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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for PBX1

Z-value: 0.50

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Transcription factors associated with PBX1

Gene Symbol Gene ID Gene Info
ENSG00000185630.14 PBX homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PBX1hg19_v2_chr1_+_164528866_1645288770.481.4e-02Click!

Activity profile of PBX1 motif

Sorted Z-values of PBX1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_14308004 1.25 ENST00000493697.1
nuclear factor I/B
chr2_+_12857015 1.12 ENST00000155926.4
tribbles pseudokinase 2
chr2_+_12857043 1.10 ENST00000381465.2
tribbles pseudokinase 2
chr12_+_79258444 1.05 ENST00000261205.4
synaptotagmin I
chrX_+_53123314 0.84 ENST00000605526.1
ENST00000604062.1
ENST00000604369.1
ENST00000366185.2
ENST00000604849.1
long intergenic non-protein coding RNA 1155
chr12_+_79258547 0.78 ENST00000457153.2
synaptotagmin I
chr7_-_120498357 0.73 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
tetraspanin 12
chr12_-_95510743 0.69 ENST00000551521.1
FYVE, RhoGEF and PH domain containing 6
chr19_+_41698927 0.67 ENST00000310054.4
cytochrome P450, family 2, subfamily S, polypeptide 1
chr6_+_27775899 0.60 ENST00000358739.3
histone cluster 1, H2ai
chr4_-_70626430 0.56 ENST00000310613.3
sulfotransferase family, cytosolic, 1B, member 1
chrX_-_63005405 0.56 ENST00000374878.1
ENST00000437457.2
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr12_-_56615693 0.53 ENST00000394013.2
ENST00000345093.4
ENST00000551711.1
ENST00000552656.1
ring finger protein 41
chr10_-_18948156 0.51 ENST00000414939.1
ENST00000449529.1
ENST00000456217.1
ENST00000444660.1
ARL5B antisense RNA 1
chr11_+_95523823 0.48 ENST00000538658.1
centrosomal protein 57kDa
chr2_+_234104079 0.47 ENST00000417661.1
inositol polyphosphate-5-phosphatase, 145kDa
chr3_+_193853927 0.45 ENST00000232424.3
hes family bHLH transcription factor 1
chr22_-_29137771 0.44 ENST00000439200.1
ENST00000405598.1
ENST00000398017.2
ENST00000425190.2
ENST00000348295.3
ENST00000382578.1
ENST00000382565.1
ENST00000382566.1
ENST00000382580.2
ENST00000328354.6
checkpoint kinase 2
chr14_-_74551096 0.41 ENST00000350259.4
aldehyde dehydrogenase 6 family, member A1
chrM_-_14670 0.41 ENST00000361681.2
mitochondrially encoded NADH dehydrogenase 6
chrX_-_50386648 0.40 ENST00000460112.3
shroom family member 4
chrX_-_70474499 0.39 ENST00000353904.2
zinc finger, MYM-type 3
chr14_+_22985251 0.39 ENST00000390510.1
T cell receptor alpha joining 27
chr13_+_97928395 0.37 ENST00000445661.2
muscleblind-like splicing regulator 2
chr19_-_14640005 0.37 ENST00000596853.1
ENST00000596075.1
ENST00000595992.1
ENST00000396969.4
ENST00000601533.1
ENST00000598692.1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr4_+_83956237 0.35 ENST00000264389.2
COP9 signalosome subunit 4
chr11_+_95523621 0.35 ENST00000325542.5
ENST00000325486.5
ENST00000544522.1
ENST00000541365.1
centrosomal protein 57kDa
chr8_+_98788057 0.34 ENST00000517924.1
lysosomal protein transmembrane 4 beta
chr4_+_83956312 0.34 ENST00000509317.1
ENST00000503682.1
ENST00000511653.1
COP9 signalosome subunit 4
chrX_-_70473957 0.34 ENST00000373984.3
ENST00000314425.5
ENST00000373982.1
zinc finger, MYM-type 3
chr15_+_43477455 0.33 ENST00000300213.4
cyclin D-type binding-protein 1
chr5_-_171881362 0.33 ENST00000519643.1
SH3 and PX domains 2B
chr13_-_22033392 0.33 ENST00000320220.9
ENST00000415724.1
ENST00000422251.1
ENST00000382466.3
ENST00000542645.1
ENST00000400590.3
zinc finger, DHHC-type containing 20
chr16_+_69458537 0.32 ENST00000515314.1
ENST00000561792.1
ENST00000568237.1
cytochrome b5 type B (outer mitochondrial membrane)
chr17_+_45973516 0.32 ENST00000376741.4
Sp2 transcription factor
chr4_-_152147579 0.32 ENST00000304527.4
ENST00000455740.1
ENST00000424281.1
ENST00000409598.4
SH3 domain containing 19
chr16_+_15596123 0.32 ENST00000452191.2
chromosome 16 open reading frame 45
chr5_-_42825983 0.31 ENST00000506577.1
selenoprotein P, plasma, 1
chr10_+_124320156 0.30 ENST00000338354.3
ENST00000344338.3
ENST00000330163.4
ENST00000368909.3
ENST00000368955.3
ENST00000368956.2
deleted in malignant brain tumors 1
chr8_+_98788003 0.30 ENST00000521545.2
lysosomal protein transmembrane 4 beta
chr7_+_23637763 0.30 ENST00000410069.1
coiled-coil domain containing 126
chr10_+_124320195 0.28 ENST00000359586.6
deleted in malignant brain tumors 1
chr5_-_43313574 0.28 ENST00000325110.6
ENST00000433297.2
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr5_+_159656437 0.27 ENST00000402432.3
fatty acid binding protein 6, ileal
chr3_-_169587621 0.27 ENST00000523069.1
ENST00000316428.5
ENST00000264676.5
leucine rich repeat containing 31
chr11_+_31531291 0.27 ENST00000350638.5
ENST00000379163.5
ENST00000395934.2
elongator acetyltransferase complex subunit 4
chr22_-_26961328 0.27 ENST00000398110.2
tyrosylprotein sulfotransferase 2
chr11_-_31531121 0.27 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr12_+_101988627 0.26 ENST00000547405.1
ENST00000452455.2
ENST00000441232.1
ENST00000360610.2
ENST00000392934.3
ENST00000547509.1
ENST00000361685.2
ENST00000549145.1
ENST00000553190.1
myosin binding protein C, slow type
chr17_+_7758374 0.26 ENST00000301599.6
ENST00000574668.1
transmembrane protein 88
chr17_-_27038063 0.25 ENST00000439862.3
protein interacting with cyclin A1
chr19_+_35417939 0.25 ENST00000601142.1
ENST00000426813.2
zinc finger protein 30
chr11_+_22689648 0.25 ENST00000278187.3
growth arrest-specific 2
chr6_-_51952418 0.25 ENST00000371117.3
polycystic kidney and hepatic disease 1 (autosomal recessive)
chr6_+_151561085 0.24 ENST00000402676.2
A kinase (PRKA) anchor protein 12
chr17_+_58755184 0.24 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
breast carcinoma amplified sequence 3
chr11_-_2162162 0.24 ENST00000381389.1
insulin-like growth factor 2 (somatomedin A)
chr17_+_75181292 0.24 ENST00000431431.2
SEC14-like 1 (S. cerevisiae)
chrX_-_102757802 0.24 ENST00000372633.1
RAB40A, member RAS oncogene family
chr6_-_36725157 0.23 ENST00000393189.2
copine V
chr2_-_200323414 0.23 ENST00000443023.1
SATB homeobox 2
chr16_+_19079215 0.23 ENST00000544894.2
ENST00000561858.1
coenzyme Q7 homolog, ubiquinone (yeast)
chr14_-_74551172 0.22 ENST00000553458.1
aldehyde dehydrogenase 6 family, member A1
chr3_-_129158850 0.22 ENST00000503197.1
ENST00000249910.1
ENST00000429544.2
ENST00000507208.1
methyl-CpG binding domain protein 4
chr16_-_49890016 0.22 ENST00000563137.2
zinc finger protein 423
chr2_+_169926047 0.22 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
dehydrogenase/reductase (SDR family) member 9
chr16_+_19078960 0.22 ENST00000568985.1
ENST00000566110.1
coenzyme Q7 homolog, ubiquinone (yeast)
chr3_+_111451321 0.22 ENST00000393923.3
pleckstrin homology-like domain, family B, member 2
chr3_-_129158676 0.21 ENST00000393278.2
methyl-CpG binding domain protein 4
chr12_+_101988774 0.21 ENST00000545503.2
ENST00000536007.1
ENST00000541119.1
ENST00000361466.2
ENST00000551300.1
ENST00000550270.1
myosin binding protein C, slow type
chr2_-_200322723 0.21 ENST00000417098.1
SATB homeobox 2
chr2_-_89247338 0.21 ENST00000496168.1
immunoglobulin kappa variable 1-5
chr14_+_50234309 0.20 ENST00000298307.5
kelch domain containing 2
chr12_+_12870055 0.20 ENST00000228872.4
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
chr17_-_26694979 0.20 ENST00000438614.1
vitronectin
chr13_+_57721622 0.20 ENST00000377930.1
proline rich 20B
chr19_-_58400372 0.20 ENST00000597832.1
ENST00000435989.2
zinc finger protein 814
chr3_+_148508845 0.19 ENST00000491148.1
carboxypeptidase B1 (tissue)
chr17_-_26695013 0.19 ENST00000555059.2
Homeobox protein SEBOX
chr16_+_50099852 0.19 ENST00000299192.7
ENST00000285767.4
HEAT repeat containing 3
chr18_-_59854203 0.19 ENST00000589339.1
ENST00000357637.5
ENST00000585458.1
ENST00000400334.3
ENST00000587134.1
ENST00000585923.1
ENST00000590765.1
ENST00000589720.1
ENST00000588571.1
ENST00000585344.1
phosphatidylinositol glycan anchor biosynthesis, class N
chr1_-_115323245 0.19 ENST00000060969.5
ENST00000369528.5
suppressor of IKBKE 1
chr12_-_15104040 0.19 ENST00000541644.1
ENST00000545895.1
Rho GDP dissociation inhibitor (GDI) beta
chr5_+_43603229 0.18 ENST00000344920.4
ENST00000512996.2
nicotinamide nucleotide transhydrogenase
chr2_+_234600253 0.18 ENST00000373424.1
ENST00000441351.1
UDP glucuronosyltransferase 1 family, polypeptide A6
chrX_-_70474377 0.18 ENST00000373978.1
ENST00000373981.1
zinc finger, MYM-type 3
chr10_+_5488564 0.18 ENST00000449083.1
ENST00000380359.3
neuroepithelial cell transforming 1
chr3_+_159557637 0.17 ENST00000445224.2
schwannomin interacting protein 1
chr17_-_39296739 0.17 ENST00000345847.4
keratin associated protein 4-6
chr7_+_80275953 0.16 ENST00000538969.1
ENST00000544133.1
ENST00000433696.2
CD36 molecule (thrombospondin receptor)
chr14_+_23938891 0.16 ENST00000408901.3
ENST00000397154.3
ENST00000555128.1
neuroguidin, EIF4E binding protein
chr14_+_104182105 0.16 ENST00000311141.2
zinc finger, FYVE domain containing 21
chr16_-_88729473 0.16 ENST00000301012.3
ENST00000569177.1
mevalonate (diphospho) decarboxylase
chr16_+_19078911 0.16 ENST00000321998.5
coenzyme Q7 homolog, ubiquinone (yeast)
chr2_-_27886460 0.16 ENST00000404798.2
ENST00000405491.1
ENST00000464789.2
ENST00000406540.1
suppressor of Ty 7 (S. cerevisiae)-like
chr7_+_80275752 0.15 ENST00000419819.2
CD36 molecule (thrombospondin receptor)
chr5_-_94417339 0.15 ENST00000429576.2
ENST00000508509.1
ENST00000510732.1
multiple C2 domains, transmembrane 1
chr11_-_104035088 0.15 ENST00000302251.5
platelet derived growth factor D
chr17_-_38821373 0.15 ENST00000394052.3
keratin 222
chr2_+_27886330 0.14 ENST00000326019.6
solute carrier family 4 (anion exchanger), member 1, adaptor protein
chr14_+_104182061 0.14 ENST00000216602.6
zinc finger, FYVE domain containing 21
chr11_-_34938039 0.14 ENST00000395787.3
APAF1 interacting protein
chr11_+_114166536 0.14 ENST00000299964.3
nicotinamide N-methyltransferase
chr5_+_140213815 0.14 ENST00000525929.1
ENST00000378125.3
protocadherin alpha 7
chr16_+_69221028 0.14 ENST00000336278.4
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr17_+_8191815 0.14 ENST00000226105.6
ENST00000407006.4
ENST00000580434.1
ENST00000439238.3
RAN guanine nucleotide release factor
chr2_-_27886676 0.14 ENST00000337768.5
suppressor of Ty 7 (S. cerevisiae)-like
chr21_-_35014027 0.14 ENST00000399442.1
ENST00000413017.2
ENST00000445393.1
ENST00000417979.1
ENST00000426935.1
ENST00000381540.3
ENST00000361534.2
ENST00000381554.3
crystallin, zeta (quinone reductase)-like 1
chr12_+_123944070 0.13 ENST00000412157.2
small nuclear ribonucleoprotein 35kDa (U11/U12)
chr10_-_101190202 0.13 ENST00000543866.1
ENST00000370508.5
glutamic-oxaloacetic transaminase 1, soluble
chr3_-_149510553 0.13 ENST00000462519.2
ENST00000446160.1
ENST00000383050.3
ankyrin repeat and ubiquitin domain containing 1
chr16_-_29499154 0.13 ENST00000354563.5
Uncharacterized protein
chr5_-_94417314 0.13 ENST00000505208.1
multiple C2 domains, transmembrane 1
chr12_-_102455846 0.13 ENST00000545679.1
coiled-coil domain containing 53
chr22_+_35695793 0.13 ENST00000456128.1
ENST00000449058.2
ENST00000411850.1
ENST00000425375.1
ENST00000436462.2
ENST00000382034.5
target of myb1 (chicken)
chr12_-_102455902 0.13 ENST00000240079.6
coiled-coil domain containing 53
chr7_-_112430427 0.13 ENST00000449743.1
ENST00000441474.1
ENST00000454074.1
ENST00000447395.1
transmembrane protein 168
chr11_+_844406 0.12 ENST00000397404.1
tetraspanin 4
chr3_+_52570610 0.12 ENST00000307106.3
ENST00000477703.1
ENST00000476842.1
small integral membrane protein 4
chr3_+_157827841 0.12 ENST00000295930.3
ENST00000471994.1
ENST00000464171.1
ENST00000312179.6
ENST00000475278.2
arginine/serine-rich coiled-coil 1
chr14_+_24583836 0.12 ENST00000559115.1
ENST00000558215.1
ENST00000557810.1
ENST00000561375.1
ENST00000446197.3
ENST00000559796.1
ENST00000560713.1
ENST00000560901.1
ENST00000559382.1
DDB1 and CUL4 associated factor 11
chr16_-_20702578 0.12 ENST00000307493.4
ENST00000219151.4
acyl-CoA synthetase medium-chain family member 1
chr6_+_83777374 0.11 ENST00000349129.2
ENST00000237163.5
ENST00000536812.1
dopey family member 1
chr2_+_181845298 0.10 ENST00000410062.4
ubiquitin-conjugating enzyme E2E 3
chr9_-_88356789 0.10 ENST00000357081.3
ENST00000376081.4
ENST00000337006.4
ENST00000376109.3
ATP/GTP binding protein 1
chr6_+_36839616 0.10 ENST00000359359.2
ENST00000510325.2
chromosome 6 open reading frame 89
chr6_+_151561506 0.10 ENST00000253332.1
A kinase (PRKA) anchor protein 12
chr15_+_44069276 0.10 ENST00000381359.1
small EDRK-rich factor 2
chr1_-_146068184 0.10 ENST00000604894.1
ENST00000369323.3
ENST00000479926.2
neuroblastoma breakpoint family, member 11
chr6_+_167704838 0.10 ENST00000366829.2
unc-93 homolog A (C. elegans)
chr1_-_147610081 0.10 ENST00000369226.3
neuroblastoma breakpoint family, member 24
chr6_-_51952367 0.09 ENST00000340994.4
polycystic kidney and hepatic disease 1 (autosomal recessive)
chr4_+_187148556 0.09 ENST00000264690.6
ENST00000446598.2
ENST00000414291.1
ENST00000513864.1
kallikrein B, plasma (Fletcher factor) 1
chr1_+_226250379 0.09 ENST00000366815.3
ENST00000366814.3
H3 histone, family 3A
chr2_+_201997676 0.09 ENST00000462763.1
ENST00000479953.2
CASP8 and FADD-like apoptosis regulator
chr3_+_159570722 0.09 ENST00000482804.1
schwannomin interacting protein 1
chr5_+_43602750 0.09 ENST00000505678.2
ENST00000512422.1
ENST00000264663.5
nicotinamide nucleotide transhydrogenase
chr2_+_264913 0.09 ENST00000439645.2
ENST00000405233.1
acid phosphatase 1, soluble
chr2_+_20646824 0.09 ENST00000272233.4
ras homolog family member B
chr15_-_37393406 0.09 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
Meis homeobox 2
chrX_+_1734051 0.09 ENST00000381229.4
ENST00000381233.3
acetylserotonin O-methyltransferase
chr2_-_96971232 0.09 ENST00000323853.5
small nuclear ribonucleoprotein 200kDa (U5)
chr9_-_32573130 0.08 ENST00000350021.2
ENST00000379847.3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa
chr19_-_51141196 0.08 ENST00000338916.4
synaptotagmin III
chr18_+_29598335 0.08 ENST00000217740.3
ring finger protein 125, E3 ubiquitin protein ligase
chr17_+_4853442 0.08 ENST00000522301.1
enolase 3 (beta, muscle)
chr7_-_112430647 0.08 ENST00000312814.6
transmembrane protein 168
chr19_+_58341656 0.08 ENST00000442832.4
ENST00000594901.1
zinc finger protein 587B
chr14_+_50065459 0.08 ENST00000318317.4
leucine rich repeat protein 1
chr1_-_13673511 0.08 ENST00000344998.3
ENST00000334600.6
PRAME family member 14
chrX_+_120181457 0.08 ENST00000328078.1
glutamate dehydrogenase 2
chr11_+_44117260 0.08 ENST00000358681.4
exostosin glycosyltransferase 2
chr22_+_29138013 0.07 ENST00000216027.3
ENST00000398941.2
HscB mitochondrial iron-sulfur cluster co-chaperone
chr16_+_55512742 0.07 ENST00000568715.1
ENST00000219070.4
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr4_-_38784592 0.07 ENST00000502321.1
toll-like receptor 10
chr2_+_113033164 0.07 ENST00000409871.1
ENST00000343936.4
zinc finger CCCH-type containing 6
chr14_+_50065376 0.07 ENST00000298288.6
leucine rich repeat protein 1
chr7_-_77325545 0.07 ENST00000447009.1
ENST00000416650.1
ENST00000440088.1
ENST00000430801.1
ENST00000398043.2
RSBN1L antisense RNA 1
chr3_-_143567262 0.07 ENST00000474151.1
ENST00000316549.6
solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
chrX_+_119737806 0.07 ENST00000371317.5
malignant T cell amplified sequence 1
chr14_-_36789783 0.07 ENST00000605579.1
ENST00000604336.1
ENST00000359527.7
ENST00000603139.1
ENST00000318473.7
MAP3K12 binding inhibitory protein 1
chr19_-_33360647 0.07 ENST00000590341.1
ENST00000587772.1
ENST00000023064.4
solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
chr5_-_86708670 0.07 ENST00000504878.1
cyclin H
chr14_-_104181771 0.07 ENST00000554913.1
ENST00000554974.1
ENST00000553361.1
ENST00000555055.1
ENST00000555964.1
ENST00000556682.1
ENST00000445556.1
ENST00000553332.1
ENST00000352127.7
X-ray repair complementing defective repair in Chinese hamster cells 3
chrM_+_4431 0.07 ENST00000361453.3
mitochondrially encoded NADH dehydrogenase 2
chr5_-_86708833 0.06 ENST00000256897.4
cyclin H
chr19_+_12203069 0.06 ENST00000430298.2
ENST00000339302.4
zinc finger family member 788
Zinc finger protein 788
chr17_+_73663470 0.06 ENST00000583536.1
SAP30 binding protein
chr15_-_54025300 0.06 ENST00000559418.1
WD repeat domain 72
chr2_-_158182410 0.06 ENST00000419116.2
ENST00000410096.1
ermin, ERM-like protein
chr12_+_56401268 0.06 ENST00000262032.5
IKAROS family zinc finger 4 (Eos)
chr5_-_132073111 0.06 ENST00000403231.1
kinesin family member 3A
chr11_-_34937858 0.06 ENST00000278359.5
APAF1 interacting protein
chr7_-_102184083 0.06 ENST00000379357.5
polymerase (RNA) II (DNA directed) polypeptide J3
chr6_+_26124373 0.06 ENST00000377791.2
ENST00000602637.1
histone cluster 1, H2ac
chr10_+_114709999 0.06 ENST00000355995.4
ENST00000545257.1
ENST00000543371.1
ENST00000536810.1
ENST00000355717.4
ENST00000538897.1
ENST00000534894.1
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr1_-_146054494 0.06 ENST00000401009.2
neuroblastoma breakpoint family, member 11
chr12_+_81471816 0.06 ENST00000261206.3
acyl-CoA synthetase short-chain family member 3
chr19_+_14640372 0.06 ENST00000215567.5
ENST00000598298.1
ENST00000596073.1
ENST00000600083.1
ENST00000436007.2
trans-2,3-enoyl-CoA reductase
chr3_-_187388173 0.05 ENST00000287641.3
somatostatin
chr8_-_91095099 0.05 ENST00000265431.3
calbindin 1, 28kDa
chr19_-_58400148 0.05 ENST00000595048.1
ENST00000600634.1
ENST00000595295.1
ENST00000596604.1
ENST00000597342.1
ENST00000597807.1
zinc finger protein 814
chr9_-_6015607 0.05 ENST00000259569.5
RAN binding protein 6
chr22_-_30866564 0.05 ENST00000435069.1
ENST00000415957.2
ENST00000540910.1
SEC14-like 3 (S. cerevisiae)
chrX_+_55649833 0.05 ENST00000339140.3
forkhead box R2
chr4_+_56815102 0.05 ENST00000257287.4
centrosomal protein 135kDa
chr2_+_233897382 0.05 ENST00000233840.3
sialidase 2 (cytosolic sialidase)
chr11_+_44117099 0.05 ENST00000533608.1
exostosin glycosyltransferase 2
chr17_+_58018269 0.05 ENST00000591035.1
Uncharacterized protein
chr5_+_140207536 0.05 ENST00000529310.1
ENST00000527624.1
protocadherin alpha 6
chr1_+_158801095 0.05 ENST00000368141.4
myeloid cell nuclear differentiation antigen
chr2_+_79412357 0.05 ENST00000466387.1
catenin (cadherin-associated protein), alpha 2
chr5_+_68513622 0.05 ENST00000512880.1
ENST00000602380.1
mitochondrial ribosomal protein S36
chr3_+_63638339 0.05 ENST00000343837.3
ENST00000469440.1
sentan, cilia apical structure protein
chr5_-_133702761 0.05 ENST00000521118.1
ENST00000265334.4
ENST00000435211.1
cyclin-dependent kinase-like 3
chr6_-_26199471 0.05 ENST00000341023.1
histone cluster 1, H2ad
chr2_+_62132800 0.05 ENST00000538736.1
copper metabolism (Murr1) domain containing 1
chr1_-_54405773 0.05 ENST00000371376.1
heat shock protein family B (small), member 11
chr8_+_7801144 0.04 ENST00000443676.1
zinc finger protein 705B
chr19_-_39881777 0.04 ENST00000595564.1
ENST00000221265.3
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)

Network of associatons between targets according to the STRING database.

First level regulatory network of PBX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.4 2.2 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.2 1.3 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.2 0.6 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.2 0.5 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.2 0.5 GO:0042668 trochlear nerve development(GO:0021558) auditory receptor cell fate determination(GO:0042668) negative regulation of auditory receptor cell differentiation(GO:0045608) regulation of timing of neuron differentiation(GO:0060164) negative regulation of pro-B cell differentiation(GO:2000974)
0.1 0.4 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.3 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.1 0.3 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.1 0.5 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.1 0.6 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.3 GO:0006740 NADPH regeneration(GO:0006740)
0.1 0.2 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.4 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.1 GO:2000439 positive regulation of monocyte extravasation(GO:2000439)
0.0 0.1 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.0 0.3 GO:0055096 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533)
0.0 0.7 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.1 GO:0018874 benzoate metabolic process(GO:0018874)
0.0 0.3 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.3 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.1 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.1 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.0 0.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.3 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.1 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.1 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.0 0.2 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.5 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.2 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.4 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.4 GO:0045008 depyrimidination(GO:0045008)
0.0 0.3 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.6 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.2 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.7 GO:0009812 flavonoid metabolic process(GO:0009812)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.1 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.0 0.8 GO:0010842 retina layer formation(GO:0010842)
0.0 0.2 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.8 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509) pyroptosis(GO:0070269)
0.0 0.5 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.3 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0007231 osmosensory signaling pathway(GO:0007231)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.0 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.0 0.1 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.2 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.1 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.1 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.0 0.1 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.2 GO:0051451 myoblast migration(GO:0051451)
0.0 0.1 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 0.3 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 1.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.6 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.1 GO:0070985 TFIIK complex(GO:0070985)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.1 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.3 GO:0030914 STAGA complex(GO:0030914)
0.0 0.5 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.9 GO:0016460 myosin II complex(GO:0016460)
0.0 0.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.2 GO:0045180 basal cortex(GO:0045180)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.8 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.7 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 2.2 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 0.3 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 0.3 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 0.4 GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.1 0.5 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1 0.7 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 0.2 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 0.3 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.3 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0080130 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) phosphatidylserine decarboxylase activity(GO:0004609) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.5 GO:0031386 protein tag(GO:0031386)
0.0 0.3 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.0 0.2 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.1 GO:0030760 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.0 0.1 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.0 0.6 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.8 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.5 GO:0031432 titin binding(GO:0031432)
0.0 0.5 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.2 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.5 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.1 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.4 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.8 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 1.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.5 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 1.3 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.4 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.4 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.5 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.2 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.2 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.4 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development