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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for OLIG2_NEUROD1_ATOH1

Z-value: 0.83

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Transcription factors associated with OLIG2_NEUROD1_ATOH1

Gene Symbol Gene ID Gene Info
OLIG2
ENSG00000205927.4 oligodendrocyte transcription factor 2
NEUROD1
ENSG00000162992.3 neuronal differentiation 1
ATOH1
ENSG00000172238.3 atonal bHLH transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NEUROD1hg19_v2_chr2_-_182545603_1825456030.367.7e-02Click!
OLIG2hg19_v2_chr21_+_34398153_34398250-0.232.7e-01Click!
ATOH1hg19_v2_chr4_+_94750014_947500420.193.7e-01Click!

Activity profile of OLIG2_NEUROD1_ATOH1 motif

Sorted Z-values of OLIG2_NEUROD1_ATOH1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_7005785 3.44 ENST00000256722.5
ENST00000404168.1
ENST00000458098.1
CMPK2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr13_-_33780133 2.66 ENST00000399365.3
STARD13
StAR-related lipid transfer (START) domain containing 13
chr12_+_113416191 2.58 ENST00000342315.4
ENST00000392583.2
OAS2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr8_-_135522425 1.46 ENST00000521673.1
ZFAT
zinc finger and AT hook domain containing
chr7_-_41742697 1.40 ENST00000242208.4
INHBA
inhibin, beta A
chr4_+_90033968 1.26 ENST00000317005.2
TIGD2
tigger transposable element derived 2
chr2_-_225811747 1.24 ENST00000409592.3
DOCK10
dedicator of cytokinesis 10
chr8_+_54764346 1.21 ENST00000297313.3
ENST00000344277.6
RGS20
regulator of G-protein signaling 20
chr5_+_135364584 1.20 ENST00000442011.2
ENST00000305126.8
TGFBI
transforming growth factor, beta-induced, 68kDa
chr12_+_113416265 1.08 ENST00000449768.2
OAS2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr11_+_44587141 1.05 ENST00000227155.4
ENST00000342935.3
ENST00000532544.1
CD82
CD82 molecule
chr16_-_69385681 1.04 ENST00000288025.3
TMED6
transmembrane emp24 protein transport domain containing 6
chr19_-_4338783 0.97 ENST00000601482.1
ENST00000600324.1
STAP2
signal transducing adaptor family member 2
chr10_-_62149433 0.96 ENST00000280772.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr5_-_59481406 0.87 ENST00000546160.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr6_+_53948328 0.87 ENST00000370876.2
MLIP
muscular LMNA-interacting protein
chr16_+_83932684 0.86 ENST00000262430.4
MLYCD
malonyl-CoA decarboxylase
chr12_+_32655110 0.86 ENST00000546442.1
ENST00000583694.1
FGD4
FYVE, RhoGEF and PH domain containing 4
chrX_-_11445856 0.84 ENST00000380736.1
ARHGAP6
Rho GTPase activating protein 6
chr19_-_39368887 0.83 ENST00000340740.3
ENST00000591812.1
RINL
Ras and Rab interactor-like
chr9_-_35111420 0.81 ENST00000378557.1
FAM214B
family with sequence similarity 214, member B
chr11_+_71249071 0.81 ENST00000398534.3
KRTAP5-8
keratin associated protein 5-8
chr12_+_6309517 0.79 ENST00000382519.4
ENST00000009180.4
CD9
CD9 molecule
chr1_+_172422026 0.79 ENST00000367725.4
C1orf105
chromosome 1 open reading frame 105
chr16_+_56623433 0.77 ENST00000570176.1
MT3
metallothionein 3
chr12_+_69201923 0.76 ENST00000462284.1
ENST00000258149.5
ENST00000356290.4
ENST00000540827.1
ENST00000428863.2
ENST00000393412.3
MDM2
MDM2 oncogene, E3 ubiquitin protein ligase
chr12_+_6309963 0.76 ENST00000382515.2
CD9
CD9 molecule
chr11_+_20044096 0.74 ENST00000533917.1
NAV2
neuron navigator 2
chr1_-_171621815 0.69 ENST00000037502.6
MYOC
myocilin, trabecular meshwork inducible glucocorticoid response
chr11_+_76494253 0.62 ENST00000333090.4
TSKU
tsukushi, small leucine rich proteoglycan
chr9_+_72658490 0.61 ENST00000377182.4
MAMDC2
MAM domain containing 2
chr5_-_180632293 0.60 ENST00000334421.5
TRIM7
tripartite motif containing 7
chr10_-_61513201 0.59 ENST00000414264.1
ENST00000594536.1
LINC00948
long intergenic non-protein coding RNA 948
chr11_-_14913765 0.58 ENST00000334636.5
CYP2R1
cytochrome P450, family 2, subfamily R, polypeptide 1
chr12_+_117348742 0.57 ENST00000309909.5
ENST00000455858.2
FBXW8
F-box and WD repeat domain containing 8
chr11_+_7597639 0.57 ENST00000533792.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr16_-_84273304 0.54 ENST00000308251.4
ENST00000568181.1
KCNG4
potassium voltage-gated channel, subfamily G, member 4
chr12_+_4382917 0.54 ENST00000261254.3
CCND2
cyclin D2
chr10_-_121296045 0.53 ENST00000392865.1
RGS10
regulator of G-protein signaling 10
chr19_+_35521616 0.52 ENST00000595652.1
SCN1B
sodium channel, voltage-gated, type I, beta subunit
chr16_+_30386098 0.52 ENST00000322861.7
MYLPF
myosin light chain, phosphorylatable, fast skeletal muscle
chr2_-_154335300 0.52 ENST00000325926.3
RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chr19_+_36249057 0.50 ENST00000301165.5
ENST00000536950.1
ENST00000537459.1
ENST00000421853.2
C19orf55
chromosome 19 open reading frame 55
chr21_+_30502806 0.48 ENST00000399928.1
ENST00000399926.1
MAP3K7CL
MAP3K7 C-terminal like
chr1_-_39339777 0.48 ENST00000397572.2
MYCBP
MYC binding protein
chr3_-_52486841 0.48 ENST00000496590.1
TNNC1
troponin C type 1 (slow)
chr7_+_143078652 0.47 ENST00000354434.4
ENST00000449423.2
ZYX
zyxin
chr9_-_140351928 0.47 ENST00000339554.3
NSMF
NMDA receptor synaptonuclear signaling and neuronal migration factor
chr3_-_45267760 0.46 ENST00000503771.1
TMEM158
transmembrane protein 158 (gene/pseudogene)
chr11_-_5173599 0.46 ENST00000328942.1
OR52A1
olfactory receptor, family 52, subfamily A, member 1
chrX_-_108868390 0.46 ENST00000372101.2
KCNE1L
KCNE1-like
chr2_-_163100045 0.45 ENST00000188790.4
FAP
fibroblast activation protein, alpha
chr1_+_223101757 0.44 ENST00000284476.6
DISP1
dispatched homolog 1 (Drosophila)
chr10_-_24770632 0.44 ENST00000596413.1
AL353583.1
AL353583.1
chr13_+_33160553 0.44 ENST00000315596.10
PDS5B
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr19_+_46806856 0.44 ENST00000300862.3
HIF3A
hypoxia inducible factor 3, alpha subunit
chr12_+_65004292 0.43 ENST00000542104.1
ENST00000336061.2
RASSF3
Ras association (RalGDS/AF-6) domain family member 3
chr7_+_143079000 0.42 ENST00000392910.2
ZYX
zyxin
chr11_-_64764435 0.42 ENST00000534177.1
ENST00000301887.4
BATF2
basic leucine zipper transcription factor, ATF-like 2
chr1_+_74663896 0.41 ENST00000370898.3
ENST00000467578.2
ENST00000370894.5
ENST00000482102.2
ENST00000609362.1
ENST00000534056.1
ENST00000557284.2
ENST00000370899.3
ENST00000370895.1
ENST00000534632.1
ENST00000370893.1
ENST00000370891.2
FPGT
FPGT-TNNI3K
TNNI3K
fucose-1-phosphate guanylyltransferase
FPGT-TNNI3K readthrough
TNNI3 interacting kinase
chr17_-_2996290 0.40 ENST00000331459.1
OR1D2
olfactory receptor, family 1, subfamily D, member 2
chr5_-_59783882 0.39 ENST00000505507.2
ENST00000502484.2
PDE4D
phosphodiesterase 4D, cAMP-specific
chr11_-_124180733 0.39 ENST00000357821.2
OR8D1
olfactory receptor, family 8, subfamily D, member 1
chr3_+_183948161 0.38 ENST00000426955.2
VWA5B2
von Willebrand factor A domain containing 5B2
chr2_-_241759622 0.37 ENST00000320389.7
ENST00000498729.2
KIF1A
kinesin family member 1A
chr4_-_174451370 0.36 ENST00000359562.4
HAND2
heart and neural crest derivatives expressed 2
chr2_+_128180842 0.36 ENST00000402125.2
PROC
protein C (inactivator of coagulation factors Va and VIIIa)
chr17_+_40925454 0.35 ENST00000253794.2
ENST00000590339.1
ENST00000589520.1
VPS25
vacuolar protein sorting 25 homolog (S. cerevisiae)
chr15_-_65407524 0.35 ENST00000559089.1
UBAP1L
ubiquitin associated protein 1-like
chr17_+_7341586 0.35 ENST00000575235.1
FGF11
fibroblast growth factor 11
chr4_+_114214125 0.34 ENST00000509550.1
ANK2
ankyrin 2, neuronal
chr8_-_49833978 0.34 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr12_+_6833237 0.34 ENST00000229251.3
ENST00000539735.1
ENST00000538410.1
COPS7A
COP9 signalosome subunit 7A
chrX_+_154611749 0.34 ENST00000369505.3
F8A2
coagulation factor VIII-associated 2
chr16_+_618837 0.34 ENST00000409439.2
PIGQ
phosphatidylinositol glycan anchor biosynthesis, class Q
chr17_+_74722912 0.34 ENST00000589977.1
ENST00000591571.1
ENST00000592849.1
ENST00000586738.1
ENST00000588783.1
ENST00000588563.1
ENST00000586752.1
ENST00000588302.1
ENST00000590964.1
ENST00000341249.6
ENST00000588822.1
METTL23
methyltransferase like 23
chr20_-_31124186 0.34 ENST00000375678.3
C20orf112
chromosome 20 open reading frame 112
chr6_+_159290917 0.33 ENST00000367072.1
C6orf99
chromosome 6 open reading frame 99
chr12_+_6833437 0.33 ENST00000534947.1
ENST00000541866.1
ENST00000534877.1
ENST00000538753.1
COPS7A
COP9 signalosome subunit 7A
chr6_-_119031228 0.32 ENST00000392500.3
ENST00000368488.5
ENST00000434604.1
CEP85L
centrosomal protein 85kDa-like
chr8_-_49834299 0.32 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr22_-_21905120 0.32 ENST00000331505.5
RIMBP3C
RIMS binding protein 3C
chr15_-_75660919 0.32 ENST00000569482.1
ENST00000565683.1
ENST00000561615.1
ENST00000563622.1
ENST00000568374.1
ENST00000566256.1
ENST00000267978.5
MAN2C1
mannosidase, alpha, class 2C, member 1
chr2_+_69002052 0.32 ENST00000497079.1
ARHGAP25
Rho GTPase activating protein 25
chr10_-_14050522 0.31 ENST00000342409.2
FRMD4A
FERM domain containing 4A
chr1_+_15480197 0.31 ENST00000400796.3
ENST00000434578.2
ENST00000376008.2
TMEM51
transmembrane protein 51
chr8_-_20040638 0.31 ENST00000519026.1
ENST00000276373.5
ENST00000440926.1
ENST00000437980.1
SLC18A1
solute carrier family 18 (vesicular monoamine transporter), member 1
chr2_-_152146385 0.30 ENST00000414946.1
ENST00000243346.5
NMI
N-myc (and STAT) interactor
chr20_+_58179582 0.30 ENST00000371015.1
ENST00000395639.4
PHACTR3
phosphatase and actin regulator 3
chr6_+_136172820 0.30 ENST00000308191.6
PDE7B
phosphodiesterase 7B
chr11_+_1718425 0.30 ENST00000382160.1
KRTAP5-6
keratin associated protein 5-6
chrX_-_77914825 0.30 ENST00000321110.1
ZCCHC5
zinc finger, CCHC domain containing 5
chr3_-_195310802 0.30 ENST00000421243.1
ENST00000453131.1
APOD
apolipoprotein D
chr10_-_15413035 0.30 ENST00000378116.4
ENST00000455654.1
FAM171A1
family with sequence similarity 171, member A1
chr11_+_71640112 0.29 ENST00000530137.1
RNF121
ring finger protein 121
chr3_+_42897512 0.29 ENST00000493193.1
ACKR2
atypical chemokine receptor 2
chr15_-_42749711 0.29 ENST00000565611.1
ENST00000263805.4
ENST00000565948.1
ZNF106
zinc finger protein 106
chr10_-_64576105 0.29 ENST00000242480.3
ENST00000411732.1
EGR2
early growth response 2
chr9_-_127269661 0.29 ENST00000373588.4
NR5A1
nuclear receptor subfamily 5, group A, member 1
chr1_+_110163202 0.29 ENST00000531203.1
ENST00000256578.3
AMPD2
adenosine monophosphate deaminase 2
chr11_+_71640071 0.29 ENST00000533380.1
ENST00000393713.3
ENST00000545854.1
RNF121
ring finger protein 121
chr19_+_36249044 0.29 ENST00000444637.2
ENST00000396908.4
ENST00000544099.1
C19orf55
chromosome 19 open reading frame 55
chr1_-_38273840 0.28 ENST00000373044.2
YRDC
yrdC N(6)-threonylcarbamoyltransferase domain containing
chr2_-_183903133 0.28 ENST00000361354.4
NCKAP1
NCK-associated protein 1
chr2_-_166930131 0.28 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
SCN1A
sodium channel, voltage-gated, type I, alpha subunit
chrX_+_152082969 0.28 ENST00000535861.1
ENST00000539731.1
ENST00000449285.2
ENST00000318504.7
ENST00000324823.6
ENST00000370268.4
ENST00000370270.2
ZNF185
zinc finger protein 185 (LIM domain)
chr5_+_49962772 0.28 ENST00000281631.5
ENST00000513738.1
ENST00000503665.1
ENST00000514067.2
ENST00000503046.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr2_-_152830441 0.28 ENST00000534999.1
ENST00000397327.2
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr11_+_117103441 0.28 ENST00000531287.1
ENST00000531452.1
RNF214
ring finger protein 214
chr1_+_110162448 0.27 ENST00000342115.4
ENST00000469039.2
ENST00000474459.1
ENST00000528667.1
AMPD2
adenosine monophosphate deaminase 2
chr8_-_20040601 0.27 ENST00000265808.7
ENST00000522513.1
SLC18A1
solute carrier family 18 (vesicular monoamine transporter), member 1
chr11_-_72070206 0.27 ENST00000544382.1
CLPB
ClpB caseinolytic peptidase B homolog (E. coli)
chr6_-_24911195 0.26 ENST00000259698.4
FAM65B
family with sequence similarity 65, member B
chr12_-_52715179 0.26 ENST00000293670.3
KRT83
keratin 83
chr19_+_15904761 0.26 ENST00000308940.8
OR10H5
olfactory receptor, family 10, subfamily H, member 5
chr10_-_61513146 0.26 ENST00000430431.1
LINC00948
long intergenic non-protein coding RNA 948
chr17_-_39254391 0.26 ENST00000333822.4
KRTAP4-8
keratin associated protein 4-8
chr22_-_42342692 0.26 ENST00000404067.1
ENST00000402338.1
CENPM
centromere protein M
chr7_+_73442457 0.26 ENST00000438880.1
ENST00000414324.1
ENST00000380562.4
ELN
elastin
chr4_+_113970772 0.26 ENST00000504454.1
ENST00000394537.3
ENST00000357077.4
ENST00000264366.6
ANK2
ankyrin 2, neuronal
chr17_+_74723031 0.26 ENST00000586200.1
METTL23
methyltransferase like 23
chr10_+_102759045 0.26 ENST00000370220.1
LZTS2
leucine zipper, putative tumor suppressor 2
chr17_-_3595181 0.26 ENST00000552050.1
P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chr12_+_57916466 0.26 ENST00000355673.3
MBD6
methyl-CpG binding domain protein 6
chr11_-_88796803 0.26 ENST00000418177.2
ENST00000455756.2
GRM5
glutamate receptor, metabotropic 5
chr17_-_39280419 0.25 ENST00000394014.1
KRTAP4-12
keratin associated protein 4-12
chr2_-_152830479 0.25 ENST00000360283.6
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr2_+_233562015 0.25 ENST00000427233.1
ENST00000373566.3
ENST00000373563.4
ENST00000428883.1
ENST00000456491.1
ENST00000409480.1
ENST00000421433.1
ENST00000425040.1
ENST00000430720.1
ENST00000409547.1
ENST00000423659.1
ENST00000409196.3
ENST00000409451.3
ENST00000429187.1
ENST00000440945.1
GIGYF2
GRB10 interacting GYF protein 2
chr5_-_58571935 0.24 ENST00000503258.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr20_-_56284816 0.24 ENST00000395819.3
ENST00000341744.3
PMEPA1
prostate transmembrane protein, androgen induced 1
chr7_-_150777874 0.24 ENST00000540185.1
FASTK
Fas-activated serine/threonine kinase
chr8_-_8243968 0.24 ENST00000520004.1
SGK223
Tyrosine-protein kinase SgK223
chr12_-_76478446 0.24 ENST00000393263.3
ENST00000548044.1
ENST00000547704.1
ENST00000431879.3
ENST00000549596.1
ENST00000550934.1
ENST00000551600.1
ENST00000547479.1
ENST00000547773.1
ENST00000544816.1
ENST00000542344.1
ENST00000548273.1
NAP1L1
nucleosome assembly protein 1-like 1
chr2_-_30144432 0.24 ENST00000389048.3
ALK
anaplastic lymphoma receptor tyrosine kinase
chr10_+_7745303 0.24 ENST00000429820.1
ENST00000379587.4
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr3_-_178790057 0.23 ENST00000311417.2
ZMAT3
zinc finger, matrin-type 3
chr1_+_169075554 0.23 ENST00000367815.4
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr9_+_140033862 0.23 ENST00000350902.5
ENST00000371550.4
ENST00000371546.4
ENST00000371555.4
ENST00000371553.3
ENST00000371559.4
ENST00000371560.3
GRIN1
glutamate receptor, ionotropic, N-methyl D-aspartate 1
chr6_-_42690312 0.23 ENST00000230381.5
PRPH2
peripherin 2 (retinal degeneration, slow)
chr3_-_10332416 0.23 ENST00000450603.1
ENST00000449554.2
GHRL
ghrelin/obestatin prepropeptide
chr17_+_33474826 0.23 ENST00000268876.5
ENST00000433649.1
ENST00000378449.1
UNC45B
unc-45 homolog B (C. elegans)
chr19_-_3772209 0.22 ENST00000555978.1
ENST00000555633.1
RAX2
retina and anterior neural fold homeobox 2
chr8_+_124084899 0.22 ENST00000287380.1
ENST00000309336.3
ENST00000519418.1
ENST00000327098.5
ENST00000522420.1
ENST00000521676.1
ENST00000378080.2
TBC1D31
TBC1 domain family, member 31
chr3_+_148508845 0.22 ENST00000491148.1
CPB1
carboxypeptidase B1 (tissue)
chr17_+_33474860 0.22 ENST00000394570.2
UNC45B
unc-45 homolog B (C. elegans)
chr7_-_31380502 0.22 ENST00000297142.3
NEUROD6
neuronal differentiation 6
chr8_-_10512569 0.22 ENST00000382483.3
RP1L1
retinitis pigmentosa 1-like 1
chr7_-_150777949 0.22 ENST00000482571.1
FASTK
Fas-activated serine/threonine kinase
chr1_-_40367668 0.22 ENST00000397332.2
ENST00000429311.1
MYCL
v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
chr22_-_37823468 0.21 ENST00000402918.2
ELFN2
extracellular leucine-rich repeat and fibronectin type III domain containing 2
chr2_+_137523086 0.21 ENST00000409968.1
THSD7B
thrombospondin, type I, domain containing 7B
chr17_-_4890649 0.21 ENST00000361571.5
CAMTA2
calmodulin binding transcription activator 2
chr4_-_69215699 0.21 ENST00000510746.1
ENST00000344157.4
ENST00000355665.3
YTHDC1
YTH domain containing 1
chr16_+_30383613 0.21 ENST00000568749.1
MYLPF
myosin light chain, phosphorylatable, fast skeletal muscle
chr3_-_39234074 0.21 ENST00000340369.3
ENST00000421646.1
ENST00000396251.1
XIRP1
xin actin-binding repeat containing 1
chr11_-_14913190 0.21 ENST00000532378.1
CYP2R1
cytochrome P450, family 2, subfamily R, polypeptide 1
chr11_+_71498552 0.21 ENST00000346333.6
ENST00000359244.4
ENST00000426628.2
FAM86C1
family with sequence similarity 86, member C1
chr15_-_63448973 0.21 ENST00000462430.1
RPS27L
ribosomal protein S27-like
chr12_+_53491220 0.21 ENST00000548547.1
ENST00000301464.3
IGFBP6
insulin-like growth factor binding protein 6
chr11_+_67222818 0.21 ENST00000325656.5
CABP4
calcium binding protein 4
chr7_+_18535346 0.20 ENST00000405010.3
ENST00000406451.4
ENST00000428307.2
HDAC9
histone deacetylase 9
chr18_+_47088401 0.20 ENST00000261292.4
ENST00000427224.2
ENST00000580036.1
LIPG
lipase, endothelial
chrX_+_30671476 0.20 ENST00000378946.3
ENST00000378943.3
ENST00000378945.3
ENST00000427190.1
ENST00000378941.3
GK
glycerol kinase
chr5_+_173472607 0.20 ENST00000303177.3
ENST00000519867.1
NSG2
Neuron-specific protein family member 2
chr3_+_42727011 0.20 ENST00000287777.4
KLHL40
kelch-like family member 40
chr1_-_236046872 0.20 ENST00000536965.1
LYST
lysosomal trafficking regulator
chr19_-_6720686 0.20 ENST00000245907.6
C3
complement component 3
chr15_-_28419569 0.20 ENST00000569772.1
HERC2
HECT and RLD domain containing E3 ubiquitin protein ligase 2
chr3_+_46919235 0.20 ENST00000449590.1
PTH1R
parathyroid hormone 1 receptor
chr7_-_150777920 0.20 ENST00000353841.2
ENST00000297532.6
FASTK
Fas-activated serine/threonine kinase
chr8_+_92082424 0.20 ENST00000285420.4
ENST00000404789.3
OTUD6B
OTU domain containing 6B
chr8_+_9413410 0.19 ENST00000520408.1
ENST00000310430.6
ENST00000522110.1
TNKS
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr1_+_1567546 0.19 ENST00000378675.3
MMP23B
matrix metallopeptidase 23B
chr12_-_7245125 0.19 ENST00000542285.1
ENST00000540610.1
C1R
complement component 1, r subcomponent
chr19_-_47164386 0.19 ENST00000391916.2
ENST00000410105.2
DACT3
dishevelled-binding antagonist of beta-catenin 3
chr22_-_50964558 0.19 ENST00000535425.1
ENST00000439934.1
SCO2
SCO2 cytochrome c oxidase assembly protein
chr10_-_73848531 0.19 ENST00000373109.2
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr14_+_90422239 0.19 ENST00000393452.3
ENST00000554180.1
ENST00000393454.2
ENST00000553617.1
ENST00000335725.4
ENST00000357382.3
ENST00000556867.1
ENST00000553527.1
TDP1
tyrosyl-DNA phosphodiesterase 1
chr17_-_47841485 0.19 ENST00000506156.1
ENST00000240364.2
FAM117A
family with sequence similarity 117, member A
chr2_-_2334888 0.19 ENST00000428368.2
ENST00000399161.2
MYT1L
myelin transcription factor 1-like
chr17_+_41132564 0.19 ENST00000361677.1
ENST00000589705.1
RUNDC1
RUN domain containing 1
chr10_-_103347883 0.19 ENST00000339310.3
ENST00000370158.3
ENST00000299206.4
ENST00000456836.2
ENST00000413344.1
ENST00000429502.1
ENST00000430045.1
ENST00000370172.1
ENST00000436284.2
ENST00000370162.3
POLL
polymerase (DNA directed), lambda
chr6_-_26250835 0.18 ENST00000446824.2
HIST1H3F
histone cluster 1, H3f
chr4_-_20985632 0.18 ENST00000359001.5
KCNIP4
Kv channel interacting protein 4
chr11_-_71639670 0.18 ENST00000533047.1
ENST00000529844.1
RP11-849H4.2
Putative short transient receptor potential channel 2-like protein
chr1_+_222885884 0.18 ENST00000340934.5
BROX
BRO1 domain and CAAX motif containing
chr10_+_1102303 0.18 ENST00000381329.1
WDR37
WD repeat domain 37
chr11_-_1643368 0.18 ENST00000399682.1
KRTAP5-4
keratin associated protein 5-4
chr1_-_33647267 0.18 ENST00000291416.5
TRIM62
tripartite motif containing 62
chr1_+_12524965 0.18 ENST00000471923.1
VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr2_-_220264703 0.18 ENST00000519905.1
ENST00000523282.1
ENST00000434339.1
ENST00000457935.1
DNPEP
aspartyl aminopeptidase
chr21_+_38593701 0.18 ENST00000440629.1
AP001432.14
AP001432.14
chrX_-_32173579 0.17 ENST00000359836.1
ENST00000343523.2
ENST00000378707.3
ENST00000541735.1
ENST00000474231.1
DMD
dystrophin
chr12_-_76478686 0.17 ENST00000261182.8
NAP1L1
nucleosome assembly protein 1-like 1
chr11_+_117073850 0.17 ENST00000529622.1
TAGLN
transgelin
chrX_+_69509927 0.17 ENST00000374403.3
KIF4A
kinesin family member 4A
chr5_-_36241900 0.17 ENST00000381937.4
ENST00000514504.1
NADK2
NAD kinase 2, mitochondrial
chr22_-_31885514 0.17 ENST00000397525.1
EIF4ENIF1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr1_-_111174054 0.17 ENST00000369770.3
KCNA2
potassium voltage-gated channel, shaker-related subfamily, member 2
chr9_+_133710453 0.17 ENST00000318560.5
ABL1
c-abl oncogene 1, non-receptor tyrosine kinase

Network of associatons between targets according to the STRING database.

First level regulatory network of OLIG2_NEUROD1_ATOH1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.5 1.4 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.5 3.7 GO:0018377 protein myristoylation(GO:0018377)
0.4 2.7 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.3 0.8 GO:2000296 cadmium ion homeostasis(GO:0055073) lysosomal membrane organization(GO:0097212) negative regulation of hydrogen peroxide catabolic process(GO:2000296) regulation of oxygen metabolic process(GO:2000374)
0.3 0.8 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.2 1.0 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.2 0.7 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.2 0.6 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.2 0.6 GO:0036371 protein localization to T-tubule(GO:0036371)
0.2 0.8 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
0.2 0.6 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.2 0.7 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.2 0.9 GO:2001293 fatty-acyl-CoA catabolic process(GO:0036115) malonyl-CoA metabolic process(GO:2001293)
0.2 1.5 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.2 0.5 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.2 0.6 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.1 1.6 GO:0009414 response to water deprivation(GO:0009414)
0.1 0.6 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.1 0.4 GO:0097325 melanocyte proliferation(GO:0097325)
0.1 0.3 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.3 GO:0035283 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 0.3 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.7 GO:0021564 vagus nerve development(GO:0021564)
0.1 0.3 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 2.0 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.1 0.2 GO:0008355 olfactory learning(GO:0008355) cellular alkene metabolic process(GO:0043449)
0.1 0.2 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.1 0.2 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.1 0.2 GO:1904344 positive regulation of growth rate(GO:0040010) regulation of gastric mucosal blood circulation(GO:1904344) positive regulation of gastric mucosal blood circulation(GO:1904346) gastric mucosal blood circulation(GO:1990768)
0.1 0.2 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
0.1 0.4 GO:0003219 cardiac right ventricle formation(GO:0003219) visceral serous pericardium development(GO:0061032)
0.1 0.3 GO:0007538 primary sex determination(GO:0007538) negative regulation of female gonad development(GO:2000195)
0.1 0.4 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.1 0.2 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1 0.3 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.1 0.2 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.1 0.2 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 0.2 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.1 0.3 GO:0072277 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.1 0.6 GO:0032264 IMP salvage(GO:0032264)
0.1 0.2 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.1 0.2 GO:0036269 swimming behavior(GO:0036269)
0.1 0.2 GO:0001922 B-1 B cell homeostasis(GO:0001922)
0.1 0.3 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 0.2 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.0 0.1 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.0 0.2 GO:0070213 negative regulation of sister chromatid cohesion(GO:0045875) protein auto-ADP-ribosylation(GO:0070213)
0.0 0.1 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.0 0.2 GO:1903288 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281) positive regulation of potassium ion import(GO:1903288)
0.0 0.1 GO:0034970 histone H3-R2 methylation(GO:0034970)
0.0 0.1 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.2 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.0 0.7 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.3 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.2 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.0 0.1 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.0 0.2 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.1 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0 0.5 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.1 GO:0003064 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.0 0.1 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0 0.1 GO:0046521 sphingoid catabolic process(GO:0046521)
0.0 0.1 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.0 0.4 GO:0060539 diaphragm development(GO:0060539)
0.0 0.2 GO:0021633 optic nerve structural organization(GO:0021633)
0.0 0.1 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877) negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.0 0.5 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.1 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.0 0.3 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.2 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.2 GO:0045631 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 1.2 GO:0001782 B cell homeostasis(GO:0001782)
0.0 0.1 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.2 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.0 0.3 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.1 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.0 0.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 0.5 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.1 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.1 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.0 0.1 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0 0.0 GO:2000705 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.0 0.2 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.0 0.1 GO:0019230 proprioception(GO:0019230)
0.0 0.2 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.5 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.5 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.1 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.1 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.0 0.5 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.2 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.5 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808) L-cystine transport(GO:0015811)
0.0 0.7 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.0 0.2 GO:0021678 third ventricle development(GO:0021678)
0.0 0.4 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.1 GO:1902613 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.0 0.4 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.6 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.1 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.0 0.4 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.2 GO:0000012 single strand break repair(GO:0000012)
0.0 0.0 GO:0034136 negative regulation of toll-like receptor 2 signaling pathway(GO:0034136)
0.0 0.2 GO:0090050 peptidyl-lysine deacetylation(GO:0034983) positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.1 GO:0046836 glycolipid transport(GO:0046836)
0.0 0.1 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.2 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.0 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.0 0.0 GO:1901594 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.0 0.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.0 0.3 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 1.0 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0 0.1 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.1 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.1 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.1 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
0.0 0.6 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.1 GO:0009624 response to nematode(GO:0009624)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.1 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.1 GO:0071313 cellular response to caffeine(GO:0071313)
0.0 0.1 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.7 GO:0000060 protein import into nucleus, translocation(GO:0000060)
0.0 0.2 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.0 GO:0001562 response to protozoan(GO:0001562)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.3 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.0 GO:0035509 negative regulation of myosin-light-chain-phosphatase activity(GO:0035509) negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.1 GO:0060437 lung growth(GO:0060437)
0.0 0.2 GO:0045176 apical protein localization(GO:0045176)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.3 0.8 GO:0097450 astrocyte end-foot(GO:0097450)
0.1 0.6 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 0.4 GO:0000814 ESCRT II complex(GO:0000814)
0.1 0.6 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 0.6 GO:1990393 3M complex(GO:1990393)
0.1 2.5 GO:0033268 node of Ranvier(GO:0033268)
0.1 0.2 GO:0060199 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.1 0.6 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.1 0.6 GO:0071953 elastic fiber(GO:0071953)
0.0 1.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.2 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.1 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.4 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 2.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.7 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 2.7 GO:0005811 lipid particle(GO:0005811)
0.0 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.4 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.1 GO:1990745 EARP complex(GO:1990745)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.2 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.2 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.9 GO:0043034 costamere(GO:0043034)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.5 GO:0097440 apical dendrite(GO:0097440)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.6 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0000125 PCAF complex(GO:0000125)
0.0 0.8 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.2 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.7 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.0 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.0 GO:1990032 parallel fiber(GO:1990032)
0.0 0.3 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.2 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.4 GO:0009041 uridylate kinase activity(GO:0009041)
0.5 1.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.3 3.7 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.3 0.8 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.2 0.7 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.2 0.8 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.2 0.6 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.2 0.6 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.1 0.3 GO:0008859 exoribonuclease II activity(GO:0008859)
0.1 0.6 GO:0070568 guanylyltransferase activity(GO:0070568)
0.1 1.5 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 0.2 GO:0031768 ghrelin receptor binding(GO:0031768)
0.1 0.6 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.9 GO:0046870 cadmium ion binding(GO:0046870)
0.1 0.2 GO:0004370 glycerol kinase activity(GO:0004370)
0.1 0.3 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 0.6 GO:0031013 troponin I binding(GO:0031013)
0.1 0.9 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.3 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.1 0.7 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.2 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.0 0.2 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.5 GO:0098960 postsynaptic neurotransmitter receptor activity(GO:0098960)
0.0 0.1 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.4 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.4 GO:0015197 peptide transporter activity(GO:0015197)
0.0 0.1 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.0 0.4 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.3 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.3 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.2 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.2 GO:0004515 nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.3 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.1 GO:0015184 L-alanine transmembrane transporter activity(GO:0015180) L-cystine transmembrane transporter activity(GO:0015184) alanine transmembrane transporter activity(GO:0022858)
0.0 0.4 GO:0005549 odorant binding(GO:0005549)
0.0 1.6 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 1.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.3 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.0 0.1 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.2 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.1 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 0.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.3 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.0 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.7 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 5.1 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.2 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.0 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 0.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 2.0 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.4 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.4 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.9 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.1 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.1 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.8 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 4.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.8 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.5 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.3 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.3 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 1.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.8 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.3 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.2 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 3.7 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.7 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.1 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions