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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for NR0B1

Z-value: 0.73

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Transcription factors associated with NR0B1

Gene Symbol Gene ID Gene Info
NR0B1
ENSG00000169297.6 nuclear receptor subfamily 0 group B member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR0B1hg19_v2_chrX_-_30327495_30327509,
hg19_v2_chrX_-_30326445_30326605		0.232.7e-01Click!

Activity profile of NR0B1 motif

Sorted Z-values of NR0B1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_+_71320557 2.73 ENST00000541509.1
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr7_+_89841144 1.97 ENST00000394622.2
ENST00000394632.1
ENST00000426158.1
ENST00000394621.2
ENST00000402625.2
STEAP2
STEAP family member 2, metalloreductase
chr7_+_89841024 1.94 ENST00000394626.1
STEAP2
STEAP family member 2, metalloreductase
chr1_+_212458834 1.85 ENST00000261461.2
PPP2R5A
protein phosphatase 2, regulatory subunit B', alpha
chr22_+_51112800 1.80 ENST00000414786.2
SHANK3
SH3 and multiple ankyrin repeat domains 3
chr18_-_22932080 1.78 ENST00000584787.1
ENST00000361524.3
ENST00000538137.2
ZNF521
zinc finger protein 521
chr15_-_52970820 1.77 ENST00000261844.7
ENST00000399202.4
ENST00000562135.1
FAM214A
family with sequence similarity 214, member A
chr9_+_128509624 1.66 ENST00000342287.5
ENST00000373487.4
PBX3
pre-B-cell leukemia homeobox 3
chr4_-_90758227 1.63 ENST00000506691.1
ENST00000394986.1
ENST00000506244.1
ENST00000394989.2
ENST00000394991.3
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr4_-_90758118 1.45 ENST00000420646.2
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr2_-_152684977 1.39 ENST00000428992.2
ENST00000295087.8
ARL5A
ADP-ribosylation factor-like 5A
chr12_+_56661461 1.28 ENST00000546544.1
ENST00000553234.1
COQ10A
coenzyme Q10 homolog A (S. cerevisiae)
chr13_-_52027134 1.19 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6
integrator complex subunit 6
chr5_+_61708582 1.15 ENST00000325324.6
IPO11
importin 11
chr11_-_2160180 1.14 ENST00000381406.4
IGF2
insulin-like growth factor 2 (somatomedin A)
chr1_-_147245484 1.11 ENST00000271348.2
GJA5
gap junction protein, alpha 5, 40kDa
chr17_+_42634844 1.09 ENST00000315323.3
FZD2
frizzled family receptor 2
chr1_+_211432700 1.03 ENST00000452621.2
RCOR3
REST corepressor 3
chr4_-_135122903 1.00 ENST00000421491.3
ENST00000529122.2
PABPC4L
poly(A) binding protein, cytoplasmic 4-like
chr16_+_4845379 1.00 ENST00000588606.1
ENST00000586005.1
SMIM22
small integral membrane protein 22
chr1_+_110754094 0.96 ENST00000369787.3
ENST00000413138.3
ENST00000438661.2
KCNC4
potassium voltage-gated channel, Shaw-related subfamily, member 4
chr3_-_169381183 0.96 ENST00000494292.1
MECOM
MDS1 and EVI1 complex locus
chr14_-_23822061 0.95 ENST00000397260.3
SLC22A17
solute carrier family 22, member 17
chr7_+_2559399 0.94 ENST00000222725.5
ENST00000359574.3
LFNG
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr2_+_170683979 0.88 ENST00000418381.1
UBR3
ubiquitin protein ligase E3 component n-recognin 3 (putative)
chr6_-_111804905 0.87 ENST00000358835.3
ENST00000435970.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr9_+_128509663 0.84 ENST00000373489.5
ENST00000373483.2
PBX3
pre-B-cell leukemia homeobox 3
chr19_+_35842445 0.83 ENST00000246553.2
FFAR1
free fatty acid receptor 1
chr6_-_111804393 0.82 ENST00000368802.3
ENST00000368805.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr16_+_89894875 0.81 ENST00000393062.2
SPIRE2
spire-type actin nucleation factor 2
chr14_-_23822080 0.81 ENST00000397267.1
ENST00000354772.3
SLC22A17
solute carrier family 22, member 17
chr19_-_2050852 0.81 ENST00000541165.1
ENST00000591601.1
MKNK2
MAP kinase interacting serine/threonine kinase 2
chr4_+_88928777 0.80 ENST00000237596.2
PKD2
polycystic kidney disease 2 (autosomal dominant)
chr12_+_57482665 0.79 ENST00000300131.3
NAB2
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr20_+_306177 0.79 ENST00000544632.1
SOX12
SRY (sex determining region Y)-box 12
chr15_-_82338460 0.79 ENST00000558133.1
ENST00000329713.4
MEX3B
mex-3 RNA binding family member B
chr2_+_170683942 0.78 ENST00000272793.5
UBR3
ubiquitin protein ligase E3 component n-recognin 3 (putative)
chrX_-_119695279 0.77 ENST00000336592.6
CUL4B
cullin 4B
chr12_+_56661033 0.77 ENST00000433805.2
COQ10A
coenzyme Q10 homolog A (S. cerevisiae)
chr13_-_110438914 0.76 ENST00000375856.3
IRS2
insulin receptor substrate 2
chr2_+_159313452 0.76 ENST00000389757.3
ENST00000389759.3
PKP4
plakophilin 4
chr15_-_65067773 0.76 ENST00000300069.4
RBPMS2
RNA binding protein with multiple splicing 2
chr5_+_139028510 0.73 ENST00000502336.1
ENST00000520967.1
ENST00000511048.1
CXXC5
CXXC finger protein 5
chr5_-_172198190 0.73 ENST00000239223.3
DUSP1
dual specificity phosphatase 1
chr20_+_306221 0.73 ENST00000342665.2
SOX12
SRY (sex determining region Y)-box 12
chr5_-_107717058 0.72 ENST00000359660.5
FBXL17
F-box and leucine-rich repeat protein 17
chr9_+_71320596 0.71 ENST00000265382.3
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chrX_+_9754461 0.71 ENST00000380913.3
SHROOM2
shroom family member 2
chrX_+_130192318 0.70 ENST00000370922.1
ARHGAP36
Rho GTPase activating protein 36
chr17_+_81037473 0.68 ENST00000320095.7
METRNL
meteorin, glial cell differentiation regulator-like
chr6_+_17393888 0.68 ENST00000493172.1
ENST00000465994.1
CAP2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr5_+_175298573 0.67 ENST00000512824.1
CPLX2
complexin 2
chr20_-_35807970 0.66 ENST00000400440.2
ENST00000421643.1
MROH8
maestro heat-like repeat family member 8
chr22_-_36903101 0.65 ENST00000397224.4
FOXRED2
FAD-dependent oxidoreductase domain containing 2
chr6_+_17393839 0.64 ENST00000489374.1
ENST00000378990.2
CAP2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr11_-_63536113 0.63 ENST00000433688.1
ENST00000546282.2
C11orf95
RP11-466C23.4
chromosome 11 open reading frame 95
RP11-466C23.4
chr6_-_112575687 0.63 ENST00000521398.1
ENST00000424408.2
ENST00000243219.3
LAMA4
laminin, alpha 4
chr14_+_57046530 0.62 ENST00000536419.1
ENST00000538838.1
TMEM260
transmembrane protein 260
chr19_-_14201776 0.61 ENST00000269724.5
SAMD1
sterile alpha motif domain containing 1
chr1_+_211433275 0.59 ENST00000367005.4
RCOR3
REST corepressor 3
chr1_+_153700518 0.58 ENST00000318967.2
ENST00000456435.1
ENST00000435409.2
INTS3
integrator complex subunit 3
chrX_-_128788914 0.58 ENST00000429967.1
ENST00000307484.6
APLN
apelin
chr8_+_100025476 0.57 ENST00000355155.1
ENST00000357162.2
ENST00000358544.2
ENST00000395996.1
ENST00000441350.2
VPS13B
vacuolar protein sorting 13 homolog B (yeast)
chr1_-_236030216 0.56 ENST00000389794.3
ENST00000389793.2
LYST
lysosomal trafficking regulator
chr6_-_31865452 0.56 ENST00000375530.4
ENST00000375537.4
EHMT2
euchromatic histone-lysine N-methyltransferase 2
chrX_-_112084043 0.56 ENST00000304758.1
AMOT
angiomotin
chr14_+_57046500 0.56 ENST00000261556.6
TMEM260
transmembrane protein 260
chr1_-_171711177 0.54 ENST00000415773.1
ENST00000367740.2
VAMP4
vesicle-associated membrane protein 4
chr10_-_123687431 0.54 ENST00000423243.1
ATE1
arginyltransferase 1
chr4_+_145567173 0.54 ENST00000296575.3
HHIP
hedgehog interacting protein
chr1_+_211432593 0.53 ENST00000367006.4
RCOR3
REST corepressor 3
chr16_-_2246436 0.53 ENST00000343516.6
CASKIN1
CASK interacting protein 1
chr1_+_206138884 0.52 ENST00000341209.5
ENST00000607379.1
FAM72A
family with sequence similarity 72, member A
chr8_-_100025238 0.52 ENST00000521696.1
RP11-410L14.2
RP11-410L14.2
chr6_-_112575838 0.52 ENST00000455073.1
LAMA4
laminin, alpha 4
chr7_+_94139105 0.52 ENST00000297273.4
CASD1
CAS1 domain containing 1
chr19_-_2051223 0.51 ENST00000309340.7
ENST00000589534.1
ENST00000250896.3
ENST00000589509.1
MKNK2
MAP kinase interacting serine/threonine kinase 2
chr1_+_26146397 0.51 ENST00000374303.2
ENST00000533762.1
ENST00000529116.1
ENST00000474295.1
ENST00000488327.2
ENST00000472643.1
ENST00000526894.1
ENST00000524618.1
ENST00000374307.5
MTFR1L
mitochondrial fission regulator 1-like
chr2_+_48667898 0.50 ENST00000281394.4
ENST00000294952.8
PPP1R21
protein phosphatase 1, regulatory subunit 21
chr3_+_111578027 0.50 ENST00000431670.2
ENST00000412622.1
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr19_-_46272106 0.50 ENST00000560168.1
SIX5
SIX homeobox 5
chrX_-_114468605 0.48 ENST00000538422.1
ENST00000317135.8
LRCH2
leucine-rich repeats and calponin homology (CH) domain containing 2
chr17_-_65241281 0.48 ENST00000358691.5
ENST00000580168.1
HELZ
helicase with zinc finger
chr12_+_109535373 0.48 ENST00000242576.2
UNG
uracil-DNA glycosylase
chr1_-_46598371 0.47 ENST00000372006.1
ENST00000425892.1
ENST00000420542.1
ENST00000354242.4
ENST00000340332.6
PIK3R3
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr6_-_112575758 0.46 ENST00000431543.2
ENST00000453937.2
ENST00000368638.4
ENST00000389463.4
LAMA4
laminin, alpha 4
chr9_+_79792269 0.46 ENST00000376634.4
ENST00000376636.3
ENST00000360280.3
VPS13A
vacuolar protein sorting 13 homolog A (S. cerevisiae)
chrX_-_133931164 0.46 ENST00000370790.1
ENST00000298090.6
FAM122B
family with sequence similarity 122B
chr3_-_129612394 0.46 ENST00000505616.1
ENST00000426664.2
TMCC1
transmembrane and coiled-coil domain family 1
chr21_-_34100244 0.45 ENST00000382491.3
ENST00000357345.3
ENST00000429236.1
SYNJ1
synaptojanin 1
chr3_+_111578131 0.45 ENST00000498699.1
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr10_+_112404132 0.44 ENST00000369519.3
RBM20
RNA binding motif protein 20
chr8_+_42396936 0.44 ENST00000416469.2
SMIM19
small integral membrane protein 19
chr13_+_76210448 0.43 ENST00000377499.5
LMO7
LIM domain 7
chr1_+_26146674 0.43 ENST00000525713.1
ENST00000374301.3
MTFR1L
mitochondrial fission regulator 1-like
chr10_-_69835099 0.43 ENST00000373700.4
HERC4
HECT and RLD domain containing E3 ubiquitin protein ligase 4
chr11_-_18343669 0.42 ENST00000396253.3
ENST00000349215.3
ENST00000438420.2
HPS5
Hermansky-Pudlak syndrome 5
chr8_-_27469196 0.42 ENST00000546343.1
ENST00000560566.1
CLU
clusterin
chr19_-_45909585 0.42 ENST00000593226.1
ENST00000418234.2
PPP1R13L
protein phosphatase 1, regulatory subunit 13 like
chr16_+_2014993 0.42 ENST00000564014.1
SNHG9
small nucleolar RNA host gene 9 (non-protein coding)
chr1_+_180601139 0.42 ENST00000367590.4
ENST00000367589.3
XPR1
xenotropic and polytropic retrovirus receptor 1
chr2_-_105946491 0.42 ENST00000393359.2
TGFBRAP1
transforming growth factor, beta receptor associated protein 1
chr10_+_38299546 0.41 ENST00000374618.3
ENST00000432900.2
ENST00000458705.2
ENST00000469037.2
ZNF33A
zinc finger protein 33A
chr2_+_220306745 0.41 ENST00000431523.1
ENST00000396698.1
ENST00000396695.2
SPEG
SPEG complex locus
chr6_-_31864977 0.40 ENST00000395728.3
ENST00000375528.4
EHMT2
euchromatic histone-lysine N-methyltransferase 2
chr15_-_72490114 0.40 ENST00000309731.7
GRAMD2
GRAM domain containing 2
chr3_+_111578640 0.40 ENST00000393925.3
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr3_-_123168551 0.40 ENST00000462833.1
ADCY5
adenylate cyclase 5
chr13_-_76111945 0.40 ENST00000355801.4
ENST00000406936.3
COMMD6
COMM domain containing 6
chr4_+_145567297 0.39 ENST00000434550.2
HHIP
hedgehog interacting protein
chr3_+_170075436 0.39 ENST00000476188.1
ENST00000259119.4
ENST00000426052.2
SKIL
SKI-like oncogene
chr16_-_10674528 0.39 ENST00000359543.3
EMP2
epithelial membrane protein 2
chr2_-_201828356 0.38 ENST00000234296.2
ORC2
origin recognition complex, subunit 2
chr11_+_67159416 0.38 ENST00000307980.2
ENST00000544620.1
RAD9A
RAD9 homolog A (S. pombe)
chrX_+_47444613 0.38 ENST00000445623.1
TIMP1
TIMP metallopeptidase inhibitor 1
chr1_-_171711387 0.38 ENST00000236192.7
VAMP4
vesicle-associated membrane protein 4
chr17_+_62075703 0.38 ENST00000577953.1
ENST00000582540.1
ENST00000579184.1
ENST00000425164.3
ENST00000412177.1
ENST00000539996.1
ENST00000583891.1
ENST00000580752.1
C17orf72
chromosome 17 open reading frame 72
chr7_-_8302164 0.38 ENST00000447326.1
ENST00000406470.2
ICA1
islet cell autoantigen 1, 69kDa
chr6_+_43149903 0.37 ENST00000252050.4
ENST00000354495.3
ENST00000372647.2
CUL9
cullin 9
chr12_+_107168418 0.37 ENST00000392839.2
ENST00000548914.1
ENST00000355478.2
ENST00000552619.1
ENST00000549643.1
RIC8B
RIC8 guanine nucleotide exchange factor B
chr7_-_8301768 0.37 ENST00000265577.7
ICA1
islet cell autoantigen 1, 69kDa
chr6_-_79787902 0.37 ENST00000275034.4
PHIP
pleckstrin homology domain interacting protein
chr5_+_111496631 0.36 ENST00000508590.1
EPB41L4A-AS1
EPB41L4A antisense RNA 1
chr20_-_49253425 0.36 ENST00000045083.2
FAM65C
family with sequence similarity 65, member C
chr7_-_8301682 0.36 ENST00000396675.3
ENST00000430867.1
ICA1
islet cell autoantigen 1, 69kDa
chr3_-_47517302 0.36 ENST00000441517.2
ENST00000545718.1
SCAP
SREBF chaperone
chr5_+_111496554 0.36 ENST00000442823.2
EPB41L4A-AS1
EPB41L4A antisense RNA 1
chr5_+_121647386 0.36 ENST00000542191.1
ENST00000506272.1
ENST00000508681.1
ENST00000509154.2
SNCAIP
synuclein, alpha interacting protein
chr14_-_24804269 0.36 ENST00000310677.4
ENST00000554068.2
ENST00000559167.1
ENST00000561138.1
ADCY4
adenylate cyclase 4
chr3_-_125094093 0.35 ENST00000484491.1
ENST00000492394.1
ENST00000471196.1
ENST00000468369.1
ENST00000544464.1
ENST00000485866.1
ENST00000360647.4
ZNF148
zinc finger protein 148
chr8_+_42396712 0.35 ENST00000518574.1
ENST00000417410.2
ENST00000414154.2
SMIM19
small integral membrane protein 19
chrX_-_119763835 0.35 ENST00000371313.2
ENST00000304661.5
C1GALT1C1
C1GALT1-specific chaperone 1
chrX_+_130192216 0.35 ENST00000276211.5
ARHGAP36
Rho GTPase activating protein 36
chr2_-_43823093 0.35 ENST00000405006.4
THADA
thyroid adenoma associated
chr20_-_18038521 0.35 ENST00000278780.6
OVOL2
ovo-like zinc finger 2
chr16_-_90085824 0.34 ENST00000002501.6
DBNDD1
dysbindin (dystrobrevin binding protein 1) domain containing 1
chr10_-_123687497 0.34 ENST00000369040.3
ENST00000224652.6
ENST00000369043.3
ATE1
arginyltransferase 1
chr4_+_150999418 0.34 ENST00000296550.7
DCLK2
doublecortin-like kinase 2
chr12_+_27677085 0.34 ENST00000545334.1
ENST00000540114.1
ENST00000537927.1
ENST00000318304.8
ENST00000535047.1
ENST00000542629.1
ENST00000228425.6
PPFIBP1
PTPRF interacting protein, binding protein 1 (liprin beta 1)
chr17_-_42277203 0.34 ENST00000587097.1
ATXN7L3
ataxin 7-like 3
chr1_+_95699704 0.33 ENST00000370202.4
RWDD3
RWD domain containing 3
chr17_+_45608614 0.33 ENST00000544660.1
NPEPPS
aminopeptidase puromycin sensitive
chr4_-_151936416 0.33 ENST00000510413.1
ENST00000507224.1
LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chr20_-_46415341 0.32 ENST00000484875.1
ENST00000361612.4
SULF2
sulfatase 2
chr20_-_46415297 0.32 ENST00000467815.1
ENST00000359930.4
SULF2
sulfatase 2
chr2_+_32390925 0.32 ENST00000440718.1
ENST00000379343.2
ENST00000282587.5
ENST00000435660.1
ENST00000538303.1
ENST00000357055.3
ENST00000406369.1
SLC30A6
solute carrier family 30 (zinc transporter), member 6
chr21_-_34100341 0.31 ENST00000382499.2
ENST00000433931.2
SYNJ1
synaptojanin 1
chr10_+_75532028 0.31 ENST00000372841.3
ENST00000394790.1
FUT11
fucosyltransferase 11 (alpha (1,3) fucosyltransferase)
chr15_+_91446157 0.31 ENST00000559717.1
MAN2A2
mannosidase, alpha, class 2A, member 2
chr7_-_8301869 0.31 ENST00000402384.3
ICA1
islet cell autoantigen 1, 69kDa
chr2_+_204193149 0.31 ENST00000422511.2
ABI2
abl-interactor 2
chr2_+_234545148 0.31 ENST00000373445.1
UGT1A10
UDP glucuronosyltransferase 1 family, polypeptide A10
chr11_+_57508825 0.31 ENST00000534355.1
C11orf31
chromosome 11 open reading frame 31
chr11_+_64794875 0.30 ENST00000377244.3
ENST00000534637.1
ENST00000524831.1
SNX15
sorting nexin 15
chr1_-_87379785 0.30 ENST00000401030.3
ENST00000370554.1
SEP15
Homo sapiens 15 kDa selenoprotein (SEP15), transcript variant 2, mRNA.
chr16_+_15528332 0.29 ENST00000566490.1
C16orf45
chromosome 16 open reading frame 45
chr12_+_49212514 0.29 ENST00000301050.2
ENST00000548279.1
ENST00000547230.1
CACNB3
calcium channel, voltage-dependent, beta 3 subunit
chr22_-_29663954 0.29 ENST00000216085.7
RHBDD3
rhomboid domain containing 3
chr5_+_57878859 0.28 ENST00000282878.4
RAB3C
RAB3C, member RAS oncogene family
chr2_-_183903133 0.28 ENST00000361354.4
NCKAP1
NCK-associated protein 1
chr17_-_73267214 0.28 ENST00000580717.1
ENST00000577542.1
ENST00000579612.1
ENST00000245551.5
MIF4GD
MIF4G domain containing
chr10_-_69834973 0.28 ENST00000395187.2
HERC4
HECT and RLD domain containing E3 ubiquitin protein ligase 4
chr1_+_222817629 0.28 ENST00000340535.7
MIA3
melanoma inhibitory activity family, member 3
chr5_+_121647764 0.28 ENST00000261368.8
ENST00000379533.2
ENST00000379536.2
ENST00000379538.3
SNCAIP
synuclein, alpha interacting protein
chr8_+_125486939 0.27 ENST00000303545.3
RNF139
ring finger protein 139
chr10_-_17659357 0.27 ENST00000326961.6
ENST00000361271.3
PTPLA
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr9_+_96338647 0.27 ENST00000359246.4
PHF2
PHD finger protein 2
chr5_+_159343688 0.26 ENST00000306675.3
ADRA1B
adrenoceptor alpha 1B
chr4_+_159593418 0.26 ENST00000507475.1
ENST00000307738.5
ETFDH
electron-transferring-flavoprotein dehydrogenase
chr12_+_107168342 0.25 ENST00000392837.4
RIC8B
RIC8 guanine nucleotide exchange factor B
chr9_+_131451480 0.25 ENST00000322030.8
SET
SET nuclear oncogene
chr2_+_54198210 0.25 ENST00000607452.1
ENST00000422521.2
ACYP2
acylphosphatase 2, muscle type
chr2_+_204193129 0.25 ENST00000417864.1
ABI2
abl-interactor 2
chr5_-_137368708 0.25 ENST00000033079.3
FAM13B
family with sequence similarity 13, member B
chr2_+_204192942 0.25 ENST00000295851.5
ENST00000261017.5
ABI2
abl-interactor 2
chr17_-_73267281 0.25 ENST00000578305.1
ENST00000325102.8
MIF4GD
MIF4G domain containing
chr17_-_73267304 0.24 ENST00000579297.1
ENST00000580571.1
MIF4GD
MIF4G domain containing
chr5_-_42811986 0.24 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
SEPP1
selenoprotein P, plasma, 1
chr22_-_38794490 0.24 ENST00000400206.2
CSNK1E
casein kinase 1, epsilon
chr1_-_94312706 0.24 ENST00000370244.1
BCAR3
breast cancer anti-estrogen resistance 3
chr1_-_46598284 0.24 ENST00000423209.1
ENST00000262741.5
PIK3R3
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr7_+_142960505 0.23 ENST00000409500.3
ENST00000443571.2
ENST00000358406.5
ENST00000479303.1
GSTK1
glutathione S-transferase kappa 1
chr5_+_175298674 0.23 ENST00000514150.1
CPLX2
complexin 2
chr1_-_156390128 0.23 ENST00000368242.3
C1orf61
chromosome 1 open reading frame 61
chr18_+_56338750 0.23 ENST00000345724.3
MALT1
mucosa associated lymphoid tissue lymphoma translocation gene 1
chr7_+_26438187 0.23 ENST00000439120.1
ENST00000430548.1
ENST00000421862.1
ENST00000449537.1
ENST00000420774.1
ENST00000418758.2
AC004540.5
AC004540.5
chr20_+_3026591 0.23 ENST00000380325.3
MRPS26
mitochondrial ribosomal protein S26
chr14_+_57857262 0.22 ENST00000555166.1
ENST00000556492.1
ENST00000554703.1
NAA30
N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr2_+_234545092 0.22 ENST00000344644.5
UGT1A10
UDP glucuronosyltransferase 1 family, polypeptide A10
chr17_-_28618948 0.22 ENST00000261714.6
BLMH
bleomycin hydrolase
chr17_-_36413133 0.22 ENST00000523089.1
ENST00000312412.4
ENST00000520237.1
RP11-1407O15.2
TBC1 domain family member 3
chr11_+_111957497 0.21 ENST00000375549.3
ENST00000528182.1
ENST00000528048.1
ENST00000528021.1
ENST00000526592.1
ENST00000525291.1
SDHD
succinate dehydrogenase complex, subunit D, integral membrane protein
chr2_-_43823119 0.21 ENST00000403856.1
ENST00000404790.1
ENST00000405975.2
ENST00000415080.2
THADA
thyroid adenoma associated
chr14_+_96968707 0.21 ENST00000216277.8
ENST00000557320.1
ENST00000557471.1
PAPOLA
poly(A) polymerase alpha
chr1_+_52608046 0.21 ENST00000357206.2
ENST00000287727.3
ZFYVE9
zinc finger, FYVE domain containing 9
chr19_+_56116771 0.21 ENST00000568956.1
ZNF865
zinc finger protein 865
chr19_+_3572925 0.21 ENST00000333651.6
ENST00000417382.1
ENST00000453933.1
ENST00000262949.7
HMG20B
high mobility group 20B
chr2_-_38830160 0.20 ENST00000409636.1
ENST00000608859.1
ENST00000358367.4
HNRNPLL
heterogeneous nuclear ribonucleoprotein L-like
chr7_+_75677354 0.20 ENST00000461263.2
ENST00000315758.5
ENST00000443006.1
MDH2
malate dehydrogenase 2, NAD (mitochondrial)
chr11_-_117186946 0.20 ENST00000313005.6
ENST00000528053.1
BACE1
beta-site APP-cleaving enzyme 1

Network of associatons between targets according to the STRING database.

First level regulatory network of NR0B1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.1 GO:0051622 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.5 3.4 GO:0007386 compartment pattern specification(GO:0007386)
0.5 3.9 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.5 1.8 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.4 1.1 GO:0010645 pulmonary valve formation(GO:0003193) regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652) foramen ovale closure(GO:0035922) regulation of bundle of His cell action potential(GO:0098905)
0.4 1.8 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.3 1.7 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.3 1.9 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.3 0.8 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.2 0.9 GO:0016598 protein arginylation(GO:0016598)
0.2 0.6 GO:0043396 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) regulation of G-protein coupled receptor internalization(GO:1904020)
0.2 0.8 GO:1904978 regulation of endosome organization(GO:1904978)
0.2 0.6 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.2 0.5 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.2 0.6 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.6 GO:1901895 negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.1 0.4 GO:0070631 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.1 0.8 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.1 0.8 GO:0010748 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.1 1.1 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.8 GO:0040038 polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649)
0.1 0.8 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1 0.3 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.1 1.1 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.4 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 0.3 GO:0061188 negative regulation of chromatin silencing at rDNA(GO:0061188)
0.1 2.1 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 1.1 GO:0003149 membranous septum morphogenesis(GO:0003149)
0.1 1.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 1.8 GO:0016180 snRNA processing(GO:0016180)
0.1 0.4 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 0.3 GO:1901091 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.1 1.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 0.7 GO:0051552 flavone metabolic process(GO:0051552)
0.1 0.2 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 0.3 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.1 0.2 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.1 0.2 GO:0033386 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.1 0.4 GO:0043418 homocysteine catabolic process(GO:0043418)
0.1 0.3 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.1 0.3 GO:0060214 endocardium formation(GO:0060214)
0.1 0.2 GO:1903823 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.1 0.7 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.1 0.2 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.1 0.2 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.1 0.9 GO:0090161 Golgi ribbon formation(GO:0090161)
0.1 0.4 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.2 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.7 GO:0045176 apical protein localization(GO:0045176)
0.0 1.3 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.2 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
0.0 0.2 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.0 0.7 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.8 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.2 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.4 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.2 GO:0002086 diaphragm contraction(GO:0002086)
0.0 0.3 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 1.0 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.4 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 1.4 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.4 GO:0070836 caveola assembly(GO:0070836)
0.0 0.3 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.4 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.3 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.0 0.3 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.4 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.8 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.6 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 1.7 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.3 GO:0021859 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0 0.1 GO:1903567 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.0 0.5 GO:0045008 depyrimidination(GO:0045008)
0.0 0.3 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0071529 cementum mineralization(GO:0071529)
0.0 0.1 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.3 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.0 0.7 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.1 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.0 0.7 GO:0060441 epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.0 0.5 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.1 GO:1900114 pathogenesis(GO:0009405) positive regulation of histone H3-K9 trimethylation(GO:1900114)
0.0 0.1 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.0 2.7 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 1.3 GO:0048663 neuron fate commitment(GO:0048663)
0.0 0.2 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.5 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.8 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.2 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.9 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.7 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.0 0.2 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.2 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0 0.5 GO:0042417 dopamine metabolic process(GO:0042417)
0.0 0.1 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.2 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.1 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.4 GO:0036344 platelet morphogenesis(GO:0036344)
0.0 0.2 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.3 GO:0036065 fucosylation(GO:0036065)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 3.4 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 0.4 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 1.8 GO:0032039 integrator complex(GO:0032039)
0.1 0.4 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.1 0.4 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.1 2.0 GO:0045180 basal cortex(GO:0045180)
0.1 0.9 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1 0.8 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 3.9 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 3.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.4 GO:0033263 CORVET complex(GO:0033263)
0.1 0.3 GO:0097224 sperm connecting piece(GO:0097224)
0.1 1.1 GO:0031209 SCAR complex(GO:0031209)
0.1 0.2 GO:0043291 RAVE complex(GO:0043291)
0.1 0.2 GO:0031417 NatC complex(GO:0031417)
0.1 0.2 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 1.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.1 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0032449 CBM complex(GO:0032449)
0.0 0.4 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.2 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 1.6 GO:0005605 basal lamina(GO:0005605)
0.0 0.9 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.3 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.4 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.8 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 0.8 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.5 GO:0031045 dense core granule(GO:0031045)
0.0 1.5 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.2 GO:0001740 Barr body(GO:0001740)
0.0 2.6 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124)
0.0 1.0 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.3 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.2 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.8 GO:0051233 spindle midzone(GO:0051233)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 1.9 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 1.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.9 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.1 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 2.1 GO:0001650 fibrillar center(GO:0001650)
0.0 0.6 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.8 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.6 3.1 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.6 3.9 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.3 2.5 GO:0048039 ubiquinone binding(GO:0048039)
0.3 1.1 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.2 0.7 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2 0.9 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.2 1.8 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.2 0.9 GO:0004057 arginyltransferase activity(GO:0004057)
0.2 0.8 GO:0043398 HLH domain binding(GO:0043398) calcium-induced calcium release activity(GO:0048763)
0.2 0.8 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1 1.0 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 0.9 GO:0097108 hedgehog family protein binding(GO:0097108)
0.1 0.6 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.4 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 1.7 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.6 GO:0043532 angiostatin binding(GO:0043532)
0.1 0.3 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.2 GO:0004794 L-threonine ammonia-lyase activity(GO:0004794)
0.1 0.2 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.1 0.2 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.1 0.4 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 0.4 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 0.5 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.1 0.3 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.1 0.2 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 1.1 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.2 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.3 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.2 GO:0043813 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.0 0.7 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 1.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.5 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.3 GO:0097001 ceramide binding(GO:0097001)
0.0 1.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 2.2 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.2 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 1.8 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.2 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.8 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.0 0.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.2 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.2 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 1.0 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.3 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.3 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 1.1 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.4 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.3 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.9 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.4 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 1.0 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.2 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 1.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.2 GO:0015266 protein channel activity(GO:0015266)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.2 GO:0010181 FMN binding(GO:0010181)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.3 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 3.7 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.8 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 2.0 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.7 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.8 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.8 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.2 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.6 PID TGFBR PATHWAY TGF-beta receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 1.9 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 0.8 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 1.1 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 1.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.8 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.8 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 3.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.4 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 1.0 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.4 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.2 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.4 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.0 1.4 REACTOME DNA REPAIR Genes involved in DNA Repair