First level regulatory network of NFATC1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 1.6 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.3 GO:0048859 formation of anatomical boundary(GO:0048859)
0.1 0.5 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.1 0.2 GO:0030264 nuclear fragmentation involved in apoptotic nuclear change(GO:0030264)
0.1 1.5 GO:0072189 ureter development(GO:0072189)
0.1 0.2 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 0.3 GO:1901910 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.6 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.1 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.0 0.3 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.1 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.0 0.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.2 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.7 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 1.5 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.2 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.1 GO:2000566 positive regulation of thymocyte migration(GO:2000412) positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.0 0.2 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.1 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.1 GO:1903445 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 0.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.1 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.2 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.1 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.3 GO:0051956 negative regulation of mitochondrial membrane potential(GO:0010917) negative regulation of amino acid transport(GO:0051956)
0.0 0.1 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.1 GO:2000330 positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.2 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.1 GO:2000768 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.0 0.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.5 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.2 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.1 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:0060179 male mating behavior(GO:0060179)
0.0 0.1 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.1 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.0 0.1 GO:0055096 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0 0.2 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.0 0.0 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
0.0 0.2 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 1.0 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.0 0.7 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.1 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.1 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.0 0.4 GO:0003416 endochondral bone growth(GO:0003416)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.2 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.0 0.1 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
0.0 0.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.1 GO:0060591 chondroblast differentiation(GO:0060591)
0.0 0.1 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.0 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.0 0.1 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.0 GO:0090291 negative regulation of mesonephros development(GO:0061218) negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191) negative regulation of osteoclast proliferation(GO:0090291) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.0 0.0 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.2 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.1 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 0.0 GO:0034140 negative regulation of toll-like receptor 3 signaling pathway(GO:0034140)
0.0 0.0 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.0 0.1 GO:0072307 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.1 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.1 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.1 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.6 GO:0071953 elastic fiber(GO:0071953)
0.1 0.9 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.2 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.0 0.9 GO:0000145 exocyst(GO:0000145)
0.0 0.3 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.2 GO:0031906 late endosome lumen(GO:0031906)
0.0 0.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.4 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.6 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 0.8 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.1 0.2 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.1 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.2 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 0.2 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.1 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.6 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.3 GO:0052846 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0 0.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.2 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.0 0.2 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.3 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.2 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.1 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)
0.0 0.1 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.2 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.0 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.0 0.0 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.1 GO:0045159 myosin II binding(GO:0045159)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.0 GO:0001596 angiotensin type I receptor activity(GO:0001596)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.1 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.6 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.6 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics