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Inflammatory response time course, HUVEC (Wada et al., 2009)
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Results for OVOL1
Z-value: 0.29
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Transcription factors associated with OVOL1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
OVOL1
|
ENSG00000172818.5 | ovo like transcriptional repressor 1 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| OVOL1 | hg19_v2_chr11_+_65554493_65554546 | 0.20 | 3.4e-01 | Click! |
Activity profile of OVOL1 motif
Sorted Z-values of OVOL1 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chrX_-_117107680 | 0.84 |
ENST00000447671.2
ENST00000262820.3 |
KLHL13
|
kelch-like family member 13 |
| chrX_-_117107542 | 0.78 |
ENST00000371878.1
|
KLHL13
|
kelch-like family member 13 |
| chr6_-_84419101 | 0.74 |
ENST00000520302.1
ENST00000520213.1 ENST00000439399.2 ENST00000428679.2 ENST00000437520.1 |
SNAP91
|
synaptosomal-associated protein, 91kDa |
| chr3_-_165555200 | 0.48 |
ENST00000479451.1
ENST00000540653.1 ENST00000488954.1 ENST00000264381.3 |
BCHE
|
butyrylcholinesterase |
| chr2_-_183387430 | 0.41 |
ENST00000410103.1
|
PDE1A
|
phosphodiesterase 1A, calmodulin-dependent |
| chr10_-_21786179 | 0.34 |
ENST00000377113.5
|
CASC10
|
cancer susceptibility candidate 10 |
| chr16_-_67260691 | 0.30 |
ENST00000447579.1
ENST00000393992.1 ENST00000424285.1 |
LRRC29
|
leucine rich repeat containing 29 |
| chr14_+_29241910 | 0.26 |
ENST00000399387.4
ENST00000552957.1 ENST00000548213.1 |
C14orf23
|
chromosome 14 open reading frame 23 |
| chr2_-_183387064 | 0.25 |
ENST00000536095.1
ENST00000331935.6 ENST00000358139.2 ENST00000456212.1 |
PDE1A
|
phosphodiesterase 1A, calmodulin-dependent |
| chr7_-_148581360 | 0.23 |
ENST00000320356.2
ENST00000541220.1 ENST00000483967.1 ENST00000536783.1 |
EZH2
|
enhancer of zeste homolog 2 (Drosophila) |
| chr15_-_64385981 | 0.20 |
ENST00000557835.1
ENST00000380290.3 ENST00000559950.1 |
FAM96A
|
family with sequence similarity 96, member A |
| chr3_-_149093499 | 0.19 |
ENST00000472441.1
|
TM4SF1
|
transmembrane 4 L six family member 1 |
| chr15_-_64386120 | 0.18 |
ENST00000300030.3
|
FAM96A
|
family with sequence similarity 96, member A |
| chr4_+_76481258 | 0.18 |
ENST00000311623.4
ENST00000435974.2 |
C4orf26
|
chromosome 4 open reading frame 26 |
| chr15_+_75335604 | 0.15 |
ENST00000563393.1
|
PPCDC
|
phosphopantothenoylcysteine decarboxylase |
| chr16_-_67260901 | 0.15 |
ENST00000341546.3
ENST00000409509.1 ENST00000433915.1 ENST00000454102.2 |
LRRC29
AC040160.1
|
leucine rich repeat containing 29 Uncharacterized protein; cDNA FLJ57407, weakly similar to Mus musculus leucine rich repeat containing 29 (Lrrc29), mRNA |
| chr2_-_183387283 | 0.11 |
ENST00000435564.1
|
PDE1A
|
phosphodiesterase 1A, calmodulin-dependent |
| chr7_-_38389573 | 0.10 |
ENST00000390344.2
|
TRGV5
|
T cell receptor gamma variable 5 |
| chr19_+_6772710 | 0.09 |
ENST00000304076.2
ENST00000602142.1 ENST00000596764.1 |
VAV1
|
vav 1 guanine nucleotide exchange factor |
| chr20_+_54823788 | 0.08 |
ENST00000243911.2
|
MC3R
|
melanocortin 3 receptor |
| chr17_-_7145475 | 0.05 |
ENST00000571129.1
ENST00000571253.1 ENST00000573928.1 |
GABARAP
|
GABA(A) receptor-associated protein |
| chr5_+_140739537 | 0.05 |
ENST00000522605.1
|
PCDHGB2
|
protocadherin gamma subfamily B, 2 |
| chr5_+_140261703 | 0.04 |
ENST00000409494.1
ENST00000289272.2 |
PCDHA13
|
protocadherin alpha 13 |
| chr4_-_68620053 | 0.04 |
ENST00000420975.2
ENST00000226413.4 |
GNRHR
|
gonadotropin-releasing hormone receptor |
Network of associatons between targets according to the STRING database.
First level regulatory network of OVOL1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 0.5 | GO:0014016 | neuroblast differentiation(GO:0014016) |
| 0.1 | 0.2 | GO:0036333 | hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772) |
| 0.0 | 0.8 | GO:0046069 | cGMP catabolic process(GO:0046069) |
| 0.0 | 0.7 | GO:2000369 | regulation of clathrin-mediated endocytosis(GO:2000369) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.5 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.0 | 1.6 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 0.2 | GO:0045120 | pronucleus(GO:0045120) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.5 | GO:0003990 | acetylcholinesterase activity(GO:0003990) |
| 0.1 | 0.8 | GO:0048101 | calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
| 0.0 | 0.2 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
| 0.0 | 0.7 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.0 | 0.1 | GO:0004980 | melanocyte-stimulating hormone receptor activity(GO:0004980) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.6 | PID AURORA B PATHWAY | Aurora B signaling |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.5 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.0 | 0.8 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |