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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for NFE2L1

Z-value: 0.84

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Transcription factors associated with NFE2L1

Gene Symbol Gene ID Gene Info
NFE2L1
ENSG00000082641.11 nuclear factor, erythroid 2 like 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFE2L1hg19_v2_chr17_+_46125707_461257460.563.4e-03Click!

Activity profile of NFE2L1 motif

Sorted Z-values of NFE2L1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_169703203 1.83 ENST00000333360.7
ENST00000367781.4
ENST00000367782.4
ENST00000367780.4
ENST00000367779.4
SELE
selectin E
chr4_+_74606223 1.75 ENST00000307407.3
ENST00000401931.1
IL8
interleukin 8
chr9_-_123676827 1.17 ENST00000546084.1
TRAF1
TNF receptor-associated factor 1
chr10_-_49860525 1.16 ENST00000435790.2
ARHGAP22
Rho GTPase activating protein 22
chr15_+_89182156 1.13 ENST00000379224.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr15_+_89182178 1.12 ENST00000559876.1
ISG20
interferon stimulated exonuclease gene 20kDa
chr15_+_89181974 0.96 ENST00000306072.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr11_+_60197069 0.94 ENST00000528905.1
ENST00000528093.1
MS4A5
membrane-spanning 4-domains, subfamily A, member 5
chr3_-_127541194 0.93 ENST00000453507.2
MGLL
monoglyceride lipase
chr16_+_31044413 0.89 ENST00000394998.1
STX4
syntaxin 4
chr2_+_102721023 0.79 ENST00000409589.1
ENST00000409329.1
IL1R1
interleukin 1 receptor, type I
chr17_-_39306054 0.76 ENST00000343246.4
KRTAP4-5
keratin associated protein 4-5
chr1_+_159409512 0.75 ENST00000423932.3
OR10J1
olfactory receptor, family 10, subfamily J, member 1
chr15_+_28624878 0.75 ENST00000450328.2
GOLGA8F
golgin A8 family, member F
chr22_-_30968813 0.70 ENST00000443111.2
ENST00000443136.1
ENST00000426220.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chr2_+_201994042 0.70 ENST00000417748.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr6_+_132891461 0.67 ENST00000275198.1
TAAR6
trace amine associated receptor 6
chr6_-_154751629 0.66 ENST00000424998.1
CNKSR3
CNKSR family member 3
chr2_+_201994208 0.65 ENST00000440180.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr9_-_128246769 0.62 ENST00000444226.1
MAPKAP1
mitogen-activated protein kinase associated protein 1
chr22_+_30805086 0.61 ENST00000439838.1
ENST00000439023.3
RP4-539M6.19
Uncharacterized protein
chr14_+_22538811 0.61 ENST00000390450.3
TRAV22
T cell receptor alpha variable 22
chr16_+_31044812 0.60 ENST00000313843.3
STX4
syntaxin 4
chr2_+_169923577 0.57 ENST00000432060.2
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr10_-_24770632 0.56 ENST00000596413.1
AL353583.1
AL353583.1
chr14_+_102276192 0.55 ENST00000557714.1
PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr14_+_24779376 0.54 ENST00000530080.1
LTB4R2
leukotriene B4 receptor 2
chr4_-_123542224 0.52 ENST00000264497.3
IL21
interleukin 21
chr17_+_39394250 0.51 ENST00000254072.6
KRTAP9-8
keratin associated protein 9-8
chr15_+_71228826 0.51 ENST00000558456.1
ENST00000560158.2
ENST00000558808.1
ENST00000559806.1
ENST00000559069.1
LRRC49
leucine rich repeat containing 49
chr9_-_140082983 0.50 ENST00000323927.2
ANAPC2
anaphase promoting complex subunit 2
chr2_-_105030466 0.49 ENST00000449772.1
AC068535.3
AC068535.3
chr11_+_63137251 0.48 ENST00000310969.4
ENST00000279178.3
SLC22A9
solute carrier family 22 (organic anion transporter), member 9
chr17_+_7461613 0.48 ENST00000438470.1
ENST00000436057.1
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr2_+_169926047 0.46 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr6_+_29274403 0.45 ENST00000377160.2
OR14J1
olfactory receptor, family 14, subfamily J, member 1
chr17_+_26662730 0.43 ENST00000226225.2
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr1_-_231004220 0.43 ENST00000366663.5
C1orf198
chromosome 1 open reading frame 198
chr17_+_26662597 0.42 ENST00000544907.2
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr19_+_41949054 0.42 ENST00000378187.2
C19orf69
chromosome 19 open reading frame 69
chr14_+_67291158 0.42 ENST00000555456.1
GPHN
gephyrin
chr1_+_29241027 0.42 ENST00000373797.1
EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr2_+_169923504 0.40 ENST00000357546.2
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr12_-_39734783 0.39 ENST00000552961.1
KIF21A
kinesin family member 21A
chr11_+_60163775 0.39 ENST00000300187.6
ENST00000395005.2
MS4A14
membrane-spanning 4-domains, subfamily A, member 14
chr18_+_55888767 0.38 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr6_-_3157760 0.38 ENST00000333628.3
TUBB2A
tubulin, beta 2A class IIa
chr19_-_42721819 0.38 ENST00000336034.4
ENST00000598200.1
ENST00000598727.1
ENST00000596251.1
DEDD2
death effector domain containing 2
chr9_-_130477912 0.38 ENST00000543175.1
PTRH1
peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae)
chr8_+_67039278 0.38 ENST00000276573.7
ENST00000350034.4
TRIM55
tripartite motif containing 55
chr2_-_136594740 0.38 ENST00000264162.2
LCT
lactase
chr7_-_142232071 0.38 ENST00000390364.3
TRBV10-1
T cell receptor beta variable 10-1(gene/pseudogene)
chr15_-_62937380 0.38 ENST00000560347.1
ENST00000558940.1
RP11-625H11.1
Uncharacterized protein
chr19_-_51530916 0.37 ENST00000594768.1
KLK11
kallikrein-related peptidase 11
chr12_-_10151773 0.37 ENST00000298527.6
ENST00000348658.4
CLEC1B
C-type lectin domain family 1, member B
chr1_-_183387723 0.37 ENST00000287713.6
NMNAT2
nicotinamide nucleotide adenylyltransferase 2
chr6_-_43027105 0.37 ENST00000230413.5
ENST00000487429.1
ENST00000489623.1
ENST00000468957.1
MRPL2
mitochondrial ribosomal protein L2
chr12_-_81763184 0.37 ENST00000548670.1
ENST00000541570.2
ENST00000553058.1
PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr4_+_54927213 0.36 ENST00000595906.1
AC110792.1
HCG2027126; Uncharacterized protein
chr14_+_22615942 0.36 ENST00000390457.2
TRAV27
T cell receptor alpha variable 27
chr6_+_30539153 0.35 ENST00000326195.8
ENST00000376545.3
ENST00000396515.4
ENST00000441867.1
ENST00000468958.1
ABCF1
ATP-binding cassette, sub-family F (GCN20), member 1
chr9_-_117853297 0.35 ENST00000542877.1
ENST00000537320.1
ENST00000341037.4
TNC
tenascin C
chr19_-_44160768 0.35 ENST00000593447.1
PLAUR
plasminogen activator, urokinase receptor
chr20_+_60174827 0.35 ENST00000543233.1
CDH4
cadherin 4, type 1, R-cadherin (retinal)
chr16_-_46797149 0.34 ENST00000536476.1
MYLK3
myosin light chain kinase 3
chr3_-_112218378 0.34 ENST00000334529.5
BTLA
B and T lymphocyte associated
chr20_-_44516256 0.34 ENST00000372519.3
SPATA25
spermatogenesis associated 25
chr12_+_121570631 0.34 ENST00000546057.1
ENST00000377162.2
ENST00000328963.5
ENST00000535250.1
ENST00000541446.1
P2RX7
purinergic receptor P2X, ligand-gated ion channel, 7
chr1_-_31661000 0.34 ENST00000263693.1
ENST00000398657.2
ENST00000526106.1
NKAIN1
Na+/K+ transporting ATPase interacting 1
chr9_+_92219919 0.34 ENST00000252506.6
ENST00000375769.1
GADD45G
growth arrest and DNA-damage-inducible, gamma
chr17_-_39324424 0.34 ENST00000391356.2
KRTAP4-3
keratin associated protein 4-3
chr12_-_91573132 0.33 ENST00000550563.1
ENST00000546370.1
DCN
decorin
chr12_+_112563303 0.33 ENST00000412615.2
TRAFD1
TRAF-type zinc finger domain containing 1
chr12_-_81763127 0.33 ENST00000541017.1
PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr6_+_155537771 0.32 ENST00000275246.7
TIAM2
T-cell lymphoma invasion and metastasis 2
chr6_-_116447283 0.32 ENST00000452729.1
ENST00000243222.4
COL10A1
collagen, type X, alpha 1
chr12_+_112563335 0.32 ENST00000549358.1
ENST00000257604.5
ENST00000548092.1
ENST00000552896.1
TRAFD1
TRAF-type zinc finger domain containing 1
chr2_-_89513402 0.32 ENST00000498435.1
IGKV1-27
immunoglobulin kappa variable 1-27
chr14_+_22236722 0.32 ENST00000390428.3
TRAV6
T cell receptor alpha variable 6
chr7_+_116593953 0.31 ENST00000397750.3
ST7-OT4
ST7 overlapping transcript 4
chr16_+_57662419 0.31 ENST00000388812.4
ENST00000538815.1
ENST00000456916.1
ENST00000567154.1
ENST00000388813.5
ENST00000562558.1
ENST00000566271.2
GPR56
G protein-coupled receptor 56
chr2_-_89545079 0.31 ENST00000468494.1
IGKV2-30
immunoglobulin kappa variable 2-30
chr2_+_114163945 0.31 ENST00000453673.3
IGKV1OR2-108
immunoglobulin kappa variable 1/OR2-108 (non-functional)
chr7_-_139477500 0.31 ENST00000406875.3
ENST00000428878.2
HIPK2
homeodomain interacting protein kinase 2
chr11_+_60197040 0.31 ENST00000300190.2
MS4A5
membrane-spanning 4-domains, subfamily A, member 5
chr22_-_36013368 0.30 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
MB
myoglobin
chr5_+_140864649 0.30 ENST00000306593.1
PCDHGC4
protocadherin gamma subfamily C, 4
chr17_+_56232494 0.30 ENST00000268912.5
OR4D1
olfactory receptor, family 4, subfamily D, member 1
chr3_-_11762202 0.30 ENST00000445411.1
ENST00000404339.1
ENST00000273038.3
VGLL4
vestigial like 4 (Drosophila)
chr1_+_159175201 0.30 ENST00000368121.2
DARC
Duffy blood group, atypical chemokine receptor
chr20_+_59654146 0.30 ENST00000441660.1
RP5-827L5.1
RP5-827L5.1
chr5_+_131993856 0.30 ENST00000304506.3
IL13
interleukin 13
chr15_+_45406519 0.29 ENST00000323030.5
DUOXA2
dual oxidase maturation factor 2
chr12_+_22778291 0.29 ENST00000545979.1
ETNK1
ethanolamine kinase 1
chr16_+_57662138 0.29 ENST00000562414.1
ENST00000561969.1
ENST00000562631.1
ENST00000563445.1
ENST00000565338.1
ENST00000567702.1
GPR56
G protein-coupled receptor 56
chrX_+_47078069 0.29 ENST00000357227.4
ENST00000519758.1
ENST00000520893.1
ENST00000517426.1
CDK16
cyclin-dependent kinase 16
chr19_-_42192096 0.29 ENST00000602225.1
CEACAM7
carcinoembryonic antigen-related cell adhesion molecule 7
chr8_-_101348408 0.28 ENST00000519527.1
ENST00000522369.1
RNF19A
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr15_+_54901540 0.28 ENST00000539562.2
UNC13C
unc-13 homolog C (C. elegans)
chr18_+_32455201 0.28 ENST00000590831.2
DTNA
dystrobrevin, alpha
chr11_-_126138808 0.28 ENST00000332118.6
ENST00000532259.1
SRPR
signal recognition particle receptor (docking protein)
chr11_-_85397167 0.28 ENST00000316398.3
CCDC89
coiled-coil domain containing 89
chr6_-_29395509 0.28 ENST00000377147.2
OR11A1
olfactory receptor, family 11, subfamily A, member 1
chr11_+_65337901 0.27 ENST00000309328.3
ENST00000531405.1
ENST00000527920.1
ENST00000526877.1
ENST00000533115.1
ENST00000526433.1
SSSCA1
Sjogren syndrome/scleroderma autoantigen 1
chrX_-_48814278 0.27 ENST00000455452.1
OTUD5
OTU domain containing 5
chr22_+_32439019 0.27 ENST00000266088.4
SLC5A1
solute carrier family 5 (sodium/glucose cotransporter), member 1
chr22_+_20861858 0.27 ENST00000414658.1
ENST00000432052.1
ENST00000425759.2
ENST00000292733.7
ENST00000542773.1
ENST00000263205.7
ENST00000406969.1
ENST00000382974.2
MED15
mediator complex subunit 15
chr6_-_46293378 0.27 ENST00000330430.6
RCAN2
regulator of calcineurin 2
chr8_+_7738726 0.27 ENST00000314357.3
DEFB103A
defensin, beta 103A
chr18_-_10787140 0.27 ENST00000383408.2
PIEZO2
piezo-type mechanosensitive ion channel component 2
chr1_+_35220613 0.27 ENST00000338513.1
GJB5
gap junction protein, beta 5, 31.1kDa
chr15_+_68582544 0.27 ENST00000566008.1
FEM1B
fem-1 homolog b (C. elegans)
chr8_-_7287870 0.26 ENST00000318124.3
DEFB103B
defensin, beta 103B
chr4_+_4861385 0.26 ENST00000382723.4
MSX1
msh homeobox 1
chrX_+_150345054 0.25 ENST00000218316.3
GPR50
G protein-coupled receptor 50
chr9_-_100684845 0.25 ENST00000375119.3
C9orf156
chromosome 9 open reading frame 156
chr15_-_81616446 0.25 ENST00000302824.6
STARD5
StAR-related lipid transfer (START) domain containing 5
chr4_+_169013666 0.25 ENST00000359299.3
ANXA10
annexin A10
chr11_+_101983176 0.25 ENST00000524575.1
YAP1
Yes-associated protein 1
chr14_+_22356029 0.25 ENST00000390437.2
TRAV12-2
T cell receptor alpha variable 12-2
chr20_-_1638408 0.25 ENST00000303415.3
ENST00000381583.2
SIRPG
signal-regulatory protein gamma
chr11_-_62599505 0.24 ENST00000377897.4
ENST00000394690.1
ENST00000541317.1
ENST00000294179.3
STX5
syntaxin 5
chr6_+_132873832 0.24 ENST00000275200.1
TAAR8
trace amine associated receptor 8
chr11_-_111637083 0.24 ENST00000427203.2
ENST00000341980.6
ENST00000311129.5
ENST00000393055.2
ENST00000426998.2
ENST00000527614.1
PPP2R1B
protein phosphatase 2, regulatory subunit A, beta
chr8_+_22853345 0.24 ENST00000522948.1
RHOBTB2
Rho-related BTB domain containing 2
chrX_-_13835147 0.24 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chr8_-_93029520 0.24 ENST00000521553.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr12_-_52887034 0.24 ENST00000330722.6
KRT6A
keratin 6A
chr19_-_44100275 0.24 ENST00000422989.1
ENST00000598324.1
IRGQ
immunity-related GTPase family, Q
chr1_+_153232160 0.24 ENST00000368742.3
LOR
loricrin
chr19_+_8455077 0.24 ENST00000328024.6
RAB11B
RAB11B, member RAS oncogene family
chr17_+_73663402 0.24 ENST00000355423.3
SAP30BP
SAP30 binding protein
chr9_+_72002837 0.23 ENST00000377216.3
FAM189A2
family with sequence similarity 189, member A2
chrX_-_48814810 0.23 ENST00000376488.3
ENST00000396743.3
ENST00000156084.4
OTUD5
OTU domain containing 5
chr11_-_119991589 0.23 ENST00000526881.1
TRIM29
tripartite motif containing 29
chr7_+_80275752 0.23 ENST00000419819.2
CD36
CD36 molecule (thrombospondin receptor)
chr6_-_33037019 0.23 ENST00000437811.1
HLA-DPA1
major histocompatibility complex, class II, DP alpha 1
chr2_+_159651821 0.23 ENST00000309950.3
ENST00000409042.1
DAPL1
death associated protein-like 1
chr6_-_43595039 0.23 ENST00000307114.7
GTPBP2
GTP binding protein 2
chr5_-_159797627 0.23 ENST00000393975.3
C1QTNF2
C1q and tumor necrosis factor related protein 2
chr12_-_18890940 0.23 ENST00000543242.1
ENST00000539072.1
ENST00000541966.1
ENST00000266505.7
ENST00000447925.2
ENST00000435379.1
PLCZ1
phospholipase C, zeta 1
chr4_+_144303093 0.23 ENST00000505913.1
GAB1
GRB2-associated binding protein 1
chr2_+_27651519 0.22 ENST00000379863.3
NRBP1
nuclear receptor binding protein 1
chr3_-_87325728 0.22 ENST00000350375.2
POU1F1
POU class 1 homeobox 1
chr15_+_81589254 0.22 ENST00000394652.2
IL16
interleukin 16
chr5_+_175223313 0.22 ENST00000359546.4
CPLX2
complexin 2
chr4_-_7436671 0.22 ENST00000319098.4
PSAPL1
prosaposin-like 1 (gene/pseudogene)
chr22_-_32651326 0.21 ENST00000266086.4
SLC5A4
solute carrier family 5 (glucose activated ion channel), member 4
chr1_-_204135450 0.21 ENST00000272190.8
ENST00000367195.2
REN
renin
chr19_+_9361606 0.21 ENST00000456448.1
OR7E24
olfactory receptor, family 7, subfamily E, member 24
chr4_-_119759795 0.21 ENST00000419654.2
SEC24D
SEC24 family member D
chr15_-_43559055 0.21 ENST00000220420.5
ENST00000349114.4
TGM5
transglutaminase 5
chr2_-_89459813 0.21 ENST00000390256.2
IGKV6-21
immunoglobulin kappa variable 6-21 (non-functional)
chr12_-_113574028 0.20 ENST00000546530.1
ENST00000261729.5
RASAL1
RAS protein activator like 1 (GAP1 like)
chr2_-_179567206 0.20 ENST00000414766.1
TTN
titin
chr7_+_141463897 0.20 ENST00000247879.2
TAS2R3
taste receptor, type 2, member 3
chr2_+_162480845 0.20 ENST00000375514.5
ENST00000415876.2
SLC4A10
solute carrier family 4, sodium bicarbonate transporter, member 10
chr19_+_15052301 0.20 ENST00000248072.3
OR7C2
olfactory receptor, family 7, subfamily C, member 2
chr14_+_22977587 0.20 ENST00000390504.1
TRAJ33
T cell receptor alpha joining 33
chr20_+_30555805 0.20 ENST00000562532.2
XKR7
XK, Kell blood group complex subunit-related family, member 7
chr17_+_76210267 0.20 ENST00000301633.4
ENST00000350051.3
ENST00000374948.2
ENST00000590449.1
BIRC5
baculoviral IAP repeat containing 5
chr6_-_170151603 0.20 ENST00000366774.3
TCTE3
t-complex-associated-testis-expressed 3
chr4_-_103998439 0.20 ENST00000503230.1
ENST00000503818.1
SLC9B2
solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
chr10_+_80027105 0.20 ENST00000461034.1
ENST00000476909.1
ENST00000459633.1
LINC00595
long intergenic non-protein coding RNA 595
chr17_+_73663470 0.20 ENST00000583536.1
SAP30BP
SAP30 binding protein
chr15_-_43877062 0.19 ENST00000381885.1
ENST00000396923.3
PPIP5K1
diphosphoinositol pentakisphosphate kinase 1
chr2_-_158345462 0.19 ENST00000439355.1
ENST00000540637.1
CYTIP
cytohesin 1 interacting protein
chr6_+_160183492 0.19 ENST00000541436.1
ACAT2
acetyl-CoA acetyltransferase 2
chr17_-_53800217 0.19 ENST00000424486.2
TMEM100
transmembrane protein 100
chr19_-_1132207 0.19 ENST00000438103.2
SBNO2
strawberry notch homolog 2 (Drosophila)
chr2_-_224467093 0.19 ENST00000305409.2
SCG2
secretogranin II
chrX_+_47077632 0.19 ENST00000457458.2
CDK16
cyclin-dependent kinase 16
chr12_-_11002063 0.19 ENST00000544994.1
ENST00000228811.4
ENST00000540107.1
PRR4
proline rich 4 (lacrimal)
chr5_+_147582387 0.19 ENST00000325630.2
SPINK6
serine peptidase inhibitor, Kazal type 6
chr6_-_22297730 0.19 ENST00000306482.1
PRL
prolactin
chr2_+_162480918 0.19 ENST00000272716.5
ENST00000446997.1
SLC4A10
solute carrier family 4, sodium bicarbonate transporter, member 10
chr22_-_43040515 0.19 ENST00000361740.4
CYB5R3
cytochrome b5 reductase 3
chr6_+_72922505 0.19 ENST00000401910.3
RIMS1
regulating synaptic membrane exocytosis 1
chr11_-_76381029 0.19 ENST00000407242.2
ENST00000421973.1
LRRC32
leucine rich repeat containing 32
chr1_-_113258090 0.19 ENST00000309276.6
PPM1J
protein phosphatase, Mg2+/Mn2+ dependent, 1J
chr2_+_234160340 0.19 ENST00000417017.1
ENST00000392020.4
ENST00000392018.1
ATG16L1
autophagy related 16-like 1 (S. cerevisiae)
chr6_+_72922590 0.19 ENST00000523963.1
RIMS1
regulating synaptic membrane exocytosis 1
chr11_+_117063295 0.18 ENST00000525478.1
ENST00000532062.1
SIDT2
SID1 transmembrane family, member 2
chr19_+_10765003 0.18 ENST00000407004.3
ENST00000589998.1
ENST00000589600.1
ILF3
interleukin enhancer binding factor 3, 90kDa
chr19_-_55686399 0.18 ENST00000587067.1
SYT5
synaptotagmin V
chr8_-_18744528 0.18 ENST00000523619.1
PSD3
pleckstrin and Sec7 domain containing 3
chr6_+_160327974 0.18 ENST00000252660.4
MAS1
MAS1 oncogene
chr11_-_128894053 0.18 ENST00000392657.3
ARHGAP32
Rho GTPase activating protein 32
chr2_-_29297127 0.18 ENST00000331664.5
C2orf71
chromosome 2 open reading frame 71
chr9_-_16727978 0.18 ENST00000418777.1
ENST00000468187.2
BNC2
basonuclin 2
chr2_+_234160217 0.18 ENST00000392017.4
ENST00000347464.5
ENST00000444735.1
ENST00000373525.5
ENST00000419681.1
ATG16L1
autophagy related 16-like 1 (S. cerevisiae)
chr2_-_228244013 0.18 ENST00000304568.3
TM4SF20
transmembrane 4 L six family member 20
chr20_+_57594309 0.18 ENST00000217133.1
TUBB1
tubulin, beta 1 class VI
chrX_-_77582980 0.18 ENST00000373304.3
CYSLTR1
cysteinyl leukotriene receptor 1
chr1_-_155211017 0.18 ENST00000536770.1
ENST00000368373.3
GBA
glucosidase, beta, acid
chr6_-_46048116 0.18 ENST00000185206.6
CLIC5
chloride intracellular channel 5
chr6_+_54173227 0.18 ENST00000259782.4
ENST00000370864.3
TINAG
tubulointerstitial nephritis antigen
chr10_-_115904361 0.18 ENST00000428953.1
ENST00000543782.1
C10orf118
chromosome 10 open reading frame 118
chr6_+_27114861 0.18 ENST00000377459.1
HIST1H2AH
histone cluster 1, H2ah
chr8_+_24151553 0.18 ENST00000265769.4
ENST00000540823.1
ENST00000397649.3
ADAM28
ADAM metallopeptidase domain 28

Network of associatons between targets according to the STRING database.

First level regulatory network of NFE2L1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.2 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.5 1.5 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.3 0.8 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.1 0.4 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.1 1.3 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 0.9 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 1.4 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 0.3 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.1 0.3 GO:1904170 NAD transport(GO:0043132) regulation of bleb assembly(GO:1904170) positive regulation of bleb assembly(GO:1904172)
0.1 0.3 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.1 0.7 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.1 0.4 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.1 0.6 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 0.3 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.1 0.3 GO:0090427 activation of meiosis(GO:0090427)
0.1 0.4 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.2 GO:0035604 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604)
0.1 0.7 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 0.2 GO:0007343 egg activation(GO:0007343)
0.1 1.8 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 0.3 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.1 0.3 GO:1901804 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.1 0.3 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.3 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 0.4 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.1 0.4 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.1 0.2 GO:0051710 cytolysis by symbiont of host cells(GO:0001897) regulation of cytolysis in other organism(GO:0051710)
0.1 0.2 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.1 0.4 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 0.3 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.1 0.2 GO:0048769 sarcomerogenesis(GO:0048769)
0.1 0.6 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 0.3 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.1 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.0 0.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.3 GO:0072564 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0 0.3 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.5 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.5 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.6 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.1 GO:0002582 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588) detection of peptidoglycan(GO:0032499)
0.0 0.2 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.0 0.1 GO:1900158 positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.0 0.3 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.0 0.1 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.0 0.3 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.1 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.0 0.3 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.0 0.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.2 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.0 0.4 GO:0021860 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.6 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.1 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.0 0.1 GO:0060127 subthalamus development(GO:0021539) subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.0 0.1 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.0 0.2 GO:0071105 response to interleukin-11(GO:0071105)
0.0 0.3 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.4 GO:1904417 regulation of xenophagy(GO:1904415) positive regulation of xenophagy(GO:1904417)
0.0 0.2 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0 0.2 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.2 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.0 0.2 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.1 GO:0006203 dGTP catabolic process(GO:0006203)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.1 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.0 0.1 GO:0018874 benzoate metabolic process(GO:0018874)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.2 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.1 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 0.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.2 GO:0045054 constitutive secretory pathway(GO:0045054)
0.0 0.4 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.1 GO:1904073 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.0 0.1 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.3 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0 0.2 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.0 0.1 GO:0071025 RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 0.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.4 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.0 0.1 GO:0006533 aspartate catabolic process(GO:0006533)
0.0 0.1 GO:0045007 depurination(GO:0045007)
0.0 0.5 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.1 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.1 GO:1903248 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204) negative regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901205) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) regulation of cellular amino acid biosynthetic process(GO:2000282) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.0 0.4 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 0.1 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.1 GO:1904772 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.2 GO:0060742 epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.0 1.2 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.1 GO:0014901 regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.0 0.3 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 0.2 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.5 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.3 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 1.4 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0 0.0 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.0 1.4 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.3 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 0.1 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.0 0.7 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.2 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.0 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.2 GO:0046321 positive regulation of fatty acid oxidation(GO:0046321)
0.0 0.1 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.0 GO:0071400 cellular response to oleic acid(GO:0071400)
0.0 0.7 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 0.2 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.4 GO:0030220 platelet formation(GO:0030220)
0.0 0.1 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.3 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.2 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.0 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.0 0.1 GO:0061518 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.1 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.2 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.2 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.2 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.1 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.3 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.1 GO:0048850 hypophysis morphogenesis(GO:0048850)
0.0 0.3 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.1 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.1 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.6 GO:0000322 storage vacuole(GO:0000322)
0.1 0.4 GO:0097441 basilar dendrite(GO:0097441)
0.1 0.2 GO:1902636 kinociliary basal body(GO:1902636)
0.1 1.3 GO:0097342 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.1 0.2 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 0.5 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1 0.3 GO:0044305 calyx of Held(GO:0044305)
0.1 0.2 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.0 0.2 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.3 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.6 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 3.2 GO:0015030 Cajal body(GO:0015030)
0.0 0.2 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.3 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.3 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.2 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.7 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.3 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.0 GO:0030128 clathrin coat of endocytic vesicle(GO:0030128)
0.0 2.0 GO:0045095 keratin filament(GO:0045095)
0.0 0.3 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.1 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.8 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.3 GO:0032059 bleb(GO:0032059)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.0 GO:0001534 radial spoke(GO:0001534)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.0 GO:0043159 acrosomal matrix(GO:0043159)
0.0 0.0 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 1.8 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.1 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.2 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0031045 dense core granule(GO:0031045)
0.0 0.0 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.0 1.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0008859 exoribonuclease II activity(GO:0008859)
0.4 1.5 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.2 0.8 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.2 0.9 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 0.4 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.1 1.4 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1 0.5 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.1 1.8 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.3 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.1 0.2 GO:0004974 leukotriene receptor activity(GO:0004974)
0.1 0.3 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 0.5 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 0.7 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 0.4 GO:0008422 beta-glucosidase activity(GO:0008422)
0.1 1.2 GO:0031996 thioesterase binding(GO:0031996)
0.1 0.3 GO:0004348 glucosylceramidase activity(GO:0004348)
0.1 0.5 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.2 GO:0005148 prolactin receptor binding(GO:0005148)
0.1 0.4 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.1 0.5 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 0.3 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.9 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.3 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.2 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.0 0.1 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 0.2 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.2 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.1 GO:0045518 interleukin-22 receptor binding(GO:0045518)
0.0 0.2 GO:0002046 opsin binding(GO:0002046)
0.0 1.6 GO:0005123 death receptor binding(GO:0005123)
0.0 0.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.5 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.1 GO:0070361 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.0 0.3 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.0 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.4 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.1 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.1 GO:0047783 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.0 0.2 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.1 GO:0032408 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.0 0.2 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.1 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.0 0.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.3 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.7 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.3 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.3 GO:0046790 virion binding(GO:0046790)
0.0 0.3 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.5 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.2 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.6 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.2 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.1 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.0 0.1 GO:0019862 IgA binding(GO:0019862)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.1 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.3 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.0 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.0 0.3 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0080130 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.1 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.0 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.3 GO:0032052 bile acid binding(GO:0032052)
0.0 0.0 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 1.4 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 1.1 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.0 GO:0061769 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.0 0.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.0 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734) polynucleotide phosphatase activity(GO:0098518)
0.0 0.1 GO:0031433 telethonin binding(GO:0031433)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 1.2 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.7 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 1.8 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.1 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.0 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.2 PID FGF PATHWAY FGF signaling pathway
0.0 0.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.3 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.7 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 1.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.7 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 3.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.4 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.4 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.7 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.6 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.9 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.5 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.8 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.9 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.5 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.4 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.2 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 0.5 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.6 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.1 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.4 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.7 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.1 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 1.0 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.1 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1