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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for ONECUT1

Z-value: 1.05

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Transcription factors associated with ONECUT1

Gene Symbol Gene ID Gene Info
ENSG00000169856.7 one cut homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ONECUT1hg19_v2_chr15_-_53082178_53082209-0.331.0e-01Click!

Activity profile of ONECUT1 motif

Sorted Z-values of ONECUT1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr21_+_42792442 4.63 ENST00000398600.2
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr11_-_72385437 4.37 ENST00000418754.2
ENST00000542969.2
ENST00000334456.5
phosphodiesterase 2A, cGMP-stimulated
chr21_+_27011899 3.56 ENST00000425221.2
junctional adhesion molecule 2
chr3_-_79816965 3.15 ENST00000464233.1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr6_+_127898312 3.07 ENST00000329722.7
chromosome 6 open reading frame 58
chr12_-_76817036 2.99 ENST00000546946.1
oxysterol binding protein-like 8
chr7_-_115670792 2.11 ENST00000265440.7
ENST00000393485.1
transcription factor EC
chr11_+_19799327 2.09 ENST00000540292.1
neuron navigator 2
chr7_-_115670804 2.05 ENST00000320239.7
transcription factor EC
chr1_-_186649543 1.80 ENST00000367468.5
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr20_+_58515417 1.67 ENST00000360816.3
family with sequence similarity 217, member B
chr11_+_102188272 1.58 ENST00000532808.1
baculoviral IAP repeat containing 3
chr3_-_112693865 1.47 ENST00000471858.1
ENST00000295863.4
ENST00000308611.3
CD200 receptor 1
chr4_-_157892055 1.44 ENST00000422544.2
platelet derived growth factor C
chr14_-_27066960 1.40 ENST00000539517.2
neuro-oncological ventral antigen 1
chr4_-_157892167 1.34 ENST00000541126.1
platelet derived growth factor C
chr19_+_13135386 1.33 ENST00000360105.4
ENST00000588228.1
ENST00000591028.1
nuclear factor I/X (CCAAT-binding transcription factor)
chr7_-_69062391 1.27 ENST00000436600.2
RP5-942I16.1
chr19_+_45449301 1.25 ENST00000591597.1
apolipoprotein C-II
chr11_-_118305921 1.24 ENST00000532619.1
RP11-770J1.4
chr7_-_121944491 1.14 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZ family zinc finger 1
chr20_-_22559211 1.13 ENST00000564492.1
long intergenic non-protein coding RNA 261
chr10_+_60028818 1.13 ENST00000333926.5
CDGSH iron sulfur domain 1
chr4_-_157892498 1.12 ENST00000502773.1
platelet derived growth factor C
chr20_-_58515344 1.12 ENST00000370996.3
protein phosphatase 1, regulatory subunit 3D
chr11_+_131240373 1.12 ENST00000374791.3
ENST00000436745.1
neurotrimin
chr10_+_114133773 1.09 ENST00000354655.4
acyl-CoA synthetase long-chain family member 5
chr5_+_98109322 1.07 ENST00000513185.1
repulsive guidance molecule family member b
chr1_-_151804314 1.05 ENST00000318247.6
RAR-related orphan receptor C
chr15_-_64338521 1.04 ENST00000457488.1
ENST00000558069.1
death-associated protein kinase 2
chr15_-_89089860 1.04 ENST00000558413.1
ENST00000564406.1
ENST00000268148.8
de-etiolated homolog 1 (Arabidopsis)
chr13_-_46679144 1.02 ENST00000181383.4
carboxypeptidase B2 (plasma)
chr13_-_46679185 1.01 ENST00000439329.3
carboxypeptidase B2 (plasma)
chr12_+_111471828 0.99 ENST00000261726.6
cut-like homeobox 2
chr3_+_101546827 0.97 ENST00000461724.1
ENST00000483180.1
ENST00000394054.2
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr11_-_19223523 0.95 ENST00000265968.3
cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr11_+_62623544 0.94 ENST00000377890.2
ENST00000377891.2
ENST00000377889.2
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr11_+_62623621 0.89 ENST00000535296.1
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr1_-_151804222 0.86 ENST00000392697.3
RAR-related orphan receptor C
chr8_+_82192501 0.85 ENST00000297258.6
fatty acid binding protein 5 (psoriasis-associated)
chrX_+_122318113 0.85 ENST00000371264.3
glutamate receptor, ionotropic, AMPA 3
chr22_+_39101728 0.85 ENST00000216044.5
ENST00000484657.1
GTP binding protein 1
chr19_-_47287990 0.83 ENST00000593713.1
ENST00000598022.1
ENST00000434726.2
solute carrier family 1 (neutral amino acid transporter), member 5
chr14_+_74058410 0.83 ENST00000326303.4
acyl-CoA thioesterase 4
chr3_-_191000172 0.82 ENST00000427544.2
urotensin 2B
chr3_-_164914640 0.80 ENST00000241274.3
SLIT and NTRK-like family, member 3
chr17_-_79876010 0.79 ENST00000328666.6
sirtuin 7
chr15_-_88799661 0.79 ENST00000360948.2
ENST00000357724.2
ENST00000355254.2
ENST00000317501.3
neurotrophic tyrosine kinase, receptor, type 3
chr11_+_60467047 0.77 ENST00000300226.2
membrane-spanning 4-domains, subfamily A, member 8
chr10_-_4285923 0.76 ENST00000418372.1
ENST00000608792.1
long intergenic non-protein coding RNA 702
chr1_+_50569575 0.72 ENST00000371827.1
ELAV like neuron-specific RNA binding protein 4
chr3_-_46735132 0.70 ENST00000415953.1
ALS2 C-terminal like
chr3_-_24207039 0.70 ENST00000280696.5
thyroid hormone receptor, beta
chr14_-_74892805 0.69 ENST00000331628.3
ENST00000554953.1
synapse differentiation inducing 1-like
chr16_+_31044413 0.68 ENST00000394998.1
syntaxin 4
chr3_+_32859510 0.68 ENST00000383763.5
tripartite motif containing 71, E3 ubiquitin protein ligase
chr2_-_197457335 0.67 ENST00000260983.3
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr12_-_21487829 0.67 ENST00000445053.1
ENST00000452078.1
ENST00000458504.1
ENST00000422327.1
ENST00000421294.1
solute carrier organic anion transporter family, member 1A2
chr22_+_51176624 0.66 ENST00000216139.5
ENST00000529621.1
acrosin
chr1_+_212738676 0.66 ENST00000366981.4
ENST00000366987.2
activating transcription factor 3
chr5_-_20575959 0.65 ENST00000507958.1
cadherin 18, type 2
chr1_+_10292308 0.63 ENST00000377081.1
kinesin family member 1B
chr14_-_27066636 0.62 ENST00000267422.7
ENST00000344429.5
ENST00000574031.1
ENST00000465357.2
ENST00000547619.1
neuro-oncological ventral antigen 1
chr11_-_5531215 0.60 ENST00000311659.4
ubiquilin 3
chr1_-_26633067 0.60 ENST00000421827.2
ENST00000374215.1
ENST00000374223.1
ENST00000357089.4
ENST00000535108.1
ENST00000314675.7
ENST00000436301.2
ENST00000423664.1
ENST00000374221.3
UBX domain protein 11
chr9_-_2844058 0.59 ENST00000397885.2
KIAA0020
chr12_-_95941987 0.59 ENST00000537435.2
ubiquitin specific peptidase 44
chr17_+_41052808 0.59 ENST00000592383.1
ENST00000253801.2
ENST00000585489.1
glucose-6-phosphatase, catalytic subunit
chr19_+_45449228 0.58 ENST00000252490.4
apolipoprotein C-II
chr19_+_45449266 0.55 ENST00000592257.1
apolipoprotein C-II
chr3_+_98699880 0.55 ENST00000473756.1
long intergenic non-protein coding RNA 973
chr20_+_36373032 0.55 ENST00000373473.1
catenin, beta like 1
chr2_+_27255806 0.54 ENST00000238788.9
ENST00000404032.3
transmembrane protein 214
chr19_+_46800289 0.54 ENST00000377670.4
hypoxia inducible factor 3, alpha subunit
chr17_+_56232494 0.53 ENST00000268912.5
olfactory receptor, family 4, subfamily D, member 1
chr10_+_97759848 0.53 ENST00000424464.1
ENST00000410012.2
ENST00000344386.3
coiled-coil and C2 domain containing 2B
chr18_-_49557 0.53 ENST00000308911.6
Tubulin beta-8 chain-like protein LOC260334
chr12_+_21679220 0.52 ENST00000256969.2
chromosome 12 open reading frame 39
chr4_+_107237660 0.51 ENST00000394701.4
aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
chr3_-_46735155 0.50 ENST00000318962.4
ALS2 C-terminal like
chr2_-_161350305 0.50 ENST00000348849.3
RNA binding motif, single stranded interacting protein 1
chr11_-_126870655 0.49 ENST00000525144.2
kin of IRRE like 3 (Drosophila)
chr10_-_46167722 0.49 ENST00000374366.3
ENST00000344646.5
zinc finger, AN1-type domain 4
chr7_+_141463897 0.48 ENST00000247879.2
taste receptor, type 2, member 3
chr8_-_23712312 0.47 ENST00000290271.2
stanniocalcin 1
chr4_-_111563076 0.47 ENST00000354925.2
ENST00000511990.1
paired-like homeodomain 2
chr5_-_75008244 0.46 ENST00000510798.1
ENST00000446329.2
POC5 centriolar protein
chr3_+_181429704 0.46 ENST00000431565.2
ENST00000325404.1
SRY (sex determining region Y)-box 2
chr10_-_102046098 0.44 ENST00000441611.1
biogenesis of lysosomal organelles complex-1, subunit 2
chr10_-_102046417 0.44 ENST00000370372.2
biogenesis of lysosomal organelles complex-1, subunit 2
chr1_-_177939348 0.43 ENST00000464631.2
SEC16 homolog B (S. cerevisiae)
chr15_+_31196080 0.43 ENST00000561607.1
ENST00000565466.1
FANCD2/FANCI-associated nuclease 1
chr5_-_115910630 0.43 ENST00000343348.6
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr11_+_118938485 0.42 ENST00000300793.6
vacuolar protein sorting 11 homolog (S. cerevisiae)
chr5_-_60458179 0.42 ENST00000507416.1
ENST00000339020.3
small integral membrane protein 15
chr5_-_171881491 0.42 ENST00000311601.5
SH3 and PX domains 2B
chr13_+_30002741 0.42 ENST00000380808.2
microtubule associated tumor suppressor candidate 2
chr17_-_39216344 0.41 ENST00000391418.2
keratin associated protein 2-3
chr12_-_11422739 0.41 ENST00000279573.7
proline-rich protein BstNI subfamily 3
chr11_+_4788500 0.40 ENST00000380390.1
matrix metallopeptidase 26
chr3_+_108308513 0.40 ENST00000361582.3
DAZ interacting zinc finger protein 3
chr7_+_97736197 0.40 ENST00000297293.5
lemur tyrosine kinase 2
chr7_+_148844516 0.39 ENST00000420008.2
ENST00000475153.1
zinc finger protein 398
chr16_+_27214802 0.39 ENST00000380948.2
ENST00000286096.4
lysine (K)-specific demethylase 8
chr9_+_130565487 0.39 ENST00000373225.3
ENST00000431857.1
folylpolyglutamate synthase
chr10_-_94003003 0.38 ENST00000412050.4
cytoplasmic polyadenylation element binding protein 3
chr2_+_89986318 0.37 ENST00000491977.1
immunoglobulin kappa variable 2D-29
chr1_+_26496362 0.37 ENST00000374266.5
ENST00000270812.5
zinc finger protein 593
chr10_-_95209 0.37 ENST00000332708.5
ENST00000309812.4
tubulin, beta 8 class VIII
chr18_+_11490077 0.37 ENST00000586947.1
ENST00000591431.1
RP11-712C7.1
chr1_+_50571949 0.36 ENST00000357083.4
ELAV like neuron-specific RNA binding protein 4
chr1_-_116383322 0.36 ENST00000429731.1
nescient helix loop helix 2
chr1_+_25598989 0.36 ENST00000454452.2
Rh blood group, D antigen
chr6_+_27925019 0.35 ENST00000244623.1
olfactory receptor, family 2, subfamily B, member 6
chr12_-_11422630 0.34 ENST00000381842.3
ENST00000538488.1
proline-rich protein BstNI subfamily 3
chr6_+_29079668 0.34 ENST00000377169.1
olfactory receptor, family 2, subfamily J, member 3
chr7_-_152373216 0.34 ENST00000359321.1
X-ray repair complementing defective repair in Chinese hamster cells 2
chrX_-_70326455 0.34 ENST00000374251.5
chromosome X open reading frame 65
chr7_-_6523688 0.34 ENST00000490996.1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr13_+_52598827 0.33 ENST00000521776.2
UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)
chr1_+_78245303 0.33 ENST00000370791.3
ENST00000443751.2
family with sequence similarity 73, member A
chr22_-_37505588 0.33 ENST00000406856.1
transmembrane protease, serine 6
chr6_+_116782527 0.33 ENST00000368606.3
ENST00000368605.1
family with sequence similarity 26, member F
chr16_-_69788816 0.33 ENST00000268802.5
NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
chr5_+_169780485 0.32 ENST00000377360.4
Kv channel interacting protein 1
chr17_-_64225508 0.32 ENST00000205948.6
apolipoprotein H (beta-2-glycoprotein I)
chr2_-_214016314 0.32 ENST00000434687.1
ENST00000374319.4
IKAROS family zinc finger 2 (Helios)
chr3_-_52273098 0.32 ENST00000499914.2
ENST00000305533.5
ENST00000597542.1
twinfilin actin-binding protein 2
toll-like receptor 9
chr1_-_32384693 0.31 ENST00000602683.1
ENST00000470404.1
protein tyrosine phosphatase type IVA, member 2
chr1_-_116383738 0.31 ENST00000320238.3
nescient helix loop helix 2
chr22_-_37505449 0.31 ENST00000406725.1
transmembrane protease, serine 6
chr1_+_86934526 0.31 ENST00000394711.1
chloride channel accessory 1
chr19_-_49243845 0.30 ENST00000222145.4
Ras interacting protein 1
chr19_+_45596398 0.30 ENST00000544069.2
protein phosphatase 1, regulatory subunit 37
chr13_-_36920420 0.30 ENST00000438666.2
spastic paraplegia 20 (Troyer syndrome)
chr16_-_75467318 0.30 ENST00000283882.3
craniofacial development protein 1
chr5_+_42756903 0.30 ENST00000361970.5
ENST00000388827.4
coiled-coil domain containing 152
chr10_+_98064085 0.29 ENST00000419175.1
ENST00000371174.2
DNA nucleotidylexotransferase
chr1_+_113933371 0.29 ENST00000369617.4
membrane associated guanylate kinase, WW and PDZ domain containing 3
chr11_-_47788847 0.29 ENST00000263773.5
formin binding protein 4
chr22_-_32146106 0.29 ENST00000327423.6
ENST00000397493.2
ENST00000434485.1
ENST00000412743.1
proline rich 14-like
chrX_+_70435044 0.29 ENST00000374029.1
ENST00000374022.3
ENST00000447581.1
gap junction protein, beta 1, 32kDa
chr18_-_31802282 0.28 ENST00000535475.1
nucleolar protein 4
chr3_-_170744498 0.28 ENST00000382808.4
ENST00000314251.3
solute carrier family 2 (facilitated glucose transporter), member 2
chr2_-_172967621 0.28 ENST00000234198.4
ENST00000466293.2
distal-less homeobox 2
chr1_-_202679535 0.27 ENST00000367268.4
synaptotagmin II
chrX_+_49126294 0.27 ENST00000466508.1
ENST00000438316.1
ENST00000055335.6
ENST00000495799.1
protein phosphatase 1, regulatory subunit 3F
chr1_+_156589051 0.27 ENST00000255039.1
hyaluronan and proteoglycan link protein 2
chr4_+_169418195 0.26 ENST00000261509.6
ENST00000335742.7
palladin, cytoskeletal associated protein
chr2_-_161349909 0.26 ENST00000392753.3
RNA binding motif, single stranded interacting protein 1
chr1_-_197036364 0.26 ENST00000367412.1
coagulation factor XIII, B polypeptide
chr14_+_37131058 0.26 ENST00000361487.6
paired box 9
chr2_-_39348137 0.25 ENST00000426016.1
son of sevenless homolog 1 (Drosophila)
chr2_+_241375069 0.25 ENST00000264039.2
glypican 1
chr17_-_56082455 0.25 ENST00000578794.1
Uncharacterized protein
chr1_-_159684371 0.24 ENST00000255030.5
ENST00000437342.1
ENST00000368112.1
ENST00000368111.1
ENST00000368110.1
ENST00000343919.2
C-reactive protein, pentraxin-related
chr8_-_70983506 0.24 ENST00000276594.2
PR domain containing 14
chr15_-_38519066 0.24 ENST00000561320.1
ENST00000561161.1
RP11-346D14.1
chr8_+_120885949 0.24 ENST00000523492.1
ENST00000286234.5
DEP domain containing MTOR-interacting protein
chr2_+_108602971 0.24 ENST00000409059.1
ENST00000540517.1
ENST00000264047.2
solute carrier family 5 (sodium/choline cotransporter), member 7
chr19_+_45596218 0.24 ENST00000421905.1
ENST00000221462.4
protein phosphatase 1, regulatory subunit 37
chr9_+_140135665 0.23 ENST00000340384.4
tubulin, beta 4B class IVb
chrX_+_135388147 0.23 ENST00000394141.1
G protein-coupled receptor 112
chr4_+_71091786 0.22 ENST00000317987.5
follicular dendritic cell secreted protein
chr15_-_99789736 0.22 ENST00000560235.1
ENST00000394132.2
ENST00000560860.1
ENST00000558078.1
ENST00000394136.1
ENST00000262074.4
ENST00000558613.1
ENST00000394130.1
ENST00000560772.1
tetratricopeptide repeat domain 23
chr3_+_186383741 0.22 ENST00000232003.4
histidine-rich glycoprotein
chr9_+_95726243 0.22 ENST00000416701.2
FYVE, RhoGEF and PH domain containing 3
chrX_-_151143140 0.22 ENST00000393914.3
ENST00000370328.3
ENST00000370325.1
gamma-aminobutyric acid (GABA) A receptor, epsilon
chr19_+_2785458 0.21 ENST00000307741.6
ENST00000585338.1
thimet oligopeptidase 1
chr3_+_148415571 0.21 ENST00000497524.1
ENST00000349243.3
ENST00000542281.1
ENST00000418473.2
ENST00000404754.2
angiotensin II receptor, type 1
chr18_+_49866496 0.21 ENST00000442544.2
deleted in colorectal carcinoma
chrX_-_110654147 0.21 ENST00000358070.4
doublecortin
chr5_-_151784838 0.21 ENST00000255262.3
neuromedin U receptor 2
chr4_-_103747011 0.20 ENST00000350435.7
ubiquitin-conjugating enzyme E2D 3
chr10_+_51576285 0.19 ENST00000443446.1
nuclear receptor coactivator 4
chrX_+_122318006 0.19 ENST00000371266.1
ENST00000264357.5
glutamate receptor, ionotropic, AMPA 3
chr8_-_33370607 0.19 ENST00000360742.5
ENST00000523305.1
TELO2 interacting protein 2
chr18_-_31802056 0.18 ENST00000538587.1
nucleolar protein 4
chr12_+_15475462 0.18 ENST00000543886.1
ENST00000348962.2
protein tyrosine phosphatase, receptor type, O
chr11_+_60995849 0.17 ENST00000537932.1
pepsinogen 4, group I (pepsinogen A)
chr1_+_57320437 0.17 ENST00000361249.3
complement component 8, alpha polypeptide
chr2_+_234959376 0.17 ENST00000425558.1
secreted phosphoprotein 2, 24kDa
chr6_-_46048116 0.17 ENST00000185206.6
chloride intracellular channel 5
chr7_-_154794763 0.17 ENST00000404141.1
PAX interacting (with transcription-activation domain) protein 1
chr11_-_10828892 0.17 ENST00000525681.1
eukaryotic translation initiation factor 4 gamma, 2
chr3_+_188889737 0.16 ENST00000345063.3
tumor protein p63 regulated 1
chr1_+_156756667 0.15 ENST00000526188.1
ENST00000454659.1
papillary renal cell carcinoma (translocation-associated)
chr1_+_145301735 0.15 ENST00000605176.1
neuroblastoma breakpoint family, member 10
chr19_-_46916805 0.15 ENST00000307522.3
coiled-coil domain containing 8
chr5_-_135701164 0.15 ENST00000355180.3
ENST00000426057.2
ENST00000513104.1
transient receptor potential cation channel, subfamily C, member 7
chrX_+_14547632 0.14 ENST00000218075.4
glycine receptor, alpha 2
chrX_-_131262048 0.14 ENST00000298542.4
FERM domain containing 7
chr11_-_95657231 0.14 ENST00000409459.1
ENST00000352297.7
ENST00000393223.3
ENST00000346299.5
myotubularin related protein 2
chr13_-_86373536 0.14 ENST00000400286.2
SLIT and NTRK-like family, member 6
chr3_-_112693759 0.14 ENST00000440122.2
ENST00000490004.1
CD200 receptor 1
chr17_-_50235423 0.14 ENST00000340813.6
carbonic anhydrase X
chr20_+_23471727 0.14 ENST00000449810.1
ENST00000246012.1
cystatin 8 (cystatin-related epididymal specific)
chr8_-_101719159 0.13 ENST00000520868.1
ENST00000522658.1
poly(A) binding protein, cytoplasmic 1
chr6_-_133055815 0.13 ENST00000509351.1
ENST00000417437.2
ENST00000414302.2
ENST00000423615.2
ENST00000427187.2
ENST00000275223.3
ENST00000519686.2
vanin 3
chr1_+_17575584 0.13 ENST00000375460.3
peptidyl arginine deiminase, type III

Network of associatons between targets according to the STRING database.

First level regulatory network of ONECUT1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.4 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
1.0 3.1 GO:0021823 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.6 1.8 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.6 2.4 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
0.5 2.0 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.4 4.6 GO:0003373 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.4 1.8 GO:0060356 leucine import(GO:0060356)
0.3 0.8 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.3 0.8 GO:0048687 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.2 3.0 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.2 0.9 GO:0019605 butyrate metabolic process(GO:0019605)
0.2 0.7 GO:0008050 female courtship behavior(GO:0008050)
0.2 2.1 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.2 0.7 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.2 0.7 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.2 0.8 GO:0010585 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.2 1.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.2 1.0 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.2 0.9 GO:0035995 detection of muscle stretch(GO:0035995)
0.2 0.6 GO:1904647 response to rotenone(GO:1904647)
0.2 0.5 GO:0021763 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.1 3.8 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1 1.6 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.1 0.4 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1 0.4 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.1 0.7 GO:0007341 penetration of zona pellucida(GO:0007341)
0.1 0.3 GO:0021893 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.1 1.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 0.3 GO:1901895 positive regulation of interferon-alpha biosynthetic process(GO:0045356) negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.1 1.9 GO:0036315 cellular response to sterol(GO:0036315)
0.1 0.3 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.1 0.4 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.1 0.2 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.1 0.3 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.1 0.2 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.1 0.2 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.1 0.9 GO:0060155 platelet dense granule organization(GO:0060155)
0.1 0.2 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 0.2 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.1 0.3 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.1 0.6 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.2 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1 0.5 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 0.2 GO:1904693 midbrain morphogenesis(GO:1904693)
0.0 0.2 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.5 GO:0002118 aggressive behavior(GO:0002118)
0.0 1.0 GO:0007614 short-term memory(GO:0007614)
0.0 0.5 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.6 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
0.0 0.4 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.7 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.4 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 1.1 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.0 0.3 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 1.1 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.3 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 1.1 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.6 GO:0097264 self proteolysis(GO:0097264)
0.0 0.3 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.0 0.2 GO:1900619 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0 0.1 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.4 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.7 GO:0044705 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0 0.3 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.6 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.4 GO:0070863 peroxisome fission(GO:0016559) positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.1 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 1.1 GO:0008038 neuron recognition(GO:0008038)
0.0 1.0 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.2 GO:0032930 positive regulation of superoxide anion generation(GO:0032930)
0.0 0.4 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 0.2 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.9 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.2 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.3 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.0 3.4 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.1 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.1 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.3 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.1 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.7 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 1.2 GO:0007032 endosome organization(GO:0007032)
0.0 0.7 GO:0030071 regulation of mitotic metaphase/anaphase transition(GO:0030071)
0.0 0.5 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.0 0.2 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.3 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.0 1.1 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.4 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.2 0.7 GO:0043159 acrosomal matrix(GO:0043159)
0.2 0.7 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 1.1 GO:0042587 glycogen granule(GO:0042587)
0.1 0.5 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
0.1 2.1 GO:0005614 interstitial matrix(GO:0005614)
0.1 1.0 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 0.7 GO:0000322 storage vacuole(GO:0000322)
0.1 0.4 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.8 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.3 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.3 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.9 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.5 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.4 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 3.7 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.3 GO:0032009 early phagosome(GO:0032009)
0.0 0.4 GO:0030897 HOPS complex(GO:0030897)
0.0 1.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.1 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 1.1 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 3.9 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.2 GO:0097486 multivesicular body lumen(GO:0097486)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 1.8 GO:0005901 caveola(GO:0005901)
0.0 7.3 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.6 GO:1904115 axon cytoplasm(GO:1904115)
0.0 2.4 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 1.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.2 GO:0044754 autolysosome(GO:0044754)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 1.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.7 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 2.5 GO:0005741 mitochondrial outer membrane(GO:0005741) organelle outer membrane(GO:0031968)
0.0 1.0 GO:0005776 autophagosome(GO:0005776)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.4 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.4 1.8 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.4 3.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.4 2.7 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.3 0.8 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.2 1.9 GO:0008142 oxysterol binding(GO:0008142)
0.2 0.7 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.2 0.5 GO:0070336 flap-structured DNA binding(GO:0070336)
0.2 0.7 GO:0004040 amidase activity(GO:0004040)
0.1 0.6 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 3.9 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 0.4 GO:0031177 acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)
0.1 0.8 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 1.8 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.3 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 0.5 GO:0033265 choline binding(GO:0033265)
0.1 3.0 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 0.3 GO:0005046 KDEL sequence binding(GO:0005046)
0.1 0.3 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1 0.9 GO:0031433 telethonin binding(GO:0031433)
0.1 0.2 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 0.3 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.1 0.7 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 1.0 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 0.8 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 1.1 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 0.8 GO:0005030 GPI-linked ephrin receptor activity(GO:0005004) neurotrophin receptor activity(GO:0005030)
0.1 2.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 1.1 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.9 GO:0035198 miRNA binding(GO:0035198)
0.0 1.5 GO:0017091 AU-rich element binding(GO:0017091)
0.0 1.6 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.3 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.7 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 0.3 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.9 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:0043532 angiostatin binding(GO:0043532)
0.0 1.1 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.5 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.5 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 1.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.1 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.2 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.8 GO:0005504 fatty acid binding(GO:0005504)
0.0 5.1 GO:0008017 microtubule binding(GO:0008017)
0.0 0.3 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 2.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.3 GO:0008494 translation activator activity(GO:0008494)
0.0 0.4 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 3.6 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 1.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 1.1 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 3.6 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 1.6 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 2.9 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 3.6 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.1 PID SHP2 PATHWAY SHP2 signaling
0.0 0.9 PID BMP PATHWAY BMP receptor signaling
0.0 0.5 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.4 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.2 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.7 PID AP1 PATHWAY AP-1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.9 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.2 3.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 2.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 4.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 1.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 2.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 4.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.7 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 1.1 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.0 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 1.0 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.0 0.5 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 3.7 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 1.2 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 2.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.2 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.9 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.8 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.7 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.5 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.6 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport