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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for NOTO_VSX2_DLX2_DLX6_NKX6-1

Z-value: 0.67

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Transcription factors associated with NOTO_VSX2_DLX2_DLX6_NKX6-1

Gene Symbol Gene ID Gene Info
NOTO
ENSG00000214513.3 notochord homeobox
VSX2
ENSG00000119614.2 visual system homeobox 2
DLX2
ENSG00000115844.6 distal-less homeobox 2
DLX6
ENSG00000006377.9 distal-less homeobox 6
NKX6-1
ENSG00000163623.5 NK6 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
DLX6hg19_v2_chr7_+_96635277_96635301,
hg19_v2_chr7_+_96634850_96634874		0.203.3e-01Click!
DLX2hg19_v2_chr2_-_172967621_172967637-0.203.5e-01Click!
NKX6-1hg19_v2_chr4_-_85419603_854196030.125.8e-01Click!

Activity profile of NOTO_VSX2_DLX2_DLX6_NKX6-1 motif

Sorted Z-values of NOTO_VSX2_DLX2_DLX6_NKX6-1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_32157947 1.70 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr1_+_74701062 1.51 ENST00000326637.3
TNNI3K
TNNI3 interacting kinase
chr4_-_138453606 1.39 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
PCDH18
protocadherin 18
chr10_-_48416849 1.17 ENST00000249598.1
GDF2
growth differentiation factor 2
chr4_-_186696425 0.98 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
SORBS2
sorbin and SH3 domain containing 2
chr6_+_130339710 0.90 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr7_-_14029283 0.85 ENST00000433547.1
ENST00000405192.2
ETV1
ets variant 1
chr11_-_33913708 0.84 ENST00000257818.2
LMO2
LIM domain only 2 (rhombotin-like 1)
chr17_-_39150385 0.83 ENST00000391586.1
KRTAP3-3
keratin associated protein 3-3
chr3_+_111718036 0.78 ENST00000455401.2
TAGLN3
transgelin 3
chr11_-_31531121 0.75 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMMP1L
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr14_-_54423529 0.74 ENST00000245451.4
ENST00000559087.1
BMP4
bone morphogenetic protein 4
chr4_+_41614909 0.73 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1
LIM and calponin homology domains 1
chr17_+_47448102 0.72 ENST00000576461.1
RP11-81K2.1
Uncharacterized protein
chr21_+_17442799 0.67 ENST00000602580.1
ENST00000458468.1
ENST00000602935.1
LINC00478
long intergenic non-protein coding RNA 478
chr12_-_16761007 0.67 ENST00000354662.1
ENST00000441439.2
LMO3
LIM domain only 3 (rhombotin-like 2)
chr3_+_111717600 0.66 ENST00000273368.4
TAGLN3
transgelin 3
chr1_+_61548225 0.64 ENST00000371187.3
NFIA
nuclear factor I/A
chr3_+_111717511 0.64 ENST00000478951.1
ENST00000393917.2
TAGLN3
transgelin 3
chr2_-_68052694 0.63 ENST00000457448.1
AC010987.6
AC010987.6
chr21_-_31538971 0.56 ENST00000286808.3
CLDN17
claudin 17
chr3_-_74570291 0.55 ENST00000263665.6
CNTN3
contactin 3 (plasmacytoma associated)
chr11_-_129062093 0.54 ENST00000310343.9
ARHGAP32
Rho GTPase activating protein 32
chrX_-_19688475 0.54 ENST00000541422.1
SH3KBP1
SH3-domain kinase binding protein 1
chr4_+_71108300 0.54 ENST00000304954.3
CSN3
casein kappa
chr1_+_61547894 0.51 ENST00000403491.3
NFIA
nuclear factor I/A
chr21_+_17443521 0.51 ENST00000456342.1
LINC00478
long intergenic non-protein coding RNA 478
chr7_+_73442457 0.50 ENST00000438880.1
ENST00000414324.1
ENST00000380562.4
ELN
elastin
chr21_+_17443434 0.48 ENST00000400178.2
LINC00478
long intergenic non-protein coding RNA 478
chr7_-_130080977 0.47 ENST00000223208.5
CEP41
centrosomal protein 41kDa
chr21_+_17909594 0.47 ENST00000441820.1
ENST00000602280.1
LINC00478
long intergenic non-protein coding RNA 478
chr19_-_56110859 0.46 ENST00000221665.3
ENST00000592585.1
FIZ1
FLT3-interacting zinc finger 1
chr7_+_73442422 0.46 ENST00000358929.4
ENST00000431562.1
ENST00000320492.7
ENST00000438906.1
ELN
elastin
chr17_-_46690839 0.46 ENST00000498634.2
HOXB8
homeobox B8
chr7_+_73442102 0.46 ENST00000445912.1
ENST00000252034.7
ELN
elastin
chr6_-_76203345 0.45 ENST00000393004.2
FILIP1
filamin A interacting protein 1
chr11_+_20620946 0.44 ENST00000525748.1
SLC6A5
solute carrier family 6 (neurotransmitter transporter), member 5
chr6_-_76203454 0.43 ENST00000237172.7
FILIP1
filamin A interacting protein 1
chr17_-_40337470 0.43 ENST00000293330.1
HCRT
hypocretin (orexin) neuropeptide precursor
chr7_-_107642348 0.42 ENST00000393561.1
LAMB1
laminin, beta 1
chr7_-_14028488 0.41 ENST00000405358.4
ETV1
ets variant 1
chr11_-_69633792 0.40 ENST00000334134.2
FGF3
fibroblast growth factor 3
chr7_+_73442487 0.40 ENST00000380575.4
ENST00000380584.4
ENST00000458204.1
ENST00000357036.5
ENST00000417091.1
ENST00000429192.1
ENST00000442310.1
ENST00000380553.4
ENST00000380576.5
ENST00000428787.1
ENST00000320399.6
ELN
elastin
chr4_+_41614720 0.40 ENST00000509277.1
LIMCH1
LIM and calponin homology domains 1
chr1_-_152131703 0.39 ENST00000316073.3
RPTN
repetin
chr12_-_14133053 0.39 ENST00000609686.1
GRIN2B
glutamate receptor, ionotropic, N-methyl D-aspartate 2B
chr12_-_30887948 0.38 ENST00000433722.2
CAPRIN2
caprin family member 2
chr5_+_174151536 0.38 ENST00000239243.6
ENST00000507785.1
MSX2
msh homeobox 2
chr1_+_61548374 0.38 ENST00000485903.2
ENST00000371185.2
ENST00000371184.2
NFIA
nuclear factor I/A
chr9_+_136501478 0.38 ENST00000393056.2
ENST00000263611.2
DBH
dopamine beta-hydroxylase (dopamine beta-monooxygenase)
chr2_+_234826016 0.36 ENST00000324695.4
ENST00000433712.2
TRPM8
transient receptor potential cation channel, subfamily M, member 8
chr2_+_169757750 0.35 ENST00000375363.3
ENST00000429379.2
ENST00000421979.1
G6PC2
glucose-6-phosphatase, catalytic, 2
chr1_-_234667504 0.35 ENST00000421207.1
ENST00000435574.1
RP5-855F14.1
RP5-855F14.1
chr3_-_178984759 0.35 ENST00000349697.2
ENST00000497599.1
KCNMB3
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr11_+_124481361 0.34 ENST00000284288.2
PANX3
pannexin 3
chr11_+_34663913 0.34 ENST00000532302.1
EHF
ets homologous factor
chr13_-_99910673 0.34 ENST00000397473.2
ENST00000397470.2
GPR18
G protein-coupled receptor 18
chr13_+_36050881 0.33 ENST00000537702.1
NBEA
neurobeachin
chr7_-_14026123 0.32 ENST00000420159.2
ENST00000399357.3
ENST00000403527.1
ETV1
ets variant 1
chr2_-_183291741 0.32 ENST00000351439.5
ENST00000409365.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr6_+_132873832 0.32 ENST00000275200.1
TAAR8
trace amine associated receptor 8
chr16_+_69345243 0.31 ENST00000254950.11
VPS4A
vacuolar protein sorting 4 homolog A (S. cerevisiae)
chr5_+_176811431 0.31 ENST00000512593.1
ENST00000324417.5
SLC34A1
solute carrier family 34 (type II sodium/phosphate contransporter), member 1
chr13_-_36050819 0.31 ENST00000379919.4
MAB21L1
mab-21-like 1 (C. elegans)
chr4_+_88529681 0.30 ENST00000399271.1
DSPP
dentin sialophosphoprotein
chr7_-_71868354 0.29 ENST00000412588.1
CALN1
calneuron 1
chr7_-_14029515 0.29 ENST00000430479.1
ENST00000405218.2
ENST00000343495.5
ETV1
ets variant 1
chr15_+_80351910 0.29 ENST00000261749.6
ENST00000561060.1
ZFAND6
zinc finger, AN1-type domain 6
chr19_-_14064114 0.29 ENST00000585607.1
ENST00000538517.2
ENST00000587458.1
ENST00000538371.2
PODNL1
podocan-like 1
chr11_+_7618413 0.29 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr19_-_7968427 0.28 ENST00000539278.1
AC010336.1
Uncharacterized protein
chr2_-_70780572 0.28 ENST00000450929.1
TGFA
transforming growth factor, alpha
chr7_+_99717230 0.28 ENST00000262932.3
CNPY4
canopy FGF signaling regulator 4
chrX_-_64196351 0.27 ENST00000374839.3
ZC4H2
zinc finger, C4H2 domain containing
chr8_-_25281747 0.27 ENST00000421054.2
GNRH1
gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
chr4_-_41884620 0.27 ENST00000504870.1
LINC00682
long intergenic non-protein coding RNA 682
chr12_+_28410128 0.27 ENST00000381259.1
ENST00000381256.1
CCDC91
coiled-coil domain containing 91
chr8_-_93115445 0.27 ENST00000523629.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chrX_-_64196376 0.27 ENST00000447788.2
ZC4H2
zinc finger, C4H2 domain containing
chr12_+_52695617 0.27 ENST00000293525.5
KRT86
keratin 86
chrX_-_64196307 0.26 ENST00000545618.1
ZC4H2
zinc finger, C4H2 domain containing
chrX_-_10851762 0.25 ENST00000380785.1
ENST00000380787.1
MID1
midline 1 (Opitz/BBB syndrome)
chr9_+_2159850 0.25 ENST00000416751.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr14_-_92413727 0.25 ENST00000267620.10
FBLN5
fibulin 5
chr6_+_136172820 0.25 ENST00000308191.6
PDE7B
phosphodiesterase 7B
chr4_-_123542224 0.25 ENST00000264497.3
IL21
interleukin 21
chr16_+_24741013 0.25 ENST00000315183.7
ENST00000395799.3
TNRC6A
trinucleotide repeat containing 6A
chr21_-_40033618 0.25 ENST00000417133.2
ENST00000398910.1
ENST00000442448.1
ERG
v-ets avian erythroblastosis virus E26 oncogene homolog
chr2_-_182545603 0.25 ENST00000295108.3
NEUROD1
neuronal differentiation 1
chr12_-_16759711 0.25 ENST00000447609.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr1_+_62439037 0.24 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr2_+_190541153 0.24 ENST00000313581.4
ENST00000438402.2
ENST00000431575.2
ENST00000281412.6
ANKAR
ankyrin and armadillo repeat containing
chr1_+_61547405 0.24 ENST00000371189.4
NFIA
nuclear factor I/A
chr3_-_12587055 0.23 ENST00000564146.3
C3orf83
chromosome 3 open reading frame 83
chr6_-_26235206 0.23 ENST00000244534.5
HIST1H1D
histone cluster 1, H1d
chr15_-_37393406 0.23 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2
Meis homeobox 2
chrX_-_18690210 0.23 ENST00000379984.3
RS1
retinoschisin 1
chr14_+_61654271 0.23 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
PRKCH
protein kinase C, eta
chr11_-_8290263 0.23 ENST00000428101.2
LMO1
LIM domain only 1 (rhombotin 1)
chr7_-_80141328 0.23 ENST00000398291.3
GNAT3
guanine nucleotide binding protein, alpha transducing 3
chr17_-_27418537 0.23 ENST00000408971.2
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr4_+_159727272 0.22 ENST00000379346.3
FNIP2
folliculin interacting protein 2
chr3_+_173116225 0.22 ENST00000457714.1
NLGN1
neuroligin 1
chr1_-_45956800 0.22 ENST00000538496.1
TESK2
testis-specific kinase 2
chr7_+_141478242 0.22 ENST00000247881.2
TAS2R4
taste receptor, type 2, member 4
chr13_-_110438914 0.22 ENST00000375856.3
IRS2
insulin receptor substrate 2
chr16_-_4852915 0.21 ENST00000322048.7
ROGDI
rogdi homolog (Drosophila)
chr6_+_72922590 0.21 ENST00000523963.1
RIMS1
regulating synaptic membrane exocytosis 1
chr6_+_72922505 0.21 ENST00000401910.3
RIMS1
regulating synaptic membrane exocytosis 1
chr16_+_76587314 0.21 ENST00000563764.1
RP11-58C22.1
Uncharacterized protein
chr11_-_102576537 0.21 ENST00000260229.4
MMP27
matrix metallopeptidase 27
chr15_+_96869165 0.21 ENST00000421109.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr9_+_125132803 0.21 ENST00000540753.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr3_-_27764190 0.20 ENST00000537516.1
EOMES
eomesodermin
chrX_-_19817869 0.20 ENST00000379698.4
SH3KBP1
SH3-domain kinase binding protein 1
chr11_+_34664014 0.20 ENST00000527935.1
EHF
ets homologous factor
chr9_+_12693336 0.20 ENST00000381137.2
ENST00000388918.5
TYRP1
tyrosinase-related protein 1
chr11_+_5410607 0.20 ENST00000328611.3
OR51M1
olfactory receptor, family 51, subfamily M, member 1
chr6_-_33160231 0.20 ENST00000395194.1
ENST00000457788.1
ENST00000341947.2
ENST00000357486.1
ENST00000374714.1
ENST00000374713.1
ENST00000395197.1
ENST00000374712.1
ENST00000361917.1
ENST00000374708.4
COL11A2
collagen, type XI, alpha 2
chrX_+_10031499 0.19 ENST00000454666.1
WWC3
WWC family member 3
chrX_-_73512411 0.19 ENST00000602576.1
ENST00000429124.1
FTX
FTX transcript, XIST regulator (non-protein coding)
chr13_+_78315466 0.19 ENST00000314070.5
ENST00000462234.1
SLAIN1
SLAIN motif family, member 1
chr2_+_162272605 0.19 ENST00000389554.3
TBR1
T-box, brain, 1
chr12_+_54378923 0.19 ENST00000303460.4
HOXC10
homeobox C10
chr16_+_81678957 0.19 ENST00000398040.4
CMIP
c-Maf inducing protein
chr9_-_139965000 0.19 ENST00000409687.3
SAPCD2
suppressor APC domain containing 2
chr15_+_67841330 0.19 ENST00000354498.5
MAP2K5
mitogen-activated protein kinase kinase 5
chr16_+_53133070 0.18 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr17_+_42634844 0.18 ENST00000315323.3
FZD2
frizzled family receptor 2
chr7_+_138145076 0.18 ENST00000343526.4
TRIM24
tripartite motif containing 24
chr7_+_116660246 0.18 ENST00000434836.1
ENST00000393443.1
ENST00000465133.1
ENST00000477742.1
ENST00000393447.4
ENST00000393444.3
ST7
suppression of tumorigenicity 7
chrX_+_99839799 0.18 ENST00000373031.4
TNMD
tenomodulin
chr6_-_76072719 0.18 ENST00000370020.1
FILIP1
filamin A interacting protein 1
chr7_-_27205136 0.18 ENST00000396345.1
ENST00000343483.6
HOXA9
homeobox A9
chr21_+_17792672 0.18 ENST00000602620.1
LINC00478
long intergenic non-protein coding RNA 478
chr4_+_77356248 0.18 ENST00000296043.6
SHROOM3
shroom family member 3
chrX_-_153599578 0.18 ENST00000360319.4
ENST00000344736.4
FLNA
filamin A, alpha
chr1_-_68698222 0.18 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
WLS
wntless Wnt ligand secretion mediator
chr9_-_136933134 0.18 ENST00000303407.7
BRD3
bromodomain containing 3
chr6_+_105404899 0.18 ENST00000345080.4
LIN28B
lin-28 homolog B (C. elegans)
chr6_-_39693111 0.17 ENST00000373215.3
ENST00000538893.1
ENST00000287152.7
ENST00000373216.3
KIF6
kinesin family member 6
chr9_-_14314518 0.17 ENST00000397581.2
NFIB
nuclear factor I/B
chr1_+_206557366 0.17 ENST00000414007.1
ENST00000419187.2
SRGAP2
SLIT-ROBO Rho GTPase activating protein 2
chr9_-_14314566 0.17 ENST00000397579.2
NFIB
nuclear factor I/B
chr18_+_46065393 0.17 ENST00000256413.3
CTIF
CBP80/20-dependent translation initiation factor
chr3_-_191000172 0.17 ENST00000427544.2
UTS2B
urotensin 2B
chr22_+_46449674 0.16 ENST00000381051.2
FLJ27365
hsa-mir-4763
chr12_+_20963647 0.16 ENST00000381545.3
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr7_-_14026063 0.16 ENST00000443608.1
ENST00000438956.1
ETV1
ets variant 1
chr9_+_77230499 0.16 ENST00000396204.2
RORB
RAR-related orphan receptor B
chr1_-_190446759 0.16 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr12_+_20963632 0.16 ENST00000540853.1
ENST00000261196.2
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr17_+_73452545 0.16 ENST00000314256.7
KIAA0195
KIAA0195
chr12_-_68696652 0.16 ENST00000539972.1
MDM1
Mdm1 nuclear protein homolog (mouse)
chr17_+_18086392 0.16 ENST00000541285.1
ALKBH5
alkB, alkylation repair homolog 5 (E. coli)
chr2_+_163175394 0.16 ENST00000446271.1
ENST00000429691.2
GCA
grancalcin, EF-hand calcium binding protein
chr1_+_180601139 0.16 ENST00000367590.4
ENST00000367589.3
XPR1
xenotropic and polytropic retrovirus receptor 1
chr4_+_90033968 0.16 ENST00000317005.2
TIGD2
tigger transposable element derived 2
chr12_+_19358228 0.15 ENST00000424268.1
ENST00000543806.1
PLEKHA5
pleckstrin homology domain containing, family A member 5
chr5_+_61874562 0.15 ENST00000334994.5
ENST00000409534.1
LRRC70
IPO11
leucine rich repeat containing 70
importin 11
chr13_+_78315295 0.15 ENST00000351546.3
SLAIN1
SLAIN motif family, member 1
chr19_-_47137942 0.15 ENST00000300873.4
GNG8
guanine nucleotide binding protein (G protein), gamma 8
chr14_+_22977587 0.15 ENST00000390504.1
TRAJ33
T cell receptor alpha joining 33
chr7_+_148287657 0.15 ENST00000307003.2
C7orf33
chromosome 7 open reading frame 33
chr17_-_46716647 0.15 ENST00000608940.1
RP11-357H14.17
RP11-357H14.17
chr22_-_32860427 0.15 ENST00000534972.1
ENST00000397450.1
ENST00000397452.1
BPIFC
BPI fold containing family C
chr10_+_119301928 0.14 ENST00000553456.3
EMX2
empty spiracles homeobox 2
chr6_-_111136513 0.14 ENST00000368911.3
CDK19
cyclin-dependent kinase 19
chr9_-_215744 0.14 ENST00000382387.2
C9orf66
chromosome 9 open reading frame 66
chr15_+_80351977 0.14 ENST00000559157.1
ENST00000561012.1
ENST00000564367.1
ENST00000558494.1
ZFAND6
zinc finger, AN1-type domain 6
chr3_-_114790179 0.14 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr19_-_7698599 0.14 ENST00000311069.5
PCP2
Purkinje cell protein 2
chr9_+_125133315 0.14 ENST00000223423.4
ENST00000362012.2
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr12_-_76817036 0.14 ENST00000546946.1
OSBPL8
oxysterol binding protein-like 8
chr9_-_95166884 0.14 ENST00000375561.5
OGN
osteoglycin
chr5_+_31193847 0.14 ENST00000514738.1
ENST00000265071.2
CDH6
cadherin 6, type 2, K-cadherin (fetal kidney)
chr14_+_88852059 0.14 ENST00000045347.7
SPATA7
spermatogenesis associated 7
chr4_+_88532028 0.14 ENST00000282478.7
DSPP
dentin sialophosphoprotein
chr1_+_153746683 0.13 ENST00000271857.2
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chr7_-_143599207 0.13 ENST00000355951.2
ENST00000479870.1
ENST00000478172.1
FAM115A
family with sequence similarity 115, member A
chr7_-_83278322 0.13 ENST00000307792.3
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr4_-_177116772 0.13 ENST00000280191.2
SPATA4
spermatogenesis associated 4
chr6_-_111804905 0.13 ENST00000358835.3
ENST00000435970.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr1_-_45956822 0.13 ENST00000372086.3
ENST00000341771.6
TESK2
testis-specific kinase 2
chr2_+_210444142 0.13 ENST00000360351.4
ENST00000361559.4
MAP2
microtubule-associated protein 2
chr15_+_58702742 0.13 ENST00000356113.6
ENST00000414170.3
LIPC
lipase, hepatic
chr13_-_67802549 0.13 ENST00000328454.5
ENST00000377865.2
PCDH9
protocadherin 9
chr14_-_92413353 0.13 ENST00000556154.1
FBLN5
fibulin 5
chr1_+_40713573 0.13 ENST00000372766.3
TMCO2
transmembrane and coiled-coil domains 2
chr8_+_26150628 0.13 ENST00000523925.1
ENST00000315985.7
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr18_-_24129367 0.13 ENST00000408011.3
KCTD1
potassium channel tetramerization domain containing 1
chr9_-_95166841 0.13 ENST00000262551.4
OGN
osteoglycin
chr6_-_51952418 0.13 ENST00000371117.3
PKHD1
polycystic kidney and hepatic disease 1 (autosomal recessive)
chr11_-_124190184 0.13 ENST00000357438.2
OR8D2
olfactory receptor, family 8, subfamily D, member 2
chrX_-_10645773 0.13 ENST00000453318.2
MID1
midline 1 (Opitz/BBB syndrome)
chr10_+_94594351 0.13 ENST00000371552.4
EXOC6
exocyst complex component 6
chr15_+_91411810 0.12 ENST00000268171.3
FURIN
furin (paired basic amino acid cleaving enzyme)
chr6_-_161695042 0.12 ENST00000366908.5
ENST00000366911.5
ENST00000366905.3
AGPAT4
1-acylglycerol-3-phosphate O-acyltransferase 4
chr15_+_75080883 0.12 ENST00000567571.1
CSK
c-src tyrosine kinase
chr11_-_40315640 0.12 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C

Network of associatons between targets according to the STRING database.

First level regulatory network of NOTO_VSX2_DLX2_DLX6_NKX6-1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:2000004 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.2 0.2 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.2 0.9 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1 0.4 GO:0090427 positive regulation of catagen(GO:0051795) activation of meiosis(GO:0090427)
0.1 0.3 GO:2000118 dentinogenesis(GO:0097187) regulation of sodium-dependent phosphate transport(GO:2000118)
0.1 0.4 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.1 0.4 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.1 0.7 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 0.3 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.1 0.3 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 2.1 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 0.2 GO:0099545 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.1 0.4 GO:0050955 thermoception(GO:0050955)
0.1 1.8 GO:0072189 ureter development(GO:0072189)
0.1 0.4 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 0.9 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.4 GO:0035881 amacrine cell differentiation(GO:0035881)
0.1 0.3 GO:1990637 response to prolactin(GO:1990637)
0.1 1.5 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.1 0.3 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.1 0.2 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.1 1.2 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 0.4 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.1 0.2 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.1 0.2 GO:0009956 radial pattern formation(GO:0009956)
0.1 1.8 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.3 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.3 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.5 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.2 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.2 GO:0050916 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.0 0.1 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) negative regulation of neurotrophin production(GO:0032900) negative regulation of transforming growth factor beta1 production(GO:0032911)
0.0 0.2 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 1.0 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0 0.2 GO:0060023 soft palate development(GO:0060023)
0.0 0.1 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0 0.2 GO:0010746 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0 0.4 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.2 GO:0021764 amygdala development(GO:0021764)
0.0 0.3 GO:0034214 protein hexamerization(GO:0034214)
0.0 1.1 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.2 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.3 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.0 0.6 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.1 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 0.1 GO:1900222 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) negative regulation of beta-amyloid clearance(GO:1900222) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.0 0.1 GO:0051866 general adaptation syndrome(GO:0051866)
0.0 0.2 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.1 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.0 0.1 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.1 GO:0007113 endomitotic cell cycle(GO:0007113)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.1 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.2 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.2 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.5 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.2 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0 0.1 GO:1902081 regulation of the force of heart contraction by cardiac conduction(GO:0086092) regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.0 0.2 GO:2000852 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.0 2.0 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 0.1 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.0 0.1 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.0 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.4 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.2 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.0 GO:0003213 cardiac right atrium morphogenesis(GO:0003213)
0.0 0.3 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.2 GO:0060022 hard palate development(GO:0060022)
0.0 0.1 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.0 0.3 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.3 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.7 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 0.2 GO:0009642 response to light intensity(GO:0009642)
0.0 0.6 GO:0007625 grooming behavior(GO:0007625)
0.0 0.2 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.1 GO:0045404 negative regulation of tolerance induction(GO:0002644) interleukin-4 biosynthetic process(GO:0042097) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.6 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.2 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.2 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.1 GO:1900248 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.0 0.1 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.0 0.1 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.0 0.1 GO:0042997 negative regulation of low-density lipoprotein particle clearance(GO:0010989) negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.1 GO:1904383 response to sodium phosphate(GO:1904383) response to insulin-like growth factor stimulus(GO:1990418)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.4 GO:0072662 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.1 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.2 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0 0.3 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.1 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.0 0.1 GO:0007144 female meiosis I(GO:0007144)
0.0 0.2 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.0 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0 0.2 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.4 GO:0055026 negative regulation of cardiac muscle tissue development(GO:0055026)
0.0 0.1 GO:0071400 cellular response to oleic acid(GO:0071400)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.0 GO:0031296 positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296)
0.0 0.1 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.0 0.1 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.1 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.9 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.0 0.1 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.4 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.2 GO:1902224 ketone body metabolic process(GO:1902224)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.2 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.2 2.2 GO:0071953 elastic fiber(GO:0071953)
0.1 0.4 GO:0005607 laminin-2 complex(GO:0005607)
0.1 0.2 GO:0031523 Myb complex(GO:0031523)
0.0 0.4 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.1 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.0 0.3 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.1 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.1 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.2 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.2 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 GO:0031013 troponin I binding(GO:0031013)
0.1 0.4 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 0.4 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 0.3 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.3 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.1 0.8 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.4 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1 0.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.3 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.2 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.3 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.2 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.2 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.4 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.1 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.0 0.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.3 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.3 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.1 GO:0019770 IgG receptor activity(GO:0019770)
0.0 0.1 GO:0016608 growth hormone-releasing hormone activity(GO:0016608)
0.0 0.2 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.0 0.1 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.0 0.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 3.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 0.2 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.1 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 0.1 GO:0032093 SAM domain binding(GO:0032093)
0.0 0.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 1.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 1.2 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.2 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.1 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.2 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.1 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.0 GO:0005173 stem cell factor receptor binding(GO:0005173)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.2 PID ALK1 PATHWAY ALK1 signaling events
0.0 2.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.4 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.3 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.5 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.8 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.9 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.4 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.3 REACTOME GPCR DOWNSTREAM SIGNALING Genes involved in GPCR downstream signaling
0.0 0.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.2 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.3 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination