Project

Inflammatory response time course, HUVEC (Wada et al., 2009)

Navigation
Downloads

Results for NR1I2

Z-value: 1.12

Motif logo

logo of

Transcription factors associated with NR1I2

Gene Symbol Gene ID Gene Info
NR1I2
ENSG00000144852.12 nuclear receptor subfamily 1 group I member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR1I2hg19_v2_chr3_+_119501557_119501557-0.135.4e-01Click!

Activity profile of NR1I2 motif

Sorted Z-values of NR1I2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr13_+_32605437 5.63 ENST00000380250.3
FRY
furry homolog (Drosophila)
chr3_+_8543393 5.13 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
LMCD1
LIM and cysteine-rich domains 1
chr3_+_8543561 4.39 ENST00000397386.3
LMCD1
LIM and cysteine-rich domains 1
chr6_+_142622991 4.08 ENST00000230173.6
ENST00000367608.2
GPR126
G protein-coupled receptor 126
chr8_-_93115445 4.01 ENST00000523629.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr6_+_142623063 3.92 ENST00000296932.8
ENST00000367609.3
GPR126
G protein-coupled receptor 126
chr1_+_61869748 3.73 ENST00000357977.5
NFIA
nuclear factor I/A
chr1_+_25944341 3.64 ENST00000263979.3
MAN1C1
mannosidase, alpha, class 1C, member 1
chr9_-_14313641 3.40 ENST00000380953.1
NFIB
nuclear factor I/B
chr10_-_131762105 3.38 ENST00000368648.3
ENST00000355311.5
EBF3
early B-cell factor 3
chr3_+_8543533 3.34 ENST00000454244.1
LMCD1
LIM and cysteine-rich domains 1
chr9_-_14314066 3.15 ENST00000397575.3
NFIB
nuclear factor I/B
chr10_-_33625154 3.09 ENST00000265371.4
NRP1
neuropilin 1
chr6_+_84743436 2.98 ENST00000257776.4
MRAP2
melanocortin 2 receptor accessory protein 2
chr4_-_149363662 2.97 ENST00000355292.3
ENST00000358102.3
NR3C2
nuclear receptor subfamily 3, group C, member 2
chr12_-_96184533 2.96 ENST00000343702.4
ENST00000344911.4
NTN4
netrin 4
chr18_+_3466248 2.95 ENST00000581029.1
ENST00000581442.1
ENST00000579007.1
RP11-838N2.4
RP11-838N2.4
chr9_-_14313893 2.88 ENST00000380921.3
ENST00000380959.3
NFIB
nuclear factor I/B
chr3_+_193853927 2.60 ENST00000232424.3
HES1
hes family bHLH transcription factor 1
chr14_-_90085458 2.56 ENST00000345097.4
ENST00000555855.1
ENST00000555353.1
FOXN3
forkhead box N3
chr9_-_134151915 2.29 ENST00000372271.3
FAM78A
family with sequence similarity 78, member A
chr4_+_30721968 2.19 ENST00000361762.2
PCDH7
protocadherin 7
chr10_-_125851961 2.18 ENST00000346248.5
CHST15
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr1_+_25943959 2.18 ENST00000374332.4
MAN1C1
mannosidase, alpha, class 1C, member 1
chr11_-_118122996 2.04 ENST00000525386.1
ENST00000527472.1
ENST00000278949.4
MPZL3
myelin protein zero-like 3
chr15_-_65067773 2.03 ENST00000300069.4
RBPMS2
RNA binding protein with multiple splicing 2
chr2_+_69240302 1.98 ENST00000303714.4
ANTXR1
anthrax toxin receptor 1
chr8_+_37654424 1.98 ENST00000315215.7
GPR124
G protein-coupled receptor 124
chr4_-_159080806 1.88 ENST00000590648.1
FAM198B
family with sequence similarity 198, member B
chr5_-_133747589 1.84 ENST00000458198.2
CDKN2AIPNL
CDKN2A interacting protein N-terminal like
chr15_+_96875657 1.83 ENST00000559679.1
ENST00000394171.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr5_+_73109339 1.77 ENST00000296799.4
ARHGEF28
Rho guanine nucleotide exchange factor (GEF) 28
chr10_+_94833642 1.69 ENST00000224356.4
ENST00000394139.1
CYP26A1
cytochrome P450, family 26, subfamily A, polypeptide 1
chr3_-_183735731 1.66 ENST00000334444.6
ABCC5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr4_-_159094194 1.65 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
FAM198B
family with sequence similarity 198, member B
chr3_-_58196688 1.62 ENST00000486455.1
DNASE1L3
deoxyribonuclease I-like 3
chr19_-_49552006 1.61 ENST00000391869.3
CGB1
chorionic gonadotropin, beta polypeptide 1
chr17_-_14683517 1.58 ENST00000379640.1
AC005863.1
AC005863.1
chr11_+_64879317 1.56 ENST00000526809.1
ENST00000279263.7
ENST00000524986.1
ENST00000534371.1
ENST00000540748.1
ENST00000525385.1
ENST00000345348.5
ENST00000531321.1
ENST00000529414.1
ENST00000526085.1
ENST00000530750.1
TM7SF2
transmembrane 7 superfamily member 2
chr15_+_96876340 1.52 ENST00000453270.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr1_+_16083154 1.48 ENST00000375771.1
FBLIM1
filamin binding LIM protein 1
chr3_-_58196939 1.47 ENST00000394549.2
ENST00000461914.3
DNASE1L3
deoxyribonuclease I-like 3
chr9_-_129884902 1.46 ENST00000373417.1
ANGPTL2
angiopoietin-like 2
chr9_-_129885010 1.46 ENST00000373425.3
ANGPTL2
angiopoietin-like 2
chr11_+_7618413 1.44 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chrX_+_135278908 1.43 ENST00000539015.1
ENST00000370683.1
FHL1
four and a half LIM domains 1
chr12_-_86230315 1.42 ENST00000361228.3
RASSF9
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr11_+_108093559 1.40 ENST00000278616.4
ATM
ataxia telangiectasia mutated
chr2_+_179149636 1.36 ENST00000409631.1
OSBPL6
oxysterol binding protein-like 6
chr2_-_208489275 1.31 ENST00000272839.3
ENST00000426075.1
METTL21A
methyltransferase like 21A
chr2_+_109223595 1.31 ENST00000410093.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr2_-_208489707 1.30 ENST00000448007.2
ENST00000432416.1
ENST00000411432.1
METTL21A
methyltransferase like 21A
chr5_-_112630598 1.30 ENST00000302475.4
MCC
mutated in colorectal cancers
chr1_-_211752073 1.29 ENST00000367001.4
SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr5_-_73937244 1.29 ENST00000302351.4
ENST00000510316.1
ENST00000508331.1
ENC1
ectodermal-neural cortex 1 (with BTB domain)
chr17_-_7531121 1.26 ENST00000573566.1
ENST00000269298.5
SAT2
spermidine/spermine N1-acetyltransferase family member 2
chr12_-_52585765 1.24 ENST00000313234.5
ENST00000394815.2
KRT80
keratin 80
chr2_-_89247338 1.23 ENST00000496168.1
IGKV1-5
immunoglobulin kappa variable 1-5
chr1_+_43291220 1.23 ENST00000372514.3
ERMAP
erythroblast membrane-associated protein (Scianna blood group)
chr5_+_78532003 1.22 ENST00000396137.4
JMY
junction mediating and regulatory protein, p53 cofactor
chr7_+_22766766 1.21 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
IL6
interleukin 6 (interferon, beta 2)
chr12_-_27167233 1.19 ENST00000535819.1
ENST00000543803.1
ENST00000535423.1
ENST00000539741.1
ENST00000343028.4
ENST00000545600.1
ENST00000543088.1
TM7SF3
transmembrane 7 superfamily member 3
chr1_+_229440129 1.18 ENST00000366688.3
SPHAR
S-phase response (cyclin related)
chr2_-_158732340 1.17 ENST00000539637.1
ENST00000413751.1
ENST00000434821.1
ENST00000424669.1
ACVR1
activin A receptor, type I
chr3_-_114343039 1.17 ENST00000481632.1
ZBTB20
zinc finger and BTB domain containing 20
chrX_+_72223352 1.15 ENST00000373521.2
ENST00000538388.1
PABPC1L2B
poly(A) binding protein, cytoplasmic 1-like 2B
chr16_+_67207838 1.14 ENST00000566871.1
ENST00000268605.7
NOL3
nucleolar protein 3 (apoptosis repressor with CARD domain)
chr3_+_25469802 1.14 ENST00000330688.4
RARB
retinoic acid receptor, beta
chr19_+_1248547 1.13 ENST00000586757.1
ENST00000300952.2
MIDN
midnolin
chrX_+_135279179 1.12 ENST00000370676.3
FHL1
four and a half LIM domains 1
chr8_-_29120580 1.12 ENST00000524189.1
KIF13B
kinesin family member 13B
chr7_-_30518387 1.12 ENST00000222823.4
ENST00000419601.1
NOD1
nucleotide-binding oligomerization domain containing 1
chr19_+_35485682 1.11 ENST00000599564.1
GRAMD1A
GRAM domain containing 1A
chr11_-_66445219 1.11 ENST00000525754.1
ENST00000531969.1
ENST00000524637.1
ENST00000531036.2
ENST00000310046.4
RBM4B
RNA binding motif protein 4B
chrX_-_72299258 1.11 ENST00000453389.1
ENST00000373519.1
PABPC1L2A
poly(A) binding protein, cytoplasmic 1-like 2A
chr16_+_67207872 1.09 ENST00000563258.1
ENST00000568146.1
NOL3
nucleolar protein 3 (apoptosis repressor with CARD domain)
chr19_-_39322497 1.09 ENST00000221418.4
ECH1
enoyl CoA hydratase 1, peroxisomal
chr1_-_17380630 1.09 ENST00000375499.3
SDHB
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
chr17_-_7082861 1.07 ENST00000269299.3
ASGR1
asialoglycoprotein receptor 1
chr2_-_43266680 1.06 ENST00000425212.1
ENST00000422351.1
ENST00000449766.1
AC016735.2
AC016735.2
chr12_-_6665200 1.06 ENST00000336604.4
ENST00000396840.2
ENST00000356896.4
IFFO1
intermediate filament family orphan 1
chr18_-_53253323 1.04 ENST00000540999.1
ENST00000563888.2
TCF4
transcription factor 4
chr6_-_31864977 1.03 ENST00000395728.3
ENST00000375528.4
EHMT2
euchromatic histone-lysine N-methyltransferase 2
chr6_+_159590423 1.02 ENST00000297267.9
ENST00000340366.6
FNDC1
fibronectin type III domain containing 1
chr12_-_8088871 1.02 ENST00000075120.7
SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr17_+_38497640 1.00 ENST00000394086.3
RARA
retinoic acid receptor, alpha
chr6_-_8102714 1.00 ENST00000502429.1
ENST00000429723.2
ENST00000507463.1
ENST00000379715.5
EEF1E1
eukaryotic translation elongation factor 1 epsilon 1
chr18_-_53253112 1.00 ENST00000568673.1
ENST00000562847.1
ENST00000568147.1
TCF4
transcription factor 4
chr5_+_154320623 0.99 ENST00000523037.1
ENST00000265229.8
ENST00000439747.3
ENST00000522038.1
MRPL22
mitochondrial ribosomal protein L22
chr2_-_69870747 0.96 ENST00000409068.1
AAK1
AP2 associated kinase 1
chr7_+_135611542 0.96 ENST00000416501.1
AC015987.2
AC015987.2
chrX_+_149531524 0.96 ENST00000370401.2
MAMLD1
mastermind-like domain containing 1
chr5_+_175298573 0.96 ENST00000512824.1
CPLX2
complexin 2
chr8_-_124286495 0.95 ENST00000297857.2
ZHX1
zinc fingers and homeoboxes 1
chr4_+_71600144 0.93 ENST00000502653.1
RUFY3
RUN and FYVE domain containing 3
chr8_-_124286735 0.93 ENST00000395571.3
ZHX1
zinc fingers and homeoboxes 1
chr2_+_109237717 0.93 ENST00000409441.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr14_-_65769392 0.92 ENST00000555736.1
CTD-2509G16.5
CTD-2509G16.5
chr12_-_15104040 0.91 ENST00000541644.1
ENST00000545895.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr18_-_52989525 0.89 ENST00000457482.3
TCF4
transcription factor 4
chr3_+_25469724 0.89 ENST00000437042.2
RARB
retinoic acid receptor, beta
chr3_+_97868170 0.88 ENST00000437310.1
OR5H14
olfactory receptor, family 5, subfamily H, member 14
chr1_+_196912902 0.87 ENST00000476712.2
ENST00000367415.5
CFHR2
complement factor H-related 2
chr1_+_196788887 0.87 ENST00000320493.5
ENST00000367424.4
ENST00000367421.3
CFHR1
CFHR2
complement factor H-related 1
complement factor H-related 2
chr12_-_68696652 0.87 ENST00000539972.1
MDM1
Mdm1 nuclear protein homolog (mouse)
chr1_-_55089191 0.87 ENST00000302250.2
ENST00000371304.2
FAM151A
family with sequence similarity 151, member A
chr2_-_86790593 0.86 ENST00000263856.4
ENST00000409225.2
CHMP3
charged multivesicular body protein 3
chr3_-_49722523 0.86 ENST00000448220.1
MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr2_+_179184955 0.85 ENST00000315022.2
OSBPL6
oxysterol binding protein-like 6
chr4_-_110723194 0.84 ENST00000394635.3
CFI
complement factor I
chr13_-_33112823 0.83 ENST00000504114.1
N4BP2L2
NEDD4 binding protein 2-like 2
chr4_-_110723335 0.83 ENST00000394634.2
CFI
complement factor I
chr1_+_159557607 0.82 ENST00000255040.2
APCS
amyloid P component, serum
chr2_-_86790472 0.82 ENST00000409727.1
CHMP3
charged multivesicular body protein 3
chr16_+_28875126 0.81 ENST00000359285.5
ENST00000538342.1
SH2B1
SH2B adaptor protein 1
chr15_+_39873268 0.81 ENST00000397591.2
ENST00000260356.5
THBS1
thrombospondin 1
chr7_-_107642348 0.80 ENST00000393561.1
LAMB1
laminin, beta 1
chr1_+_110754094 0.79 ENST00000369787.3
ENST00000413138.3
ENST00000438661.2
KCNC4
potassium voltage-gated channel, Shaw-related subfamily, member 4
chr2_-_113999260 0.79 ENST00000468980.2
PAX8
paired box 8
chr7_+_101460882 0.77 ENST00000292535.7
ENST00000549414.2
ENST00000550008.2
ENST00000546411.2
ENST00000556210.1
CUX1
cut-like homeobox 1
chr4_-_110723134 0.77 ENST00000510800.1
ENST00000512148.1
CFI
complement factor I
chr11_+_66624527 0.76 ENST00000393952.3
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr1_+_201979645 0.75 ENST00000367284.5
ENST00000367283.3
ELF3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr16_-_31228680 0.75 ENST00000302964.3
PYDC1
PYD (pyrin domain) containing 1
chr14_+_88852059 0.75 ENST00000045347.7
SPATA7
spermatogenesis associated 7
chr12_-_95510743 0.74 ENST00000551521.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr7_-_32931623 0.73 ENST00000452926.1
KBTBD2
kelch repeat and BTB (POZ) domain containing 2
chr18_-_19284724 0.73 ENST00000580981.1
ENST00000289119.2
ABHD3
abhydrolase domain containing 3
chr5_+_134074231 0.72 ENST00000514518.1
CAMLG
calcium modulating ligand
chrX_+_28605516 0.72 ENST00000378993.1
IL1RAPL1
interleukin 1 receptor accessory protein-like 1
chr2_-_70475701 0.72 ENST00000282574.4
TIA1
TIA1 cytotoxic granule-associated RNA binding protein
chr22_-_29784519 0.71 ENST00000357586.2
ENST00000356015.2
ENST00000432560.2
ENST00000317368.7
AP1B1
adaptor-related protein complex 1, beta 1 subunit
chr9_+_139981379 0.71 ENST00000371589.4
MAN1B1
mannosidase, alpha, class 1B, member 1
chr20_+_54933971 0.71 ENST00000371384.3
ENST00000437418.1
FAM210B
family with sequence similarity 210, member B
chr22_+_50354104 0.70 ENST00000360612.4
PIM3
pim-3 oncogene
chr1_-_154458520 0.70 ENST00000486773.1
SHE
Src homology 2 domain containing E
chr8_+_21911054 0.70 ENST00000519850.1
ENST00000381470.3
DMTN
dematin actin binding protein
chr17_-_7082668 0.69 ENST00000573083.1
ENST00000574388.1
ASGR1
asialoglycoprotein receptor 1
chr10_+_76586348 0.69 ENST00000372724.1
ENST00000287239.4
ENST00000372714.1
KAT6B
K(lysine) acetyltransferase 6B
chr12_-_14849470 0.69 ENST00000261170.3
GUCY2C
guanylate cyclase 2C (heat stable enterotoxin receptor)
chr10_+_112257596 0.68 ENST00000369583.3
DUSP5
dual specificity phosphatase 5
chr18_-_53255766 0.68 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
TCF4
transcription factor 4
chr1_-_234667504 0.67 ENST00000421207.1
ENST00000435574.1
RP5-855F14.1
RP5-855F14.1
chr20_+_3776371 0.65 ENST00000245960.5
CDC25B
cell division cycle 25B
chrX_+_135251835 0.64 ENST00000456445.1
FHL1
four and a half LIM domains 1
chr11_+_3876859 0.63 ENST00000300737.4
STIM1
stromal interaction molecule 1
chr5_+_175298674 0.63 ENST00000514150.1
CPLX2
complexin 2
chr6_-_107077347 0.63 ENST00000369063.3
ENST00000539449.1
RTN4IP1
reticulon 4 interacting protein 1
chr2_+_69240511 0.62 ENST00000409349.3
ANTXR1
anthrax toxin receptor 1
chr1_-_246670519 0.62 ENST00000388985.4
ENST00000490107.1
SMYD3
SET and MYND domain containing 3
chr17_-_27503770 0.62 ENST00000533112.1
MYO18A
myosin XVIIIA
chr2_-_220083076 0.61 ENST00000295750.4
ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr3_+_56591184 0.60 ENST00000422222.1
ENST00000394672.3
ENST00000326595.7
CCDC66
coiled-coil domain containing 66
chr2_-_70475730 0.59 ENST00000445587.1
ENST00000433529.2
ENST00000415783.2
TIA1
TIA1 cytotoxic granule-associated RNA binding protein
chr8_+_124084899 0.59 ENST00000287380.1
ENST00000309336.3
ENST00000519418.1
ENST00000327098.5
ENST00000522420.1
ENST00000521676.1
ENST00000378080.2
TBC1D31
TBC1 domain family, member 31
chr1_+_222817629 0.59 ENST00000340535.7
MIA3
melanoma inhibitory activity family, member 3
chr16_-_47495170 0.58 ENST00000320640.6
ENST00000544001.2
ITFG1
integrin alpha FG-GAP repeat containing 1
chr20_-_46415297 0.58 ENST00000467815.1
ENST00000359930.4
SULF2
sulfatase 2
chr10_+_80828774 0.58 ENST00000334512.5
ZMIZ1
zinc finger, MIZ-type containing 1
chr13_-_30424821 0.57 ENST00000380680.4
UBL3
ubiquitin-like 3
chr19_+_41117770 0.57 ENST00000601032.1
LTBP4
latent transforming growth factor beta binding protein 4
chr21_+_17442799 0.55 ENST00000602580.1
ENST00000458468.1
ENST00000602935.1
LINC00478
long intergenic non-protein coding RNA 478
chr2_+_65663812 0.55 ENST00000606978.1
ENST00000377977.3
ENST00000536804.1
AC074391.1
AC074391.1
chr6_-_85474219 0.55 ENST00000369663.5
TBX18
T-box 18
chr17_-_4806369 0.55 ENST00000293780.4
CHRNE
cholinergic receptor, nicotinic, epsilon (muscle)
chr15_+_42696992 0.55 ENST00000561817.1
CAPN3
calpain 3, (p94)
chr5_-_176433350 0.54 ENST00000377227.4
ENST00000377219.2
UIMC1
ubiquitin interaction motif containing 1
chr6_+_79577189 0.54 ENST00000369940.2
IRAK1BP1
interleukin-1 receptor-associated kinase 1 binding protein 1
chr7_-_38948774 0.53 ENST00000395969.2
ENST00000414632.1
ENST00000310301.4
VPS41
vacuolar protein sorting 41 homolog (S. cerevisiae)
chr4_-_152682129 0.52 ENST00000512306.1
ENST00000508611.1
ENST00000515812.1
ENST00000263985.6
PET112
PET112 homolog (yeast)
chr7_-_94285402 0.52 ENST00000428696.2
ENST00000445866.2
SGCE
sarcoglycan, epsilon
chr6_+_155537771 0.52 ENST00000275246.7
TIAM2
T-cell lymphoma invasion and metastasis 2
chr19_-_8809139 0.51 ENST00000324436.3
ACTL9
actin-like 9
chr11_+_118230287 0.51 ENST00000252108.3
ENST00000431736.2
UBE4A
ubiquitination factor E4A
chr3_+_14989186 0.50 ENST00000435454.1
ENST00000323373.6
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr7_-_105332084 0.50 ENST00000472195.1
ATXN7L1
ataxin 7-like 1
chr20_+_3776936 0.50 ENST00000439880.2
CDC25B
cell division cycle 25B
chr1_-_53387386 0.49 ENST00000467988.1
ENST00000358358.5
ENST00000371522.4
ECHDC2
enoyl CoA hydratase domain containing 2
chr8_-_120685608 0.49 ENST00000427067.2
ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr4_+_71859156 0.49 ENST00000286648.5
ENST00000504730.1
ENST00000504952.1
DCK
deoxycytidine kinase
chr17_+_3323862 0.48 ENST00000291231.1
OR3A3
olfactory receptor, family 3, subfamily A, member 3
chr1_+_152758690 0.48 ENST00000368771.1
ENST00000368770.3
LCE1E
late cornified envelope 1E
chr17_+_75137460 0.48 ENST00000587820.1
SEC14L1
SEC14-like 1 (S. cerevisiae)
chr15_-_52404921 0.48 ENST00000561198.1
ENST00000260442.3
BCL2L10
BCL2-like 10 (apoptosis facilitator)
chr8_-_100905925 0.48 ENST00000518171.1
COX6C
cytochrome c oxidase subunit VIc
chr3_+_183894566 0.48 ENST00000439647.1
AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr5_+_134074191 0.47 ENST00000297156.2
CAMLG
calcium modulating ligand
chr8_+_11666649 0.47 ENST00000528643.1
ENST00000525777.1
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chrX_+_16668278 0.46 ENST00000380200.3
S100G
S100 calcium binding protein G
chr1_-_47069955 0.46 ENST00000341183.5
ENST00000496619.1
MKNK1
MAP kinase interacting serine/threonine kinase 1
chr11_+_120207787 0.45 ENST00000397843.2
ENST00000356641.3
ARHGEF12
Rho guanine nucleotide exchange factor (GEF) 12
chr5_+_180650271 0.45 ENST00000351937.5
ENST00000315073.5
TRIM41
tripartite motif containing 41
chr19_+_7011509 0.45 ENST00000377296.3
AC025278.1
Uncharacterized protein
chr6_+_73331918 0.44 ENST00000402622.2
ENST00000355635.3
ENST00000403813.2
ENST00000414165.2
KCNQ5
potassium voltage-gated channel, KQT-like subfamily, member 5
chr16_+_47495201 0.44 ENST00000566044.1
ENST00000455779.1
PHKB
phosphorylase kinase, beta
chr12_+_58013693 0.44 ENST00000320442.4
ENST00000379218.2
SLC26A10
solute carrier family 26, member 10
chr16_-_57520378 0.44 ENST00000340099.4
DOK4
docking protein 4
chr2_-_65593784 0.44 ENST00000443619.2
SPRED2
sprouty-related, EVH1 domain containing 2
chr12_+_6494285 0.44 ENST00000541102.1
LTBR
lymphotoxin beta receptor (TNFR superfamily, member 3)
chr7_+_129007964 0.44 ENST00000460109.1
ENST00000474594.1
ENST00000446212.1
AHCYL2
adenosylhomocysteinase-like 2

Network of associatons between targets according to the STRING database.

First level regulatory network of NR1I2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 9.4 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
1.0 5.8 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.9 2.7 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.9 2.6 GO:0021558 trochlear nerve development(GO:0021558) auditory receptor cell fate determination(GO:0042668) negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of pro-B cell differentiation(GO:2000974)
0.8 3.3 GO:0009956 radial pattern formation(GO:0009956)
0.7 2.2 GO:0014876 response to injury involved in regulation of muscle adaptation(GO:0014876)
0.7 5.6 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.6 3.1 GO:1905040 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) endothelial tip cell fate specification(GO:0097102) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.6 3.0 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.5 12.9 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.5 1.4 GO:1904882 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434) telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.4 1.7 GO:0034653 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.4 1.7 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.4 1.2 GO:2000366 hepatic immune response(GO:0002384) regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.4 1.2 GO:2000017 positive regulation of determination of dorsal identity(GO:2000017)
0.4 1.4 GO:0009447 putrescine catabolic process(GO:0009447)
0.3 1.0 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.3 0.8 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.3 1.0 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.3 1.0 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.2 1.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.2 0.7 GO:0036509 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.2 1.5 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.2 0.6 GO:1903028 positive regulation of opsonization(GO:1903028)
0.2 2.0 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.2 0.8 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.2 1.1 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.2 0.7 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.2 1.3 GO:0097501 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.2 0.6 GO:0060823 canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060823)
0.2 3.1 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.1 0.6 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 1.1 GO:0002606 positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.1 1.7 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.1 3.7 GO:0072189 ureter development(GO:0072189)
0.1 2.0 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.1 0.9 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.1 0.4 GO:0006059 hexitol metabolic process(GO:0006059)
0.1 0.9 GO:0071461 cellular response to redox state(GO:0071461)
0.1 1.3 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.7 GO:0006789 bilirubin conjugation(GO:0006789)
0.1 2.6 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 0.7 GO:0070560 protein secretion by platelet(GO:0070560)
0.1 1.7 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.1 1.4 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.1 0.7 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.1 0.3 GO:0031133 regulation of axon diameter(GO:0031133)
0.1 1.5 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 1.2 GO:0007144 female meiosis I(GO:0007144)
0.1 0.4 GO:0003095 pressure natriuresis(GO:0003095)
0.1 0.3 GO:0061009 common bile duct development(GO:0061009)
0.1 1.1 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.1 0.6 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.5 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 0.3 GO:2001162 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.1 0.6 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.5 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.1 0.4 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.1 0.3 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.1 0.3 GO:0002424 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072)
0.1 0.2 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1 0.7 GO:0060523 prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737)
0.1 0.5 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.1 0.8 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.1 0.4 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 0.4 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 0.7 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.1 4.0 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 0.5 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.5 GO:0002857 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.1 1.2 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1 0.9 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 1.6 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.1 0.4 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.7 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 0.4 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.1 0.7 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.1 0.4 GO:0030242 pexophagy(GO:0030242)
0.1 0.8 GO:0060056 mammary gland involution(GO:0060056)
0.1 0.9 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 1.6 GO:0030728 ovulation(GO:0030728)
0.1 0.8 GO:0006105 succinate metabolic process(GO:0006105)
0.1 0.2 GO:0042369 vitamin D catabolic process(GO:0042369)
0.1 0.1 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.1 3.0 GO:0097009 energy homeostasis(GO:0097009)
0.1 0.7 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 0.4 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 3.2 GO:0003254 regulation of membrane depolarization(GO:0003254)
0.0 0.1 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.6 GO:0015886 heme transport(GO:0015886)
0.0 0.2 GO:0061591 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 1.0 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 1.1 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.7 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 2.6 GO:1901224 positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0 2.0 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.6 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.6 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.3 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 0.2 GO:0060526 prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.0 0.5 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 1.0 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.4 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.2 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.0 1.5 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 1.0 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.6 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.4 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.0 0.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:0006711 estrogen catabolic process(GO:0006711)
0.0 1.5 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.5 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.5 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0 0.3 GO:0001765 membrane raft assembly(GO:0001765)
0.0 0.9 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 1.8 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 0.7 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 4.2 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.2 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.4 GO:0046415 urate transport(GO:0015747) urate metabolic process(GO:0046415)
0.0 0.5 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.5 GO:0009157 deoxyribonucleoside monophosphate biosynthetic process(GO:0009157)
0.0 0.3 GO:2000318 positive regulation of T-helper 17 type immune response(GO:2000318)
0.0 0.3 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.3 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.1 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.9 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.1 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.2 GO:1902001 carnitine shuttle(GO:0006853) fatty acid transmembrane transport(GO:1902001)
0.0 0.3 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 1.2 GO:0001881 receptor recycling(GO:0001881)
0.0 0.4 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.3 GO:0045176 apical protein localization(GO:0045176)
0.0 0.1 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.0 GO:0046880 positive regulation of gonadotropin secretion(GO:0032278) positive regulation of luteinizing hormone secretion(GO:0033686) regulation of follicle-stimulating hormone secretion(GO:0046880) positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.0 0.6 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.8 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 1.3 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 2.1 GO:0018022 peptidyl-lysine methylation(GO:0018022)
0.0 0.7 GO:0042407 cristae formation(GO:0042407)
0.0 0.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.3 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 1.2 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.9 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 1.4 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 2.7 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.7 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.8 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 0.1 GO:0021678 third ventricle development(GO:0021678)
0.0 0.8 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.7 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.0 0.2 GO:0003416 endochondral bone growth(GO:0003416) bone growth(GO:0098868)
0.0 1.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 3.0 GO:0065004 protein-DNA complex assembly(GO:0065004)
0.0 0.2 GO:0030238 male sex determination(GO:0030238)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 9.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.4 1.2 GO:0048179 activin receptor complex(GO:0048179)
0.3 1.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.3 3.1 GO:0097443 sorting endosome(GO:0097443)
0.3 0.8 GO:0005607 laminin-2 complex(GO:0005607)
0.2 0.8 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.2 1.6 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.2 1.4 GO:0097165 nuclear stress granule(GO:0097165)
0.1 1.7 GO:0000815 ESCRT III complex(GO:0000815)
0.1 6.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 0.9 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 0.5 GO:0033263 CORVET complex(GO:0033263)
0.1 2.1 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 1.4 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 2.7 GO:0031527 filopodium membrane(GO:0031527)
0.1 0.3 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.1 0.7 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 2.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.8 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.2 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.1 0.5 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.7 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 1.1 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.5 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.4 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 1.0 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.6 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.7 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.7 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0005602 complement component C1 complex(GO:0005602)
0.0 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.7 GO:0031095 spectrin-associated cytoskeleton(GO:0014731) platelet dense tubular network membrane(GO:0031095)
0.0 0.4 GO:0031906 late endosome lumen(GO:0031906)
0.0 2.2 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 4.6 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.3 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 1.2 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.7 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 5.7 GO:0030427 site of polarized growth(GO:0030427)
0.0 1.4 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 1.6 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.7 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 2.5 GO:0005604 basement membrane(GO:0005604)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.5 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 2.3 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.1 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.9 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 1.0 GO:0043195 terminal bouton(GO:0043195)
0.0 0.2 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.8 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.8 GO:0030315 T-tubule(GO:0030315)
0.0 0.2 GO:0030118 clathrin coat(GO:0030118)
0.0 0.4 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.7 2.2 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.6 6.5 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.5 1.6 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.4 1.1 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.3 1.7 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.3 3.0 GO:0043237 laminin-1 binding(GO:0043237)
0.3 3.1 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.3 3.6 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.3 0.8 GO:0070052 collagen V binding(GO:0070052)
0.3 1.0 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.2 1.2 GO:0016361 activin receptor activity, type I(GO:0016361)
0.2 2.2 GO:0035877 death effector domain binding(GO:0035877)
0.2 1.8 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.2 0.6 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.2 1.4 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.2 0.6 GO:0005174 CD40 receptor binding(GO:0005174)
0.2 0.5 GO:0004137 deoxycytidine kinase activity(GO:0004137)
0.2 3.0 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 1.0 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 0.4 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.7 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 0.8 GO:0039552 RIG-I binding(GO:0039552)
0.1 1.2 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 4.2 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.4 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.1 0.5 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1 0.4 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.6 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.1 0.5 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 0.8 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.1 1.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.4 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.6 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 1.7 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.1 0.4 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.1 0.7 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)
0.1 0.4 GO:0004335 galactokinase activity(GO:0004335)
0.1 0.9 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 0.6 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.2 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1 0.5 GO:0005499 vitamin D binding(GO:0005499)
0.1 1.7 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 0.9 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.7 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.4 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 0.4 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 1.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.1 0.3 GO:0004802 transketolase activity(GO:0004802)
0.1 0.6 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1 1.0 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 1.5 GO:0031432 titin binding(GO:0031432)
0.1 1.0 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 1.5 GO:0031005 filamin binding(GO:0031005)
0.1 1.1 GO:0005549 odorant binding(GO:0005549)
0.1 0.4 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.3 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.1 0.4 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.3 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.7 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.5 GO:0089720 caspase binding(GO:0089720)
0.0 17.6 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 2.1 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.4 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.1 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 0.7 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 1.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.4 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.5 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 2.7 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.0 3.0 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 1.1 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 2.4 GO:0016278 lysine N-methyltransferase activity(GO:0016278)
0.0 0.2 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.0 2.2 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.5 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.4 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.5 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 3.6 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.8 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 9.6 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.2 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.4 GO:0048156 tau protein binding(GO:0048156)
0.0 0.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 2.0 GO:0005518 collagen binding(GO:0005518)
0.0 0.4 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 0.5 GO:0035173 histone kinase activity(GO:0035173) lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 1.0 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.9 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.3 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.2 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 1.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.4 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.4 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.7 GO:0043621 protein self-association(GO:0043621)
0.0 0.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 18.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 2.7 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 2.7 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 1.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 2.9 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 4.0 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 1.2 ST STAT3 PATHWAY STAT3 Pathway
0.1 1.2 PID ALK2 PATHWAY ALK2 signaling events
0.0 2.7 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 4.1 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.2 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 1.8 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 1.1 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.7 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.7 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.5 PID ARF 3PATHWAY Arf1 pathway
0.0 0.4 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.5 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.8 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.0 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.5 PID ATM PATHWAY ATM pathway
0.0 1.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.4 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.2 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.4 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.8 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.6 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.6 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.6 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 9.4 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 2.7 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 3.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.4 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 5.7 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.1 1.7 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 1.9 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 1.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 2.0 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.7 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 3.1 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 2.2 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 1.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.6 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 1.0 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 3.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.5 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 1.1 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 1.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.7 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 1.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.7 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.8 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.8 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 2.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 1.0 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.8 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.5 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.4 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.5 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.7 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.9 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.4 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 2.7 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.0 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.5 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.2 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.0 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.4 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.0 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.7 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.5 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels