Project

Inflammatory response time course, HUVEC (Wada et al., 2009)

Navigation
Downloads

Results for NKX3-2

Z-value: 1.05

Motif logo

logo of

Transcription factors associated with NKX3-2

Gene Symbol Gene ID Gene Info
NKX3-2
ENSG00000109705.7 NK3 homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX3-2hg19_v2_chr4_-_13546632_13546674-0.272.0e-01Click!

Activity profile of NKX3-2 motif

Sorted Z-values of NKX3-2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_156588249 7.73 ENST00000393832.3
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr4_+_156587979 6.27 ENST00000511507.1
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr4_+_156588115 4.79 ENST00000455639.2
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr4_+_156588350 3.61 ENST00000296518.7
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr4_+_156680518 2.48 ENST00000513437.1
GUCY1B3
guanylate cyclase 1, soluble, beta 3
chr10_+_35415719 2.28 ENST00000474362.1
ENST00000374721.3
CREM
cAMP responsive element modulator
chr10_-_131762105 2.13 ENST00000368648.3
ENST00000355311.5
EBF3
early B-cell factor 3
chr10_+_35415978 1.97 ENST00000429130.3
ENST00000469949.2
ENST00000460270.1
CREM
cAMP responsive element modulator
chr10_+_35416090 1.92 ENST00000354759.3
CREM
cAMP responsive element modulator
chr2_-_208489707 1.91 ENST00000448007.2
ENST00000432416.1
ENST00000411432.1
METTL21A
methyltransferase like 21A
chr2_-_188312971 1.91 ENST00000410068.1
ENST00000447403.1
ENST00000410102.1
CALCRL
calcitonin receptor-like
chr17_-_67138015 1.90 ENST00000284425.2
ENST00000590645.1
ABCA6
ATP-binding cassette, sub-family A (ABC1), member 6
chr7_+_155090271 1.83 ENST00000476756.1
INSIG1
insulin induced gene 1
chr2_-_220435963 1.80 ENST00000373876.1
ENST00000404537.1
ENST00000603926.1
ENST00000373873.4
ENST00000289656.3
OBSL1
obscurin-like 1
chr2_-_208489275 1.76 ENST00000272839.3
ENST00000426075.1
METTL21A
methyltransferase like 21A
chr9_-_124976154 1.68 ENST00000482062.1
LHX6
LIM homeobox 6
chr9_-_124976185 1.68 ENST00000464484.2
LHX6
LIM homeobox 6
chr14_+_61789382 1.65 ENST00000555082.1
PRKCH
protein kinase C, eta
chr5_+_68710906 1.62 ENST00000325631.5
ENST00000454295.2
MARVELD2
MARVEL domain containing 2
chr10_+_35416223 1.51 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
CREM
cAMP responsive element modulator
chr15_+_89402148 1.51 ENST00000560601.1
ACAN
aggrecan
chr11_+_64879317 1.49 ENST00000526809.1
ENST00000279263.7
ENST00000524986.1
ENST00000534371.1
ENST00000540748.1
ENST00000525385.1
ENST00000345348.5
ENST00000531321.1
ENST00000529414.1
ENST00000526085.1
ENST00000530750.1
TM7SF2
transmembrane 7 superfamily member 2
chr9_-_75567962 1.48 ENST00000297785.3
ENST00000376939.1
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr3_+_132316081 1.38 ENST00000249887.2
ACKR4
atypical chemokine receptor 4
chr3_+_193853927 1.35 ENST00000232424.3
HES1
hes family bHLH transcription factor 1
chr17_+_58755184 1.28 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
BCAS3
breast carcinoma amplified sequence 3
chr7_-_120498357 1.24 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
TSPAN12
tetraspanin 12
chr16_-_49890016 1.23 ENST00000563137.2
ZNF423
zinc finger protein 423
chr4_+_144257915 1.22 ENST00000262995.4
GAB1
GRB2-associated binding protein 1
chr2_-_220436248 1.18 ENST00000265318.4
OBSL1
obscurin-like 1
chr16_-_28222797 1.18 ENST00000569951.1
ENST00000565698.1
XPO6
exportin 6
chr4_-_159080806 1.16 ENST00000590648.1
FAM198B
family with sequence similarity 198, member B
chr4_+_144258021 1.13 ENST00000262994.4
GAB1
GRB2-associated binding protein 1
chr9_+_134065506 1.08 ENST00000483497.2
NUP214
nucleoporin 214kDa
chr15_-_52944231 1.08 ENST00000546305.2
FAM214A
family with sequence similarity 214, member A
chr19_+_1026566 1.06 ENST00000348419.3
ENST00000565096.2
ENST00000562958.2
ENST00000562075.2
ENST00000607102.1
CNN2
calponin 2
chr12_-_42983478 1.02 ENST00000345127.3
ENST00000547113.1
PRICKLE1
prickle homolog 1 (Drosophila)
chr12_-_10022735 1.00 ENST00000228438.2
CLEC2B
C-type lectin domain family 2, member B
chr4_+_144303093 1.00 ENST00000505913.1
GAB1
GRB2-associated binding protein 1
chr1_+_162351503 0.99 ENST00000458626.2
C1orf226
chromosome 1 open reading frame 226
chr15_+_99645277 0.99 ENST00000336292.6
ENST00000328642.7
SYNM
synemin, intermediate filament protein
chr12_-_50616122 0.95 ENST00000552823.1
ENST00000552909.1
LIMA1
LIM domain and actin binding 1
chrX_+_51928002 0.92 ENST00000375626.3
MAGED4
melanoma antigen family D, 4
chr9_+_116263778 0.91 ENST00000394646.3
RGS3
regulator of G-protein signaling 3
chr17_-_39968406 0.87 ENST00000393928.1
LEPREL4
leprecan-like 4
chr11_-_102401469 0.82 ENST00000260227.4
MMP7
matrix metallopeptidase 7 (matrilysin, uterine)
chrX_+_100333709 0.78 ENST00000372930.4
TMEM35
transmembrane protein 35
chr8_+_70404996 0.77 ENST00000402687.4
ENST00000419716.3
SULF1
sulfatase 1
chrX_+_38420783 0.75 ENST00000422612.2
ENST00000286824.6
ENST00000545599.1
TSPAN7
tetraspanin 7
chr19_+_18544045 0.75 ENST00000599699.2
SSBP4
single stranded DNA binding protein 4
chr11_-_67290867 0.75 ENST00000353903.5
ENST00000294288.4
CABP2
calcium binding protein 2
chr17_-_39968855 0.74 ENST00000355468.3
ENST00000590496.1
LEPREL4
leprecan-like 4
chr19_-_38916839 0.74 ENST00000433821.2
ENST00000426920.2
ENST00000587753.1
ENST00000454404.2
ENST00000293062.9
RASGRP4
RAS guanyl releasing protein 4
chr9_+_35906176 0.73 ENST00000354323.2
HRCT1
histidine rich carboxyl terminus 1
chr3_-_52008016 0.73 ENST00000489595.2
ENST00000461108.1
ENST00000395008.2
ENST00000525795.1
ENST00000361143.5
RP11-155D18.14
ABHD14B
Poly(rC)-binding protein 4
abhydrolase domain containing 14B
chr9_+_116263639 0.72 ENST00000343817.5
RGS3
regulator of G-protein signaling 3
chr6_-_31697255 0.70 ENST00000436437.1
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr21_-_35899113 0.69 ENST00000492600.1
ENST00000481448.1
ENST00000381132.2
RCAN1
regulator of calcineurin 1
chr7_+_115862858 0.67 ENST00000393481.2
TES
testis derived transcript (3 LIM domains)
chr19_-_3028354 0.67 ENST00000586422.1
TLE2
transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr14_+_21156915 0.67 ENST00000397990.4
ENST00000555597.1
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr21_-_33984865 0.66 ENST00000458138.1
C21orf59
chromosome 21 open reading frame 59
chr6_-_31697977 0.66 ENST00000375787.2
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr17_-_32690239 0.66 ENST00000225842.3
CCL1
chemokine (C-C motif) ligand 1
chr3_+_50192537 0.65 ENST00000002829.3
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr19_-_6459746 0.64 ENST00000301454.4
ENST00000334510.5
SLC25A23
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
chr16_-_28223166 0.62 ENST00000304658.5
XPO6
exportin 6
chr21_-_33984888 0.61 ENST00000382549.4
ENST00000540881.1
C21orf59
chromosome 21 open reading frame 59
chr12_-_50616382 0.61 ENST00000552783.1
LIMA1
LIM domain and actin binding 1
chr6_-_31697563 0.60 ENST00000375789.2
ENST00000416410.1
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr3_+_124303472 0.60 ENST00000291478.5
KALRN
kalirin, RhoGEF kinase
chr1_+_66258846 0.60 ENST00000341517.4
PDE4B
phosphodiesterase 4B, cAMP-specific
chr3_+_50192499 0.59 ENST00000413852.1
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr2_-_70780572 0.59 ENST00000450929.1
TGFA
transforming growth factor, alpha
chr20_-_2821271 0.57 ENST00000448755.1
ENST00000360652.2
PCED1A
PC-esterase domain containing 1A
chr16_-_24942411 0.57 ENST00000571843.1
ARHGAP17
Rho GTPase activating protein 17
chr1_+_151739131 0.56 ENST00000400999.1
OAZ3
ornithine decarboxylase antizyme 3
chr6_-_32731243 0.56 ENST00000427449.1
ENST00000411527.1
HLA-DQB2
major histocompatibility complex, class II, DQ beta 2
chr16_-_24942273 0.53 ENST00000571406.1
ARHGAP17
Rho GTPase activating protein 17
chr19_+_41313017 0.53 ENST00000595621.1
ENST00000595051.1
EGLN2
egl-9 family hypoxia-inducible factor 2
chr5_+_169780485 0.52 ENST00000377360.4
KCNIP1
Kv channel interacting protein 1
chr3_+_196366555 0.52 ENST00000328557.4
NRROS
negative regulator of reactive oxygen species
chr21_-_33985127 0.52 ENST00000290155.3
C21orf59
chromosome 21 open reading frame 59
chr19_+_17337473 0.50 ENST00000598068.1
OCEL1
occludin/ELL domain containing 1
chr11_-_76381029 0.49 ENST00000407242.2
ENST00000421973.1
LRRC32
leucine rich repeat containing 32
chr12_-_80084862 0.49 ENST00000328827.4
PAWR
PRKC, apoptosis, WT1, regulator
chr16_-_27561209 0.49 ENST00000356183.4
ENST00000561623.1
GTF3C1
general transcription factor IIIC, polypeptide 1, alpha 220kDa
chr19_+_1026298 0.48 ENST00000263097.4
CNN2
calponin 2
chrX_-_119695279 0.48 ENST00000336592.6
CUL4B
cullin 4B
chr17_-_19771216 0.48 ENST00000395544.4
ULK2
unc-51 like autophagy activating kinase 2
chr9_-_74979420 0.46 ENST00000343431.2
ENST00000376956.3
ZFAND5
zinc finger, AN1-type domain 5
chr15_-_37393406 0.46 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2
Meis homeobox 2
chr16_+_3019552 0.45 ENST00000572687.1
PAQR4
progestin and adipoQ receptor family member IV
chr19_-_46526304 0.45 ENST00000008938.4
PGLYRP1
peptidoglycan recognition protein 1
chr19_-_51920873 0.44 ENST00000441969.3
ENST00000525998.1
ENST00000436984.2
SIGLEC10
sialic acid binding Ig-like lectin 10
chr17_+_34171081 0.44 ENST00000585577.1
TAF15
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
chr15_-_56035177 0.44 ENST00000389286.4
ENST00000561292.1
PRTG
protogenin
chr20_-_2821756 0.43 ENST00000356872.3
ENST00000439542.1
PCED1A
PC-esterase domain containing 1A
chr19_-_38747172 0.43 ENST00000347262.4
ENST00000591585.1
ENST00000301242.4
PPP1R14A
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr20_+_42984330 0.41 ENST00000316673.4
ENST00000609795.1
ENST00000457232.1
ENST00000609262.1
HNF4A
hepatocyte nuclear factor 4, alpha
chr2_+_136289030 0.41 ENST00000409478.1
ENST00000264160.4
ENST00000329971.3
ENST00000438014.1
R3HDM1
R3H domain containing 1
chr19_+_14672755 0.41 ENST00000594545.1
TECR
trans-2,3-enoyl-CoA reductase
chr1_+_6845497 0.41 ENST00000473578.1
ENST00000557126.1
CAMTA1
calmodulin binding transcription activator 1
chr1_+_93544821 0.40 ENST00000370303.4
MTF2
metal response element binding transcription factor 2
chr14_-_68066849 0.40 ENST00000558493.1
ENST00000561272.1
PIGH
phosphatidylinositol glycan anchor biosynthesis, class H
chr6_-_32731299 0.40 ENST00000435145.2
ENST00000437316.2
HLA-DQB2
major histocompatibility complex, class II, DQ beta 2
chrX_+_153656978 0.40 ENST00000369762.2
ENST00000422890.1
ATP6AP1
ATPase, H+ transporting, lysosomal accessory protein 1
chr1_-_156399184 0.39 ENST00000368243.1
ENST00000357975.4
ENST00000310027.5
ENST00000400991.2
C1orf61
chromosome 1 open reading frame 61
chr2_+_242167319 0.39 ENST00000601871.1
AC104841.2
HCG1777198, isoform CRA_a; PRO2900; Uncharacterized protein
chr5_+_169931009 0.38 ENST00000328939.4
ENST00000390656.4
KCNIP1
Kv channel interacting protein 1
chr1_+_93544791 0.38 ENST00000545708.1
ENST00000540243.1
ENST00000370298.4
MTF2
metal response element binding transcription factor 2
chr6_+_5261730 0.38 ENST00000274680.4
FARS2
phenylalanyl-tRNA synthetase 2, mitochondrial
chr9_+_35161998 0.37 ENST00000396787.1
ENST00000378495.3
ENST00000378496.4
UNC13B
unc-13 homolog B (C. elegans)
chr3_+_69134124 0.37 ENST00000478935.1
ARL6IP5
ADP-ribosylation-like factor 6 interacting protein 5
chr10_+_72238517 0.36 ENST00000263563.6
PALD1
phosphatase domain containing, paladin 1
chr11_-_22851367 0.36 ENST00000354193.4
SVIP
small VCP/p97-interacting protein
chr19_+_36545833 0.36 ENST00000401500.2
ENST00000270301.7
ENST00000427823.2
WDR62
WD repeat domain 62
chr4_+_123300591 0.36 ENST00000439307.1
ENST00000388724.2
ADAD1
adenosine deaminase domain containing 1 (testis-specific)
chr16_+_3194211 0.35 ENST00000428155.1
CASP16
caspase 16, apoptosis-related cysteine peptidase (putative)
chr12_+_15699286 0.35 ENST00000442921.2
ENST00000542557.1
ENST00000445537.2
ENST00000544244.1
PTPRO
protein tyrosine phosphatase, receptor type, O
chr19_+_16435625 0.35 ENST00000248071.5
ENST00000592003.1
KLF2
Kruppel-like factor 2
chr1_+_6845578 0.35 ENST00000467404.2
ENST00000439411.2
CAMTA1
calmodulin binding transcription activator 1
chr7_-_128415844 0.35 ENST00000249389.2
OPN1SW
opsin 1 (cone pigments), short-wave-sensitive
chr4_+_159727272 0.35 ENST00000379346.3
FNIP2
folliculin interacting protein 2
chr11_-_63381823 0.35 ENST00000323646.5
PLA2G16
phospholipase A2, group XVI
chr5_-_137514288 0.34 ENST00000454473.1
ENST00000418329.1
ENST00000455658.2
ENST00000230901.5
ENST00000402931.1
BRD8
bromodomain containing 8
chr16_+_4743707 0.34 ENST00000586536.1
ENST00000405142.1
ENST00000590460.1
NUDT16L1
nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1
chr6_+_32121218 0.34 ENST00000414204.1
ENST00000361568.2
ENST00000395523.1
PPT2
palmitoyl-protein thioesterase 2
chr11_-_19082216 0.34 ENST00000329773.2
MRGPRX2
MAS-related GPR, member X2
chr7_-_8276508 0.34 ENST00000401396.1
ENST00000317367.5
ICA1
islet cell autoantigen 1, 69kDa
chr5_-_137514333 0.34 ENST00000411594.2
ENST00000430331.1
BRD8
bromodomain containing 8
chrX_+_48660287 0.34 ENST00000444343.2
ENST00000376610.2
ENST00000334136.5
ENST00000376619.2
HDAC6
histone deacetylase 6
chr14_-_106830057 0.33 ENST00000390616.2
IGHV4-34
immunoglobulin heavy variable 4-34
chr17_-_62308087 0.33 ENST00000583097.1
TEX2
testis expressed 2
chr2_-_25016251 0.33 ENST00000328379.5
PTRHD1
peptidyl-tRNA hydrolase domain containing 1
chr17_+_68071389 0.33 ENST00000283936.1
ENST00000392671.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr17_-_43487780 0.33 ENST00000532038.1
ENST00000528677.1
ARHGAP27
Rho GTPase activating protein 27
chr10_+_23384435 0.32 ENST00000376510.3
MSRB2
methionine sulfoxide reductase B2
chr19_-_3061397 0.32 ENST00000586839.1
AES
amino-terminal enhancer of split
chr19_-_36545649 0.32 ENST00000292894.1
THAP8
THAP domain containing 8
chr17_-_46507537 0.31 ENST00000336915.6
SKAP1
src kinase associated phosphoprotein 1
chr8_+_42396274 0.31 ENST00000438528.3
SMIM19
small integral membrane protein 19
chr15_+_75639951 0.31 ENST00000564784.1
ENST00000569035.1
NEIL1
nei endonuclease VIII-like 1 (E. coli)
chr5_+_169931249 0.30 ENST00000520740.1
KCNIP1
Kv channel interacting protein 1
chr5_+_140810132 0.30 ENST00000252085.3
PCDHGA12
protocadherin gamma subfamily A, 12
chr14_+_50779071 0.30 ENST00000426751.2
ATP5S
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
chr22_-_31328881 0.30 ENST00000445980.1
MORC2
MORC family CW-type zinc finger 2
chr6_-_30080863 0.30 ENST00000540829.1
TRIM31
tripartite motif containing 31
chr1_-_154832316 0.30 ENST00000361147.4
KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr22_+_44568825 0.30 ENST00000422871.1
PARVG
parvin, gamma
chr16_-_86542652 0.29 ENST00000599749.1
FENDRR
FOXF1 adjacent non-coding developmental regulatory RNA
chr12_+_71833756 0.29 ENST00000536515.1
ENST00000540815.2
LGR5
leucine-rich repeat containing G protein-coupled receptor 5
chr3_-_51813009 0.29 ENST00000398780.3
IQCF6
IQ motif containing F6
chr3_+_169629354 0.29 ENST00000428432.2
ENST00000335556.3
SAMD7
sterile alpha motif domain containing 7
chr9_-_131940526 0.29 ENST00000372491.2
IER5L
immediate early response 5-like
chr19_-_36297348 0.29 ENST00000589835.1
PRODH2
proline dehydrogenase (oxidase) 2
chr6_-_39290316 0.29 ENST00000425054.2
ENST00000373227.4
ENST00000373229.5
ENST00000437525.2
KCNK16
potassium channel, subfamily K, member 16
chr2_+_25016282 0.29 ENST00000260662.1
CENPO
centromere protein O
chr3_+_111697843 0.29 ENST00000534857.1
ENST00000273359.3
ENST00000494817.1
ABHD10
abhydrolase domain containing 10
chr4_+_75023816 0.28 ENST00000395759.2
ENST00000331145.6
ENST00000359107.5
ENST00000325278.6
MTHFD2L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
chr12_+_53693466 0.28 ENST00000267103.5
ENST00000548632.1
C12orf10
chromosome 12 open reading frame 10
chr9_-_131644202 0.28 ENST00000320665.6
ENST00000436267.2
CCBL1
cysteine conjugate-beta lyase, cytoplasmic
chr7_-_107642348 0.28 ENST00000393561.1
LAMB1
laminin, beta 1
chr1_+_35247859 0.27 ENST00000373362.3
GJB3
gap junction protein, beta 3, 31kDa
chr10_-_49459800 0.27 ENST00000305531.3
FRMPD2
FERM and PDZ domain containing 2
chr2_+_62132800 0.27 ENST00000538736.1
COMMD1
copper metabolism (Murr1) domain containing 1
chr5_+_68711209 0.27 ENST00000512803.1
MARVELD2
MARVEL domain containing 2
chr18_-_46987000 0.27 ENST00000442713.2
ENST00000269445.6
DYM
dymeclin
chr4_-_76861392 0.26 ENST00000505594.1
NAAA
N-acylethanolamine acid amidase
chr14_+_35591735 0.26 ENST00000604948.1
ENST00000605201.1
ENST00000250377.7
ENST00000321130.10
ENST00000534898.4
KIAA0391
KIAA0391
chr22_-_41636929 0.26 ENST00000216241.9
CHADL
chondroadherin-like
chr12_+_104982622 0.26 ENST00000549016.1
CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr19_-_51920952 0.26 ENST00000356298.5
ENST00000339313.5
ENST00000529627.1
ENST00000439889.2
ENST00000353836.5
ENST00000432469.2
SIGLEC10
sialic acid binding Ig-like lectin 10
chr11_+_66045634 0.25 ENST00000528852.1
ENST00000311445.6
CNIH2
cornichon family AMPA receptor auxiliary protein 2
chr19_-_51920835 0.25 ENST00000442846.3
ENST00000530476.1
SIGLEC10
sialic acid binding Ig-like lectin 10
chr16_-_67517716 0.25 ENST00000290953.2
AGRP
agouti related protein homolog (mouse)
chr20_+_2276639 0.25 ENST00000381458.5
TGM3
transglutaminase 3
chr14_-_74551172 0.25 ENST00000553458.1
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr14_-_98444386 0.25 ENST00000556462.1
ENST00000556138.1
C14orf64
chromosome 14 open reading frame 64
chr19_-_6393216 0.25 ENST00000595047.1
GTF2F1
general transcription factor IIF, polypeptide 1, 74kDa
chr5_+_64859066 0.24 ENST00000261308.5
ENST00000535264.1
ENST00000538977.1
PPWD1
peptidylprolyl isomerase domain and WD repeat containing 1
chr5_-_36152031 0.24 ENST00000296603.4
LMBRD2
LMBR1 domain containing 2
chr1_-_48866517 0.24 ENST00000371841.1
SPATA6
spermatogenesis associated 6
chr3_+_69134080 0.24 ENST00000273258.3
ARL6IP5
ADP-ribosylation-like factor 6 interacting protein 5
chr7_+_99971129 0.24 ENST00000394000.2
ENST00000350573.2
PILRA
paired immunoglobin-like type 2 receptor alpha
chr7_+_129007964 0.24 ENST00000460109.1
ENST00000474594.1
ENST00000446212.1
AHCYL2
adenosylhomocysteinase-like 2
chr12_-_113658892 0.23 ENST00000299732.2
ENST00000416617.2
IQCD
IQ motif containing D
chr17_-_42295870 0.23 ENST00000526094.1
ENST00000529383.1
ENST00000530828.1
UBTF
upstream binding transcription factor, RNA polymerase I
chr16_-_30457048 0.23 ENST00000500504.2
ENST00000542752.1
SEPHS2
selenophosphate synthetase 2
chr16_-_47177874 0.23 ENST00000562435.1
NETO2
neuropilin (NRP) and tolloid (TLL)-like 2
chr2_+_102927962 0.22 ENST00000233954.1
ENST00000393393.3
ENST00000410040.1
IL1RL1
IL18R1
interleukin 1 receptor-like 1
interleukin 18 receptor 1
chr12_-_120765565 0.22 ENST00000423423.3
ENST00000308366.4
PLA2G1B
phospholipase A2, group IB (pancreas)
chr11_+_67250490 0.22 ENST00000528641.2
ENST00000279146.3
AIP
aryl hydrocarbon receptor interacting protein
chr20_+_54987305 0.22 ENST00000371336.3
ENST00000434344.1
CASS4
Cas scaffolding protein family member 4
chr19_-_18548921 0.22 ENST00000545187.1
ENST00000578352.1
ISYNA1
inositol-3-phosphate synthase 1
chr20_+_59654146 0.21 ENST00000441660.1
RP5-827L5.1
RP5-827L5.1
chr8_-_16035454 0.21 ENST00000355282.2
MSR1
macrophage scavenger receptor 1
chr2_-_27294500 0.21 ENST00000447619.1
ENST00000429985.1
ENST00000456793.1
OST4
oligosaccharyltransferase 4 homolog (S. cerevisiae)
chr11_-_26593649 0.21 ENST00000455601.2
MUC15
mucin 15, cell surface associated
chr4_-_84205905 0.21 ENST00000311461.7
ENST00000311469.4
ENST00000439031.2
COQ2
coenzyme Q2 4-hydroxybenzoate polyprenyltransferase

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX3-2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 22.4 GO:0052551 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.6 1.8 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.5 1.4 GO:0021558 trochlear nerve development(GO:0021558) negative regulation of auditory receptor cell differentiation(GO:0045608) regulation of timing of neuron differentiation(GO:0060164)
0.4 1.5 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.3 2.5 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.3 3.4 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.3 1.0 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.2 1.0 GO:0031443 fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.2 0.8 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.2 1.9 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.2 1.6 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.2 1.2 GO:0035290 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.2 2.7 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.4 GO:0051714 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.1 0.8 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 0.5 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.1 0.4 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1 0.4 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 0.6 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 0.9 GO:0032431 activation of phospholipase A2 activity(GO:0032431)
0.1 1.9 GO:0006527 arginine catabolic process(GO:0006527)
0.1 7.0 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 3.4 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.1 0.6 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.1 0.3 GO:0090035 regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.1 0.3 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 0.3 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.1 0.6 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 1.5 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 0.2 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.1 0.4 GO:2000302 regulation of synaptic vesicle priming(GO:0010807) positive regulation of synaptic vesicle exocytosis(GO:2000302)
0.1 0.3 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.1 0.3 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.1 0.2 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.1 0.2 GO:0052314 phytoalexin metabolic process(GO:0052314)
0.1 0.2 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.1 0.5 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.1 0.5 GO:0075044 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.1 0.2 GO:0051257 meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.1 0.4 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 0.4 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.1 0.2 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.1 0.2 GO:0048867 ganglion mother cell fate determination(GO:0007402) stem cell fate determination(GO:0048867)
0.1 0.4 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.4 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.3 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.8 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.2 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 1.0 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.2 GO:0051344 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.3 GO:2001033 negative regulation of double-strand break repair via nonhomologous end joining(GO:2001033)
0.0 0.5 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 1.0 GO:0044849 estrous cycle(GO:0044849)
0.0 0.2 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.4 GO:0030497 fatty acid elongation(GO:0030497)
0.0 0.5 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.2 GO:0006021 inositol biosynthetic process(GO:0006021)
0.0 1.6 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 1.2 GO:0010842 retina layer formation(GO:0010842)
0.0 0.6 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.3 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)
0.0 0.3 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.3 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 0.4 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.2 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.0 0.5 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 2.7 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.6 GO:0001780 neutrophil homeostasis(GO:0001780)
0.0 0.3 GO:0030091 protein repair(GO:0030091)
0.0 0.3 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 0.1 GO:1904219 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.3 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.1 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.0 0.7 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.2 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.0 0.1 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 1.8 GO:0031529 ruffle organization(GO:0031529)
0.0 0.3 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 3.1 GO:0043462 regulation of ATPase activity(GO:0043462)
0.0 0.3 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.7 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.1 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0 0.1 GO:0060059 female genitalia morphogenesis(GO:0048807) embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0 0.6 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.3 GO:0048703 embryonic viscerocranium morphogenesis(GO:0048703)
0.0 0.3 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 1.5 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 0.1 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.0 0.2 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.1 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0 0.2 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.0 0.3 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.0 0.9 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.7 GO:0050427 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.2 GO:0015889 cobalamin transport(GO:0015889)
0.0 1.5 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0 0.4 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.5 GO:0048745 smooth muscle tissue development(GO:0048745)
0.0 0.4 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.1 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 1.0 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.2 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.2 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.2 GO:0042048 olfactory behavior(GO:0042048)
0.0 0.2 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.5 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.4 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.8 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 0.2 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.1 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.5 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.2 GO:0008272 sulfate transport(GO:0008272)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 24.8 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.5 1.8 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.4 3.0 GO:1990393 3M complex(GO:1990393)
0.4 1.1 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.3 1.0 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.2 1.9 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.7 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 0.3 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.1 0.3 GO:0005607 laminin-2 complex(GO:0005607)
0.1 0.4 GO:0044305 calyx of Held(GO:0044305)
0.1 0.4 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.1 0.6 GO:0005787 signal peptidase complex(GO:0005787)
0.1 0.5 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 0.5 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.2 GO:0097224 sperm connecting piece(GO:0097224)
0.1 0.2 GO:0005715 late recombination nodule(GO:0005715)
0.1 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.2 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.2 GO:0031213 RSF complex(GO:0031213)
0.0 0.3 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 1.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.4 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.5 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.7 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.3 GO:0097486 multivesicular body lumen(GO:0097486)
0.0 3.2 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.4 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.8 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.5 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.5 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.2 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.6 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.2 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 1.5 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.5 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 2.0 GO:0005796 Golgi lumen(GO:0005796)
0.0 6.1 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.1 GO:0036157 outer dynein arm(GO:0036157)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 24.8 GO:0004383 guanylate cyclase activity(GO:0004383)
0.5 1.5 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.5 1.9 GO:0004948 calcitonin receptor activity(GO:0004948)
0.5 7.7 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.4 1.3 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.3 1.6 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.3 1.5 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.3 2.0 GO:0016403 dimethylargininase activity(GO:0016403)
0.2 0.5 GO:0001003 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.1 0.8 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.7 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.6 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 0.4 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.1 3.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.4 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.1 0.7 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 0.3 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.1 0.3 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.1 0.3 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.1 1.2 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.2 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.1 1.0 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.2 GO:0002113 interleukin-33 binding(GO:0002113)
0.1 0.3 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.3 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 0.2 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.1 0.2 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.1 1.0 GO:0019215 intermediate filament binding(GO:0019215)
0.1 3.7 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 0.3 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.3 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 0.4 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 0.3 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 3.5 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.1 1.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.2 GO:0070051 fibrinogen binding(GO:0070051)
0.0 1.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.7 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.6 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.2 GO:0001007 transcription factor activity, RNA polymerase III transcription factor binding(GO:0001007)
0.0 0.6 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 1.8 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.2 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.5 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 1.4 GO:0019956 chemokine binding(GO:0019956)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.5 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.3 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.3 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.2 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 1.5 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.0 0.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.0 0.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.4 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.2 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.2 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.4 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.3 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.0 0.5 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.4 GO:0017166 vinculin binding(GO:0017166)
0.0 0.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.3 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.0 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.3 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.2 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 8.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 3.4 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 1.8 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 2.3 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.6 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 1.4 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.4 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.8 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.5 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.8 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 24.2 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.1 1.5 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 3.4 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.1 1.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.9 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.7 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 1.7 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.6 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.6 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 1.1 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 0.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.4 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.5 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.4 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.2 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.1 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.7 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere