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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for PAX8

Z-value: 0.92

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Transcription factors associated with PAX8

Gene Symbol Gene ID Gene Info
PAX8
ENSG00000125618.12 paired box 8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PAX8hg19_v2_chr2_-_113999260_113999274-0.423.7e-02Click!

Activity profile of PAX8 motif

Sorted Z-values of PAX8 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_169703203 7.14 ENST00000333360.7
ENST00000367781.4
ENST00000367782.4
ENST00000367780.4
ENST00000367779.4
SELE
selectin E
chr6_-_44233361 3.05 ENST00000275015.5
NFKBIE
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr11_+_20044600 2.84 ENST00000311043.8
NAV2
neuron navigator 2
chr15_+_67420441 2.71 ENST00000558894.1
SMAD3
SMAD family member 3
chr14_-_91710852 2.60 ENST00000535815.1
ENST00000529102.1
GPR68
G protein-coupled receptor 68
chr1_-_173176452 2.48 ENST00000281834.3
TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr11_+_20044096 2.28 ENST00000533917.1
NAV2
neuron navigator 2
chr6_+_14117872 1.91 ENST00000379153.3
CD83
CD83 molecule
chr6_-_134639180 1.72 ENST00000367858.5
SGK1
serum/glucocorticoid regulated kinase 1
chr12_+_26348582 1.66 ENST00000535504.1
SSPN
sarcospan
chr17_+_80332153 1.64 ENST00000313135.2
UTS2R
urotensin 2 receptor
chr16_+_66442411 1.55 ENST00000499966.1
LINC00920
long intergenic non-protein coding RNA 920
chr22_+_21133469 1.54 ENST00000406799.1
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr6_-_82462425 1.44 ENST00000369754.3
ENST00000320172.6
ENST00000369756.3
FAM46A
family with sequence similarity 46, member A
chr12_-_129308487 1.37 ENST00000266771.5
SLC15A4
solute carrier family 15 (oligopeptide transporter), member 4
chr12_-_89919965 1.36 ENST00000548729.1
POC1B-GALNT4
POC1B-GALNT4 readthrough
chr3_+_11178779 1.30 ENST00000438284.2
HRH1
histamine receptor H1
chr14_+_22458631 1.23 ENST00000390444.1
TRAV16
T cell receptor alpha variable 16
chr1_-_231004220 1.20 ENST00000366663.5
C1orf198
chromosome 1 open reading frame 198
chr6_+_29274403 1.19 ENST00000377160.2
OR14J1
olfactory receptor, family 14, subfamily J, member 1
chr22_+_21128167 1.17 ENST00000215727.5
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr12_-_56236734 1.11 ENST00000548629.1
MMP19
matrix metallopeptidase 19
chr4_-_69536346 1.06 ENST00000338206.5
UGT2B15
UDP glucuronosyltransferase 2 family, polypeptide B15
chr3_-_189840223 1.05 ENST00000427335.2
LEPREL1
leprecan-like 1
chr10_+_85933494 0.98 ENST00000372126.3
C10orf99
chromosome 10 open reading frame 99
chr12_+_75874460 0.98 ENST00000266659.3
GLIPR1
GLI pathogenesis-related 1
chr7_+_128312346 0.92 ENST00000480462.1
ENST00000378704.3
ENST00000477515.1
FAM71F2
family with sequence similarity 71, member F2
chr2_+_161993465 0.90 ENST00000457476.1
TANK
TRAF family member-associated NFKB activator
chr12_+_72058130 0.90 ENST00000547843.1
THAP2
THAP domain containing, apoptosis associated protein 2
chr9_+_111624577 0.89 ENST00000333999.3
ACTL7A
actin-like 7A
chr1_+_159409512 0.89 ENST00000423932.3
OR10J1
olfactory receptor, family 10, subfamily J, member 1
chr1_+_87012753 0.86 ENST00000370563.3
CLCA4
chloride channel accessory 4
chr10_+_70847852 0.85 ENST00000242465.3
SRGN
serglycin
chr1_+_145293371 0.85 ENST00000342960.5
NBPF10
neuroblastoma breakpoint family, member 10
chr10_+_103912137 0.83 ENST00000603742.1
ENST00000488254.2
ENST00000461421.1
ENST00000476468.1
ENST00000370007.5
NOLC1
nucleolar and coiled-body phosphoprotein 1
chr15_+_89631647 0.82 ENST00000569550.1
ENST00000565066.1
ENST00000565973.1
ABHD2
abhydrolase domain containing 2
chr11_-_104905840 0.81 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
CASP1
caspase 1, apoptosis-related cysteine peptidase
chr4_+_36283213 0.80 ENST00000357504.3
DTHD1
death domain containing 1
chr7_-_97501706 0.77 ENST00000455086.1
ENST00000453600.1
ASNS
asparagine synthetase (glutamine-hydrolyzing)
chr8_+_120079478 0.76 ENST00000332843.2
COLEC10
collectin sub-family member 10 (C-type lectin)
chr3_-_107941209 0.75 ENST00000492106.1
IFT57
intraflagellar transport 57 homolog (Chlamydomonas)
chr4_-_23735183 0.73 ENST00000507666.1
RP11-380P13.2
RP11-380P13.2
chr11_-_62609281 0.71 ENST00000525239.1
ENST00000538098.2
WDR74
WD repeat domain 74
chr7_-_142176790 0.71 ENST00000390369.2
TRBV7-4
T cell receptor beta variable 7-4 (gene/pseudogene)
chr12_-_56236690 0.71 ENST00000322569.4
MMP19
matrix metallopeptidase 19
chr2_+_185463093 0.70 ENST00000302277.6
ZNF804A
zinc finger protein 804A
chr8_+_31496809 0.69 ENST00000518104.1
ENST00000519301.1
NRG1
neuregulin 1
chr6_+_135502501 0.68 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr4_+_120860695 0.68 ENST00000505122.2
RP11-700N1.1
RP11-700N1.1
chr17_-_39216344 0.68 ENST00000391418.2
KRTAP2-3
keratin associated protein 2-3
chr7_-_137686791 0.68 ENST00000452463.1
ENST00000330387.6
ENST00000456390.1
CREB3L2
cAMP responsive element binding protein 3-like 2
chr9_-_117853297 0.66 ENST00000542877.1
ENST00000537320.1
ENST00000341037.4
TNC
tenascin C
chr10_+_103911926 0.65 ENST00000605788.1
ENST00000405356.1
NOLC1
nucleolar and coiled-body phosphoprotein 1
chr17_-_60883993 0.65 ENST00000583803.1
ENST00000456609.2
MARCH10
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr11_-_47870091 0.64 ENST00000526870.1
NUP160
nucleoporin 160kDa
chr2_+_190306159 0.64 ENST00000314761.4
WDR75
WD repeat domain 75
chr17_-_34257731 0.63 ENST00000431884.2
ENST00000425909.3
ENST00000394528.3
ENST00000430160.2
RDM1
RAD52 motif 1
chr15_-_72523924 0.63 ENST00000566809.1
ENST00000567087.1
ENST00000569050.1
ENST00000568883.1
PKM
pyruvate kinase, muscle
chr17_+_7461849 0.62 ENST00000338784.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr2_+_161993412 0.62 ENST00000259075.2
ENST00000432002.1
TANK
TRAF family member-associated NFKB activator
chr6_+_135502408 0.61 ENST00000341911.5
ENST00000442647.2
ENST00000316528.8
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr8_-_20040638 0.61 ENST00000519026.1
ENST00000276373.5
ENST00000440926.1
ENST00000437980.1
SLC18A1
solute carrier family 18 (vesicular monoamine transporter), member 1
chr12_-_50294033 0.61 ENST00000552669.1
FAIM2
Fas apoptotic inhibitory molecule 2
chr9_-_134955246 0.61 ENST00000357028.2
ENST00000474263.1
ENST00000292035.5
MED27
mediator complex subunit 27
chr20_+_4152356 0.61 ENST00000379460.2
SMOX
spermine oxidase
chr14_+_101123580 0.60 ENST00000556697.1
ENST00000360899.2
ENST00000553623.1
LINC00523
long intergenic non-protein coding RNA 523
chr13_+_27844464 0.59 ENST00000241463.4
RASL11A
RAS-like, family 11, member A
chr6_+_43739697 0.59 ENST00000230480.6
VEGFA
vascular endothelial growth factor A
chr15_-_89010607 0.58 ENST00000312475.4
MRPL46
mitochondrial ribosomal protein L46
chr2_-_3606206 0.57 ENST00000315212.3
RNASEH1
ribonuclease H1
chr11_+_64323156 0.56 ENST00000377585.3
SLC22A11
solute carrier family 22 (organic anion/urate transporter), member 11
chr7_-_76255444 0.55 ENST00000454397.1
POMZP3
POM121 and ZP3 fusion
chr22_-_32651326 0.55 ENST00000266086.4
SLC5A4
solute carrier family 5 (glucose activated ion channel), member 4
chr19_+_40476912 0.55 ENST00000157812.2
PSMC4
proteasome (prosome, macropain) 26S subunit, ATPase, 4
chr12_-_10251539 0.54 ENST00000420265.2
CLEC1A
C-type lectin domain family 1, member A
chr7_+_107531580 0.54 ENST00000537148.1
ENST00000440410.1
ENST00000437604.2
DLD
dihydrolipoamide dehydrogenase
chr17_-_34257771 0.54 ENST00000394529.3
ENST00000293273.6
RDM1
RAD52 motif 1
chr10_-_21435488 0.54 ENST00000534331.1
ENST00000529198.1
ENST00000377118.4
C10orf113
chromosome 10 open reading frame 113
chr4_+_156680153 0.54 ENST00000502959.1
ENST00000505764.1
ENST00000507146.1
ENST00000264424.8
ENST00000503520.1
GUCY1B3
guanylate cyclase 1, soluble, beta 3
chr1_-_153514241 0.53 ENST00000368718.1
ENST00000359215.1
S100A5
S100 calcium binding protein A5
chr6_+_135502466 0.52 ENST00000367814.4
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr12_-_10251603 0.52 ENST00000457018.2
CLEC1A
C-type lectin domain family 1, member A
chr17_+_7462103 0.52 ENST00000396545.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr3_-_161090660 0.51 ENST00000359175.4
SPTSSB
serine palmitoyltransferase, small subunit B
chr1_+_100818156 0.51 ENST00000336454.3
CDC14A
cell division cycle 14A
chr18_-_10748498 0.51 ENST00000579949.1
PIEZO2
piezo-type mechanosensitive ion channel component 2
chr20_-_42355629 0.50 ENST00000373003.1
GTSF1L
gametocyte specific factor 1-like
chr12_+_57828521 0.50 ENST00000309668.2
INHBC
inhibin, beta C
chr1_-_11036272 0.50 ENST00000520253.1
C1orf127
chromosome 1 open reading frame 127
chr3_-_150264272 0.49 ENST00000491660.1
ENST00000487153.1
ENST00000239944.2
SERP1
stress-associated endoplasmic reticulum protein 1
chr2_+_79252822 0.49 ENST00000272324.5
REG3G
regenerating islet-derived 3 gamma
chr9_-_128246769 0.49 ENST00000444226.1
MAPKAP1
mitogen-activated protein kinase associated protein 1
chr5_+_69321074 0.48 ENST00000380751.5
ENST00000380750.3
ENST00000503931.1
ENST00000506542.1
SERF1B
small EDRK-rich factor 1B (centromeric)
chr17_+_7462031 0.48 ENST00000380535.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr17_+_7461781 0.48 ENST00000349228.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr15_-_43785274 0.48 ENST00000413546.1
TP53BP1
tumor protein p53 binding protein 1
chr3_+_121796697 0.48 ENST00000482356.1
ENST00000393627.2
CD86
CD86 molecule
chr6_+_30130969 0.48 ENST00000376694.4
TRIM15
tripartite motif containing 15
chr19_+_35630926 0.47 ENST00000588081.1
ENST00000589121.1
FXYD1
FXYD domain containing ion transport regulator 1
chr12_-_10251576 0.47 ENST00000315330.4
CLEC1A
C-type lectin domain family 1, member A
chr7_+_7606497 0.46 ENST00000340080.4
ENST00000405785.1
ENST00000433635.1
MIOS
missing oocyte, meiosis regulator, homolog (Drosophila)
chr3_-_110612323 0.46 ENST00000383686.2
RP11-553A10.1
Uncharacterized protein
chr6_+_131571535 0.46 ENST00000474850.2
AKAP7
A kinase (PRKA) anchor protein 7
chr2_+_90259593 0.46 ENST00000471857.1
IGKV1D-8
immunoglobulin kappa variable 1D-8
chr17_+_7461613 0.46 ENST00000438470.1
ENST00000436057.1
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr3_-_110612059 0.45 ENST00000485473.1
RP11-553A10.1
Uncharacterized protein
chr15_+_89631381 0.45 ENST00000352732.5
ABHD2
abhydrolase domain containing 2
chr4_+_156680143 0.45 ENST00000505154.1
GUCY1B3
guanylate cyclase 1, soluble, beta 3
chr6_-_9939552 0.44 ENST00000460363.2
OFCC1
orofacial cleft 1 candidate 1
chr20_+_2795626 0.43 ENST00000603872.1
ENST00000380589.4
C20orf141
chromosome 20 open reading frame 141
chr2_+_79252804 0.43 ENST00000393897.2
REG3G
regenerating islet-derived 3 gamma
chr2_+_85661918 0.42 ENST00000340326.2
SH2D6
SH2 domain containing 6
chr6_+_31126291 0.41 ENST00000376257.3
ENST00000376255.4
TCF19
transcription factor 19
chr6_+_160542870 0.41 ENST00000324965.4
ENST00000457470.2
SLC22A1
solute carrier family 22 (organic cation transporter), member 1
chr10_+_24738355 0.39 ENST00000307544.6
KIAA1217
KIAA1217
chr1_+_197382957 0.39 ENST00000367397.1
CRB1
crumbs homolog 1 (Drosophila)
chr1_+_180165672 0.38 ENST00000443059.1
QSOX1
quiescin Q6 sulfhydryl oxidase 1
chr16_+_57496299 0.37 ENST00000219252.5
POLR2C
polymerase (RNA) II (DNA directed) polypeptide C, 33kDa
chr6_+_160542821 0.37 ENST00000366963.4
SLC22A1
solute carrier family 22 (organic cation transporter), member 1
chr1_+_203734296 0.37 ENST00000442561.2
ENST00000367217.5
LAX1
lymphocyte transmembrane adaptor 1
chr12_-_53074182 0.37 ENST00000252244.3
KRT1
keratin 1
chr9_+_125376948 0.37 ENST00000297913.2
OR1Q1
olfactory receptor, family 1, subfamily Q, member 1
chr10_+_96443378 0.36 ENST00000285979.6
CYP2C18
cytochrome P450, family 2, subfamily C, polypeptide 18
chr4_-_168155169 0.35 ENST00000534949.1
ENST00000535728.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr22_-_44258360 0.35 ENST00000330884.4
ENST00000249130.5
SULT4A1
sulfotransferase family 4A, member 1
chr17_+_7461580 0.34 ENST00000483039.1
ENST00000396542.1
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr19_-_51537982 0.34 ENST00000525263.1
KLK12
kallikrein-related peptidase 12
chr4_-_46911223 0.33 ENST00000396533.1
COX7B2
cytochrome c oxidase subunit VIIb2
chr6_-_32784687 0.33 ENST00000447394.1
ENST00000438763.2
HLA-DOB
major histocompatibility complex, class II, DO beta
chr21_-_35883541 0.33 ENST00000399284.1
KCNE1
potassium voltage-gated channel, Isk-related family, member 1
chr3_-_8811288 0.32 ENST00000316793.3
ENST00000431493.1
OXTR
oxytocin receptor
chr19_+_50169081 0.31 ENST00000246784.3
BCL2L12
BCL2-like 12 (proline rich)
chr19_-_40228657 0.30 ENST00000221804.4
CLC
Charcot-Leyden crystal galectin
chr6_+_24126350 0.30 ENST00000378491.4
ENST00000378478.1
ENST00000378477.2
NRSN1
neurensin 1
chr12_-_6961050 0.30 ENST00000538862.2
CDCA3
cell division cycle associated 3
chr12_-_18890940 0.30 ENST00000543242.1
ENST00000539072.1
ENST00000541966.1
ENST00000266505.7
ENST00000447925.2
ENST00000435379.1
PLCZ1
phospholipase C, zeta 1
chr3_-_107941230 0.29 ENST00000264538.3
IFT57
intraflagellar transport 57 homolog (Chlamydomonas)
chr2_-_26864228 0.29 ENST00000288861.4
CIB4
calcium and integrin binding family member 4
chr19_+_18794470 0.29 ENST00000321949.8
ENST00000338797.6
CRTC1
CREB regulated transcription coactivator 1
chr12_-_86650045 0.29 ENST00000604798.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr17_-_33760269 0.28 ENST00000452764.3
SLFN12
schlafen family member 12
chrX_-_23926004 0.28 ENST00000379226.4
ENST00000379220.3
APOO
apolipoprotein O
chr19_-_52133588 0.28 ENST00000570106.2
SIGLEC5
sialic acid binding Ig-like lectin 5
chr3_+_44754126 0.27 ENST00000449836.1
ENST00000436624.2
ENST00000296091.4
ENST00000411443.1
ZNF502
zinc finger protein 502
chr7_+_129984630 0.27 ENST00000355388.3
ENST00000497503.1
ENST00000463587.1
ENST00000461828.1
ENST00000494311.1
ENST00000466363.2
ENST00000485477.1
ENST00000431780.2
ENST00000474905.1
CPA5
carboxypeptidase A5
chr2_-_179672142 0.27 ENST00000342992.6
ENST00000360870.5
ENST00000460472.2
ENST00000589042.1
ENST00000591111.1
ENST00000342175.6
ENST00000359218.5
TTN
titin
chr12_-_57873631 0.26 ENST00000393791.3
ENST00000356411.2
ENST00000552249.1
ARHGAP9
Rho GTPase activating protein 9
chr1_-_21059029 0.25 ENST00000444387.2
ENST00000375031.1
ENST00000518294.1
SH2D5
SH2 domain containing 5
chr15_-_49255632 0.25 ENST00000332408.4
SHC4
SHC (Src homology 2 domain containing) family, member 4
chr1_+_171283331 0.25 ENST00000367749.3
FMO4
flavin containing monooxygenase 4
chr2_+_90192768 0.25 ENST00000390275.2
IGKV1D-13
immunoglobulin kappa variable 1D-13
chr10_+_135340859 0.25 ENST00000252945.3
ENST00000421586.1
ENST00000418356.1
CYP2E1
cytochrome P450, family 2, subfamily E, polypeptide 1
chr11_+_60609537 0.24 ENST00000227520.5
CCDC86
coiled-coil domain containing 86
chr16_-_20367584 0.24 ENST00000570689.1
UMOD
uromodulin
chr15_-_43785303 0.24 ENST00000382039.3
ENST00000450115.2
ENST00000382044.4
TP53BP1
tumor protein p53 binding protein 1
chr19_+_35939154 0.24 ENST00000599180.2
FFAR2
free fatty acid receptor 2
chr10_-_43892668 0.24 ENST00000544000.1
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr1_+_155006300 0.24 ENST00000295542.1
ENST00000392480.1
ENST00000423025.2
ENST00000368419.2
DCST1
DC-STAMP domain containing 1
chr2_-_79313973 0.24 ENST00000454188.1
REG1B
regenerating islet-derived 1 beta
chr19_-_7812446 0.24 ENST00000394173.4
ENST00000301357.8
CD209
CD209 molecule
chr11_+_113185292 0.24 ENST00000429951.1
ENST00000442859.1
ENST00000531164.1
ENST00000529850.1
ENST00000314756.3
ENST00000525965.1
TTC12
tetratricopeptide repeat domain 12
chrY_-_13524717 0.23 ENST00000331172.6
SLC9B1P1
solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1 pseudogene 1
chr8_+_39792474 0.23 ENST00000502986.2
IDO2
indoleamine 2,3-dioxygenase 2
chr17_-_80017856 0.23 ENST00000577574.1
DUS1L
dihydrouridine synthase 1-like (S. cerevisiae)
chr2_+_219524473 0.22 ENST00000439945.1
ENST00000431802.1
BCS1L
BC1 (ubiquinol-cytochrome c reductase) synthesis-like
chr4_+_119809984 0.22 ENST00000307142.4
ENST00000448416.2
ENST00000429713.2
SYNPO2
synaptopodin 2
chr19_-_55791431 0.22 ENST00000593263.1
ENST00000376343.3
HSPBP1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr6_-_31628512 0.22 ENST00000375911.1
C6orf47
chromosome 6 open reading frame 47
chr5_-_133510456 0.22 ENST00000520417.1
SKP1
S-phase kinase-associated protein 1
chr19_+_9361606 0.21 ENST00000456448.1
OR7E24
olfactory receptor, family 7, subfamily E, member 24
chr4_+_75230853 0.21 ENST00000244869.2
EREG
epiregulin
chr1_-_157522260 0.20 ENST00000368191.3
ENST00000361835.3
FCRL5
Fc receptor-like 5
chr15_-_35088340 0.20 ENST00000290378.4
ACTC1
actin, alpha, cardiac muscle 1
chr11_+_67222818 0.20 ENST00000325656.5
CABP4
calcium binding protein 4
chr10_-_104597286 0.20 ENST00000369887.3
CYP17A1
cytochrome P450, family 17, subfamily A, polypeptide 1
chr2_-_37193606 0.20 ENST00000379213.2
ENST00000263918.4
STRN
striatin, calmodulin binding protein
chr21_-_43816052 0.19 ENST00000398405.1
TMPRSS3
transmembrane protease, serine 3
chr8_-_53322303 0.19 ENST00000276480.7
ST18
suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein)
chr5_+_140235469 0.19 ENST00000506939.2
ENST00000307360.5
PCDHA10
protocadherin alpha 10
chr11_+_55594695 0.19 ENST00000378397.1
OR5L2
olfactory receptor, family 5, subfamily L, member 2
chr19_-_55791540 0.19 ENST00000433386.2
HSPBP1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr1_+_171227069 0.19 ENST00000354841.4
FMO1
flavin containing monooxygenase 1
chr1_-_186649543 0.18 ENST00000367468.5
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr4_+_71091786 0.18 ENST00000317987.5
FDCSP
follicular dendritic cell secreted protein
chr19_-_55791563 0.18 ENST00000588971.1
ENST00000255631.5
ENST00000587551.1
HSPBP1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr1_-_27952741 0.18 ENST00000399173.1
FGR
feline Gardner-Rasheed sarcoma viral oncogene homolog
chr19_-_51538118 0.18 ENST00000529888.1
KLK12
kallikrein-related peptidase 12
chr22_+_23029188 0.18 ENST00000390305.2
IGLV3-25
immunoglobulin lambda variable 3-25
chr22_-_37403858 0.17 ENST00000405091.2
TEX33
testis expressed 33
chr11_-_58343319 0.17 ENST00000395074.2
LPXN
leupaxin
chr2_-_29297127 0.17 ENST00000331664.5
C2orf71
chromosome 2 open reading frame 71
chr11_+_60223312 0.17 ENST00000532491.1
ENST00000532073.1
ENST00000534668.1
ENST00000528313.1
ENST00000533306.1
MS4A1
membrane-spanning 4-domains, subfamily A, member 1
chr22_-_37403839 0.17 ENST00000402860.3
ENST00000381821.1
TEX33
testis expressed 33
chr10_+_12391685 0.17 ENST00000378845.1
CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr17_+_6918093 0.17 ENST00000439424.2
C17orf49
chromosome 17 open reading frame 49
chr1_-_157522180 0.16 ENST00000356953.4
ENST00000368188.2
ENST00000368190.3
ENST00000368189.3
FCRL5
Fc receptor-like 5
chr1_-_119682812 0.16 ENST00000537870.1
WARS2
tryptophanyl tRNA synthetase 2, mitochondrial
chr7_-_56160625 0.16 ENST00000446428.1
ENST00000432123.1
ENST00000452681.2
ENST00000537360.1
PHKG1
phosphorylase kinase, gamma 1 (muscle)
chr11_+_27076764 0.15 ENST00000525090.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr1_-_25256368 0.15 ENST00000308873.6
RUNX3
runt-related transcription factor 3

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.6 5.1 GO:0021564 vagus nerve development(GO:0021564)
0.6 1.8 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.5 1.6 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.5 2.7 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.4 2.7 GO:0008218 bioluminescence(GO:0008218)
0.3 1.0 GO:0044278 cell wall disruption in other organism(GO:0044278)
0.3 2.6 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.3 3.1 GO:0042940 D-amino acid transport(GO:0042940)
0.3 7.4 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.3 0.9 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.3 1.5 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.2 2.9 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.2 1.9 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.2 0.2 GO:0042700 luteinizing hormone signaling pathway(GO:0042700)
0.2 0.8 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.2 1.8 GO:0001554 luteolysis(GO:0001554)
0.2 0.6 GO:1903572 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.2 1.7 GO:0070294 renal sodium ion absorption(GO:0070294)
0.2 0.6 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.2 0.8 GO:0070981 L-asparagine biosynthetic process(GO:0070981) L-asparagine metabolic process(GO:0070982)
0.2 0.5 GO:0042097 negative regulation of tolerance induction(GO:0002644) interleukin-4 biosynthetic process(GO:0042097) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.2 1.4 GO:0006857 oligopeptide transport(GO:0006857)
0.1 0.5 GO:0009106 lipoate metabolic process(GO:0009106)
0.1 1.5 GO:0007000 nucleolus organization(GO:0007000)
0.1 0.7 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.1 1.3 GO:0032962 positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.1 1.0 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.1 0.8 GO:0048241 epinephrine transport(GO:0048241)
0.1 0.3 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.1 0.3 GO:0034059 response to anoxia(GO:0034059)
0.1 0.6 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 0.6 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.1 0.6 GO:0046208 spermine catabolic process(GO:0046208)
0.1 0.7 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 0.3 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.1 1.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.6 GO:0035803 egg coat formation(GO:0035803)
0.1 0.5 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.1 0.6 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.1 0.5 GO:0010732 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.1 0.3 GO:0007343 egg activation(GO:0007343)
0.1 0.5 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 0.2 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.3 GO:0046968 peptide antigen transport(GO:0046968)
0.1 0.7 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 0.3 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.1 0.3 GO:0002911 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.0 0.2 GO:0010193 response to ozone(GO:0010193)
0.0 0.2 GO:0072233 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.0 0.1 GO:0031990 mRNA export from nucleus in response to heat stress(GO:0031990)
0.0 0.9 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.1 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.0 1.3 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.6 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.6 GO:0015747 urate transport(GO:0015747)
0.0 0.3 GO:0044789 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 0.2 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 1.0 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.2 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 0.5 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.1 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.1 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.5 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.2 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.0 0.2 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.4 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.0 0.2 GO:0010265 SCF complex assembly(GO:0010265)
0.0 2.4 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 1.0 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.5 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.2 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.1 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.0 0.2 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.1 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.0 0.4 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.3 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.0 0.6 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.2 GO:0042737 drug catabolic process(GO:0042737)
0.0 0.2 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.5 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0046149 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.5 GO:0050974 detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.0 0.5 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.1 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 0.6 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.5 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.2 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.0 0.4 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.2 GO:0006702 androgen biosynthetic process(GO:0006702)
0.0 0.4 GO:0048305 immunoglobulin secretion(GO:0048305)
0.0 0.1 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.2 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.7 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.2 5.1 GO:0005614 interstitial matrix(GO:0005614)
0.2 0.5 GO:0043159 acrosomal matrix(GO:0043159)
0.1 0.8 GO:0072558 NLRP1 inflammasome complex(GO:0072558) protease inhibitor complex(GO:0097179)
0.1 1.3 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 0.6 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.1 0.5 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 0.9 GO:0001673 male germ cell nucleus(GO:0001673)
0.1 6.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.9 GO:0042588 zymogen granule(GO:0042588)
0.0 1.7 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.5 GO:0060091 kinocilium(GO:0060091)
0.0 0.5 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.5 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.2 GO:0042643 actomyosin, actin portion(GO:0042643)
0.0 1.0 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.6 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 1.0 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.3 GO:0061617 MICOS complex(GO:0061617)
0.0 2.6 GO:0015030 Cajal body(GO:0015030)
0.0 0.5 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:1990425 ryanodine receptor complex(GO:1990425)
0.0 0.2 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.3 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.7 GO:0030673 axolemma(GO:0030673)
0.0 0.5 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.7 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)
0.0 1.0 GO:0045095 keratin filament(GO:0045095)
0.0 2.1 GO:0001650 fibrillar center(GO:0001650)
0.0 1.0 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 1.7 GO:0016363 nuclear matrix(GO:0016363)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.7 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.5 7.1 GO:0033691 sialic acid binding(GO:0033691)
0.3 1.4 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.3 1.5 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.2 0.6 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.2 0.6 GO:0052895 norspermine:oxygen oxidoreductase activity(GO:0052894) N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity(GO:0052895)
0.2 0.8 GO:0008513 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.2 0.6 GO:0004743 pyruvate kinase activity(GO:0004743)
0.2 0.8 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.2 1.8 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 1.5 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 1.3 GO:0004969 histamine receptor activity(GO:0004969)
0.1 5.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.7 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.5 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.6 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.2 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.1 0.4 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 1.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 1.3 GO:0005549 odorant binding(GO:0005549)
0.1 0.7 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 1.0 GO:0070492 oligosaccharide binding(GO:0070492)
0.1 0.5 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 0.7 GO:0045545 syndecan binding(GO:0045545)
0.1 0.5 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 0.4 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.6 GO:0032190 acrosin binding(GO:0032190)
0.1 0.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 1.0 GO:0005537 mannose binding(GO:0005537)
0.1 1.4 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.5 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.2 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.6 GO:0031433 telethonin binding(GO:0031433)
0.0 0.2 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.1 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.2 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.8 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.6 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 1.0 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.5 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.3 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.2 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.9 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0019862 IgA binding(GO:0019862)
0.0 0.6 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.1 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.7 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.1 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.9 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.1 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.5 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.3 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.5 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.1 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.0 4.1 GO:0004386 helicase activity(GO:0004386)
0.0 0.4 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 2.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.5 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.0 GO:0045518 interleukin-22 receptor binding(GO:0045518)
0.0 0.6 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 1.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.3 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.3 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.5 GO:0015026 coreceptor activity(GO:0015026)
0.0 1.6 GO:0001653 peptide receptor activity(GO:0001653) G-protein coupled peptide receptor activity(GO:0008528)
0.0 0.3 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.6 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 3.1 ST GAQ PATHWAY G alpha q Pathway
0.1 7.3 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 1.7 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 1.8 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.8 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 1.0 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.5 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 1.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.7 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.8 PID IFNG PATHWAY IFN-gamma pathway
0.0 1.5 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 3.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 PID ATM PATHWAY ATM pathway
0.0 0.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.5 ST JNK MAPK PATHWAY JNK MAPK Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 0.8 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.8 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.7 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 4.0 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.8 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 2.9 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.7 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.7 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 1.3 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 1.0 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 2.3 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.6 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.5 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.3 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.5 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 3.5 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.8 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 1.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 1.8 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production