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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for PKNOX2

Z-value: 0.48

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Transcription factors associated with PKNOX2

Gene Symbol Gene ID Gene Info
PKNOX2
ENSG00000165495.11 PBX/knotted 1 homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PKNOX2hg19_v2_chr11_+_125034586_125034604-0.145.0e-01Click!

Activity profile of PKNOX2 motif

Sorted Z-values of PKNOX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_157892167 1.25 ENST00000541126.1
PDGFC
platelet derived growth factor C
chr4_-_157892055 1.01 ENST00000422544.2
PDGFC
platelet derived growth factor C
chr4_-_157892498 0.90 ENST00000502773.1
PDGFC
platelet derived growth factor C
chr4_+_128703295 0.60 ENST00000296464.4
ENST00000508549.1
HSPA4L
heat shock 70kDa protein 4-like
chr6_+_138188551 0.56 ENST00000237289.4
ENST00000433680.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr4_-_149365827 0.55 ENST00000344721.4
NR3C2
nuclear receptor subfamily 3, group C, member 2
chr16_+_2880296 0.55 ENST00000571723.1
ZG16B
zymogen granule protein 16B
chr16_+_2880254 0.55 ENST00000570670.1
ZG16B
zymogen granule protein 16B
chrX_-_39923656 0.49 ENST00000413905.1
BCOR
BCL6 corepressor
chr6_-_37225391 0.45 ENST00000356757.2
TMEM217
transmembrane protein 217
chr6_-_101329157 0.43 ENST00000369143.2
ASCC3
activating signal cointegrator 1 complex subunit 3
chr8_+_31496809 0.38 ENST00000518104.1
ENST00000519301.1
NRG1
neuregulin 1
chr12_+_69201923 0.35 ENST00000462284.1
ENST00000258149.5
ENST00000356290.4
ENST00000540827.1
ENST00000428863.2
ENST00000393412.3
MDM2
MDM2 oncogene, E3 ubiquitin protein ligase
chr5_-_58882219 0.33 ENST00000505453.1
ENST00000360047.5
PDE4D
phosphodiesterase 4D, cAMP-specific
chr6_-_101329191 0.31 ENST00000324723.6
ENST00000369162.2
ENST00000522650.1
ASCC3
activating signal cointegrator 1 complex subunit 3
chr1_+_74701062 0.31 ENST00000326637.3
TNNI3K
TNNI3 interacting kinase
chr6_-_11382478 0.28 ENST00000397378.3
ENST00000513989.1
ENST00000508546.1
ENST00000504387.1
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr16_+_2880369 0.28 ENST00000572863.1
ZG16B
zymogen granule protein 16B
chr11_-_111741994 0.27 ENST00000398006.2
ALG9
ALG9, alpha-1,2-mannosyltransferase
chr16_+_2880157 0.26 ENST00000382280.3
ZG16B
zymogen granule protein 16B
chr1_+_181057638 0.26 ENST00000367577.4
IER5
immediate early response 5
chr6_+_31674639 0.24 ENST00000556581.1
ENST00000375832.4
ENST00000503322.1
LY6G6F
MEGT1
lymphocyte antigen 6 complex, locus G6F
HCG43720, isoform CRA_a; Lymphocyte antigen 6 complex locus protein G6f; Megakaryocyte-enhanced gene transcript 1 protein; Uncharacterized protein
chr1_-_54872059 0.24 ENST00000371320.3
SSBP3
single stranded DNA binding protein 3
chr4_+_166300084 0.24 ENST00000402744.4
CPE
carboxypeptidase E
chr9_+_125027127 0.22 ENST00000441707.1
ENST00000373723.5
ENST00000373729.1
MRRF
mitochondrial ribosome recycling factor
chr3_+_52828805 0.21 ENST00000416872.2
ENST00000449956.2
ITIH3
inter-alpha-trypsin inhibitor heavy chain 3
chr10_-_101945771 0.20 ENST00000370408.2
ENST00000407654.3
ERLIN1
ER lipid raft associated 1
chr6_+_37225540 0.20 ENST00000373491.3
TBC1D22B
TBC1 domain family, member 22B
chr6_-_87804815 0.20 ENST00000369582.2
CGA
glycoprotein hormones, alpha polypeptide
chr19_+_41281416 0.19 ENST00000597140.1
MIA
melanoma inhibitory activity
chr2_-_74779744 0.18 ENST00000409249.1
LOXL3
lysyl oxidase-like 3
chr1_+_154966058 0.18 ENST00000392487.1
LENEP
lens epithelial protein
chr7_-_42276612 0.18 ENST00000395925.3
ENST00000437480.1
GLI3
GLI family zinc finger 3
chr2_+_202316392 0.17 ENST00000194530.3
ENST00000392249.2
STRADB
STE20-related kinase adaptor beta
chr3_-_52719810 0.17 ENST00000424867.1
ENST00000394830.3
ENST00000431678.1
ENST00000450271.1
PBRM1
polybromo 1
chr2_+_233271546 0.17 ENST00000295453.3
ALPPL2
alkaline phosphatase, placental-like 2
chr9_-_79307096 0.17 ENST00000376717.2
ENST00000223609.6
ENST00000443509.2
PRUNE2
prune homolog 2 (Drosophila)
chr4_+_169418255 0.16 ENST00000505667.1
ENST00000511948.1
PALLD
palladin, cytoskeletal associated protein
chr5_-_132073111 0.16 ENST00000403231.1
KIF3A
kinesin family member 3A
chr18_+_54318616 0.15 ENST00000254442.3
WDR7
WD repeat domain 7
chr19_+_41281282 0.14 ENST00000263369.3
MIA
melanoma inhibitory activity
chr2_-_74780176 0.13 ENST00000409549.1
LOXL3
lysyl oxidase-like 3
chr11_-_46867780 0.13 ENST00000529230.1
ENST00000415402.1
ENST00000312055.5
CKAP5
cytoskeleton associated protein 5
chr19_+_41281060 0.13 ENST00000594436.1
ENST00000597784.1
MIA
melanoma inhibitory activity
chr1_+_109756523 0.12 ENST00000234677.2
ENST00000369923.4
SARS
seryl-tRNA synthetase
chr20_-_31124186 0.12 ENST00000375678.3
C20orf112
chromosome 20 open reading frame 112
chrX_+_41548259 0.11 ENST00000378138.5
GPR34
G protein-coupled receptor 34
chr2_+_202937972 0.11 ENST00000541917.1
ENST00000295844.3
AC079354.1
uncharacterized protein KIAA2012
chr6_+_150070857 0.11 ENST00000544496.1
PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chrX_+_41548220 0.11 ENST00000378142.4
GPR34
G protein-coupled receptor 34
chr5_-_81046904 0.11 ENST00000515395.1
SSBP2
single-stranded DNA binding protein 2
chr11_+_129245796 0.11 ENST00000281437.4
BARX2
BARX homeobox 2
chr10_+_94608218 0.11 ENST00000371543.1
EXOC6
exocyst complex component 6
chr12_+_62654155 0.11 ENST00000312635.6
ENST00000393654.3
ENST00000549237.1
USP15
ubiquitin specific peptidase 15
chr5_-_81046922 0.10 ENST00000514493.1
ENST00000320672.4
SSBP2
single-stranded DNA binding protein 2
chr4_-_46391805 0.10 ENST00000540012.1
GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr8_-_99837856 0.10 ENST00000518165.1
ENST00000419617.2
STK3
serine/threonine kinase 3
chr1_+_66258846 0.10 ENST00000341517.4
PDE4B
phosphodiesterase 4B, cAMP-specific
chrX_+_16804544 0.10 ENST00000380122.5
ENST00000398155.4
TXLNG
taxilin gamma
chr18_-_67872891 0.10 ENST00000454359.1
ENST00000437017.1
RTTN
rotatin
chr10_+_28822636 0.10 ENST00000442148.1
ENST00000448193.1
WAC
WW domain containing adaptor with coiled-coil
chr9_-_123639304 0.10 ENST00000436309.1
PHF19
PHD finger protein 19
chr5_-_81046841 0.09 ENST00000509013.2
ENST00000505980.1
ENST00000509053.1
SSBP2
single-stranded DNA binding protein 2
chr10_+_94608245 0.09 ENST00000443748.2
ENST00000260762.6
EXOC6
exocyst complex component 6
chr22_+_50946645 0.09 ENST00000420993.2
ENST00000395698.3
ENST00000395701.3
ENST00000523045.1
ENST00000299821.11
NCAPH2
non-SMC condensin II complex, subunit H2
chr2_+_219524473 0.09 ENST00000439945.1
ENST00000431802.1
BCS1L
BC1 (ubiquinol-cytochrome c reductase) synthesis-like
chr21_-_32931290 0.08 ENST00000286827.3
TIAM1
T-cell lymphoma invasion and metastasis 1
chr19_+_10828795 0.08 ENST00000389253.4
ENST00000355667.6
ENST00000408974.4
DNM2
dynamin 2
chr3_-_52001448 0.08 ENST00000461554.1
ENST00000395013.3
ENST00000428823.2
ENST00000483411.1
ENST00000461544.1
ENST00000355852.2
PCBP4
poly(rC) binding protein 4
chr5_+_125758865 0.08 ENST00000542322.1
ENST00000544396.1
GRAMD3
GRAM domain containing 3
chr14_-_21994525 0.08 ENST00000538754.1
SALL2
spalt-like transcription factor 2
chr16_+_88636789 0.08 ENST00000301011.5
ENST00000452588.2
ZC3H18
zinc finger CCCH-type containing 18
chr20_-_3065362 0.08 ENST00000380293.3
AVP
arginine vasopressin
chr18_+_3449821 0.08 ENST00000407501.2
ENST00000405385.3
ENST00000546979.1
TGIF1
TGFB-induced factor homeobox 1
chr5_+_125758813 0.07 ENST00000285689.3
ENST00000515200.1
GRAMD3
GRAM domain containing 3
chr18_+_3449695 0.07 ENST00000343820.5
TGIF1
TGFB-induced factor homeobox 1
chrX_-_77225135 0.07 ENST00000458128.1
PGAM4
phosphoglycerate mutase family member 4
chr19_+_10828724 0.07 ENST00000585892.1
ENST00000314646.5
ENST00000359692.6
DNM2
dynamin 2
chr1_+_145549203 0.07 ENST00000355594.4
ENST00000544626.1
ANKRD35
ankyrin repeat domain 35
chr11_+_45743858 0.07 ENST00000532307.1
CTD-2210P24.1
CTD-2210P24.1
chr11_+_12132117 0.07 ENST00000256194.4
MICAL2
microtubule associated monooxygenase, calponin and LIM domain containing 2
chr3_-_127541679 0.07 ENST00000265052.5
MGLL
monoglyceride lipase
chr11_+_45743931 0.07 ENST00000530051.1
CTD-2210P24.1
CTD-2210P24.1
chr18_+_54318566 0.07 ENST00000589935.1
ENST00000357574.3
WDR7
WD repeat domain 7
chr5_-_127873896 0.07 ENST00000502468.1
FBN2
fibrillin 2
chr4_+_140222609 0.06 ENST00000296543.5
ENST00000398947.1
NAA15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr1_-_179198702 0.06 ENST00000502732.1
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chrX_-_128788914 0.06 ENST00000429967.1
ENST00000307484.6
APLN
apelin
chr13_+_33160553 0.06 ENST00000315596.10
PDS5B
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr19_-_39735646 0.06 ENST00000413851.2
IFNL3
interferon, lambda 3
chr6_+_150070831 0.06 ENST00000367380.5
PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr16_-_1275257 0.06 ENST00000234798.4
TPSG1
tryptase gamma 1
chr2_-_179672142 0.05 ENST00000342992.6
ENST00000360870.5
ENST00000460472.2
ENST00000589042.1
ENST00000591111.1
ENST00000342175.6
ENST00000359218.5
TTN
titin
chr4_-_46391367 0.05 ENST00000503806.1
ENST00000356504.1
ENST00000514090.1
ENST00000506961.1
GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr11_+_120207787 0.05 ENST00000397843.2
ENST00000356641.3
ARHGEF12
Rho guanine nucleotide exchange factor (GEF) 12
chr1_-_179112173 0.05 ENST00000408940.3
ENST00000504405.1
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr11_-_101000445 0.05 ENST00000534013.1
PGR
progesterone receptor
chr2_+_191208196 0.05 ENST00000392329.2
ENST00000322522.4
ENST00000430311.1
ENST00000541441.1
INPP1
inositol polyphosphate-1-phosphatase
chr1_-_35658736 0.05 ENST00000357214.5
SFPQ
splicing factor proline/glutamine-rich
chr2_-_211179883 0.05 ENST00000352451.3
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr17_-_40337470 0.05 ENST00000293330.1
HCRT
hypocretin (orexin) neuropeptide precursor
chr7_-_104909435 0.05 ENST00000357311.3
SRPK2
SRSF protein kinase 2
chr11_-_74660159 0.04 ENST00000527087.1
ENST00000321448.8
ENST00000340360.6
XRRA1
X-ray radiation resistance associated 1
chr9_+_87285539 0.04 ENST00000359847.3
NTRK2
neurotrophic tyrosine kinase, receptor, type 2
chr17_+_38474489 0.04 ENST00000394089.2
ENST00000425707.3
RARA
retinoic acid receptor, alpha
chr10_+_51565188 0.04 ENST00000430396.2
ENST00000374087.4
ENST00000414907.2
NCOA4
nuclear receptor coactivator 4
chr15_-_61521495 0.04 ENST00000335670.6
RORA
RAR-related orphan receptor A
chr16_+_1756162 0.04 ENST00000250894.4
ENST00000356010.5
MAPK8IP3
mitogen-activated protein kinase 8 interacting protein 3
chr20_-_39946237 0.03 ENST00000441102.2
ENST00000559234.1
ZHX3
zinc fingers and homeoboxes 3
chr5_+_118407053 0.03 ENST00000311085.8
ENST00000539542.1
DMXL1
Dmx-like 1
chr3_-_101395936 0.03 ENST00000461821.1
ZBTB11
zinc finger and BTB domain containing 11
chr1_+_161736072 0.03 ENST00000367942.3
ATF6
activating transcription factor 6
chr4_+_169418195 0.03 ENST00000261509.6
ENST00000335742.7
PALLD
palladin, cytoskeletal associated protein
chr11_-_59383617 0.03 ENST00000263847.1
OSBP
oxysterol binding protein
chr19_+_7733929 0.03 ENST00000221515.2
RETN
resistin
chr3_-_127541194 0.03 ENST00000453507.2
MGLL
monoglyceride lipase
chr17_+_68071389 0.03 ENST00000283936.1
ENST00000392671.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr19_+_57050317 0.03 ENST00000301318.3
ENST00000591844.1
ZFP28
ZFP28 zinc finger protein
chr7_-_156803329 0.03 ENST00000252971.6
MNX1
motor neuron and pancreas homeobox 1
chr10_+_70661014 0.02 ENST00000373585.3
DDX50
DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
chr5_+_78985673 0.02 ENST00000446378.2
CMYA5
cardiomyopathy associated 5
chr2_+_219081817 0.02 ENST00000315717.5
ENST00000420104.1
ENST00000295685.10
ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr11_-_132813566 0.02 ENST00000331898.7
OPCML
opioid binding protein/cell adhesion molecule-like
chr16_+_57481349 0.02 ENST00000262507.6
ENST00000565964.1
COQ9
coenzyme Q9
chr6_-_149867122 0.02 ENST00000253329.2
PPIL4
peptidylprolyl isomerase (cyclophilin)-like 4
chr7_-_137028498 0.02 ENST00000393083.2
PTN
pleiotrophin
chr17_+_68071458 0.02 ENST00000589377.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr7_-_137028534 0.02 ENST00000348225.2
PTN
pleiotrophin
chr6_+_108881012 0.02 ENST00000343882.6
FOXO3
forkhead box O3
chr17_-_4046257 0.02 ENST00000381638.2
ZZEF1
zinc finger, ZZ-type with EF-hand domain 1
chr2_-_242842587 0.01 ENST00000404031.1
AC131097.4
Protein LOC285095
chr6_-_114664180 0.01 ENST00000312719.5
HS3ST5
heparan sulfate (glucosamine) 3-O-sulfotransferase 5
chr11_+_74660278 0.01 ENST00000263672.6
ENST00000530257.1
ENST00000526361.1
ENST00000532972.1
SPCS2
signal peptidase complex subunit 2 homolog (S. cerevisiae)
chr16_+_50776021 0.01 ENST00000566679.2
ENST00000564634.1
ENST00000398568.2
CYLD
cylindromatosis (turban tumor syndrome)
chr8_-_57123815 0.01 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
PLAG1
pleiomorphic adenoma gene 1
chr17_-_42452063 0.01 ENST00000588098.1
ITGA2B
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
chr9_-_73477826 0.01 ENST00000396285.1
ENST00000396292.4
ENST00000396280.5
ENST00000358082.3
ENST00000408909.2
ENST00000377097.3
TRPM3
transient receptor potential cation channel, subfamily M, member 3
chr3_+_52719936 0.01 ENST00000418458.1
ENST00000394799.2
GNL3
guanine nucleotide binding protein-like 3 (nucleolar)
chr22_+_30279144 0.01 ENST00000401950.2
ENST00000333027.3
ENST00000445401.1
ENST00000323630.5
ENST00000351488.3
MTMR3
myotubularin related protein 3
chr12_-_91398796 0.01 ENST00000261172.3
ENST00000551767.1
EPYC
epiphycan
chr18_-_54305658 0.00 ENST00000586262.1
ENST00000217515.6
TXNL1
thioredoxin-like 1
chr19_+_36142147 0.00 ENST00000590618.1
COX6B1
cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)
chr2_-_202316260 0.00 ENST00000332624.3
TRAK2
trafficking protein, kinesin binding 2

Network of associatons between targets according to the STRING database.

First level regulatory network of PKNOX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0071947 B-1 B cell homeostasis(GO:0001922) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.2 0.5 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.1 3.5 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1 0.4 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.1 0.3 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.1 0.2 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.0 0.2 GO:0030070 insulin processing(GO:0030070)
0.0 0.6 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.2 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.1 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.3 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.1 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.2 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.2 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.1 GO:0002125 maternal aggressive behavior(GO:0002125)
0.0 0.1 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.0 0.1 GO:0019417 sulfur oxidation(GO:0019417)
0.0 0.1 GO:0043396 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) regulation of G-protein coupled receptor internalization(GO:1904020)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.2 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 1.6 GO:0001895 retina homeostasis(GO:0001895)
0.0 0.2 GO:0030091 protein repair(GO:0030091)
0.0 0.2 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.3 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.1 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.1 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0 0.1 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.1 GO:1903977 NMDA selective glutamate receptor signaling pathway(GO:0098989) positive regulation of glial cell migration(GO:1903977)
0.0 0.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.0 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.0 0.1 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.0 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.2 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.0 GO:0043291 RAVE complex(GO:0043291)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.1 3.2 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 0.3 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.1 0.7 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.1 0.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.4 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.6 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 0.3 GO:0031013 troponin I binding(GO:0031013)
0.0 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.3 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.1 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.1 GO:0031893 vasopressin receptor binding(GO:0031893)
0.0 0.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.2 GO:0008503 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.6 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.4 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.4 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.6 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway