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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for NR1H2

Z-value: 0.47

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Transcription factors associated with NR1H2

Gene Symbol Gene ID Gene Info
NR1H2
ENSG00000131408.9 nuclear receptor subfamily 1 group H member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR1H2hg19_v2_chr19_+_50832943_508329510.174.2e-01Click!

Activity profile of NR1H2 motif

Sorted Z-values of NR1H2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr21_+_43619796 1.78 ENST00000398457.2
ABCG1
ATP-binding cassette, sub-family G (WHITE), member 1
chr1_+_169075554 1.38 ENST00000367815.4
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr17_+_77019030 1.28 ENST00000580454.1
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr17_+_77018896 1.25 ENST00000578229.1
C1QTNF1
C1q and tumor necrosis factor related protein 1
chrX_+_1455478 1.18 ENST00000331035.4
IL3RA
interleukin 3 receptor, alpha (low affinity)
chr4_-_681114 1.09 ENST00000503156.1
MFSD7
major facilitator superfamily domain containing 7
chr7_-_22259845 1.05 ENST00000420196.1
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr2_+_223725652 1.04 ENST00000357430.3
ENST00000392066.3
ACSL3
acyl-CoA synthetase long-chain family member 3
chr5_+_35856951 0.90 ENST00000303115.3
ENST00000343305.4
ENST00000506850.1
ENST00000511982.1
IL7R
interleukin 7 receptor
chr20_+_31805131 0.86 ENST00000375454.3
ENST00000375452.3
BPIFA3
BPI fold containing family A, member 3
chr19_-_49658387 0.70 ENST00000595625.1
HRC
histidine rich calcium binding protein
chr9_-_139293249 0.66 ENST00000298532.2
SNAPC4
small nuclear RNA activating complex, polypeptide 4, 190kDa
chr1_-_237167718 0.66 ENST00000464121.2
MT1HL1
metallothionein 1H-like 1
chr5_-_138862326 0.63 ENST00000330794.4
TMEM173
transmembrane protein 173
chr18_+_21693306 0.60 ENST00000540918.2
TTC39C
tetratricopeptide repeat domain 39C
chr2_+_73441350 0.50 ENST00000389501.4
SMYD5
SMYD family member 5
chr19_+_33071974 0.48 ENST00000590247.2
ENST00000419343.3
ENST00000592786.1
ENST00000379316.3
PDCD5
programmed cell death 5
chr16_+_4674814 0.47 ENST00000415496.1
ENST00000587747.1
ENST00000399577.5
ENST00000588994.1
ENST00000586183.1
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr7_-_76247617 0.46 ENST00000441393.1
POMZP3
POM121 and ZP3 fusion
chr11_-_82611448 0.43 ENST00000393399.2
ENST00000313010.3
PRCP
prolylcarboxypeptidase (angiotensinase C)
chr1_+_23037323 0.42 ENST00000544305.1
ENST00000374630.3
ENST00000400191.3
ENST00000374632.3
EPHB2
EPH receptor B2
chr17_-_49198216 0.41 ENST00000262013.7
ENST00000357122.4
SPAG9
sperm associated antigen 9
chr16_+_4674787 0.41 ENST00000262370.7
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr1_-_161207986 0.40 ENST00000506209.1
ENST00000367980.2
NR1I3
nuclear receptor subfamily 1, group I, member 3
chr15_+_75498739 0.39 ENST00000565074.1
C15orf39
chromosome 15 open reading frame 39
chr8_-_48651648 0.39 ENST00000408965.3
CEBPD
CCAAT/enhancer binding protein (C/EBP), delta
chr17_-_8151353 0.39 ENST00000315684.8
CTC1
CTS telomere maintenance complex component 1
chr22_-_24096630 0.38 ENST00000248948.3
VPREB3
pre-B lymphocyte 3
chr1_-_161207953 0.38 ENST00000367982.4
NR1I3
nuclear receptor subfamily 1, group I, member 3
chr1_-_161208013 0.38 ENST00000515452.1
ENST00000367983.4
NR1I3
nuclear receptor subfamily 1, group I, member 3
chr20_-_5485166 0.37 ENST00000589201.1
ENST00000379053.4
LINC00654
long intergenic non-protein coding RNA 654
chr7_+_153584166 0.36 ENST00000404039.1
DPP6
dipeptidyl-peptidase 6
chr17_+_32683456 0.33 ENST00000225844.2
CCL13
chemokine (C-C motif) ligand 13
chr12_-_322504 0.31 ENST00000424061.2
SLC6A12
solute carrier family 6 (neurotransmitter transporter), member 12
chr2_+_168043793 0.31 ENST00000409273.1
ENST00000409605.1
XIRP2
xin actin-binding repeat containing 2
chr17_-_17480779 0.31 ENST00000395782.1
PEMT
phosphatidylethanolamine N-methyltransferase
chrX_+_23801280 0.30 ENST00000379251.3
ENST00000379253.3
ENST00000379254.1
ENST00000379270.4
SAT1
spermidine/spermine N1-acetyltransferase 1
chr2_+_27255806 0.30 ENST00000238788.9
ENST00000404032.3
TMEM214
transmembrane protein 214
chr12_-_322821 0.30 ENST00000359674.4
SLC6A12
solute carrier family 6 (neurotransmitter transporter), member 12
chr9_-_130829588 0.29 ENST00000373078.4
NAIF1
nuclear apoptosis inducing factor 1
chr3_-_127309879 0.28 ENST00000489960.1
ENST00000490290.1
TPRA1
transmembrane protein, adipocyte asscociated 1
chr10_-_70287172 0.27 ENST00000539557.1
SLC25A16
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16
chr22_-_24096562 0.27 ENST00000398465.3
VPREB3
pre-B lymphocyte 3
chr3_-_127309550 0.27 ENST00000296210.7
ENST00000355552.3
TPRA1
transmembrane protein, adipocyte asscociated 1
chr15_-_89010607 0.26 ENST00000312475.4
MRPL46
mitochondrial ribosomal protein L46
chr11_-_62420757 0.26 ENST00000330574.2
INTS5
integrator complex subunit 5
chr1_+_87595542 0.25 ENST00000461990.1
RP5-1052I5.1
long intergenic non-protein coding RNA 1140
chr20_+_33292068 0.25 ENST00000374810.3
ENST00000374809.2
ENST00000451665.1
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr17_-_19648916 0.25 ENST00000444455.1
ENST00000439102.2
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr16_+_56969284 0.25 ENST00000568358.1
HERPUD1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr19_+_34287174 0.25 ENST00000587559.1
ENST00000588637.1
KCTD15
potassium channel tetramerization domain containing 15
chr16_-_4465886 0.25 ENST00000539968.1
CORO7
coronin 7
chr3_-_195310802 0.25 ENST00000421243.1
ENST00000453131.1
APOD
apolipoprotein D
chr3_+_9691117 0.23 ENST00000353332.5
ENST00000420925.1
ENST00000296003.4
ENST00000351233.5
MTMR14
myotubularin related protein 14
chr12_-_9913489 0.23 ENST00000228434.3
ENST00000536709.1
CD69
CD69 molecule
chr1_-_9714644 0.23 ENST00000377320.3
C1orf200
chromosome 1 open reading frame 200
chr15_+_81589254 0.23 ENST00000394652.2
IL16
interleukin 16
chr7_+_142031986 0.22 ENST00000547918.2
TRBV7-1
T cell receptor beta variable 7-1 (non-functional)
chr4_-_2965052 0.22 ENST00000398071.4
ENST00000502735.1
ENST00000314262.6
ENST00000416614.2
NOP14
NOP14 nucleolar protein
chr16_+_30710462 0.21 ENST00000262518.4
ENST00000395059.2
ENST00000344771.4
SRCAP
Snf2-related CREBBP activator protein
chr11_+_1074870 0.21 ENST00000441003.2
ENST00000359061.5
MUC2
mucin 2, oligomeric mucus/gel-forming
chr1_+_10459111 0.21 ENST00000541529.1
ENST00000270776.8
ENST00000483936.1
ENST00000538557.1
PGD
phosphogluconate dehydrogenase
chr19_-_46285646 0.21 ENST00000458663.2
DMPK
dystrophia myotonica-protein kinase
chr8_+_132916318 0.21 ENST00000254624.5
ENST00000522709.1
EFR3A
EFR3 homolog A (S. cerevisiae)
chr1_+_156338993 0.20 ENST00000368249.1
ENST00000368246.2
ENST00000537040.1
ENST00000400992.2
ENST00000255013.3
ENST00000451864.2
RHBG
Rh family, B glycoprotein (gene/pseudogene)
chr4_+_57371509 0.20 ENST00000360096.2
ARL9
ADP-ribosylation factor-like 9
chr19_+_41092680 0.19 ENST00000594298.1
ENST00000597396.1
SHKBP1
SH3KBP1 binding protein 1
chr20_+_43343886 0.19 ENST00000190983.4
WISP2
WNT1 inducible signaling pathway protein 2
chr17_-_42580738 0.19 ENST00000585614.1
ENST00000591680.1
ENST00000434000.1
ENST00000588554.1
ENST00000592154.1
GPATCH8
G patch domain containing 8
chr11_+_77774897 0.19 ENST00000281030.2
THRSP
thyroid hormone responsive
chr15_-_102285007 0.19 ENST00000560292.2
RP11-89K11.1
Uncharacterized protein
chr12_-_56694142 0.18 ENST00000550655.1
ENST00000548567.1
ENST00000551430.2
ENST00000351328.3
CS
citrate synthase
chr12_+_56511943 0.18 ENST00000257940.2
ENST00000552345.1
ENST00000551880.1
ENST00000546903.1
ENST00000551790.1
ZC3H10
ESYT1
zinc finger CCCH-type containing 10
extended synaptotagmin-like protein 1
chr2_-_165697920 0.18 ENST00000342193.4
ENST00000375458.2
COBLL1
cordon-bleu WH2 repeat protein-like 1
chr6_+_30687978 0.18 ENST00000327892.8
ENST00000435534.1
TUBB
tubulin, beta class I
chr1_-_11007927 0.18 ENST00000468348.1
C1orf127
chromosome 1 open reading frame 127
chr11_-_62521614 0.18 ENST00000527994.1
ENST00000394807.3
ZBTB3
zinc finger and BTB domain containing 3
chr1_+_10290822 0.18 ENST00000377083.1
KIF1B
kinesin family member 1B
chr17_-_8198636 0.18 ENST00000577745.1
ENST00000579192.1
ENST00000396278.1
SLC25A35
solute carrier family 25, member 35
chr21_-_46340770 0.18 ENST00000397854.3
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr11_+_64692143 0.18 ENST00000164133.2
ENST00000532850.1
PPP2R5B
protein phosphatase 2, regulatory subunit B', beta
chr19_+_52264104 0.18 ENST00000340023.6
FPR2
formyl peptide receptor 2
chr22_+_18260077 0.18 ENST00000600723.1
LINC00528
long intergenic non-protein coding RNA 528
chr20_+_43343517 0.17 ENST00000372865.4
WISP2
WNT1 inducible signaling pathway protein 2
chr7_-_56160625 0.17 ENST00000446428.1
ENST00000432123.1
ENST00000452681.2
ENST00000537360.1
PHKG1
phosphorylase kinase, gamma 1 (muscle)
chr20_+_5987890 0.17 ENST00000378868.4
CRLS1
cardiolipin synthase 1
chr5_+_43120985 0.17 ENST00000515326.1
ZNF131
zinc finger protein 131
chr1_+_100818156 0.16 ENST00000336454.3
CDC14A
cell division cycle 14A
chr16_+_577697 0.16 ENST00000562370.1
ENST00000568988.1
ENST00000219611.2
CAPN15
calpain 15
chr22_+_30792846 0.16 ENST00000312932.9
ENST00000428195.1
SEC14L2
SEC14-like 2 (S. cerevisiae)
chr3_-_49893958 0.16 ENST00000482243.1
ENST00000331456.2
ENST00000469027.1
TRAIP
TRAF interacting protein
chr3_+_39371255 0.16 ENST00000414803.1
ENST00000545843.1
CCR8
chemokine (C-C motif) receptor 8
chr16_+_29467780 0.16 ENST00000395400.3
SULT1A4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
chrX_+_30248553 0.15 ENST00000361644.2
MAGEB3
melanoma antigen family B, 3
chr3_+_39371191 0.15 ENST00000326306.4
CCR8
chemokine (C-C motif) receptor 8
chr11_-_35440796 0.14 ENST00000278379.3
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr19_+_3224700 0.14 ENST00000292672.2
ENST00000541430.2
CELF5
CUGBP, Elav-like family member 5
chr1_-_67142710 0.14 ENST00000502413.2
AL139147.1
Uncharacterized protein
chr2_+_145425573 0.14 ENST00000600064.1
ENST00000597670.1
ENST00000414256.1
ENST00000599187.1
ENST00000451774.1
ENST00000599072.1
ENST00000596589.1
ENST00000597893.1
TEX41
testis expressed 41 (non-protein coding)
chr7_-_56160666 0.14 ENST00000297373.2
PHKG1
phosphorylase kinase, gamma 1 (muscle)
chr14_-_73925225 0.13 ENST00000356296.4
ENST00000355058.3
ENST00000359560.3
ENST00000557597.1
ENST00000554394.1
ENST00000555238.1
ENST00000535282.1
ENST00000555987.1
ENST00000555394.1
ENST00000554546.1
NUMB
numb homolog (Drosophila)
chr4_-_80247162 0.13 ENST00000286794.4
NAA11
N(alpha)-acetyltransferase 11, NatA catalytic subunit
chr4_-_83483395 0.13 ENST00000515780.2
TMEM150C
transmembrane protein 150C
chr5_-_58652788 0.13 ENST00000405755.2
PDE4D
phosphodiesterase 4D, cAMP-specific
chr11_+_32851487 0.13 ENST00000257836.3
PRRG4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr4_+_183164574 0.13 ENST00000511685.1
TENM3
teneurin transmembrane protein 3
chr20_+_35918035 0.13 ENST00000373606.3
ENST00000397156.3
ENST00000397150.1
ENST00000397152.3
MANBAL
mannosidase, beta A, lysosomal-like
chr1_+_100818009 0.12 ENST00000370125.2
ENST00000361544.6
ENST00000370124.3
CDC14A
cell division cycle 14A
chr1_+_87595497 0.12 ENST00000471417.1
RP5-1052I5.1
long intergenic non-protein coding RNA 1140
chr19_-_7968427 0.12 ENST00000539278.1
AC010336.1
Uncharacterized protein
chr17_-_26695013 0.12 ENST00000555059.2
CTB-96E2.2
Homeobox protein SEBOX
chr22_-_26875345 0.12 ENST00000398141.1
HPS4
Hermansky-Pudlak syndrome 4
chr3_+_46283863 0.11 ENST00000545097.1
ENST00000541018.1
CCR3
chemokine (C-C motif) receptor 3
chr1_+_169337172 0.11 ENST00000367807.3
ENST00000367808.3
ENST00000329281.2
ENST00000420531.1
BLZF1
basic leucine zipper nuclear factor 1
chr4_-_142134031 0.11 ENST00000420921.2
RNF150
ring finger protein 150
chr17_-_26694979 0.11 ENST00000438614.1
VTN
vitronectin
chr11_-_35441524 0.11 ENST00000395750.1
ENST00000449068.1
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr7_+_45067265 0.11 ENST00000474617.1
CCM2
cerebral cavernous malformation 2
chr8_-_61193947 0.11 ENST00000317995.4
CA8
carbonic anhydrase VIII
chr4_-_39034542 0.11 ENST00000344606.6
TMEM156
transmembrane protein 156
chr1_+_36335351 0.11 ENST00000373206.1
AGO1
argonaute RISC catalytic component 1
chr2_+_207630081 0.10 ENST00000236980.6
ENST00000418289.1
ENST00000402774.3
ENST00000403094.3
FASTKD2
FAST kinase domains 2
chr16_+_88704978 0.10 ENST00000244241.4
IL17C
interleukin 17C
chr9_+_95736758 0.10 ENST00000337352.6
FGD3
FYVE, RhoGEF and PH domain containing 3
chr15_-_83837983 0.10 ENST00000562702.1
HDGFRP3
Hepatoma-derived growth factor-related protein 3
chr10_+_1095416 0.09 ENST00000358220.1
WDR37
WD repeat domain 37
chr1_+_87458692 0.09 ENST00000370548.2
ENST00000356813.4
RP5-1052I5.2
HS2ST1
Heparan sulfate 2-O-sulfotransferase 1
heparan sulfate 2-O-sulfotransferase 1
chr6_-_31763721 0.09 ENST00000375663.3
VARS
valyl-tRNA synthetase
chr9_-_86955657 0.09 ENST00000537648.1
SLC28A3
solute carrier family 28 (concentrative nucleoside transporter), member 3
chr19_-_22193731 0.09 ENST00000601773.1
ENST00000397126.4
ENST00000601993.1
ENST00000599916.1
ZNF208
zinc finger protein 208
chr9_+_95726243 0.09 ENST00000416701.2
FGD3
FYVE, RhoGEF and PH domain containing 3
chr6_-_34639733 0.09 ENST00000374021.1
C6orf106
chromosome 6 open reading frame 106
chr14_-_59950724 0.09 ENST00000481608.1
L3HYPDH
L-3-hydroxyproline dehydratase (trans-)
chr21_-_37432540 0.09 ENST00000443703.1
ENST00000399207.1
ENST00000399215.1
ENST00000442559.1
ENST00000399205.1
ENST00000429161.1
ENST00000424303.1
ENST00000399208.2
SETD4
SET domain containing 4
chr10_+_126490354 0.09 ENST00000298492.5
FAM175B
family with sequence similarity 175, member B
chr2_+_101179152 0.09 ENST00000264254.6
PDCL3
phosducin-like 3
chr8_+_145218673 0.08 ENST00000326134.5
MROH1
maestro heat-like repeat family member 1
chr17_+_7184986 0.07 ENST00000317370.8
ENST00000571308.1
SLC2A4
solute carrier family 2 (facilitated glucose transporter), member 4
chr17_-_76975925 0.07 ENST00000591274.1
ENST00000589906.1
ENST00000591778.1
ENST00000589775.2
ENST00000585407.1
ENST00000262776.3
LGALS3BP
lectin, galactoside-binding, soluble, 3 binding protein
chr7_-_73153122 0.07 ENST00000458339.1
ABHD11
abhydrolase domain containing 11
chr19_-_46296011 0.07 ENST00000377735.3
ENST00000270223.6
DMWD
dystrophia myotonica, WD repeat containing
chr8_-_145652336 0.07 ENST00000529182.1
ENST00000526054.1
VPS28
vacuolar protein sorting 28 homolog (S. cerevisiae)
chr2_-_128615681 0.07 ENST00000409955.1
ENST00000272645.4
POLR2D
polymerase (RNA) II (DNA directed) polypeptide D
chrX_-_46759138 0.07 ENST00000377879.3
CXorf31
chromosome X open reading frame 31
chr9_+_34179003 0.07 ENST00000545103.1
ENST00000543944.1
ENST00000536252.1
ENST00000540348.1
ENST00000297661.4
ENST00000379186.4
UBAP1
ubiquitin associated protein 1
chr2_-_32390801 0.06 ENST00000608489.1
RP11-563N4.1
RP11-563N4.1
chr5_-_133968529 0.06 ENST00000402673.2
SAR1B
SAR1 homolog B (S. cerevisiae)
chr11_-_35441597 0.06 ENST00000395753.1
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr15_+_89010923 0.06 ENST00000353598.6
MRPS11
mitochondrial ribosomal protein S11
chr11_+_61159832 0.06 ENST00000334888.5
ENST00000398979.3
TMEM216
transmembrane protein 216
chr4_-_71705027 0.06 ENST00000545193.1
GRSF1
G-rich RNA sequence binding factor 1
chr14_-_102976135 0.06 ENST00000560748.1
ANKRD9
ankyrin repeat domain 9
chr14_+_23790655 0.05 ENST00000397276.2
PABPN1
poly(A) binding protein, nuclear 1
chr1_-_13115578 0.05 ENST00000414205.2
PRAMEF6
PRAME family member 6
chr22_+_19118321 0.05 ENST00000399635.2
TSSK2
testis-specific serine kinase 2
chr2_+_228029281 0.05 ENST00000396578.3
COL4A3
collagen, type IV, alpha 3 (Goodpasture antigen)
chr19_+_33622996 0.05 ENST00000592765.1
ENST00000361680.2
ENST00000355868.3
WDR88
WD repeat domain 88
chr3_+_139062838 0.05 ENST00000310776.4
ENST00000465056.1
ENST00000465373.1
MRPS22
mitochondrial ribosomal protein S22
chr4_-_71705060 0.05 ENST00000514161.1
GRSF1
G-rich RNA sequence binding factor 1
chr10_-_28623368 0.05 ENST00000441595.2
MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr2_+_145425534 0.05 ENST00000432608.1
ENST00000597655.1
ENST00000598659.1
ENST00000600679.1
ENST00000601277.1
ENST00000451027.1
ENST00000445791.1
ENST00000596540.1
ENST00000596230.1
ENST00000594471.1
ENST00000598248.1
ENST00000597469.1
ENST00000431734.1
ENST00000595686.1
TEX41
testis expressed 41 (non-protein coding)
chr17_-_15370915 0.04 ENST00000312177.6
CDRT4
CMT1A duplicated region transcript 4
chr19_+_58545434 0.04 ENST00000282326.1
ENST00000601162.1
ZSCAN1
zinc finger and SCAN domain containing 1
chr5_+_76145920 0.04 ENST00000317593.4
S100Z
S100 calcium binding protein Z
chr17_+_60457914 0.04 ENST00000305286.3
ENST00000520404.1
ENST00000518576.1
EFCAB3
EF-hand calcium binding domain 3
chr22_-_36031181 0.04 ENST00000594060.1
AL049747.1
AL049747.1
chr20_+_30028322 0.04 ENST00000376309.3
DEFB123
defensin, beta 123
chr16_-_30023615 0.04 ENST00000564979.1
ENST00000563378.1
DOC2A
double C2-like domains, alpha
chr17_-_27054952 0.04 ENST00000580518.1
TLCD1
TLC domain containing 1
chr4_+_5527117 0.04 ENST00000505296.1
C4orf6
chromosome 4 open reading frame 6
chr19_+_15904761 0.04 ENST00000308940.8
OR10H5
olfactory receptor, family 10, subfamily H, member 5
chr12_+_120972606 0.04 ENST00000413266.2
RNF10
ring finger protein 10
chr19_+_58361185 0.04 ENST00000339656.5
ENST00000423137.1
ZNF587
zinc finger protein 587
chr13_+_49684445 0.03 ENST00000398316.3
FNDC3A
fibronectin type III domain containing 3A
chr7_-_73153161 0.03 ENST00000395147.4
ABHD11
abhydrolase domain containing 11
chr6_-_31763408 0.03 ENST00000444930.2
VARS
valyl-tRNA synthetase
chr9_-_86955598 0.03 ENST00000376238.4
SLC28A3
solute carrier family 28 (concentrative nucleoside transporter), member 3
chr20_+_44330651 0.03 ENST00000305479.2
WFDC13
WAP four-disulfide core domain 13
chr10_-_127511658 0.03 ENST00000368774.1
ENST00000368778.3
UROS
uroporphyrinogen III synthase
chr7_-_92219698 0.03 ENST00000438306.1
ENST00000445716.1
FAM133B
family with sequence similarity 133, member B
chr2_+_71357744 0.03 ENST00000498451.2
MPHOSPH10
M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
chr22_+_36113919 0.03 ENST00000249044.2
APOL5
apolipoprotein L, 5
chr2_+_113735575 0.02 ENST00000376489.2
ENST00000259205.4
IL36G
interleukin 36, gamma
chr16_-_68034470 0.02 ENST00000412757.2
DPEP2
dipeptidase 2
chr15_+_64386261 0.02 ENST00000560829.1
SNX1
sorting nexin 1
chr17_-_79604075 0.02 ENST00000374747.5
ENST00000539314.1
ENST00000331134.6
NPLOC4
nuclear protein localization 4 homolog (S. cerevisiae)
chr21_-_37432832 0.02 ENST00000332131.4
SETD4
SET domain containing 4
chr15_+_91473403 0.01 ENST00000394275.2
UNC45A
unc-45 homolog A (C. elegans)
chr5_+_172410757 0.01 ENST00000519374.1
ENST00000519911.1
ENST00000265093.4
ENST00000517669.1
ATP6V0E1
ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
chr14_-_77787198 0.01 ENST00000261534.4
POMT2
protein-O-mannosyltransferase 2
chr14_-_94970559 0.01 ENST00000556881.1
SERPINA12
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
chrX_-_9001351 0.01 ENST00000362066.3
FAM9B
family with sequence similarity 9, member B
chr5_+_76145826 0.01 ENST00000513010.1
S100Z
S100 calcium binding protein Z
chr1_+_13736907 0.01 ENST00000316412.5
PRAMEF20
PRAME family member 20
chr4_-_39033963 0.01 ENST00000381938.3
TMEM156
transmembrane protein 156
chr11_-_506316 0.01 ENST00000532055.1
ENST00000531540.1
RNH1
ribonuclease/angiogenin inhibitor 1
chr13_+_23993097 0.00 ENST00000443092.1
SACS-AS1
SACS antisense RNA 1
chr13_-_33112956 0.00 ENST00000505213.1
N4BP2L2
NEDD4 binding protein 2-like 2
chr17_+_78152274 0.00 ENST00000344227.2
ENST00000570421.1
CARD14
caspase recruitment domain family, member 14
chr1_-_153950098 0.00 ENST00000356648.1
JTB
jumping translocation breakpoint

Network of associatons between targets according to the STRING database.

First level regulatory network of NR1H2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.3 1.0 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.3 2.5 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.3 1.4 GO:0044861 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281) positive regulation of potassium ion import(GO:1903288)
0.2 0.7 GO:1902081 positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.2 1.2 GO:0036015 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.2 0.7 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 0.5 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.1 0.4 GO:0002155 regulation of thyroid hormone mediated signaling pathway(GO:0002155) kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.1 0.2 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.5 GO:0035803 egg coat formation(GO:0035803)
0.1 0.3 GO:0009447 putrescine catabolic process(GO:0009447)
0.1 0.9 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1 0.9 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.2 GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.1 0.2 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.1 0.2 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.1 0.4 GO:0048539 bone marrow development(GO:0048539)
0.1 0.4 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.4 GO:1904783 positive regulation of NMDA glutamate receptor activity(GO:1904783)
0.0 0.2 GO:1904647 response to rotenone(GO:1904647)
0.0 0.1 GO:0021849 neuroblast division in subventricular zone(GO:0021849) regulation of polarized epithelial cell differentiation(GO:0030860)
0.0 0.3 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.0 0.1 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.0 0.6 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.6 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 0.3 GO:0006686 sphingomyelin biosynthetic process(GO:0006686) positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.4 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.2 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.1 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.1 GO:2000395 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.0 0.1 GO:0031990 mRNA export from nucleus in response to heat stress(GO:0031990)
0.0 0.2 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.1 GO:1904823 pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.0 0.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.0 0.3 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.1 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.2 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.1 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.3 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.2 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.3 GO:0016180 snRNA processing(GO:0016180)
0.0 0.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0030689 Noc complex(GO:0030689)
0.1 1.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.7 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.3 GO:1990037 Lewy body core(GO:1990037)
0.0 0.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.3 GO:0060091 kinocilium(GO:0060091)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 2.5 GO:0005581 collagen trimer(GO:0005581)
0.0 0.4 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.1 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.1 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.3 0.9 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.2 1.1 GO:0004882 androgen receptor activity(GO:0004882)
0.2 0.5 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 0.3 GO:0004608 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.1 0.6 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.3 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 1.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 1.4 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.2 GO:0005124 scavenger receptor binding(GO:0005124)
0.1 1.0 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 0.2 GO:0030572 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.1 0.7 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.2 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1 0.3 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.5 GO:0032190 acrosin binding(GO:0032190)
0.0 0.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.4 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.3 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.1 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.0 0.1 GO:0015389 pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0047661 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.0 0.8 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.4 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.1 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.4 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 2.6 GO:0005518 collagen binding(GO:0005518)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.1 GO:0001851 complement component C3b binding(GO:0001851)
0.0 0.2 GO:0042609 CD4 receptor binding(GO:0042609)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 ST ADRENERGIC Adrenergic Pathway
0.0 2.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.6 PID IL3 PATHWAY IL3-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.9 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 1.0 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.2 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 1.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.4 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.7 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 1.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)