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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for POU1F1

Z-value: 0.49

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Transcription factors associated with POU1F1

Gene Symbol Gene ID Gene Info
ENSG00000064835.6 POU class 1 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU1F1hg19_v2_chr3_-_87325612_873256540.116.0e-01Click!

Activity profile of POU1F1 motif

Sorted Z-values of POU1F1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_67418047 1.38 ENST00000540846.2
SMAD family member 3
chr2_+_161993465 1.26 ENST00000457476.1
TRAF family member-associated NFKB activator
chr11_-_102651343 1.18 ENST00000279441.4
ENST00000539681.1
matrix metallopeptidase 10 (stromelysin 2)
chr2_+_152214098 1.06 ENST00000243347.3
tumor necrosis factor, alpha-induced protein 6
chr2_+_161993412 1.01 ENST00000259075.2
ENST00000432002.1
TRAF family member-associated NFKB activator
chr10_+_91152303 0.97 ENST00000371804.3
interferon-induced protein with tetratricopeptide repeats 1
chr5_+_55149150 0.83 ENST00000297015.3
interleukin 31 receptor A
chr9_+_12693336 0.82 ENST00000381137.2
ENST00000388918.5
tyrosinase-related protein 1
chr10_-_49860525 0.58 ENST00000435790.2
Rho GTPase activating protein 22
chr7_-_14026063 0.54 ENST00000443608.1
ENST00000438956.1
ets variant 1
chr11_+_35201826 0.53 ENST00000531873.1
CD44 molecule (Indian blood group)
chr22_+_23487513 0.53 ENST00000263116.2
ENST00000341989.4
RAB36, member RAS oncogene family
chr19_+_54466179 0.53 ENST00000270458.2
calcium channel, voltage-dependent, gamma subunit 8
chr17_-_5321549 0.49 ENST00000572809.1
nucleoporin 88kDa
chr6_+_114178512 0.49 ENST00000368635.4
myristoylated alanine-rich protein kinase C substrate
chr2_+_103035102 0.49 ENST00000264260.2
interleukin 18 receptor accessory protein
chr3_-_191000172 0.49 ENST00000427544.2
urotensin 2B
chr4_-_120243545 0.47 ENST00000274024.3
fatty acid binding protein 2, intestinal
chr11_+_5710919 0.40 ENST00000379965.3
ENST00000425490.1
tripartite motif containing 22
chr2_-_231989808 0.38 ENST00000258400.3
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr17_+_29664830 0.37 ENST00000444181.2
ENST00000417592.2
neurofibromin 1
chr9_-_85882145 0.37 ENST00000328788.1
FERM domain containing 3
chr10_-_14050522 0.37 ENST00000342409.2
FERM domain containing 4A
chr17_+_76494911 0.37 ENST00000598378.1
DNAH17 antisense RNA 1
chr2_-_220264703 0.35 ENST00000519905.1
ENST00000523282.1
ENST00000434339.1
ENST00000457935.1
aspartyl aminopeptidase
chr1_+_8378140 0.33 ENST00000377479.2
solute carrier family 45, member 1
chr12_-_11150474 0.33 ENST00000538986.1
taste receptor, type 2, member 20
chr4_+_74301880 0.32 ENST00000395792.2
ENST00000226359.2
alpha-fetoprotein
chr4_+_71263599 0.32 ENST00000399575.2
proline rich, lacrimal 1
chr1_+_87012753 0.31 ENST00000370563.3
chloride channel accessory 4
chr7_-_139763521 0.31 ENST00000263549.3
poly (ADP-ribose) polymerase family, member 12
chr7_+_134528635 0.30 ENST00000445569.2
caldesmon 1
chr3_-_108248169 0.28 ENST00000273353.3
myosin, heavy chain 15
chr17_-_39165366 0.28 ENST00000391588.1
keratin associated protein 3-1
chr5_-_88119580 0.28 ENST00000539796.1
myocyte enhancer factor 2C
chr19_+_572543 0.27 ENST00000333511.3
ENST00000573216.1
ENST00000353555.4
basigin (Ok blood group)
chr14_-_101295407 0.26 ENST00000596284.1
AL117190.2
chr3_-_27498235 0.26 ENST00000295736.5
ENST00000428386.1
ENST00000428179.1
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr4_+_96012614 0.26 ENST00000264568.4
bone morphogenetic protein receptor, type IB
chr5_+_111755280 0.26 ENST00000600409.1
EPB41L4A antisense RNA 2 (head to head)
chr3_+_52245458 0.26 ENST00000459884.1
aminolevulinate, delta-, synthase 1
chr7_+_13141097 0.26 ENST00000411542.1
AC011288.2
chr5_+_173472607 0.25 ENST00000303177.3
ENST00000519867.1
Neuron-specific protein family member 2
chr9_-_33473882 0.25 ENST00000455041.2
ENST00000353159.2
ENST00000297990.4
ENST00000379471.2
nucleolar protein 6 (RNA-associated)
chr10_-_50396425 0.25 ENST00000374148.1
chromosome 10 open reading frame 128
chr6_+_26440700 0.24 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
butyrophilin, subfamily 3, member A3
chr16_-_28634874 0.24 ENST00000395609.1
ENST00000350842.4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr4_+_86525299 0.23 ENST00000512201.1
Rho GTPase activating protein 24
chr16_-_70835034 0.23 ENST00000261776.5
Vac14 homolog (S. cerevisiae)
chr6_+_26365443 0.23 ENST00000527422.1
ENST00000356386.2
ENST00000396934.3
ENST00000377708.2
ENST00000396948.1
ENST00000508906.2
butyrophilin, subfamily 3, member A2
chr10_-_27529486 0.23 ENST00000375888.1
acyl-CoA binding domain containing 5
chr5_-_93077293 0.22 ENST00000510627.4
POU domain class 5, transcription factor 2
chr3_+_159943362 0.22 ENST00000326474.3
chromosome 3 open reading frame 80
chr8_+_30244580 0.22 ENST00000523115.1
ENST00000519647.1
RNA binding protein with multiple splicing
chr1_-_247921982 0.22 ENST00000408896.2
olfactory receptor, family 1, subfamily C, member 1
chr6_-_89927151 0.22 ENST00000454853.2
gamma-aminobutyric acid (GABA) A receptor, rho 1
chrX_-_11308598 0.21 ENST00000380717.3
Rho GTPase activating protein 6
chr10_+_53806501 0.21 ENST00000373975.2
protein kinase, cGMP-dependent, type I
chr1_-_67266939 0.20 ENST00000304526.2
insulin-like 5
chr4_+_186990298 0.20 ENST00000296795.3
ENST00000513189.1
toll-like receptor 3
chr15_-_75748115 0.20 ENST00000360439.4
SIN3 transcription regulator family member A
chr17_-_2996290 0.20 ENST00000331459.1
olfactory receptor, family 1, subfamily D, member 2
chr4_-_122085469 0.19 ENST00000057513.3
TNFAIP3 interacting protein 3
chr3_-_108476231 0.19 ENST00000295755.6
resistin like beta
chr19_+_19144384 0.19 ENST00000392335.2
ENST00000535612.1
ENST00000537263.1
ENST00000540707.1
ENST00000541725.1
ENST00000269932.6
ENST00000546344.1
ENST00000540792.1
ENST00000536098.1
ENST00000541898.1
ENST00000543877.1
armadillo repeat containing 6
chr7_-_87342564 0.18 ENST00000265724.3
ENST00000416177.1
ATP-binding cassette, sub-family B (MDR/TAP), member 1
chrX_-_77225135 0.18 ENST00000458128.1
phosphoglycerate mutase family member 4
chrX_+_84258832 0.17 ENST00000373173.2
apolipoprotein O-like
chr3_-_190167571 0.17 ENST00000354905.2
transmembrane protein 207
chr15_+_84115868 0.17 ENST00000427482.2
SH3-domain GRB2-like 3
chr19_-_22193731 0.17 ENST00000601773.1
ENST00000397126.4
ENST00000601993.1
ENST00000599916.1
zinc finger protein 208
chr22_-_43010928 0.16 ENST00000348657.2
ENST00000252115.5
polymerase (DNA-directed), delta interacting protein 3
chr15_+_75970672 0.16 ENST00000435356.1
Uncharacterized protein; cDNA FLJ12988 fis, clone NT2RP3000080
chr9_-_95056010 0.16 ENST00000443024.2
isoleucyl-tRNA synthetase
chr19_-_56826157 0.16 ENST00000592509.1
ENST00000592679.1
ENST00000588442.1
ENST00000593106.1
ENST00000587492.1
ENST00000254165.3
zinc finger and SCAN domain containing 5A
chr4_-_159956333 0.16 ENST00000434826.2
chromosome 4 open reading frame 45
chr12_+_12510352 0.16 ENST00000298571.6
loss of heterozygosity, 12, chromosomal region 1
chr4_+_175839506 0.16 ENST00000505141.1
ENST00000359240.3
ENST00000445694.1
ADAM metallopeptidase domain 29
chr4_+_3344141 0.15 ENST00000306648.7
regulator of G-protein signaling 12
chr3_+_160939050 0.15 ENST00000493066.1
ENST00000351193.2
ENST00000472947.1
ENST00000463518.1
NMD3 ribosome export adaptor
chr1_+_111682058 0.15 ENST00000545121.1
choline/ethanolamine phosphotransferase 1
chr1_+_117963209 0.15 ENST00000449370.2
mannosidase, alpha, class 1A, member 2
chr12_-_95510743 0.15 ENST00000551521.1
FYVE, RhoGEF and PH domain containing 6
chrY_-_6740649 0.15 ENST00000383036.1
ENST00000383037.4
amelogenin, Y-linked
chr12_-_86650045 0.15 ENST00000604798.1
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr21_-_27423339 0.15 ENST00000415997.1
amyloid beta (A4) precursor protein
chr5_+_140762268 0.15 ENST00000518325.1
protocadherin gamma subfamily A, 7
chr8_-_38008783 0.14 ENST00000276449.4
steroidogenic acute regulatory protein
chr4_-_103746683 0.14 ENST00000504211.1
ENST00000508476.1
ubiquitin-conjugating enzyme E2D 3
chr4_+_175839551 0.14 ENST00000404450.4
ENST00000514159.1
ADAM metallopeptidase domain 29
chr11_-_104827425 0.14 ENST00000393150.3
caspase 4, apoptosis-related cysteine peptidase
chr9_-_215744 0.14 ENST00000382387.2
chromosome 9 open reading frame 66
chr8_+_36641842 0.14 ENST00000523973.1
ENST00000399881.3
potassium channel, subfamily U, member 1
chr11_+_2405833 0.14 ENST00000527343.1
ENST00000464784.2
CD81 molecule
chr19_+_52873166 0.14 ENST00000424032.2
ENST00000600321.1
ENST00000344085.5
ENST00000597976.1
ENST00000422689.2
zinc finger protein 880
chr17_-_64225508 0.14 ENST00000205948.6
apolipoprotein H (beta-2-glycoprotein I)
chr4_-_122854612 0.13 ENST00000264811.5
transient receptor potential cation channel, subfamily C, member 3
chr18_+_29027696 0.13 ENST00000257189.4
desmoglein 3
chr11_-_107729887 0.13 ENST00000525815.1
solute carrier family 35, member F2
chr21_-_15583165 0.13 ENST00000536861.1
lipase, member I
chr1_+_234765057 0.13 ENST00000429269.1
long intergenic non-protein coding RNA 184
chr15_+_64680003 0.13 ENST00000261884.3
thyroid hormone receptor interactor 4
chr9_+_111624577 0.13 ENST00000333999.3
actin-like 7A
chr6_-_136788001 0.13 ENST00000544465.1
microtubule-associated protein 7
chr1_-_13390765 0.13 ENST00000357367.2
PRAME family member 8
chr12_-_52761262 0.12 ENST00000257901.3
keratin 85
chr7_-_111032971 0.12 ENST00000450877.1
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr18_+_45778672 0.12 ENST00000600091.1
HCG1818186; Uncharacterized protein
chrX_+_70503433 0.12 ENST00000276079.8
ENST00000373856.3
ENST00000373841.1
ENST00000420903.1
non-POU domain containing, octamer-binding
chr20_+_59654146 0.12 ENST00000441660.1
RP5-827L5.1
chr18_+_21269404 0.12 ENST00000313654.9
laminin, alpha 3
chr7_+_129984630 0.12 ENST00000355388.3
ENST00000497503.1
ENST00000463587.1
ENST00000461828.1
ENST00000494311.1
ENST00000466363.2
ENST00000485477.1
ENST00000431780.2
ENST00000474905.1
carboxypeptidase A5
chr17_+_6918354 0.12 ENST00000552775.1
chromosome 17 open reading frame 49
chr6_-_134861089 0.12 ENST00000606039.1
RP11-557H15.4
chr3_+_130650738 0.12 ENST00000504612.1
ATPase, Ca++ transporting, type 2C, member 1
chr6_+_29555683 0.12 ENST00000383640.2
olfactory receptor, family 2, subfamily H, member 2
chr6_-_152639479 0.12 ENST00000356820.4
spectrin repeat containing, nuclear envelope 1
chr5_+_156696362 0.12 ENST00000377576.3
cytoplasmic FMR1 interacting protein 2
chr9_-_95055956 0.12 ENST00000375629.3
ENST00000447699.2
ENST00000375643.3
ENST00000395554.3
isoleucyl-tRNA synthetase
chr1_-_183560011 0.12 ENST00000367536.1
neutrophil cytosolic factor 2
chr20_-_43589109 0.12 ENST00000372813.3
translocase of outer mitochondrial membrane 34
chr10_+_94352956 0.12 ENST00000260731.3
kinesin family member 11
chr1_-_183559693 0.12 ENST00000367535.3
ENST00000413720.1
ENST00000418089.1
neutrophil cytosolic factor 2
chr4_+_151503077 0.11 ENST00000317605.4
mab-21-like 2 (C. elegans)
chr1_+_112938803 0.11 ENST00000271277.6
CTTNBP2 N-terminal like
chr2_+_223162866 0.11 ENST00000295226.1
coiled-coil domain containing 140
chr1_-_182921119 0.11 ENST00000423786.1
SHC SH2-domain binding protein 1-like
chr7_+_99425633 0.11 ENST00000354829.2
ENST00000421837.2
ENST00000417625.1
ENST00000342499.4
ENST00000444905.1
ENST00000415413.1
ENST00000312017.5
ENST00000222382.5
cytochrome P450, family 3, subfamily A, polypeptide 43
chrX_+_83116142 0.11 ENST00000329312.4
cylicin, basic protein of sperm head cytoskeleton 1
chr18_+_21269556 0.11 ENST00000399516.3
laminin, alpha 3
chr12_+_93096759 0.11 ENST00000544406.2
chromosome 12 open reading frame 74
chr6_-_109702885 0.11 ENST00000504373.1
CD164 molecule, sialomucin
chr8_-_59412717 0.10 ENST00000301645.3
cytochrome P450, family 7, subfamily A, polypeptide 1
chr12_+_69753448 0.10 ENST00000247843.2
ENST00000548020.1
ENST00000549685.1
ENST00000552955.1
YEATS domain containing 4
chr11_-_58612168 0.10 ENST00000287275.1
glycine-N-acyltransferase-like 2
chr12_-_10959892 0.10 ENST00000240615.2
taste receptor, type 2, member 8
chr20_+_5987890 0.10 ENST00000378868.4
cardiolipin synthase 1
chr5_+_119867159 0.10 ENST00000505123.1
proline rich 16
chrX_-_32173579 0.09 ENST00000359836.1
ENST00000343523.2
ENST00000378707.3
ENST00000541735.1
ENST00000474231.1
dystrophin
chr1_+_152943122 0.09 ENST00000328051.2
small proline-rich protein 4
chr11_-_22647350 0.09 ENST00000327470.3
Fanconi anemia, complementation group F
chr2_-_190044480 0.09 ENST00000374866.3
collagen, type V, alpha 2
chr10_+_97759848 0.09 ENST00000424464.1
ENST00000410012.2
ENST00000344386.3
coiled-coil and C2 domain containing 2B
chr4_+_119809984 0.09 ENST00000307142.4
ENST00000448416.2
ENST00000429713.2
synaptopodin 2
chr14_-_25078864 0.09 ENST00000216338.4
ENST00000557220.2
ENST00000382548.4
granzyme H (cathepsin G-like 2, protein h-CCPX)
chr2_+_58655461 0.09 ENST00000429095.1
ENST00000429664.1
ENST00000452840.1
long intergenic non-protein coding RNA 1122
chr5_+_60933634 0.09 ENST00000505642.1
chromosome 5 open reading frame 64
chr1_+_119957554 0.09 ENST00000543831.1
ENST00000433745.1
ENST00000369416.3
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
chr17_+_1944790 0.09 ENST00000575162.1
diphthamide biosynthesis 1
chr17_+_6918093 0.09 ENST00000439424.2
chromosome 17 open reading frame 49
chr12_+_93096619 0.09 ENST00000397833.3
chromosome 12 open reading frame 74
chr2_-_99871570 0.09 ENST00000333017.2
ENST00000409679.1
ENST00000423306.1
lysozyme G-like 2
chr12_-_25150373 0.09 ENST00000549828.1
chromosome 12 open reading frame 77
chr4_-_138453559 0.09 ENST00000511115.1
protocadherin 18
chr7_-_141957847 0.08 ENST00000552471.1
ENST00000547058.2
protease, serine, 58
chr5_+_140593509 0.08 ENST00000341948.4
protocadherin beta 13
chr1_-_53608289 0.08 ENST00000371491.4
solute carrier family 1 (glutamate transporter), member 7
chr10_-_52645379 0.08 ENST00000395489.2
APOBEC1 complementation factor
chr11_-_13517565 0.08 ENST00000282091.1
ENST00000529816.1
parathyroid hormone
chr3_+_132843652 0.08 ENST00000508711.1
transmembrane protein 108
chr10_+_62538089 0.08 ENST00000519078.2
ENST00000395284.3
ENST00000316629.4
cyclin-dependent kinase 1
chr12_+_25205666 0.08 ENST00000547044.1
lymphoid-restricted membrane protein
chr12_+_26348429 0.08 ENST00000242729.2
sarcospan
chr6_-_49604545 0.08 ENST00000371175.4
ENST00000229810.7
Rh-associated glycoprotein
chr12_-_42631529 0.08 ENST00000548917.1
YY1 associated factor 2
chr5_-_36301984 0.07 ENST00000502994.1
ENST00000515759.1
ENST00000296604.3
RAN binding protein 3-like
chr1_+_192127578 0.07 ENST00000367460.3
regulator of G-protein signaling 18
chr21_-_15918618 0.07 ENST00000400564.1
ENST00000400566.1
SAM domain, SH3 domain and nuclear localization signals 1
chr21_-_43735628 0.07 ENST00000291525.10
ENST00000518498.1
trefoil factor 3 (intestinal)
chr20_+_5986756 0.07 ENST00000452938.1
cardiolipin synthase 1
chr13_-_70682590 0.07 ENST00000377844.4
kelch-like family member 1
chr3_-_160823040 0.07 ENST00000484127.1
ENST00000492353.1
ENST00000473142.1
ENST00000468268.1
ENST00000460353.1
ENST00000320474.4
ENST00000392781.2
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr12_+_26348246 0.07 ENST00000422622.2
sarcospan
chr7_+_134671234 0.07 ENST00000436302.2
ENST00000359383.3
ENST00000458078.1
ENST00000435976.2
ENST00000455283.2
ATP/GTP binding protein-like 3
chr10_+_695888 0.07 ENST00000441152.2
proline rich 26
chr9_-_28670283 0.07 ENST00000379992.2
leucine rich repeat and Ig domain containing 2
chr4_+_37455536 0.07 ENST00000381980.4
ENST00000508175.1
chromosome 4 open reading frame 19
chr2_-_169887827 0.07 ENST00000263817.6
ATP-binding cassette, sub-family B (MDR/TAP), member 11
chrX_-_106243451 0.07 ENST00000355610.4
ENST00000535534.1
MORC family CW-type zinc finger 4
chr1_+_149754227 0.07 ENST00000444948.1
ENST00000369168.4
Fc fragment of IgG, high affinity Ia, receptor (CD64)
chr6_-_49712147 0.07 ENST00000433368.2
ENST00000354620.4
cysteine-rich secretory protein 3
chr4_-_46911248 0.07 ENST00000355591.3
ENST00000505102.1
cytochrome c oxidase subunit VIIb2
chr11_-_26593677 0.06 ENST00000527569.1
mucin 15, cell surface associated
chr4_+_119810134 0.06 ENST00000434046.2
synaptopodin 2
chr17_-_72772462 0.06 ENST00000582870.1
ENST00000581136.1
ENST00000357814.3
ENST00000579218.1
ENST00000583476.1
ENST00000580301.1
ENST00000583757.1
ENST00000582524.1
N-acetyltransferase 9 (GCN5-related, putative)
chr10_-_28623368 0.06 ENST00000441595.2
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr1_-_154580616 0.06 ENST00000368474.4
adenosine deaminase, RNA-specific
chrX_-_102531717 0.06 ENST00000372680.1
transcription elongation factor A (SII)-like 5
chr6_-_49712123 0.06 ENST00000263045.4
cysteine-rich secretory protein 3
chr1_+_158323755 0.06 ENST00000368157.1
ENST00000368156.1
ENST00000368155.3
ENST00000368154.1
ENST00000368160.3
ENST00000368161.3
CD1e molecule
chr16_+_28565230 0.06 ENST00000317058.3
coiled-coil domain containing 101
chr6_+_131958436 0.06 ENST00000357639.3
ENST00000543135.1
ENST00000427148.2
ENST00000358229.5
ectonucleotide pyrophosphatase/phosphodiesterase 3
chrX_-_102943022 0.06 ENST00000433176.2
mortality factor 4 like 2
chr20_+_30697298 0.06 ENST00000398022.2
transmembrane 9 superfamily protein member 4
chr14_-_106668095 0.06 ENST00000390606.2
immunoglobulin heavy variable 3-20
chr5_+_115177178 0.06 ENST00000316788.7
adaptor-related protein complex 3, sigma 1 subunit
chr1_-_197036364 0.06 ENST00000367412.1
coagulation factor XIII, B polypeptide
chr13_-_81801115 0.06 ENST00000567258.1
long intergenic non-protein coding RNA 564
chr2_-_26700900 0.06 ENST00000338581.6
ENST00000339598.3
ENST00000402415.3
otoferlin
chr9_-_21351377 0.06 ENST00000380210.1
interferon, alpha 6

Network of associatons between targets according to the STRING database.

First level regulatory network of POU1F1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.3 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.3 1.0 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.3 1.4 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.4 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.1 0.3 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.1 0.4 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1 0.8 GO:1900378 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.1 0.6 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.1 0.3 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.5 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 0.3 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 1.5 GO:0030728 ovulation(GO:0030728)
0.0 0.8 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.2 GO:0034343 microglial cell activation involved in immune response(GO:0002282) type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.2 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.1 GO:0070859 dibenzo-p-dioxin metabolic process(GO:0018894) positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.0 0.2 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.0 GO:0009441 glycolate metabolic process(GO:0009441)
0.0 0.1 GO:0043128 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.1 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.1 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.0 0.2 GO:1904386 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.0 0.2 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.0 0.1 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.3 GO:0046689 response to mercury ion(GO:0046689)
0.0 0.5 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.1 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.0 0.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.5 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.2 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.5 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.0 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.0 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.0 0.0 GO:0042138 meiotic DNA double-strand break processing(GO:0000706) meiotic DNA double-strand break formation(GO:0042138) double-strand break repair involved in meiotic recombination(GO:1990918)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.2 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 1.2 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.0 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.1 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
0.0 0.1 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.0 0.1 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.1 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.2 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.2 0.5 GO:0042585 germinal vesicle(GO:0042585)
0.1 0.5 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.8 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.1 GO:0033150 cytoskeletal calyx(GO:0033150) acrosomal matrix(GO:0043159)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.2 GO:0032010 phagolysosome(GO:0032010)
0.0 0.2 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.2 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:1990812 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.0 0.1 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.0 0.1 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 1.2 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.3 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 1.4 GO:0043657 host(GO:0018995) host cell(GO:0043657)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.1 GO:0072687 meiotic spindle(GO:0072687)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.3 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.3 1.4 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.3 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.1 0.2 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 0.2 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.0 1.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.1 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.0 0.2 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.2 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.0 0.4 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.2 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.1 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.3 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.1 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.1 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.1 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.3 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.0 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.0 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 1.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.0 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 1.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.2 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.5 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.4 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.2 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 1.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.5 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels