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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for NR1H4

Z-value: 0.48

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Transcription factors associated with NR1H4

Gene Symbol Gene ID Gene Info
NR1H4
ENSG00000012504.9 nuclear receptor subfamily 1 group H member 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR1H4hg19_v2_chr12_+_100867486_1008676520.414.1e-02Click!

Activity profile of NR1H4 motif

Sorted Z-values of NR1H4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_53809473 0.62 ENST00000575734.1
TMEM100
transmembrane protein 100
chr8_+_9046503 0.54 ENST00000512942.2
RP11-10A14.5
RP11-10A14.5
chr12_-_57914275 0.49 ENST00000547303.1
ENST00000552740.1
ENST00000547526.1
ENST00000551116.1
ENST00000346473.3
DDIT3
DNA-damage-inducible transcript 3
chr17_+_59529743 0.47 ENST00000589003.1
ENST00000393853.4
TBX4
T-box 4
chr11_+_7534999 0.44 ENST00000528947.1
ENST00000299492.4
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr20_-_45981138 0.44 ENST00000446994.2
ZMYND8
zinc finger, MYND-type containing 8
chr1_+_162351503 0.44 ENST00000458626.2
C1orf226
chromosome 1 open reading frame 226
chr10_-_95360983 0.39 ENST00000371464.3
RBP4
retinol binding protein 4, plasma
chr9_-_34372830 0.38 ENST00000379142.3
KIAA1161
KIAA1161
chr9_-_137809718 0.35 ENST00000371806.3
FCN1
ficolin (collagen/fibrinogen domain containing) 1
chr1_+_14026722 0.35 ENST00000376048.5
PRDM2
PR domain containing 2, with ZNF domain
chr1_+_36789335 0.35 ENST00000373137.2
RP11-268J15.5
RP11-268J15.5
chr2_-_106015527 0.35 ENST00000344213.4
ENST00000358129.4
FHL2
four and a half LIM domains 2
chr12_+_109273806 0.32 ENST00000228476.3
ENST00000547768.1
DAO
D-amino-acid oxidase
chr3_+_118866222 0.32 ENST00000490594.1
RP11-484M3.5
Uncharacterized protein
chr17_-_74023291 0.31 ENST00000586740.1
EVPL
envoplakin
chr1_+_26560676 0.31 ENST00000451429.2
ENST00000252992.4
CEP85
centrosomal protein 85kDa
chr12_-_7281469 0.30 ENST00000542370.1
ENST00000266560.3
RBP5
retinol binding protein 5, cellular
chr14_-_21492251 0.30 ENST00000554398.1
NDRG2
NDRG family member 2
chr14_-_21492113 0.29 ENST00000554094.1
NDRG2
NDRG family member 2
chr17_+_4853442 0.29 ENST00000522301.1
ENO3
enolase 3 (beta, muscle)
chr2_+_233877324 0.28 ENST00000409905.1
AC106876.2
Uncharacterized protein
chr3_-_160117301 0.27 ENST00000326448.7
ENST00000498409.1
ENST00000475677.1
ENST00000478536.1
IFT80
intraflagellar transport 80 homolog (Chlamydomonas)
chr3_+_54157480 0.27 ENST00000490478.1
CACNA2D3
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr6_+_107349392 0.26 ENST00000443043.1
ENST00000405204.2
ENST00000311381.5
C6orf203
chromosome 6 open reading frame 203
chr1_-_6557156 0.25 ENST00000537245.1
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr16_+_66995144 0.25 ENST00000394037.1
CES3
carboxylesterase 3
chr19_-_48867171 0.25 ENST00000377431.2
ENST00000436660.2
ENST00000541566.1
TMEM143
transmembrane protein 143
chr16_+_66995121 0.24 ENST00000303334.4
CES3
carboxylesterase 3
chr3_-_28390581 0.24 ENST00000479665.1
AZI2
5-azacytidine induced 2
chr22_+_31090793 0.24 ENST00000332585.6
ENST00000382310.3
ENST00000446658.2
OSBP2
oxysterol binding protein 2
chr2_-_64371546 0.23 ENST00000358912.4
PELI1
pellino E3 ubiquitin protein ligase 1
chr21_-_46515493 0.23 ENST00000600921.1
PRED57
HCG401283; PRED57 protein; Uncharacterized protein
chr10_-_119806085 0.23 ENST00000355624.3
RAB11FIP2
RAB11 family interacting protein 2 (class I)
chr3_+_183873098 0.22 ENST00000313143.3
DVL3
dishevelled segment polarity protein 3
chr9_-_44402427 0.22 ENST00000540551.1
BX088651.1
LOC100126582 protein; Uncharacterized protein
chr19_-_51220176 0.22 ENST00000359082.3
ENST00000293441.1
SHANK1
SH3 and multiple ankyrin repeat domains 1
chr3_+_111260856 0.22 ENST00000352690.4
CD96
CD96 molecule
chr19_-_48867291 0.21 ENST00000435956.3
TMEM143
transmembrane protein 143
chr3_-_38071122 0.21 ENST00000334661.4
PLCD1
phospholipase C, delta 1
chr4_+_25915822 0.21 ENST00000506197.2
SMIM20
small integral membrane protein 20
chr10_-_75634260 0.21 ENST00000372765.1
ENST00000351293.3
CAMK2G
calcium/calmodulin-dependent protein kinase II gamma
chr10_-_75634326 0.20 ENST00000322635.3
ENST00000444854.2
ENST00000423381.1
ENST00000322680.3
ENST00000394762.2
CAMK2G
calcium/calmodulin-dependent protein kinase II gamma
chr19_-_44860820 0.20 ENST00000354340.4
ENST00000337401.4
ENST00000587909.1
ZNF112
zinc finger protein 112
chr3_+_122296443 0.20 ENST00000464300.2
PARP15
poly (ADP-ribose) polymerase family, member 15
chr17_-_74023474 0.20 ENST00000301607.3
EVPL
envoplakin
chr4_+_25915896 0.20 ENST00000514384.1
SMIM20
small integral membrane protein 20
chr7_+_94139105 0.20 ENST00000297273.4
CASD1
CAS1 domain containing 1
chr12_-_8088871 0.19 ENST00000075120.7
SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr14_-_25103472 0.19 ENST00000216341.4
ENST00000382542.1
ENST00000382540.1
GZMB
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr1_+_86046433 0.19 ENST00000451137.2
CYR61
cysteine-rich, angiogenic inducer, 61
chr11_+_7273181 0.19 ENST00000318881.6
SYT9
synaptotagmin IX
chr14_-_25103388 0.18 ENST00000526004.1
ENST00000415355.3
GZMB
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr12_+_58013693 0.18 ENST00000320442.4
ENST00000379218.2
SLC26A10
solute carrier family 26, member 10
chr2_-_219433014 0.18 ENST00000418019.1
ENST00000454775.1
ENST00000338465.5
ENST00000415516.1
ENST00000258399.3
USP37
ubiquitin specific peptidase 37
chr14_+_101297740 0.18 ENST00000555928.1
MEG3
maternally expressed 3 (non-protein coding)
chr3_-_126327398 0.18 ENST00000383572.2
TXNRD3NB
thioredoxin reductase 3 neighbor
chr19_+_19496728 0.18 ENST00000537887.1
ENST00000417582.2
GATAD2A
GATA zinc finger domain containing 2A
chr18_+_3449330 0.18 ENST00000549253.1
TGIF1
TGFB-induced factor homeobox 1
chr3_+_52489606 0.17 ENST00000488380.1
ENST00000420808.2
NISCH
nischarin
chr6_+_118228657 0.17 ENST00000360388.4
SLC35F1
solute carrier family 35, member F1
chr4_-_171011084 0.17 ENST00000337664.4
AADAT
aminoadipate aminotransferase
chr6_-_49681235 0.17 ENST00000339139.4
CRISP2
cysteine-rich secretory protein 2
chr3_-_57113314 0.17 ENST00000338458.4
ENST00000468727.1
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr4_-_171011323 0.17 ENST00000509167.1
ENST00000353187.2
ENST00000507375.1
ENST00000515480.1
AADAT
aminoadipate aminotransferase
chr9_+_74526384 0.16 ENST00000334731.2
ENST00000377031.3
C9orf85
chromosome 9 open reading frame 85
chr20_+_62369623 0.16 ENST00000467211.1
RP4-583P15.14
RP4-583P15.14
chr19_+_35629702 0.16 ENST00000351325.4
FXYD1
FXYD domain containing ion transport regulator 1
chr19_+_10563567 0.16 ENST00000344979.3
PDE4A
phosphodiesterase 4A, cAMP-specific
chr1_+_12123414 0.16 ENST00000263932.2
TNFRSF8
tumor necrosis factor receptor superfamily, member 8
chr5_+_139927213 0.16 ENST00000310331.2
EIF4EBP3
eukaryotic translation initiation factor 4E binding protein 3
chr14_-_34931458 0.16 ENST00000298130.4
SPTSSA
serine palmitoyltransferase, small subunit A
chr5_+_137419581 0.15 ENST00000506684.1
ENST00000504809.1
ENST00000398754.1
WNT8A
wingless-type MMTV integration site family, member 8A
chr11_+_64073699 0.15 ENST00000405666.1
ENST00000468670.1
ESRRA
estrogen-related receptor alpha
chr11_-_10879572 0.15 ENST00000413761.2
ZBED5
zinc finger, BED-type containing 5
chr10_+_47083454 0.15 ENST00000374312.1
NPY4R
neuropeptide Y receptor Y4
chrX_+_106449862 0.15 ENST00000372453.3
ENST00000535523.1
PIH1D3
PIH1 domain containing 3
chr19_-_633576 0.15 ENST00000588649.2
POLRMT
polymerase (RNA) mitochondrial (DNA directed)
chr1_-_109584768 0.15 ENST00000357672.3
WDR47
WD repeat domain 47
chr6_+_96025341 0.14 ENST00000369293.1
ENST00000358812.4
MANEA
mannosidase, endo-alpha
chr1_+_44412577 0.14 ENST00000372343.3
IPO13
importin 13
chr1_-_109584716 0.14 ENST00000531337.1
ENST00000529074.1
ENST00000369965.4
WDR47
WD repeat domain 47
chr1_+_25598989 0.14 ENST00000454452.2
RHD
Rh blood group, D antigen
chr20_-_3644046 0.14 ENST00000290417.2
ENST00000319242.3
GFRA4
GDNF family receptor alpha 4
chr17_+_43318434 0.14 ENST00000587489.1
FMNL1
formin-like 1
chr17_-_27038765 0.13 ENST00000581289.1
ENST00000301039.2
PROCA1
protein interacting with cyclin A1
chr9_+_74526532 0.13 ENST00000486911.2
C9orf85
chromosome 9 open reading frame 85
chr1_-_225616515 0.13 ENST00000338179.2
ENST00000425080.1
LBR
lamin B receptor
chr5_+_132208014 0.13 ENST00000296877.2
LEAP2
liver expressed antimicrobial peptide 2
chrX_+_69454505 0.13 ENST00000374521.3
AWAT1
acyl-CoA wax alcohol acyltransferase 1
chr6_+_127588020 0.13 ENST00000309649.3
ENST00000610162.1
ENST00000610153.1
ENST00000608991.1
ENST00000480444.1
RNF146
ring finger protein 146
chr19_-_18385246 0.13 ENST00000608950.1
ENST00000600328.3
ENST00000600359.3
ENST00000392413.4
KIAA1683
KIAA1683
chr3_+_52489503 0.13 ENST00000345716.4
NISCH
nischarin
chr17_-_43568062 0.12 ENST00000421073.2
ENST00000584420.1
ENST00000589780.1
ENST00000430334.3
PLEKHM1
pleckstrin homology domain containing, family M (with RUN domain) member 1
chr17_-_73257667 0.12 ENST00000538886.1
ENST00000580799.1
ENST00000351904.7
ENST00000537686.1
GGA3
golgi-associated, gamma adaptin ear containing, ARF binding protein 3
chr11_-_10879593 0.12 ENST00000528289.1
ENST00000432999.2
ZBED5
zinc finger, BED-type containing 5
chr1_-_16539094 0.12 ENST00000270747.3
ARHGEF19
Rho guanine nucleotide exchange factor (GEF) 19
chrX_+_66764375 0.12 ENST00000374690.3
AR
androgen receptor
chr3_-_50383096 0.12 ENST00000442887.1
ENST00000360165.3
ZMYND10
zinc finger, MYND-type containing 10
chr22_+_20105012 0.12 ENST00000331821.3
ENST00000411892.1
RANBP1
RAN binding protein 1
chr5_+_79615790 0.12 ENST00000296739.4
SPZ1
spermatogenic leucine zipper 1
chr3_+_184055240 0.12 ENST00000383847.2
FAM131A
family with sequence similarity 131, member A
chr17_-_4852332 0.12 ENST00000572383.1
PFN1
profilin 1
chr1_-_109584608 0.11 ENST00000400794.3
ENST00000528747.1
ENST00000369962.3
ENST00000361054.3
WDR47
WD repeat domain 47
chr3_+_121903181 0.11 ENST00000498619.1
CASR
calcium-sensing receptor
chr15_+_83776137 0.11 ENST00000322019.9
TM6SF1
transmembrane 6 superfamily member 1
chr3_+_160117418 0.11 ENST00000465903.1
ENST00000485645.1
ENST00000360111.2
ENST00000472991.1
ENST00000467468.1
ENST00000469762.1
ENST00000489573.1
ENST00000462787.1
ENST00000490207.1
ENST00000485867.1
SMC4
structural maintenance of chromosomes 4
chr6_+_44126545 0.11 ENST00000532171.1
ENST00000398776.1
ENST00000542245.1
CAPN11
calpain 11
chr6_+_127587755 0.11 ENST00000368314.1
ENST00000476956.1
ENST00000609447.1
ENST00000356799.2
ENST00000477776.1
ENST00000609944.1
RNF146
ring finger protein 146
chr1_+_151483855 0.11 ENST00000427934.2
ENST00000271636.7
CGN
cingulin
chr3_-_126236605 0.11 ENST00000290868.2
UROC1
urocanate hydratase 1
chrX_-_47930980 0.11 ENST00000442455.3
ENST00000428686.1
ENST00000276054.4
ZNF630
zinc finger protein 630
chr6_+_152011628 0.11 ENST00000404742.1
ENST00000440973.1
ESR1
estrogen receptor 1
chr3_+_160117087 0.10 ENST00000357388.3
SMC4
structural maintenance of chromosomes 4
chr22_+_32149927 0.10 ENST00000437411.1
ENST00000535622.1
ENST00000536766.1
ENST00000400242.3
ENST00000266091.3
ENST00000400249.2
ENST00000400246.1
ENST00000382105.2
DEPDC5
DEP domain containing 5
chr19_+_1026298 0.10 ENST00000263097.4
CNN2
calponin 2
chr17_-_26879567 0.10 ENST00000581945.1
ENST00000444148.1
ENST00000301032.4
ENST00000335765.4
UNC119
unc-119 homolog (C. elegans)
chr16_-_67700594 0.10 ENST00000602644.1
ENST00000243878.4
ENKD1
enkurin domain containing 1
chr2_-_182545603 0.09 ENST00000295108.3
NEUROD1
neuronal differentiation 1
chr10_+_64564469 0.09 ENST00000373783.1
ADO
2-aminoethanethiol (cysteamine) dioxygenase
chr19_+_1026566 0.09 ENST00000348419.3
ENST00000565096.2
ENST00000562958.2
ENST00000562075.2
ENST00000607102.1
CNN2
calponin 2
chr2_-_74374995 0.09 ENST00000295326.4
BOLA3
bolA family member 3
chr19_-_36304201 0.09 ENST00000301175.3
PRODH2
proline dehydrogenase (oxidase) 2
chr3_+_183873240 0.09 ENST00000431765.1
DVL3
dishevelled segment polarity protein 3
chr22_-_21579843 0.09 ENST00000405188.4
GGT2
gamma-glutamyltransferase 2
chr7_+_49813255 0.08 ENST00000340652.4
VWC2
von Willebrand factor C domain containing 2
chr10_-_35104185 0.08 ENST00000374789.3
ENST00000374788.3
ENST00000346874.4
ENST00000374794.3
ENST00000350537.4
ENST00000374790.3
ENST00000374776.1
ENST00000374773.1
ENST00000545693.1
ENST00000545260.1
ENST00000340077.5
PARD3
par-3 family cell polarity regulator
chr12_-_56727676 0.08 ENST00000547572.1
ENST00000257931.5
ENST00000440411.3
PAN2
PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr5_+_145316120 0.08 ENST00000359120.4
SH3RF2
SH3 domain containing ring finger 2
chr22_-_50700140 0.08 ENST00000215659.8
MAPK12
mitogen-activated protein kinase 12
chr22_+_21321531 0.08 ENST00000405089.1
ENST00000335375.5
AIFM3
apoptosis-inducing factor, mitochondrion-associated, 3
chr1_-_25747283 0.08 ENST00000346452.4
ENST00000340849.4
ENST00000349438.4
ENST00000294413.7
ENST00000413854.1
ENST00000455194.1
ENST00000243186.6
ENST00000425135.1
RHCE
Rh blood group, CcEe antigens
chr5_+_149569520 0.08 ENST00000230671.2
ENST00000524041.1
SLC6A7
solute carrier family 6 (neurotransmitter transporter), member 7
chr17_-_73840415 0.08 ENST00000592386.1
ENST00000412096.2
ENST00000586147.1
UNC13D
unc-13 homolog D (C. elegans)
chrX_+_148793714 0.08 ENST00000355220.5
MAGEA11
melanoma antigen family A, 11
chr19_+_10196981 0.07 ENST00000591813.1
C19orf66
chromosome 19 open reading frame 66
chr19_+_1071203 0.07 ENST00000543365.1
HMHA1
histocompatibility (minor) HA-1
chr10_+_112404132 0.07 ENST00000369519.3
RBM20
RNA binding motif protein 20
chr13_+_27844464 0.07 ENST00000241463.4
RASL11A
RAS-like, family 11, member A
chr19_-_51054299 0.07 ENST00000599957.1
LRRC4B
leucine rich repeat containing 4B
chr3_+_52828805 0.07 ENST00000416872.2
ENST00000449956.2
ITIH3
inter-alpha-trypsin inhibitor heavy chain 3
chr11_-_7041466 0.07 ENST00000536068.1
ENST00000278314.4
ZNF214
zinc finger protein 214
chr3_+_111260954 0.07 ENST00000283285.5
CD96
CD96 molecule
chr14_-_24553834 0.07 ENST00000397002.2
NRL
neural retina leucine zipper
chr11_+_45868957 0.07 ENST00000443527.2
CRY2
cryptochrome 2 (photolyase-like)
chr5_-_177423243 0.06 ENST00000308304.2
PROP1
PROP paired-like homeobox 1
chr14_+_24025462 0.06 ENST00000556015.1
ENST00000554970.1
ENST00000554789.1
THTPA
thiamine triphosphatase
chr16_-_69166460 0.06 ENST00000523421.1
ENST00000448552.2
ENST00000306585.6
ENST00000567763.1
ENST00000522497.1
ENST00000522091.1
ENST00000519520.1
CHTF8
CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae)
chr4_+_184427235 0.06 ENST00000412117.1
ENST00000434682.2
ING2
inhibitor of growth family, member 2
chr14_+_24025194 0.06 ENST00000404535.3
ENST00000288014.6
THTPA
thiamine triphosphatase
chrX_+_47420516 0.06 ENST00000377045.4
ENST00000290277.6
ENST00000377039.2
ARAF
v-raf murine sarcoma 3611 viral oncogene homolog
chr3_-_58652523 0.06 ENST00000489857.1
ENST00000358781.2
FAM3D
family with sequence similarity 3, member D
chr3_-_128294929 0.06 ENST00000356020.2
C3orf27
chromosome 3 open reading frame 27
chr13_-_38172863 0.06 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
POSTN
periostin, osteoblast specific factor
chr14_-_54908043 0.06 ENST00000556113.1
ENST00000553660.1
ENST00000395573.4
ENST00000557690.1
ENST00000216416.4
CNIH1
cornichon family AMPA receptor auxiliary protein 1
chr3_-_113918254 0.06 ENST00000460779.1
DRD3
dopamine receptor D3
chr17_-_4852243 0.06 ENST00000225655.5
PFN1
profilin 1
chr15_-_75932528 0.06 ENST00000403490.1
IMP3
IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr1_+_32042105 0.06 ENST00000457433.2
ENST00000441210.2
TINAGL1
tubulointerstitial nephritis antigen-like 1
chr22_+_20104947 0.05 ENST00000402752.1
RANBP1
RAN binding protein 1
chr12_-_56727487 0.05 ENST00000548043.1
ENST00000425394.2
PAN2
PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr19_+_6361841 0.05 ENST00000596605.1
CLPP
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr4_+_152330390 0.05 ENST00000503146.1
ENST00000435205.1
FAM160A1
family with sequence similarity 160, member A1
chr19_-_11689752 0.05 ENST00000592659.1
ENST00000592828.1
ENST00000218758.5
ENST00000412435.2
ACP5
acid phosphatase 5, tartrate resistant
chr1_+_32042131 0.05 ENST00000271064.7
ENST00000537531.1
TINAGL1
tubulointerstitial nephritis antigen-like 1
chr11_-_33795893 0.05 ENST00000526785.1
ENST00000534136.1
ENST00000265651.3
ENST00000530401.1
ENST00000448981.2
FBXO3
F-box protein 3
chr3_-_28390415 0.05 ENST00000414162.1
ENST00000420543.2
AZI2
5-azacytidine induced 2
chr1_+_25599018 0.05 ENST00000417538.2
ENST00000357542.4
ENST00000568195.1
ENST00000342055.5
ENST00000423810.2
RHD
Rh blood group, D antigen
chr2_-_74780176 0.05 ENST00000409549.1
LOXL3
lysyl oxidase-like 3
chr14_+_22356029 0.05 ENST00000390437.2
TRAV12-2
T cell receptor alpha variable 12-2
chr8_-_131028660 0.05 ENST00000401979.2
ENST00000517654.1
ENST00000522361.1
ENST00000518167.1
FAM49B
family with sequence similarity 49, member B
chr3_+_122296465 0.05 ENST00000483793.1
PARP15
poly (ADP-ribose) polymerase family, member 15
chr7_+_99102573 0.05 ENST00000394170.2
ZKSCAN5
zinc finger with KRAB and SCAN domains 5
chr7_-_752074 0.05 ENST00000360274.4
PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
chr2_+_108905325 0.05 ENST00000438339.1
ENST00000409880.1
ENST00000437390.2
SULT1C2
sulfotransferase family, cytosolic, 1C, member 2
chr5_-_33892046 0.05 ENST00000352040.3
ADAMTS12
ADAM metallopeptidase with thrombospondin type 1 motif, 12
chr12_-_58135903 0.05 ENST00000257897.3
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr6_-_33771757 0.04 ENST00000507738.1
ENST00000266003.5
ENST00000430124.2
MLN
motilin
chr17_-_73975444 0.04 ENST00000293217.5
ENST00000537812.1
ACOX1
acyl-CoA oxidase 1, palmitoyl
chr11_-_62380199 0.04 ENST00000419857.1
ENST00000394773.2
EML3
echinoderm microtubule associated protein like 3
chr8_-_131028869 0.04 ENST00000518283.1
ENST00000519110.1
FAM49B
family with sequence similarity 49, member B
chr2_+_179345173 0.04 ENST00000234453.5
PLEKHA3
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3
chr3_-_15540055 0.04 ENST00000605797.1
ENST00000435459.2
COLQ
collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
chr16_-_30537839 0.04 ENST00000380412.5
ZNF768
zinc finger protein 768
chr1_-_16939976 0.04 ENST00000430580.2
NBPF1
neuroblastoma breakpoint family, member 1
chrX_-_106449656 0.04 ENST00000372466.4
ENST00000421752.1
ENST00000372461.3
NUP62CL
nucleoporin 62kDa C-terminal like
chr22_+_30163340 0.04 ENST00000330029.6
ENST00000401406.3
UQCR10
ubiquinol-cytochrome c reductase, complex III subunit X
chr1_+_29241027 0.04 ENST00000373797.1
EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr1_+_178482262 0.04 ENST00000367641.3
ENST00000367639.1
TEX35
testis expressed 35
chr5_+_139944396 0.04 ENST00000514199.1
SLC35A4
solute carrier family 35, member A4
chr5_+_139944024 0.04 ENST00000323146.3
SLC35A4
solute carrier family 35, member A4
chr4_+_123073464 0.04 ENST00000264501.4
KIAA1109
KIAA1109
chrX_+_7137475 0.04 ENST00000217961.4
STS
steroid sulfatase (microsomal), isozyme S
chr22_-_30234218 0.04 ENST00000307790.3
ENST00000542393.1
ENST00000397771.2
ASCC2
activating signal cointegrator 1 complex subunit 2
chr22_+_20105259 0.04 ENST00000416427.1
ENST00000421656.1
ENST00000423859.1
ENST00000418705.2
RANBP1
RAN binding protein 1
chr3_-_49158218 0.03 ENST00000417901.1
ENST00000306026.5
ENST00000434032.2
USP19
ubiquitin specific peptidase 19
chr3_-_28390298 0.03 ENST00000457172.1
AZI2
5-azacytidine induced 2
chr2_+_108905095 0.03 ENST00000251481.6
ENST00000326853.5
SULT1C2
sulfotransferase family, cytosolic, 1C, member 2
chr3_-_194119083 0.03 ENST00000401815.1
GP5
glycoprotein V (platelet)
chr5_-_83680603 0.03 ENST00000296591.5
EDIL3
EGF-like repeats and discoidin I-like domains 3

Network of associatons between targets according to the STRING database.

First level regulatory network of NR1H4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.1 0.3 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.1 0.5 GO:2000015 negative regulation of CREB transcription factor activity(GO:0032792) regulation of determination of dorsal identity(GO:2000015)
0.1 0.3 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.1 0.2 GO:0061316 canonical Wnt signaling pathway involved in heart development(GO:0061316) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317)
0.1 0.2 GO:0050894 determination of affect(GO:0050894)
0.1 0.4 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1 0.2 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.1 0.3 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.1 0.6 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.1 0.3 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 0.4 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.1 0.4 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.1 0.2 GO:0032639 TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
0.1 0.3 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.2 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:0060769 male genitalia morphogenesis(GO:0048808) lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599) positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769) male anatomical structure morphogenesis(GO:0090598)
0.0 0.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.6 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.0 0.2 GO:0010732 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.0 0.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.2 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.3 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 0.3 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.1 GO:2001287 negative regulation of clathrin-mediated endocytosis(GO:1900186) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.2 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
0.0 0.1 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.0 0.1 GO:0010166 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.1 GO:0048850 hypophysis morphogenesis(GO:0048850)
0.0 0.1 GO:0019557 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.4 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.2 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.4 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.0 0.3 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.4 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.1 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.0 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.3 GO:0048243 norepinephrine secretion(GO:0048243)
0.0 0.1 GO:2000568 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.0 0.1 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.0 0.1 GO:0006562 proline catabolic process(GO:0006562)
0.0 0.1 GO:0032416 negative regulation of sodium:proton antiporter activity(GO:0032416) musculoskeletal movement, spinal reflex action(GO:0050883)
0.0 0.2 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.0 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
0.0 0.2 GO:0019532 oxalate transport(GO:0019532)
0.0 0.1 GO:0098728 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.1 GO:0032571 response to vitamin K(GO:0032571) bone regeneration(GO:1990523)
0.0 0.1 GO:0060737 prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737) epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.0 0.2 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.1 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 0.4 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.2 GO:0000796 condensin complex(GO:0000796)
0.0 0.2 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.3 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:0009368 endopeptidase Clp complex(GO:0009368)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.1 0.2 GO:0031877 somatostatin receptor binding(GO:0031877)
0.0 0.2 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.1 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.0 0.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.5 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.7 GO:0019841 retinol binding(GO:0019841)
0.0 0.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.4 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0 0.6 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.0 0.2 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.0 0.1 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.0 0.1 GO:0004882 androgen receptor activity(GO:0004882)
0.0 0.1 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.2 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.4 GO:0071949 FAD binding(GO:0071949)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0023025 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.0 0.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.4 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.4 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex