Project

Inflammatory response time course, HUVEC (Wada et al., 2009)

Navigation
Downloads

Results for PGR

Z-value: 0.75

Motif logo

Transcription factors associated with PGR

Gene Symbol Gene ID Gene Info
ENSG00000082175.10 progesterone receptor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PGRhg19_v2_chr11_-_100999775_100999801,
hg19_v2_chr11_-_101000445_101000465
0.376.5e-02Click!

Activity profile of PGR motif

Sorted Z-values of PGR motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_+_32838801 2.33 ENST00000542859.1
furry homolog (Drosophila)
chr3_-_149051194 1.80 ENST00000470080.1
transmembrane 4 L six family member 18
chr7_+_30960915 1.75 ENST00000441328.2
ENST00000409899.1
ENST00000409611.1
aquaporin 1 (Colton blood group)
chr2_+_173686303 1.52 ENST00000397087.3
Rap guanine nucleotide exchange factor (GEF) 4
chr5_-_94417314 1.39 ENST00000505208.1
multiple C2 domains, transmembrane 1
chr9_-_107690420 1.37 ENST00000423487.2
ENST00000374733.1
ENST00000374736.3
ATP-binding cassette, sub-family A (ABC1), member 1
chr9_+_82188077 1.32 ENST00000425506.1
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr6_-_76203345 1.25 ENST00000393004.2
filamin A interacting protein 1
chr2_-_188312971 1.19 ENST00000410068.1
ENST00000447403.1
ENST00000410102.1
calcitonin receptor-like
chr12_+_79258547 1.19 ENST00000457153.2
synaptotagmin I
chr5_-_94417339 1.17 ENST00000429576.2
ENST00000508509.1
ENST00000510732.1
multiple C2 domains, transmembrane 1
chr3_-_149051444 1.15 ENST00000296059.2
transmembrane 4 L six family member 18
chr11_+_6897856 0.98 ENST00000379829.2
olfactory receptor, family 10, subfamily A, member 4
chr7_+_130126012 0.95 ENST00000341441.5
mesoderm specific transcript
chr6_-_76203454 0.93 ENST00000237172.7
filamin A interacting protein 1
chr17_+_61086917 0.91 ENST00000424789.2
ENST00000389520.4
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr14_+_63671577 0.90 ENST00000555125.1
ras homolog family member J
chr4_-_90759440 0.89 ENST00000336904.3
synuclein, alpha (non A4 component of amyloid precursor)
chr16_-_28506840 0.88 ENST00000569430.1
ceroid-lipofuscinosis, neuronal 3
chr8_+_82644669 0.83 ENST00000297265.4
charged multivesicular body protein 4C
chr15_+_31658349 0.83 ENST00000558844.1
Kruppel-like factor 13
chr19_+_30863271 0.82 ENST00000355537.3
zinc finger protein 536
chr6_-_75915757 0.78 ENST00000322507.8
collagen, type XII, alpha 1
chrX_-_100641155 0.71 ENST00000372880.1
ENST00000308731.7
Bruton agammaglobulinemia tyrosine kinase
chr1_-_248903150 0.68 ENST00000590317.1
LY6/PLAUR domain containing 8
chr1_-_85870177 0.67 ENST00000542148.1
dimethylarginine dimethylaminohydrolase 1
chr2_-_216300784 0.64 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
fibronectin 1
chr2_-_183387430 0.60 ENST00000410103.1
phosphodiesterase 1A, calmodulin-dependent
chr7_+_130126165 0.60 ENST00000427521.1
ENST00000416162.2
ENST00000378576.4
mesoderm specific transcript
chrX_+_54834004 0.58 ENST00000375068.1
melanoma antigen family D, 2
chr1_+_154474689 0.57 ENST00000368482.4
tudor domain containing 10
chr21_+_17566643 0.57 ENST00000419952.1
ENST00000445461.2
long intergenic non-protein coding RNA 478
chr21_+_17791648 0.56 ENST00000602892.1
ENST00000418813.2
ENST00000435697.1
long intergenic non-protein coding RNA 478
chr9_+_116225999 0.56 ENST00000317613.6
regulator of G-protein signaling 3
chr9_+_2159850 0.54 ENST00000416751.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr3_-_151102529 0.54 ENST00000302632.3
purinergic receptor P2Y, G-protein coupled, 12
chr3_+_52454971 0.54 ENST00000465863.1
PHD finger protein 7
chrX_+_54834159 0.51 ENST00000375053.2
ENST00000347546.4
ENST00000375062.4
melanoma antigen family D, 2
chr2_+_96991935 0.51 ENST00000361124.4
ENST00000420728.1
ENST00000542887.1
inositol 1,4,5-trisphosphate receptor interacting protein-like 1
chr14_-_35182994 0.50 ENST00000341223.3
cofilin 2 (muscle)
chr12_-_71551652 0.50 ENST00000546561.1
tetraspanin 8
chr5_+_140797296 0.49 ENST00000398594.2
protocadherin gamma subfamily B, 7
chr1_-_110933663 0.48 ENST00000369781.4
ENST00000541986.1
ENST00000369779.4
solute carrier family 16, member 4
chr3_+_25469802 0.48 ENST00000330688.4
retinoic acid receptor, beta
chrX_-_112084043 0.47 ENST00000304758.1
angiomotin
chr13_-_99667960 0.46 ENST00000448493.2
dedicator of cytokinesis 9
chr9_+_115513003 0.43 ENST00000374232.3
sorting nexin family member 30
chr11_-_17229480 0.43 ENST00000532035.1
ENST00000540361.1
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
chr7_-_5821225 0.43 ENST00000416985.1
ring finger protein 216
chrX_-_45060135 0.43 ENST00000398000.2
ENST00000377934.4
chromosome X open reading frame 36
chr2_-_74667612 0.42 ENST00000305557.5
ENST00000233330.6
rhotekin
chr1_+_154975258 0.41 ENST00000417934.2
zinc finger and BTB domain containing 7B
chr20_-_25320367 0.40 ENST00000450393.1
ENST00000491682.1
abhydrolase domain containing 12
chr16_-_50913188 0.40 ENST00000569986.1
CTD-2034I21.1
chrX_+_15525426 0.40 ENST00000342014.6
BMX non-receptor tyrosine kinase
chr1_-_145039771 0.39 ENST00000493130.2
ENST00000532801.1
ENST00000478649.2
phosphodiesterase 4D interacting protein
chr1_-_179834311 0.39 ENST00000553856.1
Homo sapiens torsin A interacting protein 2 (TOR1AIP2), transcript variant 1, mRNA.
chr2_+_191334212 0.39 ENST00000444317.1
ENST00000535751.1
major facilitator superfamily domain containing 6
chr13_+_102104980 0.38 ENST00000545560.2
integrin, beta-like 1 (with EGF-like repeat domains)
chr3_+_25469724 0.38 ENST00000437042.2
retinoic acid receptor, beta
chr10_+_124030819 0.38 ENST00000260723.4
ENST00000368994.2
BTB (POZ) domain containing 16
chr3_-_128294929 0.37 ENST00000356020.2
chromosome 3 open reading frame 27
chr7_+_73442487 0.36 ENST00000380575.4
ENST00000380584.4
ENST00000458204.1
ENST00000357036.5
ENST00000417091.1
ENST00000429192.1
ENST00000442310.1
ENST00000380553.4
ENST00000380576.5
ENST00000428787.1
ENST00000320399.6
elastin
chr9_-_15510989 0.36 ENST00000380715.1
ENST00000380716.4
ENST00000380738.4
ENST00000380733.4
PC4 and SFRS1 interacting protein 1
chr19_-_41903161 0.36 ENST00000602129.1
ENST00000593771.1
ENST00000596905.1
ENST00000221233.4
exosome component 5
chr6_+_74405501 0.35 ENST00000437994.2
ENST00000422508.2
CD109 molecule
chr6_+_74405804 0.35 ENST00000287097.5
CD109 molecule
chr16_-_66952779 0.35 ENST00000570262.1
ENST00000394055.3
ENST00000299752.4
cadherin 16, KSP-cadherin
chr6_-_32157947 0.35 ENST00000375050.4
pre-B-cell leukemia homeobox 2
chr7_+_73442422 0.35 ENST00000358929.4
ENST00000431562.1
ENST00000320492.7
ENST00000438906.1
elastin
chr16_-_66952742 0.34 ENST00000565235.2
ENST00000568632.1
ENST00000565796.1
cadherin 16, KSP-cadherin
chr6_-_46922659 0.34 ENST00000265417.7
G protein-coupled receptor 116
chr2_+_163175394 0.33 ENST00000446271.1
ENST00000429691.2
grancalcin, EF-hand calcium binding protein
chrX_+_100743031 0.32 ENST00000423738.3
armadillo repeat containing, X-linked 4
chr11_-_73693875 0.32 ENST00000536983.1
uncoupling protein 2 (mitochondrial, proton carrier)
chr22_+_30279144 0.31 ENST00000401950.2
ENST00000333027.3
ENST00000445401.1
ENST00000323630.5
ENST00000351488.3
myotubularin related protein 3
chr5_+_102201430 0.31 ENST00000438793.3
ENST00000346918.2
peptidylglycine alpha-amidating monooxygenase
chr17_-_3337135 0.30 ENST00000248384.1
olfactory receptor, family 1, subfamily E, member 2
chr2_+_64681219 0.30 ENST00000238875.5
lectin, galactoside-binding-like
chr2_-_183387064 0.30 ENST00000536095.1
ENST00000331935.6
ENST00000358139.2
ENST00000456212.1
phosphodiesterase 1A, calmodulin-dependent
chr12_+_57849048 0.29 ENST00000266646.2
inhibin, beta E
chr2_+_10560147 0.29 ENST00000422133.1
hippocalcin-like 1
chr22_-_31688381 0.29 ENST00000487265.2
phosphoinositide-3-kinase interacting protein 1
chr17_-_7760457 0.28 ENST00000576384.1
LSM domain containing 1
chr7_-_37026108 0.28 ENST00000396045.3
engulfment and cell motility 1
chr14_+_22985251 0.28 ENST00000390510.1
T cell receptor alpha joining 27
chr6_+_72926145 0.28 ENST00000425662.2
ENST00000453976.2
regulating synaptic membrane exocytosis 1
chr5_+_138629628 0.27 ENST00000508689.1
ENST00000514528.1
matrin 3
chr4_-_88450612 0.27 ENST00000418378.1
ENST00000282470.6
SPARC-like 1 (hevin)
chr12_+_56661461 0.27 ENST00000546544.1
ENST00000553234.1
coenzyme Q10 homolog A (S. cerevisiae)
chr12_-_70093190 0.26 ENST00000330891.5
bestrophin 3
chr2_-_27531313 0.26 ENST00000296099.2
urocortin
chr3_-_114343039 0.26 ENST00000481632.1
zinc finger and BTB domain containing 20
chr17_+_73997796 0.26 ENST00000586261.1
cyclin-dependent kinase 3
chr7_+_23637763 0.26 ENST00000410069.1
coiled-coil domain containing 126
chr19_+_41119323 0.26 ENST00000599724.1
ENST00000597071.1
ENST00000243562.9
latent transforming growth factor beta binding protein 4
chr15_+_65843130 0.26 ENST00000569894.1
protein tyrosine phosphatase-like A domain containing 1
chr17_-_7760779 0.25 ENST00000335155.5
ENST00000575071.1
LSM domain containing 1
chr18_+_6729698 0.25 ENST00000383472.4
Rho GTPase activating protein 28
chr9_+_116298778 0.25 ENST00000462143.1
regulator of G-protein signaling 3
chr20_+_11008408 0.25 ENST00000378252.1
chromosome 20 open reading frame 187
chr1_-_26394114 0.24 ENST00000374272.3
tripartite motif containing 63, E3 ubiquitin protein ligase
chr17_-_15522826 0.24 ENST00000395906.3
CMT1A duplicated region transcript 1
chr17_+_19186292 0.24 ENST00000395626.1
ENST00000571254.1
epsin 2
chr6_-_159466042 0.24 ENST00000338313.5
T-cell activation RhoGTPase activating protein
chr17_-_43487780 0.24 ENST00000532038.1
ENST00000528677.1
Rho GTPase activating protein 27
chr7_+_128312346 0.24 ENST00000480462.1
ENST00000378704.3
ENST00000477515.1
family with sequence similarity 71, member F2
chr17_-_42466864 0.24 ENST00000353281.4
ENST00000262407.5
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
chr17_-_71088797 0.24 ENST00000580557.1
ENST00000579732.1
ENST00000578620.1
ENST00000542342.2
ENST00000255559.3
ENST00000579018.1
solute carrier family 39, member 11
chr19_+_39214797 0.23 ENST00000440400.1
actinin, alpha 4
chr6_+_30131318 0.23 ENST00000376688.1
tripartite motif containing 15
chr7_+_73442457 0.23 ENST00000438880.1
ENST00000414324.1
ENST00000380562.4
elastin
chr5_+_102201509 0.22 ENST00000348126.2
ENST00000379787.4
peptidylglycine alpha-amidating monooxygenase
chr8_+_133931648 0.21 ENST00000519178.1
ENST00000542445.1
thyroglobulin
chr2_+_191208196 0.21 ENST00000392329.2
ENST00000322522.4
ENST00000430311.1
ENST00000541441.1
inositol polyphosphate-1-phosphatase
chr15_-_43877062 0.21 ENST00000381885.1
ENST00000396923.3
diphosphoinositol pentakisphosphate kinase 1
chr22_-_41252962 0.21 ENST00000216218.3
suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
chr1_-_35658736 0.21 ENST00000357214.5
splicing factor proline/glutamine-rich
chr2_+_74361599 0.20 ENST00000401851.1
MGC10955
chr16_+_56970567 0.20 ENST00000563911.1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr20_+_34129770 0.20 ENST00000348547.2
ENST00000357394.4
ENST00000447986.1
ENST00000279052.6
ENST00000416206.1
ENST00000411577.1
ENST00000413587.1
ERGIC and golgi 3
chr7_+_143657027 0.20 ENST00000392899.1
olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
chr6_-_43276535 0.20 ENST00000372569.3
ENST00000274990.4
cysteine-rich protein 3
chr7_+_31003621 0.20 ENST00000326139.2
growth hormone releasing hormone receptor
chr9_-_140196703 0.20 ENST00000356628.2
NOTCH-regulated ankyrin repeat protein
chr5_+_102201722 0.19 ENST00000274392.9
ENST00000455264.2
peptidylglycine alpha-amidating monooxygenase
chr3_+_148583043 0.19 ENST00000296046.3
carboxypeptidase A3 (mast cell)
chr10_-_48416849 0.19 ENST00000249598.1
growth differentiation factor 2
chr7_-_229557 0.19 ENST00000514988.1
Uncharacterized protein
chr17_+_45286706 0.19 ENST00000393450.1
ENST00000572303.1
myosin, light chain 4, alkali; atrial, embryonic
chr2_-_183106641 0.19 ENST00000346717.4
phosphodiesterase 1A, calmodulin-dependent
chr8_+_11534462 0.19 ENST00000528712.1
ENST00000532977.1
GATA binding protein 4
chr11_+_57105991 0.19 ENST00000263314.2
purinergic receptor P2X, ligand-gated ion channel, 3
chrX_-_78622805 0.19 ENST00000373298.2
integral membrane protein 2A
chr3_+_158991025 0.19 ENST00000337808.6
IQCJ-SCHIP1 readthrough
chr6_-_154831779 0.19 ENST00000607772.1
CNKSR family member 3
chr3_-_149510553 0.19 ENST00000462519.2
ENST00000446160.1
ENST00000383050.3
ankyrin repeat and ubiquitin domain containing 1
chr8_+_9953214 0.19 ENST00000382490.5
methionine sulfoxide reductase A
chr2_-_179315786 0.18 ENST00000457633.1
ENST00000438687.3
ENST00000325748.4
protein kinase, interferon-inducible double stranded RNA dependent activator
chr19_+_13135731 0.18 ENST00000587260.1
nuclear factor I/X (CCAAT-binding transcription factor)
chr13_+_73632897 0.18 ENST00000377687.4
Kruppel-like factor 5 (intestinal)
chr17_+_46970134 0.18 ENST00000503641.1
ENST00000514808.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr3_+_149530836 0.18 ENST00000466478.1
ENST00000491086.1
ENST00000467977.1
ring finger protein 13
chr11_-_65625014 0.18 ENST00000534784.1
cofilin 1 (non-muscle)
chr16_+_86600857 0.18 ENST00000320354.4
forkhead box C2 (MFH-1, mesenchyme forkhead 1)
chr14_+_65878565 0.18 ENST00000556518.1
ENST00000557164.1
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr19_-_42947121 0.18 ENST00000601181.1
chemokine (C-X-C motif) ligand 17
chr1_-_156828810 0.17 ENST00000368195.3
insulin receptor-related receptor
chr5_-_131347501 0.17 ENST00000543479.1
acyl-CoA synthetase long-chain family member 6
chr14_-_75330537 0.17 ENST00000556084.2
ENST00000556489.2
ENST00000445876.1
prospero homeobox 2
chr17_+_45286387 0.17 ENST00000572316.1
ENST00000354968.1
ENST00000576874.1
ENST00000536623.2
myosin, light chain 4, alkali; atrial, embryonic
chr2_+_48796120 0.17 ENST00000394754.1
STON1-GTF2A1L readthrough
chr7_-_92855762 0.17 ENST00000453812.2
ENST00000394468.2
HEPACAM family member 2
chr10_-_72142345 0.17 ENST00000373224.1
ENST00000446961.1
ENST00000358141.2
ENST00000357631.2
leucine rich repeat containing 20
chr11_-_66725837 0.17 ENST00000393958.2
ENST00000393960.1
ENST00000524491.1
ENST00000355677.3
pyruvate carboxylase
chr7_+_73507409 0.17 ENST00000538333.3
LIM domain kinase 1
chr2_-_179315453 0.16 ENST00000432031.2
protein kinase, interferon-inducible double stranded RNA dependent activator
chrX_+_57618269 0.16 ENST00000374888.1
zinc finger, X-linked, duplicated B
chr16_-_67517716 0.16 ENST00000290953.2
agouti related protein homolog (mouse)
chr14_-_23451467 0.16 ENST00000555074.1
ENST00000361265.4
RP11-298I3.5
ajuba LIM protein
chr2_-_158182410 0.16 ENST00000419116.2
ENST00000410096.1
ermin, ERM-like protein
chrX_+_135570046 0.16 ENST00000370648.3
bombesin-like receptor 3
chr8_+_10530155 0.16 ENST00000521818.1
chromosome 8 open reading frame 74
chr2_-_179315490 0.15 ENST00000487082.1
protein kinase, interferon-inducible double stranded RNA dependent activator
chr5_+_137419581 0.15 ENST00000506684.1
ENST00000504809.1
ENST00000398754.1
wingless-type MMTV integration site family, member 8A
chr20_-_25207370 0.15 ENST00000593352.1
HCG2018895; Uncharacterized protein
chr22_-_31688431 0.15 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
phosphoinositide-3-kinase interacting protein 1
chr5_-_64064508 0.15 ENST00000513458.4
SREK1-interacting protein 1
chr5_+_138629417 0.15 ENST00000510056.1
ENST00000511249.1
ENST00000503811.1
ENST00000511378.1
matrin 3
chr17_+_57642886 0.15 ENST00000251241.4
ENST00000451169.2
ENST00000425628.3
ENST00000584385.1
ENST00000580030.1
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr19_+_49377575 0.15 ENST00000600406.1
protein phosphatase 1, regulatory subunit 15A
chr16_-_3306587 0.15 ENST00000541159.1
ENST00000536379.1
ENST00000219596.1
ENST00000339854.4
Mediterranean fever
chr6_+_39760129 0.15 ENST00000274867.4
dishevelled associated activator of morphogenesis 2
chr2_+_65663812 0.15 ENST00000606978.1
ENST00000377977.3
ENST00000536804.1
AC074391.1
chr15_-_45406385 0.15 ENST00000389039.6
dual oxidase 2
chr18_-_44336998 0.15 ENST00000315087.7
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr1_-_205391178 0.15 ENST00000367153.4
ENST00000367151.2
ENST00000391936.2
ENST00000367149.3
LEM domain containing 1
chr4_-_152149033 0.14 ENST00000514152.1
SH3 domain containing 19
chr12_-_75603202 0.14 ENST00000393288.2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr11_+_6502675 0.14 ENST00000254616.6
ENST00000530751.1
translocase of inner mitochondrial membrane 10 homolog B (yeast)
chrX_+_134887233 0.14 ENST00000443882.1
cancer/testis antigen family 45, member A3
chr7_+_73442102 0.14 ENST00000445912.1
ENST00000252034.7
elastin
chr1_+_111770278 0.14 ENST00000369748.4
chitinase 3-like 2
chr18_+_61445007 0.14 ENST00000447428.1
ENST00000546027.1
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr10_-_28571015 0.14 ENST00000375719.3
ENST00000375732.1
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr1_+_111770232 0.14 ENST00000369744.2
chitinase 3-like 2
chr2_+_9778872 0.14 ENST00000478468.1
RP11-521D12.1
chr10_+_63808970 0.14 ENST00000309334.5
AT rich interactive domain 5B (MRF1-like)
chr1_-_234667504 0.14 ENST00000421207.1
ENST00000435574.1
RP5-855F14.1
chr5_+_102201687 0.14 ENST00000304400.7
peptidylglycine alpha-amidating monooxygenase
chr1_-_154458520 0.13 ENST00000486773.1
Src homology 2 domain containing E
chr7_-_27213893 0.13 ENST00000283921.4
homeobox A10
chr17_+_34136459 0.13 ENST00000588240.1
ENST00000590273.1
ENST00000588441.1
ENST00000587272.1
ENST00000592237.1
ENST00000311979.3
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
chr3_+_111260980 0.13 ENST00000438817.2
CD96 molecule
chr5_-_134735568 0.13 ENST00000510038.1
ENST00000304332.4
H2A histone family, member Y
chr6_+_27107053 0.13 ENST00000354348.2
histone cluster 1, H4i
chr17_-_4463856 0.13 ENST00000574584.1
ENST00000381550.3
ENST00000301395.3
gamma-glutamyltransferase 6
chr13_+_102104952 0.13 ENST00000376180.3
integrin, beta-like 1 (with EGF-like repeat domains)
chr22_-_30162924 0.13 ENST00000344318.3
ENST00000397781.3
zinc finger, matrin-type 5
chr2_+_27237615 0.13 ENST00000458529.1
ENST00000402218.1
microtubule-associated protein, RP/EB family, member 3

Network of associatons between targets according to the STRING database.

First level regulatory network of PGR

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0072229 carbon dioxide transmembrane transport(GO:0035378) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.4 1.2 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.3 1.4 GO:0015917 aminophospholipid transport(GO:0015917) regulation of high-density lipoprotein particle assembly(GO:0090107)
0.3 2.3 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.2 0.7 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.2 0.9 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.2 0.9 GO:0018032 protein amidation(GO:0018032)
0.2 0.6 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.2 0.9 GO:0051585 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.2 0.8 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.1 0.4 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 1.1 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.7 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1 1.2 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.1 0.3 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.1 0.4 GO:0052651 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1 0.4 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1 0.4 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.9 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.1 0.8 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.2 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.1 0.5 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.1 0.2 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.1 0.4 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.1 0.4 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.1 0.3 GO:0060455 negative regulation of histone deacetylation(GO:0031064) negative regulation of gastric acid secretion(GO:0060455)
0.1 0.9 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 1.1 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.2 GO:0003285 septum secundum development(GO:0003285)
0.1 0.2 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 0.2 GO:0035470 apoptotic process involved in outflow tract morphogenesis(GO:0003275) positive regulation of vascular wound healing(GO:0035470) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.1 0.2 GO:0036071 N-glycan fucosylation(GO:0036071)
0.1 0.2 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1 0.8 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.2 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.0 0.2 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.0 0.1 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.1 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0 0.2 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.0 0.3 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.0 0.8 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.7 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.0 0.2 GO:0071469 cellular response to alkaline pH(GO:0071469)
0.0 0.4 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.3 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.1 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.1 GO:1903413 cellular response to bile acid(GO:1903413) response to iron ion starvation(GO:1990641)
0.0 0.5 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.4 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.1 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.2 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 0.5 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.0 0.1 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.0 0.1 GO:0048850 hypophysis morphogenesis(GO:0048850)
0.0 0.1 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.0 0.3 GO:0030091 protein repair(GO:0030091)
0.0 0.2 GO:1904058 positive regulation of sensory perception of pain(GO:1904058)
0.0 0.2 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.9 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.3 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.3 GO:0045023 G0 to G1 transition(GO:0045023)
0.0 0.1 GO:0038188 cholecystokinin signaling pathway(GO:0038188)
0.0 0.0 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 1.3 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.3 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.3 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.2 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.1 GO:0002588 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588) detection of peptidoglycan(GO:0032499)
0.0 0.1 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.1 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 0.7 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.0 GO:0035483 gastric motility(GO:0035482) gastric emptying(GO:0035483) musculoskeletal movement, spinal reflex action(GO:0050883)
0.0 0.1 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.0 0.1 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.3 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.1 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.1 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.1 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.0 0.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.2 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.1 GO:2000909 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0 1.1 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 0.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525) axis elongation involved in somitogenesis(GO:0090245)
0.0 0.2 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.5 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.2 GO:0002003 angiotensin maturation(GO:0002003)
0.0 0.0 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.0 0.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.0 GO:0046104 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0 0.3 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.2 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0020003 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.2 1.2 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.2 0.8 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 1.1 GO:0071953 elastic fiber(GO:0071953)
0.1 0.7 GO:0005577 fibrinogen complex(GO:0005577)
0.1 1.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.6 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.2 GO:1990037 Lewy body core(GO:1990037)
0.0 0.3 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 0.5 GO:0070578 RISC-loading complex(GO:0070578)
0.0 1.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.6 GO:0071564 npBAF complex(GO:0071564)
0.0 0.7 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.7 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.1 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 0.0 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 1.3 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 1.4 GO:0005901 caveola(GO:0005901)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 1.0 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.2 GO:0030128 clathrin coat of endocytic vesicle(GO:0030128)
0.0 2.6 GO:0030427 site of polarized growth(GO:0030427)
0.0 0.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.5 1.4 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.3 1.2 GO:0004948 calcitonin receptor activity(GO:0004948)
0.2 0.9 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.2 1.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.2 0.9 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.2 1.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.4 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 0.8 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.7 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.4 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.1 0.3 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 0.8 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 0.5 GO:0043532 angiostatin binding(GO:0043532)
0.1 0.9 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.3 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 0.2 GO:0070051 fibrinogen binding(GO:0070051)
0.1 0.2 GO:0046921 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.1 0.4 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.5 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.3 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.5 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.3 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.2 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.2 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.2 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.1 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.1 GO:0004608 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.0 0.3 GO:0048039 ubiquinone binding(GO:0048039)
0.0 1.5 GO:0030552 cAMP binding(GO:0030552)
0.0 0.2 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.4 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 0.1 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.0 1.0 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.1 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.1 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:0004951 cholecystokinin receptor activity(GO:0004951)
0.0 1.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.3 GO:0004568 chitinase activity(GO:0004568)
0.0 0.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.2 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.2 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.2 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.2 GO:0004075 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.0 0.0 GO:0004797 thymidine kinase activity(GO:0004797)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 1.3 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.7 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.1 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.0 0.0 GO:0005124 scavenger receptor binding(GO:0005124)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.2 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.1 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.5 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.3 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.6 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.5 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.9 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.9 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.7 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.5 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 1.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.4 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 2.6 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.4 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 1.1 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.6 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 1.3 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.4 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 1.1 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 1.4 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)