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Inflammatory response time course, HUVEC (Wada et al., 2009)
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Results for NKX6-3
Z-value: 0.18
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Transcription factors associated with NKX6-3
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
NKX6-3
|
ENSG00000165066.11 | NK6 homeobox 3 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| NKX6-3 | hg19_v2_chr8_-_41504878_41504878 | -0.22 | 2.9e-01 | Click! |
Activity profile of NKX6-3 motif
Sorted Z-values of NKX6-3 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr3_-_141747950 | 0.20 |
ENST00000497579.1
|
TFDP2
|
transcription factor Dp-2 (E2F dimerization partner 2) |
| chr8_-_90769422 | 0.17 |
ENST00000524190.1
ENST00000523859.1 |
RP11-37B2.1
|
RP11-37B2.1 |
| chr20_+_11008811 | 0.16 |
ENST00000537362.1
|
C20orf187
|
chromosome 20 open reading frame 187 |
| chr20_-_29978286 | 0.13 |
ENST00000376315.2
|
DEFB119
|
defensin, beta 119 |
| chr14_+_88852059 | 0.10 |
ENST00000045347.7
|
SPATA7
|
spermatogenesis associated 7 |
| chr4_+_76481258 | 0.10 |
ENST00000311623.4
ENST00000435974.2 |
C4orf26
|
chromosome 4 open reading frame 26 |
| chr4_-_123542224 | 0.10 |
ENST00000264497.3
|
IL21
|
interleukin 21 |
| chr5_-_58295712 | 0.10 |
ENST00000317118.8
|
PDE4D
|
phosphodiesterase 4D, cAMP-specific |
| chr3_-_191000172 | 0.09 |
ENST00000427544.2
|
UTS2B
|
urotensin 2B |
| chr14_+_88851874 | 0.09 |
ENST00000393545.4
ENST00000356583.5 ENST00000555401.1 ENST00000553885.1 |
SPATA7
|
spermatogenesis associated 7 |
| chr13_+_53602894 | 0.09 |
ENST00000219022.2
|
OLFM4
|
olfactomedin 4 |
| chr1_+_160370344 | 0.08 |
ENST00000368061.2
|
VANGL2
|
VANGL planar cell polarity protein 2 |
| chr6_+_130339710 | 0.07 |
ENST00000526087.1
ENST00000533560.1 ENST00000361794.2 |
L3MBTL3
|
l(3)mbt-like 3 (Drosophila) |
| chrX_-_110655306 | 0.07 |
ENST00000371993.2
|
DCX
|
doublecortin |
| chr9_+_125132803 | 0.07 |
ENST00000540753.1
|
PTGS1
|
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| chrX_+_43515467 | 0.05 |
ENST00000338702.3
ENST00000542639.1 |
MAOA
|
monoamine oxidase A |
| chr4_+_80584903 | 0.05 |
ENST00000506460.1
|
RP11-452C8.1
|
RP11-452C8.1 |
| chr17_-_10372875 | 0.04 |
ENST00000255381.2
|
MYH4
|
myosin, heavy chain 4, skeletal muscle |
| chr17_+_4692230 | 0.04 |
ENST00000331264.7
|
GLTPD2
|
glycolipid transfer protein domain containing 2 |
| chr16_-_67517716 | 0.04 |
ENST00000290953.2
|
AGRP
|
agouti related protein homolog (mouse) |
| chr7_+_138145076 | 0.03 |
ENST00000343526.4
|
TRIM24
|
tripartite motif containing 24 |
| chr17_-_64225508 | 0.03 |
ENST00000205948.6
|
APOH
|
apolipoprotein H (beta-2-glycoprotein I) |
| chr19_+_4402659 | 0.03 |
ENST00000301280.5
ENST00000585854.1 |
CHAF1A
|
chromatin assembly factor 1, subunit A (p150) |
| chr9_+_125133315 | 0.03 |
ENST00000223423.4
ENST00000362012.2 |
PTGS1
|
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| chr13_-_81801115 | 0.02 |
ENST00000567258.1
|
LINC00564
|
long intergenic non-protein coding RNA 564 |
| chr3_+_138340067 | 0.02 |
ENST00000479848.1
|
FAIM
|
Fas apoptotic inhibitory molecule |
| chr11_+_22689648 | 0.02 |
ENST00000278187.3
|
GAS2
|
growth arrest-specific 2 |
| chr8_+_92261516 | 0.02 |
ENST00000276609.3
ENST00000309536.2 |
SLC26A7
|
solute carrier family 26 (anion exchanger), member 7 |
| chr3_+_138340049 | 0.02 |
ENST00000464668.1
|
FAIM
|
Fas apoptotic inhibitory molecule |
| chr1_-_151431647 | 0.01 |
ENST00000368863.2
ENST00000409503.1 ENST00000491586.1 ENST00000533351.1 ENST00000540984.1 |
POGZ
|
pogo transposable element with ZNF domain |
| chr6_-_9933500 | 0.01 |
ENST00000492169.1
|
OFCC1
|
orofacial cleft 1 candidate 1 |
| chr20_+_11008408 | 0.01 |
ENST00000378252.1
|
C20orf187
|
chromosome 20 open reading frame 187 |
| chr20_+_30697298 | 0.01 |
ENST00000398022.2
|
TM9SF4
|
transmembrane 9 superfamily protein member 4 |
| chr5_-_139726181 | 0.00 |
ENST00000507104.1
ENST00000230990.6 |
HBEGF
|
heparin-binding EGF-like growth factor |
| chr1_-_151431909 | 0.00 |
ENST00000361398.3
ENST00000271715.2 |
POGZ
|
pogo transposable element with ZNF domain |
| chr1_-_208417620 | 0.00 |
ENST00000367033.3
|
PLXNA2
|
plexin A2 |
| chr11_-_13517565 | 0.00 |
ENST00000282091.1
ENST00000529816.1 |
PTH
|
parathyroid hormone |
Network of associatons between targets according to the STRING database.
First level regulatory network of NKX6-3
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | GO:0060490 | orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346) |
| 0.0 | 0.2 | GO:1903546 | protein localization to photoreceptor outer segment(GO:1903546) |
| 0.0 | 0.1 | GO:2000389 | regulation of neutrophil extravasation(GO:2000389) |
| 0.0 | 0.1 | GO:0086024 | adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | GO:0060187 | cell pole(GO:0060187) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | GO:0004666 | prostaglandin-endoperoxide synthase activity(GO:0004666) |
| 0.0 | 0.1 | GO:0005134 | interleukin-2 receptor binding(GO:0005134) |