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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for OTP_PHOX2B_LHX1_LMX1A_LHX5_HOXC4

Z-value: 0.52

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Transcription factors associated with OTP_PHOX2B_LHX1_LMX1A_LHX5_HOXC4

Gene Symbol Gene ID Gene Info
ENSG00000171540.6 orthopedia homeobox
ENSG00000109132.5 paired like homeobox 2B
ENSG00000132130.7 LIM homeobox 1
ENSG00000162761.10 LIM homeobox transcription factor 1 alpha
ENSG00000089116.3 LIM homeobox 5
ENSG00000198353.6 homeobox C4
ENSG00000273266.1 homeobox C4

Activity-expression correlation:

Activity profile of OTP_PHOX2B_LHX1_LMX1A_LHX5_HOXC4 motif

Sorted Z-values of OTP_PHOX2B_LHX1_LMX1A_LHX5_HOXC4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_141747950 1.72 ENST00000497579.1
transcription factor Dp-2 (E2F dimerization partner 2)
chr12_+_26348582 1.43 ENST00000535504.1
sarcospan
chr1_+_117544366 1.08 ENST00000256652.4
ENST00000369470.1
CD101 molecule
chr11_-_121986923 1.01 ENST00000560104.1
BH3-like motif containing, cell death inducer
chr17_+_1674982 0.79 ENST00000572048.1
ENST00000573763.1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr3_-_141719195 0.74 ENST00000397991.4
transcription factor Dp-2 (E2F dimerization partner 2)
chr1_-_160924589 0.70 ENST00000368029.3
intelectin 2
chr14_+_31046959 0.69 ENST00000547532.1
ENST00000555429.1
G2/M-phase specific E3 ubiquitin protein ligase
chr20_-_33735070 0.68 ENST00000374491.3
ENST00000542871.1
ENST00000374492.3
ER degradation enhancer, mannosidase alpha-like 2
chr16_-_30122717 0.59 ENST00000566613.1
glycerophosphodiester phosphodiesterase domain containing 3
chr10_-_118928543 0.57 ENST00000419373.2
RP11-501J20.2
chr19_+_50016411 0.51 ENST00000426395.3
ENST00000600273.1
ENST00000599988.1
Fc fragment of IgG, receptor, transporter, alpha
chr2_-_241497374 0.50 ENST00000373318.2
ENST00000406958.1
ENST00000391987.1
ENST00000373320.4
ankyrin repeat and MYND domain containing 1
chr11_-_63376013 0.49 ENST00000540943.1
phospholipase A2, group XVI
chr19_+_50016610 0.44 ENST00000596975.1
Fc fragment of IgG, receptor, transporter, alpha
chr1_+_225600404 0.44 ENST00000366845.2
AC092811.1
chr1_-_92371839 0.42 ENST00000370399.2
transforming growth factor, beta receptor III
chr4_+_169418255 0.42 ENST00000505667.1
ENST00000511948.1
palladin, cytoskeletal associated protein
chr15_-_20193370 0.41 ENST00000558565.2
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr3_-_149293990 0.39 ENST00000472417.1
WW domain containing transcription regulator 1
chr5_+_66300446 0.38 ENST00000261569.7
microtubule associated serine/threonine kinase family member 4
chr1_-_201140673 0.37 ENST00000367333.2
transmembrane protein 9
chr20_+_15177480 0.35 ENST00000402914.1
MACRO domain containing 2
chrX_-_18690210 0.35 ENST00000379984.3
retinoschisin 1
chr11_-_5323226 0.35 ENST00000380224.1
olfactory receptor, family 51, subfamily B, member 4
chr7_+_133812052 0.35 ENST00000285928.2
leucine-rich repeats and guanylate kinase domain containing
chr1_-_190446759 0.34 ENST00000367462.3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr4_+_169418195 0.34 ENST00000261509.6
ENST00000335742.7
palladin, cytoskeletal associated protein
chr12_+_8309630 0.33 ENST00000396570.3
zinc finger protein 705A
chr2_+_90211643 0.32 ENST00000390277.2
immunoglobulin kappa variable 3D-11
chr2_+_234826016 0.31 ENST00000324695.4
ENST00000433712.2
transient receptor potential cation channel, subfamily M, member 8
chr11_-_128894053 0.31 ENST00000392657.3
Rho GTPase activating protein 32
chr3_-_64211112 0.31 ENST00000295902.6
prickle homolog 2 (Drosophila)
chr6_+_130339710 0.29 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
l(3)mbt-like 3 (Drosophila)
chr12_-_10022735 0.28 ENST00000228438.2
C-type lectin domain family 2, member B
chr11_+_114168085 0.27 ENST00000541754.1
nicotinamide N-methyltransferase
chr4_+_76481258 0.26 ENST00000311623.4
ENST00000435974.2
chromosome 4 open reading frame 26
chr6_-_32157947 0.25 ENST00000375050.4
pre-B-cell leukemia homeobox 2
chr2_+_90077680 0.24 ENST00000390270.2
immunoglobulin kappa variable 3D-20
chr12_-_46121554 0.24 ENST00000609803.1
long intergenic non-protein coding RNA 938
chr13_+_24144796 0.24 ENST00000403372.2
tumor necrosis factor receptor superfamily, member 19
chr15_+_58702742 0.23 ENST00000356113.6
ENST00000414170.3
lipase, hepatic
chr1_+_15668240 0.23 ENST00000444385.1
forkhead-associated (FHA) phosphopeptide binding domain 1
chr2_-_89327228 0.23 ENST00000483158.1
immunoglobulin kappa variable 3-11
chr12_-_9913489 0.22 ENST00000228434.3
ENST00000536709.1
CD69 molecule
chr16_+_15489603 0.22 ENST00000568766.1
ENST00000287594.7
Uncharacterized protein
MPV17 mitochondrial membrane protein-like
chr3_-_20053741 0.21 ENST00000389050.4
protein phosphatase 2C-like domain containing 1
chr15_-_75748115 0.21 ENST00000360439.4
SIN3 transcription regulator family member A
chr8_-_86253888 0.21 ENST00000522389.1
ENST00000432364.2
ENST00000517618.1
carbonic anhydrase I
chr19_-_51920952 0.20 ENST00000356298.5
ENST00000339313.5
ENST00000529627.1
ENST00000439889.2
ENST00000353836.5
ENST00000432469.2
sialic acid binding Ig-like lectin 10
chr7_-_37024665 0.20 ENST00000396040.2
engulfment and cell motility 1
chr19_+_49199209 0.20 ENST00000522966.1
ENST00000425340.2
ENST00000391876.4
fucosyltransferase 2 (secretor status included)
chr3_+_186353756 0.20 ENST00000431018.1
ENST00000450521.1
ENST00000539949.1
fetuin B
chr9_+_95997205 0.20 ENST00000411624.1
WNK lysine deficient protein kinase 2
chr17_+_48823896 0.19 ENST00000511974.1
LUC7-like 3 (S. cerevisiae)
chr2_-_74618964 0.18 ENST00000417090.1
ENST00000409868.1
dynactin 1
chr7_+_129932974 0.18 ENST00000445470.2
ENST00000222482.4
ENST00000492072.1
ENST00000473956.1
ENST00000493259.1
ENST00000486598.1
carboxypeptidase A4
chr12_-_52779433 0.18 ENST00000257951.3
keratin 84
chr2_-_43266680 0.18 ENST00000425212.1
ENST00000422351.1
ENST00000449766.1
AC016735.2
chr7_-_143599207 0.17 ENST00000355951.2
ENST00000479870.1
ENST00000478172.1
family with sequence similarity 115, member A
chr5_+_140762268 0.17 ENST00000518325.1
protocadherin gamma subfamily A, 7
chr12_-_54653313 0.17 ENST00000550411.1
ENST00000439541.2
chromobox homolog 5
chr12_-_22063787 0.17 ENST00000544039.1
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr9_+_71986182 0.17 ENST00000303068.7
family with sequence similarity 189, member A2
chr7_+_115862858 0.17 ENST00000393481.2
testis derived transcript (3 LIM domains)
chr1_-_92952433 0.17 ENST00000294702.5
growth factor independent 1 transcription repressor
chr2_+_90273679 0.15 ENST00000423080.2
immunoglobulin kappa variable 3D-7
chr11_-_327537 0.15 ENST00000602735.1
interferon induced transmembrane protein 3
chr2_-_89385283 0.14 ENST00000390252.2
immunoglobulin kappa variable 3-15
chr7_+_102553430 0.14 ENST00000339431.4
ENST00000249377.4
leucine rich repeat containing 17
chr5_+_95066823 0.14 ENST00000506817.1
ENST00000379982.3
Rho-related BTB domain containing 3
chr20_-_18477862 0.14 ENST00000337227.4
retinoblastoma binding protein 9
chr11_-_102576537 0.14 ENST00000260229.4
matrix metallopeptidase 27
chr6_+_47624172 0.13 ENST00000507065.1
ENST00000296862.1
G protein-coupled receptor 111
chr19_-_14945933 0.13 ENST00000322301.3
olfactory receptor, family 7, subfamily A, member 5
chrX_-_21676442 0.13 ENST00000379499.2
kelch-like family member 34
chr6_+_47749718 0.13 ENST00000489301.2
ENST00000371211.2
ENST00000393699.2
opsin 5
chr7_+_73868120 0.13 ENST00000265755.3
GTF2I repeat domain containing 1
chr9_-_99540328 0.12 ENST00000223428.4
ENST00000375231.1
ENST00000374641.3
zinc finger protein 510
chr2_-_74619152 0.12 ENST00000440727.1
ENST00000409240.1
dynactin 1
chr16_-_66584059 0.12 ENST00000417693.3
ENST00000544898.1
ENST00000569718.1
ENST00000527284.1
ENST00000299697.7
ENST00000451102.2
thymidine kinase 2, mitochondrial
chr2_-_241497390 0.12 ENST00000272972.3
ENST00000401804.1
ENST00000361678.4
ENST00000405523.3
ankyrin repeat and MYND domain containing 1
chr2_-_191115229 0.12 ENST00000409820.2
ENST00000410045.1
3-hydroxyisobutyryl-CoA hydrolase
chr7_+_73868439 0.12 ENST00000424337.2
GTF2I repeat domain containing 1
chr9_+_125133315 0.12 ENST00000223423.4
ENST00000362012.2
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr2_-_231860596 0.12 ENST00000441063.1
ENST00000434094.1
ENST00000418330.1
ENST00000457803.1
ENST00000414876.1
ENST00000446741.1
ENST00000426904.1
SPATA3 antisense RNA 1 (head to head)
chr12_+_20963632 0.12 ENST00000540853.1
ENST00000261196.2
solute carrier organic anion transporter family, member 1B3
chrX_-_100872911 0.12 ENST00000361910.4
ENST00000539247.1
ENST00000538627.1
armadillo repeat containing, X-linked 6
chr12_-_25348007 0.11 ENST00000354189.5
ENST00000545133.1
ENST00000554347.1
ENST00000395987.3
ENST00000320267.9
ENST00000395990.2
ENST00000537577.1
cancer susceptibility candidate 1
chr14_+_22670455 0.11 ENST00000390460.1
T cell receptor alpha variable 26-2
chr21_+_17909594 0.11 ENST00000441820.1
ENST00000602280.1
long intergenic non-protein coding RNA 478
chr20_-_50419055 0.11 ENST00000217086.4
spalt-like transcription factor 4
chr4_+_155484155 0.11 ENST00000509493.1
fibrinogen beta chain
chr2_-_40680578 0.10 ENST00000455476.1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr10_+_101542462 0.10 ENST00000370449.4
ENST00000370434.1
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr12_+_59989918 0.10 ENST00000547379.1
ENST00000549465.1
solute carrier family 16 (monocarboxylate transporter), member 7
chr17_+_20978854 0.10 ENST00000456235.1
AC087393.1
chr9_+_34652164 0.10 ENST00000441545.2
ENST00000553620.1
interleukin 11 receptor, alpha
chr12_-_10282742 0.10 ENST00000298523.5
ENST00000396484.2
ENST00000310002.4
C-type lectin domain family 7, member A
chrX_+_77166172 0.10 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATPase, Cu++ transporting, alpha polypeptide
chr7_-_111032971 0.10 ENST00000450877.1
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr16_+_31271274 0.10 ENST00000287497.8
ENST00000544665.3
integrin, alpha M (complement component 3 receptor 3 subunit)
chr20_-_56265680 0.10 ENST00000414037.1
prostate transmembrane protein, androgen induced 1
chr12_-_10282836 0.10 ENST00000304084.8
ENST00000353231.5
ENST00000525605.1
C-type lectin domain family 7, member A
chr3_+_44840679 0.10 ENST00000425755.1
kinesin family member 15
chr1_+_180601139 0.10 ENST00000367590.4
ENST00000367589.3
xenotropic and polytropic retrovirus receptor 1
chr7_+_150020329 0.10 ENST00000323078.7
leucine rich repeat containing 61
chr14_+_102276192 0.09 ENST00000557714.1
protein phosphatase 2, regulatory subunit B', gamma
chr4_+_108745711 0.09 ENST00000394684.4
sphingomyelin synthase 2
chr15_-_37393406 0.09 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
Meis homeobox 2
chr12_+_104337515 0.09 ENST00000550595.1
heat shock protein 90kDa beta (Grp94), member 1
chr18_-_52989217 0.08 ENST00000570287.2
transcription factor 4
chr10_-_95241951 0.08 ENST00000358334.5
ENST00000359263.4
ENST00000371488.3
myoferlin
chr17_-_46688334 0.08 ENST00000239165.7
homeobox B7
chr4_+_155484103 0.08 ENST00000302068.4
fibrinogen beta chain
chr17_-_38821373 0.08 ENST00000394052.3
keratin 222
chr19_-_44388116 0.08 ENST00000587539.1
zinc finger protein 404
chr10_-_28571015 0.08 ENST00000375719.3
ENST00000375732.1
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chrX_+_55744228 0.08 ENST00000262850.7
Ras-related GTP binding B
chr1_+_205682497 0.08 ENST00000598338.1
AC119673.1
chr10_-_95242044 0.08 ENST00000371501.4
ENST00000371502.4
ENST00000371489.1
myoferlin
chr16_-_28937027 0.08 ENST00000358201.4
rabaptin, RAB GTPase binding effector protein 2
chr17_+_74463650 0.08 ENST00000392492.3
aralkylamine N-acetyltransferase
chr5_+_175288631 0.08 ENST00000509837.1
complexin 2
chrX_+_55744166 0.08 ENST00000374941.4
ENST00000414239.1
Ras-related GTP binding B
chr9_+_90112767 0.08 ENST00000408954.3
death-associated protein kinase 1
chr18_-_53177984 0.08 ENST00000543082.1
transcription factor 4
chr2_+_202047596 0.08 ENST00000286186.6
ENST00000360132.3
caspase 10, apoptosis-related cysteine peptidase
chrX_+_153533275 0.08 ENST00000426989.1
ENST00000426203.1
ENST00000369912.2
transketolase-like 1
chr6_-_116833500 0.07 ENST00000356128.4
trafficking protein particle complex 3-like
chr11_+_118398178 0.07 ENST00000302783.4
ENST00000539546.1
tetratricopeptide repeat domain 36
chr7_+_150020363 0.07 ENST00000359623.4
ENST00000493307.1
leucine rich repeat containing 61
chr2_-_163008903 0.07 ENST00000418842.2
ENST00000375497.3
glucagon
chr3_-_164796269 0.07 ENST00000264382.3
sucrase-isomaltase (alpha-glucosidase)
chr9_+_90112590 0.07 ENST00000472284.1
death-associated protein kinase 1
chr19_-_58326267 0.07 ENST00000391701.1
zinc finger protein 552
chr21_-_27423339 0.07 ENST00000415997.1
amyloid beta (A4) precursor protein
chr14_-_45252031 0.07 ENST00000556405.1
RP11-398E10.1
chr2_+_109237717 0.07 ENST00000409441.1
LIM and senescent cell antigen-like domains 1
chr6_-_155776966 0.07 ENST00000159060.2
NADPH oxidase 3
chr17_-_9694614 0.07 ENST00000330255.5
ENST00000571134.1
dehydrogenase/reductase (SDR family) member 7C
chr6_+_3259148 0.07 ENST00000419065.2
ENST00000473000.2
ENST00000451246.2
ENST00000454610.2
proteasome (prosome, macropain) assembly chaperone 4
chr2_+_105050794 0.07 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
long intergenic non-protein coding RNA 1102
chr15_+_84115868 0.07 ENST00000427482.2
SH3-domain GRB2-like 3
chr7_+_73868220 0.07 ENST00000455841.2
GTF2I repeat domain containing 1
chrX_+_1710484 0.07 ENST00000313871.3
ENST00000381261.3
A kinase (PRKA) anchor protein 17A
chr4_-_185275104 0.07 ENST00000317596.3
RP11-290F5.2
chrX_+_134975753 0.06 ENST00000535938.1
sarcoma antigen 1
chr12_-_10151773 0.06 ENST00000298527.6
ENST00000348658.4
C-type lectin domain family 1, member B
chrX_+_134975858 0.06 ENST00000537770.1
sarcoma antigen 1
chr14_+_50234309 0.06 ENST00000298307.5
kelch domain containing 2
chr17_+_67498538 0.06 ENST00000589647.1
mitogen-activated protein kinase kinase 6
chr6_-_144385698 0.06 ENST00000444202.1
ENST00000437412.1
pleiomorphic adenoma gene-like 1
chr6_+_26087509 0.06 ENST00000397022.3
ENST00000353147.5
ENST00000352392.4
ENST00000349999.4
ENST00000317896.7
ENST00000357618.5
ENST00000470149.1
ENST00000336625.8
ENST00000461397.1
ENST00000488199.1
hemochromatosis
chr5_-_176889381 0.06 ENST00000393563.4
ENST00000512501.1
drebrin 1
chr12_+_26348246 0.06 ENST00000422622.2
sarcospan
chr20_-_50418947 0.06 ENST00000371539.3
spalt-like transcription factor 4
chr1_-_211307404 0.06 ENST00000367007.4
potassium voltage-gated channel, subfamily H (eag-related), member 1
chr17_+_66511540 0.06 ENST00000588188.2
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr12_-_74686314 0.06 ENST00000551210.1
ENST00000515416.2
ENST00000549905.1
RP11-81H3.2
chr6_-_10415470 0.06 ENST00000379604.2
ENST00000379613.3
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chrX_+_36254051 0.06 ENST00000378657.4
chromosome X open reading frame 30
chr7_-_102283238 0.06 ENST00000340457.8
uroplakin 3B-like
chr3_+_141457105 0.06 ENST00000480908.1
ENST00000393000.3
ring finger protein 7
chr20_-_50418972 0.05 ENST00000395997.3
spalt-like transcription factor 4
chr10_-_75415825 0.05 ENST00000394810.2
synaptopodin 2-like
chr12_-_7655329 0.05 ENST00000541972.1
CD163 molecule
chr18_+_61254534 0.05 ENST00000269489.5
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr12_+_26348429 0.05 ENST00000242729.2
sarcospan
chr17_-_42992856 0.05 ENST00000588316.1
ENST00000435360.2
ENST00000586793.1
ENST00000588735.1
ENST00000588037.1
ENST00000592320.1
ENST00000253408.5
glial fibrillary acidic protein
chr3_+_141457030 0.05 ENST00000273480.3
ring finger protein 7
chr7_-_140482926 0.05 ENST00000496384.2
v-raf murine sarcoma viral oncogene homolog B
chr10_+_94451574 0.05 ENST00000492654.2
hematopoietically expressed homeobox
chr3_-_114477787 0.05 ENST00000464560.1
zinc finger and BTB domain containing 20
chr5_+_140593509 0.05 ENST00000341948.4
protocadherin beta 13
chr4_+_158493642 0.05 ENST00000507108.1
ENST00000455598.1
ENST00000509450.1
RP11-364P22.1
chr5_-_125930929 0.05 ENST00000553117.1
ENST00000447989.2
ENST00000409134.3
aldehyde dehydrogenase 7 family, member A1
chr2_-_27886460 0.05 ENST00000404798.2
ENST00000405491.1
ENST00000464789.2
ENST00000406540.1
suppressor of Ty 7 (S. cerevisiae)-like
chr9_-_116065551 0.05 ENST00000297894.5
ring finger protein 183
chr9_-_21202204 0.05 ENST00000239347.3
interferon, alpha 7
chr2_-_8977714 0.05 ENST00000319688.5
ENST00000489024.1
ENST00000256707.3
ENST00000427284.1
ENST00000418530.1
ENST00000473731.1
kinase D-interacting substrate, 220kDa
chrX_+_36053908 0.05 ENST00000378660.2
calponin homology domain containing 2
chr22_+_40297105 0.05 ENST00000540310.1
GRB2-related adaptor protein 2
chr12_-_10282681 0.05 ENST00000533022.1
C-type lectin domain family 7, member A
chr2_+_166095898 0.05 ENST00000424833.1
ENST00000375437.2
ENST00000357398.3
sodium channel, voltage-gated, type II, alpha subunit
chr19_+_29456034 0.05 ENST00000589921.1
long intergenic non-protein coding RNA 906
chr6_+_125304502 0.05 ENST00000519799.1
ENST00000368414.2
ENST00000359704.2
ring finger protein 217
chr3_-_114477962 0.05 ENST00000471418.1
zinc finger and BTB domain containing 20
chr3_+_20081515 0.05 ENST00000263754.4
K(lysine) acetyltransferase 2B
chr15_+_54901540 0.04 ENST00000539562.2
unc-13 homolog C (C. elegans)
chr20_+_22034809 0.04 ENST00000449427.1
RP11-125P18.1
chr13_-_36050819 0.04 ENST00000379919.4
mab-21-like 1 (C. elegans)
chr18_-_52989525 0.04 ENST00000457482.3
transcription factor 4
chr10_-_50396425 0.04 ENST00000374148.1
chromosome 10 open reading frame 128
chr4_-_177116772 0.04 ENST00000280191.2
spermatogenesis associated 4
chr7_-_87342564 0.04 ENST00000265724.3
ENST00000416177.1
ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr3_+_138340049 0.04 ENST00000464668.1
Fas apoptotic inhibitory molecule
chr13_-_70682590 0.04 ENST00000377844.4
kelch-like family member 1
chr3_-_149095652 0.04 ENST00000305366.3
transmembrane 4 L six family member 1
chr5_+_140220769 0.04 ENST00000531613.1
ENST00000378123.3
protocadherin alpha 8

Network of associatons between targets according to the STRING database.

First level regulatory network of OTP_PHOX2B_LHX1_LMX1A_LHX5_HOXC4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0036509 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.2 0.9 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.1 1.0 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.1 0.4 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.1 0.3 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 0.3 GO:0050955 thermoception(GO:0050955)
0.1 2.6 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.2 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.1 0.2 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.1 0.4 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.5 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.3 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.1 GO:0046125 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0 0.1 GO:0016999 antibiotic metabolic process(GO:0016999) detoxification of mercury ion(GO:0050787)
0.0 0.1 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.8 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 0.1 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.4 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0 0.1 GO:0034761 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.0 0.1 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.1 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.2 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.1 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.1 GO:0061010 negative regulation of transcription by transcription factor localization(GO:0010621) gall bladder development(GO:0061010)
0.0 0.4 GO:0009642 response to light intensity(GO:0009642)
0.0 0.0 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.2 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.2 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:0003409 optic cup structural organization(GO:0003409)
0.0 0.1 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.1 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 1.1 GO:0002763 positive regulation of myeloid leukocyte differentiation(GO:0002763)
0.0 0.1 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.0 0.2 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.2 GO:0035878 nail development(GO:0035878)
0.0 0.2 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.1 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.8 GO:0043203 axon hillock(GO:0043203)
0.0 0.3 GO:0002177 manchette(GO:0002177)
0.0 1.5 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.1 GO:0005873 plus-end kinesin complex(GO:0005873)
0.0 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.2 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.3 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.7 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.0 GO:0000125 PCAF complex(GO:0000125)
0.0 0.1 GO:0030914 STAGA complex(GO:0030914)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 2.3 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.1 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.8 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 0.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0019770 IgG receptor activity(GO:0019770)
0.2 1.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1 0.5 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 0.3 GO:0008112 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.1 0.7 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0004797 thymidine kinase activity(GO:0004797)
0.0 0.2 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.4 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.1 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.2 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.1 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.1 GO:0004802 transketolase activity(GO:0004802)
0.0 0.6 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.2 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.7 PID E2F PATHWAY E2F transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.5 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo