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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for PAX6

Z-value: 0.70

Motif logo

Transcription factors associated with PAX6

Gene Symbol Gene ID Gene Info
ENSG00000007372.16 paired box 6

Activity-expression correlation:

Activity profile of PAX6 motif

Sorted Z-values of PAX6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_13372253 1.04 ENST00000316609.5
deleted in liver cancer 1
chr9_-_5185629 1.02 ENST00000381641.3
insulin-like 6
chr12_-_47473425 0.87 ENST00000550413.1
adhesion molecule with Ig-like domain 2
chr1_+_79115503 0.83 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
interferon-induced protein 44
chr1_-_36906474 0.83 ENST00000433045.2
organic solute carrier partner 1
chr14_+_29241910 0.82 ENST00000399387.4
ENST00000552957.1
ENST00000548213.1
chromosome 14 open reading frame 23
chr12_+_113354341 0.78 ENST00000553152.1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr12_-_47473707 0.73 ENST00000429635.1
adhesion molecule with Ig-like domain 2
chr12_+_6949964 0.72 ENST00000541978.1
ENST00000435982.2
guanine nucleotide binding protein (G protein), beta polypeptide 3
chr16_+_618837 0.72 ENST00000409439.2
phosphatidylinositol glycan anchor biosynthesis, class Q
chr18_+_18822185 0.71 ENST00000424526.1
ENST00000400483.4
ENST00000431264.1
growth regulation by estrogen in breast cancer-like
chr1_+_104068562 0.70 ENST00000423855.2
RNA-binding region (RNP1, RRM) containing 3
chr2_-_86116093 0.68 ENST00000377332.3
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr6_+_147527103 0.62 ENST00000179882.6
syntaxin binding protein 5 (tomosyn)
chr6_-_85474219 0.61 ENST00000369663.5
T-box 18
chr4_-_88141755 0.58 ENST00000273963.5
kelch-like family member 8
chr20_-_44144249 0.56 ENST00000217428.6
serine peptidase inhibitor, Kunitz type, 3
chr4_-_88141615 0.55 ENST00000545252.1
ENST00000425278.2
ENST00000498875.2
kelch-like family member 8
chr8_-_95487331 0.54 ENST00000336148.5
RAD54 homolog B (S. cerevisiae)
chr18_+_18822216 0.51 ENST00000269218.6
growth regulation by estrogen in breast cancer-like
chr11_-_28129656 0.50 ENST00000263181.6
kinesin family member 18A
chr12_-_10151773 0.47 ENST00000298527.6
ENST00000348658.4
C-type lectin domain family 1, member B
chr16_-_80926457 0.45 ENST00000563626.1
ENST00000562231.1
RP11-314O13.1
chr2_+_109204909 0.44 ENST00000393310.1
LIM and senescent cell antigen-like domains 1
chr3_-_122512619 0.44 ENST00000383659.1
ENST00000306103.2
HSPB (heat shock 27kDa) associated protein 1
chr7_-_97501706 0.39 ENST00000455086.1
ENST00000453600.1
asparagine synthetase (glutamine-hydrolyzing)
chr7_-_138348969 0.38 ENST00000436657.1
SVOP-like
chr12_+_83080659 0.38 ENST00000321196.3
transmembrane and tetratricopeptide repeat containing 2
chr6_-_31846744 0.38 ENST00000414427.1
ENST00000229729.6
ENST00000375562.4
solute carrier family 44, member 4
chr9_-_113100088 0.37 ENST00000374510.4
ENST00000423740.2
ENST00000374511.3
ENST00000374507.4
thioredoxin domain containing 8 (spermatozoa)
chr1_-_144932014 0.35 ENST00000529945.1
phosphodiesterase 4D interacting protein
chr9_+_42704004 0.35 ENST00000457288.1
COBW domain containing 7
chr10_+_12110963 0.34 ENST00000263035.4
ENST00000437298.1
dehydrogenase E1 and transketolase domain containing 1
chr4_+_77356248 0.34 ENST00000296043.6
shroom family member 3
chr20_-_1472029 0.34 ENST00000359801.3
signal-regulatory protein beta 2
chr12_-_10007448 0.33 ENST00000538152.1
C-type lectin domain family 2, member B
chr19_-_54327542 0.33 ENST00000391775.3
ENST00000324134.6
ENST00000535162.1
ENST00000351894.4
ENST00000354278.3
ENST00000391773.1
ENST00000345770.5
ENST00000391772.1
NLR family, pyrin domain containing 12
chr3_+_151531810 0.33 ENST00000232892.7
arylacetamide deacetylase
chr2_-_165812028 0.33 ENST00000303735.4
solute carrier family 38, member 11
chr5_-_159546396 0.32 ENST00000523662.1
ENST00000456329.3
ENST00000307063.7
PWWP domain containing 2A
chr11_-_58343319 0.32 ENST00000395074.2
leupaxin
chr5_-_160279207 0.31 ENST00000327245.5
ATPase, class V, type 10B
chr19_-_37701386 0.31 ENST00000527838.1
ENST00000591492.1
ENST00000532828.2
zinc finger protein 585B
chr7_+_76109827 0.31 ENST00000446820.2
deltex homolog 2 (Drosophila)
chr7_-_97501733 0.31 ENST00000444334.1
ENST00000422745.1
ENST00000394308.3
ENST00000451771.1
ENST00000175506.4
asparagine synthetase (glutamine-hydrolyzing)
chr11_+_28129795 0.31 ENST00000406787.3
ENST00000342303.5
ENST00000403099.1
ENST00000407364.3
methyltransferase like 15
chr16_-_67450325 0.30 ENST00000348579.2
zinc finger, DHHC-type containing 1
chr4_-_69215467 0.28 ENST00000579690.1
YTH domain containing 1
chr20_+_62887081 0.28 ENST00000369758.4
ENST00000299468.7
ENST00000609372.1
ENST00000610196.1
ENST00000308824.6
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
chr4_+_187148556 0.28 ENST00000264690.6
ENST00000446598.2
ENST00000414291.1
ENST00000513864.1
kallikrein B, plasma (Fletcher factor) 1
chr1_-_43282906 0.27 ENST00000372521.4
coiled-coil domain containing 23
chr13_+_53602894 0.27 ENST00000219022.2
olfactomedin 4
chr1_-_43282945 0.27 ENST00000537227.1
coiled-coil domain containing 23
chr1_+_2005425 0.27 ENST00000461106.2
protein kinase C, zeta
chr16_+_77822427 0.26 ENST00000302536.2
vesicle amine transport 1-like
chr19_-_57347415 0.26 ENST00000601070.1
zinc finger, imprinted 2
chr4_+_70916119 0.26 ENST00000246896.3
ENST00000511674.1
histatin 1
chr19_-_10047219 0.26 ENST00000264833.4
olfactomedin 2
chr8_+_16884740 0.25 ENST00000318063.5
mitochondrial calcium uptake family, member 3
chr7_-_150864635 0.25 ENST00000297537.4
gastrulation brain homeobox 1
chr2_+_114195268 0.25 ENST00000259199.4
ENST00000416503.2
ENST00000433343.2
COBW domain containing 2
chr4_+_87928140 0.25 ENST00000307808.6
AF4/FMR2 family, member 1
chr2_-_29093132 0.25 ENST00000306108.5
tRNA methyltransferase 61 homolog B (S. cerevisiae)
chr10_-_118765081 0.25 ENST00000392903.2
ENST00000355371.4
KIAA1598
chr4_+_76995855 0.24 ENST00000355810.4
ENST00000349321.3
ADP-ribosyltransferase 3
chr9_-_14180778 0.24 ENST00000380924.1
ENST00000543693.1
nuclear factor I/B
chr3_-_119379719 0.24 ENST00000493094.1
popeye domain containing 2
chr6_+_125475335 0.23 ENST00000532429.1
ENST00000534199.1
tumor protein D52-like 1
chr3_-_101232019 0.23 ENST00000394095.2
ENST00000394091.1
ENST00000394094.2
ENST00000358203.3
ENST00000348610.3
ENST00000314261.7
SUMO1/sentrin specific peptidase 7
chr2_+_202098166 0.23 ENST00000392263.2
ENST00000264274.9
ENST00000392259.2
ENST00000392266.3
ENST00000432109.2
ENST00000264275.5
caspase 8, apoptosis-related cysteine peptidase
chr6_+_88299833 0.22 ENST00000392844.3
ENST00000257789.4
ENST00000546266.1
ENST00000417380.2
origin recognition complex, subunit 3
chr4_-_68749745 0.22 ENST00000283916.6
transmembrane protease, serine 11D
chr4_+_115519577 0.22 ENST00000310836.6
UDP glycosyltransferase 8
chrX_-_124097620 0.22 ENST00000371130.3
ENST00000422452.2
teneurin transmembrane protein 1
chr4_-_68749699 0.22 ENST00000545541.1
transmembrane protease, serine 11D
chr16_-_3767551 0.21 ENST00000246957.5
TNF receptor-associated protein 1
chr10_-_118764862 0.21 ENST00000260777.10
KIAA1598
chr7_-_152373216 0.20 ENST00000359321.1
X-ray repair complementing defective repair in Chinese hamster cells 2
chr1_+_163291732 0.20 ENST00000271452.3
NUF2, NDC80 kinetochore complex component
chr11_-_117747434 0.20 ENST00000529335.2
ENST00000530956.1
ENST00000260282.4
FXYD domain containing ion transport regulator 6
chr11_-_117748138 0.20 ENST00000527717.1
FXYD domain containing ion transport regulator 6
chr10_-_27389320 0.19 ENST00000436985.2
ankyrin repeat domain 26
chr17_-_77023723 0.19 ENST00000577521.1
C1QTNF1 antisense RNA 1
chr21_+_39628852 0.19 ENST00000398938.2
potassium inwardly-rectifying channel, subfamily J, member 15
chr1_-_86174065 0.19 ENST00000370574.3
ENST00000431532.2
zinc finger, HIT-type containing 6
chr10_+_114135952 0.19 ENST00000356116.1
ENST00000433418.1
ENST00000354273.4
acyl-CoA synthetase long-chain family member 5
chr16_+_77233294 0.19 ENST00000378644.4
synaptonemal complex central element protein 1-like
chr12_-_3982511 0.18 ENST00000427057.2
ENST00000228820.4
poly (ADP-ribose) polymerase family, member 11
chr16_-_3767506 0.18 ENST00000538171.1
TNF receptor-associated protein 1
chr3_-_142297668 0.18 ENST00000350721.4
ENST00000383101.3
ataxia telangiectasia and Rad3 related
chr5_+_79615790 0.18 ENST00000296739.4
spermatogenic leucine zipper 1
chr11_-_117747607 0.18 ENST00000540359.1
ENST00000539526.1
FXYD domain containing ion transport regulator 6
chr10_-_27389392 0.17 ENST00000376087.4
ankyrin repeat domain 26
chr11_+_4788500 0.17 ENST00000380390.1
matrix metallopeptidase 26
chr6_-_134373732 0.17 ENST00000275230.5
solute carrier family 2 (facilitated glucose transporter), member 12
chr7_+_90012986 0.17 ENST00000416322.1
claudin 12
chr20_+_48807351 0.17 ENST00000303004.3
CCAAT/enhancer binding protein (C/EBP), beta
chr14_+_88471468 0.17 ENST00000267549.3
G protein-coupled receptor 65
chr18_+_32173276 0.17 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
dystrobrevin, alpha
chr2_-_40680578 0.17 ENST00000455476.1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr5_+_93954039 0.17 ENST00000265140.5
ankyrin repeat domain 32
chr19_+_15852203 0.17 ENST00000305892.1
olfactory receptor, family 10, subfamily H, member 3
chr2_-_85625857 0.16 ENST00000453973.1
capping protein (actin filament), gelsolin-like
chr9_+_131549610 0.16 ENST00000223865.8
TBC1 domain family, member 13
chr7_+_90338712 0.16 ENST00000265741.3
ENST00000406263.1
cyclin-dependent kinase 14
chr9_+_131549483 0.16 ENST00000372648.5
ENST00000539497.1
TBC1 domain family, member 13
chr1_-_247697141 0.16 ENST00000366487.3
olfactory receptor, family 2, subfamily C, member 3
chr4_+_129349188 0.16 ENST00000511497.1
RP11-420A23.1
chr6_+_125474939 0.16 ENST00000527711.1
tumor protein D52-like 1
chr21_-_35014027 0.16 ENST00000399442.1
ENST00000413017.2
ENST00000445393.1
ENST00000417979.1
ENST00000426935.1
ENST00000381540.3
ENST00000361534.2
ENST00000381554.3
crystallin, zeta (quinone reductase)-like 1
chr18_-_21242774 0.16 ENST00000322980.9
ankyrin repeat domain 29
chr6_+_170151708 0.16 ENST00000592367.1
ENST00000590711.1
ENST00000366772.2
ENST00000592745.1
ENST00000392095.4
ENST00000366773.3
ENST00000586341.1
ENST00000418781.3
ENST00000588437.1
ER membrane-associated RNA degradation
chr12_-_5352315 0.16 ENST00000536518.1
RP11-319E16.1
chr15_+_52043758 0.16 ENST00000249700.4
ENST00000539962.2
tropomodulin 2 (neuronal)
chr5_+_42756903 0.15 ENST00000361970.5
ENST00000388827.4
coiled-coil domain containing 152
chr6_+_125474992 0.15 ENST00000528193.1
tumor protein D52-like 1
chr6_-_2634820 0.14 ENST00000296847.3
chromosome 6 open reading frame 195
chr12_-_3982548 0.14 ENST00000397096.2
ENST00000447133.3
ENST00000450737.2
poly (ADP-ribose) polymerase family, member 11
chr8_-_121457608 0.14 ENST00000306185.3
mitochondrial ribosomal protein L13
chr7_-_14029283 0.13 ENST00000433547.1
ENST00000405192.2
ets variant 1
chr3_-_15563229 0.13 ENST00000383786.5
ENST00000383787.2
ENST00000383785.2
ENST00000383788.5
ENST00000603808.1
collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
chr9_-_116861337 0.13 ENST00000374118.3
kinesin family member 12
chr19_-_51920835 0.13 ENST00000442846.3
ENST00000530476.1
sialic acid binding Ig-like lectin 10
chrX_+_37545012 0.13 ENST00000378616.3
X-linked Kx blood group (McLeod syndrome)
chr4_-_16077741 0.13 ENST00000447510.2
ENST00000540805.1
ENST00000539194.1
prominin 1
chr2_+_220363579 0.13 ENST00000313597.5
ENST00000373917.3
ENST00000358215.3
ENST00000373908.1
ENST00000455657.1
ENST00000435316.1
ENST00000341142.3
GDP-mannose pyrophosphorylase A
chr2_+_179184955 0.13 ENST00000315022.2
oxysterol binding protein-like 6
chr2_-_677369 0.13 ENST00000281017.3
transmembrane protein 18
chr17_+_43224684 0.13 ENST00000332499.2
hexamethylene bis-acetamide inducible 1
chr3_-_58652523 0.13 ENST00000489857.1
ENST00000358781.2
family with sequence similarity 3, member D
chr15_-_56757329 0.12 ENST00000260453.3
meiosis-specific nuclear structural 1
chr1_+_87380299 0.12 ENST00000370551.4
ENST00000370550.5
heparan sulfate 2-O-sulfotransferase 1
chr4_+_123747834 0.12 ENST00000264498.3
fibroblast growth factor 2 (basic)
chr7_+_138943265 0.12 ENST00000483726.1
ubinuclein 2
chr5_+_140254884 0.12 ENST00000398631.2
protocadherin alpha 12
chr16_+_4897912 0.12 ENST00000545171.1
ubinuclein 1
chr6_+_1080164 0.11 ENST00000314040.1
Uncharacterized protein; cDNA FLJ34594 fis, clone KIDNE2009109
chr2_-_136743169 0.11 ENST00000264161.4
aspartyl-tRNA synthetase
chr5_+_94982558 0.11 ENST00000311364.4
ENST00000458310.1
Rieske (Fe-S) domain containing
chr3_-_15540055 0.11 ENST00000605797.1
ENST00000435459.2
collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
chr1_+_167298281 0.11 ENST00000367862.5
POU class 2 homeobox 1
chr18_+_61445007 0.11 ENST00000447428.1
ENST00000546027.1
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr1_-_85725316 0.10 ENST00000344356.5
ENST00000471115.1
chromosome 1 open reading frame 52
chr22_-_17702729 0.10 ENST00000449907.2
ENST00000441548.1
ENST00000399839.1
cat eye syndrome chromosome region, candidate 1
chr17_-_39041479 0.10 ENST00000167588.3
keratin 20
chr10_+_90354503 0.10 ENST00000531458.1
lipase, family member J
chr7_-_91808845 0.10 ENST00000343318.5
leucine-rich repeats and death domain containing 1
chr2_+_196521845 0.10 ENST00000359634.5
ENST00000412905.1
solute carrier family 39 (zinc transporter), member 10
chr16_-_18911366 0.09 ENST00000565224.1
SMG1 phosphatidylinositol 3-kinase-related kinase
chrX_-_64196351 0.09 ENST00000374839.3
zinc finger, C4H2 domain containing
chr1_-_23504176 0.09 ENST00000302291.4
leucine zipper protein 1
chrX_-_130423386 0.09 ENST00000370903.3
immunoglobulin superfamily, member 1
chr6_-_88299678 0.09 ENST00000369536.5
arginyl-tRNA synthetase 2, mitochondrial
chr12_-_121476959 0.09 ENST00000339275.5
2'-5'-oligoadenylate synthetase-like
chr19_-_14911023 0.09 ENST00000248073.2
olfactory receptor, family 7, subfamily C, member 1
chr10_-_104597286 0.09 ENST00000369887.3
cytochrome P450, family 17, subfamily A, polypeptide 1
chr19_-_51920873 0.09 ENST00000441969.3
ENST00000525998.1
ENST00000436984.2
sialic acid binding Ig-like lectin 10
chr8_-_33370607 0.09 ENST00000360742.5
ENST00000523305.1
TELO2 interacting protein 2
chr4_+_113970772 0.09 ENST00000504454.1
ENST00000394537.3
ENST00000357077.4
ENST00000264366.6
ankyrin 2, neuronal
chr12_-_2986107 0.09 ENST00000359843.3
ENST00000342628.2
ENST00000361953.3
forkhead box M1
chr16_-_15982440 0.09 ENST00000575938.1
ENST00000573396.1
ENST00000573968.1
ENST00000575744.1
ENST00000573429.1
ENST00000255759.6
ENST00000575073.1
FGFR1OP N-terminal like
chr11_+_118175132 0.09 ENST00000361763.4
CD3e molecule, epsilon (CD3-TCR complex)
chr8_-_21771182 0.09 ENST00000523932.1
ENST00000544659.1
docking protein 2, 56kDa
chr7_+_39773160 0.09 ENST00000340510.4
long intergenic non-protein coding RNA 265
chrX_-_64196376 0.09 ENST00000447788.2
zinc finger, C4H2 domain containing
chr8_+_49984894 0.09 ENST00000522267.1
ENST00000399653.4
ENST00000303202.8
chromosome 8 open reading frame 22
chr9_+_134065506 0.09 ENST00000483497.2
nucleoporin 214kDa
chr10_-_13523073 0.09 ENST00000440282.1
BEN domain containing 7
chr17_-_79633590 0.08 ENST00000374741.3
ENST00000571503.1
oxidoreductase-like domain containing 1
chr9_-_95166884 0.08 ENST00000375561.5
osteoglycin
chr17_-_77023683 0.08 ENST00000581579.1
C1QTNF1 antisense RNA 1
chr2_-_161056762 0.08 ENST00000428609.2
ENST00000409967.2
integrin, beta 6
chr8_-_95487272 0.08 ENST00000297592.5
RAD54 homolog B (S. cerevisiae)
chr13_-_24007815 0.08 ENST00000382298.3
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr8_-_21771214 0.08 ENST00000276420.4
docking protein 2, 56kDa
chrX_-_64196307 0.08 ENST00000545618.1
zinc finger, C4H2 domain containing
chr6_-_117923520 0.08 ENST00000368498.2
golgi-associated PDZ and coiled-coil motif containing
chr2_+_191334212 0.08 ENST00000444317.1
ENST00000535751.1
major facilitator superfamily domain containing 6
chr14_+_57671888 0.08 ENST00000391612.1
AL391152.1
chr5_+_3596168 0.08 ENST00000302006.3
iroquois homeobox 1
chr6_-_52705641 0.07 ENST00000370989.2
glutathione S-transferase alpha 5
chr1_-_87380002 0.07 ENST00000331835.5
Homo sapiens 15 kDa selenoprotein (SEP15), transcript variant 2, mRNA.
chr5_-_169725231 0.07 ENST00000046794.5
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr17_+_72270429 0.07 ENST00000311014.6
dynein, axonemal, intermediate chain 2
chr16_+_89228757 0.07 ENST00000565008.1
long intergenic non-protein coding RNA 304
chr12_+_122516626 0.07 ENST00000319080.7
MLX interacting protein
chr11_-_102576537 0.07 ENST00000260229.4
matrix metallopeptidase 27
chr10_+_102222798 0.07 ENST00000343737.5
wingless-type MMTV integration site family, member 8B
chrX_-_130423200 0.07 ENST00000361420.3
immunoglobulin superfamily, member 1
chrX_-_13835147 0.07 ENST00000493677.1
ENST00000355135.2
glycoprotein M6B
chr6_+_125474795 0.07 ENST00000304877.13
ENST00000534000.1
ENST00000368402.5
ENST00000368388.2
tumor protein D52-like 1
chr2_-_162931052 0.07 ENST00000360534.3
dipeptidyl-peptidase 4
chr11_+_134094508 0.07 ENST00000281187.5
ENST00000525095.2
vacuolar protein sorting 26 homolog B (S. pombe)
chr2_+_196521458 0.07 ENST00000409086.3
solute carrier family 39 (zinc transporter), member 10
chr11_-_117747327 0.07 ENST00000584230.1
ENST00000527429.1
ENST00000584394.1
ENST00000532984.1
FXYD domain containing ion transport regulator 6
FXYD6-FXYD2 readthrough
chr2_+_98986400 0.07 ENST00000272602.2
cyclic nucleotide gated channel alpha 3
chr15_-_23034322 0.07 ENST00000539711.2
ENST00000560039.1
ENST00000398013.3
ENST00000337451.3
ENST00000359727.4
ENST00000398014.2
non imprinted in Prader-Willi/Angelman syndrome 2
chr19_-_41903161 0.07 ENST00000602129.1
ENST00000593771.1
ENST00000596905.1
ENST00000221233.4
exosome component 5
chr19_+_35939154 0.07 ENST00000599180.2
free fatty acid receptor 2
chr12_-_70093065 0.06 ENST00000553096.1
bestrophin 3

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0060823 canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060823)
0.2 0.7 GO:0070982 L-asparagine biosynthetic process(GO:0070981) L-asparagine metabolic process(GO:0070982)
0.1 0.4 GO:0009386 translational attenuation(GO:0009386)
0.1 0.3 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.1 0.6 GO:0008291 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.1 0.2 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 0.3 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588) regulation of interleukin-18 production(GO:0032661)
0.1 1.0 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 0.2 GO:1904868 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.1 0.3 GO:0019230 proprioception(GO:0019230)
0.0 0.7 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0031133 regulation of axon diameter(GO:0031133)
0.0 0.3 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.3 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.0 0.2 GO:0039513 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.2 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.5 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.3 GO:2000664 positive regulation of interleukin-5 secretion(GO:2000664)
0.0 0.1 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.1 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.0 0.4 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.1 GO:0021503 neural fold bending(GO:0021503)
0.0 0.7 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.3 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.1 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.2 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.2 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 1.8 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.4 GO:0045176 apical protein localization(GO:0045176)
0.0 0.1 GO:0010716 negative regulation of extracellular matrix disassembly(GO:0010716)
0.0 0.2 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.1 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.0 0.6 GO:0006312 mitotic recombination(GO:0006312)
0.0 0.2 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.1 GO:0072086 specification of loop of Henle identity(GO:0072086) pattern specification involved in metanephros development(GO:0072268)
0.0 0.1 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.5 GO:0030220 platelet formation(GO:0030220)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.3 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.3 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.1 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.2 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.0 GO:2000910 regulation of very-low-density lipoprotein particle remodeling(GO:0010901) negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903) negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910)
0.0 0.1 GO:1900063 regulation of peroxisome organization(GO:1900063)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.1 0.7 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 0.5 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.2 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.3 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.1 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.8 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.2 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.3 GO:0045179 axon hillock(GO:0043203) apical cortex(GO:0045179)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.8 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.0 GO:1990716 axonemal central apparatus(GO:1990716)
0.0 0.0 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0030626 U12 snRNA binding(GO:0030626)
0.2 0.6 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.7 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.1 0.9 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.4 GO:0045118 azole transporter activity(GO:0045118)
0.1 0.2 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.1 0.7 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.3 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.3 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.7 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.3 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.4 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.2 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.2 GO:0034711 inhibin binding(GO:0034711)
0.0 0.2 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.3 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.2 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0000150 recombinase activity(GO:0000150)
0.0 1.0 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.2 GO:0032407 MutSalpha complex binding(GO:0032407)
0.0 0.0 GO:0046848 hydroxyapatite binding(GO:0046848)
0.0 0.1 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.3 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.3 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.2 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 0.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.1 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.1 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056)
0.0 0.0 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.0 0.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.2 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.2 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.1 PID RHOA REG PATHWAY Regulation of RhoA activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.7 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.7 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.2 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.4 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters