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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for POU2F2_POU3F1

Z-value: 0.61

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Transcription factors associated with POU2F2_POU3F1

Gene Symbol Gene ID Gene Info
ENSG00000028277.16 POU class 2 homeobox 2
ENSG00000185668.5 POU class 3 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU2F2hg19_v2_chr19_-_42636617_426366320.262.2e-01Click!
POU3F1hg19_v2_chr1_-_38512450_385124740.067.6e-01Click!

Activity profile of POU2F2_POU3F1 motif

Sorted Z-values of POU2F2_POU3F1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_106610852 0.98 ENST00000390603.2
immunoglobulin heavy variable 3-15
chr14_-_106994333 0.89 ENST00000390624.2
immunoglobulin heavy variable 3-48
chr6_-_10415470 0.87 ENST00000379604.2
ENST00000379613.3
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr6_+_31588478 0.84 ENST00000376007.4
ENST00000376033.2
proline-rich coiled-coil 2A
chr17_+_38171681 0.78 ENST00000225474.2
ENST00000331769.2
ENST00000394148.3
ENST00000577675.1
colony stimulating factor 3 (granulocyte)
chr5_+_159895275 0.77 ENST00000517927.1
microRNA 146a
chr17_+_38171614 0.74 ENST00000583218.1
ENST00000394149.3
colony stimulating factor 3 (granulocyte)
chr19_-_44123734 0.73 ENST00000598676.1
zinc finger protein 428
chr14_-_106692191 0.70 ENST00000390607.2
immunoglobulin heavy variable 3-21
chr1_+_228645796 0.67 ENST00000369160.2
histone cluster 3, H2bb
chr16_-_30107491 0.64 ENST00000566134.1
ENST00000565110.1
ENST00000398841.1
ENST00000398838.4
yippee-like 3 (Drosophila)
chr19_+_39903185 0.64 ENST00000409794.3
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr20_+_33292068 0.57 ENST00000374810.3
ENST00000374809.2
ENST00000451665.1
tumor protein p53 inducible nuclear protein 2
chr19_+_42788172 0.56 ENST00000160740.3
capicua transcriptional repressor
chr1_+_149822620 0.56 ENST00000369159.2
histone cluster 2, H2aa4
chr14_-_107013465 0.55 ENST00000390625.2
immunoglobulin heavy variable 3-49
chr6_+_37137939 0.54 ENST00000373509.5
pim-1 oncogene
chr19_-_44124019 0.54 ENST00000300811.3
zinc finger protein 428
chr1_-_149814478 0.49 ENST00000369161.3
histone cluster 2, H2aa3
chr14_-_106552755 0.47 ENST00000390600.2
immunoglobulin heavy variable 3-9
chr1_+_32538492 0.46 ENST00000336294.5
transmembrane protein 39B
chr19_+_11466062 0.42 ENST00000251473.5
ENST00000591329.1
ENST00000586380.1
Lipid phosphate phosphatase-related protein type 2
chr6_+_27114861 0.42 ENST00000377459.1
histone cluster 1, H2ah
chr4_+_124320665 0.42 ENST00000394339.2
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr2_+_220143989 0.41 ENST00000336576.5
DnaJ (Hsp40) homolog, subfamily B, member 2
chr16_-_33647696 0.41 ENST00000558425.1
ENST00000569103.2
Uncharacterized protein
chr14_+_65007177 0.40 ENST00000247207.6
heat shock 70kDa protein 2
chr19_+_11466167 0.40 ENST00000591608.1
Lipid phosphate phosphatase-related protein type 2
chr16_+_33020496 0.39 ENST00000565407.2
immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr6_+_26124373 0.39 ENST00000377791.2
ENST00000602637.1
histone cluster 1, H2ac
chr2_+_220144052 0.39 ENST00000425450.1
ENST00000392086.4
ENST00000421532.1
DnaJ (Hsp40) homolog, subfamily B, member 2
chr21_+_17566643 0.38 ENST00000419952.1
ENST00000445461.2
long intergenic non-protein coding RNA 478
chr22_+_23046750 0.38 ENST00000390307.2
immunoglobulin lambda variable 3-22 (gene/pseudogene)
chr1_+_32538520 0.37 ENST00000438825.1
ENST00000456834.2
ENST00000373634.4
ENST00000427288.1
transmembrane protein 39B
chr4_-_186733363 0.37 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
sorbin and SH3 domain containing 2
chr6_-_143266297 0.36 ENST00000367603.2
human immunodeficiency virus type I enhancer binding protein 2
chr6_-_27860956 0.34 ENST00000359611.2
histone cluster 1, H2am
chr2_-_207082748 0.32 ENST00000407325.2
ENST00000411719.1
G protein-coupled receptor 1
chr1_+_61547894 0.31 ENST00000403491.3
nuclear factor I/A
chr6_+_26251835 0.30 ENST00000356350.2
histone cluster 1, H2bh
chr19_-_893200 0.30 ENST00000269814.4
ENST00000395808.3
ENST00000312090.6
ENST00000325464.1
mediator complex subunit 16
chr3_+_124303539 0.29 ENST00000428018.2
kalirin, RhoGEF kinase
chr6_-_10415218 0.29 ENST00000466073.1
ENST00000498450.1
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr18_-_61311485 0.28 ENST00000436264.1
ENST00000356424.6
ENST00000341074.5
serpin peptidase inhibitor, clade B (ovalbumin), member 4
chr14_-_106586656 0.28 ENST00000390602.2
immunoglobulin heavy variable 3-13
chr6_+_155537771 0.28 ENST00000275246.7
T-cell lymphoma invasion and metastasis 2
chr10_+_24528108 0.28 ENST00000438429.1
KIAA1217
chr8_-_33370607 0.28 ENST00000360742.5
ENST00000523305.1
TELO2 interacting protein 2
chr16_+_33629600 0.28 ENST00000562905.2
immunoglobulin heavy variable 3/OR16-13 (non-functional)
chr8_+_42396274 0.28 ENST00000438528.3
small integral membrane protein 19
chr14_+_103573853 0.27 ENST00000560304.1
exocyst complex component 3-like 4
chr9_-_140196703 0.26 ENST00000356628.2
NOTCH-regulated ankyrin repeat protein
chr11_-_3663502 0.26 ENST00000359918.4
ADP-ribosyltransferase 5
chr11_-_3663480 0.26 ENST00000397068.3
ADP-ribosyltransferase 5
chr1_+_167298281 0.26 ENST00000367862.5
POU class 2 homeobox 1
chr14_-_107199464 0.26 ENST00000433072.2
immunoglobulin heavy variable 3-72
chr19_-_18392422 0.25 ENST00000252818.3
jun D proto-oncogene
chr6_-_27100529 0.25 ENST00000607124.1
ENST00000339812.2
ENST00000541790.1
histone cluster 1, H2bj
chr10_+_106113515 0.25 ENST00000369704.3
ENST00000312902.5
coiled-coil domain containing 147
chr6_+_27782788 0.24 ENST00000359465.4
histone cluster 1, H2bm
chr12_+_122064673 0.24 ENST00000537188.1
ORAI calcium release-activated calcium modulator 1
chr7_-_50860565 0.24 ENST00000403097.1
growth factor receptor-bound protein 10
chrX_+_38660682 0.24 ENST00000457894.1
MID1 interacting protein 1
chr6_+_10585979 0.24 ENST00000265012.4
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr2_-_89266286 0.24 ENST00000464162.1
immunoglobulin kappa variable 1-6
chr19_-_45982076 0.24 ENST00000423698.2
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr2_+_89952792 0.24 ENST00000390265.2
immunoglobulin kappa variable 1D-33
chr17_+_62461569 0.24 ENST00000603557.1
ENST00000605096.1
mast cell immunoglobulin-like receptor 1
chr3_-_126327398 0.24 ENST00000383572.2
thioredoxin reductase 3 neighbor
chrX_+_38660704 0.23 ENST00000378474.3
MID1 interacting protein 1
chr19_+_41305085 0.23 ENST00000303961.4
egl-9 family hypoxia-inducible factor 2
chr18_-_53089723 0.23 ENST00000561992.1
ENST00000562512.2
transcription factor 4
chr19_+_17337027 0.23 ENST00000601529.1
ENST00000600232.1
occludin/ELL domain containing 1
chr5_-_141030943 0.23 ENST00000522783.1
ENST00000519800.1
ENST00000435817.2
FCH and double SH3 domains 1
chr22_-_27456361 0.23 ENST00000453934.1
CTA-992D9.6
chr2_-_89568263 0.23 ENST00000473726.1
immunoglobulin kappa variable 1-33
chr1_+_225600404 0.22 ENST00000366845.2
AC092811.1
chr21_+_17961006 0.22 ENST00000602323.1
long intergenic non-protein coding RNA 478
chr17_-_2966901 0.22 ENST00000575751.1
olfactory receptor, family 1, subfamily D, member 5
chr21_+_10862622 0.22 ENST00000302092.5
ENST00000559480.1
immunoglobulin heavy variable 1/OR21-1 (non-functional)
chr17_-_19651668 0.22 ENST00000494157.2
ENST00000225740.6
aldehyde dehydrogenase 3 family, member A1
chr21_-_35899113 0.22 ENST00000492600.1
ENST00000481448.1
ENST00000381132.2
regulator of calcineurin 1
chr11_-_62369291 0.22 ENST00000278823.2
metastasis associated 1 family, member 2
chr18_-_52989217 0.21 ENST00000570287.2
transcription factor 4
chr9_+_92219919 0.21 ENST00000252506.6
ENST00000375769.1
growth arrest and DNA-damage-inducible, gamma
chrX_-_107975917 0.21 ENST00000563887.1
Uncharacterized protein
chr16_+_3019552 0.21 ENST00000572687.1
progestin and adipoQ receptor family member IV
chr19_-_17516449 0.21 ENST00000252593.6
bone marrow stromal cell antigen 2
chr20_-_60982330 0.21 ENST00000279101.5
Cdk5 and Abl enzyme substrate 2
chr19_-_1132207 0.21 ENST00000438103.2
strawberry notch homolog 2 (Drosophila)
chr2_+_90458201 0.21 ENST00000603238.1
Uncharacterized protein
chrX_-_43832711 0.21 ENST00000378062.5
Norrie disease (pseudoglioma)
chr12_-_7245125 0.21 ENST00000542285.1
ENST00000540610.1
complement component 1, r subcomponent
chr15_+_67841330 0.21 ENST00000354498.5
mitogen-activated protein kinase kinase 5
chr19_-_40931891 0.20 ENST00000357949.4
SERTA domain containing 1
chr6_-_26124138 0.20 ENST00000314332.5
ENST00000396984.1
histone cluster 1, H2bc
chr12_-_11175219 0.20 ENST00000390673.2
taste receptor, type 2, member 19
chr19_-_46088068 0.20 ENST00000263275.4
ENST00000323060.3
optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr2_-_145278475 0.20 ENST00000558170.2
zinc finger E-box binding homeobox 2
chr6_-_33679452 0.20 ENST00000374231.4
ENST00000607484.1
ENST00000374214.3
ubiquinol-cytochrome c reductase complex assembly factor 2
chr14_-_68283291 0.19 ENST00000555452.1
ENST00000347230.4
zinc finger, FYVE domain containing 26
chr2_+_90211643 0.19 ENST00000390277.2
immunoglobulin kappa variable 3D-11
chr16_+_3019246 0.18 ENST00000318782.8
ENST00000293978.8
progestin and adipoQ receptor family member IV
chr12_+_107712173 0.18 ENST00000280758.5
ENST00000420571.2
BTB (POZ) domain containing 11
chr2_+_174219548 0.18 ENST00000347703.3
ENST00000392567.2
ENST00000306721.3
ENST00000410101.3
ENST00000410019.3
cell division cycle associated 7
chr19_+_17337007 0.18 ENST00000215061.4
occludin/ELL domain containing 1
chr17_+_72733350 0.18 ENST00000392613.5
ENST00000392612.3
ENST00000392610.1
RAB37, member RAS oncogene family
chr1_-_11024258 0.18 ENST00000418570.2
chromosome 1 open reading frame 127
chr12_-_11150474 0.17 ENST00000538986.1
taste receptor, type 2, member 20
chr17_-_19651654 0.17 ENST00000395555.3
aldehyde dehydrogenase 3 family, member A1
chr8_-_25902876 0.17 ENST00000520164.1
early B-cell factor 2
chr21_+_17443434 0.17 ENST00000400178.2
long intergenic non-protein coding RNA 478
chr14_-_106845789 0.17 ENST00000390617.2
immunoglobulin heavy variable 3-35 (non-functional)
chr16_-_73082274 0.17 ENST00000268489.5
zinc finger homeobox 3
chr17_+_43213004 0.17 ENST00000586346.1
ENST00000398322.3
ENST00000592162.1
ENST00000376955.4
ENST00000321854.8
acyl-CoA binding domain containing 4
chr2_+_90192768 0.17 ENST00000390275.2
immunoglobulin kappa variable 1D-13
chr10_-_63995871 0.17 ENST00000315289.2
rhotekin 2
chr2_-_89619904 0.16 ENST00000498574.1
immunoglobulin kappa variable 1-39 (gene/pseudogene)
chr14_-_106622419 0.16 ENST00000390604.2
immunoglobulin heavy variable 3-16 (non-functional)
chr3_-_112360116 0.16 ENST00000206423.3
ENST00000439685.2
coiled-coil domain containing 80
chr19_+_17337406 0.16 ENST00000597836.1
occludin/ELL domain containing 1
chr11_+_27076764 0.16 ENST00000525090.1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr15_-_89456630 0.16 ENST00000268150.8
milk fat globule-EGF factor 8 protein
chr10_-_103880209 0.16 ENST00000425280.1
LIM domain binding 1
chr11_+_64085560 0.16 ENST00000265462.4
ENST00000352435.4
ENST00000347941.4
peroxiredoxin 5
chr19_+_17337473 0.16 ENST00000598068.1
occludin/ELL domain containing 1
chr17_+_40118805 0.16 ENST00000591072.1
ENST00000587679.1
ENST00000393888.1
ENST00000441615.2
2',3'-cyclic nucleotide 3' phosphodiesterase
chr6_-_26216872 0.16 ENST00000244601.3
histone cluster 1, H2bg
chr11_+_27062860 0.15 ENST00000528583.1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr5_-_43313574 0.15 ENST00000325110.6
ENST00000433297.2
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr2_-_239148599 0.15 ENST00000409182.1
ENST00000409002.3
ENST00000450098.1
ENST00000409356.1
ENST00000409160.3
ENST00000409574.1
ENST00000272937.5
hes family bHLH transcription factor 6
chr14_-_72458326 0.15 ENST00000542853.1
AC005477.1
chr11_+_27062502 0.15 ENST00000263182.3
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr17_-_73127826 0.15 ENST00000582170.1
ENST00000245552.2
5', 3'-nucleotidase, cytosolic
chr2_-_172750733 0.15 ENST00000392592.4
ENST00000422440.2
solute carrier family 25 (aspartate/glutamate carrier), member 12
chr19_-_19281054 0.15 ENST00000424583.2
ENST00000410050.1
ENST00000409224.1
ENST00000409447.2
myocyte enhancer factor 2B
chr1_+_59775752 0.15 ENST00000371212.1
FGGY carbohydrate kinase domain containing
chr10_-_98031310 0.15 ENST00000427367.2
ENST00000413476.2
B-cell linker
chr22_+_23161491 0.15 ENST00000390316.2
immunoglobulin lambda variable 3-9 (gene/pseudogene)
chr11_-_18258342 0.14 ENST00000278222.4
serum amyloid A4, constitutive
chr7_-_130080977 0.14 ENST00000223208.5
centrosomal protein 41kDa
chr6_-_138820624 0.14 ENST00000343505.5
NHS-like 1
chr1_+_149858461 0.14 ENST00000331380.2
histone cluster 2, H2ac
chr2_-_89327228 0.14 ENST00000483158.1
immunoglobulin kappa variable 3-11
chr8_+_26435359 0.14 ENST00000311151.5
dihydropyrimidinase-like 2
chr22_+_22385332 0.14 ENST00000390282.2
immunoglobulin lambda variable 4-69
chr1_-_94586651 0.13 ENST00000535735.1
ENST00000370225.3
ATP-binding cassette, sub-family A (ABC1), member 4
chr18_-_74839891 0.13 ENST00000581878.1
myelin basic protein
chr12_+_19358228 0.13 ENST00000424268.1
ENST00000543806.1
pleckstrin homology domain containing, family A member 5
chr11_+_27062272 0.13 ENST00000529202.1
ENST00000533566.1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr2_+_90273679 0.13 ENST00000423080.2
immunoglobulin kappa variable 3D-7
chr2_-_89545079 0.13 ENST00000468494.1
immunoglobulin kappa variable 2-30
chr14_+_22293618 0.13 ENST00000390432.2
T cell receptor alpha variable 10
chr6_-_52668605 0.13 ENST00000334575.5
glutathione S-transferase alpha 1
chr2_+_145780725 0.13 ENST00000451478.1
testis expressed 41 (non-protein coding)
chr8_-_10512569 0.13 ENST00000382483.3
retinitis pigmentosa 1-like 1
chr14_-_34420259 0.13 ENST00000250457.3
ENST00000547327.2
egl-9 family hypoxia-inducible factor 3
chr2_+_97426631 0.13 ENST00000377075.2
cyclin M4
chr21_+_17442799 0.13 ENST00000602580.1
ENST00000458468.1
ENST00000602935.1
long intergenic non-protein coding RNA 478
chr6_+_116691001 0.13 ENST00000537543.1
dermatan sulfate epimerase
chr1_-_2458026 0.13 ENST00000435556.3
ENST00000378466.3
pantothenate kinase 4
chr17_-_10707410 0.13 ENST00000581851.1
long intergenic non-protein coding RNA 675
chr13_-_53422640 0.12 ENST00000338862.4
ENST00000377942.3
protocadherin 8
chr2_+_89923550 0.12 ENST00000509129.1
immunoglobulin kappa variable 1D-37 (non-functional)
chr15_-_20193370 0.12 ENST00000558565.2
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr5_-_178017355 0.12 ENST00000390654.3
collagen, type XXIII, alpha 1
chr18_-_52989525 0.12 ENST00000457482.3
transcription factor 4
chr20_+_816695 0.12 ENST00000246100.3
family with sequence similarity 110, member A
chr15_-_89456593 0.12 ENST00000558029.1
ENST00000539437.1
ENST00000542878.1
ENST00000268151.7
ENST00000566497.1
milk fat globule-EGF factor 8 protein
chr10_-_129691195 0.12 ENST00000368671.3
clarin 3
chr19_-_19144243 0.12 ENST00000594445.1
ENST00000452918.2
ENST00000600377.1
ENST00000337018.6
SURP and G patch domain containing 2
chr7_-_102789629 0.12 ENST00000417955.1
ENST00000341533.4
ENST00000425379.1
N-acyl phosphatidylethanolamine phospholipase D
chr4_-_47983519 0.12 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
cyclic nucleotide gated channel alpha 1
chr19_-_40791302 0.12 ENST00000392038.2
ENST00000578123.1
v-akt murine thymoma viral oncogene homolog 2
chr20_+_34556488 0.12 ENST00000373973.3
ENST00000349339.1
ENST00000538900.1
cyclic nucleotide binding domain containing 2
chr15_-_20170354 0.11 ENST00000338912.5
immunoglobulin heavy variable 1/OR15-9 (non-functional)
chrX_-_55020511 0.11 ENST00000375006.3
ENST00000374992.2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr19_-_47164386 0.11 ENST00000391916.2
ENST00000410105.2
dishevelled-binding antagonist of beta-catenin 3
chr5_-_66492562 0.11 ENST00000256447.4
CD180 molecule
chr19_-_50168962 0.11 ENST00000599223.1
ENST00000593922.1
ENST00000600022.1
ENST00000596765.1
ENST00000599144.1
ENST00000596822.1
ENST00000598108.1
ENST00000601373.1
ENST00000595034.1
ENST00000601291.1
interferon regulatory factor 3
chr6_-_55739542 0.11 ENST00000446683.2
bone morphogenetic protein 5
chr17_+_20059358 0.11 ENST00000536879.1
ENST00000395522.2
ENST00000395525.3
sperm antigen with calponin homology and coiled-coil domains 1
chr8_-_25315905 0.11 ENST00000221200.4
potassium channel tetramerization domain containing 9
chr6_+_27215471 0.11 ENST00000421826.2
protease, serine, 16 (thymus)
chr14_-_106573756 0.11 ENST00000390601.2
immunoglobulin heavy variable 3-11 (gene/pseudogene)
chr19_+_1269324 0.11 ENST00000589710.1
ENST00000588230.1
ENST00000413636.2
ENST00000586472.1
ENST00000589686.1
ENST00000444172.2
ENST00000587323.1
ENST00000320936.5
ENST00000587896.1
ENST00000589235.1
ENST00000591659.1
cold inducible RNA binding protein
chr20_+_32150140 0.11 ENST00000344201.3
ENST00000346541.3
ENST00000397800.1
ENST00000397798.2
ENST00000492345.1
core-binding factor, runt domain, alpha subunit 2; translocated to, 2
chrX_+_134654540 0.11 ENST00000370752.4
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr4_-_163085141 0.11 ENST00000427802.2
ENST00000306100.5
follistatin-like 5
chr2_+_89901292 0.11 ENST00000448155.2
immunoglobulin kappa variable 1D-39
chr19_-_8373173 0.11 ENST00000537716.2
ENST00000301458.5
CD320 molecule
chr12_+_14927270 0.11 ENST00000544848.1
H2A histone family, member J
chr2_-_158182410 0.11 ENST00000419116.2
ENST00000410096.1
ermin, ERM-like protein
chr6_+_27215494 0.10 ENST00000230582.3
protease, serine, 16 (thymus)
chr20_-_49547731 0.10 ENST00000396029.3
activity-dependent neuroprotector homeobox
chr4_-_163085107 0.10 ENST00000379164.4
follistatin-like 5
chr15_+_67458357 0.10 ENST00000537194.2
SMAD family member 3
chr17_-_37382105 0.10 ENST00000333461.5
SH3 and cysteine rich domain 2
chr16_-_21314360 0.10 ENST00000219599.3
ENST00000576703.1
crystallin, mu
chr21_+_17443521 0.10 ENST00000456342.1
long intergenic non-protein coding RNA 478

Network of associatons between targets according to the STRING database.

First level regulatory network of POU2F2_POU3F1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0003409 optic cup structural organization(GO:0003409)
0.2 0.8 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.1 0.4 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.1 1.5 GO:0030223 neutrophil differentiation(GO:0030223)
0.1 0.1 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.1 0.3 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1 0.1 GO:0055096 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.1 0.2 GO:0002731 negative regulation of dendritic cell cytokine production(GO:0002731) negative regulation of intracellular transport of viral material(GO:1901253)
0.1 0.6 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.1 0.6 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.2 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.2 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.3 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.0 0.2 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.2 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) post-embryonic hemopoiesis(GO:0035166)
0.0 0.2 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.2 GO:0071105 response to interleukin-11(GO:0071105)
0.0 0.1 GO:0030451 regulation of complement activation, alternative pathway(GO:0030451) negative regulation of complement activation, alternative pathway(GO:0045957)
0.0 0.2 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.2 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.2 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.1 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.0 0.1 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.0 0.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.3 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.1 GO:0009644 response to high light intensity(GO:0009644) cellular response to light intensity(GO:0071484)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 1.9 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:0031296 B cell costimulation(GO:0031296)
0.0 0.3 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.2 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.5 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.1 GO:0061183 dermatome development(GO:0061054) regulation of dermatome development(GO:0061183) regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.0 0.1 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.0 0.1 GO:0060018 astrocyte fate commitment(GO:0060018)
0.0 0.5 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.2 GO:0035900 response to isolation stress(GO:0035900) regulation of eating behavior(GO:1903998)
0.0 0.2 GO:0035290 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.0 0.1 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.1 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.2 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.4 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.4 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.1 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.1 GO:0014016 neuroblast differentiation(GO:0014016)
0.0 0.3 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.3 GO:0071888 macrophage apoptotic process(GO:0071888)
0.0 0.1 GO:0048867 ganglion mother cell fate determination(GO:0007402) stem cell fate determination(GO:0048867)
0.0 0.1 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.0 0.2 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.0 0.1 GO:0060031 mediolateral intercalation(GO:0060031) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775)
0.0 0.1 GO:1903803 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.0 0.1 GO:0061290 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.0 0.2 GO:0046325 negative regulation of glucose import(GO:0046325)
0.0 0.3 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0021540 corpus callosum morphogenesis(GO:0021540)
0.0 0.0 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.0 0.1 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.1 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 1.6 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.0 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.5 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.0 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0 0.1 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.0 GO:0003099 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0 0.4 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.0 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.0 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0 0.1 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.0 0.3 GO:0009223 pyrimidine deoxyribonucleotide catabolic process(GO:0009223) pyrimidine nucleoside catabolic process(GO:0046135)
0.0 0.1 GO:0030047 actin modification(GO:0030047)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.2 GO:0009642 response to light intensity(GO:0009642)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0036128 CatSper complex(GO:0036128)
0.0 3.1 GO:0000786 nucleosome(GO:0000786)
0.0 1.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.3 GO:0035976 AP1 complex(GO:0035976)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.5 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.1 0.3 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.2 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.6 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.1 GO:0015235 cobalamin transporter activity(GO:0015235)
0.0 0.1 GO:0004877 complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
0.0 0.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.2 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.3 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 1.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.5 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.2 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.3 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.0 0.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.1 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.8 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0008379 RNA polymerase III regulatory region DNA binding(GO:0001016) thioredoxin peroxidase activity(GO:0008379)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.0 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0016160 amylase activity(GO:0016160)
0.0 0.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.3 GO:0042923 neuropeptide binding(GO:0042923)
0.0 1.4 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.0 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.1 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.0 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.2 GO:0045499 chemorepellent activity(GO:0045499)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID IL5 PATHWAY IL5-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.3 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 1.2 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.3 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network