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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for NKX3-1

Z-value: 0.48

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Transcription factors associated with NKX3-1

Gene Symbol Gene ID Gene Info
NKX3-1
ENSG00000167034.9 NK3 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX3-1hg19_v2_chr8_-_23540402_235404660.106.5e-01Click!

Activity profile of NKX3-1 motif

Sorted Z-values of NKX3-1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chrX_-_19688475 0.46 ENST00000541422.1
SH3KBP1
SH3-domain kinase binding protein 1
chr4_+_70916119 0.41 ENST00000246896.3
ENST00000511674.1
HTN1
histatin 1
chr7_-_55930443 0.36 ENST00000388975.3
SEPT14
septin 14
chr20_+_18794370 0.35 ENST00000377428.2
SCP2D1
SCP2 sterol-binding domain containing 1
chr16_-_32688053 0.33 ENST00000398682.4
TP53TG3
TP53 target 3
chr16_+_32264040 0.33 ENST00000398664.3
TP53TG3D
TP53 target 3D
chr5_+_78407602 0.32 ENST00000274353.5
ENST00000524080.1
BHMT
betaine--homocysteine S-methyltransferase
chr19_+_58144529 0.28 ENST00000347302.3
ENST00000254182.7
ENST00000391703.3
ENST00000541801.1
ENST00000299871.5
ENST00000544273.1
ZNF211
zinc finger protein 211
chr10_+_135204338 0.27 ENST00000468317.2
RP11-108K14.8
Mitochondrial GTPase 1
chr9_+_134065506 0.27 ENST00000483497.2
NUP214
nucleoporin 214kDa
chr2_-_163008903 0.26 ENST00000418842.2
ENST00000375497.3
GCG
glucagon
chrX_-_51797351 0.26 ENST00000375644.3
RP11-114H20.1
RP11-114H20.1
chr12_-_43833515 0.25 ENST00000549670.1
ENST00000395541.2
ADAMTS20
ADAM metallopeptidase with thrombospondin type 1 motif, 20
chr20_-_2821756 0.25 ENST00000356872.3
ENST00000439542.1
PCED1A
PC-esterase domain containing 1A
chr20_-_2821271 0.24 ENST00000448755.1
ENST00000360652.2
PCED1A
PC-esterase domain containing 1A
chr17_-_2966901 0.24 ENST00000575751.1
OR1D5
olfactory receptor, family 1, subfamily D, member 5
chrX_+_51942963 0.24 ENST00000375625.3
RP11-363G10.2
RP11-363G10.2
chr13_+_111766897 0.22 ENST00000317133.5
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr12_+_111051902 0.22 ENST00000397655.3
ENST00000471804.2
ENST00000377654.3
ENST00000397659.4
TCTN1
tectonic family member 1
chr11_-_64684672 0.21 ENST00000377264.3
ENST00000421419.2
ATG2A
autophagy related 2A
chr12_+_111051832 0.21 ENST00000550703.2
ENST00000551590.1
TCTN1
tectonic family member 1
chr16_-_87970122 0.20 ENST00000309893.2
CA5A
carbonic anhydrase VA, mitochondrial
chr16_-_21436459 0.20 ENST00000448012.2
ENST00000504841.2
ENST00000419180.2
NPIPB3
nuclear pore complex interacting protein family, member B3
chr19_+_17186577 0.20 ENST00000595618.1
ENST00000594824.1
MYO9B
myosin IXB
chr16_+_33204156 0.20 ENST00000398667.4
TP53TG3C
TP53 target 3C
chr10_-_61900762 0.19 ENST00000355288.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr11_+_65266507 0.19 ENST00000544868.1
MALAT1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr19_+_58144589 0.19 ENST00000240731.4
ZNF211
zinc finger protein 211
chr4_-_76928641 0.19 ENST00000264888.5
CXCL9
chemokine (C-X-C motif) ligand 9
chr19_+_16308711 0.19 ENST00000429941.2
ENST00000444449.2
ENST00000589822.1
AP1M1
adaptor-related protein complex 1, mu 1 subunit
chr17_-_29624343 0.18 ENST00000247271.4
OMG
oligodendrocyte myelin glycoprotein
chr11_+_60995849 0.18 ENST00000537932.1
PGA4
pepsinogen 4, group I (pepsinogen A)
chr12_-_75603482 0.18 ENST00000341669.3
ENST00000298972.1
ENST00000350228.2
KCNC2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr6_-_144385698 0.17 ENST00000444202.1
ENST00000437412.1
PLAGL1
pleiomorphic adenoma gene-like 1
chr16_+_83986827 0.17 ENST00000393306.1
ENST00000565123.1
OSGIN1
oxidative stress induced growth inhibitor 1
chr14_+_23654525 0.17 ENST00000399910.1
ENST00000492621.1
C14orf164
chromosome 14 open reading frame 164
chr6_-_29324054 0.16 ENST00000543825.1
OR5V1
olfactory receptor, family 5, subfamily V, member 1
chr3_+_100354442 0.16 ENST00000475887.1
GPR128
G protein-coupled receptor 128
chr12_-_89919765 0.16 ENST00000541909.1
ENST00000313546.3
POC1B
POC1 centriolar protein B
chr16_-_20556492 0.16 ENST00000568098.1
ACSM2B
acyl-CoA synthetase medium-chain family member 2B
chr15_+_99645277 0.15 ENST00000336292.6
ENST00000328642.7
SYNM
synemin, intermediate filament protein
chr11_+_60163918 0.15 ENST00000526375.1
ENST00000531783.1
ENST00000395001.1
MS4A14
membrane-spanning 4-domains, subfamily A, member 14
chr4_+_76481258 0.15 ENST00000311623.4
ENST00000435974.2
C4orf26
chromosome 4 open reading frame 26
chr8_-_27168737 0.15 ENST00000521253.1
ENST00000305364.4
TRIM35
tripartite motif containing 35
chr1_-_173793458 0.15 ENST00000356198.2
CENPL
centromere protein L
chr1_-_89488510 0.15 ENST00000564665.1
ENST00000370481.4
GBP3
guanylate binding protein 3
chr19_+_17830051 0.15 ENST00000594625.1
ENST00000324096.4
ENST00000600186.1
ENST00000597735.1
MAP1S
microtubule-associated protein 1S
chr1_+_202431859 0.15 ENST00000391959.3
ENST00000367270.4
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr16_+_57406368 0.14 ENST00000006053.6
ENST00000563383.1
CX3CL1
chemokine (C-X3-C motif) ligand 1
chr7_-_138794394 0.14 ENST00000242351.5
ENST00000471652.1
ZC3HAV1
zinc finger CCCH-type, antiviral 1
chr8_-_101157680 0.14 ENST00000428847.2
FBXO43
F-box protein 43
chr10_+_5406935 0.14 ENST00000380433.3
UCN3
urocortin 3
chr12_+_113354341 0.13 ENST00000553152.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr19_-_1592652 0.13 ENST00000156825.1
ENST00000434436.3
MBD3
methyl-CpG binding domain protein 3
chr11_-_71823796 0.13 ENST00000545680.1
ENST00000543587.1
ENST00000538393.1
ENST00000535234.1
ENST00000227618.4
ENST00000535503.1
ANAPC15
anaphase promoting complex subunit 15
chr3_+_98482175 0.13 ENST00000485391.1
ENST00000492254.1
ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr16_-_69373396 0.13 ENST00000562595.1
ENST00000562081.1
ENST00000306875.4
COG8
component of oligomeric golgi complex 8
chr20_+_2821340 0.13 ENST00000380445.3
ENST00000380469.3
VPS16
vacuolar protein sorting 16 homolog (S. cerevisiae)
chr10_-_104953009 0.13 ENST00000470299.1
ENST00000343289.5
NT5C2
5'-nucleotidase, cytosolic II
chr6_+_26124373 0.13 ENST00000377791.2
ENST00000602637.1
HIST1H2AC
histone cluster 1, H2ac
chr2_+_173686303 0.12 ENST00000397087.3
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr12_-_50290839 0.12 ENST00000552863.1
FAIM2
Fas apoptotic inhibitory molecule 2
chr1_-_216596738 0.12 ENST00000307340.3
ENST00000366943.2
ENST00000366942.3
USH2A
Usher syndrome 2A (autosomal recessive, mild)
chr1_+_186798073 0.12 ENST00000367466.3
ENST00000442353.2
PLA2G4A
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr19_+_16308659 0.12 ENST00000590263.1
ENST00000590756.1
ENST00000541844.1
AP1M1
adaptor-related protein complex 1, mu 1 subunit
chr1_-_153931052 0.12 ENST00000368630.3
ENST00000368633.1
CRTC2
CREB regulated transcription coactivator 2
chr3_+_156807663 0.12 ENST00000467995.1
ENST00000474477.1
ENST00000471719.1
LINC00881
long intergenic non-protein coding RNA 881
chr10_+_32735030 0.12 ENST00000277657.6
ENST00000362006.5
CCDC7
coiled-coil domain containing 7
chr12_-_127256772 0.12 ENST00000536517.1
LINC00944
long intergenic non-protein coding RNA 944
chr11_+_9482512 0.11 ENST00000396602.2
ENST00000530463.1
ENST00000533542.1
ENST00000532577.1
ENST00000396597.3
ZNF143
zinc finger protein 143
chr6_+_42928485 0.11 ENST00000372808.3
GNMT
glycine N-methyltransferase
chr11_-_26588634 0.11 ENST00000436318.2
ENST00000281268.8
MUC15
mucin 15, cell surface associated
chr11_-_71823715 0.11 ENST00000545944.1
ENST00000502597.2
ANAPC15
anaphase promoting complex subunit 15
chr17_-_9808887 0.11 ENST00000226193.5
RCVRN
recoverin
chr5_+_96211643 0.11 ENST00000437043.3
ENST00000510373.1
ERAP2
endoplasmic reticulum aminopeptidase 2
chr11_+_94277017 0.11 ENST00000358752.2
FUT4
fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
chr16_-_3068171 0.11 ENST00000572154.1
ENST00000328796.4
CLDN6
claudin 6
chr7_+_107301065 0.10 ENST00000265715.3
SLC26A4
solute carrier family 26 (anion exchanger), member 4
chr1_-_173793246 0.10 ENST00000345664.6
ENST00000367710.3
CENPL
centromere protein L
chr3_+_132316081 0.10 ENST00000249887.2
ACKR4
atypical chemokine receptor 4
chr14_+_95078714 0.10 ENST00000393078.3
ENST00000393080.4
ENST00000467132.1
SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr17_-_295730 0.10 ENST00000329099.4
FAM101B
family with sequence similarity 101, member B
chr12_-_53045948 0.10 ENST00000309680.3
KRT2
keratin 2
chr17_-_76836963 0.10 ENST00000312010.6
USP36
ubiquitin specific peptidase 36
chr12_+_70219052 0.10 ENST00000552032.2
ENST00000547771.2
MYRFL
myelin regulatory factor-like
chr14_-_68066975 0.10 ENST00000559581.1
ENST00000560722.1
ENST00000559415.1
ENST00000216452.4
PIGH
phosphatidylinositol glycan anchor biosynthesis, class H
chr19_-_5719860 0.10 ENST00000590729.1
LONP1
lon peptidase 1, mitochondrial
chr1_+_95616933 0.10 ENST00000604203.1
RP11-57H12.6
TMEM56-RWDD3 readthrough
chr3_+_39509070 0.10 ENST00000354668.4
ENST00000428261.1
ENST00000420739.1
ENST00000415443.1
ENST00000447324.1
ENST00000383754.3
MOBP
myelin-associated oligodendrocyte basic protein
chr3_-_39196049 0.10 ENST00000514182.1
CSRNP1
cysteine-serine-rich nuclear protein 1
chr13_+_50570019 0.10 ENST00000442421.1
TRIM13
tripartite motif containing 13
chr1_-_154164534 0.10 ENST00000271850.7
ENST00000368530.2
TPM3
tropomyosin 3
chr19_-_44174330 0.10 ENST00000340093.3
PLAUR
plasminogen activator, urokinase receptor
chr12_+_110011571 0.10 ENST00000539696.1
ENST00000228510.3
ENST00000392727.3
MVK
mevalonate kinase
chr10_-_91403625 0.10 ENST00000322191.6
ENST00000342512.3
ENST00000371774.2
PANK1
pantothenate kinase 1
chr6_-_39290316 0.09 ENST00000425054.2
ENST00000373227.4
ENST00000373229.5
ENST00000437525.2
KCNK16
potassium channel, subfamily K, member 16
chr4_-_170924888 0.09 ENST00000502832.1
ENST00000393704.3
MFAP3L
microfibrillar-associated protein 3-like
chr1_+_196621156 0.09 ENST00000359637.2
CFH
complement factor H
chr5_-_160279207 0.09 ENST00000327245.5
ATP10B
ATPase, class V, type 10B
chr6_+_26020672 0.09 ENST00000357647.3
HIST1H3A
histone cluster 1, H3a
chr1_+_57320437 0.09 ENST00000361249.3
C8A
complement component 8, alpha polypeptide
chr10_+_114133773 0.09 ENST00000354655.4
ACSL5
acyl-CoA synthetase long-chain family member 5
chr8_+_128426535 0.09 ENST00000465342.2
POU5F1B
POU class 5 homeobox 1B
chr1_+_173793777 0.09 ENST00000239457.5
DARS2
aspartyl-tRNA synthetase 2, mitochondrial
chr8_+_87878640 0.09 ENST00000518476.1
CNBD1
cyclic nucleotide binding domain containing 1
chr18_+_61445007 0.08 ENST00000447428.1
ENST00000546027.1
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chrX_-_38186775 0.08 ENST00000339363.3
ENST00000309513.3
ENST00000338898.3
ENST00000342811.3
ENST00000378505.2
RPGR
retinitis pigmentosa GTPase regulator
chr10_+_46994087 0.08 ENST00000374317.1
GPRIN2
G protein regulated inducer of neurite outgrowth 2
chr3_+_52489503 0.08 ENST00000345716.4
NISCH
nischarin
chr3_-_10334585 0.08 ENST00000430179.1
ENST00000449238.2
ENST00000437422.2
ENST00000287656.7
ENST00000457360.1
ENST00000439975.2
ENST00000446937.2
GHRL
ghrelin/obestatin prepropeptide
chr16_-_31076332 0.08 ENST00000539836.3
ENST00000535577.1
ENST00000442862.2
ZNF668
zinc finger protein 668
chr17_-_64187973 0.08 ENST00000583358.1
ENST00000392769.2
CEP112
centrosomal protein 112kDa
chr12_-_49333446 0.08 ENST00000537495.1
AC073610.5
Uncharacterized protein
chr7_+_100303676 0.08 ENST00000303151.4
POP7
processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae)
chr5_+_34915444 0.08 ENST00000336767.5
BRIX1
BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)
chr11_-_62323702 0.08 ENST00000530285.1
AHNAK
AHNAK nucleoprotein
chr14_-_68066849 0.08 ENST00000558493.1
ENST00000561272.1
PIGH
phosphatidylinositol glycan anchor biosynthesis, class H
chrX_+_85403487 0.08 ENST00000373125.4
DACH2
dachshund homolog 2 (Drosophila)
chr11_-_118901559 0.08 ENST00000330775.7
ENST00000545985.1
ENST00000357590.5
ENST00000538950.1
SLC37A4
solute carrier family 37 (glucose-6-phosphate transporter), member 4
chr20_-_36661826 0.07 ENST00000373448.2
ENST00000373447.3
TTI1
TELO2 interacting protein 1
chr6_-_82462425 0.07 ENST00000369754.3
ENST00000320172.6
ENST00000369756.3
FAM46A
family with sequence similarity 46, member A
chr2_+_48541776 0.07 ENST00000413569.1
ENST00000340553.3
FOXN2
forkhead box N2
chrX_-_38186811 0.07 ENST00000318842.7
RPGR
retinitis pigmentosa GTPase regulator
chr19_+_56111680 0.07 ENST00000301073.3
ZNF524
zinc finger protein 524
chr16_-_31076273 0.07 ENST00000426488.2
ZNF668
zinc finger protein 668
chr13_+_27998681 0.07 ENST00000381140.4
GTF3A
general transcription factor IIIA
chrX_+_85403445 0.07 ENST00000373131.1
DACH2
dachshund homolog 2 (Drosophila)
chr6_-_26124138 0.07 ENST00000314332.5
ENST00000396984.1
HIST1H2BC
histone cluster 1, H2bc
chr17_+_42422662 0.07 ENST00000593167.1
ENST00000585512.1
ENST00000591740.1
ENST00000592783.1
ENST00000587387.1
ENST00000588237.1
ENST00000589265.1
GRN
granulin
chr10_+_18629628 0.07 ENST00000377329.4
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr12_+_113229543 0.07 ENST00000447659.2
RPH3A
rabphilin 3A homolog (mouse)
chr19_+_54609230 0.07 ENST00000420296.1
NDUFA3
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa
chr13_+_115000556 0.07 ENST00000252458.6
CDC16
cell division cycle 16
chr2_+_102456277 0.07 ENST00000421882.1
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr3_-_10334617 0.07 ENST00000429122.1
ENST00000425479.1
ENST00000335542.8
GHRL
ghrelin/obestatin prepropeptide
chr22_+_18632666 0.07 ENST00000215794.7
USP18
ubiquitin specific peptidase 18
chr4_+_17579110 0.07 ENST00000606142.1
LAP3
leucine aminopeptidase 3
chr6_+_43603552 0.07 ENST00000372171.4
MAD2L1BP
MAD2L1 binding protein
chr3_+_39509163 0.07 ENST00000436143.2
ENST00000441980.2
ENST00000311042.6
MOBP
myelin-associated oligodendrocyte basic protein
chr1_-_203151933 0.07 ENST00000404436.2
CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr12_+_113229452 0.07 ENST00000389385.4
RPH3A
rabphilin 3A homolog (mouse)
chr6_+_37321823 0.07 ENST00000487950.1
ENST00000469731.1
RNF8
ring finger protein 8, E3 ubiquitin protein ligase
chr5_-_176889381 0.07 ENST00000393563.4
ENST00000512501.1
DBN1
drebrin 1
chr6_-_33285505 0.07 ENST00000431845.2
ZBTB22
zinc finger and BTB domain containing 22
chr6_-_26216872 0.07 ENST00000244601.3
HIST1H2BG
histone cluster 1, H2bg
chr17_+_37824217 0.06 ENST00000394246.1
PNMT
phenylethanolamine N-methyltransferase
chr1_-_22109484 0.06 ENST00000529637.1
USP48
ubiquitin specific peptidase 48
chr1_+_46972668 0.06 ENST00000371956.4
ENST00000360032.3
DMBX1
diencephalon/mesencephalon homeobox 1
chr15_-_33360085 0.06 ENST00000334528.9
FMN1
formin 1
chr17_+_42422637 0.06 ENST00000053867.3
ENST00000588143.1
GRN
granulin
chr4_+_159131346 0.06 ENST00000508243.1
ENST00000296529.6
TMEM144
transmembrane protein 144
chrX_-_153236819 0.06 ENST00000354233.3
HCFC1
host cell factor C1 (VP16-accessory protein)
chr7_+_77325738 0.06 ENST00000334955.8
RSBN1L
round spermatid basic protein 1-like
chr14_-_59951112 0.06 ENST00000247194.4
L3HYPDH
L-3-hydroxyproline dehydratase (trans-)
chr5_+_112312416 0.06 ENST00000389063.2
DCP2
decapping mRNA 2
chr3_-_69101413 0.06 ENST00000398559.2
TMF1
TATA element modulatory factor 1
chr17_+_37824411 0.06 ENST00000269582.2
PNMT
phenylethanolamine N-methyltransferase
chr1_-_160232197 0.06 ENST00000419626.1
ENST00000610139.1
ENST00000475733.1
ENST00000407642.2
ENST00000368073.3
ENST00000326837.2
DCAF8
DDB1 and CUL4 associated factor 8
chr6_-_83775489 0.06 ENST00000369747.3
UBE3D
ubiquitin protein ligase E3D
chr9_+_116263639 0.06 ENST00000343817.5
RGS3
regulator of G-protein signaling 3
chr15_-_43877062 0.06 ENST00000381885.1
ENST00000396923.3
PPIP5K1
diphosphoinositol pentakisphosphate kinase 1
chr1_-_22109682 0.06 ENST00000400301.1
ENST00000532737.1
USP48
ubiquitin specific peptidase 48
chrX_-_153237258 0.06 ENST00000310441.7
HCFC1
host cell factor C1 (VP16-accessory protein)
chr2_-_179567206 0.06 ENST00000414766.1
TTN
titin
chr3_-_15106747 0.06 ENST00000449354.2
ENST00000444840.2
ENST00000253686.2
MRPS25
mitochondrial ribosomal protein S25
chr1_-_160232291 0.06 ENST00000368074.1
ENST00000447377.1
DCAF8
DDB1 and CUL4 associated factor 8
chr19_-_15544099 0.06 ENST00000599910.2
WIZ
widely interspaced zinc finger motifs
chr19_+_10362882 0.06 ENST00000393733.2
ENST00000588502.1
MRPL4
mitochondrial ribosomal protein L4
chr11_+_9482551 0.06 ENST00000438144.2
ENST00000526657.1
ENST00000299606.2
ENST00000534265.1
ENST00000412390.2
ZNF143
zinc finger protein 143
chr6_-_31648150 0.06 ENST00000375858.3
ENST00000383237.4
LY6G5C
lymphocyte antigen 6 complex, locus G5C
chr3_-_69101461 0.05 ENST00000543976.1
TMF1
TATA element modulatory factor 1
chr4_-_48082192 0.05 ENST00000507351.1
TXK
TXK tyrosine kinase
chr7_-_91875109 0.05 ENST00000412043.2
ENST00000430102.1
ENST00000425073.1
ENST00000394503.2
ENST00000454017.1
ENST00000440209.1
ENST00000413688.1
ENST00000452773.1
ENST00000433016.1
ENST00000394505.2
ENST00000422347.1
ENST00000458493.1
ENST00000425919.1
KRIT1
KRIT1, ankyrin repeat containing
chrX_+_153237740 0.05 ENST00000369982.4
TMEM187
transmembrane protein 187
chr9_-_14180778 0.05 ENST00000380924.1
ENST00000543693.1
NFIB
nuclear factor I/B
chr6_+_26217159 0.05 ENST00000303910.2
HIST1H2AE
histone cluster 1, H2ae
chrX_-_107681633 0.05 ENST00000394872.2
ENST00000334504.7
COL4A6
collagen, type IV, alpha 6
chr14_-_65409502 0.05 ENST00000389614.5
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr16_+_47496023 0.05 ENST00000567200.1
PHKB
phosphorylase kinase, beta
chr19_-_55791431 0.05 ENST00000593263.1
ENST00000376343.3
HSPBP1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr3_-_160117301 0.05 ENST00000326448.7
ENST00000498409.1
ENST00000475677.1
ENST00000478536.1
IFT80
intraflagellar transport 80 homolog (Chlamydomonas)
chrX_-_31285042 0.05 ENST00000378680.2
ENST00000378723.3
DMD
dystrophin
chr8_-_97247759 0.05 ENST00000518406.1
ENST00000523920.1
ENST00000287022.5
UQCRB
ubiquinol-cytochrome c reductase binding protein
chr17_-_39526052 0.05 ENST00000251646.3
KRT33B
keratin 33B
chr14_-_65409438 0.05 ENST00000557049.1
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr13_+_115000521 0.05 ENST00000252457.5
ENST00000375308.1
CDC16
cell division cycle 16
chr11_+_65337901 0.05 ENST00000309328.3
ENST00000531405.1
ENST00000527920.1
ENST00000526877.1
ENST00000533115.1
ENST00000526433.1
SSSCA1
Sjogren syndrome/scleroderma autoantigen 1
chr1_-_154832316 0.05 ENST00000361147.4
KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr16_+_55690002 0.05 ENST00000414754.3
SLC6A2
solute carrier family 6 (neurotransmitter transporter), member 2
chr8_+_30300119 0.05 ENST00000520191.1
RBPMS
RNA binding protein with multiple splicing
chrX_+_51149767 0.05 ENST00000342995.2
CXorf67
chromosome X open reading frame 67
chr4_-_70626314 0.04 ENST00000510821.1
SULT1B1
sulfotransferase family, cytosolic, 1B, member 1
chr6_-_80247105 0.04 ENST00000369846.4
LCA5
Leber congenital amaurosis 5
chr11_+_8040739 0.04 ENST00000534099.1
TUB
tubby bipartite transcription factor
chr16_+_22501658 0.04 ENST00000415833.2
NPIPB5
nuclear pore complex interacting protein family, member B5
chr6_-_123958141 0.04 ENST00000334268.4
TRDN
triadin
chr10_+_91461337 0.04 ENST00000260753.4
ENST00000416354.1
ENST00000394289.2
ENST00000371728.3
KIF20B
kinesin family member 20B
chr7_+_110731062 0.04 ENST00000308478.5
ENST00000451085.1
ENST00000422987.3
ENST00000421101.1
LRRN3
leucine rich repeat neuronal 3
chr11_-_61687739 0.04 ENST00000531922.1
ENST00000301773.5
RAB3IL1
RAB3A interacting protein (rabin3)-like 1
chr17_+_68100989 0.04 ENST00000585558.1
ENST00000392670.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX3-1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
0.1 0.3 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.1 0.4 GO:1904491 somatic motor neuron differentiation(GO:0021523) protein localization to ciliary transition zone(GO:1904491)
0.1 0.2 GO:0040010 positive regulation of growth rate(GO:0040010) regulation of gastric mucosal blood circulation(GO:1904344) positive regulation of gastric mucosal blood circulation(GO:1904346) gastric mucosal blood circulation(GO:1990768)
0.0 0.2 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.1 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.0 0.2 GO:0031443 fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.0 0.1 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.1 GO:0042418 epinephrine biosynthetic process(GO:0042418)
0.0 0.1 GO:0019046 release from viral latency(GO:0019046)
0.0 0.1 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.1 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.1 GO:2000845 testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
0.0 0.2 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.1 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.0 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650)
0.0 0.2 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.2 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.3 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
0.0 0.2 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.1 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.0 0.3 GO:0043485 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.0 0.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.1 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.2 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.2 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.2 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.0 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.0 GO:1903436 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.1 0.2 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.0 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 0.2 GO:0097486 multivesicular body lumen(GO:0097486)
0.0 0.1 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.1 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0047150 betaine-homocysteine S-methyltransferase activity(GO:0047150)
0.1 0.2 GO:0031768 ghrelin receptor binding(GO:0031768)
0.0 0.1 GO:0004603 phenylethanolamine N-methyltransferase activity(GO:0004603)
0.0 0.1 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.0 0.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.1 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 0.1 GO:0070362 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.0 0.1 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 0.1 GO:0016855 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0070984 SET domain binding(GO:0070984)
0.0 0.2 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.0 GO:0005330 dopamine:sodium symporter activity(GO:0005330)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.1 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.1 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.0 GO:0008112 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.3 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide