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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for PBX3

Z-value: 1.27

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Transcription factors associated with PBX3

Gene Symbol Gene ID Gene Info
PBX3
ENSG00000167081.12 PBX homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PBX3hg19_v2_chr9_+_128509624_1285096580.545.4e-03Click!

Activity profile of PBX3 motif

Sorted Z-values of PBX3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_100111580 6.50 ENST00000605497.1
PALMD
palmdelphin
chr1_+_100111479 6.28 ENST00000263174.4
PALMD
palmdelphin
chr16_-_30032610 6.01 ENST00000574405.1
DOC2A
double C2-like domains, alpha
chr3_+_193853927 4.08 ENST00000232424.3
HES1
hes family bHLH transcription factor 1
chr4_-_149363662 3.79 ENST00000355292.3
ENST00000358102.3
NR3C2
nuclear receptor subfamily 3, group C, member 2
chr3_-_148804275 3.71 ENST00000392912.2
ENST00000465259.1
ENST00000310053.5
ENST00000494055.1
HLTF
helicase-like transcription factor
chr12_-_42983478 3.54 ENST00000345127.3
ENST00000547113.1
PRICKLE1
prickle homolog 1 (Drosophila)
chr9_+_40028620 3.40 ENST00000426179.1
AL353791.1
AL353791.1
chr14_-_91526922 3.34 ENST00000418736.2
ENST00000261991.3
RPS6KA5
ribosomal protein S6 kinase, 90kDa, polypeptide 5
chr9_+_75766763 3.15 ENST00000456643.1
ENST00000415424.1
ANXA1
annexin A1
chr4_+_6271558 3.14 ENST00000503569.1
ENST00000226760.1
WFS1
Wolfram syndrome 1 (wolframin)
chr19_+_19976683 2.97 ENST00000592725.1
ZNF253
zinc finger protein 253
chr17_+_61699766 2.86 ENST00000579585.1
ENST00000584573.1
ENST00000361733.3
ENST00000361357.3
MAP3K3
mitogen-activated protein kinase kinase kinase 3
chr21_+_46020497 2.75 ENST00000380102.2
KRTAP10-7
keratin associated protein 10-7
chrX_-_70474910 2.58 ENST00000373988.1
ENST00000373998.1
ZMYM3
zinc finger, MYM-type 3
chr2_+_66662510 2.47 ENST00000272369.9
ENST00000407092.2
MEIS1
Meis homeobox 1
chrX_-_70474499 2.46 ENST00000353904.2
ZMYM3
zinc finger, MYM-type 3
chr2_+_66662690 2.46 ENST00000488550.1
MEIS1
Meis homeobox 1
chr14_-_105635090 2.42 ENST00000331782.3
ENST00000347004.2
JAG2
jagged 2
chr2_-_86094764 2.38 ENST00000393808.3
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr21_+_17961006 2.38 ENST00000602323.1
LINC00478
long intergenic non-protein coding RNA 478
chr12_-_56615693 2.33 ENST00000394013.2
ENST00000345093.4
ENST00000551711.1
ENST00000552656.1
RNF41
ring finger protein 41
chr8_-_77912431 2.21 ENST00000357039.4
ENST00000522527.1
PEX2
peroxisomal biogenesis factor 2
chr2_-_89630186 2.05 ENST00000390264.2
IGKV2-40
immunoglobulin kappa variable 2-40
chr17_+_58755184 1.97 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
BCAS3
breast carcinoma amplified sequence 3
chr4_-_18023350 1.96 ENST00000539056.1
ENST00000382226.5
ENST00000326877.4
LCORL
ligand dependent nuclear receptor corepressor-like
chr9_-_124989804 1.95 ENST00000373755.2
ENST00000373754.2
LHX6
LIM homeobox 6
chr7_-_64023410 1.92 ENST00000447137.2
ZNF680
zinc finger protein 680
chr10_+_76586348 1.86 ENST00000372724.1
ENST00000287239.4
ENST00000372714.1
KAT6B
K(lysine) acetyltransferase 6B
chr15_+_41221536 1.82 ENST00000249749.5
DLL4
delta-like 4 (Drosophila)
chr17_-_8534031 1.80 ENST00000411957.1
ENST00000396239.1
ENST00000379980.4
MYH10
myosin, heavy chain 10, non-muscle
chr17_-_8534067 1.73 ENST00000360416.3
ENST00000269243.4
MYH10
myosin, heavy chain 10, non-muscle
chr12_+_51632666 1.71 ENST00000604900.1
DAZAP2
DAZ associated protein 2
chr2_-_220435963 1.70 ENST00000373876.1
ENST00000404537.1
ENST00000603926.1
ENST00000373873.4
ENST00000289656.3
OBSL1
obscurin-like 1
chr21_+_45993606 1.66 ENST00000400374.3
KRTAP10-4
keratin associated protein 10-4
chr3_+_197518100 1.62 ENST00000438796.2
ENST00000414675.2
ENST00000441090.2
ENST00000334859.4
ENST00000425562.2
LRCH3
leucine-rich repeats and calponin homology (CH) domain containing 3
chr19_-_14640005 1.58 ENST00000596853.1
ENST00000596075.1
ENST00000595992.1
ENST00000396969.4
ENST00000601533.1
ENST00000598692.1
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr12_+_12870055 1.56 ENST00000228872.4
CDKN1B
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
chr12_+_8662057 1.55 ENST00000382064.2
CLEC4D
C-type lectin domain family 4, member D
chr7_+_116502527 1.53 ENST00000361183.3
CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr11_-_2170786 1.51 ENST00000300632.5
IGF2
insulin-like growth factor 2 (somatomedin A)
chr6_+_18387570 1.47 ENST00000259939.3
RNF144B
ring finger protein 144B
chr19_+_19976714 1.47 ENST00000589717.1
ENST00000355650.4
ZNF253
zinc finger protein 253
chr8_-_57123815 1.45 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
PLAG1
pleiomorphic adenoma gene 1
chr19_-_22605136 1.42 ENST00000357774.5
ENST00000601553.1
ENST00000593657.1
ZNF98
zinc finger protein 98
chr13_+_20532848 1.40 ENST00000382874.2
ZMYM2
zinc finger, MYM-type 2
chr16_-_23521710 1.39 ENST00000562117.1
ENST00000567468.1
ENST00000562944.1
ENST00000309859.4
GGA2
golgi-associated, gamma adaptin ear containing, ARF binding protein 2
chr19_-_23869970 1.33 ENST00000601010.1
ZNF675
zinc finger protein 675
chr7_+_116502605 1.32 ENST00000458284.2
ENST00000490693.1
CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr11_-_47207390 1.30 ENST00000539589.1
ENST00000528462.1
PACSIN3
protein kinase C and casein kinase substrate in neurons 3
chr1_+_6845578 1.30 ENST00000467404.2
ENST00000439411.2
CAMTA1
calmodulin binding transcription activator 1
chr19_+_10736183 1.30 ENST00000590857.1
ENST00000588688.1
ENST00000586078.1
SLC44A2
solute carrier family 44 (choline transporter), member 2
chr3_+_107241882 1.28 ENST00000416476.2
BBX
bobby sox homolog (Drosophila)
chr11_-_124981475 1.27 ENST00000532156.1
ENST00000532407.1
ENST00000279968.4
ENST00000527766.1
ENST00000529583.1
ENST00000524373.1
ENST00000527271.1
ENST00000526175.1
ENST00000529609.1
ENST00000533273.1
ENST00000531909.1
ENST00000529530.1
TMEM218
transmembrane protein 218
chr16_-_53537105 1.27 ENST00000568596.1
ENST00000570004.1
ENST00000564497.1
ENST00000300245.4
ENST00000394657.7
AKTIP
AKT interacting protein
chr7_-_27702455 1.25 ENST00000265395.2
HIBADH
3-hydroxyisobutyrate dehydrogenase
chr6_-_119670919 1.24 ENST00000368468.3
MAN1A1
mannosidase, alpha, class 1A, member 1
chr14_-_76127519 1.21 ENST00000256319.6
C14orf1
chromosome 14 open reading frame 1
chr3_+_52489503 1.20 ENST00000345716.4
NISCH
nischarin
chr5_-_81046841 1.20 ENST00000509013.2
ENST00000505980.1
ENST00000509053.1
SSBP2
single-stranded DNA binding protein 2
chr3_-_141747950 1.19 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr3_+_52280220 1.17 ENST00000409502.3
ENST00000323588.4
PPM1M
protein phosphatase, Mg2+/Mn2+ dependent, 1M
chrX_-_117119243 1.17 ENST00000539496.1
ENST00000469946.1
KLHL13
kelch-like family member 13
chr8_-_93978346 1.16 ENST00000523580.1
TRIQK
triple QxxK/R motif containing
chr18_+_12991339 1.15 ENST00000589596.1
ENST00000506447.1
ENST00000325971.8
CEP192
centrosomal protein 192kDa
chr11_-_27494309 1.15 ENST00000389858.4
LGR4
leucine-rich repeat containing G protein-coupled receptor 4
chr8_-_93978333 1.14 ENST00000524037.1
ENST00000520430.1
ENST00000521617.1
TRIQK
triple QxxK/R motif containing
chr5_-_70320514 1.14 ENST00000517649.1
NAIP
NLR family, apoptosis inhibitory protein
chr13_+_20532900 1.14 ENST00000382871.2
ZMYM2
zinc finger, MYM-type 2
chr4_-_163085107 1.14 ENST00000379164.4
FSTL5
follistatin-like 5
chr1_-_22109484 1.14 ENST00000529637.1
USP48
ubiquitin specific peptidase 48
chr14_-_65769392 1.13 ENST00000555736.1
CTD-2509G16.5
CTD-2509G16.5
chr1_+_179051160 1.13 ENST00000367625.4
ENST00000352445.6
TOR3A
torsin family 3, member A
chr4_-_163085141 1.12 ENST00000427802.2
ENST00000306100.5
FSTL5
follistatin-like 5
chr18_+_3448455 1.11 ENST00000549780.1
TGIF1
TGFB-induced factor homeobox 1
chr8_-_93978309 1.10 ENST00000517858.1
ENST00000378861.5
TRIQK
triple QxxK/R motif containing
chr4_+_90800656 1.10 ENST00000394980.1
MMRN1
multimerin 1
chr3_+_52489606 1.10 ENST00000488380.1
ENST00000420808.2
NISCH
nischarin
chr4_-_110651143 1.09 ENST00000243501.5
PLA2G12A
phospholipase A2, group XIIA
chr3_+_52280173 1.08 ENST00000296487.4
PPM1M
protein phosphatase, Mg2+/Mn2+ dependent, 1M
chr7_+_106809406 1.08 ENST00000468410.1
ENST00000478930.1
ENST00000464009.1
ENST00000222574.4
HBP1
HMG-box transcription factor 1
chr4_-_110651111 1.07 ENST00000502283.1
PLA2G12A
phospholipase A2, group XIIA
chr11_-_27494279 1.07 ENST00000379214.4
LGR4
leucine-rich repeat containing G protein-coupled receptor 4
chr8_-_93978357 1.07 ENST00000522925.1
ENST00000522903.1
ENST00000537541.1
ENST00000518748.1
ENST00000519069.1
ENST00000521988.1
TRIQK
triple QxxK/R motif containing
chrX_+_102883887 1.06 ENST00000372625.3
ENST00000372624.3
TCEAL1
transcription elongation factor A (SII)-like 1
chr20_-_17539456 1.05 ENST00000544874.1
ENST00000377868.2
BFSP1
beaded filament structural protein 1, filensin
chr14_+_54976603 1.05 ENST00000557317.1
CGRRF1
cell growth regulator with ring finger domain 1
chr5_+_78532003 1.05 ENST00000396137.4
JMY
junction mediating and regulatory protein, p53 cofactor
chr7_-_149470297 1.04 ENST00000484747.1
ZNF467
zinc finger protein 467
chr2_+_3383439 1.03 ENST00000382110.2
ENST00000324266.5
TRAPPC12
trafficking protein particle complex 12
chr20_-_36156293 1.02 ENST00000373537.2
ENST00000414542.2
BLCAP
bladder cancer associated protein
chr4_-_175443788 1.01 ENST00000541923.1
HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr5_-_70320941 1.00 ENST00000523981.1
NAIP
NLR family, apoptosis inhibitory protein
chr10_+_99258625 1.00 ENST00000370664.3
UBTD1
ubiquitin domain containing 1
chr2_-_220436248 0.99 ENST00000265318.4
OBSL1
obscurin-like 1
chr9_+_140172200 0.99 ENST00000357503.2
TOR4A
torsin family 4, member A
chr20_-_36156125 0.99 ENST00000397135.1
ENST00000397137.1
BLCAP
bladder cancer associated protein
chr2_+_1507506 0.98 ENST00000425083.1
TPO
thyroid peroxidase
chr19_+_22235310 0.96 ENST00000600162.1
ZNF257
zinc finger protein 257
chr4_+_87515454 0.96 ENST00000427191.2
ENST00000436978.1
ENST00000502971.1
PTPN13
protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
chr11_-_69590101 0.96 ENST00000168712.1
FGF4
fibroblast growth factor 4
chr19_+_19639704 0.96 ENST00000514277.4
YJEFN3
YjeF N-terminal domain containing 3
chr18_-_19284724 0.95 ENST00000580981.1
ENST00000289119.2
ABHD3
abhydrolase domain containing 3
chr19_+_12035878 0.95 ENST00000254321.5
ENST00000538752.1
ENST00000590798.1
ZNF700
ZNF763
ZNF763
zinc finger protein 700
zinc finger protein 763
Uncharacterized protein; Zinc finger protein 763
chr19_+_16435625 0.95 ENST00000248071.5
ENST00000592003.1
KLF2
Kruppel-like factor 2
chr1_+_153700518 0.94 ENST00000318967.2
ENST00000456435.1
ENST00000435409.2
INTS3
integrator complex subunit 3
chr14_-_75530693 0.94 ENST00000555135.1
ENST00000357971.3
ENST00000553302.1
ENST00000555694.1
ENST00000238618.3
ACYP1
acylphosphatase 1, erythrocyte (common) type
chr6_-_85474219 0.93 ENST00000369663.5
TBX18
T-box 18
chr13_-_21348050 0.93 ENST00000382754.4
N6AMT2
N-6 adenine-specific DNA methyltransferase 2 (putative)
chr13_-_21348066 0.93 ENST00000382758.1
N6AMT2
N-6 adenine-specific DNA methyltransferase 2 (putative)
chr1_+_145477060 0.91 ENST00000369308.3
LIX1L
Lix1 homolog (mouse)-like
chr19_+_20959142 0.91 ENST00000344519.8
ZNF66
zinc finger protein 66
chr7_+_64254766 0.90 ENST00000307355.7
ENST00000359735.3
ZNF138
zinc finger protein 138
chr9_+_34652164 0.90 ENST00000441545.2
ENST00000553620.1
IL11RA
interleukin 11 receptor, alpha
chr2_+_113033164 0.90 ENST00000409871.1
ENST00000343936.4
ZC3H6
zinc finger CCCH-type containing 6
chr19_-_20844343 0.89 ENST00000595405.1
ZNF626
zinc finger protein 626
chr3_+_107241783 0.89 ENST00000415149.2
ENST00000402543.1
ENST00000325805.8
ENST00000427402.1
BBX
bobby sox homolog (Drosophila)
chr1_+_6845497 0.89 ENST00000473578.1
ENST00000557126.1
CAMTA1
calmodulin binding transcription activator 1
chr19_-_12551849 0.89 ENST00000595562.1
ENST00000301547.5
CTD-3105H18.16
ZNF443
Uncharacterized protein
zinc finger protein 443
chr7_-_64023441 0.89 ENST00000309683.6
ZNF680
zinc finger protein 680
chr9_-_99180597 0.89 ENST00000375256.4
ZNF367
zinc finger protein 367
chr1_-_22109682 0.88 ENST00000400301.1
ENST00000532737.1
USP48
ubiquitin specific peptidase 48
chr3_-_195163803 0.88 ENST00000326793.6
ACAP2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr2_+_220094479 0.87 ENST00000323348.5
ENST00000453432.1
ENST00000409849.1
ENST00000416565.1
ENST00000410034.3
ENST00000447157.1
ANKZF1
ankyrin repeat and zinc finger domain containing 1
chr16_-_28222797 0.86 ENST00000569951.1
ENST00000565698.1
XPO6
exportin 6
chr8_-_124408652 0.86 ENST00000287394.5
ATAD2
ATPase family, AAA domain containing 2
chr7_-_42276612 0.86 ENST00000395925.3
ENST00000437480.1
GLI3
GLI family zinc finger 3
chr9_-_111696224 0.85 ENST00000537196.1
IKBKAP
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
chr22_-_29137771 0.85 ENST00000439200.1
ENST00000405598.1
ENST00000398017.2
ENST00000425190.2
ENST00000348295.3
ENST00000382578.1
ENST00000382565.1
ENST00000382566.1
ENST00000382580.2
ENST00000328354.6
CHEK2
checkpoint kinase 2
chr19_+_21541777 0.84 ENST00000380870.4
ENST00000597810.1
ENST00000594245.1
ZNF738
zinc finger protein 738
chr6_+_32121218 0.84 ENST00000414204.1
ENST00000361568.2
ENST00000395523.1
PPT2
palmitoyl-protein thioesterase 2
chr22_-_29138386 0.83 ENST00000544772.1
CHEK2
checkpoint kinase 2
chr19_-_12595586 0.83 ENST00000397732.3
ZNF709
zinc finger protein 709
chr6_+_32121789 0.83 ENST00000437001.2
ENST00000375137.2
PPT2
palmitoyl-protein thioesterase 2
chr5_+_121647764 0.83 ENST00000261368.8
ENST00000379533.2
ENST00000379536.2
ENST00000379538.3
SNCAIP
synuclein, alpha interacting protein
chr5_+_121647877 0.82 ENST00000514497.2
ENST00000261367.7
SNCAIP
synuclein, alpha interacting protein
chrX_-_134049233 0.82 ENST00000370779.4
MOSPD1
motile sperm domain containing 1
chrX_-_70474377 0.82 ENST00000373978.1
ENST00000373981.1
ZMYM3
zinc finger, MYM-type 3
chr5_-_81046904 0.81 ENST00000515395.1
SSBP2
single-stranded DNA binding protein 2
chr5_+_43603229 0.81 ENST00000344920.4
ENST00000512996.2
NNT
nicotinamide nucleotide transhydrogenase
chr5_+_121647386 0.81 ENST00000542191.1
ENST00000506272.1
ENST00000508681.1
ENST00000509154.2
SNCAIP
synuclein, alpha interacting protein
chr4_+_175204818 0.80 ENST00000503780.1
CEP44
centrosomal protein 44kDa
chr19_+_21541732 0.80 ENST00000311015.3
ZNF738
zinc finger protein 738
chr16_-_30457048 0.80 ENST00000500504.2
ENST00000542752.1
SEPHS2
selenophosphate synthetase 2
chr3_+_15643476 0.80 ENST00000436193.1
ENST00000383778.4
BTD
biotinidase
chr6_+_32121908 0.80 ENST00000375143.2
ENST00000424499.1
PPT2
palmitoyl-protein thioesterase 2
chr19_+_41284121 0.80 ENST00000594800.1
ENST00000357052.2
ENST00000602173.1
RAB4B
RAB4B, member RAS oncogene family
chr19_-_11849697 0.79 ENST00000586121.1
ENST00000431998.1
ENST00000341191.6
ENST00000545749.1
ENST00000440527.1
ZNF823
zinc finger protein 823
chr19_-_23941639 0.79 ENST00000395385.3
ENST00000531570.1
ENST00000528059.1
ZNF681
zinc finger protein 681
chr1_+_179050512 0.79 ENST00000367627.3
TOR3A
torsin family 3, member A
chr19_-_39322497 0.77 ENST00000221418.4
ECH1
enoyl CoA hydratase 1, peroxisomal
chr3_+_15643140 0.77 ENST00000449107.1
BTD
biotinidase
chr1_+_65730385 0.76 ENST00000263441.7
ENST00000395325.3
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr3_+_15643245 0.76 ENST00000303498.5
ENST00000437172.1
BTD
biotinidase
chrX_-_153637612 0.76 ENST00000369807.1
ENST00000369808.3
DNASE1L1
deoxyribonuclease I-like 1
chrX_-_63425561 0.76 ENST00000374869.3
ENST00000330258.3
AMER1
APC membrane recruitment protein 1
chr10_-_44144292 0.76 ENST00000374433.2
ZNF32
zinc finger protein 32
chr16_-_15463926 0.76 ENST00000432570.2
NPIPA5
nuclear pore complex interacting protein family, member A5
chr6_+_32146131 0.75 ENST00000375094.3
RNF5
ring finger protein 5, E3 ubiquitin protein ligase
chr6_+_43028182 0.75 ENST00000394058.1
KLC4
kinesin light chain 4
chr5_+_121647924 0.75 ENST00000414317.2
SNCAIP
synuclein, alpha interacting protein
chr3_+_48481658 0.75 ENST00000438607.2
TMA7
translation machinery associated 7 homolog (S. cerevisiae)
chr3_-_3221358 0.75 ENST00000424814.1
ENST00000450014.1
ENST00000231948.4
ENST00000432408.2
CRBN
cereblon
chr19_+_22469210 0.75 ENST00000601693.1
ZNF729
zinc finger protein 729
chr10_-_101945771 0.73 ENST00000370408.2
ENST00000407654.3
ERLIN1
ER lipid raft associated 1
chr13_-_41240717 0.72 ENST00000379561.5
FOXO1
forkhead box O1
chr15_+_25068773 0.71 ENST00000400100.1
ENST00000400098.1
SNRPN
small nuclear ribonucleoprotein polypeptide N
chr5_-_137514333 0.71 ENST00000411594.2
ENST00000430331.1
BRD8
bromodomain containing 8
chr3_+_111718173 0.71 ENST00000494932.1
TAGLN3
transgelin 3
chr1_-_28969517 0.71 ENST00000263974.4
ENST00000373824.4
TAF12
TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
chr7_-_38403077 0.70 ENST00000426402.2
TRGV2
T cell receptor gamma variable 2
chr1_+_20208870 0.70 ENST00000375120.3
OTUD3
OTU domain containing 3
chr7_-_150652924 0.70 ENST00000330883.4
KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr4_-_175443484 0.70 ENST00000514584.1
ENST00000542498.1
ENST00000296521.7
ENST00000422112.2
ENST00000504433.1
HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr19_+_19639670 0.70 ENST00000436027.5
YJEFN3
YjeF N-terminal domain containing 3
chr13_+_20207782 0.69 ENST00000414242.2
ENST00000361479.5
MPHOSPH8
M-phase phosphoprotein 8
chr10_-_44144152 0.69 ENST00000395797.1
ZNF32
zinc finger protein 32
chr3_-_28390415 0.68 ENST00000414162.1
ENST00000420543.2
AZI2
5-azacytidine induced 2
chr5_-_137514288 0.68 ENST00000454473.1
ENST00000418329.1
ENST00000455658.2
ENST00000230901.5
ENST00000402931.1
BRD8
bromodomain containing 8
chr19_-_21950362 0.68 ENST00000358296.6
ZNF100
zinc finger protein 100
chr5_+_43602750 0.68 ENST00000505678.2
ENST00000512422.1
ENST00000264663.5
NNT
nicotinamide nucleotide transhydrogenase
chr17_+_18086392 0.66 ENST00000541285.1
ALKBH5
alkB, alkylation repair homolog 5 (E. coli)
chr19_-_19843900 0.66 ENST00000344099.3
ZNF14
zinc finger protein 14
chrX_+_102631248 0.66 ENST00000361298.4
ENST00000372645.3
ENST00000372635.1
NGFRAP1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr13_-_20437772 0.66 ENST00000337963.4
ZMYM5
zinc finger, MYM-type 5
chr12_+_7055631 0.66 ENST00000543115.1
ENST00000399448.1
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr2_+_62933001 0.65 ENST00000263991.5
ENST00000354487.3
EHBP1
EH domain binding protein 1
chr7_-_14029283 0.65 ENST00000433547.1
ENST00000405192.2
ETV1
ets variant 1
chr2_+_1488435 0.64 ENST00000446278.1
ENST00000469607.1
TPO
thyroid peroxidase
chr7_+_64254793 0.64 ENST00000494380.1
ENST00000440155.2
ENST00000440598.1
ENST00000437743.1
ZNF138
zinc finger protein 138
chr10_+_89264625 0.63 ENST00000371996.4
ENST00000371994.4
MINPP1
multiple inositol-polyphosphate phosphatase 1
chr19_-_59084647 0.63 ENST00000594234.1
ENST00000596039.1
MZF1
myeloid zinc finger 1
chr8_-_41522719 0.63 ENST00000335651.6
ANK1
ankyrin 1, erythrocytic
chr10_+_89622870 0.63 ENST00000371953.3
PTEN
phosphatase and tensin homolog
chr5_-_89705537 0.63 ENST00000522864.1
ENST00000522083.1
ENST00000522565.1
ENST00000522842.1
ENST00000283122.3
CETN3
centrin, EF-hand protein, 3
chr2_+_44396000 0.63 ENST00000409895.4
ENST00000409432.3
ENST00000282412.4
ENST00000378551.2
ENST00000345249.4
PPM1B
protein phosphatase, Mg2+/Mn2+ dependent, 1B
chr6_-_132834184 0.63 ENST00000367941.2
ENST00000367937.4
STX7
syntaxin 7
chr19_+_41869894 0.62 ENST00000413014.2
TMEM91
transmembrane protein 91
chr19_+_21579908 0.62 ENST00000596302.1
ENST00000392288.2
ENST00000594390.1
ENST00000355504.4
ZNF493
zinc finger protein 493
chr9_-_33264676 0.62 ENST00000472232.3
ENST00000379704.2
BAG1
BCL2-associated athanogene

Network of associatons between targets according to the STRING database.

First level regulatory network of PBX3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 1.8 GO:0072554 blood vessel lumenization(GO:0072554)
1.4 4.1 GO:0021558 trochlear nerve development(GO:0021558) auditory receptor cell fate determination(GO:0042668) negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of pro-B cell differentiation(GO:2000974)
1.2 3.7 GO:0014839 myoblast migration involved in skeletal muscle regeneration(GO:0014839)
0.9 3.5 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.9 3.5 GO:0021592 fourth ventricle development(GO:0021592)
0.7 3.3 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.6 2.4 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.6 1.7 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.6 2.2 GO:0061289 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.3 0.9 GO:0060823 canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060823)
0.3 0.9 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.3 1.5 GO:0006740 NADPH regeneration(GO:0006740)
0.3 3.0 GO:0006983 ER overload response(GO:0006983)
0.3 0.8 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.3 2.3 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.3 1.8 GO:0016128 phytosteroid metabolic process(GO:0016128) phytosteroid biosynthetic process(GO:0016129)
0.3 1.0 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.2 2.5 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.2 0.7 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.2 0.7 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.2 1.0 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.2 0.6 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.2 1.3 GO:0006574 valine catabolic process(GO:0006574)
0.2 1.2 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.2 0.6 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.2 0.6 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.2 1.6 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.2 5.6 GO:0035855 megakaryocyte development(GO:0035855)
0.2 0.9 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.2 2.6 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.2 0.5 GO:0044805 late nucleophagy(GO:0044805)
0.2 0.9 GO:0060594 frontal suture morphogenesis(GO:0060364) mammary gland specification(GO:0060594)
0.2 2.4 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.2 1.5 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.2 0.7 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.2 1.5 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.2 0.5 GO:1904719 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.2 0.6 GO:1903984 negative regulation of ribosome biogenesis(GO:0090071) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.2 2.0 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 0.4 GO:0043060 meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.1 0.9 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.1 0.6 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
0.1 0.7 GO:1902617 response to fluoride(GO:1902617)
0.1 1.3 GO:2001300 lipoxin metabolic process(GO:2001300)
0.1 0.5 GO:0050976 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976)
0.1 0.7 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 0.4 GO:0002071 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.1 0.8 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.1 2.4 GO:0006768 biotin metabolic process(GO:0006768)
0.1 0.6 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.1 1.0 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.1 2.3 GO:0048243 norepinephrine secretion(GO:0048243)
0.1 0.3 GO:0032792 regulation of tolerance induction dependent upon immune response(GO:0002652) negative regulation of CREB transcription factor activity(GO:0032792) regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831) positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.1 1.3 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 2.2 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.1 0.6 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.1 0.7 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 0.5 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.1 0.6 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.1 2.1 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.1 0.1 GO:1900214 pronephric field specification(GO:0039003) pattern specification involved in pronephros development(GO:0039017) kidney field specification(GO:0072004) regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072304) negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072305) mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis(GO:0072309) mesenchymal cell apoptotic process involved in metanephros development(GO:1900200) apoptotic process involved in metanephric collecting duct development(GO:1900204) apoptotic process involved in metanephric nephron tubule development(GO:1900205) regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900211) negative regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900212) regulation of apoptotic process involved in metanephric collecting duct development(GO:1900214) negative regulation of apoptotic process involved in metanephric collecting duct development(GO:1900215) regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900217) negative regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900218) mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:1901147) regulation of metanephric DCT cell differentiation(GO:2000592) positive regulation of metanephric DCT cell differentiation(GO:2000594)
0.1 1.7 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 3.2 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.1 2.0 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 6.1 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 1.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.3 GO:0002424 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072)
0.1 0.8 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 0.3 GO:0044108 cellular alcohol metabolic process(GO:0044107) cellular alcohol biosynthetic process(GO:0044108)
0.1 0.4 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1 1.5 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.1 0.9 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 0.4 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1 1.3 GO:0015871 choline transport(GO:0015871)
0.1 2.7 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.1 1.5 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.1 0.5 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 0.6 GO:1903750 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.1 0.5 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 0.4 GO:0002760 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.1 1.6 GO:0006590 thyroid hormone generation(GO:0006590)
0.1 0.3 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.1 0.4 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.1 0.4 GO:0051344 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.1 0.2 GO:0060061 Spemann organizer formation(GO:0060061)
0.1 1.0 GO:0000338 protein deneddylation(GO:0000338)
0.1 1.1 GO:0070307 lens fiber cell development(GO:0070307)
0.1 0.7 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 0.6 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.1 0.4 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.1 0.1 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.1 0.8 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.1 0.2 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.1 0.6 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.1 0.5 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.2 GO:0032079 positive regulation of endodeoxyribonuclease activity(GO:0032079)
0.0 1.2 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.1 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.0 1.2 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.2 GO:0042361 menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)
0.0 3.7 GO:0006301 postreplication repair(GO:0006301)
0.0 2.0 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.0 0.2 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.3 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.5 GO:0015074 DNA integration(GO:0015074)
0.0 0.8 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.1 GO:1903464 negative regulation of mitotic cell cycle DNA replication(GO:1903464)
0.0 0.8 GO:0006308 DNA catabolic process(GO:0006308)
0.0 0.9 GO:0016180 snRNA processing(GO:0016180)
0.0 0.4 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.5 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.2 GO:2000035 regulation of stem cell division(GO:2000035) positive regulation of histone H3-K9 acetylation(GO:2000617)
0.0 0.5 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.6 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0 8.4 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.2 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.3 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 1.2 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.1 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.3 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.1 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.1 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.0 0.7 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.3 GO:0030497 fatty acid elongation(GO:0030497)
0.0 0.3 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 0.2 GO:0030091 protein repair(GO:0030091)
0.0 1.3 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 1.8 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.4 GO:0044030 regulation of DNA methylation(GO:0044030)
0.0 0.5 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.2 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.5 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 1.0 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.2 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.3 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.7 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.1 GO:1901911 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.5 GO:0032098 regulation of appetite(GO:0032098)
0.0 0.1 GO:0039536 negative regulation of MDA-5 signaling pathway(GO:0039534) negative regulation of RIG-I signaling pathway(GO:0039536) positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.2 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.2 GO:0007512 adult heart development(GO:0007512)
0.0 0.5 GO:0043536 positive regulation of blood vessel endothelial cell migration(GO:0043536)
0.0 0.3 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.3 GO:0045116 protein neddylation(GO:0045116)
0.0 0.4 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0 0.1 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 0.2 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.1 GO:1902572 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 0.4 GO:0030488 tRNA methylation(GO:0030488)
0.0 2.7 GO:0031424 keratinization(GO:0031424)
0.0 0.1 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.0 2.2 GO:0002576 platelet degranulation(GO:0002576)
0.0 0.2 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.6 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.4 GO:0007140 male meiosis(GO:0007140)
0.0 0.3 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.0 0.3 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0 0.9 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.1 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.0 0.2 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.3 GO:0097513 myosin II filament(GO:0097513)
0.5 3.7 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232) extrinsic component of endosome membrane(GO:0031313)
0.3 2.3 GO:1990393 3M complex(GO:1990393)
0.2 2.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.2 0.6 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.2 0.9 GO:0070876 SOSS complex(GO:0070876)
0.2 1.2 GO:0070695 FHF complex(GO:0070695)
0.2 2.9 GO:0008290 F-actin capping protein complex(GO:0008290)
0.2 2.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.2 1.9 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 0.4 GO:0005715 late recombination nodule(GO:0005715)
0.1 0.7 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 1.8 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.1 1.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.4 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.8 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.7 GO:0005610 laminin-5 complex(GO:0005610)
0.1 2.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 2.0 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 1.0 GO:0030008 TRAPP complex(GO:0030008)
0.1 0.7 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.2 GO:0097196 Shu complex(GO:0097196)
0.1 0.7 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.8 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.1 0.5 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.8 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.7 GO:0000124 SAGA complex(GO:0000124)
0.0 3.7 GO:0045095 keratin filament(GO:0045095)
0.0 1.2 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.7 GO:0005687 U4 snRNP(GO:0005687)
0.0 5.1 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 8.1 GO:0043197 dendritic spine(GO:0043197)
0.0 0.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.7 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 3.2 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.2 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.8 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 1.5 GO:0008180 COP9 signalosome(GO:0008180)
0.0 2.7 GO:0000502 proteasome complex(GO:0000502)
0.0 0.3 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 2.6 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 1.2 GO:0097542 ciliary tip(GO:0097542)
0.0 0.6 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 2.7 GO:0035579 specific granule membrane(GO:0035579)
0.0 0.3 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.8 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.2 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.6 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.6 GO:0001772 immunological synapse(GO:0001772)
0.0 2.0 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 1.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.6 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.1 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.3 GO:0031092 platelet alpha granule membrane(GO:0031092)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.6 2.3 GO:0047708 biotinidase activity(GO:0047708)
0.6 1.7 GO:0052857 NADHX epimerase activity(GO:0052856) NADPHX epimerase activity(GO:0052857)
0.5 3.7 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.5 1.5 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.3 1.3 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.3 1.3 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.3 1.6 GO:0004447 iodide peroxidase activity(GO:0004447)
0.3 0.8 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.2 2.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.2 2.5 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.2 0.6 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.2 2.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.2 1.0 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.2 0.6 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.2 0.9 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.2 2.2 GO:0031386 protein tag(GO:0031386)
0.2 2.4 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.2 0.7 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.2 0.6 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.2 4.2 GO:0005112 Notch binding(GO:0005112)
0.2 0.9 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 1.3 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 3.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 3.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.4 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.1 1.8 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.1 1.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 1.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 1.5 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 5.6 GO:0044390 ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.1 0.6 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.1 1.0 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 1.0 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 1.3 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 0.3 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.1 0.4 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 2.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 6.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 0.7 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 1.4 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 0.2 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.1 1.6 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.1 0.3 GO:0052812 phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.1 0.2 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 0.5 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.1 0.3 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.1 1.1 GO:0070410 co-SMAD binding(GO:0070410)
0.1 0.6 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 0.4 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.1 0.2 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.1 0.5 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.3 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.4 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.1 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.2 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 2.1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 4.3 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 3.1 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.3 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.3 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 2.2 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 1.5 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.2 GO:1903136 cuprous ion binding(GO:1903136)
0.0 1.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 2.4 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.3 GO:0015288 porin activity(GO:0015288)
0.0 0.4 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 1.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.4 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.3 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.7 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 7.0 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.7 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 3.4 GO:0005496 steroid binding(GO:0005496)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0030984 kininogen binding(GO:0030984)
0.0 2.7 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.4 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.6 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.0 1.0 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.1 GO:0034432 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 1.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
0.0 0.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.4 GO:0022840 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0016594 glycine binding(GO:0016594)
0.0 0.3 GO:0005521 lamin binding(GO:0005521)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 0.8 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.3 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.3 GO:0005523 tropomyosin binding(GO:0005523)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.3 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 2.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 2.9 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 1.6 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 3.2 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 2.6 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.7 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 1.4 PID ATM PATHWAY ATM pathway
0.0 3.3 PID NOTCH PATHWAY Notch signaling pathway
0.0 2.1 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.7 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.8 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.6 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 2.3 PID E2F PATHWAY E2F transcription factor network
0.0 5.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.9 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.3 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.7 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.0 PID AURORA B PATHWAY Aurora B signaling
0.0 2.7 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 0.6 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 1.6 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 4.8 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 3.2 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 3.3 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 3.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 1.5 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 1.7 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 3.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 1.0 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 1.6 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 1.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.3 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.7 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.9 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.2 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 1.3 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.5 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.6 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.8 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.6 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.4 REACTOME MEIOSIS Genes involved in Meiosis
0.0 0.8 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.6 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 2.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.2 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 1.8 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 8.0 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 4.2 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.6 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.4 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.0 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.9 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.6 REACTOME KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha