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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for NR2E1

Z-value: 0.78

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Transcription factors associated with NR2E1

Gene Symbol Gene ID Gene Info
NR2E1
ENSG00000112333.7 nuclear receptor subfamily 2 group E member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR2E1hg19_v2_chr6_+_108487245_1084872620.087.2e-01Click!

Activity profile of NR2E1 motif

Sorted Z-values of NR2E1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_21786179 3.18 ENST00000377113.5
CASC10
cancer susceptibility candidate 10
chr1_-_169703203 2.22 ENST00000333360.7
ENST00000367781.4
ENST00000367782.4
ENST00000367780.4
ENST00000367779.4
SELE
selectin E
chr4_+_4861385 1.62 ENST00000382723.4
MSX1
msh homeobox 1
chr9_-_16728161 1.37 ENST00000603713.1
ENST00000603313.1
BNC2
basonuclin 2
chr1_+_25944341 1.14 ENST00000263979.3
MAN1C1
mannosidase, alpha, class 1C, member 1
chr3_-_64673289 0.91 ENST00000295903.4
ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr5_-_88179302 0.90 ENST00000504921.2
MEF2C
myocyte enhancer factor 2C
chr3_-_64673668 0.87 ENST00000498707.1
ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr8_+_86121448 0.85 ENST00000520225.1
E2F5
E2F transcription factor 5, p130-binding
chr16_-_15180257 0.81 ENST00000540462.1
RRN3
RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
chr3_-_18466026 0.72 ENST00000417717.2
SATB1
SATB homeobox 1
chr9_-_3469181 0.71 ENST00000366116.2
AL365202.1
Uncharacterized protein
chr2_-_208030647 0.67 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr12_+_79258547 0.64 ENST00000457153.2
SYT1
synaptotagmin I
chr1_+_212738676 0.64 ENST00000366981.4
ENST00000366987.2
ATF3
activating transcription factor 3
chr12_+_79258444 0.62 ENST00000261205.4
SYT1
synaptotagmin I
chr12_-_82152420 0.60 ENST00000552948.1
ENST00000548586.1
PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chrX_+_10031499 0.59 ENST00000454666.1
WWC3
WWC family member 3
chr5_-_11589131 0.58 ENST00000511377.1
CTNND2
catenin (cadherin-associated protein), delta 2
chr11_-_128457446 0.58 ENST00000392668.4
ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
chr5_-_88178964 0.56 ENST00000513252.1
ENST00000508569.1
ENST00000510942.1
ENST00000506554.1
MEF2C
myocyte enhancer factor 2C
chr5_-_88179017 0.54 ENST00000514028.1
ENST00000514015.1
ENST00000503075.1
ENST00000437473.2
MEF2C
myocyte enhancer factor 2C
chr10_+_35484793 0.54 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
CREM
cAMP responsive element modulator
chr16_-_66952779 0.53 ENST00000570262.1
ENST00000394055.3
ENST00000299752.4
CDH16
cadherin 16, KSP-cadherin
chr12_-_58220078 0.51 ENST00000549039.1
CTDSP2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr16_-_66952742 0.50 ENST00000565235.2
ENST00000568632.1
ENST00000565796.1
CDH16
cadherin 16, KSP-cadherin
chr1_+_32042105 0.47 ENST00000457433.2
ENST00000441210.2
TINAGL1
tubulointerstitial nephritis antigen-like 1
chr14_-_35344093 0.47 ENST00000382422.2
BAZ1A
bromodomain adjacent to zinc finger domain, 1A
chr13_-_21634421 0.46 ENST00000542899.1
LATS2
large tumor suppressor kinase 2
chr15_-_74374891 0.46 ENST00000290438.3
GOLGA6A
golgin A6 family, member A
chr9_-_75567962 0.46 ENST00000297785.3
ENST00000376939.1
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr5_-_11588907 0.45 ENST00000513598.1
ENST00000503622.1
CTNND2
catenin (cadherin-associated protein), delta 2
chr6_+_106546808 0.43 ENST00000369089.3
PRDM1
PR domain containing 1, with ZNF domain
chr1_-_68698197 0.41 ENST00000370973.2
ENST00000370971.1
WLS
wntless Wnt ligand secretion mediator
chr5_-_111091948 0.40 ENST00000447165.2
NREP
neuronal regeneration related protein
chr17_-_41738931 0.40 ENST00000329168.3
ENST00000549132.1
MEOX1
mesenchyme homeobox 1
chr6_+_28249299 0.39 ENST00000405948.2
PGBD1
piggyBac transposable element derived 1
chr6_+_28249332 0.39 ENST00000259883.3
PGBD1
piggyBac transposable element derived 1
chr7_+_134832808 0.39 ENST00000275767.3
TMEM140
transmembrane protein 140
chr6_-_42690312 0.39 ENST00000230381.5
PRPH2
peripherin 2 (retinal degeneration, slow)
chr19_+_13134772 0.37 ENST00000587760.1
ENST00000585575.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr9_+_2029019 0.37 ENST00000382194.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr20_-_30310797 0.37 ENST00000422920.1
BCL2L1
BCL2-like 1
chr10_-_29084886 0.36 ENST00000608061.1
ENST00000443246.2
ENST00000446012.1
LINC00837
long intergenic non-protein coding RNA 837
chr1_+_214163033 0.36 ENST00000607425.1
PROX1
prospero homeobox 1
chr3_+_141106458 0.36 ENST00000509883.1
ZBTB38
zinc finger and BTB domain containing 38
chr2_-_190445499 0.36 ENST00000261024.2
SLC40A1
solute carrier family 40 (iron-regulated transporter), member 1
chr12_-_71031185 0.36 ENST00000548122.1
ENST00000551525.1
ENST00000550358.1
PTPRB
protein tyrosine phosphatase, receptor type, B
chr12_-_91546926 0.35 ENST00000550758.1
DCN
decorin
chr1_-_44818599 0.34 ENST00000537474.1
ERI3
ERI1 exoribonuclease family member 3
chr3_+_52812523 0.34 ENST00000540715.1
ITIH1
inter-alpha-trypsin inhibitor heavy chain 1
chr20_+_62369623 0.34 ENST00000467211.1
RP4-583P15.14
RP4-583P15.14
chr9_-_16727978 0.33 ENST00000418777.1
ENST00000468187.2
BNC2
basonuclin 2
chr2_+_110656005 0.33 ENST00000437679.2
LIMS3
LIM and senescent cell antigen-like domains 3
chr3_-_112356944 0.32 ENST00000461431.1
CCDC80
coiled-coil domain containing 80
chr17_+_73975292 0.32 ENST00000397640.1
ENST00000416485.1
ENST00000588202.1
ENST00000590676.1
ENST00000586891.1
TEN1
TEN1 CST complex subunit
chr16_+_3068393 0.32 ENST00000573001.1
TNFRSF12A
tumor necrosis factor receptor superfamily, member 12A
chr12_+_40618873 0.32 ENST00000298910.7
LRRK2
leucine-rich repeat kinase 2
chr17_-_66951474 0.32 ENST00000269080.2
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr8_-_17942432 0.30 ENST00000381733.4
ENST00000314146.10
ASAH1
N-acylsphingosine amidohydrolase (acid ceramidase) 1
chr14_+_61654271 0.30 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
PRKCH
protein kinase C, eta
chr1_-_226924980 0.30 ENST00000272117.3
ITPKB
inositol-trisphosphate 3-kinase B
chr8_+_80523962 0.29 ENST00000518491.1
STMN2
stathmin-like 2
chr17_+_56315787 0.29 ENST00000262290.4
ENST00000421678.2
LPO
lactoperoxidase
chr22_+_25465786 0.29 ENST00000401395.1
KIAA1671
KIAA1671
chr12_-_54652060 0.28 ENST00000552562.1
CBX5
chromobox homolog 5
chr7_+_106809406 0.28 ENST00000468410.1
ENST00000478930.1
ENST00000464009.1
ENST00000222574.4
HBP1
HMG-box transcription factor 1
chr20_+_42574317 0.28 ENST00000358131.5
TOX2
TOX high mobility group box family member 2
chr3_+_52813932 0.27 ENST00000537050.1
ITIH1
inter-alpha-trypsin inhibitor heavy chain 1
chr17_-_3595181 0.27 ENST00000552050.1
P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chr2_+_135011731 0.26 ENST00000281923.2
MGAT5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr7_+_134671234 0.26 ENST00000436302.2
ENST00000359383.3
ENST00000458078.1
ENST00000435976.2
ENST00000455283.2
AGBL3
ATP/GTP binding protein-like 3
chr16_-_10652993 0.25 ENST00000536829.1
EMP2
epithelial membrane protein 2
chr17_-_73258425 0.25 ENST00000578348.1
ENST00000582486.1
ENST00000582717.1
GGA3
golgi-associated, gamma adaptin ear containing, ARF binding protein 3
chr5_+_140743859 0.25 ENST00000518069.1
PCDHGA5
protocadherin gamma subfamily A, 5
chr5_-_42811986 0.24 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
SEPP1
selenoprotein P, plasma, 1
chr22_-_30695471 0.24 ENST00000434291.1
RP1-130H16.18
Uncharacterized protein
chr2_-_231989808 0.24 ENST00000258400.3
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr11_-_8832182 0.24 ENST00000527510.1
ENST00000528527.1
ENST00000528523.1
ENST00000313726.6
ST5
suppression of tumorigenicity 5
chr16_+_56385290 0.24 ENST00000564727.1
GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chrX_+_150866779 0.24 ENST00000370353.3
PRRG3
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chr17_-_76220740 0.24 ENST00000600484.1
AC087645.1
Uncharacterized protein
chr1_+_154975258 0.23 ENST00000417934.2
ZBTB7B
zinc finger and BTB domain containing 7B
chrX_-_49041242 0.22 ENST00000453382.1
ENST00000540849.1
ENST00000536904.1
ENST00000432913.1
PRICKLE3
prickle homolog 3 (Drosophila)
chr19_+_11546153 0.22 ENST00000591946.1
ENST00000252455.2
ENST00000412601.1
PRKCSH
protein kinase C substrate 80K-H
chr17_+_45973516 0.22 ENST00000376741.4
SP2
Sp2 transcription factor
chr2_+_131369054 0.21 ENST00000409602.1
POTEJ
POTE ankyrin domain family, member J
chr2_+_145780725 0.21 ENST00000451478.1
TEX41
testis expressed 41 (non-protein coding)
chrX_-_128657457 0.21 ENST00000371121.3
ENST00000371123.1
ENST00000371122.4
SMARCA1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr19_+_11546093 0.21 ENST00000591462.1
PRKCSH
protein kinase C substrate 80K-H
chr1_-_103574024 0.21 ENST00000512756.1
ENST00000370096.3
ENST00000358392.2
ENST00000353414.4
COL11A1
collagen, type XI, alpha 1
chr16_-_89043377 0.21 ENST00000436887.2
ENST00000448839.1
ENST00000360302.2
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr12_-_71031220 0.21 ENST00000334414.6
PTPRB
protein tyrosine phosphatase, receptor type, B
chr6_-_41039567 0.21 ENST00000468811.1
OARD1
O-acyl-ADP-ribose deacylase 1
chr16_+_81272287 0.20 ENST00000425577.2
ENST00000564552.1
BCMO1
beta-carotene 15,15'-monooxygenase 1
chr5_-_140013275 0.20 ENST00000512545.1
ENST00000302014.6
ENST00000401743.2
CD14
CD14 molecule
chr6_-_46922659 0.20 ENST00000265417.7
GPR116
G protein-coupled receptor 116
chr7_-_38671098 0.20 ENST00000356264.2
AMPH
amphiphysin
chr7_-_38670957 0.20 ENST00000325590.5
ENST00000428293.2
AMPH
amphiphysin
chr12_-_50643664 0.19 ENST00000550592.1
LIMA1
LIM domain and actin binding 1
chr6_+_148663729 0.19 ENST00000367467.3
SASH1
SAM and SH3 domain containing 1
chr19_+_11546440 0.19 ENST00000589126.1
ENST00000588269.1
ENST00000587509.1
ENST00000592741.1
ENST00000593101.1
ENST00000587327.1
PRKCSH
protein kinase C substrate 80K-H
chr6_+_74405501 0.19 ENST00000437994.2
ENST00000422508.2
CD109
CD109 molecule
chr1_+_240408560 0.19 ENST00000441342.1
ENST00000545751.1
FMN2
formin 2
chr2_-_111291587 0.19 ENST00000437167.1
RGPD6
RANBP2-like and GRIP domain containing 6
chr7_+_80267973 0.18 ENST00000394788.3
ENST00000447544.2
CD36
CD36 molecule (thrombospondin receptor)
chr17_+_7533439 0.18 ENST00000441599.2
ENST00000380450.4
ENST00000416273.3
ENST00000575903.1
ENST00000576830.1
ENST00000571153.1
ENST00000575618.1
ENST00000576152.1
SHBG
sex hormone-binding globulin
chr2_+_109237717 0.18 ENST00000409441.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr2_-_183291741 0.18 ENST00000351439.5
ENST00000409365.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr1_+_185703513 0.18 ENST00000271588.4
ENST00000367492.2
HMCN1
hemicentin 1
chr20_-_30310336 0.18 ENST00000434194.1
ENST00000376062.2
BCL2L1
BCL2-like 1
chr20_+_43160458 0.18 ENST00000372889.1
ENST00000372887.1
ENST00000372882.3
PKIG
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr1_-_154150651 0.18 ENST00000302206.5
TPM3
tropomyosin 3
chr4_-_163085107 0.18 ENST00000379164.4
FSTL5
follistatin-like 5
chr4_+_3388057 0.18 ENST00000538395.1
RGS12
regulator of G-protein signaling 12
chr4_-_163085141 0.17 ENST00000427802.2
ENST00000306100.5
FSTL5
follistatin-like 5
chr17_-_26695013 0.17 ENST00000555059.2
CTB-96E2.2
Homeobox protein SEBOX
chr6_-_107077347 0.17 ENST00000369063.3
ENST00000539449.1
RTN4IP1
reticulon 4 interacting protein 1
chr12_+_56915713 0.17 ENST00000262031.5
ENST00000552247.2
RBMS2
RNA binding motif, single stranded interacting protein 2
chr12_-_91572278 0.17 ENST00000425043.1
ENST00000420120.2
ENST00000441303.2
ENST00000456569.2
DCN
decorin
chr15_+_83776137 0.17 ENST00000322019.9
TM6SF1
transmembrane 6 superfamily member 1
chr3_+_69915385 0.17 ENST00000314589.5
MITF
microphthalmia-associated transcription factor
chr20_-_30310693 0.17 ENST00000307677.4
ENST00000420653.1
BCL2L1
BCL2-like 1
chr19_+_39759154 0.17 ENST00000331982.5
IFNL2
interferon, lambda 2
chrX_-_65253506 0.16 ENST00000427538.1
VSIG4
V-set and immunoglobulin domain containing 4
chr12_+_56915776 0.16 ENST00000550726.1
ENST00000542360.1
RBMS2
RNA binding motif, single stranded interacting protein 2
chr1_-_27240455 0.16 ENST00000254227.3
NR0B2
nuclear receptor subfamily 0, group B, member 2
chrX_+_47444613 0.16 ENST00000445623.1
TIMP1
TIMP metallopeptidase inhibitor 1
chrX_-_65259900 0.16 ENST00000412866.2
VSIG4
V-set and immunoglobulin domain containing 4
chrX_-_65259914 0.16 ENST00000374737.4
ENST00000455586.2
VSIG4
V-set and immunoglobulin domain containing 4
chr10_+_114709999 0.16 ENST00000355995.4
ENST00000545257.1
ENST00000543371.1
ENST00000536810.1
ENST00000355717.4
ENST00000538897.1
ENST00000534894.1
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr3_-_18466787 0.15 ENST00000338745.6
ENST00000450898.1
SATB1
SATB homeobox 1
chr1_-_227505289 0.15 ENST00000366765.3
CDC42BPA
CDC42 binding protein kinase alpha (DMPK-like)
chr6_+_15246501 0.15 ENST00000341776.2
JARID2
jumonji, AT rich interactive domain 2
chr3_-_119396193 0.15 ENST00000484810.1
ENST00000497116.1
ENST00000261070.2
COX17
COX17 cytochrome c oxidase copper chaperone
chr2_-_183387064 0.15 ENST00000536095.1
ENST00000331935.6
ENST00000358139.2
ENST00000456212.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr4_-_141348999 0.15 ENST00000325617.5
CLGN
calmegin
chr6_+_33048222 0.15 ENST00000428835.1
HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chr3_+_141106643 0.15 ENST00000514251.1
ZBTB38
zinc finger and BTB domain containing 38
chr17_-_40833858 0.14 ENST00000332438.4
CCR10
chemokine (C-C motif) receptor 10
chr1_+_147374915 0.14 ENST00000240986.4
GJA8
gap junction protein, alpha 8, 50kDa
chr7_-_151217001 0.14 ENST00000262187.5
RHEB
Ras homolog enriched in brain
chr17_-_26694979 0.14 ENST00000438614.1
VTN
vitronectin
chr7_-_14026063 0.14 ENST00000443608.1
ENST00000438956.1
ETV1
ets variant 1
chr9_-_110251836 0.14 ENST00000374672.4
KLF4
Kruppel-like factor 4 (gut)
chr2_+_11679963 0.14 ENST00000263834.5
GREB1
growth regulation by estrogen in breast cancer 1
chr11_-_62783303 0.14 ENST00000336232.2
ENST00000430500.2
SLC22A8
solute carrier family 22 (organic anion transporter), member 8
chr3_-_101232019 0.14 ENST00000394095.2
ENST00000394091.1
ENST00000394094.2
ENST00000358203.3
ENST00000348610.3
ENST00000314261.7
SENP7
SUMO1/sentrin specific peptidase 7
chr5_-_55412774 0.13 ENST00000434982.2
ANKRD55
ankyrin repeat domain 55
chr5_-_127873896 0.13 ENST00000502468.1
FBN2
fibrillin 2
chr5_+_118965244 0.13 ENST00000515256.1
ENST00000509264.1
FAM170A
family with sequence similarity 170, member A
chr18_+_22040620 0.13 ENST00000426880.2
HRH4
histamine receptor H4
chr11_-_62783276 0.13 ENST00000535878.1
ENST00000545207.1
SLC22A8
solute carrier family 22 (organic anion transporter), member 8
chr1_+_152850787 0.13 ENST00000368765.3
SMCP
sperm mitochondria-associated cysteine-rich protein
chr16_-_69788816 0.13 ENST00000268802.5
NOB1
NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
chr4_-_46996424 0.12 ENST00000264318.3
GABRA4
gamma-aminobutyric acid (GABA) A receptor, alpha 4
chr12_+_6898638 0.12 ENST00000011653.4
CD4
CD4 molecule
chr16_-_3068171 0.12 ENST00000572154.1
ENST00000328796.4
CLDN6
claudin 6
chr3_-_139396787 0.12 ENST00000296202.7
ENST00000509291.1
NMNAT3
nicotinamide nucleotide adenylyltransferase 3
chr18_+_29027696 0.12 ENST00000257189.4
DSG3
desmoglein 3
chr7_-_5998714 0.12 ENST00000539903.1
RSPH10B
radial spoke head 10 homolog B (Chlamydomonas)
chr1_-_68698222 0.12 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
WLS
wntless Wnt ligand secretion mediator
chr17_+_29664830 0.12 ENST00000444181.2
ENST00000417592.2
NF1
neurofibromin 1
chr3_+_14989186 0.12 ENST00000435454.1
ENST00000323373.6
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr4_-_108641608 0.12 ENST00000265174.4
PAPSS1
3'-phosphoadenosine 5'-phosphosulfate synthase 1
chr4_-_40632605 0.12 ENST00000514014.1
RBM47
RNA binding motif protein 47
chr14_+_24407940 0.12 ENST00000354854.1
DHRS4-AS1
DHRS4-AS1
chr11_-_62476965 0.11 ENST00000405837.1
ENST00000531524.1
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr12_-_31479107 0.11 ENST00000542983.1
FAM60A
family with sequence similarity 60, member A
chr1_+_161677034 0.11 ENST00000349527.4
ENST00000309691.6
ENST00000294796.4
ENST00000367953.3
ENST00000367950.1
FCRLA
Fc receptor-like A
chr12_+_56624436 0.11 ENST00000266980.4
ENST00000437277.1
SLC39A5
solute carrier family 39 (zinc transporter), member 5
chr17_+_19186292 0.11 ENST00000395626.1
ENST00000571254.1
EPN2
epsin 2
chr3_+_69788576 0.11 ENST00000352241.4
ENST00000448226.2
MITF
microphthalmia-associated transcription factor
chr14_-_57277178 0.11 ENST00000339475.5
ENST00000554559.1
ENST00000555804.1
OTX2
orthodenticle homeobox 2
chr12_+_111471828 0.11 ENST00000261726.6
CUX2
cut-like homeobox 2
chr2_-_169887827 0.11 ENST00000263817.6
ABCB11
ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr19_+_35940486 0.11 ENST00000246549.2
FFAR2
free fatty acid receptor 2
chr13_-_95131923 0.11 ENST00000377028.5
ENST00000446125.1
DCT
dopachrome tautomerase
chrX_-_114253536 0.11 ENST00000371936.1
IL13RA2
interleukin 13 receptor, alpha 2
chr5_-_90679145 0.11 ENST00000265138.3
ARRDC3
arrestin domain containing 3
chr9_+_21409146 0.10 ENST00000380205.1
IFNA8
interferon, alpha 8
chr12_-_99548270 0.10 ENST00000546568.1
ENST00000332712.7
ENST00000546960.1
ANKS1B
ankyrin repeat and sterile alpha motif domain containing 1B
chr7_+_116312411 0.10 ENST00000456159.1
ENST00000397752.3
ENST00000318493.6
MET
met proto-oncogene
chr12_+_10366016 0.10 ENST00000546017.1
ENST00000535576.1
ENST00000539170.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr17_+_27895609 0.10 ENST00000581411.2
ENST00000301057.7
TP53I13
tumor protein p53 inducible protein 13
chr1_+_248201474 0.10 ENST00000366479.2
OR2L2
olfactory receptor, family 2, subfamily L, member 2
chr15_-_28778117 0.10 ENST00000525590.2
ENST00000329523.6
GOLGA8G
golgin A8 family, member G
chr1_-_166944561 0.10 ENST00000271417.3
ILDR2
immunoglobulin-like domain containing receptor 2
chr7_-_107443652 0.10 ENST00000340010.5
ENST00000422236.2
ENST00000453332.1
SLC26A3
solute carrier family 26 (anion exchanger), member 3
chr12_-_99548645 0.10 ENST00000549025.2
ANKS1B
ankyrin repeat and sterile alpha motif domain containing 1B
chr1_+_40420802 0.09 ENST00000372811.5
ENST00000420632.2
ENST00000434861.1
ENST00000372809.5
MFSD2A
major facilitator superfamily domain containing 2A
chr5_+_75699040 0.09 ENST00000274364.6
IQGAP2
IQ motif containing GTPase activating protein 2
chr19_-_39735646 0.09 ENST00000413851.2
IFNL3
interferon, lambda 3
chr14_+_69865401 0.09 ENST00000556605.1
ENST00000336643.5
ENST00000031146.4
SLC39A9
solute carrier family 39, member 9
chr5_-_158757895 0.09 ENST00000231228.2
IL12B
interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
chr14_+_62585332 0.09 ENST00000554895.1
LINC00643
long intergenic non-protein coding RNA 643
chr8_+_9953061 0.09 ENST00000522907.1
ENST00000528246.1
MSRA
methionine sulfoxide reductase A
chr1_-_155947951 0.09 ENST00000313695.7
ENST00000497907.1
ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr12_-_58135903 0.09 ENST00000257897.3
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr5_+_56471592 0.09 ENST00000511209.1
GPBP1
GC-rich promoter binding protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of NR2E1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0090427 activation of meiosis(GO:0090427)
0.5 2.0 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.4 1.3 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.2 0.6 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.2 1.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.1 0.5 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.1 GO:0071350 interleukin-15-mediated signaling pathway(GO:0035723) cellular response to interleukin-15(GO:0071350)
0.1 0.4 GO:0043049 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.1 0.4 GO:0070839 divalent metal ion export(GO:0070839)
0.1 1.8 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
0.1 0.5 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 0.8 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.1 0.5 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.1 2.3 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 0.5 GO:0001827 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.1 0.7 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.1 0.4 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.1 0.4 GO:0061056 sclerotome development(GO:0061056)
0.1 1.1 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.3 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.1 0.6 GO:1904996 PML body organization(GO:0030578) positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.1 0.2 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.1 0.6 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 1.7 GO:0043586 tongue development(GO:0043586)
0.1 0.3 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.2 GO:0071727 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.0 0.2 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.1 GO:1904798 negative regulation of muscle hyperplasia(GO:0014740) positive regulation of core promoter binding(GO:1904798)
0.0 0.3 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.1 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 0.2 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.3 GO:0035726 regulation of neutrophil apoptotic process(GO:0033029) common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.3 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.1 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.0 0.2 GO:0035989 tendon development(GO:0035989)
0.0 1.0 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.2 GO:0071726 toll-like receptor TLR6:TLR2 signaling pathway(GO:0038124) response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0 0.3 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0 0.2 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.1 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.3 GO:0070836 caveola assembly(GO:0070836)
0.0 0.1 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.1 GO:1900158 positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.0 0.1 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.0 0.1 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.2 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.3 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.5 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.0 0.6 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.2 GO:0021615 rhombomere development(GO:0021546) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.0 0.2 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.1 GO:0018874 benzoate metabolic process(GO:0018874)
0.0 0.1 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.1 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.0 0.1 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.0 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.0 0.1 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 0.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.5 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 0.0 GO:0042040 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.0 0.1 GO:0019087 transformation of host cell by virus(GO:0019087)
0.0 0.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.2 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0051142 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.1 GO:2001023 regulation of response to drug(GO:2001023)
0.0 0.1 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 0.0 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.0 0.1 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 1.0 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.0 GO:0060161 positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.0 0.4 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.1 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
0.0 0.1 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.0 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.0 0.0 GO:1900378 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.2 0.6 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 0.3 GO:0044753 amphisome(GO:0044753)
0.1 0.7 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.7 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.5 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.2 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 1.1 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 2.5 GO:0005901 caveola(GO:0005901)
0.0 0.1 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.0 0.6 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 1.1 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.3 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.4 GO:0071564 npBAF complex(GO:0071564)
0.0 0.2 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.0 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.3 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.2 1.3 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 2.2 GO:0033691 sialic acid binding(GO:0033691)
0.1 2.0 GO:0003680 AT DNA binding(GO:0003680)
0.1 1.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.5 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1 0.7 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.3 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.3 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 0.8 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.1 0.5 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.3 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.0 0.3 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.3 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.4 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.4 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.2 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.0 0.1 GO:0004779 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.0 0.3 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.3 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.1 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.2 GO:0005497 androgen binding(GO:0005497)
0.0 0.1 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.3 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.3 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 0.1 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.2 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.6 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 1.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.4 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.0 GO:0061598 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292) hyaluronoglucuronidase activity(GO:0033906)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.0 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.0 1.4 GO:0002039 p53 binding(GO:0002039)
0.0 0.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 3.7 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 2.8 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.1 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 0.6 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.5 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.0 PID MTOR 4PATHWAY mTOR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.1 2.0 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.6 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.5 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.8 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 1.4 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.7 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.8 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.2 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.5 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.3 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.1 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation