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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for OSR1_OSR2

Z-value: 0.66

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Transcription factors associated with OSR1_OSR2

Gene Symbol Gene ID Gene Info
OSR1
ENSG00000143867.5 odd-skipped related transcription factor 1
OSR2
ENSG00000164920.5 odd-skipped related transciption factor 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
OSR2hg19_v2_chr8_+_99956759_99956887-0.144.9e-01Click!
OSR1hg19_v2_chr2_-_19558373_19558414-0.067.7e-01Click!

Activity profile of OSR1_OSR2 motif

Sorted Z-values of OSR1_OSR2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_193853927 2.73 ENST00000232424.3
HES1
hes family bHLH transcription factor 1
chr4_-_186696425 2.27 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
SORBS2
sorbin and SH3 domain containing 2
chr2_-_183387430 1.96 ENST00000410103.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr4_-_186697044 1.88 ENST00000437304.2
SORBS2
sorbin and SH3 domain containing 2
chr13_-_72441315 1.75 ENST00000305425.4
ENST00000313174.7
ENST00000354591.4
DACH1
dachshund homolog 1 (Drosophila)
chr2_-_183387064 1.47 ENST00000536095.1
ENST00000331935.6
ENST00000358139.2
ENST00000456212.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr4_+_39460689 1.30 ENST00000381846.1
LIAS
lipoic acid synthetase
chr21_+_45993606 1.20 ENST00000400374.3
KRTAP10-4
keratin associated protein 10-4
chr3_+_45927994 1.18 ENST00000357632.2
ENST00000395963.2
CCR9
chemokine (C-C motif) receptor 9
chr1_+_97187318 1.11 ENST00000609116.1
ENST00000370198.1
ENST00000370197.1
ENST00000426398.2
ENST00000394184.3
PTBP2
polypyrimidine tract binding protein 2
chr12_+_27396901 1.10 ENST00000541191.1
ENST00000389032.3
STK38L
serine/threonine kinase 38 like
chr4_+_39460659 1.06 ENST00000513731.1
LIAS
lipoic acid synthetase
chr13_-_52980263 0.97 ENST00000258613.4
ENST00000544466.1
THSD1
thrombospondin, type I, domain containing 1
chr17_-_46690839 0.89 ENST00000498634.2
HOXB8
homeobox B8
chr4_+_145567173 0.85 ENST00000296575.3
HHIP
hedgehog interacting protein
chr1_-_59043166 0.82 ENST00000371225.2
TACSTD2
tumor-associated calcium signal transducer 2
chr2_+_234959323 0.79 ENST00000373368.1
ENST00000168148.3
SPP2
secreted phosphoprotein 2, 24kDa
chr12_-_15114492 0.78 ENST00000541546.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr21_-_31744557 0.77 ENST00000399889.2
KRTAP13-2
keratin associated protein 13-2
chr12_-_15114658 0.74 ENST00000542276.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr2_-_183387283 0.65 ENST00000435564.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr2_-_44588679 0.65 ENST00000409411.1
PREPL
prolyl endopeptidase-like
chr2_-_44588694 0.64 ENST00000409957.1
PREPL
prolyl endopeptidase-like
chr4_+_145567297 0.63 ENST00000434550.2
HHIP
hedgehog interacting protein
chr2_-_44588624 0.63 ENST00000438314.1
ENST00000409936.1
PREPL
prolyl endopeptidase-like
chr12_-_15114603 0.60 ENST00000228945.4
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr21_-_31859755 0.56 ENST00000334055.3
KRTAP19-2
keratin associated protein 19-2
chr16_-_31439735 0.55 ENST00000287490.4
COX6A2
cytochrome c oxidase subunit VIa polypeptide 2
chr8_+_96037255 0.53 ENST00000286687.4
NDUFAF6
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr8_+_37594130 0.53 ENST00000518526.1
ENST00000523887.1
ENST00000276461.5
ERLIN2
ER lipid raft associated 2
chr2_+_87754989 0.50 ENST00000409898.2
ENST00000419680.2
ENST00000414584.1
ENST00000455131.1
LINC00152
long intergenic non-protein coding RNA 152
chr15_-_42076229 0.50 ENST00000597767.1
AC073657.1
Uncharacterized protein
chr2_+_87754887 0.49 ENST00000409054.1
ENST00000331944.6
ENST00000409139.1
LINC00152
long intergenic non-protein coding RNA 152
chr8_+_26247878 0.47 ENST00000518611.1
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr1_+_156561533 0.46 ENST00000368234.3
ENST00000368235.3
ENST00000368233.3
APOA1BP
apolipoprotein A-I binding protein
chr5_+_36152163 0.46 ENST00000274255.6
SKP2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr1_-_179112189 0.45 ENST00000512653.1
ENST00000344730.3
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr11_+_64808675 0.45 ENST00000529996.1
SAC3D1
SAC3 domain containing 1
chr2_+_87755054 0.45 ENST00000423846.1
LINC00152
long intergenic non-protein coding RNA 152
chr13_-_52703187 0.44 ENST00000355568.4
NEK5
NIMA-related kinase 5
chr19_-_52391142 0.44 ENST00000446514.1
ENST00000458390.1
ENST00000420592.1
ENST00000451628.2
ENST00000592321.1
ENST00000591320.1
ENST00000412216.1
ENST00000301399.5
ZNF577
zinc finger protein 577
chr14_+_21152706 0.44 ENST00000397995.2
ENST00000304704.4
ENST00000553909.1
RNASE4
AL163636.6
ribonuclease, RNase A family, 4
Homo sapiens ribonuclease, RNase A family, 4 (RNASE4), transcript variant 4, mRNA.
chr22_-_26986045 0.42 ENST00000442495.1
ENST00000440953.1
ENST00000450022.1
ENST00000338754.4
TPST2
tyrosylprotein sulfotransferase 2
chr5_+_36152091 0.41 ENST00000274254.5
SKP2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr16_-_68033356 0.40 ENST00000393847.1
ENST00000573808.1
ENST00000572624.1
DPEP2
dipeptidase 2
chr6_+_152011628 0.39 ENST00000404742.1
ENST00000440973.1
ESR1
estrogen receptor 1
chr20_-_1472029 0.36 ENST00000359801.3
SIRPB2
signal-regulatory protein beta 2
chr2_-_201828356 0.35 ENST00000234296.2
ORC2
origin recognition complex, subunit 2
chr14_+_21152259 0.35 ENST00000555835.1
ENST00000336811.6
RNASE4
ANG
ribonuclease, RNase A family, 4
angiogenin, ribonuclease, RNase A family, 5
chr1_+_201798269 0.35 ENST00000361565.4
IPO9
importin 9
chr7_+_63361201 0.34 ENST00000450544.1
RP11-340I6.8
RP11-340I6.8
chrX_-_134049233 0.34 ENST00000370779.4
MOSPD1
motile sperm domain containing 1
chrX_-_134478012 0.34 ENST00000370766.3
ZNF75D
zinc finger protein 75D
chr3_+_179322481 0.34 ENST00000259037.3
NDUFB5
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
chr8_-_120605194 0.34 ENST00000522167.1
ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr2_+_178257372 0.33 ENST00000264167.4
ENST00000409888.1
AGPS
alkylglycerone phosphate synthase
chr14_+_93651296 0.33 ENST00000283534.4
ENST00000557574.1
TMEM251
RP11-371E8.4
transmembrane protein 251
Uncharacterized protein
chr2_-_44588893 0.33 ENST00000409272.1
ENST00000410081.1
ENST00000541738.1
PREPL
prolyl endopeptidase-like
chr7_-_123197733 0.32 ENST00000470123.1
ENST00000471770.1
NDUFA5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr14_-_88459503 0.32 ENST00000393568.4
ENST00000261304.2
GALC
galactosylceramidase
chr14_-_88459182 0.31 ENST00000544807.2
GALC
galactosylceramidase
chr8_-_99306611 0.30 ENST00000341166.3
NIPAL2
NIPA-like domain containing 2
chr2_+_44589036 0.28 ENST00000402247.1
ENST00000407131.1
ENST00000403853.3
ENST00000378494.3
CAMKMT
calmodulin-lysine N-methyltransferase
chr20_+_10415931 0.28 ENST00000334534.5
SLX4IP
SLX4 interacting protein
chr17_-_72869140 0.27 ENST00000583917.1
ENST00000293195.5
ENST00000442102.2
FDXR
ferredoxin reductase
chr6_+_122720681 0.26 ENST00000368455.4
ENST00000452194.1
HSF2
heat shock transcription factor 2
chr14_+_56127989 0.26 ENST00000555573.1
KTN1
kinectin 1 (kinesin receptor)
chr1_-_179112173 0.26 ENST00000408940.3
ENST00000504405.1
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr4_+_6576895 0.26 ENST00000285599.3
ENST00000504248.1
ENST00000505907.1
MAN2B2
mannosidase, alpha, class 2B, member 2
chr5_-_36152031 0.26 ENST00000296603.4
LMBRD2
LMBR1 domain containing 2
chr20_-_33999766 0.26 ENST00000349714.5
ENST00000438533.1
ENST00000359226.2
ENST00000374384.2
ENST00000374377.5
ENST00000407996.2
ENST00000424405.1
ENST00000542501.1
ENST00000397554.1
ENST00000540457.1
ENST00000374380.2
ENST00000374385.5
UQCC1
ubiquinol-cytochrome c reductase complex assembly factor 1
chr1_+_89829610 0.26 ENST00000370456.4
ENST00000535065.1
GBP6
guanylate binding protein family, member 6
chr15_+_41523335 0.25 ENST00000334660.5
CHP1
calcineurin-like EF-hand protein 1
chr17_-_72869086 0.25 ENST00000581530.1
ENST00000420580.2
ENST00000455107.2
ENST00000413947.2
ENST00000581219.1
ENST00000582944.1
FDXR
ferredoxin reductase
chr12_+_94656297 0.23 ENST00000545312.1
PLXNC1
plexin C1
chr16_+_3550924 0.23 ENST00000576634.1
ENST00000574369.1
ENST00000341633.5
ENST00000417763.2
ENST00000571025.1
CLUAP1
clusterin associated protein 1
chr22_+_39795746 0.23 ENST00000216160.6
ENST00000331454.3
TAB1
TGF-beta activated kinase 1/MAP3K7 binding protein 1
chr2_+_70056762 0.23 ENST00000282570.3
GMCL1
germ cell-less, spermatogenesis associated 1
chr19_-_17185848 0.23 ENST00000593360.1
HAUS8
HAUS augmin-like complex, subunit 8
chr1_-_231560790 0.23 ENST00000366641.3
EGLN1
egl-9 family hypoxia-inducible factor 1
chr2_+_234959376 0.23 ENST00000425558.1
SPP2
secreted phosphoprotein 2, 24kDa
chr8_-_37594944 0.23 ENST00000330539.1
RP11-863K10.7
Uncharacterized protein
chr1_+_42922173 0.22 ENST00000455780.1
ENST00000372560.3
ENST00000372561.3
ENST00000372556.3
PPCS
phosphopantothenoylcysteine synthetase
chr14_-_39417410 0.21 ENST00000557019.1
ENST00000556116.1
ENST00000554732.1
LINC00639
long intergenic non-protein coding RNA 639
chr17_+_60758814 0.21 ENST00000579432.1
ENST00000446119.2
MRC2
mannose receptor, C type 2
chrX_+_80457442 0.21 ENST00000373212.5
SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chr7_-_6312206 0.20 ENST00000350796.3
CYTH3
cytohesin 3
chr11_+_43380459 0.19 ENST00000299240.6
ENST00000039989.4
TTC17
tetratricopeptide repeat domain 17
chr19_-_18197799 0.19 ENST00000430026.3
ENST00000593993.2
IL12RB1
interleukin 12 receptor, beta 1
chr8_+_125486939 0.19 ENST00000303545.3
RNF139
ring finger protein 139
chr19_+_36203830 0.18 ENST00000262630.3
ZBTB32
zinc finger and BTB domain containing 32
chr12_-_123201337 0.18 ENST00000528880.2
HCAR3
hydroxycarboxylic acid receptor 3
chrY_-_6742068 0.17 ENST00000215479.5
AMELY
amelogenin, Y-linked
chr16_-_8962200 0.17 ENST00000562843.1
ENST00000561530.1
ENST00000396593.2
CARHSP1
calcium regulated heat stable protein 1, 24kDa
chr5_-_147211226 0.17 ENST00000296695.5
SPINK1
serine peptidase inhibitor, Kazal type 1
chr3_+_156799587 0.17 ENST00000469196.1
RP11-6F2.5
RP11-6F2.5
chr9_-_34710066 0.16 ENST00000378792.1
ENST00000259607.2
CCL21
chemokine (C-C motif) ligand 21
chr15_+_41523417 0.16 ENST00000560397.1
CHP1
calcineurin-like EF-hand protein 1
chr1_+_161736072 0.16 ENST00000367942.3
ATF6
activating transcription factor 6
chr2_-_241500447 0.15 ENST00000536462.1
ENST00000405002.1
ENST00000441168.1
ENST00000403283.1
ANKMY1
ankyrin repeat and MYND domain containing 1
chrX_+_148793714 0.15 ENST00000355220.5
MAGEA11
melanoma antigen family A, 11
chr22_-_23974506 0.14 ENST00000317749.5
C22orf43
chromosome 22 open reading frame 43
chr7_+_73106926 0.13 ENST00000453316.1
WBSCR22
Williams Beuren syndrome chromosome region 22
chrX_-_134049262 0.13 ENST00000370783.3
MOSPD1
motile sperm domain containing 1
chr22_+_31489344 0.13 ENST00000404574.1
SMTN
smoothelin
chr1_+_47264711 0.13 ENST00000371923.4
ENST00000271153.4
ENST00000371919.4
CYP4B1
cytochrome P450, family 4, subfamily B, polypeptide 1
chr11_-_82997420 0.12 ENST00000455220.2
ENST00000529689.1
CCDC90B
coiled-coil domain containing 90B
chr14_-_39417473 0.12 ENST00000553932.1
LINC00639
long intergenic non-protein coding RNA 639
chr2_+_217277466 0.12 ENST00000358207.5
ENST00000434435.1
SMARCAL1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
chr5_-_132166579 0.12 ENST00000378679.3
SHROOM1
shroom family member 1
chr8_+_37594103 0.12 ENST00000397228.2
ERLIN2
ER lipid raft associated 2
chr5_+_68462837 0.12 ENST00000256442.5
CCNB1
cyclin B1
chr7_+_134212312 0.12 ENST00000359579.4
AKR1B10
aldo-keto reductase family 1, member B10 (aldose reductase)
chr9_-_21217310 0.12 ENST00000380216.1
IFNA16
interferon, alpha 16
chr11_-_8615720 0.12 ENST00000358872.3
ENST00000454443.2
STK33
serine/threonine kinase 33
chr4_-_122791583 0.11 ENST00000506636.1
ENST00000264499.4
BBS7
Bardet-Biedl syndrome 7
chr1_-_71546690 0.11 ENST00000254821.6
ZRANB2
zinc finger, RAN-binding domain containing 2
chr2_+_79412357 0.11 ENST00000466387.1
CTNNA2
catenin (cadherin-associated protein), alpha 2
chr15_+_66161792 0.11 ENST00000564910.1
ENST00000261890.2
RAB11A
RAB11A, member RAS oncogene family
chr15_+_63188009 0.11 ENST00000557900.1
RP11-1069G10.2
RP11-1069G10.2
chr21_+_40752170 0.11 ENST00000333781.5
ENST00000541890.1
WRB
tryptophan rich basic protein
chr10_+_78078088 0.11 ENST00000496424.2
C10orf11
chromosome 10 open reading frame 11
chr6_-_15586238 0.11 ENST00000462989.2
DTNBP1
dystrobrevin binding protein 1
chr12_-_95467356 0.10 ENST00000393101.3
ENST00000333003.5
NR2C1
nuclear receptor subfamily 2, group C, member 1
chr10_+_102882536 0.10 ENST00000598040.1
HUG1
HUG1
chr5_+_140306478 0.10 ENST00000253807.2
PCDHAC1
protocadherin alpha subfamily C, 1
chr19_-_52034971 0.10 ENST00000346477.3
SIGLEC6
sialic acid binding Ig-like lectin 6
chr2_+_37458776 0.09 ENST00000002125.4
ENST00000336237.6
ENST00000431821.1
NDUFAF7
NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
chr15_+_66161802 0.09 ENST00000566233.1
ENST00000565075.1
ENST00000435304.2
RAB11A
RAB11A, member RAS oncogene family
chr1_-_10003372 0.09 ENST00000377223.1
ENST00000541052.1
ENST00000377213.1
LZIC
leucine zipper and CTNNBIP1 domain containing
chr19_-_16770915 0.09 ENST00000593459.1
ENST00000358726.6
ENST00000597711.1
ENST00000487416.2
CTC-429P9.4
SMIM7
Small integral membrane protein 7; Uncharacterized protein
small integral membrane protein 7
chr12_-_123187890 0.09 ENST00000328880.5
HCAR2
hydroxycarboxylic acid receptor 2
chr5_+_76248538 0.09 ENST00000274368.4
CRHBP
corticotropin releasing hormone binding protein
chr5_-_125930929 0.09 ENST00000553117.1
ENST00000447989.2
ENST00000409134.3
ALDH7A1
aldehyde dehydrogenase 7 family, member A1
chr1_+_10003486 0.08 ENST00000403197.1
ENST00000377205.1
NMNAT1
nicotinamide nucleotide adenylyltransferase 1
chr22_+_24115000 0.08 ENST00000215743.3
MMP11
matrix metallopeptidase 11 (stromelysin 3)
chr2_-_178257401 0.08 ENST00000464747.1
NFE2L2
nuclear factor, erythroid 2-like 2
chr15_+_66161871 0.08 ENST00000569896.1
RAB11A
RAB11A, member RAS oncogene family
chr12_-_14967095 0.08 ENST00000316048.2
SMCO3
single-pass membrane protein with coiled-coil domains 3
chr3_+_101504200 0.08 ENST00000422132.1
NXPE3
neurexophilin and PC-esterase domain family, member 3
chr2_-_32490859 0.07 ENST00000404025.2
NLRC4
NLR family, CARD domain containing 4
chr1_-_207143802 0.07 ENST00000324852.4
ENST00000400962.3
FCAMR
Fc receptor, IgA, IgM, high affinity
chr3_-_50360192 0.07 ENST00000442581.1
ENST00000447092.1
ENST00000357750.4
HYAL2
hyaluronoglucosaminidase 2
chr20_-_34330129 0.07 ENST00000397370.3
ENST00000528062.3
ENST00000407261.4
ENST00000374038.3
ENST00000361162.6
RBM39
RNA binding motif protein 39
chr4_-_76862117 0.07 ENST00000507956.1
ENST00000507187.2
ENST00000399497.3
ENST00000286733.4
NAAA
N-acylethanolamine acid amidase
chr9_+_112542591 0.07 ENST00000483909.1
ENST00000314527.4
ENST00000413420.1
ENST00000302798.7
ENST00000555236.1
ENST00000510514.5
PALM2
PALM2-AKAP2
AKAP2
paralemmin 2
PALM2-AKAP2 readthrough
A kinase (PRKA) anchor protein 2
chr8_+_37594185 0.07 ENST00000518586.1
ENST00000335171.6
ENST00000521644.1
ERLIN2
ER lipid raft associated 2
chr7_+_76090993 0.06 ENST00000425780.1
ENST00000456590.1
ENST00000451769.1
ENST00000324432.5
ENST00000307569.8
ENST00000457529.1
ENST00000446600.1
ENST00000413936.2
ENST00000423646.1
ENST00000438930.1
ENST00000430490.2
DTX2
deltex homolog 2 (Drosophila)
chr19_-_9903666 0.06 ENST00000592587.1
ZNF846
zinc finger protein 846
chr2_+_234580525 0.06 ENST00000609637.1
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr4_-_8430152 0.06 ENST00000514423.1
ENST00000503233.1
ACOX3
acyl-CoA oxidase 3, pristanoyl
chr4_-_70361615 0.06 ENST00000305107.6
UGT2B4
UDP glucuronosyltransferase 2 family, polypeptide B4
chr14_-_107083690 0.06 ENST00000455737.1
ENST00000390629.2
IGHV4-59
immunoglobulin heavy variable 4-59
chr15_+_73735490 0.06 ENST00000331090.6
ENST00000560581.1
C15orf60
chromosome 15 open reading frame 60
chr16_+_83841448 0.06 ENST00000433866.2
HSBP1
heat shock factor binding protein 1
chr7_-_144533074 0.05 ENST00000360057.3
ENST00000378099.3
TPK1
thiamin pyrophosphokinase 1
chr22_+_41763274 0.05 ENST00000406644.3
TEF
thyrotrophic embryonic factor
chr8_-_57906362 0.05 ENST00000262644.4
IMPAD1
inositol monophosphatase domain containing 1
chr13_+_53226963 0.05 ENST00000343788.6
ENST00000535397.1
ENST00000310528.8
SUGT1
SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)
chr22_-_42336209 0.05 ENST00000472374.2
CENPM
centromere protein M
chr6_+_3982909 0.05 ENST00000356722.3
C6ORF50
C6ORF50
chr15_-_41694640 0.05 ENST00000558719.1
ENST00000260361.4
ENST00000560978.1
NDUFAF1
NADH dehydrogenase (ubiquinone) complex I, assembly factor 1
chr2_+_234580499 0.05 ENST00000354728.4
UGT1A9
UDP glucuronosyltransferase 1 family, polypeptide A9
chr16_+_71560023 0.05 ENST00000572450.1
CHST4
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
chrY_+_3447082 0.04 ENST00000321217.4
ENST00000559055.2
TGIF2LY
TGFB-induced factor homeobox 2-like, Y-linked
chr2_-_32490801 0.04 ENST00000360906.5
ENST00000342905.6
NLRC4
NLR family, CARD domain containing 4
chr11_+_8704298 0.04 ENST00000531978.1
ENST00000524496.1
ENST00000532359.1
ENST00000530022.1
RPL27A
ribosomal protein L27a
chr4_-_70361579 0.04 ENST00000512583.1
UGT2B4
UDP glucuronosyltransferase 2 family, polypeptide B4
chr5_+_68462944 0.04 ENST00000506572.1
CCNB1
cyclin B1
chr5_+_68463043 0.04 ENST00000508407.1
ENST00000505500.1
CCNB1
cyclin B1
chr20_-_34542548 0.03 ENST00000305978.2
SCAND1
SCAN domain containing 1
chr19_-_52035044 0.03 ENST00000359982.4
ENST00000436458.1
ENST00000425629.3
ENST00000391797.3
ENST00000343300.4
SIGLEC6
sialic acid binding Ig-like lectin 6
chr9_-_132586378 0.03 ENST00000351698.4
TOR1A
torsin family 1, member A (torsin A)
chr21_-_34915147 0.03 ENST00000381831.3
ENST00000381839.3
GART
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
chr15_-_74284613 0.03 ENST00000316911.6
ENST00000564777.1
ENST00000566081.1
ENST00000316900.5
STOML1
stomatin (EPB72)-like 1
chr5_+_70220768 0.03 ENST00000351205.4
ENST00000503079.2
ENST00000380707.4
ENST00000514951.1
ENST00000506163.1
SMN1
survival of motor neuron 1, telomeric
chr6_+_101847105 0.02 ENST00000369137.3
ENST00000318991.6
GRIK2
glutamate receptor, ionotropic, kainate 2
chr19_+_7694623 0.02 ENST00000594797.1
ENST00000456958.3
ENST00000601406.1
PET100
PET100 homolog (S. cerevisiae)
chr10_-_53459319 0.02 ENST00000331173.4
CSTF2T
cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
chr2_-_37458749 0.02 ENST00000234170.5
CEBPZ
CCAAT/enhancer binding protein (C/EBP), zeta
chr15_-_51397473 0.02 ENST00000327536.5
TNFAIP8L3
tumor necrosis factor, alpha-induced protein 8-like 3
chr11_+_8704748 0.02 ENST00000526562.1
ENST00000525981.1
RPL27A
ribosomal protein L27a
chr11_-_77705687 0.02 ENST00000529807.1
ENST00000527522.1
ENST00000534064.1
INTS4
integrator complex subunit 4
chr15_+_36994210 0.02 ENST00000562489.1
C15orf41
chromosome 15 open reading frame 41
chr5_+_69345350 0.01 ENST00000380741.4
ENST00000380743.4
ENST00000511812.1
ENST00000380742.4
SMN2
survival of motor neuron 2, centromeric
chr7_-_138347897 0.01 ENST00000288513.5
SVOPL
SVOP-like
chr15_+_58724184 0.01 ENST00000433326.2
LIPC
lipase, hepatic
chr19_-_5680231 0.01 ENST00000587950.1
C19orf70
chromosome 19 open reading frame 70
chr17_-_7145475 0.01 ENST00000571129.1
ENST00000571253.1
ENST00000573928.1
GABARAP
GABA(A) receptor-associated protein
chr2_-_114300213 0.01 ENST00000446595.1
ENST00000416105.1
ENST00000450636.1
ENST00000416758.1
RP11-395L14.4
RP11-395L14.4
chr12_-_50419177 0.01 ENST00000454520.2
ENST00000546595.1
ENST00000548824.1
ENST00000549777.1
ENST00000546723.1
ENST00000427314.2
ENST00000552157.1
ENST00000552310.1
ENST00000548644.1
ENST00000312377.5
ENST00000546786.1
ENST00000550149.1
ENST00000546764.1
ENST00000552004.1
ENST00000548320.1
ENST00000547905.1
ENST00000550651.1
ENST00000551145.1
ENST00000434422.1
ENST00000552921.1
RACGAP1
Rac GTPase activating protein 1
chr10_+_95848824 0.01 ENST00000371385.3
ENST00000371375.1
PLCE1
phospholipase C, epsilon 1
chr10_+_101088836 0.01 ENST00000356713.4
CNNM1
cyclin M1
chr19_-_5680202 0.01 ENST00000590389.1
C19orf70
chromosome 19 open reading frame 70
chr5_+_140306302 0.01 ENST00000409700.3
PCDHAC1
protocadherin alpha subfamily C, 1
chr2_-_148779106 0.01 ENST00000416719.1
ENST00000264169.2
ORC4
origin recognition complex, subunit 4
chr19_+_19303008 0.01 ENST00000353145.1
ENST00000421262.3
ENST00000303088.4
ENST00000456252.3
ENST00000593273.1
RFXANK
regulatory factor X-associated ankyrin-containing protein

Network of associatons between targets according to the STRING database.

First level regulatory network of OSR1_OSR2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0042668 trochlear nerve development(GO:0021558) auditory receptor cell fate determination(GO:0042668) negative regulation of auditory receptor cell differentiation(GO:0045608) regulation of timing of neuron differentiation(GO:0060164) negative regulation of pro-B cell differentiation(GO:2000974)
0.8 2.4 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.3 2.1 GO:0071461 cellular response to redox state(GO:0071461)
0.2 4.1 GO:0046069 cGMP catabolic process(GO:0046069)
0.2 1.7 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.2 0.9 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.1 0.4 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.1 4.2 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 1.2 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.1 0.8 GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
0.1 0.7 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 0.5 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 0.3 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.1 0.2 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
0.1 0.6 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.1 0.4 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 0.2 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.1 0.2 GO:2000547 regulation of dendritic cell dendrite assembly(GO:2000547)
0.1 0.4 GO:0070885 positive regulation of sodium:proton antiporter activity(GO:0032417) negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0 2.2 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.3 GO:0010796 regulation of multivesicular body size(GO:0010796)
0.0 1.5 GO:0040036 regulation of fibroblast growth factor receptor signaling pathway(GO:0040036)
0.0 0.2 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.0 0.2 GO:0030820 regulation of cyclic nucleotide catabolic process(GO:0030805) regulation of cAMP catabolic process(GO:0030820) regulation of purine nucleotide catabolic process(GO:0033121) regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.4 GO:0060523 prostate epithelial cord elongation(GO:0060523) epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.0 0.9 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.1 GO:0006711 estrogen catabolic process(GO:0006711)
0.0 0.3 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.2 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.1 GO:0071314 cellular response to cocaine(GO:0071314)
0.0 0.0 GO:1902805 positive regulation of synaptic vesicle endocytosis(GO:1900244) positive regulation of synaptic vesicle transport(GO:1902805) positive regulation of synaptic vesicle recycling(GO:1903423)
0.0 0.1 GO:0031456 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.1 GO:0016095 polyprenol catabolic process(GO:0016095)
0.0 0.3 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.2 GO:0018879 biphenyl metabolic process(GO:0018879)
0.0 1.1 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.3 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.5 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.3 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:0019087 transformation of host cell by virus(GO:0019087)
0.0 0.1 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.0 0.1 GO:0046223 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 0.1 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.7 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 0.1 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.1 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.1 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.0 1.2 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 2.5 GO:0031424 keratinization(GO:0031424)
0.0 0.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.2 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.1 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.5 GO:0006379 mRNA cleavage(GO:0006379)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.1 0.2 GO:0042022 interleukin-12 receptor complex(GO:0042022)
0.1 0.3 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 1.0 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.3 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 0.2 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.0 0.4 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.8 GO:0009925 basal plasma membrane(GO:0009925)
0.0 4.2 GO:0030018 Z disc(GO:0030018)
0.0 2.5 GO:0005882 intermediate filament(GO:0005882)
0.0 1.6 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.2 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.1 GO:0043196 varicosity(GO:0043196)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0016992 lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283)
0.6 4.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2 1.5 GO:0097108 hedgehog family protein binding(GO:0097108)
0.2 2.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2 0.5 GO:0016730 ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.1 4.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.4 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 0.8 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 1.7 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 2.2 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.1 0.3 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1 1.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 0.2 GO:0016517 interleukin-12 receptor activity(GO:0016517)
0.0 0.4 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.3 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.1 GO:0047718 indanol dehydrogenase activity(GO:0047718)
0.0 0.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.2 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 1.1 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292) hyaluronoglucuronidase activity(GO:0033906)
0.0 0.1 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 2.8 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.5 GO:0005521 lamin binding(GO:0005521)
0.0 0.6 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.3 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.0 0.7 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.2 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.7 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.7 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.1 GO:0052832 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.1 GO:0036310 annealing helicase activity(GO:0036310)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.7 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.8 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.3 PID FOXM1 PATHWAY FOXM1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.1 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 2.7 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.5 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 1.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.2 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.9 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.7 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.6 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism