Project

Inflammatory response time course, HUVEC (Wada et al., 2009)

Navigation
Downloads

Results for NHLH1

Z-value: 0.82

Motif logo

logo of

Transcription factors associated with NHLH1

Gene Symbol Gene ID Gene Info
NHLH1
ENSG00000171786.5 nescient helix-loop-helix 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NHLH1hg19_v2_chr1_+_160336851_160336868-0.038.8e-01Click!

Activity profile of NHLH1 motif

Sorted Z-values of NHLH1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_39382900 4.03 ENST00000377721.3
ENST00000455970.2
KRTAP9-2
keratin associated protein 9-2
chr4_-_186696425 1.64 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
SORBS2
sorbin and SH3 domain containing 2
chr4_-_186697044 1.51 ENST00000437304.2
SORBS2
sorbin and SH3 domain containing 2
chr14_+_63671577 1.17 ENST00000555125.1
RHOJ
ras homolog family member J
chr13_-_72440901 0.98 ENST00000359684.2
DACH1
dachshund homolog 1 (Drosophila)
chr5_+_56111361 0.96 ENST00000399503.3
MAP3K1
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
chr11_-_10830463 0.92 ENST00000527419.1
ENST00000530211.1
ENST00000530702.1
ENST00000524932.1
ENST00000532570.1
EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
chr20_+_34042962 0.86 ENST00000446710.1
ENST00000420564.1
CEP250
centrosomal protein 250kDa
chr11_-_1643368 0.84 ENST00000399682.1
KRTAP5-4
keratin associated protein 5-4
chr14_+_63671105 0.76 ENST00000316754.3
RHOJ
ras homolog family member J
chr18_+_77623668 0.76 ENST00000316249.3
KCNG2
potassium voltage-gated channel, subfamily G, member 2
chr12_-_118406777 0.73 ENST00000339824.5
KSR2
kinase suppressor of ras 2
chr6_+_35995552 0.72 ENST00000468133.1
MAPK14
mitogen-activated protein kinase 14
chr7_+_150065879 0.70 ENST00000397281.2
ENST00000444957.1
ENST00000466559.1
ENST00000489432.2
ENST00000475514.1
ENST00000482680.1
ENST00000488943.1
ENST00000518514.1
ENST00000478789.1
REPIN1
ZNF775
replication initiator 1
zinc finger protein 775
chr8_+_98788057 0.67 ENST00000517924.1
LAPTM4B
lysosomal protein transmembrane 4 beta
chr19_+_14184370 0.66 ENST00000590772.1
hsa-mir-1199
hsa-mir-1199
chr2_+_191513789 0.65 ENST00000409581.1
NAB1
NGFI-A binding protein 1 (EGR1 binding protein 1)
chr14_-_54423529 0.65 ENST00000245451.4
ENST00000559087.1
BMP4
bone morphogenetic protein 4
chr10_-_101945771 0.65 ENST00000370408.2
ENST00000407654.3
ERLIN1
ER lipid raft associated 1
chr22_-_37882395 0.65 ENST00000416983.3
ENST00000424765.2
ENST00000356998.3
MFNG
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr20_-_39317868 0.63 ENST00000373313.2
MAFB
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
chr9_-_139581875 0.59 ENST00000371696.2
AGPAT2
1-acylglycerol-3-phosphate O-acyltransferase 2
chr3_-_32022733 0.59 ENST00000438237.2
ENST00000396556.2
OSBPL10
oxysterol binding protein-like 10
chr1_-_47184745 0.59 ENST00000544071.1
EFCAB14
EF-hand calcium binding domain 14
chr1_-_209979465 0.58 ENST00000542854.1
IRF6
interferon regulatory factor 6
chr9_-_139581848 0.58 ENST00000538402.1
ENST00000371694.3
AGPAT2
1-acylglycerol-3-phosphate O-acyltransferase 2
chr1_+_78511586 0.58 ENST00000370759.3
GIPC2
GIPC PDZ domain containing family, member 2
chr1_-_182360918 0.56 ENST00000339526.4
GLUL
glutamate-ammonia ligase
chr17_-_54991369 0.56 ENST00000537230.1
TRIM25
tripartite motif containing 25
chrX_-_118827113 0.55 ENST00000394617.2
SEPT6
septin 6
chr15_-_69113218 0.54 ENST00000560303.1
ENST00000465139.2
ANP32A
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr11_-_10829851 0.54 ENST00000532082.1
EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
chr1_-_92351769 0.54 ENST00000212355.4
TGFBR3
transforming growth factor, beta receptor III
chr6_+_35995488 0.54 ENST00000229795.3
MAPK14
mitogen-activated protein kinase 14
chr1_-_209979375 0.53 ENST00000367021.3
IRF6
interferon regulatory factor 6
chr13_+_31480328 0.53 ENST00000380482.4
MEDAG
mesenteric estrogen-dependent adipogenesis
chr4_+_86748898 0.52 ENST00000509300.1
ARHGAP24
Rho GTPase activating protein 24
chrX_-_118826784 0.52 ENST00000394616.4
SEPT6
septin 6
chr16_+_69373471 0.51 ENST00000569637.2
NIP7
NIP7, nucleolar pre-rRNA processing protein
chrX_+_84499081 0.51 ENST00000276123.3
ZNF711
zinc finger protein 711
chr4_-_80994619 0.50 ENST00000404191.1
ANTXR2
anthrax toxin receptor 2
chr1_-_21606013 0.50 ENST00000357071.4
ECE1
endothelin converting enzyme 1
chr22_-_21905120 0.50 ENST00000331505.5
RIMBP3C
RIMS binding protein 3C
chr8_-_101963482 0.49 ENST00000419477.2
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr12_+_57482665 0.49 ENST00000300131.3
NAB2
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr12_-_120554534 0.49 ENST00000538903.1
ENST00000534951.1
RAB35
RAB35, member RAS oncogene family
chr4_+_86749045 0.49 ENST00000514229.1
ARHGAP24
Rho GTPase activating protein 24
chr8_+_98788003 0.48 ENST00000521545.2
LAPTM4B
lysosomal protein transmembrane 4 beta
chr6_-_75915757 0.48 ENST00000322507.8
COL12A1
collagen, type XII, alpha 1
chr6_+_35995531 0.47 ENST00000229794.4
MAPK14
mitogen-activated protein kinase 14
chr19_+_16186903 0.47 ENST00000588507.1
TPM4
tropomyosin 4
chr1_-_182360498 0.46 ENST00000417584.2
GLUL
glutamate-ammonia ligase
chrX_-_134049233 0.46 ENST00000370779.4
MOSPD1
motile sperm domain containing 1
chr1_-_47184723 0.46 ENST00000371933.3
EFCAB14
EF-hand calcium binding domain 14
chr20_+_37434329 0.45 ENST00000299824.1
ENST00000373331.2
PPP1R16B
protein phosphatase 1, regulatory subunit 16B
chr7_-_100808843 0.45 ENST00000249330.2
VGF
VGF nerve growth factor inducible
chr8_+_97506033 0.45 ENST00000518385.1
SDC2
syndecan 2
chr17_+_71161140 0.44 ENST00000357585.2
SSTR2
somatostatin receptor 2
chr12_+_57482877 0.44 ENST00000342556.6
ENST00000357680.4
NAB2
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr19_+_47104553 0.43 ENST00000598871.1
ENST00000594523.1
CALM3
calmodulin 3 (phosphorylase kinase, delta)
chr1_+_164528866 0.42 ENST00000420696.2
PBX1
pre-B-cell leukemia homeobox 1
chr9_+_134165063 0.41 ENST00000372264.3
PPAPDC3
phosphatidic acid phosphatase type 2 domain containing 3
chr15_-_75198954 0.41 ENST00000565772.1
FAM219B
family with sequence similarity 219, member B
chr15_-_48937884 0.41 ENST00000560355.1
FBN1
fibrillin 1
chr7_-_11871815 0.40 ENST00000423059.4
THSD7A
thrombospondin, type I, domain containing 7A
chr1_-_182361327 0.39 ENST00000331872.6
ENST00000311223.5
GLUL
glutamate-ammonia ligase
chr8_+_142138711 0.39 ENST00000518347.1
ENST00000262585.2
ENST00000424248.1
ENST00000519811.1
ENST00000520986.1
ENST00000523058.1
DENND3
DENN/MADD domain containing 3
chr20_+_58179582 0.39 ENST00000371015.1
ENST00000395639.4
PHACTR3
phosphatase and actin regulator 3
chr16_-_30107491 0.39 ENST00000566134.1
ENST00000565110.1
ENST00000398841.1
ENST00000398838.4
YPEL3
yippee-like 3 (Drosophila)
chr4_+_87856191 0.39 ENST00000503477.1
AFF1
AF4/FMR2 family, member 1
chr8_+_142138799 0.38 ENST00000518668.1
DENND3
DENN/MADD domain containing 3
chr7_-_105925367 0.38 ENST00000354289.4
NAMPT
nicotinamide phosphoribosyltransferase
chr15_-_34629922 0.37 ENST00000559484.1
ENST00000354181.3
ENST00000558589.1
ENST00000458406.2
SLC12A6
solute carrier family 12 (potassium/chloride transporter), member 6
chr19_-_19051103 0.37 ENST00000542541.2
ENST00000433218.2
HOMER3
homer homolog 3 (Drosophila)
chr19_+_41107249 0.37 ENST00000396819.3
LTBP4
latent transforming growth factor beta binding protein 4
chr10_-_103347883 0.37 ENST00000339310.3
ENST00000370158.3
ENST00000299206.4
ENST00000456836.2
ENST00000413344.1
ENST00000429502.1
ENST00000430045.1
ENST00000370172.1
ENST00000436284.2
ENST00000370162.3
POLL
polymerase (DNA directed), lambda
chr9_+_115513003 0.37 ENST00000374232.3
SNX30
sorting nexin family member 30
chr16_-_90085824 0.37 ENST00000002501.6
DBNDD1
dysbindin (dystrobrevin binding protein 1) domain containing 1
chr15_-_75199213 0.37 ENST00000562698.1
FAM219B
family with sequence similarity 219, member B
chr2_+_70485220 0.37 ENST00000433351.2
ENST00000264441.5
PCYOX1
prenylcysteine oxidase 1
chr1_-_85930823 0.36 ENST00000284031.8
ENST00000539042.1
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr11_+_71249071 0.36 ENST00000398534.3
KRTAP5-8
keratin associated protein 5-8
chr17_-_34122596 0.36 ENST00000250144.8
MMP28
matrix metallopeptidase 28
chr2_-_219696519 0.36 ENST00000545803.1
ENST00000430489.1
ENST00000392098.3
PRKAG3
protein kinase, AMP-activated, gamma 3 non-catalytic subunit
chr5_-_133747589 0.35 ENST00000458198.2
CDKN2AIPNL
CDKN2A interacting protein N-terminal like
chr1_+_32538492 0.35 ENST00000336294.5
TMEM39B
transmembrane protein 39B
chr5_-_54281407 0.34 ENST00000381403.4
ESM1
endothelial cell-specific molecule 1
chr19_+_45281118 0.34 ENST00000270279.3
ENST00000341505.4
CBLC
Cbl proto-oncogene C, E3 ubiquitin protein ligase
chr17_-_39324424 0.34 ENST00000391356.2
KRTAP4-3
keratin associated protein 4-3
chr17_+_28705921 0.34 ENST00000225719.4
CPD
carboxypeptidase D
chr17_+_74261413 0.34 ENST00000587913.1
UBALD2
UBA-like domain containing 2
chr21_+_38071430 0.34 ENST00000290399.6
SIM2
single-minded family bHLH transcription factor 2
chr5_+_176873446 0.34 ENST00000507881.1
PRR7
proline rich 7 (synaptic)
chr9_+_131218336 0.34 ENST00000372814.3
ODF2
outer dense fiber of sperm tails 2
chr4_-_102268484 0.33 ENST00000394853.4
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr1_+_32538520 0.33 ENST00000438825.1
ENST00000456834.2
ENST00000373634.4
ENST00000427288.1
TMEM39B
transmembrane protein 39B
chrX_+_118370211 0.33 ENST00000217971.7
PGRMC1
progesterone receptor membrane component 1
chr12_+_130646999 0.32 ENST00000539839.1
ENST00000229030.4
FZD10
frizzled family receptor 10
chr17_-_27278445 0.32 ENST00000268756.3
ENST00000584685.1
PHF12
PHD finger protein 12
chr3_+_5020801 0.32 ENST00000256495.3
BHLHE40
basic helix-loop-helix family, member e40
chr13_+_49550015 0.32 ENST00000492622.2
FNDC3A
fibronectin type III domain containing 3A
chr18_+_3448455 0.32 ENST00000549780.1
TGIF1
TGFB-induced factor homeobox 1
chr4_+_87856129 0.32 ENST00000395146.4
ENST00000507468.1
AFF1
AF4/FMR2 family, member 1
chr12_-_59313270 0.32 ENST00000379141.4
LRIG3
leucine-rich repeats and immunoglobulin-like domains 3
chr14_-_82000140 0.32 ENST00000555824.1
ENST00000557372.1
ENST00000336735.4
SEL1L
sel-1 suppressor of lin-12-like (C. elegans)
chr19_+_16187085 0.31 ENST00000300933.4
TPM4
tropomyosin 4
chr20_-_48770174 0.30 ENST00000341698.2
TMEM189-UBE2V1
TMEM189-UBE2V1 readthrough
chr19_-_41196458 0.30 ENST00000598779.1
NUMBL
numb homolog (Drosophila)-like
chr2_+_65283506 0.30 ENST00000377990.2
CEP68
centrosomal protein 68kDa
chr8_+_42995548 0.30 ENST00000458501.2
ENST00000379644.4
HGSNAT
heparan-alpha-glucosaminide N-acetyltransferase
chr2_-_232791038 0.30 ENST00000295440.2
ENST00000409852.1
NPPC
natriuretic peptide C
chr4_-_102268628 0.30 ENST00000323055.6
ENST00000512215.1
ENST00000394854.3
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr1_+_3388181 0.29 ENST00000418137.1
ENST00000413250.2
ARHGEF16
Rho guanine nucleotide exchange factor (GEF) 16
chr17_+_39261584 0.29 ENST00000391415.1
KRTAP4-9
keratin associated protein 4-9
chr10_-_89623194 0.29 ENST00000445946.3
KLLN
killin, p53-regulated DNA replication inhibitor
chr10_-_27529486 0.29 ENST00000375888.1
ACBD5
acyl-CoA binding domain containing 5
chr2_+_65283529 0.29 ENST00000546106.1
ENST00000537589.1
ENST00000260569.4
CEP68
centrosomal protein 68kDa
chr2_+_33359646 0.28 ENST00000390003.4
ENST00000418533.2
LTBP1
latent transforming growth factor beta binding protein 1
chr3_-_196911002 0.28 ENST00000452595.1
DLG1
discs, large homolog 1 (Drosophila)
chr2_+_33359687 0.28 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
LTBP1
latent transforming growth factor beta binding protein 1
chr17_-_39191107 0.28 ENST00000344363.5
KRTAP1-3
keratin associated protein 1-3
chr20_-_35274548 0.28 ENST00000262866.4
SLA2
Src-like-adaptor 2
chr8_-_59572093 0.28 ENST00000427130.2
NSMAF
neutral sphingomyelinase (N-SMase) activation associated factor
chr10_+_112257596 0.27 ENST00000369583.3
DUSP5
dual specificity phosphatase 5
chr10_+_1102303 0.27 ENST00000381329.1
WDR37
WD repeat domain 37
chr1_-_244013384 0.27 ENST00000366539.1
AKT3
v-akt murine thymoma viral oncogene homolog 3
chr5_+_139027877 0.27 ENST00000302517.3
CXXC5
CXXC finger protein 5
chr4_-_80994471 0.27 ENST00000295465.4
ANTXR2
anthrax toxin receptor 2
chr7_-_100808394 0.27 ENST00000445482.2
VGF
VGF nerve growth factor inducible
chr3_-_196910721 0.27 ENST00000443183.1
DLG1
discs, large homolog 1 (Drosophila)
chr10_-_81205373 0.27 ENST00000372336.3
ZCCHC24
zinc finger, CCHC domain containing 24
chrX_+_107069063 0.27 ENST00000262843.6
MID2
midline 2
chrX_-_40036520 0.26 ENST00000406200.2
ENST00000378455.4
ENST00000342274.4
BCOR
BCL6 corepressor
chr1_-_91487770 0.26 ENST00000337393.5
ZNF644
zinc finger protein 644
chr2_+_16080659 0.26 ENST00000281043.3
MYCN
v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
chr7_-_767249 0.26 ENST00000403562.1
PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
chr3_-_197024965 0.25 ENST00000392382.2
DLG1
discs, large homolog 1 (Drosophila)
chr15_+_74833518 0.25 ENST00000346246.5
ARID3B
AT rich interactive domain 3B (BRIGHT-like)
chr17_-_18950310 0.25 ENST00000573099.1
GRAP
GRB2-related adaptor protein
chr12_-_31744031 0.25 ENST00000389082.5
DENND5B
DENN/MADD domain containing 5B
chr15_+_25200108 0.25 ENST00000577949.1
ENST00000338094.6
ENST00000338327.4
ENST00000579070.1
ENST00000577565.1
SNURF
SNRPN
SNRPN upstream reading frame protein
small nuclear ribonucleoprotein polypeptide N
chr11_+_62556596 0.25 ENST00000526546.1
TMEM179B
transmembrane protein 179B
chr14_-_37051798 0.24 ENST00000258829.5
NKX2-8
NK2 homeobox 8
chr2_+_232063436 0.24 ENST00000440107.1
ARMC9
armadillo repeat containing 9
chr10_+_82298088 0.24 ENST00000470604.2
SH2D4B
SH2 domain containing 4B
chr19_+_46001697 0.24 ENST00000451287.2
ENST00000324688.4
PPM1N
protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
chr2_+_231577532 0.24 ENST00000258418.5
CAB39
calcium binding protein 39
chr11_-_64825993 0.24 ENST00000340252.4
ENST00000355721.3
ENST00000356632.3
ENST00000355369.2
ENST00000339885.2
ENST00000358658.3
NAALADL1
N-acetylated alpha-linked acidic dipeptidase-like 1
chr8_+_37654424 0.24 ENST00000315215.7
GPR124
G protein-coupled receptor 124
chr1_-_22263790 0.24 ENST00000374695.3
HSPG2
heparan sulfate proteoglycan 2
chr3_-_133614297 0.24 ENST00000486858.1
ENST00000477759.1
RAB6B
RAB6B, member RAS oncogene family
chr2_-_70475701 0.24 ENST00000282574.4
TIA1
TIA1 cytotoxic granule-associated RNA binding protein
chrX_+_9754461 0.23 ENST00000380913.3
SHROOM2
shroom family member 2
chr1_+_117910047 0.23 ENST00000356554.3
MAN1A2
mannosidase, alpha, class 1A, member 2
chr8_+_86376081 0.23 ENST00000285379.5
CA2
carbonic anhydrase II
chr22_-_36902522 0.23 ENST00000397223.4
FOXRED2
FAD-dependent oxidoreductase domain containing 2
chr19_-_46418033 0.23 ENST00000341294.2
NANOS2
nanos homolog 2 (Drosophila)
chr1_-_221915418 0.23 ENST00000323825.3
ENST00000366899.3
DUSP10
dual specificity phosphatase 10
chr9_-_79307096 0.23 ENST00000376717.2
ENST00000223609.6
ENST00000443509.2
PRUNE2
prune homolog 2 (Drosophila)
chr2_+_54683419 0.23 ENST00000356805.4
SPTBN1
spectrin, beta, non-erythrocytic 1
chr3_-_196669298 0.23 ENST00000411704.1
ENST00000452404.2
NCBP2
nuclear cap binding protein subunit 2, 20kDa
chr4_+_95373037 0.23 ENST00000359265.4
ENST00000437932.1
ENST00000380180.3
ENST00000318007.5
ENST00000450793.1
ENST00000538141.1
ENST00000317968.4
ENST00000512274.1
ENST00000503974.1
ENST00000504489.1
ENST00000542407.1
PDLIM5
PDZ and LIM domain 5
chr13_+_35516390 0.23 ENST00000540320.1
ENST00000400445.3
ENST00000310336.4
NBEA
neurobeachin
chr12_+_50017327 0.23 ENST00000261897.1
PRPF40B
PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr7_-_92855762 0.23 ENST00000453812.2
ENST00000394468.2
HEPACAM2
HEPACAM family member 2
chr12_+_50017184 0.23 ENST00000548825.2
PRPF40B
PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr5_+_76114758 0.23 ENST00000514165.1
ENST00000296677.4
F2RL1
coagulation factor II (thrombin) receptor-like 1
chr19_+_1286097 0.22 ENST00000215368.2
EFNA2
ephrin-A2
chr6_-_84418841 0.22 ENST00000369694.2
ENST00000195649.6
SNAP91
synaptosomal-associated protein, 91kDa
chr2_-_19558373 0.22 ENST00000272223.2
OSR1
odd-skipped related transciption factor 1
chr15_-_52472078 0.22 ENST00000396335.4
ENST00000560116.1
ENST00000358784.7
GNB5
guanine nucleotide binding protein (G protein), beta 5
chr6_-_84419101 0.22 ENST00000520302.1
ENST00000520213.1
ENST00000439399.2
ENST00000428679.2
ENST00000437520.1
SNAP91
synaptosomal-associated protein, 91kDa
chr2_+_11052054 0.22 ENST00000295082.1
KCNF1
potassium voltage-gated channel, subfamily F, member 1
chr6_-_84418860 0.22 ENST00000521743.1
SNAP91
synaptosomal-associated protein, 91kDa
chr3_+_42727011 0.22 ENST00000287777.4
KLHL40
kelch-like family member 40
chr8_-_4851937 0.22 ENST00000537824.1
ENST00000542608.1
ENST00000539096.1
CSMD1
CUB and Sushi multiple domains 1
chr11_+_31531291 0.22 ENST00000350638.5
ENST00000379163.5
ENST00000395934.2
ELP4
elongator acetyltransferase complex subunit 4
chr2_+_69002052 0.21 ENST00000497079.1
ARHGAP25
Rho GTPase activating protein 25
chr3_-_65583561 0.21 ENST00000460329.2
MAGI1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr4_-_83719983 0.21 ENST00000319540.4
SCD5
stearoyl-CoA desaturase 5
chr1_+_65210772 0.21 ENST00000371072.4
ENST00000294428.3
RAVER2
ribonucleoprotein, PTB-binding 2
chr6_-_30712313 0.21 ENST00000376377.2
ENST00000259874.5
IER3
immediate early response 3
chr11_-_17035943 0.21 ENST00000355661.3
ENST00000532079.1
ENST00000448080.2
ENST00000531066.1
PLEKHA7
pleckstrin homology domain containing, family A member 7
chr2_-_70475730 0.21 ENST00000445587.1
ENST00000433529.2
ENST00000415783.2
TIA1
TIA1 cytotoxic granule-associated RNA binding protein
chr15_+_25200074 0.21 ENST00000390687.4
ENST00000584968.1
ENST00000346403.6
ENST00000554227.2
SNRPN
small nuclear ribonucleoprotein polypeptide N
chrX_+_118370288 0.21 ENST00000535419.1
PGRMC1
progesterone receptor membrane component 1
chr11_-_67888881 0.21 ENST00000356135.5
CHKA
choline kinase alpha
chr8_-_68255912 0.21 ENST00000262215.3
ENST00000519436.1
ARFGEF1
ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
chrX_+_70521584 0.20 ENST00000373829.3
ENST00000538820.1
ITGB1BP2
integrin beta 1 binding protein (melusin) 2
chr13_-_45150392 0.20 ENST00000501704.2
TSC22D1
TSC22 domain family, member 1
chr7_+_128784712 0.20 ENST00000289407.4
TSPAN33
tetraspanin 33
chr20_-_33680588 0.20 ENST00000451813.2
ENST00000432634.2
TRPC4AP
transient receptor potential cation channel, subfamily C, member 4 associated protein
chr16_-_2770216 0.20 ENST00000302641.3
PRSS27
protease, serine 27
chrX_-_45710920 0.20 ENST00000456532.1
RP5-1158E12.3
RP5-1158E12.3
chr2_-_70475586 0.20 ENST00000416149.2
TIA1
TIA1 cytotoxic granule-associated RNA binding protein
chr21_+_34442439 0.20 ENST00000382348.1
ENST00000333063.5
OLIG1
oligodendrocyte transcription factor 1
chr13_+_88324870 0.20 ENST00000325089.6
SLITRK5
SLIT and NTRK-like family, member 5
chr12_-_113658892 0.20 ENST00000299732.2
ENST00000416617.2
IQCD
IQ motif containing D
chr10_+_105036909 0.20 ENST00000369849.4
INA
internexin neuronal intermediate filament protein, alpha
chr19_+_38755203 0.20 ENST00000587090.1
ENST00000454580.3
SPINT2
serine peptidase inhibitor, Kunitz type, 2

Network of associatons between targets according to the STRING database.

First level regulatory network of NHLH1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.4 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.3 1.7 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.2 0.9 GO:0061227 intermediate mesoderm development(GO:0048389) pattern specification involved in mesonephros development(GO:0061227) anterior/posterior pattern specification involved in kidney development(GO:0072098)
0.2 0.6 GO:0021571 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.2 0.6 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.2 1.0 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.2 0.9 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.2 0.5 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.1 0.5 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.1 1.9 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 0.5 GO:0034959 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.1 1.0 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1 1.0 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.1 0.3 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.1 0.3 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.1 3.4 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 1.0 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 0.7 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 0.4 GO:0046833 snRNA export from nucleus(GO:0006408) positive regulation of RNA export from nucleus(GO:0046833)
0.1 0.4 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1 0.3 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.1 0.2 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1 0.3 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 0.4 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 0.4 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 0.2 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.1 0.4 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 0.3 GO:1900194 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.1 0.4 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.1 0.2 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 0.2 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.1 0.5 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.1 0.4 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.1 0.3 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.1 0.4 GO:0008218 bioluminescence(GO:0008218)
0.1 0.3 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 0.3 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.1 0.4 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.1 0.5 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.1 1.2 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1 0.2 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 0.2 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.1 0.6 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.6 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.2 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.3 GO:0030242 pexophagy(GO:0030242)
0.0 0.2 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.7 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.3 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.2 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.1 GO:0034059 response to anoxia(GO:0034059)
0.0 0.1 GO:0071288 cellular response to mercury ion(GO:0071288)
0.0 0.2 GO:0018032 protein amidation(GO:0018032)
0.0 0.2 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.1 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.0 0.1 GO:0014016 neuroblast differentiation(GO:0014016)
0.0 0.1 GO:0039019 pronephric nephron development(GO:0039019)
0.0 0.2 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.1 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.0 0.9 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 1.1 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.0 0.1 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.5 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.1 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894) positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.0 0.2 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.1 GO:1904397 negative regulation of neuromuscular junction development(GO:1904397)
0.0 0.2 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.2 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 0.5 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.5 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.1 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.1 GO:0044026 DNA hypermethylation(GO:0044026)
0.0 0.1 GO:0006059 hexitol metabolic process(GO:0006059)
0.0 0.3 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.1 GO:2000395 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.0 0.1 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 0.1 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.0 0.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.0 0.4 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.0 0.1 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0 0.3 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.3 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.7 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.3 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.2 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.3 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.1 GO:0006311 meiotic gene conversion(GO:0006311)
0.0 0.1 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 0.1 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.2 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.6 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.1 GO:0071105 response to interleukin-11(GO:0071105)
0.0 0.1 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.1 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.1 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.4 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.1 GO:0060380 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381)
0.0 0.5 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 1.7 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.1 GO:2000334 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0 0.6 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0 0.0 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.3 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.1 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.1 GO:0015798 myo-inositol transport(GO:0015798)
0.0 0.2 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 0.4 GO:0048820 hair follicle maturation(GO:0048820)
0.0 0.8 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.0 0.2 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0 0.2 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:2000568 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.0 0.1 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.2 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.2 GO:0045176 apical protein localization(GO:0045176)
0.0 0.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.4 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.1 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.0 0.4 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.1 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.4 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.5 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.8 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 0.1 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.1 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.1 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.3 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.0 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.0 0.1 GO:1904263 cellular response to leucine(GO:0071233) positive regulation of TORC1 signaling(GO:1904263)
0.0 0.1 GO:0044571 [2Fe-2S] cluster assembly(GO:0044571)
0.0 0.1 GO:1902075 cellular response to salt(GO:1902075)
0.0 0.1 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.1 GO:0015853 adenine transport(GO:0015853)
0.0 0.0 GO:2000619 negative regulation of histone H4-K16 acetylation(GO:2000619)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0005940 septin ring(GO:0005940) septin collar(GO:0032173)
0.1 0.5 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.1 0.5 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.4 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.4 GO:0005846 nuclear cap binding complex(GO:0005846)
0.1 0.6 GO:0097165 nuclear stress granule(GO:0097165)
0.1 1.0 GO:0043219 lateral loop(GO:0043219)
0.1 0.3 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 1.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.6 GO:0005955 calcineurin complex(GO:0005955)
0.1 1.4 GO:0097386 glial cell projection(GO:0097386)
0.1 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.8 GO:0001520 outer dense fiber(GO:0001520)
0.1 0.7 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.3 GO:0019815 B cell receptor complex(GO:0019815)
0.0 1.0 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.7 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.3 GO:0000322 storage vacuole(GO:0000322)
0.0 0.9 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.2 GO:0032437 cuticular plate(GO:0032437)
0.0 0.4 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.2 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.1 GO:0070985 TFIIK complex(GO:0070985)
0.0 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.1 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.2 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)
0.0 0.3 GO:0031932 TORC2 complex(GO:0031932)
0.0 1.2 GO:0045095 keratin filament(GO:0045095)
0.0 3.1 GO:0030018 Z disc(GO:0030018)
0.0 0.2 GO:0005883 neurofilament(GO:0005883)
0.0 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.2 GO:0031143 pseudopodium(GO:0031143)
0.0 1.8 GO:0035579 specific granule membrane(GO:0035579)
0.0 0.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.1 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.4 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.4 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.2 0.7 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.2 1.7 GO:0051525 NFAT protein binding(GO:0051525)
0.2 0.5 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.1 0.5 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1 0.6 GO:0050436 microfibril binding(GO:0050436)
0.1 3.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.4 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 1.0 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.3 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 0.2 GO:0004103 choline kinase activity(GO:0004103)
0.1 0.4 GO:0044594 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.1 0.6 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.2 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.2 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 1.0 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 0.5 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 0.4 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.7 GO:0039706 co-receptor binding(GO:0039706) BMP receptor binding(GO:0070700)
0.0 0.5 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.5 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.4 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.2 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.6 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.2 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.1 GO:0033265 choline binding(GO:0033265)
0.0 1.2 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.2 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0 0.6 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.3 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.3 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.4 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.4 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.2 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.4 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 0.4 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.1 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.0 0.1 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.8 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.1 GO:0001855 complement component C4b binding(GO:0001855)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0004335 galactokinase activity(GO:0004335)
0.0 0.4 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.4 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.1 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 1.4 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.4 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 1.4 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.1 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.1 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.3 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.4 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.1 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.0 0.1 GO:0023025 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 1.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 0.1 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.5 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.5 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.1 GO:0004075 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.0 0.3 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.3 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.6 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.9 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.5 ST P38 MAPK PATHWAY p38 MAPK Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 1.6 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.5 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 1.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.8 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.6 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.5 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.6 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.7 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.1 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 0.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.6 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.2 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 1.8 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 3.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 1.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.1 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.5 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.1 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels