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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for PAX3

Z-value: 0.66

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Transcription factors associated with PAX3

Gene Symbol Gene ID Gene Info
PAX3
ENSG00000135903.14 paired box 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PAX3hg19_v2_chr2_-_223163465_2231637300.038.7e-01Click!

Activity profile of PAX3 motif

Sorted Z-values of PAX3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_101185290 3.91 ENST00000370119.4
ENST00000347652.2
ENST00000294728.2
ENST00000370115.1
VCAM1
vascular cell adhesion molecule 1
chr2_+_152214098 3.50 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr10_+_91087651 2.27 ENST00000371818.4
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr15_-_80263506 2.07 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr6_+_14117872 1.51 ENST00000379153.3
CD83
CD83 molecule
chr10_-_24770632 1.15 ENST00000596413.1
AL353583.1
AL353583.1
chr12_-_89919965 1.04 ENST00000548729.1
POC1B-GALNT4
POC1B-GALNT4 readthrough
chr11_-_615570 1.03 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
IRF7
interferon regulatory factor 7
chr4_+_8582287 0.99 ENST00000382487.4
GPR78
G protein-coupled receptor 78
chr5_-_35938674 0.95 ENST00000397366.1
ENST00000513623.1
ENST00000514524.1
ENST00000397367.2
CAPSL
calcyphosine-like
chr2_-_11810284 0.94 ENST00000306928.5
NTSR2
neurotensin receptor 2
chr11_+_313503 0.90 ENST00000528780.1
ENST00000328221.5
IFITM1
interferon induced transmembrane protein 1
chr12_-_89920030 0.90 ENST00000413530.1
ENST00000547474.1
GALNT4
POC1B-GALNT4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
POC1B-GALNT4 readthrough
chr18_+_23806437 0.85 ENST00000578121.1
TAF4B
TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr12_+_112563335 0.82 ENST00000549358.1
ENST00000257604.5
ENST00000548092.1
ENST00000552896.1
TRAFD1
TRAF-type zinc finger domain containing 1
chr12_+_112563303 0.81 ENST00000412615.2
TRAFD1
TRAF-type zinc finger domain containing 1
chrX_+_30265256 0.80 ENST00000397548.2
MAGEB1
melanoma antigen family B, 1
chr22_-_44258360 0.79 ENST00000330884.4
ENST00000249130.5
SULT4A1
sulfotransferase family 4A, member 1
chrX_+_38420783 0.78 ENST00000422612.2
ENST00000286824.6
ENST00000545599.1
TSPAN7
tetraspanin 7
chr15_-_43622736 0.78 ENST00000544735.1
ENST00000567039.1
ENST00000305641.5
LCMT2
leucine carboxyl methyltransferase 2
chr11_-_615942 0.77 ENST00000397562.3
ENST00000330243.5
ENST00000397570.1
ENST00000397574.2
IRF7
interferon regulatory factor 7
chr19_+_55851221 0.76 ENST00000255613.3
ENST00000539076.1
SUV420H2
AC020922.1
suppressor of variegation 4-20 homolog 2 (Drosophila)
Uncharacterized protein
chr4_-_170924888 0.72 ENST00000502832.1
ENST00000393704.3
MFAP3L
microfibrillar-associated protein 3-like
chr3_+_14716606 0.70 ENST00000253697.3
ENST00000435614.1
ENST00000412910.1
C3orf20
chromosome 3 open reading frame 20
chr21_+_34775181 0.66 ENST00000290219.6
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr5_+_49961727 0.65 ENST00000505697.2
ENST00000503750.2
ENST00000514342.2
PARP8
poly (ADP-ribose) polymerase family, member 8
chr7_-_103629963 0.65 ENST00000428762.1
ENST00000343529.5
ENST00000424685.2
RELN
reelin
chr17_-_39280419 0.60 ENST00000394014.1
KRTAP4-12
keratin associated protein 4-12
chr1_-_153931052 0.60 ENST00000368630.3
ENST00000368633.1
CRTC2
CREB regulated transcription coactivator 2
chr19_+_38085731 0.59 ENST00000589117.1
ZNF540
zinc finger protein 540
chr8_+_104426942 0.54 ENST00000297579.5
DCAF13
DDB1 and CUL4 associated factor 13
chr19_-_41388657 0.53 ENST00000301146.4
ENST00000291764.3
CYP2A7
cytochrome P450, family 2, subfamily A, polypeptide 7
chr19_-_48048518 0.53 ENST00000595558.1
ENST00000263351.5
ZNF541
zinc finger protein 541
chr17_+_3118915 0.53 ENST00000304094.1
OR1A1
olfactory receptor, family 1, subfamily A, member 1
chr2_-_114514181 0.51 ENST00000409342.1
SLC35F5
solute carrier family 35, member F5
chr10_+_118305435 0.51 ENST00000369221.2
PNLIP
pancreatic lipase
chr1_-_205180664 0.46 ENST00000367161.3
ENST00000367162.3
ENST00000367160.4
DSTYK
dual serine/threonine and tyrosine protein kinase
chr6_-_169654139 0.46 ENST00000366787.3
THBS2
thrombospondin 2
chr19_+_52693259 0.46 ENST00000322088.6
ENST00000454220.2
ENST00000444322.2
ENST00000477989.1
PPP2R1A
protein phosphatase 2, regulatory subunit A, alpha
chr6_+_89674246 0.45 ENST00000369474.1
AL079342.1
Uncharacterized protein; cDNA FLJ27030 fis, clone SLV07741
chr21_-_37451680 0.44 ENST00000399201.1
SETD4
SET domain containing 4
chr13_+_113623509 0.43 ENST00000535094.2
MCF2L
MCF.2 cell line derived transforming sequence-like
chr3_-_58572760 0.43 ENST00000447756.2
FAM107A
family with sequence similarity 107, member A
chr9_-_73029540 0.42 ENST00000377126.2
KLF9
Kruppel-like factor 9
chr8_+_117950422 0.40 ENST00000378279.3
AARD
alanine and arginine rich domain containing protein
chr14_-_64804814 0.39 ENST00000554572.1
ENST00000358599.5
ESR2
estrogen receptor 2 (ER beta)
chr17_-_60883993 0.38 ENST00000583803.1
ENST00000456609.2
MARCH10
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr1_-_11036272 0.38 ENST00000520253.1
C1orf127
chromosome 1 open reading frame 127
chr1_-_36851489 0.38 ENST00000373130.3
ENST00000373132.3
STK40
serine/threonine kinase 40
chr2_-_25194476 0.37 ENST00000534855.1
DNAJC27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr2_+_183982238 0.37 ENST00000442895.2
ENST00000446612.1
ENST00000409798.1
NUP35
nucleoporin 35kDa
chr1_+_171283331 0.36 ENST00000367749.3
FMO4
flavin containing monooxygenase 4
chr11_-_104972158 0.36 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
CASP1
CARD16
CARD17
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr22_+_39101728 0.35 ENST00000216044.5
ENST00000484657.1
GTPBP1
GTP binding protein 1
chrX_+_37850026 0.35 ENST00000341016.3
CXorf27
chromosome X open reading frame 27
chr6_+_31939608 0.35 ENST00000375331.2
ENST00000375333.2
STK19
serine/threonine kinase 19
chr1_-_36851475 0.35 ENST00000373129.3
STK40
serine/threonine kinase 40
chr8_+_145159376 0.34 ENST00000322428.5
MAF1
MAF1 homolog (S. cerevisiae)
chrX_+_38420623 0.34 ENST00000378482.2
TSPAN7
tetraspanin 7
chr8_+_145159415 0.34 ENST00000534585.1
MAF1
MAF1 homolog (S. cerevisiae)
chr15_-_83621435 0.32 ENST00000450735.2
ENST00000426485.1
ENST00000399166.2
ENST00000304231.8
HOMER2
homer homolog 2 (Drosophila)
chr11_+_31391381 0.32 ENST00000465995.1
ENST00000536040.1
DNAJC24
DnaJ (Hsp40) homolog, subfamily C, member 24
chr9_+_33795533 0.31 ENST00000379405.3
PRSS3
protease, serine, 3
chr1_-_205091115 0.30 ENST00000264515.6
ENST00000367164.1
RBBP5
retinoblastoma binding protein 5
chr20_-_44539538 0.30 ENST00000372420.1
PLTP
phospholipid transfer protein
chr2_-_25194963 0.29 ENST00000264711.2
DNAJC27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr10_-_106098162 0.29 ENST00000337478.1
ITPRIP
inositol 1,4,5-trisphosphate receptor interacting protein
chr4_+_128982490 0.29 ENST00000394288.3
ENST00000432347.2
ENST00000264584.5
ENST00000441387.1
ENST00000427266.1
ENST00000354456.3
LARP1B
La ribonucleoprotein domain family, member 1B
chr1_+_203444887 0.29 ENST00000343110.2
PRELP
proline/arginine-rich end leucine-rich repeat protein
chr4_+_156680153 0.29 ENST00000502959.1
ENST00000505764.1
ENST00000507146.1
ENST00000264424.8
ENST00000503520.1
GUCY1B3
guanylate cyclase 1, soluble, beta 3
chr2_+_183989157 0.28 ENST00000541912.1
NUP35
nucleoporin 35kDa
chr19_+_35168547 0.28 ENST00000502743.1
ENST00000509528.1
ENST00000506901.1
ZNF302
zinc finger protein 302
chr4_+_14113592 0.27 ENST00000502759.1
ENST00000511200.1
ENST00000512754.1
ENST00000506739.1
LINC01085
long intergenic non-protein coding RNA 1085
chrX_+_153770421 0.26 ENST00000369609.5
ENST00000369607.1
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr15_-_42783303 0.26 ENST00000565380.1
ENST00000564754.1
ZNF106
zinc finger protein 106
chr3_-_110612323 0.26 ENST00000383686.2
RP11-553A10.1
Uncharacterized protein
chr9_+_131549483 0.24 ENST00000372648.5
ENST00000539497.1
TBC1D13
TBC1 domain family, member 13
chr5_-_87516448 0.24 ENST00000511218.1
TMEM161B
transmembrane protein 161B
chr9_-_114521783 0.24 ENST00000394779.3
ENST00000394777.4
C9orf84
chromosome 9 open reading frame 84
chr4_-_168155577 0.24 ENST00000541354.1
ENST00000509854.1
ENST00000512681.1
ENST00000421836.2
ENST00000510741.1
ENST00000510403.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr15_+_45722727 0.24 ENST00000396650.2
ENST00000558435.1
ENST00000344300.3
C15orf48
chromosome 15 open reading frame 48
chr6_-_9939552 0.24 ENST00000460363.2
OFCC1
orofacial cleft 1 candidate 1
chrX_+_47077632 0.23 ENST00000457458.2
CDK16
cyclin-dependent kinase 16
chr10_+_96162242 0.23 ENST00000225235.4
TBC1D12
TBC1 domain family, member 12
chr17_+_4855053 0.23 ENST00000518175.1
ENO3
enolase 3 (beta, muscle)
chr4_-_168155730 0.22 ENST00000502330.1
ENST00000357154.3
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr6_-_32908765 0.22 ENST00000416244.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr1_+_158323244 0.22 ENST00000434258.1
CD1E
CD1e molecule
chr7_+_142031986 0.22 ENST00000547918.2
TRBV7-1
T cell receptor beta variable 7-1 (non-functional)
chr4_-_168155417 0.22 ENST00000511269.1
ENST00000506697.1
ENST00000512042.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr7_+_29519486 0.22 ENST00000409041.4
CHN2
chimerin 2
chr14_+_20937538 0.21 ENST00000361505.5
ENST00000553591.1
PNP
purine nucleoside phosphorylase
chr2_+_219524379 0.21 ENST00000443791.1
ENST00000359273.3
ENST00000392109.1
ENST00000392110.2
ENST00000423377.1
ENST00000392111.2
ENST00000412366.1
BCS1L
BC1 (ubiquinol-cytochrome c reductase) synthesis-like
chr1_+_26496362 0.21 ENST00000374266.5
ENST00000270812.5
ZNF593
zinc finger protein 593
chr1_+_158323486 0.21 ENST00000444681.2
ENST00000368167.3
CD1E
CD1e molecule
chr2_+_183989083 0.20 ENST00000295119.4
NUP35
nucleoporin 35kDa
chr2_-_219524193 0.20 ENST00000450560.1
ENST00000449707.1
ENST00000432460.1
ENST00000411696.2
ZNF142
zinc finger protein 142
chr1_+_50513686 0.19 ENST00000448907.2
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chrX_-_73834449 0.19 ENST00000332687.6
ENST00000349225.2
RLIM
ring finger protein, LIM domain interacting
chr22_+_20105259 0.18 ENST00000416427.1
ENST00000421656.1
ENST00000423859.1
ENST00000418705.2
RANBP1
RAN binding protein 1
chr14_-_24711806 0.18 ENST00000540705.1
ENST00000538777.1
ENST00000558566.1
ENST00000559019.1
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr7_-_30066233 0.18 ENST00000222803.5
FKBP14
FK506 binding protein 14, 22 kDa
chr12_+_10460549 0.18 ENST00000543420.1
ENST00000543777.1
KLRD1
killer cell lectin-like receptor subfamily D, member 1
chr9_+_104161123 0.18 ENST00000374861.3
ENST00000339664.2
ENST00000259395.4
ZNF189
zinc finger protein 189
chrX_+_68725084 0.18 ENST00000252338.4
FAM155B
family with sequence similarity 155, member B
chr18_-_59274139 0.17 ENST00000586949.1
RP11-879F14.2
RP11-879F14.2
chr12_-_69080590 0.17 ENST00000433116.2
ENST00000500695.2
RP11-637A17.2
RP11-637A17.2
chr1_-_7913089 0.17 ENST00000361696.5
UTS2
urotensin 2
chr13_+_96085847 0.17 ENST00000376873.3
CLDN10
claudin 10
chr3_-_119379427 0.16 ENST00000264231.3
ENST00000468801.1
ENST00000538678.1
POPDC2
popeye domain containing 2
chr11_+_73358594 0.16 ENST00000227214.6
ENST00000398494.4
ENST00000543085.1
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr9_+_131549610 0.16 ENST00000223865.8
TBC1D13
TBC1 domain family, member 13
chr11_+_9482551 0.16 ENST00000438144.2
ENST00000526657.1
ENST00000299606.2
ENST00000534265.1
ENST00000412390.2
ZNF143
zinc finger protein 143
chr1_+_99729813 0.16 ENST00000457765.1
LPPR4
Lipid phosphate phosphatase-related protein type 4
chr1_-_168464875 0.16 ENST00000422253.1
RP5-968D22.3
RP5-968D22.3
chr19_-_35719609 0.16 ENST00000324675.3
FAM187B
family with sequence similarity 187, member B
chr19_+_7049332 0.15 ENST00000381393.3
MBD3L2
methyl-CpG binding domain protein 3-like 2
chr8_-_10512569 0.15 ENST00000382483.3
RP1L1
retinitis pigmentosa 1-like 1
chr9_-_91793675 0.15 ENST00000375835.4
ENST00000375830.1
SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr10_+_134150835 0.15 ENST00000432555.2
LRRC27
leucine rich repeat containing 27
chr19_-_2783363 0.14 ENST00000221566.2
SGTA
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
chr16_+_27214802 0.14 ENST00000380948.2
ENST00000286096.4
KDM8
lysine (K)-specific demethylase 8
chr7_+_99816859 0.14 ENST00000317271.2
PVRIG
poliovirus receptor related immunoglobulin domain containing
chr17_-_39538550 0.14 ENST00000394001.1
KRT34
keratin 34
chr4_-_168155700 0.14 ENST00000357545.4
ENST00000512648.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr16_+_23847339 0.13 ENST00000303531.7
PRKCB
protein kinase C, beta
chr15_+_51973550 0.13 ENST00000220478.3
SCG3
secretogranin III
chr1_-_145715565 0.13 ENST00000369288.2
ENST00000369290.1
ENST00000401557.3
CD160
CD160 molecule
chrX_+_48398053 0.13 ENST00000537536.1
ENST00000418627.1
TBC1D25
TBC1 domain family, member 25
chr5_-_179498703 0.13 ENST00000522208.2
RNF130
ring finger protein 130
chr3_+_38307293 0.12 ENST00000311856.4
SLC22A13
solute carrier family 22 (organic anion/urate transporter), member 13
chr4_+_156680143 0.12 ENST00000505154.1
GUCY1B3
guanylate cyclase 1, soluble, beta 3
chr2_-_68479614 0.12 ENST00000234310.3
PPP3R1
protein phosphatase 3, regulatory subunit B, alpha
chrX_-_70326455 0.12 ENST00000374251.5
CXorf65
chromosome X open reading frame 65
chr1_+_40505891 0.11 ENST00000372797.3
ENST00000372802.1
ENST00000449311.1
CAP1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr5_+_178977546 0.11 ENST00000319449.4
ENST00000377001.2
RUFY1
RUN and FYVE domain containing 1
chr3_+_49236910 0.11 ENST00000452691.2
ENST00000366429.2
CCDC36
coiled-coil domain containing 36
chr15_+_51973680 0.11 ENST00000542355.2
SCG3
secretogranin III
chr19_+_38085768 0.11 ENST00000316433.4
ENST00000590588.1
ENST00000586134.1
ENST00000586792.1
ZNF540
zinc finger protein 540
chr1_+_202830876 0.11 ENST00000456105.2
RP11-480I12.7
RP11-480I12.7
chr21_-_30365136 0.10 ENST00000361371.5
ENST00000389194.2
ENST00000389195.2
LTN1
listerin E3 ubiquitin protein ligase 1
chr6_-_109804412 0.10 ENST00000230122.3
ZBTB24
zinc finger and BTB domain containing 24
chr10_-_102289611 0.10 ENST00000299166.4
ENST00000370320.4
ENST00000531258.1
ENST00000370322.1
ENST00000535773.1
NDUFB8
SEC31B
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa
SEC31 homolog B (S. cerevisiae)
chr3_+_127770455 0.09 ENST00000464451.1
SEC61A1
Sec61 alpha 1 subunit (S. cerevisiae)
chr19_-_46296011 0.09 ENST00000377735.3
ENST00000270223.6
DMWD
dystrophia myotonica, WD repeat containing
chr12_-_10562356 0.09 ENST00000309384.1
KLRC4
killer cell lectin-like receptor subfamily C, member 4
chr2_+_242811874 0.09 ENST00000343216.3
CXXC11
CXXC finger protein 11
chr16_-_71523179 0.08 ENST00000564230.1
ENST00000565637.1
ZNF19
zinc finger protein 19
chr2_-_227050079 0.08 ENST00000423838.1
AC068138.1
AC068138.1
chr12_+_10460417 0.08 ENST00000381908.3
ENST00000336164.4
ENST00000350274.5
KLRD1
killer cell lectin-like receptor subfamily D, member 1
chr15_+_81591757 0.08 ENST00000558332.1
IL16
interleukin 16
chr2_-_44065889 0.08 ENST00000543989.1
ENST00000405322.1
ABCG5
ATP-binding cassette, sub-family G (WHITE), member 5
chr11_+_65122216 0.07 ENST00000309880.5
TIGD3
tigger transposable element derived 3
chr19_+_2841433 0.07 ENST00000334241.4
ENST00000585966.1
ENST00000591539.1
ZNF555
zinc finger protein 555
chr6_-_30815936 0.07 ENST00000442852.1
XXbac-BPG27H4.8
XXbac-BPG27H4.8
chr20_-_23807358 0.06 ENST00000304725.2
CST2
cystatin SA
chr11_+_9482512 0.05 ENST00000396602.2
ENST00000530463.1
ENST00000533542.1
ENST00000532577.1
ENST00000396597.3
ZNF143
zinc finger protein 143
chr19_+_32836499 0.05 ENST00000311921.4
ENST00000544431.1
ENST00000355898.5
ZNF507
zinc finger protein 507
chrX_-_48931648 0.05 ENST00000376386.3
ENST00000376390.4
PRAF2
PRA1 domain family, member 2
chr12_-_75603643 0.05 ENST00000549446.1
KCNC2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr16_-_71523236 0.05 ENST00000288177.5
ENST00000569072.1
ZNF19
zinc finger protein 19
chr16_-_52640834 0.04 ENST00000510238.3
CASC16
cancer susceptibility candidate 16 (non-protein coding)
chr8_-_145159083 0.04 ENST00000398712.2
SHARPIN
SHANK-associated RH domain interactor
chr19_+_35168633 0.04 ENST00000505365.2
ZNF302
zinc finger protein 302
chr12_-_53594227 0.04 ENST00000550743.2
ITGB7
integrin, beta 7
chr4_+_128982430 0.03 ENST00000512292.1
ENST00000508819.1
LARP1B
La ribonucleoprotein domain family, member 1B
chr6_-_32908792 0.03 ENST00000418107.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr1_+_247670415 0.03 ENST00000366491.2
ENST00000366489.1
ENST00000526896.1
GCSAML
germinal center-associated, signaling and motility-like
chrX_+_70364667 0.03 ENST00000536169.1
ENST00000395855.2
ENST00000374051.3
ENST00000358741.3
NLGN3
neuroligin 3
chr16_-_75018968 0.03 ENST00000262144.6
WDR59
WD repeat domain 59
chr19_-_42463418 0.03 ENST00000600292.1
ENST00000601078.1
ENST00000601891.1
ENST00000222008.6
RABAC1
Rab acceptor 1 (prenylated)
chr19_+_4343691 0.03 ENST00000597036.1
MPND
MPN domain containing
chr7_+_142457315 0.03 ENST00000486171.1
ENST00000311737.7
PRSS1
protease, serine, 1 (trypsin 1)
chr4_+_15376165 0.03 ENST00000382383.3
ENST00000429690.1
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr14_+_22217447 0.02 ENST00000390427.3
TRAV5
T cell receptor alpha variable 5
chr5_+_69345350 0.02 ENST00000380741.4
ENST00000380743.4
ENST00000511812.1
ENST00000380742.4
SMN2
survival of motor neuron 2, centromeric
chr19_-_54784353 0.02 ENST00000391746.1
LILRB2
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
chr21_-_31744557 0.02 ENST00000399889.2
KRTAP13-2
keratin associated protein 13-2
chr8_-_101718991 0.02 ENST00000517990.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr12_-_127544894 0.02 ENST00000546062.1
ENST00000512624.2
ENST00000540244.1
RP11-575F12.1
RP11-575F12.1
chr8_+_125463048 0.02 ENST00000328599.3
TRMT12
tRNA methyltransferase 12 homolog (S. cerevisiae)
chr1_-_153123345 0.01 ENST00000368748.4
SPRR2G
small proline-rich protein 2G
chr2_+_171034646 0.01 ENST00000409044.3
ENST00000408978.4
MYO3B
myosin IIIB
chrX_-_13835461 0.01 ENST00000316715.4
ENST00000356942.5
GPM6B
glycoprotein M6B
chr12_+_652294 0.01 ENST00000322843.3
B4GALNT3
beta-1,4-N-acetyl-galactosaminyl transferase 3
chr17_-_3461092 0.00 ENST00000301365.4
ENST00000572519.1
TRPV3
transient receptor potential cation channel, subfamily V, member 3
chr5_+_70220768 0.00 ENST00000351205.4
ENST00000503079.2
ENST00000380707.4
ENST00000514951.1
ENST00000506163.1
SMN1
survival of motor neuron 1, telomeric

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.9 GO:0022614 membrane to membrane docking(GO:0022614)
0.4 1.8 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.2 2.3 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.2 1.5 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.2 0.6 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.1 0.7 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 0.5 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.1 0.7 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.1 3.5 GO:0030728 ovulation(GO:0030728)
0.1 0.4 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.1 0.3 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.1 0.3 GO:0042360 vitamin E metabolic process(GO:0042360)
0.1 0.2 GO:0046495 nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
0.1 2.1 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 0.5 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 0.4 GO:0051414 response to cortisol(GO:0051414)
0.1 0.5 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.1 0.2 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.1 0.9 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.1 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.0 0.1 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.4 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.8 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.6 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.1 GO:0039019 pronephric nephron development(GO:0039019)
0.0 0.4 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.2 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.0 0.3 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.0 0.5 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.3 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.7 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.6 GO:0030299 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0 0.2 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 1.6 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 0.7 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.2 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.4 GO:0042737 drug catabolic process(GO:0042737)
0.0 0.8 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.8 GO:0003016 respiratory system process(GO:0003016)
0.0 0.1 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.2 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.3 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.8 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.4 GO:1900116 extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.5 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.3 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.9 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.1 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.0 0.2 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.1 0.4 GO:0072558 NLRP1 inflammasome complex(GO:0072558) protease inhibitor complex(GO:0097179)
0.1 0.9 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.2 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.0 0.7 GO:0060077 inhibitory synapse(GO:0060077)
0.0 3.2 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.3 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.7 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.5 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.6 GO:0008131 primary amine oxidase activity(GO:0008131)
0.2 0.7 GO:0000994 RNA polymerase III core binding(GO:0000994)
0.2 0.6 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.1 0.7 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.1 3.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 2.1 GO:0051400 BH domain binding(GO:0051400)
0.1 0.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 0.2 GO:0000035 acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)
0.1 0.2 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.1 0.3 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.8 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.4 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.0 0.4 GO:0030882 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.0 0.3 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.8 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.4 GO:0089720 caspase binding(GO:0089720)
0.0 0.5 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.8 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.7 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.9 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.7 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 1.5 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.2 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.5 GO:0030331 estrogen receptor binding(GO:0030331)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.0 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 4.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.6 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.8 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 0.7 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 5.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.3 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.5 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.7 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.3 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.7 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.5 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D