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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for NR4A1

Z-value: 0.59

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Transcription factors associated with NR4A1

Gene Symbol Gene ID Gene Info
NR4A1
ENSG00000123358.15 nuclear receptor subfamily 4 group A member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR4A1hg19_v2_chr12_+_52445191_524452430.518.8e-03Click!

Activity profile of NR4A1 motif

Sorted Z-values of NR4A1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_228678550 1.57 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr1_+_61869748 0.98 ENST00000357977.5
NFIA
nuclear factor I/A
chr5_+_159895275 0.91 ENST00000517927.1
MIR146A
microRNA 146a
chr12_-_109219937 0.86 ENST00000546697.1
SSH1
slingshot protein phosphatase 1
chr6_+_108616054 0.81 ENST00000368977.4
LACE1
lactation elevated 1
chr22_+_24891210 0.80 ENST00000382760.2
UPB1
ureidopropionase, beta
chr10_-_33625154 0.77 ENST00000265371.4
NRP1
neuropilin 1
chr11_+_86748863 0.59 ENST00000340353.7
TMEM135
transmembrane protein 135
chr12_+_93963590 0.58 ENST00000340600.2
SOCS2
suppressor of cytokine signaling 2
chr6_+_108616243 0.57 ENST00000421954.1
LACE1
lactation elevated 1
chr20_+_31755934 0.54 ENST00000354932.5
BPIFA2
BPI fold containing family A, member 2
chr12_+_32655110 0.52 ENST00000546442.1
ENST00000583694.1
FGD4
FYVE, RhoGEF and PH domain containing 4
chr2_+_162016827 0.52 ENST00000429217.1
ENST00000406287.1
ENST00000402568.1
TANK
TRAF family member-associated NFKB activator
chr10_+_35484793 0.50 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
CREM
cAMP responsive element modulator
chr16_+_81272287 0.49 ENST00000425577.2
ENST00000564552.1
BCMO1
beta-carotene 15,15'-monooxygenase 1
chr1_+_212738676 0.44 ENST00000366981.4
ENST00000366987.2
ATF3
activating transcription factor 3
chr2_+_162016804 0.40 ENST00000392749.2
ENST00000440506.1
TANK
TRAF family member-associated NFKB activator
chr2_+_162016916 0.40 ENST00000405852.1
TANK
TRAF family member-associated NFKB activator
chr3_-_138763734 0.38 ENST00000413199.1
ENST00000502927.2
PRR23C
proline rich 23C
chr19_+_4153598 0.38 ENST00000078445.2
ENST00000252587.3
ENST00000595923.1
ENST00000602257.1
ENST00000602147.1
CREB3L3
cAMP responsive element binding protein 3-like 3
chr19_+_49713991 0.37 ENST00000597316.1
TRPM4
transient receptor potential cation channel, subfamily M, member 4
chr4_-_159080806 0.37 ENST00000590648.1
FAM198B
family with sequence similarity 198, member B
chr11_+_3876859 0.37 ENST00000300737.4
STIM1
stromal interaction molecule 1
chr5_+_73109339 0.36 ENST00000296799.4
ARHGEF28
Rho guanine nucleotide exchange factor (GEF) 28
chr6_+_44126545 0.36 ENST00000532171.1
ENST00000398776.1
ENST00000542245.1
CAPN11
calpain 11
chr19_+_13134772 0.36 ENST00000587760.1
ENST00000585575.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr11_+_7618413 0.36 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr4_-_89744314 0.35 ENST00000508369.1
FAM13A
family with sequence similarity 13, member A
chr17_-_66287310 0.32 ENST00000582867.1
SLC16A6
solute carrier family 16, member 6
chr9_-_75567962 0.32 ENST00000297785.3
ENST00000376939.1
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr11_-_113577052 0.31 ENST00000540540.1
ENST00000545579.1
ENST00000538955.1
ENST00000299882.5
TMPRSS5
transmembrane protease, serine 5
chr2_-_178257401 0.30 ENST00000464747.1
NFE2L2
nuclear factor, erythroid 2-like 2
chr11_+_66624527 0.29 ENST00000393952.3
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr7_-_37488834 0.28 ENST00000310758.4
ELMO1
engulfment and cell motility 1
chr17_+_1646130 0.27 ENST00000453066.1
ENST00000324015.3
ENST00000450523.2
ENST00000453723.1
ENST00000382061.4
SERPINF2
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr1_+_64059332 0.27 ENST00000540265.1
PGM1
phosphoglucomutase 1
chr9_+_12693336 0.26 ENST00000381137.2
ENST00000388918.5
TYRP1
tyrosinase-related protein 1
chr2_+_178257372 0.25 ENST00000264167.4
ENST00000409888.1
AGPS
alkylglycerone phosphate synthase
chr3_-_30936153 0.23 ENST00000454381.3
ENST00000282538.5
GADL1
glutamate decarboxylase-like 1
chr18_-_52969844 0.21 ENST00000561831.3
TCF4
transcription factor 4
chr12_+_32655048 0.21 ENST00000427716.2
ENST00000266482.3
FGD4
FYVE, RhoGEF and PH domain containing 4
chr4_-_40632605 0.21 ENST00000514014.1
RBM47
RNA binding motif protein 47
chr4_+_159593271 0.21 ENST00000512251.1
ENST00000511912.1
ETFDH
electron-transferring-flavoprotein dehydrogenase
chr19_+_54926621 0.20 ENST00000376530.3
ENST00000445095.1
ENST00000391739.3
ENST00000376531.3
TTYH1
tweety family member 1
chr17_-_66287257 0.20 ENST00000327268.4
SLC16A6
solute carrier family 16, member 6
chr11_-_113577014 0.20 ENST00000544634.1
ENST00000539732.1
ENST00000538770.1
ENST00000536856.1
ENST00000544476.1
TMPRSS5
transmembrane protease, serine 5
chr19_+_54926601 0.20 ENST00000301194.4
TTYH1
tweety family member 1
chr11_+_278365 0.20 ENST00000534750.1
NLRP6
NLR family, pyrin domain containing 6
chr6_-_33771757 0.20 ENST00000507738.1
ENST00000266003.5
ENST00000430124.2
MLN
motilin
chr13_-_33112823 0.20 ENST00000504114.1
N4BP2L2
NEDD4 binding protein 2-like 2
chr19_-_11639931 0.19 ENST00000592312.1
ENST00000590480.1
ENST00000585318.1
ENST00000252440.7
ENST00000417981.2
ENST00000270517.7
ECSIT
ECSIT signalling integrator
chr3_-_133648656 0.19 ENST00000408895.2
C3orf36
chromosome 3 open reading frame 36
chr10_-_103815874 0.19 ENST00000370033.4
ENST00000311122.5
C10orf76
chromosome 10 open reading frame 76
chr19_-_11639910 0.18 ENST00000588998.1
ENST00000586149.1
ECSIT
ECSIT signalling integrator
chr10_-_17171817 0.17 ENST00000377833.4
CUBN
cubilin (intrinsic factor-cobalamin receptor)
chr4_-_89744365 0.17 ENST00000513837.1
ENST00000503556.1
FAM13A
family with sequence similarity 13, member A
chr3_+_184055240 0.16 ENST00000383847.2
FAM131A
family with sequence similarity 131, member A
chr7_-_99774945 0.15 ENST00000292377.2
GPC2
glypican 2
chr19_+_11546093 0.15 ENST00000591462.1
PRKCSH
protein kinase C substrate 80K-H
chr4_-_89744457 0.15 ENST00000395002.2
FAM13A
family with sequence similarity 13, member A
chr17_-_2169425 0.15 ENST00000570606.1
ENST00000354901.4
SMG6
SMG6 nonsense mediated mRNA decay factor
chr19_+_11546440 0.14 ENST00000589126.1
ENST00000588269.1
ENST00000587509.1
ENST00000592741.1
ENST00000593101.1
ENST00000587327.1
PRKCSH
protein kinase C substrate 80K-H
chr1_+_176432298 0.14 ENST00000367661.3
ENST00000367662.3
PAPPA2
pappalysin 2
chr10_+_104005272 0.14 ENST00000369983.3
GBF1
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr19_+_11546153 0.14 ENST00000591946.1
ENST00000252455.2
ENST00000412601.1
PRKCSH
protein kinase C substrate 80K-H
chr8_+_99956759 0.13 ENST00000522510.1
ENST00000457907.2
OSR2
odd-skipped related transciption factor 2
chr7_-_107443652 0.13 ENST00000340010.5
ENST00000422236.2
ENST00000453332.1
SLC26A3
solute carrier family 26 (anion exchanger), member 3
chr22_-_31364187 0.13 ENST00000215862.4
ENST00000397641.3
MORC2
MORC family CW-type zinc finger 2
chr6_+_31895254 0.12 ENST00000299367.5
ENST00000442278.2
C2
complement component 2
chr1_-_161102421 0.12 ENST00000490843.2
ENST00000368006.3
ENST00000392188.1
ENST00000545495.1
DEDD
death effector domain containing
chr11_+_86748998 0.12 ENST00000525018.1
ENST00000355734.4
TMEM135
transmembrane protein 135
chr19_+_17416457 0.12 ENST00000252602.1
MRPL34
mitochondrial ribosomal protein L34
chr19_+_17416609 0.12 ENST00000602206.1
MRPL34
mitochondrial ribosomal protein L34
chr11_+_116700600 0.12 ENST00000227667.3
APOC3
apolipoprotein C-III
chr14_-_104387831 0.12 ENST00000557040.1
ENST00000414262.2
ENST00000555030.1
ENST00000554713.1
ENST00000553430.1
C14orf2
chromosome 14 open reading frame 2
chr1_-_161102367 0.11 ENST00000464113.1
DEDD
death effector domain containing
chr11_+_116700614 0.11 ENST00000375345.1
APOC3
apolipoprotein C-III
chr14_-_77495007 0.11 ENST00000238647.3
IRF2BPL
interferon regulatory factor 2 binding protein-like
chr6_+_118869452 0.11 ENST00000357525.5
PLN
phospholamban
chr14_-_104387888 0.10 ENST00000286953.3
C14orf2
chromosome 14 open reading frame 2
chr11_+_64073699 0.10 ENST00000405666.1
ENST00000468670.1
ESRRA
estrogen-related receptor alpha
chr10_-_75634326 0.10 ENST00000322635.3
ENST00000444854.2
ENST00000423381.1
ENST00000322680.3
ENST00000394762.2
CAMK2G
calcium/calmodulin-dependent protein kinase II gamma
chr19_-_41256207 0.10 ENST00000598485.2
ENST00000470681.1
ENST00000339153.3
ENST00000598729.1
C19orf54
chromosome 19 open reading frame 54
chr22_-_51016846 0.10 ENST00000312108.7
ENST00000395650.2
CPT1B
carnitine palmitoyltransferase 1B (muscle)
chr3_+_184037466 0.10 ENST00000441154.1
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr8_-_70016408 0.10 ENST00000518540.1
RP11-600K15.1
RP11-600K15.1
chr8_-_92053212 0.09 ENST00000285419.3
TMEM55A
transmembrane protein 55A
chr1_+_2398876 0.09 ENST00000449969.1
PLCH2
phospholipase C, eta 2
chr3_-_44519131 0.09 ENST00000425708.2
ENST00000396077.2
ZNF445
zinc finger protein 445
chr1_+_40713573 0.09 ENST00000372766.3
TMCO2
transmembrane and coiled-coil domains 2
chrX_+_135618258 0.09 ENST00000440515.1
ENST00000456412.1
VGLL1
vestigial like 1 (Drosophila)
chr10_-_74714533 0.08 ENST00000373032.3
PLA2G12B
phospholipase A2, group XIIB
chr8_+_99956662 0.08 ENST00000523368.1
ENST00000297565.4
ENST00000435298.2
OSR2
odd-skipped related transciption factor 2
chr20_+_11898507 0.08 ENST00000378226.2
BTBD3
BTB (POZ) domain containing 3
chrX_+_2746818 0.08 ENST00000398806.3
GYG2
glycogenin 2
chr10_-_75634260 0.08 ENST00000372765.1
ENST00000351293.3
CAMK2G
calcium/calmodulin-dependent protein kinase II gamma
chrX_+_2746850 0.08 ENST00000381163.3
ENST00000338623.5
ENST00000542787.1
GYG2
glycogenin 2
chr1_-_33815486 0.07 ENST00000373418.3
PHC2
polyhomeotic homolog 2 (Drosophila)
chr17_+_73629500 0.07 ENST00000375215.3
SMIM5
small integral membrane protein 5
chr7_-_105517021 0.07 ENST00000318724.4
ENST00000419735.3
ATXN7L1
ataxin 7-like 1
chr6_+_64346386 0.07 ENST00000509330.1
PHF3
PHD finger protein 3
chr3_+_63638339 0.07 ENST00000343837.3
ENST00000469440.1
SNTN
sentan, cilia apical structure protein
chr7_-_105516923 0.07 ENST00000478915.1
ATXN7L1
ataxin 7-like 1
chr2_+_207024306 0.07 ENST00000236957.5
ENST00000392221.1
ENST00000392222.2
ENST00000445505.1
EEF1B2
eukaryotic translation elongation factor 1 beta 2
chr7_-_6048650 0.07 ENST00000382321.4
ENST00000406569.3
PMS2
PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
chr18_-_60986613 0.07 ENST00000444484.1
BCL2
B-cell CLL/lymphoma 2
chr13_-_33112899 0.07 ENST00000267068.3
ENST00000357505.6
ENST00000399396.3
N4BP2L2
NEDD4 binding protein 2-like 2
chr3_-_48936272 0.07 ENST00000544097.1
ENST00000430379.1
ENST00000319017.4
SLC25A20
solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
chr20_+_12989596 0.06 ENST00000434210.1
ENST00000399002.2
SPTLC3
serine palmitoyltransferase, long chain base subunit 3
chr7_+_99933730 0.06 ENST00000610247.1
PILRB
paired immunoglobin-like type 2 receptor beta
chr17_+_4854375 0.06 ENST00000521811.1
ENST00000519602.1
ENST00000323997.6
ENST00000522249.1
ENST00000519584.1
ENO3
enolase 3 (beta, muscle)
chr7_-_72936531 0.06 ENST00000339594.4
BAZ1B
bromodomain adjacent to zinc finger domain, 1B
chr22_-_51017084 0.06 ENST00000360719.2
ENST00000457250.1
ENST00000440709.1
CPT1B
carnitine palmitoyltransferase 1B (muscle)
chr3_+_14989186 0.06 ENST00000435454.1
ENST00000323373.6
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr7_+_119913688 0.05 ENST00000331113.4
KCND2
potassium voltage-gated channel, Shal-related subfamily, member 2
chr18_-_24722995 0.05 ENST00000581714.1
CHST9
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr12_+_109577202 0.05 ENST00000377848.3
ENST00000377854.5
ACACB
acetyl-CoA carboxylase beta
chr6_+_36973406 0.05 ENST00000274963.8
FGD2
FYVE, RhoGEF and PH domain containing 2
chr3_+_14989076 0.05 ENST00000413118.1
ENST00000425241.1
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr3_+_184038073 0.05 ENST00000428387.1
ENST00000434061.2
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr10_+_101542462 0.05 ENST00000370449.4
ENST00000370434.1
ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr7_-_6048702 0.05 ENST00000265849.7
PMS2
PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
chr4_+_176986978 0.05 ENST00000508596.1
ENST00000393643.2
WDR17
WD repeat domain 17
chr6_+_30594619 0.05 ENST00000318999.7
ENST00000376485.4
ENST00000376478.2
ENST00000319027.5
ENST00000376483.4
ENST00000329992.8
ENST00000330083.5
ATAT1
alpha tubulin acetyltransferase 1
chr14_+_35591735 0.05 ENST00000604948.1
ENST00000605201.1
ENST00000250377.7
ENST00000321130.10
ENST00000534898.4
KIAA0391
KIAA0391
chr12_+_58335360 0.04 ENST00000300145.3
XRCC6BP1
XRCC6 binding protein 1
chr10_-_128359074 0.04 ENST00000544758.1
C10orf90
chromosome 10 open reading frame 90
chr12_-_53320245 0.04 ENST00000552150.1
KRT8
keratin 8
chr1_-_197036364 0.04 ENST00000367412.1
F13B
coagulation factor XIII, B polypeptide
chr13_-_33112956 0.04 ENST00000505213.1
N4BP2L2
NEDD4 binding protein 2-like 2
chr3_+_51741072 0.03 ENST00000395052.3
GRM2
glutamate receptor, metabotropic 2
chr14_+_22386325 0.03 ENST00000390439.2
TRAV13-2
T cell receptor alpha variable 13-2
chr17_+_48423453 0.03 ENST00000017003.2
ENST00000509778.1
ENST00000507602.1
XYLT2
xylosyltransferase II
chr7_-_81399355 0.02 ENST00000457544.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr17_-_7307358 0.02 ENST00000576017.1
ENST00000302422.3
ENST00000535512.1
TMEM256
TMEM256-PLSCR3
transmembrane protein 256
TMEM256-PLSCR3 readthrough (NMD candidate)
chr4_-_111563076 0.02 ENST00000354925.2
ENST00000511990.1
PITX2
paired-like homeodomain 2
chr12_+_49687425 0.02 ENST00000257860.4
PRPH
peripherin
chr14_-_24711470 0.02 ENST00000559969.1
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr20_+_3052264 0.02 ENST00000217386.2
OXT
oxytocin/neurophysin I prepropeptide
chr10_+_12110963 0.01 ENST00000263035.4
ENST00000437298.1
DHTKD1
dehydrogenase E1 and transketolase domain containing 1
chr8_-_120685608 0.01 ENST00000427067.2
ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr12_+_6644443 0.01 ENST00000396858.1
GAPDH
glyceraldehyde-3-phosphate dehydrogenase
chr20_+_17680599 0.01 ENST00000246090.5
BANF2
barrier to autointegration factor 2
chr2_+_234216454 0.00 ENST00000447536.1
ENST00000409110.1
SAG
S-antigen; retina and pineal gland (arrestin)
chr4_-_65275162 0.00 ENST00000381210.3
ENST00000507440.1
TECRL
trans-2,3-enoyl-CoA reductase-like
chr17_+_41150290 0.00 ENST00000589037.1
ENST00000253788.5
RPL27
ribosomal protein L27
chr17_+_41150479 0.00 ENST00000589913.1
RPL27
ribosomal protein L27

Network of associatons between targets according to the STRING database.

First level regulatory network of NR4A1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.3 0.9 GO:1904719 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.2 1.3 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.2 0.7 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.2 0.8 GO:0060301 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.1 0.4 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.4 GO:1990736 positive regulation of regulation of vascular smooth muscle cell membrane depolarization(GO:1904199) regulation of vascular smooth muscle cell membrane depolarization(GO:1990736)
0.1 0.3 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 0.2 GO:2000910 negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910)
0.1 0.6 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.1 0.4 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.3 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.2 GO:0036023 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.0 0.3 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 1.0 GO:0072189 ureter development(GO:0072189)
0.0 0.1 GO:1901876 regulation of the force of heart contraction by cardiac conduction(GO:0086092) regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.0 0.1 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.4 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.6 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.3 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0 0.1 GO:1902616 acyl carnitine transport(GO:0006844) acyl carnitine transmembrane transport(GO:1902616)
0.0 0.2 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.3 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.1 GO:0016999 antibiotic metabolic process(GO:0016999) detoxification of mercury ion(GO:0050787)
0.0 0.7 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.4 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.1 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 0.2 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.1 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 1.2 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.1 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 0.8 GO:0097443 sorting endosome(GO:0097443)
0.0 0.4 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.4 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.2 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.4 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.3 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.2 1.3 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.6 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 0.8 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 0.2 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.4 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.3 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1 0.2 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.1 0.2 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.0 0.2 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.0 0.3 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 0.1 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.0 0.2 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.1 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.0 0.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.5 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.9 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.0 PID HNF3A PATHWAY FOXA1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.8 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.4 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 1.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.6 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.4 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.5 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D