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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for NR4A3

Z-value: 0.81

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Transcription factors associated with NR4A3

Gene Symbol Gene ID Gene Info
NR4A3
ENSG00000119508.13 nuclear receptor subfamily 4 group A member 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR4A3hg19_v2_chr9_+_102584128_1025841440.096.8e-01Click!

Activity profile of NR4A3 motif

Sorted Z-values of NR4A3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_228678550 2.96 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr12_+_32655110 1.61 ENST00000546442.1
ENST00000583694.1
FGD4
FYVE, RhoGEF and PH domain containing 4
chr6_-_11807277 1.34 ENST00000379415.2
ADTRP
androgen-dependent TFPI-regulating protein
chr22_+_21128167 1.33 ENST00000215727.5
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr12_+_113376157 1.23 ENST00000228928.7
OAS3
2'-5'-oligoadenylate synthetase 3, 100kDa
chr11_+_35198243 1.18 ENST00000528455.1
CD44
CD44 molecule (Indian blood group)
chr11_+_35198118 1.18 ENST00000525211.1
ENST00000526000.1
ENST00000279452.6
ENST00000527889.1
CD44
CD44 molecule (Indian blood group)
chr11_+_71710648 1.12 ENST00000260049.5
IL18BP
interleukin 18 binding protein
chr3_+_101546827 1.11 ENST00000461724.1
ENST00000483180.1
ENST00000394054.2
NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr14_+_24630465 1.07 ENST00000557894.1
ENST00000559284.1
ENST00000560275.1
IRF9
interferon regulatory factor 9
chr14_-_107283278 0.94 ENST00000390639.2
IGHV7-81
immunoglobulin heavy variable 7-81 (non-functional)
chr9_+_124103625 0.91 ENST00000594963.1
AL161784.1
Uncharacterized protein
chr12_-_31158902 0.85 ENST00000544329.1
ENST00000418254.2
ENST00000222396.5
RP11-551L14.4
RP11-551L14.4
chr1_-_38218577 0.73 ENST00000540011.1
EPHA10
EPH receptor A10
chr16_+_88872176 0.71 ENST00000569140.1
CDT1
chromatin licensing and DNA replication factor 1
chr16_+_691792 0.69 ENST00000307650.4
FAM195A
family with sequence similarity 195, member A
chr7_+_100547156 0.67 ENST00000379458.4
MUC3A
Protein LOC100131514
chr19_+_10197463 0.63 ENST00000590378.1
ENST00000397881.3
C19orf66
chromosome 19 open reading frame 66
chr16_+_57653989 0.63 ENST00000567835.1
ENST00000569372.1
ENST00000563548.1
ENST00000562003.1
GPR56
G protein-coupled receptor 56
chr19_-_633576 0.62 ENST00000588649.2
POLRMT
polymerase (RNA) mitochondrial (DNA directed)
chr20_+_58179582 0.60 ENST00000371015.1
ENST00000395639.4
PHACTR3
phosphatase and actin regulator 3
chr3_+_29323043 0.57 ENST00000452462.1
ENST00000456853.1
RBMS3
RNA binding motif, single stranded interacting protein 3
chr18_+_21719018 0.56 ENST00000585037.1
ENST00000415309.2
ENST00000399481.2
ENST00000577705.1
ENST00000327201.6
CABYR
calcium binding tyrosine-(Y)-phosphorylation regulated
chr22_+_31518938 0.56 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
INPP5J
inositol polyphosphate-5-phosphatase J
chr1_-_36916066 0.56 ENST00000315643.9
OSCP1
organic solute carrier partner 1
chr16_+_11038403 0.54 ENST00000409552.3
CLEC16A
C-type lectin domain family 16, member A
chr15_-_91475706 0.53 ENST00000561036.1
HDDC3
HD domain containing 3
chr20_+_61287711 0.53 ENST00000370507.1
SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr19_-_49552363 0.52 ENST00000448456.3
ENST00000355414.2
CGB8
chorionic gonadotropin, beta polypeptide 8
chr22_+_31488433 0.52 ENST00000455608.1
SMTN
smoothelin
chr11_-_73720276 0.51 ENST00000348534.4
UCP3
uncoupling protein 3 (mitochondrial, proton carrier)
chr16_+_57653854 0.49 ENST00000568908.1
ENST00000568909.1
ENST00000566778.1
ENST00000561988.1
GPR56
G protein-coupled receptor 56
chr20_-_62130474 0.49 ENST00000217182.3
EEF1A2
eukaryotic translation elongation factor 1 alpha 2
chr1_-_36906474 0.49 ENST00000433045.2
OSCP1
organic solute carrier partner 1
chr7_-_139763521 0.48 ENST00000263549.3
PARP12
poly (ADP-ribose) polymerase family, member 12
chr9_-_117568365 0.48 ENST00000374045.4
TNFSF15
tumor necrosis factor (ligand) superfamily, member 15
chr17_-_40264692 0.48 ENST00000591220.1
ENST00000251642.3
DHX58
DEXH (Asp-Glu-X-His) box polypeptide 58
chr12_+_49717081 0.46 ENST00000547807.1
ENST00000551567.1
TROAP
trophinin associated protein
chr16_-_67969888 0.46 ENST00000574576.2
PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
chr19_-_49552006 0.46 ENST00000391869.3
CGB1
chorionic gonadotropin, beta polypeptide 1
chr12_-_6451186 0.46 ENST00000540022.1
ENST00000536194.1
TNFRSF1A
tumor necrosis factor receptor superfamily, member 1A
chr17_+_32646055 0.46 ENST00000394620.1
CCL8
chemokine (C-C motif) ligand 8
chr8_-_145018905 0.45 ENST00000398774.2
PLEC
plectin
chr8_+_145149930 0.45 ENST00000318911.4
CYC1
cytochrome c-1
chr7_+_75027418 0.45 ENST00000447409.2
TRIM73
tripartite motif containing 73
chr7_-_102715172 0.45 ENST00000456695.1
ENST00000455112.2
ENST00000440067.1
FBXL13
F-box and leucine-rich repeat protein 13
chr3_-_58613323 0.45 ENST00000474531.1
ENST00000465970.1
FAM107A
family with sequence similarity 107, member A
chr12_-_8088871 0.44 ENST00000075120.7
SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chrX_-_108868390 0.44 ENST00000372101.2
KCNE1L
KCNE1-like
chr5_-_150466692 0.44 ENST00000315050.7
ENST00000523338.1
ENST00000522100.1
TNIP1
TNFAIP3 interacting protein 1
chr22_+_24891210 0.44 ENST00000382760.2
UPB1
ureidopropionase, beta
chr8_-_144897138 0.43 ENST00000377533.3
SCRIB
scribbled planar cell polarity protein
chr9_-_95896550 0.43 ENST00000375446.4
NINJ1
ninjurin 1
chr4_+_154622652 0.43 ENST00000260010.6
TLR2
toll-like receptor 2
chr3_-_9994021 0.43 ENST00000411976.2
ENST00000412055.1
PRRT3
proline-rich transmembrane protein 3
chr15_+_72947079 0.42 ENST00000421285.3
GOLGA6B
golgin A6 family, member B
chr1_-_36916011 0.42 ENST00000356637.5
ENST00000354267.3
ENST00000235532.5
OSCP1
organic solute carrier partner 1
chr16_-_87970122 0.42 ENST00000309893.2
CA5A
carbonic anhydrase VA, mitochondrial
chr16_+_56598961 0.42 ENST00000219162.3
MT4
metallothionein 4
chr10_+_104005272 0.41 ENST00000369983.3
GBF1
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr1_-_40042416 0.41 ENST00000372857.3
ENST00000372856.3
ENST00000531243.2
ENST00000451091.2
PABPC4
poly(A) binding protein, cytoplasmic 4 (inducible form)
chr6_+_18155632 0.41 ENST00000297792.5
KDM1B
lysine (K)-specific demethylase 1B
chr1_+_212738676 0.40 ENST00000366981.4
ENST00000366987.2
ATF3
activating transcription factor 3
chr10_+_81107271 0.40 ENST00000448165.1
PPIF
peptidylprolyl isomerase F
chr7_-_27169801 0.39 ENST00000511914.1
HOXA4
homeobox A4
chr7_+_13141097 0.39 ENST00000411542.1
AC011288.2
AC011288.2
chrX_-_39923656 0.39 ENST00000413905.1
BCOR
BCL6 corepressor
chr1_+_113217345 0.39 ENST00000357443.2
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr1_+_113217309 0.38 ENST00000544796.1
ENST00000369644.1
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr1_+_113217043 0.38 ENST00000413052.2
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr4_-_76928641 0.38 ENST00000264888.5
CXCL9
chemokine (C-X-C motif) ligand 9
chr5_-_59481406 0.37 ENST00000546160.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr15_-_78423567 0.37 ENST00000561190.1
ENST00000559645.1
ENST00000560618.1
ENST00000559054.1
CIB2
calcium and integrin binding family member 2
chr12_+_49717019 0.37 ENST00000549275.1
ENST00000551245.1
ENST00000380327.5
ENST00000548311.1
ENST00000550346.1
ENST00000550709.1
ENST00000549534.1
ENST00000257909.3
TROAP
trophinin associated protein
chr15_-_91475747 0.37 ENST00000330334.3
ENST00000559898.1
ENST00000394272.3
HDDC3
HD domain containing 3
chr22_+_38609538 0.37 ENST00000407965.1
MAFF
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
chr4_-_120548779 0.37 ENST00000264805.5
PDE5A
phosphodiesterase 5A, cGMP-specific
chr1_+_113217073 0.36 ENST00000369645.1
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr2_+_113763031 0.36 ENST00000259211.6
IL36A
interleukin 36, alpha
chr19_+_10196981 0.36 ENST00000591813.1
C19orf66
chromosome 19 open reading frame 66
chr7_-_151433342 0.36 ENST00000433631.2
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr1_-_229569834 0.35 ENST00000366684.3
ENST00000366683.2
ACTA1
actin, alpha 1, skeletal muscle
chr17_-_2996290 0.35 ENST00000331459.1
OR1D2
olfactory receptor, family 1, subfamily D, member 2
chr11_+_64073699 0.35 ENST00000405666.1
ENST00000468670.1
ESRRA
estrogen-related receptor alpha
chr14_+_22984601 0.35 ENST00000390509.1
TRAJ28
T cell receptor alpha joining 28
chr1_-_200992827 0.35 ENST00000332129.2
ENST00000422435.2
KIF21B
kinesin family member 21B
chr1_+_203097407 0.34 ENST00000367235.1
ADORA1
adenosine A1 receptor
chr1_-_11107280 0.34 ENST00000400897.3
ENST00000400898.3
MASP2
mannan-binding lectin serine peptidase 2
chr14_+_74035763 0.34 ENST00000238651.5
ACOT2
acyl-CoA thioesterase 2
chr8_+_145202939 0.34 ENST00000423230.2
ENST00000398656.4
MROH1
maestro heat-like repeat family member 1
chr13_-_46679144 0.34 ENST00000181383.4
CPB2
carboxypeptidase B2 (plasma)
chr3_-_190167571 0.33 ENST00000354905.2
TMEM207
transmembrane protein 207
chr13_-_46679185 0.33 ENST00000439329.3
CPB2
carboxypeptidase B2 (plasma)
chr1_+_64059332 0.33 ENST00000540265.1
PGM1
phosphoglucomutase 1
chr21_-_36421626 0.33 ENST00000300305.3
RUNX1
runt-related transcription factor 1
chr6_-_43027105 0.32 ENST00000230413.5
ENST00000487429.1
ENST00000489623.1
ENST00000468957.1
MRPL2
mitochondrial ribosomal protein L2
chr1_+_64239657 0.32 ENST00000371080.1
ENST00000371079.1
ROR1
receptor tyrosine kinase-like orphan receptor 1
chr7_+_45613958 0.32 ENST00000297323.7
ADCY1
adenylate cyclase 1 (brain)
chr19_-_10679644 0.32 ENST00000393599.2
CDKN2D
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr13_+_113760098 0.32 ENST00000346342.3
ENST00000541084.1
ENST00000375581.3
F7
coagulation factor VII (serum prothrombin conversion accelerator)
chr9_+_103189660 0.32 ENST00000374886.3
MSANTD3
Myb/SANT-like DNA-binding domain containing 3
chr16_+_56995854 0.31 ENST00000566128.1
CETP
cholesteryl ester transfer protein, plasma
chr17_+_71161140 0.31 ENST00000357585.2
SSTR2
somatostatin receptor 2
chr15_-_42783303 0.31 ENST00000565380.1
ENST00000564754.1
ZNF106
zinc finger protein 106
chr5_+_133984462 0.31 ENST00000398844.2
ENST00000322887.4
SEC24A
SEC24 family member A
chr20_-_60982330 0.31 ENST00000279101.5
CABLES2
Cdk5 and Abl enzyme substrate 2
chr19_+_39616410 0.31 ENST00000602004.1
ENST00000599470.1
ENST00000321944.4
ENST00000593480.1
ENST00000358301.3
ENST00000593690.1
ENST00000599386.1
PAK4
p21 protein (Cdc42/Rac)-activated kinase 4
chr14_+_21498666 0.31 ENST00000481535.1
TPPP2
tubulin polymerization-promoting protein family member 2
chr4_-_111563076 0.31 ENST00000354925.2
ENST00000511990.1
PITX2
paired-like homeodomain 2
chr11_-_117698765 0.31 ENST00000532119.1
FXYD2
FXYD domain containing ion transport regulator 2
chr7_-_151433393 0.30 ENST00000492843.1
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr2_-_231989808 0.30 ENST00000258400.3
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chrX_-_40036520 0.30 ENST00000406200.2
ENST00000378455.4
ENST00000342274.4
BCOR
BCL6 corepressor
chr11_-_110583912 0.30 ENST00000533353.1
ENST00000527598.1
ARHGAP20
Rho GTPase activating protein 20
chr14_-_24658053 0.30 ENST00000354464.6
IPO4
importin 4
chr19_+_35630628 0.30 ENST00000588715.1
ENST00000588607.1
FXYD1
FXYD domain containing ion transport regulator 1
chr4_-_681114 0.30 ENST00000503156.1
MFSD7
major facilitator superfamily domain containing 7
chr3_+_133292851 0.30 ENST00000503932.1
CDV3
CDV3 homolog (mouse)
chr9_-_130517522 0.29 ENST00000373274.3
ENST00000420366.1
SH2D3C
SH2 domain containing 3C
chr20_-_23860373 0.29 ENST00000304710.4
CST5
cystatin D
chr7_+_142498725 0.29 ENST00000466254.1
TRBC2
T cell receptor beta constant 2
chr5_-_150473127 0.29 ENST00000521001.1
TNIP1
TNFAIP3 interacting protein 1
chr7_+_22766766 0.29 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
IL6
interleukin 6 (interferon, beta 2)
chr1_-_155232047 0.28 ENST00000302631.3
SCAMP3
secretory carrier membrane protein 3
chr22_+_20104947 0.28 ENST00000402752.1
RANBP1
RAN binding protein 1
chrX_-_77225135 0.28 ENST00000458128.1
PGAM4
phosphoglycerate mutase family member 4
chr5_+_52285144 0.28 ENST00000296585.5
ITGA2
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
chr22_+_30821732 0.28 ENST00000355143.4
MTFP1
mitochondrial fission process 1
chr11_-_117699413 0.28 ENST00000528014.1
FXYD2
FXYD domain containing ion transport regulator 2
chr14_-_101295407 0.27 ENST00000596284.1
AL117190.2
AL117190.2
chr13_+_28194873 0.27 ENST00000302979.3
POLR1D
polymerase (RNA) I polypeptide D, 16kDa
chr9_-_130487143 0.27 ENST00000419060.1
PTRH1
peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae)
chr15_+_75575176 0.27 ENST00000434739.3
GOLGA6D
golgin A6 family, member D
chr17_-_4852332 0.27 ENST00000572383.1
PFN1
profilin 1
chr8_+_124084899 0.27 ENST00000287380.1
ENST00000309336.3
ENST00000519418.1
ENST00000327098.5
ENST00000522420.1
ENST00000521676.1
ENST00000378080.2
TBC1D31
TBC1 domain family, member 31
chr17_+_79679369 0.27 ENST00000350690.5
SLC25A10
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr22_-_24384260 0.27 ENST00000248935.5
GSTT1
glutathione S-transferase theta 1
chr1_-_155232221 0.27 ENST00000355379.3
SCAMP3
secretory carrier membrane protein 3
chr19_-_35166604 0.27 ENST00000601241.1
SCGB2B2
secretoglobin, family 2B, member 2
chr22_-_24384240 0.27 ENST00000439996.2
ENST00000417870.1
GSTT1
glutathione S-transferase theta 1
chr1_+_25071848 0.26 ENST00000374379.4
CLIC4
chloride intracellular channel 4
chr4_-_48014931 0.26 ENST00000420489.2
ENST00000504722.1
CNGA1
cyclic nucleotide gated channel alpha 1
chr1_-_2461684 0.26 ENST00000378453.3
HES5
hes family bHLH transcription factor 5
chr12_-_6451235 0.26 ENST00000440083.2
ENST00000162749.2
TNFRSF1A
tumor necrosis factor receptor superfamily, member 1A
chr1_-_20306909 0.26 ENST00000375111.3
ENST00000400520.3
PLA2G2A
phospholipase A2, group IIA (platelets, synovial fluid)
chr8_-_70745575 0.26 ENST00000524945.1
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr16_-_73082274 0.25 ENST00000268489.5
ZFHX3
zinc finger homeobox 3
chr19_-_48867171 0.25 ENST00000377431.2
ENST00000436660.2
ENST00000541566.1
TMEM143
transmembrane protein 143
chr17_-_39254391 0.25 ENST00000333822.4
KRTAP4-8
keratin associated protein 4-8
chr15_+_45422178 0.25 ENST00000389037.3
ENST00000558322.1
DUOX1
dual oxidase 1
chr2_-_179567206 0.25 ENST00000414766.1
TTN
titin
chr11_+_17741111 0.25 ENST00000250003.3
MYOD1
myogenic differentiation 1
chr17_-_2169425 0.24 ENST00000570606.1
ENST00000354901.4
SMG6
SMG6 nonsense mediated mRNA decay factor
chr4_-_40632605 0.24 ENST00000514014.1
RBM47
RNA binding motif protein 47
chr3_-_49314640 0.24 ENST00000436325.1
C3orf62
chromosome 3 open reading frame 62
chr15_+_45422131 0.24 ENST00000321429.4
DUOX1
dual oxidase 1
chr9_-_140095186 0.24 ENST00000409012.4
TPRN
taperin
chr19_+_926000 0.24 ENST00000263620.3
ARID3A
AT rich interactive domain 3A (BRIGHT-like)
chr3_+_46449049 0.24 ENST00000357392.4
ENST00000400880.3
ENST00000433848.1
CCRL2
chemokine (C-C motif) receptor-like 2
chr16_+_4674787 0.24 ENST00000262370.7
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr10_-_50970322 0.23 ENST00000374103.4
OGDHL
oxoglutarate dehydrogenase-like
chr1_+_150480576 0.23 ENST00000346569.6
ECM1
extracellular matrix protein 1
chr2_+_234686976 0.23 ENST00000389758.3
MROH2A
maestro heat-like repeat family member 2A
chr7_+_16566449 0.23 ENST00000401542.2
LRRC72
leucine rich repeat containing 72
chr5_+_34656569 0.23 ENST00000428746.2
RAI14
retinoic acid induced 14
chr19_+_45394477 0.23 ENST00000252487.5
ENST00000405636.2
ENST00000592434.1
ENST00000426677.2
ENST00000589649.1
TOMM40
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr12_+_45686457 0.23 ENST00000441606.2
ANO6
anoctamin 6
chr17_+_41132564 0.23 ENST00000361677.1
ENST00000589705.1
RUNDC1
RUN domain containing 1
chr1_-_36915880 0.23 ENST00000445843.3
OSCP1
organic solute carrier partner 1
chrX_-_47489244 0.23 ENST00000469388.1
ENST00000396992.3
ENST00000377005.2
CFP
complement factor properdin
chr9_-_72435576 0.23 ENST00000453410.1
ENST00000526458.1
ENST00000439418.1
C9orf135-AS1
C9orf135 antisense RNA 1 (head to head)
chr4_-_40859132 0.23 ENST00000543538.1
ENST00000502841.1
ENST00000504305.1
ENST00000513516.1
ENST00000510670.1
APBB2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr10_-_50970382 0.23 ENST00000419399.1
ENST00000432695.1
OGDHL
oxoglutarate dehydrogenase-like
chr16_+_27413483 0.23 ENST00000337929.3
ENST00000564089.1
IL21R
interleukin 21 receptor
chr11_-_117698787 0.22 ENST00000260287.2
FXYD2
FXYD domain containing ion transport regulator 2
chr10_-_105845674 0.22 ENST00000353479.5
ENST00000369733.3
COL17A1
collagen, type XVII, alpha 1
chr1_-_161102367 0.22 ENST00000464113.1
DEDD
death effector domain containing
chr12_+_119616447 0.22 ENST00000281938.2
HSPB8
heat shock 22kDa protein 8
chr11_+_10472223 0.22 ENST00000396554.3
ENST00000524866.1
AMPD3
adenosine monophosphate deaminase 3
chr22_-_24110063 0.22 ENST00000520222.1
ENST00000401675.3
CHCHD10
coiled-coil-helix-coiled-coil-helix domain containing 10
chr1_+_45205498 0.22 ENST00000372218.4
KIF2C
kinesin family member 2C
chr12_-_52761262 0.22 ENST00000257901.3
KRT85
keratin 85
chr2_-_31030277 0.22 ENST00000534090.2
ENST00000295055.8
CAPN13
calpain 13
chr1_+_45205478 0.22 ENST00000452259.1
ENST00000372224.4
KIF2C
kinesin family member 2C
chr11_-_65430554 0.22 ENST00000308639.9
ENST00000406246.3
RELA
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr11_+_63137251 0.22 ENST00000310969.4
ENST00000279178.3
SLC22A9
solute carrier family 22 (organic anion transporter), member 9
chr11_-_64825993 0.22 ENST00000340252.4
ENST00000355721.3
ENST00000356632.3
ENST00000355369.2
ENST00000339885.2
ENST00000358658.3
NAALADL1
N-acetylated alpha-linked acidic dipeptidase-like 1
chr3_+_10290596 0.21 ENST00000448281.2
TATDN2
TatD DNase domain containing 2
chr19_+_589893 0.21 ENST00000251287.2
HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr4_-_25032501 0.21 ENST00000382114.4
LGI2
leucine-rich repeat LGI family, member 2
chr3_-_47934234 0.21 ENST00000420772.2
MAP4
microtubule-associated protein 4
chr5_-_64858944 0.21 ENST00000508421.1
ENST00000510693.1
ENST00000514814.1
ENST00000515497.1
ENST00000396679.1
CENPK
centromere protein K
chr1_-_116311402 0.21 ENST00000261448.5
CASQ2
calsequestrin 2 (cardiac muscle)
chr14_-_23398565 0.21 ENST00000397440.4
ENST00000538452.1
ENST00000421938.2
ENST00000554867.1
ENST00000556616.1
ENST00000216350.8
ENST00000553550.1
ENST00000397441.2
ENST00000553897.1
PRMT5
protein arginine methyltransferase 5
chrX_+_47078069 0.21 ENST00000357227.4
ENST00000519758.1
ENST00000520893.1
ENST00000517426.1
CDK16
cyclin-dependent kinase 16
chr12_-_16761007 0.20 ENST00000354662.1
ENST00000441439.2
LMO3
LIM domain only 3 (rhombotin-like 2)
chr2_+_220363579 0.20 ENST00000313597.5
ENST00000373917.3
ENST00000358215.3
ENST00000373908.1
ENST00000455657.1
ENST00000435316.1
ENST00000341142.3
GMPPA
GDP-mannose pyrophosphorylase A
chr1_+_206858328 0.20 ENST00000367103.3
MAPKAPK2
mitogen-activated protein kinase-activated protein kinase 2
chr7_+_93535817 0.20 ENST00000248572.5
GNGT1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr12_+_58013693 0.20 ENST00000320442.4
ENST00000379218.2
SLC26A10
solute carrier family 26, member 10

Network of associatons between targets according to the STRING database.

First level regulatory network of NR4A3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.3 2.4 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.2 0.7 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.2 0.7 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.2 1.3 GO:0008218 bioluminescence(GO:0008218)
0.2 0.7 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.2 0.6 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.4 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.1 0.4 GO:0042495 detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.1 1.4 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.1 0.4 GO:0015743 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.1 1.5 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.1 0.5 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.1 0.4 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.4 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.1 0.6 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 0.5 GO:1900245 negative regulation of MDA-5 signaling pathway(GO:0039534) positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1 0.3 GO:0032242 regulation of nucleoside transport(GO:0032242) negative regulation of neurotrophin production(GO:0032900)
0.1 0.8 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.1 0.4 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.1 0.4 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 0.3 GO:0060127 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.1 0.3 GO:0002384 hepatic immune response(GO:0002384)
0.1 0.3 GO:0033341 regulation of collagen binding(GO:0033341)
0.1 0.3 GO:2000974 auditory receptor cell fate determination(GO:0042668) negative regulation of pro-B cell differentiation(GO:2000974)
0.1 0.2 GO:0007518 myoblast fate determination(GO:0007518)
0.1 0.5 GO:0042335 cuticle development(GO:0042335)
0.1 0.4 GO:0032571 response to vitamin K(GO:0032571)
0.1 0.5 GO:0031999 negative regulation of fatty acid beta-oxidation(GO:0031999)
0.1 0.3 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 1.1 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 0.4 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1 0.3 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.3 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1 0.2 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.1 0.2 GO:0046680 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
0.1 0.3 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1 0.4 GO:0090131 mesenchyme migration(GO:0090131)
0.1 0.2 GO:0018874 benzoate metabolic process(GO:0018874)
0.1 0.2 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.1 0.3 GO:0006196 AMP catabolic process(GO:0006196)
0.1 0.2 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.1 0.2 GO:0097045 phosphatidylserine exposure on blood platelet(GO:0097045)
0.1 0.7 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.1 0.2 GO:0014040 positive regulation of Schwann cell differentiation(GO:0014040)
0.1 0.4 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 0.2 GO:0043449 dibenzo-p-dioxin metabolic process(GO:0018894) cellular alkene metabolic process(GO:0043449)
0.1 0.4 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 0.2 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.1 0.3 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.2 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.3 GO:0010734 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.0 0.1 GO:2001293 malonyl-CoA metabolic process(GO:2001293)
0.0 0.2 GO:0000255 allantoin metabolic process(GO:0000255)
0.0 0.6 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.2 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 0.2 GO:0036022 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.0 0.2 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.4 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.1 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 0.1 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.0 0.4 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.3 GO:0006311 meiotic gene conversion(GO:0006311)
0.0 1.2 GO:1900115 extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.2 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.4 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.2 GO:0043606 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.3 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.2 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
0.0 0.2 GO:0003164 His-Purkinje system development(GO:0003164)
0.0 0.1 GO:0090301 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.0 0.2 GO:0035709 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.0 0.1 GO:0015744 succinate transport(GO:0015744) tricarboxylic acid transmembrane transport(GO:0035674) succinate transmembrane transport(GO:0071422)
0.0 0.2 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.3 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.0 0.2 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.0 0.3 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.0 0.1 GO:1903660 T-helper 1 cell lineage commitment(GO:0002296) cellular response to mercury ion(GO:0071288) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.1 GO:0015670 carbon dioxide transport(GO:0015670) dipeptide transport(GO:0042938)
0.0 0.4 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.2 GO:0032264 IMP salvage(GO:0032264)
0.0 0.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.1 GO:0061055 myotome development(GO:0061055)
0.0 0.6 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.2 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.2 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.3 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.2 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.1 GO:2000969 rhythmic synaptic transmission(GO:0060024) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0 0.3 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.0 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.0 0.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0030047 actin modification(GO:0030047)
0.0 0.3 GO:0048102 autophagic cell death(GO:0048102)
0.0 0.2 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.2 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.2 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.1 GO:0034963 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.0 0.5 GO:1990845 adaptive thermogenesis(GO:1990845)
0.0 0.2 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.3 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.1 GO:0002554 serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554)
0.0 0.7 GO:0046320 regulation of fatty acid oxidation(GO:0046320)
0.0 0.5 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.7 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.2 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.3 GO:0071415 cellular response to purine-containing compound(GO:0071415)
0.0 0.3 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 1.1 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.3 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.1 GO:0035565 regulation of pronephros size(GO:0035565) renal glucose absorption(GO:0035623)
0.0 0.1 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.0 0.1 GO:2000861 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) positive regulation of estrogen secretion(GO:2000863) regulation of estradiol secretion(GO:2000864) positive regulation of estradiol secretion(GO:2000866)
0.0 0.1 GO:0002035 brain renin-angiotensin system(GO:0002035) angiotensin-mediated drinking behavior(GO:0003051)
0.0 0.3 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.4 GO:0060033 anatomical structure regression(GO:0060033)
0.0 0.1 GO:0002159 desmosome assembly(GO:0002159) endothelial cell-cell adhesion(GO:0071603)
0.0 0.1 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.5 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.2 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.1 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 0.3 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 0.1 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.1 GO:0070445 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0 0.2 GO:0019532 oxalate transport(GO:0019532)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:1904386 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.0 0.1 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.2 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.1 GO:0006983 ER overload response(GO:0006983)
0.0 0.6 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.0 GO:1903413 cellular response to bile acid(GO:1903413)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.1 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.0 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.0 0.2 GO:0046325 negative regulation of glucose import(GO:0046325)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.1 GO:0071344 diphosphate metabolic process(GO:0071344)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.3 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.2 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0 0.2 GO:0016081 synaptic vesicle docking(GO:0016081)
0.0 0.4 GO:0007567 parturition(GO:0007567)
0.0 0.1 GO:0098501 polynucleotide dephosphorylation(GO:0098501)
0.0 0.3 GO:0030728 ovulation(GO:0030728)
0.0 0.8 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.3 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.1 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.0 0.0 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.3 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 1.4 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.2 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0 0.1 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.0 0.1 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.2 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.3 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.1 GO:0010166 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.4 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 0.4 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.1 0.4 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 0.4 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.1 0.2 GO:0071159 NF-kappaB complex(GO:0071159)
0.1 0.3 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.2 GO:0098855 HCN channel complex(GO:0098855)
0.1 0.3 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 0.2 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.1 0.3 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.1 0.5 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.6 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 1.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.5 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.2 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.2 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.5 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.1 GO:0072534 perineuronal net(GO:0072534)
0.0 0.2 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.0 1.7 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.1 GO:0005606 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260)
0.0 0.8 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0005873 plus-end kinesin complex(GO:0005873)
0.0 0.7 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.6 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.3 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.1 GO:0070470 plasma membrane respiratory chain(GO:0070470)
0.0 0.2 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.1 GO:0036128 CatSper complex(GO:0036128)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 3.0 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.8 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.2 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.1 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.1 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.8 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.3 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.9 GO:0045095 keratin filament(GO:0045095)
0.0 0.4 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.8 GO:0005871 kinesin complex(GO:0005871)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.4 1.1 GO:0042007 interleukin-18 binding(GO:0042007)
0.2 0.5 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.1 0.7 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.1 0.4 GO:0015131 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.1 0.4 GO:0017130 poly(C) RNA binding(GO:0017130)
0.1 1.4 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.7 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.1 0.4 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.1 0.3 GO:0017129 triglyceride binding(GO:0017129)
0.1 0.3 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.1 0.3 GO:0001855 complement component C4b binding(GO:0001855)
0.1 2.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.3 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.3 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.1 0.4 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1 0.5 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 0.7 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 0.5 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.5 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.3 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.5 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.2 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.1 0.6 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.1 0.2 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.1 0.7 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 0.2 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.2 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.1 0.2 GO:0008478 pyridoxal kinase activity(GO:0008478) lithium ion binding(GO:0031403)
0.1 0.3 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.4 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.4 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.3 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.3 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.3 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.1 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.2 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.9 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.3 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.4 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.1 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.2 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.0 0.1 GO:0043337 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.0 0.1 GO:0015141 succinate transmembrane transporter activity(GO:0015141)
0.0 0.2 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.5 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.3 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.2 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.3 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.1 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.2 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.0 0.3 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.2 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.2 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.1 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 0.7 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.2 GO:0035473 lipase binding(GO:0035473)
0.0 0.1 GO:1990259 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.0 0.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.3 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 0.5 GO:0060229 lipase activator activity(GO:0060229)
0.0 0.1 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.0 0.1 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 1.0 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.1 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.2 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.3 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.7 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.2 GO:0031433 telethonin binding(GO:0031433)
0.0 0.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.0 0.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 1.0 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.6 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.3 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.0 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.3 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.4 GO:0030553 cGMP binding(GO:0030553)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.5 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.7 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.1 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.1 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.2 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.3 GO:0008494 translation activator activity(GO:0008494)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.0 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.6 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.3 GO:0005521 lamin binding(GO:0005521)
0.0 0.3 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.2 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.2 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.6 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.3 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.3 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.9 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.6 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.1 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.5 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 0.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.8 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.3 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.1 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 0.8 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 1.5 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 3.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.7 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.7 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.8 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.6 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.5 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.7 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.5 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.5 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 2.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.3 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.3 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.2 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 1.0 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 1.1 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.4 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.1 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 1.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.4 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.3 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.4 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.1 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins