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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for OLIG3_NEUROD2_NEUROG2

Z-value: 0.65

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Transcription factors associated with OLIG3_NEUROD2_NEUROG2

Gene Symbol Gene ID Gene Info
OLIG3
ENSG00000177468.5 oligodendrocyte transcription factor 3
NEUROD2
ENSG00000171532.4 neuronal differentiation 2
NEUROG2
ENSG00000178403.3 neurogenin 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NEUROG2hg19_v2_chr4_-_113437328_113437337-0.213.1e-01Click!
OLIG3hg19_v2_chr6_-_137815524_137815537-0.193.5e-01Click!
NEUROD2hg19_v2_chr17_-_37764128_37764258-0.135.4e-01Click!

Activity profile of OLIG3_NEUROD2_NEUROG2 motif

Sorted Z-values of OLIG3_NEUROD2_NEUROG2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_144354644 2.10 ENST00000512843.1
GAB1
GRB2-associated binding protein 1
chr5_-_111312622 1.69 ENST00000395634.3
NREP
neuronal regeneration related protein
chr3_-_18480260 1.61 ENST00000454909.2
SATB1
SATB homeobox 1
chr1_+_47489240 1.58 ENST00000371901.3
CYP4X1
cytochrome P450, family 4, subfamily X, polypeptide 1
chr8_-_93029865 1.39 ENST00000422361.2
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr3_-_108672742 1.18 ENST00000261047.3
GUCA1C
guanylate cyclase activator 1C
chr2_+_108994466 1.14 ENST00000272452.2
SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
chr17_-_58469591 1.11 ENST00000589335.1
USP32
ubiquitin specific peptidase 32
chr7_-_11871815 1.00 ENST00000423059.4
THSD7A
thrombospondin, type I, domain containing 7A
chr2_+_108994633 0.98 ENST00000409309.3
SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
chr3_-_108672609 0.98 ENST00000393963.3
ENST00000471108.1
GUCA1C
guanylate cyclase activator 1C
chr19_-_11450249 0.98 ENST00000222120.3
RAB3D
RAB3D, member RAS oncogene family
chr13_+_49551020 0.97 ENST00000541916.1
FNDC3A
fibronectin type III domain containing 3A
chr1_-_186344802 0.93 ENST00000451586.1
TPR
translocated promoter region, nuclear basket protein
chr14_-_107283278 0.87 ENST00000390639.2
IGHV7-81
immunoglobulin heavy variable 7-81 (non-functional)
chr4_+_156587979 0.72 ENST00000511507.1
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr2_-_188378368 0.71 ENST00000392365.1
ENST00000435414.1
TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr15_-_98417780 0.69 ENST00000503874.3
LINC00923
long intergenic non-protein coding RNA 923
chr17_+_66511540 0.68 ENST00000588188.2
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr4_+_156587853 0.68 ENST00000506455.1
ENST00000511108.1
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr4_-_159094194 0.57 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
FAM198B
family with sequence similarity 198, member B
chr10_+_5135981 0.56 ENST00000380554.3
AKR1C3
aldo-keto reductase family 1, member C3
chr3_+_49840685 0.54 ENST00000333323.4
FAM212A
family with sequence similarity 212, member A
chr10_-_7513904 0.52 ENST00000420395.1
RP5-1031D4.2
RP5-1031D4.2
chr6_+_3000057 0.52 ENST00000397717.2
NQO2
NAD(P)H dehydrogenase, quinone 2
chr9_+_12775011 0.48 ENST00000319264.3
LURAP1L
leucine rich adaptor protein 1-like
chr12_+_26126681 0.47 ENST00000542865.1
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr8_+_21915368 0.47 ENST00000265800.5
ENST00000517418.1
DMTN
dematin actin binding protein
chr2_-_166930131 0.46 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
SCN1A
sodium channel, voltage-gated, type I, alpha subunit
chr9_+_72002837 0.45 ENST00000377216.3
FAM189A2
family with sequence similarity 189, member A2
chr5_+_140571902 0.44 ENST00000239446.4
PCDHB10
protocadherin beta 10
chr17_+_73629500 0.44 ENST00000375215.3
SMIM5
small integral membrane protein 5
chr2_+_177053307 0.44 ENST00000331462.4
HOXD1
homeobox D1
chr1_+_180897269 0.43 ENST00000367587.1
KIAA1614
KIAA1614
chr7_+_141478242 0.41 ENST00000247881.2
TAS2R4
taste receptor, type 2, member 4
chr7_+_116502605 0.41 ENST00000458284.2
ENST00000490693.1
CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr11_-_72070206 0.41 ENST00000544382.1
CLPB
ClpB caseinolytic peptidase B homolog (E. coli)
chr1_+_244214577 0.41 ENST00000358704.4
ZBTB18
zinc finger and BTB domain containing 18
chr7_-_112758589 0.41 ENST00000413744.1
ENST00000439551.1
ENST00000441359.1
LINC00998
long intergenic non-protein coding RNA 998
chr15_+_65843130 0.40 ENST00000569894.1
PTPLAD1
protein tyrosine phosphatase-like A domain containing 1
chr11_-_110167352 0.39 ENST00000533991.1
ENST00000528498.1
ENST00000405097.1
ENST00000528900.1
ENST00000530301.1
ENST00000343115.4
RDX
radixin
chrX_+_118108601 0.39 ENST00000371628.3
LONRF3
LON peptidase N-terminal domain and ring finger 3
chr19_-_52227221 0.39 ENST00000222115.1
ENST00000540069.2
HAS1
hyaluronan synthase 1
chr2_-_183106641 0.38 ENST00000346717.4
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chrX_+_118108571 0.38 ENST00000304778.7
LONRF3
LON peptidase N-terminal domain and ring finger 3
chr3_-_197300194 0.37 ENST00000358186.2
ENST00000431056.1
BDH1
3-hydroxybutyrate dehydrogenase, type 1
chr20_+_34802295 0.37 ENST00000432603.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr2_-_183387430 0.37 ENST00000410103.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr3_-_178984759 0.36 ENST00000349697.2
ENST00000497599.1
KCNMB3
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr14_-_69864993 0.36 ENST00000555373.1
ERH
enhancer of rudimentary homolog (Drosophila)
chr4_-_100575781 0.36 ENST00000511828.1
RP11-766F14.2
Protein LOC285556
chr14_+_63671577 0.35 ENST00000555125.1
RHOJ
ras homolog family member J
chr2_-_165424973 0.35 ENST00000543549.1
GRB14
growth factor receptor-bound protein 14
chr9_-_75567962 0.35 ENST00000297785.3
ENST00000376939.1
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chrX_-_125686784 0.35 ENST00000371126.1
DCAF12L1
DDB1 and CUL4 associated factor 12-like 1
chr12_+_56862301 0.35 ENST00000338146.5
SPRYD4
SPRY domain containing 4
chr6_-_52859046 0.34 ENST00000457564.1
ENST00000541324.1
ENST00000370960.1
GSTA4
glutathione S-transferase alpha 4
chr7_-_101212244 0.34 ENST00000451953.1
ENST00000434537.1
ENST00000437900.1
LINC01007
long intergenic non-protein coding RNA 1007
chr8_+_7801144 0.33 ENST00000443676.1
ZNF705B
zinc finger protein 705B
chr17_+_56769924 0.33 ENST00000461271.1
ENST00000583539.1
ENST00000337432.4
ENST00000421782.2
RAD51C
RAD51 paralog C
chr1_-_21377383 0.33 ENST00000374935.3
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr6_-_76072719 0.32 ENST00000370020.1
FILIP1
filamin A interacting protein 1
chr7_-_156685841 0.32 ENST00000354505.4
ENST00000540390.1
LMBR1
limb development membrane protein 1
chr6_-_29324054 0.32 ENST00000543825.1
OR5V1
olfactory receptor, family 5, subfamily V, member 1
chr11_+_7506713 0.32 ENST00000329293.3
ENST00000534244.1
OLFML1
olfactomedin-like 1
chr3_-_195310802 0.31 ENST00000421243.1
ENST00000453131.1
APOD
apolipoprotein D
chr3_+_141043050 0.31 ENST00000509842.1
ZBTB38
zinc finger and BTB domain containing 38
chr7_+_114562909 0.31 ENST00000423503.1
ENST00000427207.1
MDFIC
MyoD family inhibitor domain containing
chr7_+_142031986 0.30 ENST00000547918.2
TRBV7-1
T cell receptor beta variable 7-1 (non-functional)
chr16_+_81272287 0.30 ENST00000425577.2
ENST00000564552.1
BCMO1
beta-carotene 15,15'-monooxygenase 1
chr2_+_54342574 0.30 ENST00000303536.4
ENST00000394666.3
ACYP2
acylphosphatase 2, muscle type
chr15_-_71055878 0.29 ENST00000322954.6
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr17_+_60758814 0.29 ENST00000579432.1
ENST00000446119.2
MRC2
mannose receptor, C type 2
chr9_+_5450503 0.29 ENST00000381573.4
ENST00000381577.3
CD274
CD274 molecule
chr17_+_7211656 0.29 ENST00000416016.2
EIF5A
eukaryotic translation initiation factor 5A
chr3_+_119298429 0.28 ENST00000478927.1
ADPRH
ADP-ribosylarginine hydrolase
chr9_+_2029019 0.28 ENST00000382194.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr2_-_183387064 0.28 ENST00000536095.1
ENST00000331935.6
ENST00000358139.2
ENST00000456212.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr6_+_3000195 0.28 ENST00000338130.2
NQO2
NAD(P)H dehydrogenase, quinone 2
chr11_-_11374904 0.28 ENST00000528848.2
CSNK2A3
casein kinase 2, alpha 3 polypeptide
chr2_+_191792376 0.28 ENST00000409428.1
ENST00000409215.1
GLS
glutaminase
chr11_+_92085707 0.28 ENST00000525166.1
FAT3
FAT atypical cadherin 3
chr14_+_22675388 0.27 ENST00000390461.2
TRAV34
T cell receptor alpha variable 34
chr11_+_120107344 0.27 ENST00000260264.4
POU2F3
POU class 2 homeobox 3
chr16_-_72206034 0.27 ENST00000537465.1
ENST00000237353.10
PMFBP1
polyamine modulated factor 1 binding protein 1
chr7_+_134430212 0.27 ENST00000436461.2
CALD1
caldesmon 1
chr4_-_116034979 0.27 ENST00000264363.2
NDST4
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
chr12_-_91573132 0.26 ENST00000550563.1
ENST00000546370.1
DCN
decorin
chr4_-_186733363 0.26 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
SORBS2
sorbin and SH3 domain containing 2
chr9_-_111775772 0.26 ENST00000325580.6
ENST00000374593.4
ENST00000374595.4
ENST00000325551.4
CTNNAL1
catenin (cadherin-associated protein), alpha-like 1
chr1_+_100810575 0.25 ENST00000542213.1
CDC14A
cell division cycle 14A
chr5_-_171433579 0.25 ENST00000265094.5
ENST00000393802.2
FBXW11
F-box and WD repeat domain containing 11
chr6_+_3000218 0.25 ENST00000380441.1
ENST00000380455.4
ENST00000380454.4
NQO2
NAD(P)H dehydrogenase, quinone 2
chr12_-_108954933 0.25 ENST00000431469.2
ENST00000546815.1
SART3
squamous cell carcinoma antigen recognized by T cells 3
chr10_+_133918175 0.25 ENST00000298622.4
JAKMIP3
Janus kinase and microtubule interacting protein 3
chr9_-_125675576 0.25 ENST00000373659.3
ZBTB6
zinc finger and BTB domain containing 6
chr15_-_80189380 0.25 ENST00000258874.3
MTHFS
5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
chr20_-_34117447 0.25 ENST00000246199.2
ENST00000424444.1
ENST00000374345.4
ENST00000444723.1
C20orf173
chromosome 20 open reading frame 173
chr11_-_134123142 0.25 ENST00000392595.2
ENST00000341541.3
ENST00000352327.5
ENST00000392594.3
THYN1
thymocyte nuclear protein 1
chr1_-_21377447 0.25 ENST00000374937.3
ENST00000264211.8
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr5_-_11588907 0.25 ENST00000513598.1
ENST00000503622.1
CTNND2
catenin (cadherin-associated protein), delta 2
chr14_-_38725573 0.25 ENST00000342213.2
CLEC14A
C-type lectin domain family 14, member A
chr3_-_114477962 0.25 ENST00000471418.1
ZBTB20
zinc finger and BTB domain containing 20
chr11_+_55944094 0.25 ENST00000312298.1
OR5J2
olfactory receptor, family 5, subfamily J, member 2
chr15_+_85144217 0.24 ENST00000540936.1
ENST00000448803.2
ENST00000546275.1
ENST00000546148.1
ENST00000442073.3
ENST00000334141.3
ENST00000358472.3
ENST00000502939.2
ENST00000379358.3
ENST00000327179.6
ZSCAN2
zinc finger and SCAN domain containing 2
chr2_+_33359687 0.24 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
LTBP1
latent transforming growth factor beta binding protein 1
chr19_+_18208603 0.24 ENST00000262811.6
MAST3
microtubule associated serine/threonine kinase 3
chr6_-_33714752 0.23 ENST00000451316.1
IP6K3
inositol hexakisphosphate kinase 3
chr11_+_134123389 0.23 ENST00000281182.4
ENST00000537423.1
ENST00000543332.1
ENST00000374752.4
ACAD8
acyl-CoA dehydrogenase family, member 8
chr9_+_90112117 0.23 ENST00000358077.5
DAPK1
death-associated protein kinase 1
chr11_+_118175596 0.23 ENST00000528600.1
CD3E
CD3e molecule, epsilon (CD3-TCR complex)
chr2_+_33359646 0.23 ENST00000390003.4
ENST00000418533.2
LTBP1
latent transforming growth factor beta binding protein 1
chr1_+_225600404 0.23 ENST00000366845.2
AC092811.1
AC092811.1
chr8_+_86121448 0.23 ENST00000520225.1
E2F5
E2F transcription factor 5, p130-binding
chr11_+_118175132 0.23 ENST00000361763.4
CD3E
CD3e molecule, epsilon (CD3-TCR complex)
chr6_-_30712313 0.23 ENST00000376377.2
ENST00000259874.5
IER3
immediate early response 3
chr6_-_33714667 0.23 ENST00000293756.4
IP6K3
inositol hexakisphosphate kinase 3
chr2_+_136499179 0.23 ENST00000272638.9
UBXN4
UBX domain protein 4
chr19_+_35417798 0.22 ENST00000303586.7
ENST00000439785.1
ENST00000601540.1
ZNF30
zinc finger protein 30
chr3_-_114477787 0.22 ENST00000464560.1
ZBTB20
zinc finger and BTB domain containing 20
chr12_+_54393880 0.22 ENST00000303450.4
HOXC9
homeobox C9
chr8_-_16050142 0.22 ENST00000536385.1
ENST00000381998.4
MSR1
macrophage scavenger receptor 1
chr18_+_3448455 0.22 ENST00000549780.1
TGIF1
TGFB-induced factor homeobox 1
chr10_-_48055018 0.22 ENST00000426610.2
ASAH2C
N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2C
chr20_+_57226841 0.22 ENST00000358029.4
ENST00000361830.3
STX16
syntaxin 16
chrX_+_135278908 0.22 ENST00000539015.1
ENST00000370683.1
FHL1
four and a half LIM domains 1
chr16_+_31366455 0.22 ENST00000268296.4
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr4_-_83719884 0.22 ENST00000282709.4
ENST00000273908.4
SCD5
stearoyl-CoA desaturase 5
chr2_+_173600514 0.22 ENST00000264111.6
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr8_-_16050214 0.22 ENST00000262101.5
MSR1
macrophage scavenger receptor 1
chr21_+_17566643 0.22 ENST00000419952.1
ENST00000445461.2
LINC00478
long intergenic non-protein coding RNA 478
chr4_-_147043058 0.22 ENST00000512063.1
ENST00000507726.1
RP11-6L6.3
long intergenic non-protein coding RNA 1095
chr2_-_113999260 0.21 ENST00000468980.2
PAX8
paired box 8
chr1_+_95975672 0.21 ENST00000440116.2
ENST00000456933.1
RP11-286B14.1
RP11-286B14.1
chr12_-_102872317 0.21 ENST00000424202.2
IGF1
insulin-like growth factor 1 (somatomedin C)
chr16_+_12058961 0.21 ENST00000053243.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr7_-_38403077 0.21 ENST00000426402.2
TRGV2
T cell receptor gamma variable 2
chrX_+_47444613 0.21 ENST00000445623.1
TIMP1
TIMP metallopeptidase inhibitor 1
chr14_+_24540046 0.20 ENST00000397016.2
ENST00000537691.1
ENST00000560356.1
ENST00000558450.1
CPNE6
copine VI (neuronal)
chr12_+_82347498 0.20 ENST00000550506.1
RP11-362A1.1
RP11-362A1.1
chr17_-_47925379 0.20 ENST00000352793.2
ENST00000334568.4
ENST00000398154.1
ENST00000436235.1
ENST00000326219.5
TAC4
tachykinin 4 (hemokinin)
chr16_+_12059050 0.20 ENST00000396495.3
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr15_-_65503801 0.20 ENST00000261883.4
CILP
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr20_+_10199468 0.20 ENST00000254976.2
ENST00000304886.2
SNAP25
synaptosomal-associated protein, 25kDa
chr2_+_173600565 0.20 ENST00000397081.3
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr14_+_69865401 0.20 ENST00000556605.1
ENST00000336643.5
ENST00000031146.4
SLC39A9
solute carrier family 39, member 9
chr2_+_189839046 0.20 ENST00000304636.3
ENST00000317840.5
COL3A1
collagen, type III, alpha 1
chr1_-_55352834 0.20 ENST00000371269.3
DHCR24
24-dehydrocholesterol reductase
chr15_+_75940218 0.20 ENST00000308527.5
SNX33
sorting nexin 33
chr19_+_50194360 0.20 ENST00000323446.5
ENST00000392518.4
ENST00000598396.1
ENST00000598293.1
ENST00000354199.5
ENST00000405931.2
ENST00000602019.1
CPT1C
carnitine palmitoyltransferase 1C
chr11_-_5537920 0.20 ENST00000380184.1
UBQLNL
ubiquilin-like
chr19_-_14945933 0.20 ENST00000322301.3
OR7A5
olfactory receptor, family 7, subfamily A, member 5
chr13_+_49794474 0.20 ENST00000218721.1
ENST00000398307.1
MLNR
motilin receptor
chr4_+_71458012 0.20 ENST00000449493.2
AMBN
ameloblastin (enamel matrix protein)
chr19_-_37019562 0.19 ENST00000523638.1
ZNF260
zinc finger protein 260
chr3_-_98241358 0.19 ENST00000503004.1
ENST00000506575.1
ENST00000513452.1
ENST00000515620.1
CLDND1
claudin domain containing 1
chr14_-_106539557 0.19 ENST00000390599.2
IGHV1-8
immunoglobulin heavy variable 1-8
chr8_-_135522425 0.19 ENST00000521673.1
ZFAT
zinc finger and AT hook domain containing
chr7_+_148287657 0.19 ENST00000307003.2
C7orf33
chromosome 7 open reading frame 33
chr5_+_156607829 0.19 ENST00000422843.3
ITK
IL2-inducible T-cell kinase
chr2_+_71680852 0.19 ENST00000409762.1
ENST00000409582.3
ENST00000429174.2
ENST00000413539.2
ENST00000258104.3
DYSF
dysferlin
chr4_-_22444733 0.19 ENST00000508133.1
GPR125
G protein-coupled receptor 125
chrX_+_78426469 0.19 ENST00000276077.1
GPR174
G protein-coupled receptor 174
chr16_-_21877629 0.19 ENST00000544693.1
NPIPB4
nuclear pore complex interacting protein family, member B4
chr16_+_2016821 0.19 ENST00000569210.2
ENST00000569714.1
RNF151
ring finger protein 151
chr14_+_27342334 0.19 ENST00000548170.1
ENST00000552926.1
RP11-384J4.1
RP11-384J4.1
chr16_-_66583701 0.19 ENST00000527800.1
ENST00000525974.1
ENST00000563369.2
TK2
thymidine kinase 2, mitochondrial
chr16_+_49407710 0.19 ENST00000299191.3
C16orf78
chromosome 16 open reading frame 78
chr8_-_19540086 0.18 ENST00000332246.6
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr8_-_38239732 0.18 ENST00000534155.1
ENST00000433384.2
ENST00000317025.8
ENST00000316985.3
WHSC1L1
Wolf-Hirschhorn syndrome candidate 1-like 1
chr10_-_76995769 0.18 ENST00000372538.3
COMTD1
catechol-O-methyltransferase domain containing 1
chr19_-_1021113 0.18 ENST00000333175.5
ENST00000356663.3
TMEM259
transmembrane protein 259
chr17_+_66255310 0.18 ENST00000448504.2
ARSG
arylsulfatase G
chr10_-_94257512 0.18 ENST00000371581.5
IDE
insulin-degrading enzyme
chr18_+_77623668 0.18 ENST00000316249.3
KCNG2
potassium voltage-gated channel, subfamily G, member 2
chr22_+_44319619 0.18 ENST00000216180.3
PNPLA3
patatin-like phospholipase domain containing 3
chr1_-_44818599 0.17 ENST00000537474.1
ERI3
ERI1 exoribonuclease family member 3
chr4_+_174818390 0.17 ENST00000509968.1
ENST00000512263.1
RP11-161D15.1
RP11-161D15.1
chr5_-_11589131 0.17 ENST00000511377.1
CTNND2
catenin (cadherin-associated protein), delta 2
chr10_-_48416849 0.17 ENST00000249598.1
GDF2
growth differentiation factor 2
chr17_+_63133587 0.17 ENST00000449996.3
ENST00000262406.9
RGS9
regulator of G-protein signaling 9
chr10_-_76995675 0.17 ENST00000469299.1
COMTD1
catechol-O-methyltransferase domain containing 1
chr5_+_175299743 0.17 ENST00000502265.1
CPLX2
complexin 2
chr13_+_28519343 0.17 ENST00000381026.3
ATP5EP2
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit pseudogene 2
chr15_+_74466012 0.16 ENST00000249842.3
ISLR
immunoglobulin superfamily containing leucine-rich repeat
chr16_+_53133070 0.16 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr4_+_71457970 0.16 ENST00000322937.6
AMBN
ameloblastin (enamel matrix protein)
chr5_+_135496675 0.16 ENST00000507637.1
SMAD5
SMAD family member 5
chr16_-_28550348 0.16 ENST00000324873.6
NUPR1
nuclear protein, transcriptional regulator, 1
chr5_+_147443534 0.16 ENST00000398454.1
ENST00000359874.3
ENST00000508733.1
ENST00000256084.7
SPINK5
serine peptidase inhibitor, Kazal type 5
chr8_-_17752996 0.16 ENST00000381841.2
ENST00000427924.1
FGL1
fibrinogen-like 1
chr12_-_108714412 0.16 ENST00000412676.1
ENST00000550573.1
CMKLR1
chemokine-like receptor 1
chr11_+_114310237 0.16 ENST00000539119.1
REXO2
RNA exonuclease 2
chr9_-_14180778 0.16 ENST00000380924.1
ENST00000543693.1
NFIB
nuclear factor I/B
chr4_-_150736962 0.16 ENST00000502345.1
ENST00000510975.1
ENST00000511993.1
RP11-526A4.1
RP11-526A4.1
chr2_+_179184955 0.16 ENST00000315022.2
OSBPL6
oxysterol binding protein-like 6
chr16_+_22516172 0.16 ENST00000543407.1
NPIPB5
nuclear pore complex interacting protein family, member B5
chr13_+_111767650 0.16 ENST00000449979.1
ENST00000370623.3
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr11_+_114310164 0.16 ENST00000544196.1
ENST00000539754.1
ENST00000539275.1
REXO2
RNA exonuclease 2
chr11_+_121461097 0.16 ENST00000527934.1
SORL1
sortilin-related receptor, L(DLR class) A repeats containing

Network of associatons between targets according to the STRING database.

First level regulatory network of OLIG3_NEUROD2_NEUROG2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0045799 mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) positive regulation of chromatin assembly or disassembly(GO:0045799) negative regulation of RNA export from nucleus(GO:0046832)
0.2 1.4 GO:0052551 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.2 1.0 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.2 2.2 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.1 0.6 GO:0016095 polyprenol catabolic process(GO:0016095)
0.1 0.4 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.3 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.5 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 0.3 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 0.5 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.1 1.7 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.7 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 0.3 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 0.4 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.1 0.5 GO:0070560 protein secretion by platelet(GO:0070560)
0.1 2.1 GO:0006068 ethanol catabolic process(GO:0006068)
0.1 0.3 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
0.1 0.4 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 0.2 GO:2000612 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.1 0.2 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.1 0.2 GO:0042560 folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.1 0.2 GO:1901143 insulin catabolic process(GO:1901143)
0.1 1.0 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 0.3 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 1.0 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.2 GO:1902997 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.1 2.1 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.2 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.4 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.5 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.2 GO:0046104 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0 0.2 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.5 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0 0.1 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.1 GO:0001694 histamine biosynthetic process(GO:0001694)
0.0 1.0 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.2 GO:1904073 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.0 0.3 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.2 GO:0033489 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0 0.4 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.6 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
0.0 0.2 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.3 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.2 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.0 0.1 GO:0001207 histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.0 1.1 GO:1904707 positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.0 0.2 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.2 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.0 0.1 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.0 0.1 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.2 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.0 0.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.5 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.1 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.0 0.1 GO:2001248 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 0.1 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.1 GO:0015853 adenine transport(GO:0015853)
0.0 0.1 GO:0043321 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.0 0.1 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.1 GO:0038188 cholecystokinin signaling pathway(GO:0038188)
0.0 0.1 GO:0046462 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.1 GO:0006533 aspartate catabolic process(GO:0006533)
0.0 0.2 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.1 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.1 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.0 0.1 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.1 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.1 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.0 0.1 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.0 0.1 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0051140 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.1 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 0.1 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 0.2 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.1 GO:0098976 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.4 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.1 GO:0061107 seminal vesicle development(GO:0061107)
0.0 0.1 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.0 0.2 GO:0036089 cleavage furrow formation(GO:0036089)
0.0 0.1 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.1 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.0 0.2 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:0060152 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.0 0.1 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.0 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.0 0.2 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:0009804 coumarin metabolic process(GO:0009804)
0.0 0.6 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.9 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.1 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.3 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.5 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.4 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.3 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.3 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.2 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.1 GO:0043418 homocysteine catabolic process(GO:0043418)
0.0 0.0 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.0 0.1 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.0 0.1 GO:0071504 cellular response to heparin(GO:0071504)
0.0 0.1 GO:0035811 negative regulation of urine volume(GO:0035811)
0.0 0.0 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.5 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.0 GO:0043324 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.1 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.1 GO:0019060 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.2 GO:0021859 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0 0.5 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.2 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.0 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.0 0.1 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.0 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.0 0.1 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.6 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.2 GO:2000194 regulation of female gonad development(GO:2000194)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 2.3 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.1 0.3 GO:0071001 U4/U6 snRNP(GO:0071001)
0.1 1.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.9 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.3 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.6 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.9 GO:0042588 zymogen granule(GO:0042588)
0.0 0.4 GO:0051286 cell tip(GO:0051286)
0.0 0.1 GO:0097441 basilar dendrite(GO:0097441)
0.0 0.6 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 1.6 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.7 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0097182 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.0 0.7 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.2 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.2 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.2 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.3 GO:0060091 kinocilium(GO:0060091)
0.0 0.6 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)
0.0 0.1 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.0 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.3 GO:0034709 methylosome(GO:0034709)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 0.4 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.7 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0000322 storage vacuole(GO:0000322)
0.0 0.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.1 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.3 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.1 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.1 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0005642 annulate lamellae(GO:0005642)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.2 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.3 1.1 GO:1904408 dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408)
0.1 1.0 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.6 GO:0047718 indanol dehydrogenase activity(GO:0047718)
0.1 0.4 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 0.4 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.1 0.4 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.4 GO:0050436 microfibril binding(GO:0050436)
0.1 2.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 0.2 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.1 1.7 GO:0070330 aromatase activity(GO:0070330)
0.1 0.3 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.1 0.3 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1 0.2 GO:0004137 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.1 0.2 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.1 0.3 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1 0.3 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.3 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.3 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 1.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.2 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.1 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.0 0.4 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.2 GO:0043559 insulin binding(GO:0043559)
0.0 0.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.1 GO:0005471 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.0 0.1 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.5 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.7 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.3 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.3 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 0.2 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.2 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 0.8 GO:0043495 protein anchor(GO:0043495)
0.0 2.0 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.8 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.2 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.7 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.1 GO:0004951 cholecystokinin receptor activity(GO:0004951)
0.0 0.5 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.1 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 0.1 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.0 0.3 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.1 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.4 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.5 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.7 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.8 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.0 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.0 0.1 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.1 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.0 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.1 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.0 0.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.1 GO:0044390 ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.0 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.0 0.0 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.5 GO:0030291 protein serine/threonine kinase inhibitor activity(GO:0030291)
0.0 0.1 GO:0033989 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
0.0 1.2 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 2.5 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.7 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.6 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.6 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.7 PID FANCONI PATHWAY Fanconi anemia pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 2.1 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 2.7 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.3 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.2 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.7 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.8 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.9 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.6 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.4 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.7 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.6 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 1.7 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.7 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.6 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 0.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.1 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.2 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription