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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for NFATC2_NFATC3

Z-value: 0.97

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Transcription factors associated with NFATC2_NFATC3

Gene Symbol Gene ID Gene Info
ENSG00000101096.15 nuclear factor of activated T cells 2
ENSG00000072736.14 nuclear factor of activated T cells 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFATC2hg19_v2_chr20_-_50159198_501592990.601.5e-03Click!
NFATC3hg19_v2_chr16_+_68119440_68119561-0.321.2e-01Click!

Activity profile of NFATC2_NFATC3 motif

Sorted Z-values of NFATC2_NFATC3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_92413353 3.44 ENST00000556154.1
fibulin 5
chr3_-_141747950 3.16 ENST00000497579.1
transcription factor Dp-2 (E2F dimerization partner 2)
chr7_+_142919130 2.79 ENST00000408947.3
taste receptor, type 2, member 40
chr4_+_41614909 2.06 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIM and calponin homology domains 1
chr1_-_173020056 1.97 ENST00000239468.2
ENST00000404377.3
tumor necrosis factor (ligand) superfamily, member 18
chr12_+_26348582 1.96 ENST00000535504.1
sarcospan
chr3_+_152017924 1.94 ENST00000465907.2
ENST00000492948.1
ENST00000485509.1
ENST00000464596.1
muscleblind-like splicing regulator 1
chr21_-_35899113 1.93 ENST00000492600.1
ENST00000481448.1
ENST00000381132.2
regulator of calcineurin 1
chr18_+_77155856 1.73 ENST00000253506.5
ENST00000591814.1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr14_-_92413727 1.56 ENST00000267620.10
fibulin 5
chr12_-_9268707 1.51 ENST00000318602.7
alpha-2-macroglobulin
chr7_+_44663908 1.51 ENST00000543843.1
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr13_+_97928395 1.41 ENST00000445661.2
muscleblind-like splicing regulator 2
chr8_+_86121448 1.40 ENST00000520225.1
E2F transcription factor 5, p130-binding
chr11_+_128563652 1.24 ENST00000527786.2
Fli-1 proto-oncogene, ETS transcription factor
chr6_+_106546808 1.22 ENST00000369089.3
PR domain containing 1, with ZNF domain
chr14_+_103589789 1.16 ENST00000558056.1
ENST00000560869.1
tumor necrosis factor, alpha-induced protein 2
chr10_-_116444371 1.13 ENST00000533213.2
ENST00000369252.4
actin binding LIM protein 1
chr14_+_32546145 1.09 ENST00000556611.1
ENST00000539826.2
Rho GTPase activating protein 5
chr16_-_66952779 1.07 ENST00000570262.1
ENST00000394055.3
ENST00000299752.4
cadherin 16, KSP-cadherin
chr6_+_106534192 1.05 ENST00000369091.2
ENST00000369096.4
PR domain containing 1, with ZNF domain
chr4_+_156587853 1.03 ENST00000506455.1
ENST00000511108.1
guanylate cyclase 1, soluble, alpha 3
chr6_-_10415218 0.99 ENST00000466073.1
ENST00000498450.1
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr13_-_99667960 0.99 ENST00000448493.2
dedicator of cytokinesis 9
chr6_-_10415470 0.94 ENST00000379604.2
ENST00000379613.3
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr8_+_66955648 0.94 ENST00000522619.1
DnaJ (Hsp40) homolog, subfamily C, member 5 beta
chr16_-_66952742 0.92 ENST00000565235.2
ENST00000568632.1
ENST00000565796.1
cadherin 16, KSP-cadherin
chr18_+_77155942 0.90 ENST00000397790.2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr13_+_97874574 0.89 ENST00000343600.4
ENST00000345429.6
ENST00000376673.3
muscleblind-like splicing regulator 2
chr12_-_323689 0.88 ENST00000428720.1
solute carrier family 6 (neurotransmitter transporter), member 12
chr8_+_70404996 0.86 ENST00000402687.4
ENST00000419716.3
sulfatase 1
chr11_-_76381029 0.79 ENST00000407242.2
ENST00000421973.1
leucine rich repeat containing 32
chr7_-_156685841 0.78 ENST00000354505.4
ENST00000540390.1
limb development membrane protein 1
chr14_+_63671577 0.76 ENST00000555125.1
ras homolog family member J
chr10_+_30722866 0.74 ENST00000263056.1
mitogen-activated protein kinase kinase kinase 8
chr7_-_22259845 0.74 ENST00000420196.1
Rap guanine nucleotide exchange factor (GEF) 5
chr4_-_159080806 0.73 ENST00000590648.1
family with sequence similarity 198, member B
chr3_-_112360116 0.72 ENST00000206423.3
ENST00000439685.2
coiled-coil domain containing 80
chr4_-_16900184 0.69 ENST00000515064.1
LIM domain binding 2
chr5_-_111093759 0.66 ENST00000509979.1
ENST00000513100.1
ENST00000508161.1
ENST00000455559.2
neuronal regeneration related protein
chr1_-_85870177 0.64 ENST00000542148.1
dimethylarginine dimethylaminohydrolase 1
chr2_+_201997492 0.64 ENST00000494258.1
CASP8 and FADD-like apoptosis regulator
chr9_-_73483958 0.62 ENST00000377101.1
ENST00000377106.1
ENST00000360823.2
ENST00000377105.1
transient receptor potential cation channel, subfamily M, member 3
chr1_-_246670519 0.60 ENST00000388985.4
ENST00000490107.1
SET and MYND domain containing 3
chr17_-_36981556 0.60 ENST00000536127.1
ENST00000225428.5
CWC25 spliceosome-associated protein homolog (S. cerevisiae)
chr11_+_101983176 0.60 ENST00000524575.1
Yes-associated protein 1
chr15_-_70994612 0.60 ENST00000558758.1
ENST00000379983.2
ENST00000560441.1
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr2_-_191885686 0.59 ENST00000432058.1
signal transducer and activator of transcription 1, 91kDa
chr12_-_50616122 0.59 ENST00000552823.1
ENST00000552909.1
LIM domain and actin binding 1
chr9_-_13165457 0.59 ENST00000542239.1
ENST00000538841.1
ENST00000433359.2
multiple PDZ domain protein
chr6_+_155537771 0.58 ENST00000275246.7
T-cell lymphoma invasion and metastasis 2
chr1_-_161207875 0.57 ENST00000512372.1
ENST00000437437.2
ENST00000442691.2
ENST00000412844.2
ENST00000428574.2
ENST00000505005.1
ENST00000508740.1
ENST00000508387.1
ENST00000504010.1
ENST00000511676.1
ENST00000502985.1
ENST00000367981.3
ENST00000515621.1
ENST00000511944.1
ENST00000511748.1
ENST00000367984.4
ENST00000367985.3
nuclear receptor subfamily 1, group I, member 3
chr8_-_81787006 0.57 ENST00000327835.3
zinc finger protein 704
chr8_-_80680078 0.56 ENST00000337919.5
ENST00000354724.3
hes-related family bHLH transcription factor with YRPW motif 1
chr11_+_102188224 0.55 ENST00000263464.3
baculoviral IAP repeat containing 3
chr17_+_30814707 0.55 ENST00000584792.1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr8_+_81397876 0.55 ENST00000430430.1
zinc finger and BTB domain containing 10
chr1_-_1149506 0.54 ENST00000379236.3
tumor necrosis factor receptor superfamily, member 4
chr3_-_71353892 0.54 ENST00000484350.1
forkhead box P1
chr12_-_104443890 0.54 ENST00000547583.1
ENST00000360814.4
ENST00000546851.1
glycosyltransferase 8 domain containing 2
chr1_-_161207953 0.53 ENST00000367982.4
nuclear receptor subfamily 1, group I, member 3
chr3_+_127770455 0.53 ENST00000464451.1
Sec61 alpha 1 subunit (S. cerevisiae)
chr1_-_161208013 0.53 ENST00000515452.1
ENST00000367983.4
nuclear receptor subfamily 1, group I, member 3
chr4_-_168155300 0.53 ENST00000541637.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr9_+_115913222 0.52 ENST00000259392.3
solute carrier family 31 (copper transporter), member 2
chrX_+_9431324 0.51 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
transducin (beta)-like 1X-linked
chr3_-_149051194 0.51 ENST00000470080.1
transmembrane 4 L six family member 18
chr3_+_111578131 0.51 ENST00000498699.1
pleckstrin homology-like domain, family B, member 2
chr1_-_161207986 0.51 ENST00000506209.1
ENST00000367980.2
nuclear receptor subfamily 1, group I, member 3
chr15_+_67358163 0.49 ENST00000327367.4
SMAD family member 3
chrX_+_41193407 0.49 ENST00000457138.2
ENST00000441189.2
DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
chr7_+_134551583 0.49 ENST00000435928.1
caldesmon 1
chr13_+_92050928 0.49 ENST00000377067.3
glypican 5
chr8_-_95274536 0.47 ENST00000297596.2
ENST00000396194.2
GTP binding protein overexpressed in skeletal muscle
chr12_-_50616382 0.47 ENST00000552783.1
LIM domain and actin binding 1
chr5_-_16742330 0.47 ENST00000505695.1
ENST00000427430.2
myosin X
chr15_-_90892669 0.46 ENST00000412799.2
GABA(A) receptors associated protein like 3, pseudogene
chrX_+_135730373 0.46 ENST00000370628.2
CD40 ligand
chr5_+_140772381 0.45 ENST00000398604.2
protocadherin gamma subfamily A, 8
chr1_-_68698197 0.45 ENST00000370973.2
ENST00000370971.1
wntless Wnt ligand secretion mediator
chrX_+_135730297 0.44 ENST00000370629.2
CD40 ligand
chr4_-_159094194 0.44 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
family with sequence similarity 198, member B
chr17_+_74372662 0.44 ENST00000591651.1
ENST00000545180.1
sphingosine kinase 1
chr18_+_55888767 0.44 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr11_+_102188272 0.44 ENST00000532808.1
baculoviral IAP repeat containing 3
chr8_+_98900132 0.44 ENST00000520016.1
matrilin 2
chr17_+_74261413 0.44 ENST00000587913.1
UBA-like domain containing 2
chr7_+_28452130 0.44 ENST00000357727.2
cAMP responsive element binding protein 5
chr15_-_37391507 0.43 ENST00000557796.2
ENST00000397620.2
Meis homeobox 2
chr1_-_55352834 0.43 ENST00000371269.3
24-dehydrocholesterol reductase
chr1_+_61547405 0.42 ENST00000371189.4
nuclear factor I/A
chr15_-_50411412 0.42 ENST00000284509.6
ATPase, class I, type 8B, member 4
chr10_-_7453445 0.42 ENST00000379713.3
ENST00000397167.1
ENST00000397160.3
Scm-like with four mbt domains 2
chr8_+_22423219 0.42 ENST00000523965.1
ENST00000521554.1
sorbin and SH3 domain containing 3
chr3_+_152017360 0.42 ENST00000485910.1
ENST00000463374.1
muscleblind-like splicing regulator 1
chr1_+_209602609 0.41 ENST00000458250.1
MIR205 host gene (non-protein coding)
chr19_+_41509851 0.41 ENST00000593831.1
ENST00000330446.5
cytochrome P450, family 2, subfamily B, polypeptide 6
chr18_-_500692 0.41 ENST00000400256.3
collectin sub-family member 12
chr1_-_21606013 0.41 ENST00000357071.4
endothelin converting enzyme 1
chr14_+_63671105 0.41 ENST00000316754.3
ras homolog family member J
chr7_+_1126461 0.41 ENST00000297469.3
G protein-coupled estrogen receptor 1
chr9_-_13175823 0.41 ENST00000545857.1
multiple PDZ domain protein
chr3_-_39195037 0.41 ENST00000273153.5
cysteine-serine-rich nuclear protein 1
chr6_+_106959718 0.41 ENST00000369066.3
absent in melanoma 1
chr15_+_93443419 0.41 ENST00000557381.1
ENST00000420239.2
chromodomain helicase DNA binding protein 2
chr18_-_53070913 0.40 ENST00000568186.1
ENST00000564228.1
transcription factor 4
chr3_+_148447887 0.40 ENST00000475347.1
ENST00000474935.1
ENST00000461609.1
angiotensin II receptor, type 1
chr5_+_38846101 0.40 ENST00000274276.3
oncostatin M receptor
chr1_-_244006528 0.40 ENST00000336199.5
ENST00000263826.5
v-akt murine thymoma viral oncogene homolog 3
chr17_+_16120512 0.40 ENST00000581006.1
ENST00000584797.1
ENST00000498772.2
ENST00000225609.5
ENST00000395844.4
ENST00000477745.1
phosphatidylinositol glycan anchor biosynthesis, class L
chr7_-_150754935 0.40 ENST00000297518.4
cyclin-dependent kinase 5
chr6_+_127439749 0.40 ENST00000356698.4
R-spondin 3
chr1_+_82266053 0.39 ENST00000370715.1
ENST00000370713.1
ENST00000319517.6
ENST00000370717.2
ENST00000394879.1
ENST00000271029.4
ENST00000335786.5
latrophilin 2
chr1_+_46640750 0.38 ENST00000372003.1
tetraspanin 1
chr15_-_50647274 0.38 ENST00000543881.1
GA binding protein transcription factor, beta subunit 1
chr5_-_94620239 0.37 ENST00000515393.1
multiple C2 domains, transmembrane 1
chr1_+_153651078 0.37 ENST00000368680.3
natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)
chrX_-_15683147 0.37 ENST00000380342.3
transmembrane protein 27
chr7_+_1126437 0.37 ENST00000413368.1
ENST00000397092.1
G protein-coupled estrogen receptor 1
chr5_-_115910630 0.37 ENST00000343348.6
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chrX_+_84498989 0.37 ENST00000395402.1
zinc finger protein 711
chr12_+_79258547 0.36 ENST00000457153.2
synaptotagmin I
chr1_-_151319283 0.36 ENST00000392746.3
regulatory factor X, 5 (influences HLA class II expression)
chr22_-_43355858 0.35 ENST00000402229.1
ENST00000407585.1
ENST00000453079.1
protein kinase C and casein kinase substrate in neurons 2
chr18_-_53089723 0.35 ENST00000561992.1
ENST00000562512.2
transcription factor 4
chr8_-_17555164 0.35 ENST00000297488.6
microtubule associated tumor suppressor 1
chr4_-_168155417 0.35 ENST00000511269.1
ENST00000506697.1
ENST00000512042.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr12_+_79258444 0.35 ENST00000261205.4
synaptotagmin I
chr5_+_159895275 0.35 ENST00000517927.1
microRNA 146a
chr2_+_27237615 0.35 ENST00000458529.1
ENST00000402218.1
microtubule-associated protein, RP/EB family, member 3
chr5_+_140762268 0.35 ENST00000518325.1
protocadherin gamma subfamily A, 7
chr4_+_71200681 0.35 ENST00000273936.5
calcium-binding protein, spermatid-specific 1
chr9_+_124062071 0.35 ENST00000373818.4
gelsolin
chr4_-_168155169 0.34 ENST00000534949.1
ENST00000535728.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr5_-_111091948 0.34 ENST00000447165.2
neuronal regeneration related protein
chr13_+_32838801 0.34 ENST00000542859.1
furry homolog (Drosophila)
chr4_+_74718906 0.34 ENST00000226524.3
platelet factor 4 variant 1
chr20_+_33759854 0.34 ENST00000216968.4
protein C receptor, endothelial
chrX_-_63005405 0.34 ENST00000374878.1
ENST00000437457.2
Cdc42 guanine nucleotide exchange factor (GEF) 9
chrX_-_48815633 0.34 ENST00000428668.2
OTU domain containing 5
chr7_-_82073031 0.34 ENST00000356253.5
ENST00000423588.1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr12_-_71031185 0.33 ENST00000548122.1
ENST00000551525.1
ENST00000550358.1
protein tyrosine phosphatase, receptor type, B
chr10_+_128593978 0.33 ENST00000280333.6
dedicator of cytokinesis 1
chr13_+_46039037 0.32 ENST00000349995.5
component of oligomeric golgi complex 3
chr15_-_52587945 0.32 ENST00000443683.2
ENST00000558479.1
ENST00000261839.7
myosin VC
chr10_+_94590910 0.32 ENST00000371547.4
exocyst complex component 6
chr10_+_120967072 0.32 ENST00000392870.2
G protein-coupled receptor kinase 5
chr5_+_140864649 0.32 ENST00000306593.1
protocadherin gamma subfamily C, 4
chr17_-_7120498 0.32 ENST00000485100.1
discs, large homolog 4 (Drosophila)
chr12_+_54393880 0.32 ENST00000303450.4
homeobox C9
chrX_-_117107680 0.32 ENST00000447671.2
ENST00000262820.3
kelch-like family member 13
chr1_+_86046433 0.32 ENST00000451137.2
cysteine-rich, angiogenic inducer, 61
chr1_+_244816237 0.32 ENST00000302550.11
desumoylating isopeptidase 2
chr7_+_117120017 0.32 ENST00000003084.6
ENST00000454343.1
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
chr3_-_27764190 0.32 ENST00000537516.1
eomesodermin
chr10_+_74451883 0.32 ENST00000373053.3
ENST00000357157.6
mitochondrial calcium uniporter
chr17_+_36584662 0.32 ENST00000431231.2
ENST00000437668.3
Rho GTPase activating protein 23
chr18_-_53069419 0.32 ENST00000570177.2
transcription factor 4
chr7_-_122342966 0.32 ENST00000447240.1
ring finger protein 148
chr6_-_32191834 0.32 ENST00000375023.3
notch 4
chr18_-_52989217 0.32 ENST00000570287.2
transcription factor 4
chr7_-_122342988 0.31 ENST00000434824.1
ring finger protein 148
chr15_-_37391614 0.31 ENST00000219869.9
Meis homeobox 2
chr1_-_155959853 0.31 ENST00000462460.2
ENST00000368316.1
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr17_+_39261584 0.31 ENST00000391415.1
keratin associated protein 4-9
chr1_+_84609944 0.31 ENST00000370685.3
protein kinase, cAMP-dependent, catalytic, beta
chrX_-_117107542 0.31 ENST00000371878.1
kelch-like family member 13
chr17_+_7341586 0.30 ENST00000575235.1
fibroblast growth factor 11
chr9_-_16705069 0.30 ENST00000471301.2
basonuclin 2
chr9_+_103204553 0.30 ENST00000502978.1
ENST00000334943.6
MSANTD3-TMEFF1 readthrough
transmembrane protein with EGF-like and two follistatin-like domains 1
chr15_+_63354769 0.30 ENST00000558910.1
tropomyosin 1 (alpha)
chr16_+_55542910 0.30 ENST00000262134.5
lysophosphatidylcholine acyltransferase 2
chr15_-_50647370 0.30 ENST00000558970.1
ENST00000396464.3
ENST00000560825.1
GA binding protein transcription factor, beta subunit 1
chr4_-_186733363 0.30 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
sorbin and SH3 domain containing 2
chr20_+_33464238 0.29 ENST00000360596.2
acyl-CoA synthetase short-chain family member 2
chr1_-_204135450 0.29 ENST00000272190.8
ENST00000367195.2
renin
chr4_-_168155577 0.29 ENST00000541354.1
ENST00000509854.1
ENST00000512681.1
ENST00000421836.2
ENST00000510741.1
ENST00000510403.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr1_-_153517473 0.29 ENST00000368715.1
S100 calcium binding protein A4
chr1_+_36038971 0.29 ENST00000373235.3
transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon)
chr6_-_112575838 0.29 ENST00000455073.1
laminin, alpha 4
chr3_+_130279178 0.28 ENST00000358511.6
ENST00000453409.2
collagen, type VI, alpha 6
chr19_+_51226648 0.28 ENST00000599973.1
C-type lectin domain family 11, member A
chr7_+_108210012 0.28 ENST00000249356.3
DnaJ (Hsp40) homolog, subfamily B, member 9
chr8_-_117043 0.28 ENST00000320901.3
olfactory receptor, family 4, subfamily F, member 21
chr9_+_125376948 0.28 ENST00000297913.2
olfactory receptor, family 1, subfamily Q, member 1
chr4_+_54966198 0.27 ENST00000326902.2
ENST00000503800.1
GS homeobox 2
chr6_-_62996066 0.27 ENST00000281156.4
KH domain containing, RNA binding, signal transduction associated 2
chr22_-_19512893 0.27 ENST00000403084.1
ENST00000413119.2
claudin 5
chr1_+_367640 0.27 ENST00000426406.1
olfactory receptor, family 4, subfamily F, member 29
chr19_+_50380917 0.27 ENST00000535102.2
TBC1 domain family, member 17
chr2_+_234580499 0.27 ENST00000354728.4
UDP glucuronosyltransferase 1 family, polypeptide A9
chr19_-_1095330 0.27 ENST00000586746.1
polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
chr5_+_173316341 0.27 ENST00000520867.1
ENST00000334035.5
cytoplasmic polyadenylation element binding protein 4
chr15_-_82338460 0.27 ENST00000558133.1
ENST00000329713.4
mex-3 RNA binding family member B
chr2_+_191334212 0.26 ENST00000444317.1
ENST00000535751.1
major facilitator superfamily domain containing 6
chr17_+_45331184 0.26 ENST00000559488.1
ENST00000571680.1
ENST00000435993.2
integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
chr8_-_23712312 0.26 ENST00000290271.2
stanniocalcin 1
chr5_-_176923846 0.26 ENST00000506537.1
PDZ and LIM domain 7 (enigma)
chr17_+_7387677 0.26 ENST00000322644.6
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
chr2_+_234580525 0.26 ENST00000609637.1
UDP glucuronosyltransferase 1 family, polypeptide A8

Network of associatons between targets according to the STRING database.

First level regulatory network of NFATC2_NFATC3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:2000329 negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.5 1.9 GO:0003409 optic cup structural organization(GO:0003409)
0.5 2.3 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.4 5.0 GO:0048251 elastic fiber assembly(GO:0048251)
0.3 1.5 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.3 0.8 GO:0030264 nuclear fragmentation involved in apoptotic nuclear change(GO:0030264)
0.2 0.7 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.2 0.9 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.2 0.5 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.2 0.5 GO:0021722 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.2 0.5 GO:0039019 pronephric nephron development(GO:0039019)
0.2 1.0 GO:0052551 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.2 0.5 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.2 0.8 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.6 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.1 0.4 GO:0046521 sphingoid catabolic process(GO:0046521)
0.1 0.6 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.8 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.1 1.0 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.1 0.5 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.1 0.5 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.3 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1 1.5 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.4 GO:0097325 melanocyte proliferation(GO:0097325)
0.1 0.4 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.1 1.4 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 0.5 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.3 GO:0031448 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.1 0.4 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.3 GO:0001172 transcription, RNA-templated(GO:0001172)
0.1 0.4 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.1 1.0 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.1 0.2 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.7 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.1 0.3 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.1 0.3 GO:0019541 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.1 0.4 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.1 0.6 GO:0042256 mature ribosome assembly(GO:0042256)
0.1 1.7 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.3 GO:0044856 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.1 2.8 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 0.3 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.1 3.9 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 0.2 GO:0045210 FasL biosynthetic process(GO:0045210)
0.1 0.4 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 3.2 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.3 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.1 0.7 GO:0051552 flavone metabolic process(GO:0051552)
0.1 0.3 GO:0046086 adenosine biosynthetic process(GO:0046086)
0.1 1.2 GO:0051601 exocyst localization(GO:0051601)
0.1 0.3 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.6 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 0.4 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1 0.2 GO:0038189 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of retinal ganglion cell axon guidance(GO:1902336) regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1 0.3 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 0.6 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.1 0.2 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.1 0.4 GO:0070836 plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.1 0.2 GO:0021569 rhombomere 3 development(GO:0021569)
0.1 0.3 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
0.1 0.8 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 0.6 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.2 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.1 0.4 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.1 0.9 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.7 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.0 0.3 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.3 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.0 0.4 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.2 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.7 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:0044278 cell wall disruption in other organism(GO:0044278)
0.0 0.1 GO:0021764 amygdala development(GO:0021764)
0.0 0.4 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.0 0.9 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.3 GO:0097338 response to clozapine(GO:0097338)
0.0 1.3 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.2 GO:0035989 tendon development(GO:0035989)
0.0 0.2 GO:0048539 bone marrow development(GO:0048539)
0.0 0.2 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.5 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.1 GO:0034239 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241)
0.0 0.1 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.2 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.2 GO:1903786 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 0.2 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.0 0.4 GO:0031340 positive regulation of vesicle fusion(GO:0031340) positive regulation of amino acid transport(GO:0051957)
0.0 0.2 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.5 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.2 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029)
0.0 0.3 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.2 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.0 0.3 GO:2000771 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.9 GO:0072189 ureter development(GO:0072189)
0.0 0.2 GO:0007619 courtship behavior(GO:0007619)
0.0 0.2 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.0 0.3 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.1 GO:0042700 luteinizing hormone signaling pathway(GO:0042700)
0.0 2.5 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 1.2 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 0.3 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.6 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.4 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.3 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.2 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405)
0.0 0.1 GO:0060578 subthalamic nucleus development(GO:0021763) deltoid tuberosity development(GO:0035993) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578) cell proliferation involved in outflow tract morphogenesis(GO:0061325)
0.0 0.1 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.0 0.1 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.0 0.2 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.0 0.1 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.2 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.0 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.3 GO:0002138 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0 0.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.2 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.4 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.0 0.1 GO:0043129 surfactant homeostasis(GO:0043129)
0.0 0.4 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.3 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.2 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.4 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.2 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.3 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.2 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.2 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0 0.4 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.1 GO:1903970 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.0 0.2 GO:0035771 interleukin-4-mediated signaling pathway(GO:0035771)
0.0 0.1 GO:0090042 tubulin deacetylation(GO:0090042)
0.0 0.4 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.0 GO:2000330 positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.0 0.7 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.1 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0 0.1 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0 0.1 GO:0016598 protein arginylation(GO:0016598)
0.0 0.4 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.3 GO:0060579 ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581)
0.0 0.1 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.0 0.1 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.0 0.0 GO:0007412 axon target recognition(GO:0007412)
0.0 0.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.2 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 2.8 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.1 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.1 GO:0014732 skeletal muscle atrophy(GO:0014732) striated muscle atrophy(GO:0014891)
0.0 0.2 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.0 0.0 GO:0015793 glycerol transport(GO:0015793)
0.0 0.1 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.0 0.5 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 1.2 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.3 GO:0051024 positive regulation of immunoglobulin secretion(GO:0051024)
0.0 0.5 GO:0010669 epithelial structure maintenance(GO:0010669)
0.0 0.1 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.1 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.1 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.0 1.7 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 0.2 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.1 GO:0010269 response to selenium ion(GO:0010269)
0.0 0.1 GO:1904044 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650) response to aldosterone(GO:1904044)
0.0 0.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.4 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.2 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.1 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.1 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.1 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.4 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.0 GO:0072161 mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 0.4 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.3 GO:0043586 tongue development(GO:0043586)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 1.0 GO:0008542 visual learning(GO:0008542)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 0.1 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.0 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.0 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.0 0.2 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.3 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.0 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.0 0.1 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.2 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.1 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.7 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.2 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.2 GO:0045116 protein neddylation(GO:0045116)
0.0 0.9 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.2 GO:0001556 oocyte maturation(GO:0001556)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:0060157 urea transport(GO:0015840) urinary bladder development(GO:0060157)
0.0 0.0 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.2 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.0 GO:0071953 elastic fiber(GO:0071953)
0.2 0.9 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 0.6 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 0.4 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.1 0.7 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 1.5 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 0.4 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.1 0.5 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 0.3 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 0.3 GO:1990246 uniplex complex(GO:1990246)
0.1 0.4 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 0.1 GO:0043159 acrosomal matrix(GO:0043159)
0.1 0.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 1.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 0.8 GO:0030478 actin cap(GO:0030478)
0.1 1.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 1.8 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.8 GO:0045180 basal cortex(GO:0045180)
0.0 1.7 GO:0000145 exocyst(GO:0000145)
0.0 0.6 GO:0044327 dendritic spine head(GO:0044327)
0.0 1.0 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.2 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 0.2 GO:1905202 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.0 0.2 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 0.4 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.3 GO:0070695 FHF complex(GO:0070695)
0.0 0.2 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 0.3 GO:0031415 NatA complex(GO:0031415)
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 2.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:1902560 GMP reductase complex(GO:1902560)
0.0 0.2 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.2 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.6 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 0.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.1 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.2 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.5 GO:0032433 filopodium tip(GO:0032433)
0.0 0.1 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.0 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 3.5 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.4 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.2 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.1 GO:0030430 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 0.1 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.6 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0000346 transcription export complex(GO:0000346)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.2 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.5 GO:0005605 basal lamina(GO:0005605)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.3 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.5 GO:0051233 spindle midzone(GO:0051233)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.3 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.3 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.6 GO:0001069 regulatory region RNA binding(GO:0001069)
0.5 1.5 GO:0019959 interleukin-8 binding(GO:0019959)
0.4 1.5 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.4 2.1 GO:0004882 androgen receptor activity(GO:0004882)
0.3 1.9 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.3 0.9 GO:0005174 CD40 receptor binding(GO:0005174)
0.3 2.6 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.3 0.8 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.2 0.5 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.2 0.5 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.2 0.5 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 0.9 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.9 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 1.8 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.6 GO:0035939 microsatellite binding(GO:0035939)
0.1 2.8 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 0.7 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.3 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 0.3 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1 0.5 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.6 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.3 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.1 0.4 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.1 0.5 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 1.0 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.4 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.7 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 0.6 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1 1.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.7 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.2 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.1 0.4 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.2 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.1 0.3 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.4 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.3 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1 0.5 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 0.4 GO:0005534 galactose binding(GO:0005534)
0.1 0.2 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.0 0.6 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.2 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.3 GO:0097001 ceramide binding(GO:0097001)
0.0 0.5 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.2 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.0 3.4 GO:0032813 tumor necrosis factor receptor superfamily binding(GO:0032813)
0.0 1.0 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 1.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.0 0.2 GO:0042019 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 0.0 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.4 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.4 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.3 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.2 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.2 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.2 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.4 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.2 GO:0043813 phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.0 0.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.8 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.0 0.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.4 GO:0045159 myosin II binding(GO:0045159)
0.0 5.1 GO:0005178 integrin binding(GO:0005178)
0.0 0.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.4 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.3 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.0 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.1 GO:0004057 arginyltransferase activity(GO:0004057)
0.0 0.1 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.4 GO:0017166 vinculin binding(GO:0017166)
0.0 0.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.1 GO:0046870 cadmium ion binding(GO:0046870)
0.0 0.1 GO:0000035 acyl binding(GO:0000035)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.4 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.9 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.0 1.8 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.5 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.7 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.1 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.9 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.5 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 2.1 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.7 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.2 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.1 GO:0031432 titin binding(GO:0031432)
0.0 0.3 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.4 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.1 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.5 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.4 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.9 GO:0043022 ribosome binding(GO:0043022)
0.0 0.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 0.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.1 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.1 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.0 0.3 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.1 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.0 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.0 0.5 GO:0042605 peptide antigen binding(GO:0042605)
0.0 1.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.0 GO:0070546 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.1 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.0 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.6 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 1.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.0 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.1 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.2 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.1 GO:0008179 adenylate cyclase binding(GO:0008179)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.6 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.7 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.0 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.9 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 4.3 PID E2F PATHWAY E2F transcription factor network
0.0 1.6 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.4 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 2.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.7 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 1.0 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.0 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.5 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 1.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 5.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.7 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 1.3 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.5 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.5 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.6 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 2.1 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.8 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.2 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.5 PID INSULIN PATHWAY Insulin Pathway
0.0 0.2 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.2 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.6 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.2 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 1.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 1.9 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 1.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 1.6 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 1.0 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.4 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 1.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.2 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.9 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.6 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.8 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 1.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.2 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.3 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.4 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 1.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.5 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 1.1 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.2 REACTOME CD28 CO STIMULATION Genes involved in CD28 co-stimulation
0.0 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.5 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.2 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.9 REACTOME IL 3 5 AND GM CSF SIGNALING Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.0 1.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.6 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.2 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.2 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC