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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for NR4A2

Z-value: 0.56

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Transcription factors associated with NR4A2

Gene Symbol Gene ID Gene Info
NR4A2
ENSG00000153234.9 nuclear receptor subfamily 4 group A member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR4A2hg19_v2_chr2_-_157189180_1571892900.058.1e-01Click!

Activity profile of NR4A2 motif

Sorted Z-values of NR4A2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_228678550 3.11 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr10_+_81107271 1.08 ENST00000448165.1
PPIF
peptidylprolyl isomerase F
chr14_-_55369525 1.03 ENST00000543643.2
ENST00000536224.2
ENST00000395514.1
ENST00000491895.2
GCH1
GTP cyclohydrolase 1
chr1_+_212738676 0.91 ENST00000366981.4
ENST00000366987.2
ATF3
activating transcription factor 3
chr19_+_45251804 0.88 ENST00000164227.5
BCL3
B-cell CLL/lymphoma 3
chr13_+_97928395 0.85 ENST00000445661.2
MBNL2
muscleblind-like splicing regulator 2
chr2_+_162016827 0.78 ENST00000429217.1
ENST00000406287.1
ENST00000402568.1
TANK
TRAF family member-associated NFKB activator
chr4_-_139163491 0.71 ENST00000280612.5
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr9_-_136344237 0.69 ENST00000432868.1
ENST00000371899.4
SLC2A6
solute carrier family 2 (facilitated glucose transporter), member 6
chr12_-_120554534 0.64 ENST00000538903.1
ENST00000534951.1
RAB35
RAB35, member RAS oncogene family
chr15_-_55562582 0.61 ENST00000396307.2
RAB27A
RAB27A, member RAS oncogene family
chr2_+_11817713 0.58 ENST00000449576.2
LPIN1
lipin 1
chr2_+_162016804 0.57 ENST00000392749.2
ENST00000440506.1
TANK
TRAF family member-associated NFKB activator
chr1_+_169075554 0.57 ENST00000367815.4
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr15_-_55562479 0.54 ENST00000564609.1
RAB27A
RAB27A, member RAS oncogene family
chr9_-_136344197 0.52 ENST00000414172.1
ENST00000371897.4
SLC2A6
solute carrier family 2 (facilitated glucose transporter), member 6
chr7_+_112090483 0.50 ENST00000403825.3
ENST00000429071.1
IFRD1
interferon-related developmental regulator 1
chr2_+_162016916 0.47 ENST00000405852.1
TANK
TRAF family member-associated NFKB activator
chr20_+_37590942 0.46 ENST00000373325.2
ENST00000252011.3
ENST00000373323.4
DHX35
DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr5_-_131347501 0.45 ENST00000543479.1
ACSL6
acyl-CoA synthetase long-chain family member 6
chr11_-_47470591 0.45 ENST00000524487.1
RAPSN
receptor-associated protein of the synapse
chr8_+_21911054 0.45 ENST00000519850.1
ENST00000381470.3
DMTN
dematin actin binding protein
chr7_+_128399002 0.44 ENST00000493278.1
CALU
calumenin
chr8_+_145149930 0.43 ENST00000318911.4
CYC1
cytochrome c-1
chr10_+_81107216 0.42 ENST00000394579.3
ENST00000225174.3
PPIF
peptidylprolyl isomerase F
chr12_-_46121554 0.41 ENST00000609803.1
LINC00938
long intergenic non-protein coding RNA 938
chr13_+_102142296 0.41 ENST00000376162.3
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr19_+_1407733 0.38 ENST00000592453.1
DAZAP1
DAZ associated protein 1
chr3_-_113464906 0.37 ENST00000477813.1
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr6_-_34664612 0.37 ENST00000374023.3
ENST00000374026.3
C6orf106
chromosome 6 open reading frame 106
chr22_+_30792980 0.37 ENST00000403484.1
ENST00000405717.3
ENST00000402592.3
SEC14L2
SEC14-like 2 (S. cerevisiae)
chr1_-_27816556 0.36 ENST00000536657.1
WASF2
WAS protein family, member 2
chr1_-_157108266 0.35 ENST00000326786.4
ETV3
ets variant 3
chr8_+_134125727 0.35 ENST00000521107.1
TG
thyroglobulin
chr3_+_113465866 0.35 ENST00000273398.3
ENST00000538620.1
ENST00000496747.1
ENST00000475322.1
ATP6V1A
ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr5_+_66124590 0.35 ENST00000490016.2
ENST00000403666.1
ENST00000450827.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr11_+_67007518 0.34 ENST00000530342.1
ENST00000308783.5
KDM2A
lysine (K)-specific demethylase 2A
chr1_+_206858328 0.34 ENST00000367103.3
MAPKAPK2
mitogen-activated protein kinase-activated protein kinase 2
chr15_+_59730348 0.33 ENST00000288228.5
ENST00000559628.1
ENST00000557914.1
ENST00000560474.1
FAM81A
family with sequence similarity 81, member A
chrX_-_150067069 0.32 ENST00000466436.1
CD99L2
CD99 molecule-like 2
chr11_-_47470703 0.31 ENST00000298854.2
RAPSN
receptor-associated protein of the synapse
chr1_+_206858232 0.30 ENST00000294981.4
MAPKAPK2
mitogen-activated protein kinase-activated protein kinase 2
chr16_+_85942594 0.30 ENST00000566369.1
IRF8
interferon regulatory factor 8
chr17_+_7533439 0.30 ENST00000441599.2
ENST00000380450.4
ENST00000416273.3
ENST00000575903.1
ENST00000576830.1
ENST00000571153.1
ENST00000575618.1
ENST00000576152.1
SHBG
sex hormone-binding globulin
chr12_+_120875910 0.30 ENST00000551806.1
AL021546.6
Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial
chr12_-_81992111 0.29 ENST00000443686.3
ENST00000407050.4
PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr14_+_23791159 0.28 ENST00000557702.1
PABPN1
poly(A) binding protein, nuclear 1
chr20_+_43343886 0.27 ENST00000190983.4
WISP2
WNT1 inducible signaling pathway protein 2
chr14_+_21498666 0.27 ENST00000481535.1
TPPP2
tubulin polymerization-promoting protein family member 2
chr20_-_48532019 0.27 ENST00000289431.5
SPATA2
spermatogenesis associated 2
chr6_-_39290316 0.27 ENST00000425054.2
ENST00000373227.4
ENST00000373229.5
ENST00000437525.2
KCNK16
potassium channel, subfamily K, member 16
chr19_+_6739662 0.24 ENST00000313285.8
ENST00000313244.9
ENST00000596758.1
TRIP10
thyroid hormone receptor interactor 10
chr10_+_51371390 0.24 ENST00000478381.1
ENST00000451577.2
ENST00000374098.2
ENST00000374097.2
TIMM23B
translocase of inner mitochondrial membrane 23 homolog B (yeast)
chr11_-_47470682 0.24 ENST00000529341.1
ENST00000352508.3
RAPSN
receptor-associated protein of the synapse
chr17_-_27503770 0.24 ENST00000533112.1
MYO18A
myosin XVIIIA
chr12_-_108954933 0.24 ENST00000431469.2
ENST00000546815.1
SART3
squamous cell carcinoma antigen recognized by T cells 3
chr22_+_30821732 0.23 ENST00000355143.4
MTFP1
mitochondrial fission process 1
chr10_-_50970322 0.23 ENST00000374103.4
OGDHL
oxoglutarate dehydrogenase-like
chr3_+_129247479 0.23 ENST00000296271.3
RHO
rhodopsin
chr15_-_41408339 0.23 ENST00000401393.3
INO80
INO80 complex subunit
chr19_+_46850251 0.23 ENST00000012443.4
PPP5C
protein phosphatase 5, catalytic subunit
chr19_+_45394477 0.23 ENST00000252487.5
ENST00000405636.2
ENST00000592434.1
ENST00000426677.2
ENST00000589649.1
TOMM40
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr10_-_50970382 0.23 ENST00000419399.1
ENST00000432695.1
OGDHL
oxoglutarate dehydrogenase-like
chr20_+_31755934 0.22 ENST00000354932.5
BPIFA2
BPI fold containing family A, member 2
chr16_+_4674787 0.22 ENST00000262370.7
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr5_-_131347583 0.22 ENST00000379255.1
ENST00000430403.1
ENST00000544770.1
ENST00000379246.1
ENST00000414078.1
ENST00000441995.1
ACSL6
acyl-CoA synthetase long-chain family member 6
chr17_+_73975292 0.22 ENST00000397640.1
ENST00000416485.1
ENST00000588202.1
ENST00000590676.1
ENST00000586891.1
TEN1
TEN1 CST complex subunit
chr19_-_4535233 0.21 ENST00000381848.3
ENST00000588887.1
ENST00000586133.1
PLIN5
perilipin 5
chr1_+_155583012 0.21 ENST00000462250.2
MSTO1
misato 1, mitochondrial distribution and morphology regulator
chr1_-_1711508 0.21 ENST00000378625.1
NADK
NAD kinase
chr22_+_18121356 0.20 ENST00000317582.5
ENST00000543133.1
ENST00000538149.1
ENST00000337612.5
ENST00000493680.1
BCL2L13
BCL2-like 13 (apoptosis facilitator)
chr19_+_42824511 0.20 ENST00000601644.1
TMEM145
transmembrane protein 145
chr1_-_8877692 0.20 ENST00000400908.2
RERE
arginine-glutamic acid dipeptide (RE) repeats
chr9_-_39239171 0.20 ENST00000358144.2
CNTNAP3
contactin associated protein-like 3
chr22_-_39239987 0.20 ENST00000333039.2
NPTXR
neuronal pentraxin receptor
chr3_+_14989186 0.19 ENST00000435454.1
ENST00000323373.6
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr19_+_3880581 0.19 ENST00000450849.2
ENST00000301260.6
ENST00000398448.3
ATCAY
ataxia, cerebellar, Cayman type
chrX_+_135230712 0.19 ENST00000535737.1
FHL1
four and a half LIM domains 1
chr3_-_197024965 0.19 ENST00000392382.2
DLG1
discs, large homolog 1 (Drosophila)
chr2_+_220299547 0.19 ENST00000312358.7
SPEG
SPEG complex locus
chr9_-_130487143 0.19 ENST00000419060.1
PTRH1
peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae)
chr2_-_26467465 0.19 ENST00000457468.2
HADHA
hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
chr22_+_50354104 0.19 ENST00000360612.4
PIM3
pim-3 oncogene
chr11_+_67798363 0.18 ENST00000525628.1
NDUFS8
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr7_+_26591441 0.18 ENST00000420912.1
ENST00000457000.1
ENST00000430426.1
AC004947.2
AC004947.2
chr1_-_229569834 0.18 ENST00000366684.3
ENST00000366683.2
ACTA1
actin, alpha 1, skeletal muscle
chr22_-_36902522 0.18 ENST00000397223.4
FOXRED2
FAD-dependent oxidoreductase domain containing 2
chr17_-_49021974 0.17 ENST00000501718.2
RP11-700H6.1
RP11-700H6.1
chr8_+_22429205 0.17 ENST00000520207.1
SORBS3
sorbin and SH3 domain containing 3
chr1_+_36690011 0.16 ENST00000354618.5
ENST00000469141.2
ENST00000478853.1
THRAP3
thyroid hormone receptor associated protein 3
chr12_+_51818749 0.16 ENST00000514353.3
SLC4A8
solute carrier family 4, sodium bicarbonate cotransporter, member 8
chr17_-_10276319 0.16 ENST00000252172.4
ENST00000418404.3
MYH13
myosin, heavy chain 13, skeletal muscle
chr9_-_96215822 0.16 ENST00000375412.5
FAM120AOS
family with sequence similarity 120A opposite strand
chr8_-_145018905 0.16 ENST00000398774.2
PLEC
plectin
chr17_-_1553346 0.16 ENST00000301336.6
RILP
Rab interacting lysosomal protein
chr4_+_41614720 0.15 ENST00000509277.1
LIMCH1
LIM and calponin homology domains 1
chr16_-_70729496 0.15 ENST00000567648.1
VAC14
Vac14 homolog (S. cerevisiae)
chr11_+_76571911 0.15 ENST00000534206.1
ENST00000532485.1
ENST00000526597.1
ENST00000533873.1
ENST00000538157.1
ACER3
alkaline ceramidase 3
chr7_+_73245193 0.15 ENST00000340958.2
CLDN4
claudin 4
chr12_-_120554622 0.15 ENST00000229340.5
RAB35
RAB35, member RAS oncogene family
chr17_+_45973516 0.14 ENST00000376741.4
SP2
Sp2 transcription factor
chr1_-_157108130 0.14 ENST00000368192.4
ETV3
ets variant 3
chr22_-_30960876 0.14 ENST00000401975.1
ENST00000428682.1
ENST00000423299.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chr2_-_220110111 0.14 ENST00000428427.1
ENST00000356283.3
ENST00000432839.1
ENST00000424620.1
GLB1L
galactosidase, beta 1-like
chr12_+_51818555 0.14 ENST00000453097.2
SLC4A8
solute carrier family 4, sodium bicarbonate cotransporter, member 8
chr17_+_36858694 0.14 ENST00000563897.1
CTB-58E17.1
CTB-58E17.1
chr3_-_167452262 0.14 ENST00000487947.2
PDCD10
programmed cell death 10
chr2_-_207024134 0.14 ENST00000457011.1
ENST00000440274.1
ENST00000432169.1
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr4_+_48343339 0.14 ENST00000264313.6
SLAIN2
SLAIN motif family, member 2
chr1_-_27816641 0.14 ENST00000430629.2
WASF2
WAS protein family, member 2
chr11_-_64511789 0.13 ENST00000419843.1
ENST00000394430.1
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr22_+_20104947 0.13 ENST00000402752.1
RANBP1
RAN binding protein 1
chr12_+_51818586 0.13 ENST00000394856.1
SLC4A8
solute carrier family 4, sodium bicarbonate cotransporter, member 8
chr19_-_55874611 0.13 ENST00000424985.3
FAM71E2
family with sequence similarity 71, member E2
chr19_+_4153598 0.13 ENST00000078445.2
ENST00000252587.3
ENST00000595923.1
ENST00000602257.1
ENST00000602147.1
CREB3L3
cAMP responsive element binding protein 3-like 3
chr22_-_37880543 0.13 ENST00000442496.1
MFNG
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr16_-_85833109 0.13 ENST00000253457.3
EMC8
ER membrane protein complex subunit 8
chr6_-_31628512 0.13 ENST00000375911.1
C6orf47
chromosome 6 open reading frame 47
chr2_-_207023918 0.13 ENST00000455934.2
ENST00000449699.1
ENST00000454195.1
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr15_-_41408409 0.12 ENST00000361937.3
INO80
INO80 complex subunit
chr3_-_113465065 0.12 ENST00000497255.1
ENST00000478020.1
ENST00000240922.3
ENST00000493900.1
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr20_+_57875658 0.12 ENST00000371025.3
EDN3
endothelin 3
chr2_-_25194476 0.12 ENST00000534855.1
DNAJC27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr1_+_201924619 0.12 ENST00000367287.4
TIMM17A
translocase of inner mitochondrial membrane 17 homolog A (yeast)
chr9_+_95997205 0.12 ENST00000411624.1
WNK2
WNK lysine deficient protein kinase 2
chr11_-_78052923 0.11 ENST00000340149.2
GAB2
GRB2-associated binding protein 2
chr9_-_34048873 0.11 ENST00000449054.1
ENST00000379239.4
ENST00000539807.1
ENST00000379238.1
ENST00000418786.2
ENST00000360802.1
ENST00000412543.1
UBAP2
ubiquitin associated protein 2
chr1_+_26348259 0.11 ENST00000374280.3
EXTL1
exostosin-like glycosyltransferase 1
chr15_-_41120896 0.11 ENST00000299174.5
ENST00000427255.2
PPP1R14D
protein phosphatase 1, regulatory (inhibitor) subunit 14D
chr8_+_134203303 0.11 ENST00000519433.1
ENST00000517423.1
ENST00000377863.2
ENST00000220856.6
WISP1
WNT1 inducible signaling pathway protein 1
chr16_-_66952742 0.11 ENST00000565235.2
ENST00000568632.1
ENST00000565796.1
CDH16
cadherin 16, KSP-cadherin
chr8_+_145582633 0.11 ENST00000540505.1
SLC52A2
solute carrier family 52 (riboflavin transporter), member 2
chr10_+_11207438 0.10 ENST00000609692.1
ENST00000354897.3
CELF2
CUGBP, Elav-like family member 2
chr4_+_41614909 0.10 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1
LIM and calponin homology domains 1
chr6_-_87804815 0.10 ENST00000369582.2
CGA
glycoprotein hormones, alpha polypeptide
chr16_-_745946 0.10 ENST00000562563.1
FBXL16
F-box and leucine-rich repeat protein 16
chr17_+_79679299 0.10 ENST00000331531.5
SLC25A10
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr12_-_56753858 0.10 ENST00000314128.4
ENST00000557235.1
ENST00000418572.2
STAT2
signal transducer and activator of transcription 2, 113kDa
chr4_-_65275162 0.10 ENST00000381210.3
ENST00000507440.1
TECRL
trans-2,3-enoyl-CoA reductase-like
chr3_-_151034734 0.10 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr5_-_137878887 0.10 ENST00000507939.1
ENST00000572514.1
ENST00000499810.2
ENST00000360541.5
ETF1
eukaryotic translation termination factor 1
chr17_+_79679369 0.10 ENST00000350690.5
SLC25A10
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr12_+_93963590 0.10 ENST00000340600.2
SOCS2
suppressor of cytokine signaling 2
chr8_-_70745575 0.10 ENST00000524945.1
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr14_+_42076765 0.09 ENST00000298119.4
LRFN5
leucine rich repeat and fibronectin type III domain containing 5
chr22_+_18121562 0.09 ENST00000355028.3
BCL2L13
BCL2-like 13 (apoptosis facilitator)
chr16_-_58328923 0.09 ENST00000567164.1
ENST00000219301.4
ENST00000569727.1
PRSS54
protease, serine, 54
chr19_+_49547099 0.09 ENST00000301408.6
CGB5
chorionic gonadotropin, beta polypeptide 5
chr11_+_67798114 0.09 ENST00000453471.2
ENST00000528492.1
ENST00000526339.1
ENST00000525419.1
NDUFS8
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr19_-_8008533 0.09 ENST00000597926.1
TIMM44
translocase of inner mitochondrial membrane 44 homolog (yeast)
chr4_+_24797085 0.09 ENST00000382120.3
SOD3
superoxide dismutase 3, extracellular
chr15_+_78441663 0.09 ENST00000299518.2
ENST00000558554.1
ENST00000557826.1
ENST00000561279.1
ENST00000559186.1
ENST00000560770.1
ENST00000559881.1
ENST00000559205.1
ENST00000441490.2
IDH3A
isocitrate dehydrogenase 3 (NAD+) alpha
chr17_+_79670386 0.09 ENST00000333676.3
ENST00000571730.1
ENST00000541223.1
MRPL12
SLC25A10
SLC25A10
mitochondrial ribosomal protein L12
Mitochondrial dicarboxylate carrier; Uncharacterized protein; cDNA FLJ60124, highly similar to Mitochondrial dicarboxylate carrier
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr17_-_2614927 0.09 ENST00000435359.1
CLUH
clustered mitochondria (cluA/CLU1) homolog
chr2_+_210288760 0.08 ENST00000199940.6
MAP2
microtubule-associated protein 2
chr16_+_3704822 0.08 ENST00000414110.2
DNASE1
deoxyribonuclease I
chr11_+_12766583 0.08 ENST00000361985.2
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr7_+_129007964 0.08 ENST00000460109.1
ENST00000474594.1
ENST00000446212.1
AHCYL2
adenosylhomocysteinase-like 2
chr11_-_64013663 0.08 ENST00000392210.2
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr19_-_10446449 0.08 ENST00000592439.1
ICAM3
intercellular adhesion molecule 3
chrX_-_150067272 0.07 ENST00000355149.3
ENST00000437787.2
CD99L2
CD99 molecule-like 2
chr10_-_101841588 0.07 ENST00000370418.3
CPN1
carboxypeptidase N, polypeptide 1
chr22_-_27620603 0.07 ENST00000418271.1
ENST00000444114.1
RP5-1172A22.1
RP5-1172A22.1
chr1_+_45140360 0.07 ENST00000418644.1
ENST00000458657.2
ENST00000441519.1
ENST00000535358.1
ENST00000445071.1
C1orf228
chromosome 1 open reading frame 228
chr16_-_58328870 0.07 ENST00000543437.1
PRSS54
protease, serine, 54
chr17_-_56358287 0.07 ENST00000225275.3
ENST00000340482.3
MPO
myeloperoxidase
chr6_-_76072719 0.07 ENST00000370020.1
FILIP1
filamin A interacting protein 1
chr10_-_51623203 0.07 ENST00000444743.1
ENST00000374065.3
ENST00000374064.3
ENST00000260867.4
TIMM23
translocase of inner mitochondrial membrane 23 homolog (yeast)
chr16_+_30937213 0.07 ENST00000427128.1
FBXL19
F-box and leucine-rich repeat protein 19
chr14_+_21498360 0.07 ENST00000321760.6
ENST00000460647.2
ENST00000530140.2
ENST00000472458.1
TPPP2
tubulin polymerization-promoting protein family member 2
chr9_+_113431059 0.07 ENST00000416899.2
MUSK
muscle, skeletal, receptor tyrosine kinase
chr11_-_64014379 0.06 ENST00000309318.3
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr3_+_138340067 0.06 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chr22_-_30783075 0.06 ENST00000215798.6
RNF215
ring finger protein 215
chr5_+_149569520 0.06 ENST00000230671.2
ENST00000524041.1
SLC6A7
solute carrier family 6 (neurotransmitter transporter), member 7
chrX_-_150067173 0.06 ENST00000370377.3
ENST00000320893.6
CD99L2
CD99 molecule-like 2
chr4_-_151936865 0.06 ENST00000535741.1
LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chr12_-_108955070 0.06 ENST00000228284.3
ENST00000546611.1
SART3
squamous cell carcinoma antigen recognized by T cells 3
chr3_+_128968437 0.06 ENST00000314797.6
COPG1
coatomer protein complex, subunit gamma 1
chr2_-_26467557 0.06 ENST00000380649.3
HADHA
hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
chr20_+_47538357 0.05 ENST00000371917.4
ARFGEF2
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr20_+_57875457 0.05 ENST00000337938.2
ENST00000311585.7
ENST00000371028.2
EDN3
endothelin 3
chr15_+_43985725 0.05 ENST00000413453.2
CKMT1A
creatine kinase, mitochondrial 1A
chr4_-_122872909 0.05 ENST00000379645.3
TRPC3
transient receptor potential cation channel, subfamily C, member 3
chr16_-_28937027 0.05 ENST00000358201.4
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chr16_+_30675654 0.05 ENST00000287468.5
ENST00000395073.2
FBRS
fibrosin
chr9_-_115983641 0.05 ENST00000238256.3
FKBP15
FK506 binding protein 15, 133kDa
chr12_-_63544718 0.05 ENST00000299178.2
AVPR1A
arginine vasopressin receptor 1A
chr1_-_154164534 0.05 ENST00000271850.7
ENST00000368530.2
TPM3
tropomyosin 3
chr9_+_113431029 0.05 ENST00000189978.5
ENST00000374448.4
ENST00000374440.3
MUSK
muscle, skeletal, receptor tyrosine kinase
chrY_-_15591485 0.05 ENST00000382896.4
ENST00000537580.1
ENST00000540140.1
ENST00000545955.1
ENST00000538878.1
UTY
ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
chr1_-_20987889 0.05 ENST00000415136.2
DDOST
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
chr7_-_81399438 0.05 ENST00000222390.5
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr11_-_790060 0.05 ENST00000330106.4
CEND1
cell cycle exit and neuronal differentiation 1
chr2_-_121223697 0.05 ENST00000593290.1
FLJ14816
long intergenic non-protein coding RNA 1101
chr3_+_138340049 0.05 ENST00000464668.1
FAIM
Fas apoptotic inhibitory molecule
chr14_+_22320634 0.05 ENST00000390435.1
TRAV8-3
T cell receptor alpha variable 8-3
chr12_-_22487618 0.05 ENST00000404299.3
ENST00000396037.4
ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr19_+_8509842 0.04 ENST00000325495.4
ENST00000600092.1
ENST00000594907.1
ENST00000596984.1
ENST00000601645.1
HNRNPM
heterogeneous nuclear ribonucleoprotein M
chr3_+_9745510 0.04 ENST00000383831.3
CPNE9
copine family member IX

Network of associatons between targets according to the STRING database.

First level regulatory network of NR4A2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.5 1.5 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.3 1.0 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.3 1.0 GO:1900075 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
0.3 1.8 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.3 0.9 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.3 0.9 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.2 1.1 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.2 0.5 GO:0007518 myoblast fate determination(GO:0007518)
0.1 0.6 GO:0044861 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281) positive regulation of potassium ion import(GO:1903288)
0.1 0.2 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 0.3 GO:1902356 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.1 0.3 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.1 0.6 GO:0006642 triglyceride mobilization(GO:0006642)
0.1 0.2 GO:1903028 positive regulation of opsonization(GO:1903028)
0.1 0.4 GO:0070560 protein secretion by platelet(GO:0070560)
0.1 0.8 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.1 0.2 GO:0070676 regulation of multivesicular body size(GO:0010796) intralumenal vesicle formation(GO:0070676)
0.1 0.2 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.0 0.1 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.0 GO:0021699 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.0 0.2 GO:2000211 negative regulation of cellular amino acid metabolic process(GO:0045763) regulation of glutamate metabolic process(GO:2000211)
0.0 0.6 GO:0044351 macropinocytosis(GO:0044351)
0.0 0.3 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.0 0.5 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.4 GO:0015705 iodide transport(GO:0015705)
0.0 0.3 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.2 GO:1903286 regulation of potassium ion import(GO:1903286)
0.0 0.5 GO:0097012 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.7 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.0 0.4 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.2 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.7 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.2 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.4 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.2 GO:0019236 response to pheromone(GO:0019236)
0.0 0.8 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.7 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.1 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.5 GO:0035855 positive regulation of lamellipodium assembly(GO:0010592) megakaryocyte development(GO:0035855)
0.0 0.1 GO:0002125 maternal aggressive behavior(GO:0002125)
0.0 0.4 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.3 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 0.1 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.3 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 0.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.5 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.0 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.1 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.1 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.7 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.0 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.1 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.1 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.2 0.9 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 0.5 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 1.1 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.3 GO:0071001 U4/U6 snRNP(GO:0071001)
0.1 1.0 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.1 0.5 GO:0031415 NatA complex(GO:0031415)
0.1 0.3 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.5 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 1.3 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0 0.4 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.4 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 0.4 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.4 GO:0031095 spectrin-associated cytoskeleton(GO:0014731) platelet dense tubular network membrane(GO:0031095)
0.0 0.2 GO:0043219 lateral loop(GO:0043219)
0.0 0.1 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.8 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.4 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.2 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.1 GO:0032279 axonemal microtubule(GO:0005879) asymmetric synapse(GO:0032279)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.3 1.8 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.4 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.1 0.6 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.7 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.1 1.0 GO:0019238 cyclohydrolase activity(GO:0019238)
0.1 1.5 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.3 GO:0015131 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.1 0.4 GO:0008431 vitamin E binding(GO:0008431)
0.1 0.2 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.1 0.5 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 1.2 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.1 0.2 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.1 0.6 GO:0015266 protein channel activity(GO:0015266)
0.0 0.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 1.0 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 1.1 GO:0031489 myosin V binding(GO:0031489)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.7 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.3 GO:0005497 androgen binding(GO:0005497)
0.0 0.3 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.5 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.6 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.6 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.2 GO:0035473 lipase binding(GO:0035473)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.5 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.1 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.0 0.1 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.1 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.0 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.1 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.3 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.4 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.1 GO:0031893 vasopressin receptor binding(GO:0031893)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.9 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.7 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.0 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 1.8 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.9 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.8 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.1 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.6 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.7 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.9 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling