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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for NR6A1

Z-value: 0.64

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Transcription factors associated with NR6A1

Gene Symbol Gene ID Gene Info
NR6A1
ENSG00000148200.12 nuclear receptor subfamily 6 group A member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR6A1hg19_v2_chr9_-_127533582_1275336150.611.2e-03Click!

Activity profile of NR6A1 motif

Sorted Z-values of NR6A1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_76071805 0.96 ENST00000539311.1
FLVCR2
feline leukemia virus subgroup C cellular receptor family, member 2
chr19_-_43586820 0.75 ENST00000406487.1
PSG2
pregnancy specific beta-1-glycoprotein 2
chr19_+_41699135 0.71 ENST00000542619.1
ENST00000600561.1
CYP2S1
cytochrome P450, family 2, subfamily S, polypeptide 1
chr19_+_41698927 0.62 ENST00000310054.4
CYP2S1
cytochrome P450, family 2, subfamily S, polypeptide 1
chr21_+_43639211 0.58 ENST00000450121.1
ENST00000398449.3
ENST00000361802.2
ABCG1
ATP-binding cassette, sub-family G (WHITE), member 1
chr17_-_46799872 0.51 ENST00000290294.3
PRAC1
prostate cancer susceptibility candidate 1
chr6_-_160166218 0.51 ENST00000537657.1
SOD2
superoxide dismutase 2, mitochondrial
chr11_-_35287243 0.49 ENST00000464522.2
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr7_-_142232071 0.47 ENST00000390364.3
TRBV10-1
T cell receptor beta variable 10-1(gene/pseudogene)
chr12_+_60058458 0.43 ENST00000548610.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr10_+_116853201 0.41 ENST00000527407.1
ATRNL1
attractin-like 1
chr1_+_78511586 0.41 ENST00000370759.3
GIPC2
GIPC PDZ domain containing family, member 2
chr11_-_108464465 0.41 ENST00000525344.1
EXPH5
exophilin 5
chr9_-_38069208 0.40 ENST00000377707.3
ENST00000377700.4
SHB
Src homology 2 domain containing adaptor protein B
chr7_-_108168580 0.40 ENST00000453085.1
PNPLA8
patatin-like phospholipase domain containing 8
chr2_+_201994208 0.39 ENST00000440180.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr15_+_76629064 0.38 ENST00000290759.4
ISL2
ISL LIM homeobox 2
chr1_-_161102421 0.38 ENST00000490843.2
ENST00000368006.3
ENST00000392188.1
ENST00000545495.1
DEDD
death effector domain containing
chr11_+_34643600 0.37 ENST00000530286.1
ENST00000533754.1
EHF
ets homologous factor
chr10_+_81107271 0.37 ENST00000448165.1
PPIF
peptidylprolyl isomerase F
chr19_-_43382142 0.37 ENST00000597058.1
PSG1
pregnancy specific beta-1-glycoprotein 1
chr1_+_212738676 0.36 ENST00000366981.4
ENST00000366987.2
ATF3
activating transcription factor 3
chr1_-_161102367 0.36 ENST00000464113.1
DEDD
death effector domain containing
chr6_+_84743436 0.35 ENST00000257776.4
MRAP2
melanocortin 2 receptor accessory protein 2
chr16_-_75498308 0.35 ENST00000569540.1
TMEM170A
transmembrane protein 170A
chr11_-_11747257 0.35 ENST00000601641.1
AC131935.1
AC131935.1
chr17_-_56494713 0.34 ENST00000407977.2
RNF43
ring finger protein 43
chr10_+_124030819 0.33 ENST00000260723.4
ENST00000368994.2
BTBD16
BTB (POZ) domain containing 16
chr11_+_66188475 0.33 ENST00000311034.2
NPAS4
neuronal PAS domain protein 4
chr3_-_139396560 0.33 ENST00000514703.1
ENST00000511444.1
NMNAT3
nicotinamide nucleotide adenylyltransferase 3
chr13_-_114898016 0.33 ENST00000542651.1
ENST00000334062.7
RASA3
RAS p21 protein activator 3
chr1_-_202679535 0.32 ENST00000367268.4
SYT2
synaptotagmin II
chr5_+_140749803 0.31 ENST00000576222.1
PCDHGB3
protocadherin gamma subfamily B, 3
chr8_-_102275131 0.31 ENST00000523121.1
KB-1410C5.2
KB-1410C5.2
chr7_+_150521691 0.31 ENST00000493429.1
AOC1
amine oxidase, copper containing 1
chr8_-_141645645 0.30 ENST00000519980.1
ENST00000220592.5
AGO2
argonaute RISC catalytic component 2
chr19_+_53761545 0.30 ENST00000341702.3
VN1R2
vomeronasal 1 receptor 2
chr17_-_37309480 0.29 ENST00000539608.1
PLXDC1
plexin domain containing 1
chr8_-_17555164 0.28 ENST00000297488.6
MTUS1
microtubule associated tumor suppressor 1
chr16_-_75498553 0.27 ENST00000569276.1
ENST00000357613.4
ENST00000561878.1
ENST00000566980.1
ENST00000567194.1
TMEM170A
RP11-77K12.1
transmembrane protein 170A
Uncharacterized protein
chr4_-_159094194 0.27 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
FAM198B
family with sequence similarity 198, member B
chr8_-_27472198 0.27 ENST00000519472.1
ENST00000523589.1
ENST00000522413.1
ENST00000523396.1
ENST00000560366.1
CLU
clusterin
chr19_+_15160130 0.27 ENST00000427043.3
CASP14
caspase 14, apoptosis-related cysteine peptidase
chr7_+_37960163 0.26 ENST00000199448.4
ENST00000559325.1
ENST00000423717.1
EPDR1
ependymin related 1
chr19_-_43422019 0.26 ENST00000402603.4
ENST00000594375.1
PSG6
pregnancy specific beta-1-glycoprotein 6
chr5_-_156486120 0.26 ENST00000522693.1
HAVCR1
hepatitis A virus cellular receptor 1
chr17_-_37308824 0.26 ENST00000415163.1
ENST00000441877.1
ENST00000444911.2
PLXDC1
plexin domain containing 1
chr3_+_37284824 0.26 ENST00000431105.1
GOLGA4
golgin A4
chr2_-_25564750 0.25 ENST00000321117.5
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr1_+_107682629 0.25 ENST00000370074.4
ENST00000370073.2
ENST00000370071.2
ENST00000542803.1
ENST00000370061.3
ENST00000370072.3
ENST00000370070.2
NTNG1
netrin G1
chr14_+_22670455 0.25 ENST00000390460.1
TRAV26-2
T cell receptor alpha variable 26-2
chr17_-_71410794 0.25 ENST00000424778.1
SDK2
sidekick cell adhesion molecule 2
chr11_+_111789580 0.25 ENST00000278601.5
C11orf52
chromosome 11 open reading frame 52
chr9_-_14314066 0.24 ENST00000397575.3
NFIB
nuclear factor I/B
chr17_+_66509019 0.24 ENST00000585981.1
ENST00000589480.1
ENST00000585815.1
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr10_+_116853091 0.24 ENST00000526946.1
ATRNL1
attractin-like 1
chr9_+_75136717 0.24 ENST00000297784.5
TMC1
transmembrane channel-like 1
chr3_+_114012819 0.24 ENST00000383671.3
TIGIT
T cell immunoreceptor with Ig and ITIM domains
chr13_+_23755099 0.24 ENST00000537476.1
SGCG
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chr19_-_58864848 0.24 ENST00000263100.3
A1BG
alpha-1-B glycoprotein
chr12_-_91574142 0.24 ENST00000547937.1
DCN
decorin
chr2_+_234296792 0.23 ENST00000409813.3
DGKD
diacylglycerol kinase, delta 130kDa
chr1_-_161207875 0.23 ENST00000512372.1
ENST00000437437.2
ENST00000442691.2
ENST00000412844.2
ENST00000428574.2
ENST00000505005.1
ENST00000508740.1
ENST00000508387.1
ENST00000504010.1
ENST00000511676.1
ENST00000502985.1
ENST00000367981.3
ENST00000515621.1
ENST00000511944.1
ENST00000511748.1
ENST00000367984.4
ENST00000367985.3
NR1I3
nuclear receptor subfamily 1, group I, member 3
chr3_-_156840776 0.23 ENST00000471357.1
LINC00880
long intergenic non-protein coding RNA 880
chr12_-_24737089 0.23 ENST00000483544.1
LINC00477
long intergenic non-protein coding RNA 477
chr17_-_79817091 0.23 ENST00000570907.1
P4HB
prolyl 4-hydroxylase, beta polypeptide
chr12_+_69186125 0.23 ENST00000399333.3
AC124890.1
HCG1774533, isoform CRA_a; PRO2268; Uncharacterized protein
chr13_+_23755054 0.23 ENST00000218867.3
SGCG
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chr12_-_109219937 0.22 ENST00000546697.1
SSH1
slingshot protein phosphatase 1
chr16_+_31366455 0.22 ENST00000268296.4
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr2_-_175711133 0.22 ENST00000409597.1
ENST00000413882.1
CHN1
chimerin 1
chr11_+_62009653 0.22 ENST00000244926.3
SCGB1D2
secretoglobin, family 1D, member 2
chr21_+_10862622 0.21 ENST00000302092.5
ENST00000559480.1
IGHV1OR21-1
immunoglobulin heavy variable 1/OR21-1 (non-functional)
chr17_+_7942424 0.21 ENST00000573359.1
ALOX15B
arachidonate 15-lipoxygenase, type B
chr16_-_420338 0.21 ENST00000450882.1
ENST00000441883.1
ENST00000447696.1
ENST00000389675.2
MRPL28
mitochondrial ribosomal protein L28
chr17_-_2614927 0.20 ENST00000435359.1
CLUH
clustered mitochondria (cluA/CLU1) homolog
chr17_+_7531281 0.20 ENST00000575729.1
ENST00000340624.5
SHBG
sex hormone-binding globulin
chr11_+_65190245 0.20 ENST00000499732.1
ENST00000501122.2
ENST00000601801.1
NEAT1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr7_+_72349920 0.20 ENST00000395270.1
ENST00000446813.1
ENST00000257622.4
POM121
POM121 transmembrane nucleoporin
chr12_-_7261772 0.20 ENST00000545280.1
ENST00000543933.1
ENST00000545337.1
ENST00000544702.1
ENST00000266542.4
C1RL
complement component 1, r subcomponent-like
chr20_+_31619454 0.20 ENST00000349552.1
BPIFB6
BPI fold containing family B, member 6
chr11_-_104480019 0.20 ENST00000536529.1
ENST00000545630.1
ENST00000538641.1
RP11-886D15.1
RP11-886D15.1
chr6_-_31697977 0.19 ENST00000375787.2
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr16_-_2836606 0.19 ENST00000571674.1
ENST00000293851.5
ENST00000576886.1
PRSS33
protease, serine, 33
chr16_-_420514 0.19 ENST00000199706.8
MRPL28
mitochondrial ribosomal protein L28
chr19_+_8953269 0.19 ENST00000305625.2
MBD3L1
methyl-CpG binding domain protein 3-like 1
chr8_-_72268889 0.19 ENST00000388742.4
EYA1
eyes absent homolog 1 (Drosophila)
chr1_-_184943610 0.19 ENST00000367511.3
FAM129A
family with sequence similarity 129, member A
chr22_+_40390930 0.19 ENST00000333407.6
FAM83F
family with sequence similarity 83, member F
chr22_+_45680822 0.18 ENST00000216211.4
ENST00000396082.2
UPK3A
uroplakin 3A
chr19_-_7293942 0.18 ENST00000341500.5
ENST00000302850.5
INSR
insulin receptor
chr5_+_55147205 0.18 ENST00000396836.2
ENST00000396834.1
ENST00000447346.2
ENST00000359040.5
IL31RA
interleukin 31 receptor A
chr15_-_20170354 0.18 ENST00000338912.5
IGHV1OR15-9
immunoglobulin heavy variable 1/OR15-9 (non-functional)
chrX_+_54466829 0.18 ENST00000375151.4
TSR2
TSR2, 20S rRNA accumulation, homolog (S. cerevisiae)
chr1_-_112032284 0.18 ENST00000414219.1
ADORA3
adenosine A3 receptor
chr11_+_113185533 0.18 ENST00000393020.1
TTC12
tetratricopeptide repeat domain 12
chr3_-_139396801 0.18 ENST00000413939.2
ENST00000339837.5
ENST00000512391.1
NMNAT3
nicotinamide nucleotide adenylyltransferase 3
chr12_+_9980069 0.18 ENST00000354855.3
ENST00000324214.4
ENST00000279544.3
KLRF1
killer cell lectin-like receptor subfamily F, member 1
chr11_-_124190184 0.17 ENST00000357438.2
OR8D2
olfactory receptor, family 8, subfamily D, member 2
chr18_+_11751493 0.17 ENST00000269162.5
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr3_-_139396853 0.17 ENST00000406164.1
ENST00000406824.1
NMNAT3
nicotinamide nucleotide adenylyltransferase 3
chr1_+_45212051 0.17 ENST00000372222.3
KIF2C
kinesin family member 2C
chr9_-_111619239 0.17 ENST00000374667.3
ACTL7B
actin-like 7B
chr18_+_616672 0.17 ENST00000338387.7
CLUL1
clusterin-like 1 (retinal)
chr18_+_616711 0.17 ENST00000579494.1
CLUL1
clusterin-like 1 (retinal)
chr17_-_8198636 0.16 ENST00000577745.1
ENST00000579192.1
ENST00000396278.1
SLC25A35
solute carrier family 25, member 35
chr16_-_30122717 0.16 ENST00000566613.1
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr5_-_138725594 0.16 ENST00000302125.8
MZB1
marginal zone B and B1 cell-specific protein
chr1_-_161207953 0.16 ENST00000367982.4
NR1I3
nuclear receptor subfamily 1, group I, member 3
chr5_-_138725560 0.16 ENST00000412103.2
ENST00000457570.2
MZB1
marginal zone B and B1 cell-specific protein
chr5_-_41213607 0.16 ENST00000337836.5
ENST00000433294.1
C6
complement component 6
chr19_+_51376505 0.16 ENST00000325321.3
ENST00000600690.1
ENST00000391810.2
ENST00000358049.4
KLK2
kallikrein-related peptidase 2
chr18_+_11751466 0.16 ENST00000535121.1
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chrX_-_118827113 0.16 ENST00000394617.2
SEPT6
septin 6
chr9_-_140115775 0.15 ENST00000391553.1
ENST00000392827.1
RNF208
ring finger protein 208
chr22_-_24181174 0.15 ENST00000318109.7
ENST00000406855.3
ENST00000404056.1
ENST00000476077.1
DERL3
derlin 3
chr1_-_161208013 0.15 ENST00000515452.1
ENST00000367983.4
NR1I3
nuclear receptor subfamily 1, group I, member 3
chr9_-_39239171 0.15 ENST00000358144.2
CNTNAP3
contactin associated protein-like 3
chr18_+_23713808 0.15 ENST00000415576.2
ENST00000343848.6
ENST00000308268.6
PSMA8
proteasome (prosome, macropain) subunit, alpha type, 8
chr17_-_27503770 0.15 ENST00000533112.1
MYO18A
myosin XVIIIA
chr2_-_26467465 0.15 ENST00000457468.2
HADHA
hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
chr10_+_114710516 0.15 ENST00000542695.1
ENST00000346198.4
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr5_-_135231516 0.15 ENST00000274520.1
IL9
interleukin 9
chr1_+_45212074 0.15 ENST00000372217.1
KIF2C
kinesin family member 2C
chr12_+_10366016 0.15 ENST00000546017.1
ENST00000535576.1
ENST00000539170.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr9_-_14313641 0.15 ENST00000380953.1
NFIB
nuclear factor I/B
chrX_+_103031758 0.14 ENST00000303958.2
ENST00000361621.2
PLP1
proteolipid protein 1
chr7_+_94536898 0.14 ENST00000433360.1
ENST00000340694.4
ENST00000424654.1
PPP1R9A
protein phosphatase 1, regulatory subunit 9A
chr7_-_56160625 0.14 ENST00000446428.1
ENST00000432123.1
ENST00000452681.2
ENST00000537360.1
PHKG1
phosphorylase kinase, gamma 1 (muscle)
chr3_-_113464906 0.14 ENST00000477813.1
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr13_+_111766897 0.14 ENST00000317133.5
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr8_-_72268968 0.14 ENST00000388740.3
EYA1
eyes absent homolog 1 (Drosophila)
chr11_-_108464321 0.14 ENST00000265843.4
EXPH5
exophilin 5
chr7_+_102004322 0.14 ENST00000496391.1
PRKRIP1
PRKR interacting protein 1 (IL11 inducible)
chr3_+_113465866 0.13 ENST00000273398.3
ENST00000538620.1
ENST00000496747.1
ENST00000475322.1
ATP6V1A
ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr17_+_32612687 0.13 ENST00000305869.3
CCL11
chemokine (C-C motif) ligand 11
chr11_-_73720122 0.13 ENST00000426995.2
UCP3
uncoupling protein 3 (mitochondrial, proton carrier)
chr5_+_169780485 0.13 ENST00000377360.4
KCNIP1
Kv channel interacting protein 1
chr22_-_50217981 0.13 ENST00000457780.2
BRD1
bromodomain containing 1
chr1_+_29213584 0.13 ENST00000343067.4
ENST00000356093.2
ENST00000398863.2
ENST00000373800.3
ENST00000349460.4
EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr3_+_73045936 0.13 ENST00000356692.5
ENST00000488810.1
ENST00000394284.3
ENST00000295862.9
ENST00000495566.1
PPP4R2
protein phosphatase 4, regulatory subunit 2
chr21_+_42694732 0.13 ENST00000398646.3
FAM3B
family with sequence similarity 3, member B
chr22_+_42372764 0.13 ENST00000396426.3
ENST00000406029.1
SEPT3
septin 3
chr6_-_25874440 0.13 ENST00000361703.6
ENST00000397060.4
SLC17A3
solute carrier family 17 (organic anion transporter), member 3
chr19_-_43269809 0.13 ENST00000406636.3
ENST00000404209.4
ENST00000306511.4
PSG8
pregnancy specific beta-1-glycoprotein 8
chr9_-_14314518 0.13 ENST00000397581.2
NFIB
nuclear factor I/B
chrY_+_16636354 0.13 ENST00000339174.5
NLGN4Y
neuroligin 4, Y-linked
chr2_-_60780607 0.13 ENST00000537768.1
ENST00000335712.6
ENST00000356842.4
BCL11A
B-cell CLL/lymphoma 11A (zinc finger protein)
chr9_+_976964 0.12 ENST00000190165.2
DMRT3
doublesex and mab-3 related transcription factor 3
chr2_+_26568965 0.12 ENST00000260585.7
ENST00000447170.1
EPT1
ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)
chr19_-_8373173 0.12 ENST00000537716.2
ENST00000301458.5
CD320
CD320 molecule
chr17_-_40729681 0.12 ENST00000590760.1
ENST00000587209.1
ENST00000393795.3
ENST00000253789.5
PSMC3IP
PSMC3 interacting protein
chr7_-_69062391 0.12 ENST00000436600.2
RP5-942I16.1
RP5-942I16.1
chr6_+_31620191 0.12 ENST00000375918.2
ENST00000375920.4
APOM
apolipoprotein M
chr8_-_27468842 0.12 ENST00000523500.1
CLU
clusterin
chr17_-_39093672 0.12 ENST00000209718.3
ENST00000436344.3
ENST00000485751.1
KRT23
keratin 23 (histone deacetylase inducible)
chr17_-_7531121 0.12 ENST00000573566.1
ENST00000269298.5
SAT2
spermidine/spermine N1-acetyltransferase family member 2
chr19_-_22193706 0.12 ENST00000597040.1
ZNF208
zinc finger protein 208
chrX_+_103031421 0.12 ENST00000433491.1
ENST00000418604.1
ENST00000443502.1
PLP1
proteolipid protein 1
chr12_+_50017184 0.12 ENST00000548825.2
PRPF40B
PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr2_+_54558004 0.12 ENST00000405749.1
ENST00000398634.2
ENST00000447328.1
C2orf73
chromosome 2 open reading frame 73
chr5_-_146258291 0.12 ENST00000394411.4
ENST00000453001.1
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr6_+_25652432 0.12 ENST00000377961.2
SCGN
secretagogin, EF-hand calcium binding protein
chr2_+_152266604 0.11 ENST00000430328.2
RIF1
RAP1 interacting factor homolog (yeast)
chr8_-_145701718 0.11 ENST00000377317.4
FOXH1
forkhead box H1
chr9_-_21305312 0.11 ENST00000259555.4
IFNA5
interferon, alpha 5
chr19_-_43244610 0.11 ENST00000595140.1
ENST00000327495.5
PSG3
pregnancy specific beta-1-glycoprotein 3
chr22_-_50218452 0.11 ENST00000216267.8
BRD1
bromodomain containing 1
chr14_-_106471723 0.11 ENST00000390595.2
IGHV1-3
immunoglobulin heavy variable 1-3
chr16_-_84538218 0.11 ENST00000562447.1
ENST00000565765.1
ENST00000535580.1
ENST00000343629.6
TLDC1
TBC/LysM-associated domain containing 1
chr5_+_72143988 0.11 ENST00000506351.2
TNPO1
transportin 1
chr11_-_78052923 0.11 ENST00000340149.2
GAB2
GRB2-associated binding protein 2
chr2_+_152266392 0.10 ENST00000444746.2
ENST00000453091.2
ENST00000428287.2
ENST00000433166.2
ENST00000420714.3
ENST00000243326.5
ENST00000414861.2
RIF1
RAP1 interacting factor homolog (yeast)
chr8_-_16043780 0.10 ENST00000445506.2
MSR1
macrophage scavenger receptor 1
chr3_-_139396787 0.10 ENST00000296202.7
ENST00000509291.1
NMNAT3
nicotinamide nucleotide adenylyltransferase 3
chr17_-_15587602 0.10 ENST00000416464.2
ENST00000578237.1
ENST00000581200.1
TRIM16
tripartite motif containing 16
chr19_+_11455900 0.10 ENST00000588790.1
CCDC159
coiled-coil domain containing 159
chr4_-_170948361 0.10 ENST00000393702.3
MFAP3L
microfibrillar-associated protein 3-like
chr10_-_76995675 0.10 ENST00000469299.1
COMTD1
catechol-O-methyltransferase domain containing 1
chr14_-_106539557 0.10 ENST00000390599.2
IGHV1-8
immunoglobulin heavy variable 1-8
chr1_-_161207986 0.10 ENST00000506209.1
ENST00000367980.2
NR1I3
nuclear receptor subfamily 1, group I, member 3
chr1_+_92417716 0.10 ENST00000402388.1
BRDT
bromodomain, testis-specific
chr7_+_31569365 0.10 ENST00000454513.1
ENST00000451887.2
CCDC129
coiled-coil domain containing 129
chr11_-_33743952 0.10 ENST00000534312.1
CD59
CD59 molecule, complement regulatory protein
chr7_-_75401513 0.10 ENST00000005180.4
CCL26
chemokine (C-C motif) ligand 26
chr7_-_95225768 0.10 ENST00000005178.5
PDK4
pyruvate dehydrogenase kinase, isozyme 4
chr10_+_11207438 0.10 ENST00000609692.1
ENST00000354897.3
CELF2
CUGBP, Elav-like family member 2
chrX_-_46187069 0.10 ENST00000446884.1
RP1-30G7.2
RP1-30G7.2
chr6_+_28109703 0.10 ENST00000457389.2
ENST00000330236.6
ZKSCAN8
zinc finger with KRAB and SCAN domains 8
chr16_-_21170762 0.10 ENST00000261383.3
ENST00000415178.1
DNAH3
dynein, axonemal, heavy chain 3
chrX_+_56100757 0.10 ENST00000433279.1
AL353698.1
Uncharacterized protein
chr9_-_122131696 0.10 ENST00000373964.2
ENST00000265922.3
BRINP1
bone morphogenetic protein/retinoic acid inducible neural-specific 1
chr10_-_50396425 0.10 ENST00000374148.1
C10orf128
chromosome 10 open reading frame 128
chrX_+_23018058 0.10 ENST00000327968.5
DDX53
DEAD (Asp-Glu-Ala-Asp) box polypeptide 53
chr11_+_118398178 0.10 ENST00000302783.4
ENST00000539546.1
TTC36
tetratricopeptide repeat domain 36
chr19_-_43690674 0.10 ENST00000342951.6
ENST00000366175.3
PSG5
pregnancy specific beta-1-glycoprotein 5
chr5_-_176836577 0.09 ENST00000253496.3
F12
coagulation factor XII (Hageman factor)
chr15_-_22082822 0.09 ENST00000439682.1
POTEB
POTE ankyrin domain family, member B
chr8_-_87081926 0.09 ENST00000276616.2
PSKH2
protein serine kinase H2
chr22_+_23229960 0.09 ENST00000526893.1
ENST00000532223.2
ENST00000531372.1
IGLL5
immunoglobulin lambda-like polypeptide 5

Network of associatons between targets according to the STRING database.

First level regulatory network of NR6A1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0055099 detection of endogenous stimulus(GO:0009726) response to high density lipoprotein particle(GO:0055099)
0.1 0.4 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.1 0.8 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.1 0.4 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.1 0.4 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.1 0.4 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.5 GO:0001315 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.1 0.4 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 0.3 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.1 0.5 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 0.2 GO:1904719 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.1 1.0 GO:0015886 heme transport(GO:0015886)
0.1 0.3 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.4 GO:0061518 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 0.3 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.1 0.5 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 0.2 GO:1904799 negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.1 0.4 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 0.3 GO:0071504 cellular response to heparin(GO:0071504)
0.1 1.3 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.1 GO:1904048 regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.0 0.2 GO:1990535 transformation of host cell by virus(GO:0019087) neuron projection maintenance(GO:1990535)
0.0 0.1 GO:0035962 response to interleukin-13(GO:0035962)
0.0 0.3 GO:0035087 siRNA loading onto RISC involved in RNA interference(GO:0035087) mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.3 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.2 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.0 0.2 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.4 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.1 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.0 0.3 GO:0019236 response to pheromone(GO:0019236)
0.0 0.2 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.3 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.1 GO:0051039 histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.0 0.3 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.1 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.1 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
0.0 0.1 GO:0034444 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.0 0.2 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.1 GO:0009447 putrescine catabolic process(GO:0009447)
0.0 0.6 GO:0051292 nuclear pore complex assembly(GO:0051292) endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.1 GO:0050894 determination of affect(GO:0050894)
0.0 0.2 GO:0060157 urinary bladder development(GO:0060157)
0.0 0.1 GO:0031296 B cell costimulation(GO:0031296)
0.0 0.1 GO:0043105 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.0 0.3 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.5 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0072023 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.0 0.2 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.2 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.1 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) myotome development(GO:0061055)
0.0 0.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.1 GO:0007343 egg activation(GO:0007343)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.2 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.1 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.0 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.0 0.0 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.3 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.3 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.2 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 0.1 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.0 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 0.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.1 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.2 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.0 GO:0060510 Type II pneumocyte differentiation(GO:0060510)
0.0 0.0 GO:0021779 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.2 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.1 GO:0061760 antifungal innate immune response(GO:0061760)
0.0 0.0 GO:1904815 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837) negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.0 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 0.2 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 0.5 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.7 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.1 GO:0032173 septin ring(GO:0005940) septin collar(GO:0032173)
0.0 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.2 GO:0001940 male pronucleus(GO:0001940)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.3 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.2 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.4 GO:0097342 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.2 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0033011 perinuclear theca(GO:0033011)
0.0 0.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.3 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.1 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.1 GO:0000322 storage vacuole(GO:0000322)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.0 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.5 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:0001741 XY body(GO:0001741)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.2 0.6 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.1 0.8 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.1 0.6 GO:0004882 androgen receptor activity(GO:0004882)
0.1 0.4 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.3 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 0.3 GO:0098808 mRNA cap binding(GO:0098808)
0.1 0.3 GO:0031780 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.1 1.0 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.2 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.1 0.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.5 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.2 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0015235 cobalamin transporter activity(GO:0015235)
0.0 0.2 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.4 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.3 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.3 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.2 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.3 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.1 GO:0031877 somatostatin receptor binding(GO:0031877)
0.0 0.2 GO:0005497 androgen binding(GO:0005497)
0.0 0.1 GO:0017057 glucose-6-phosphate dehydrogenase activity(GO:0004345) 6-phosphogluconolactonase activity(GO:0017057)
0.0 0.2 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.1 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.6 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.1 GO:0019961 interferon binding(GO:0019961)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.1 GO:0004913 interleukin-4 receptor activity(GO:0004913) interleukin-7 receptor activity(GO:0004917)
0.0 0.2 GO:0043559 insulin binding(GO:0043559)
0.0 0.1 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.7 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.0 0.1 GO:0032089 NACHT domain binding(GO:0032089)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.0 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.2 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.3 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.0 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.0 0.2 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.0 GO:0005042 netrin receptor activity(GO:0005042)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.1 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.6 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.3 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.5 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.3 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity