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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for POU3F2

Z-value: 1.13

Motif logo

Transcription factors associated with POU3F2

Gene Symbol Gene ID Gene Info
ENSG00000184486.7 POU class 3 homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU3F2hg19_v2_chr6_+_99282570_99282591-0.135.4e-01Click!

Activity profile of POU3F2 motif

Sorted Z-values of POU3F2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_76957214 5.90 ENST00000306621.3
chemokine (C-X-C motif) ligand 11
chr3_-_127455200 5.22 ENST00000398101.3
monoglyceride lipase
chr2_+_152214098 4.15 ENST00000243347.3
tumor necrosis factor, alpha-induced protein 6
chr11_+_5710919 3.20 ENST00000379965.3
ENST00000425490.1
tripartite motif containing 22
chr10_+_91087651 3.01 ENST00000371818.4
interferon-induced protein with tetratricopeptide repeats 3
chr11_-_102668879 2.92 ENST00000315274.6
matrix metallopeptidase 1 (interstitial collagenase)
chr1_-_173020056 2.87 ENST00000239468.2
ENST00000404377.3
tumor necrosis factor (ligand) superfamily, member 18
chr10_-_49860525 2.85 ENST00000435790.2
Rho GTPase activating protein 22
chr4_-_76944621 2.81 ENST00000306602.1
chemokine (C-X-C motif) ligand 10
chr11_+_20044600 2.77 ENST00000311043.8
neuron navigator 2
chr17_-_34207295 2.47 ENST00000463941.1
ENST00000293272.3
chemokine (C-C motif) ligand 5
chr12_+_117348742 2.37 ENST00000309909.5
ENST00000455858.2
F-box and WD repeat domain containing 8
chr3_-_122283079 2.31 ENST00000471785.1
ENST00000466126.1
poly (ADP-ribose) polymerase family, member 9
chr3_+_173116225 2.06 ENST00000457714.1
neuroligin 1
chr4_+_74702214 1.98 ENST00000226317.5
ENST00000515050.1
chemokine (C-X-C motif) ligand 6
chr10_+_91152303 1.94 ENST00000371804.3
interferon-induced protein with tetratricopeptide repeats 1
chr2_-_225811747 1.94 ENST00000409592.3
dedicator of cytokinesis 10
chr20_-_35580240 1.90 ENST00000262878.4
SAM domain and HD domain 1
chr1_+_169079823 1.86 ENST00000367813.3
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr2_-_216878305 1.79 ENST00000263268.6
melanoregulin
chr1_-_89488510 1.77 ENST00000564665.1
ENST00000370481.4
guanylate binding protein 3
chr4_+_89299885 1.72 ENST00000380265.5
ENST00000273960.3
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr11_+_20044096 1.69 ENST00000533917.1
neuron navigator 2
chr3_+_122283064 1.67 ENST00000296161.4
deltex 3-like (Drosophila)
chr3_-_123339343 1.65 ENST00000578202.1
myosin light chain kinase
chr1_+_79086088 1.65 ENST00000370751.5
ENST00000342282.3
interferon-induced protein 44-like
chr1_-_8000872 1.64 ENST00000377507.3
tumor necrosis factor receptor superfamily, member 9
chr6_+_132891461 1.61 ENST00000275198.1
trace amine associated receptor 6
chr6_+_127898312 1.60 ENST00000329722.7
chromosome 6 open reading frame 58
chr21_+_43619796 1.54 ENST00000398457.2
ATP-binding cassette, sub-family G (WHITE), member 1
chr15_+_67418047 1.53 ENST00000540846.2
SMAD family member 3
chr16_+_57023406 1.51 ENST00000262510.6
ENST00000308149.7
ENST00000436936.1
NLR family, CARD domain containing 5
chr3_-_79068594 1.51 ENST00000436010.2
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr4_+_89299994 1.49 ENST00000264346.7
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chrX_+_30261847 1.45 ENST00000378981.3
ENST00000397550.1
melanoma antigen family B, 1
chr2_+_127413481 1.43 ENST00000259254.4
glycophorin C (Gerbich blood group)
chr3_-_123339418 1.42 ENST00000583087.1
myosin light chain kinase
chr8_-_6836156 1.39 ENST00000382679.2
defensin, alpha 1
chr18_+_61554932 1.38 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr2_+_102928009 1.34 ENST00000404917.2
ENST00000447231.1
interleukin 1 receptor-like 1
chr8_-_90996837 1.32 ENST00000519426.1
ENST00000265433.3
nibrin
chr8_+_132952112 1.28 ENST00000520362.1
ENST00000519656.1
EFR3 homolog A (S. cerevisiae)
chr19_-_53466095 1.28 ENST00000391786.2
ENST00000434371.2
ENST00000357666.4
ENST00000438970.2
ENST00000270457.4
ENST00000535506.1
ENST00000444460.2
ENST00000457013.2
zinc finger protein 816
chr7_-_92777606 1.27 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
sterile alpha motif domain containing 9-like
chr1_-_156571254 1.26 ENST00000438976.2
ENST00000334588.7
ENST00000368232.4
ENST00000415314.2
G patch domain containing 4
chr5_-_13944652 1.26 ENST00000265104.4
dynein, axonemal, heavy chain 5
chr5_+_35856951 1.25 ENST00000303115.3
ENST00000343305.4
ENST00000506850.1
ENST00000511982.1
interleukin 7 receptor
chr14_+_22538811 1.25 ENST00000390450.3
T cell receptor alpha variable 22
chr15_-_55541227 1.23 ENST00000566877.1
RAB27A, member RAS oncogene family
chr3_+_151531810 1.23 ENST00000232892.7
arylacetamide deacetylase
chr5_-_58652788 1.23 ENST00000405755.2
phosphodiesterase 4D, cAMP-specific
chr3_-_194188956 1.21 ENST00000256031.4
ENST00000446356.1
ATPase type 13A3
chr6_+_29274403 1.20 ENST00000377160.2
olfactory receptor, family 14, subfamily J, member 1
chr17_+_41158742 1.19 ENST00000415816.2
ENST00000438323.2
interferon-induced protein 35
chr1_-_173174681 1.18 ENST00000367718.1
tumor necrosis factor (ligand) superfamily, member 4
chr1_-_89736434 1.18 ENST00000370459.3
guanylate binding protein 5
chr3_-_122283100 1.16 ENST00000492382.1
ENST00000462315.1
poly (ADP-ribose) polymerase family, member 9
chr19_-_50400212 1.15 ENST00000391826.2
interleukin 4 induced 1
chr17_+_18380051 1.15 ENST00000581545.1
ENST00000582333.1
ENST00000328114.6
ENST00000412421.2
ENST00000583322.1
ENST00000584941.1
lectin, galactoside-binding, soluble, 9C
chr20_-_35580104 1.15 ENST00000373694.5
SAM domain and HD domain 1
chr7_-_55930443 1.14 ENST00000388975.3
septin 14
chr4_-_120550146 1.14 ENST00000354960.3
phosphodiesterase 5A, cGMP-specific
chr11_-_72504681 1.13 ENST00000538536.1
ENST00000543304.1
ENST00000540587.1
ENST00000334805.6
StAR-related lipid transfer (START) domain containing 10
chr21_+_27011584 1.12 ENST00000400532.1
ENST00000480456.1
ENST00000312957.5
junctional adhesion molecule 2
chr18_-_53804580 1.11 ENST00000590484.1
ENST00000589293.1
ENST00000587904.1
ENST00000591974.1
RP11-456O19.4
chr22_-_50051151 1.10 ENST00000400023.1
ENST00000444628.1
chromosome 22 open reading frame 34
chr12_-_89919765 1.08 ENST00000541909.1
ENST00000313546.3
POC1 centriolar protein B
chr7_-_47579188 1.07 ENST00000398879.1
ENST00000355730.3
ENST00000442536.2
ENST00000458317.2
tensin 3
chr12_+_9822331 1.06 ENST00000545918.1
ENST00000543300.1
ENST00000261339.6
ENST00000466035.2
C-type lectin domain family 2, member D
chr11_+_1718425 1.06 ENST00000382160.1
keratin associated protein 5-6
chr12_+_21207503 1.04 ENST00000545916.1
solute carrier organic anion transporter family, member 1B7 (non-functional)
chrX_-_68385354 1.03 ENST00000361478.1
praja ring finger 1, E3 ubiquitin protein ligase
chr4_-_169239921 1.03 ENST00000514995.1
ENST00000393743.3
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr2_-_241396131 1.03 ENST00000404327.3
Uncharacterized protein
chr6_-_82462425 1.02 ENST00000369754.3
ENST00000320172.6
ENST00000369756.3
family with sequence similarity 46, member A
chr3_-_107777208 1.02 ENST00000398258.3
CD47 molecule
chr3_-_122283424 1.00 ENST00000477522.2
ENST00000360356.2
poly (ADP-ribose) polymerase family, member 9
chr8_-_90996459 1.00 ENST00000517337.1
ENST00000409330.1
nibrin
chr15_+_71389281 0.98 ENST00000355327.3
thrombospondin, type I, domain containing 4
chr1_-_150208320 0.97 ENST00000534220.1
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr16_-_75590114 0.95 ENST00000568377.1
ENST00000565067.1
ENST00000258173.6
transmembrane protein 231
chrX_-_68385274 0.94 ENST00000374584.3
ENST00000590146.1
praja ring finger 1, E3 ubiquitin protein ligase
chr1_+_15986364 0.92 ENST00000345034.1
regulatory solute carrier protein, family 1, member 1
chr1_+_165864800 0.91 ENST00000469256.2
uridine-cytidine kinase 2
chr2_-_197226875 0.91 ENST00000409111.1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr11_+_35201826 0.91 ENST00000531873.1
CD44 molecule (Indian blood group)
chr17_+_77030267 0.91 ENST00000581774.1
C1q and tumor necrosis factor related protein 1
chr4_-_122085469 0.90 ENST00000057513.3
TNFAIP3 interacting protein 3
chr1_-_89591749 0.89 ENST00000370466.3
guanylate binding protein 2, interferon-inducible
chr2_+_231280954 0.88 ENST00000409824.1
ENST00000409341.1
ENST00000409112.1
ENST00000340126.4
ENST00000341950.4
SP100 nuclear antigen
chr7_-_32338917 0.88 ENST00000396193.1
phosphodiesterase 1C, calmodulin-dependent 70kDa
chr19_+_52839515 0.88 ENST00000403906.3
ENST00000601151.1
zinc finger protein 610
chr19_+_52839490 0.88 ENST00000321287.8
zinc finger protein 610
chr19_-_40023450 0.87 ENST00000326282.4
EP300 interacting inhibitor of differentiation 2B
chr1_+_165864821 0.86 ENST00000470820.1
uridine-cytidine kinase 2
chr22_-_36018569 0.85 ENST00000419229.1
ENST00000406324.1
myoglobin
chr8_+_104310661 0.84 ENST00000522566.1
frizzled family receptor 6
chr8_+_92082424 0.83 ENST00000285420.4
ENST00000404789.3
OTU domain containing 6B
chr5_+_156712372 0.83 ENST00000541131.1
cytoplasmic FMR1 interacting protein 2
chr3_-_157251383 0.83 ENST00000487753.1
ENST00000489602.1
ENST00000461299.1
ENST00000479987.1
ventricular zone expressed PH domain-containing 1
chr11_-_3400330 0.82 ENST00000427810.2
ENST00000005082.9
ENST00000534569.1
ENST00000438262.2
ENST00000528796.1
ENST00000528410.1
ENST00000529678.1
ENST00000354599.6
ENST00000526601.1
ENST00000525502.1
ENST00000533036.1
ENST00000399602.4
zinc finger protein 195
chr11_-_62997124 0.81 ENST00000306494.6
solute carrier family 22, member 25
chr7_-_139763521 0.81 ENST00000263549.3
poly (ADP-ribose) polymerase family, member 12
chr22_-_50050986 0.80 ENST00000405854.1
chromosome 22 open reading frame 34
chr1_-_205091115 0.80 ENST00000264515.6
ENST00000367164.1
retinoblastoma binding protein 5
chr3_+_29322803 0.80 ENST00000396583.3
ENST00000383767.2
RNA binding motif, single stranded interacting protein 3
chr3_-_169487617 0.80 ENST00000330368.2
actin-related protein T3
chr12_+_102271129 0.79 ENST00000258534.8
DNA-damage regulated autophagy modulator 1
chr6_-_128841503 0.78 ENST00000368215.3
ENST00000532331.1
ENST00000368213.5
ENST00000368207.3
ENST00000525459.1
ENST00000368210.3
ENST00000368226.4
ENST00000368227.3
protein tyrosine phosphatase, receptor type, K
chr11_+_55594695 0.77 ENST00000378397.1
olfactory receptor, family 5, subfamily L, member 2
chr5_-_150460914 0.76 ENST00000389378.2
TNFAIP3 interacting protein 1
chr4_-_120549163 0.76 ENST00000394439.1
ENST00000420633.1
phosphodiesterase 5A, cGMP-specific
chr15_-_55563072 0.76 ENST00000567380.1
ENST00000565972.1
ENST00000569493.1
RAB27A, member RAS oncogene family
chr15_+_94899183 0.75 ENST00000557742.1
multiple C2 domains, transmembrane 2
chr6_+_13182751 0.73 ENST00000415087.1
phosphatase and actin regulator 1
chr21_-_47352477 0.73 ENST00000593412.1
Uncharacterized protein
chr3_-_157221380 0.73 ENST00000468233.1
ventricular zone expressed PH domain-containing 1
chr17_+_25958174 0.72 ENST00000313648.6
ENST00000577392.1
ENST00000584661.1
ENST00000413914.2
lectin, galactoside-binding, soluble, 9
chrX_+_11129388 0.72 ENST00000321143.4
ENST00000380763.3
ENST00000380762.4
holocytochrome c synthase
chr9_-_97090926 0.72 ENST00000335456.7
ENST00000253262.4
ENST00000341207.4
NUT family member 2F
chr21_+_43919710 0.71 ENST00000398341.3
solute carrier family 37 (glucose-6-phosphate transporter), member 1
chr19_-_47291843 0.71 ENST00000542575.2
solute carrier family 1 (neutral amino acid transporter), member 5
chr3_+_130569429 0.71 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATPase, Ca++ transporting, type 2C, member 1
chr19_-_44174330 0.70 ENST00000340093.3
plasminogen activator, urokinase receptor
chr14_+_52164820 0.70 ENST00000554167.1
FERM domain containing 6
chr3_-_4927447 0.69 ENST00000449914.1
Uncharacterized protein
chr6_-_101329191 0.68 ENST00000324723.6
ENST00000369162.2
ENST00000522650.1
activating signal cointegrator 1 complex subunit 3
chr2_-_231090344 0.68 ENST00000540870.1
ENST00000416610.1
SP110 nuclear body protein
chr2_-_37544209 0.68 ENST00000234179.2
protein kinase D3
chr11_-_104972158 0.68 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chrX_+_144908928 0.68 ENST00000408967.2
transmembrane protein 257
chr5_+_96211643 0.68 ENST00000437043.3
ENST00000510373.1
endoplasmic reticulum aminopeptidase 2
chr15_-_56209306 0.68 ENST00000506154.1
ENST00000338963.2
ENST00000508342.1
neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
chr8_+_104892639 0.67 ENST00000436393.2
regulating synaptic membrane exocytosis 2
chr16_+_10837643 0.67 ENST00000574334.1
ENST00000283027.5
ENST00000433392.2
nucleotide binding protein 1
chr5_-_59481406 0.67 ENST00000546160.1
phosphodiesterase 4D, cAMP-specific
chr7_+_107204389 0.66 ENST00000265720.3
ENST00000402620.1
dihydrouridine synthase 4-like (S. cerevisiae)
chr6_+_149539767 0.66 ENST00000606202.1
ENST00000536230.1
ENST00000445901.1
TGF-beta activated kinase 1/MAP3K7 binding protein 2
RP1-111D6.3
chr9_-_2844058 0.66 ENST00000397885.2
KIAA0020
chr1_+_111682058 0.66 ENST00000545121.1
choline/ethanolamine phosphotransferase 1
chr17_+_56232494 0.65 ENST00000268912.5
olfactory receptor, family 4, subfamily D, member 1
chr2_+_143635067 0.65 ENST00000264170.4
kynureninase
chr21_+_35736302 0.65 ENST00000290310.3
potassium voltage-gated channel, Isk-related family, member 2
chr15_+_71185148 0.65 ENST00000443425.2
ENST00000560755.1
leucine rich repeat containing 49
chr2_-_224810070 0.64 ENST00000429915.1
ENST00000233055.4
WD repeat and FYVE domain containing 1
chr12_-_11214893 0.64 ENST00000533467.1
taste receptor, type 2, member 46
chr17_+_33570055 0.64 ENST00000299977.4
ENST00000542451.1
ENST00000592325.1
schlafen family member 5
chr19_-_44174305 0.63 ENST00000601723.1
ENST00000339082.3
plasminogen activator, urokinase receptor
chr12_-_71182695 0.63 ENST00000342084.4
protein tyrosine phosphatase, receptor type, R
chr1_+_244998918 0.63 ENST00000366528.3
COX20 cytochrome C oxidase assembly factor
chr6_-_25830785 0.62 ENST00000468082.1
solute carrier family 17 (organic anion transporter), member 1
chr3_-_151047327 0.62 ENST00000325602.5
purinergic receptor P2Y, G-protein coupled, 13
chr12_-_89920030 0.62 ENST00000413530.1
ENST00000547474.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
POC1B-GALNT4 readthrough
chr20_+_816695 0.62 ENST00000246100.3
family with sequence similarity 110, member A
chr6_+_42847649 0.61 ENST00000424341.2
ENST00000602561.1
ribosomal protein L7-like 1
chr2_+_68872954 0.61 ENST00000394342.2
prokineticin receptor 1
chr18_+_76829441 0.61 ENST00000458297.2
ATPase, class II, type 9B
chr8_+_104426942 0.61 ENST00000297579.5
DDB1 and CUL4 associated factor 13
chr12_-_89919965 0.61 ENST00000548729.1
POC1B-GALNT4 readthrough
chr22_-_17680472 0.61 ENST00000330232.4
cat eye syndrome chromosome region, candidate 1
chr11_-_11747257 0.60 ENST00000601641.1
AC131935.1
chr6_+_53948328 0.60 ENST00000370876.2
muscular LMNA-interacting protein
chr2_-_113542063 0.60 ENST00000263339.3
interleukin 1, alpha
chr2_-_70475586 0.60 ENST00000416149.2
TIA1 cytotoxic granule-associated RNA binding protein
chr10_-_14050522 0.60 ENST00000342409.2
FERM domain containing 4A
chr1_+_152635854 0.59 ENST00000368784.1
late cornified envelope 2D
chr20_+_44746939 0.59 ENST00000372276.3
CD40 molecule, TNF receptor superfamily member 5
chr3_+_88198838 0.58 ENST00000318887.3
chromosome 3 open reading frame 38
chr11_-_104827425 0.58 ENST00000393150.3
caspase 4, apoptosis-related cysteine peptidase
chr2_-_231989808 0.58 ENST00000258400.3
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr3_-_157221357 0.58 ENST00000494677.1
ventricular zone expressed PH domain-containing 1
chr2_+_162016827 0.57 ENST00000429217.1
ENST00000406287.1
ENST00000402568.1
TRAF family member-associated NFKB activator
chr15_-_55562479 0.57 ENST00000564609.1
RAB27A, member RAS oncogene family
chr12_+_15125954 0.57 ENST00000266395.2
phosphodiesterase 6H, cGMP-specific, cone, gamma
chr4_+_103422471 0.57 ENST00000226574.4
ENST00000394820.4
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr11_+_61957687 0.57 ENST00000306238.3
secretoglobin, family 1D, member 1
chr1_+_172389821 0.57 ENST00000367727.4
chromosome 1 open reading frame 105
chr2_+_152266604 0.57 ENST00000430328.2
RAP1 interacting factor homolog (yeast)
chr2_+_102721023 0.56 ENST00000409589.1
ENST00000409329.1
interleukin 1 receptor, type I
chr3_+_130650738 0.56 ENST00000504612.1
ATPase, Ca++ transporting, type 2C, member 1
chr2_+_161993465 0.56 ENST00000457476.1
TRAF family member-associated NFKB activator
chr11_-_75017734 0.56 ENST00000532525.1
arrestin, beta 1
chr3_-_112564797 0.56 ENST00000398214.1
ENST00000448932.1
CD200 receptor 1-like
chr7_+_107531580 0.56 ENST00000537148.1
ENST00000440410.1
ENST00000437604.2
dihydrolipoamide dehydrogenase
chrX_-_27417088 0.55 ENST00000608735.1
ENST00000422048.1
RP11-268G12.1
chr12_+_12764773 0.55 ENST00000228865.2
cAMP responsive element binding protein-like 2
chr12_+_72058130 0.55 ENST00000547843.1
THAP domain containing, apoptosis associated protein 2
chr16_+_56659687 0.55 ENST00000568293.1
ENST00000330439.6
metallothionein 1E
chr2_+_231280908 0.55 ENST00000427101.2
ENST00000432979.1
SP100 nuclear antigen
chr17_+_53828333 0.55 ENST00000268896.5
phosphatidylcholine transfer protein
chr15_-_89764929 0.55 ENST00000268125.5
retinaldehyde binding protein 1
chrX_+_36254051 0.55 ENST00000378657.4
chromosome X open reading frame 30
chr2_-_152146385 0.54 ENST00000414946.1
ENST00000243346.5
N-myc (and STAT) interactor
chr13_+_48611665 0.54 ENST00000258662.2
nudix (nucleoside diphosphate linked moiety X)-type motif 15
chr1_+_244816371 0.53 ENST00000263831.7
desumoylating isopeptidase 2
chr18_+_61575200 0.53 ENST00000238508.3
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr1_-_144994840 0.53 ENST00000369351.3
ENST00000369349.3
phosphodiesterase 4D interacting protein
chr5_+_76114758 0.53 ENST00000514165.1
ENST00000296677.4
coagulation factor II (thrombin) receptor-like 1
chr12_+_93096619 0.52 ENST00000397833.3
chromosome 12 open reading frame 74
chr4_+_128702969 0.52 ENST00000508776.1
ENST00000439123.2
heat shock 70kDa protein 4-like

Network of associatons between targets according to the STRING database.

First level regulatory network of POU3F2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 8.7 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.7 5.2 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.7 2.9 GO:2000329 negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.7 3.6 GO:0006203 dGTP catabolic process(GO:0006203)
0.7 2.1 GO:0099545 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.6 1.9 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.6 2.5 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.6 2.5 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.6 4.5 GO:0021564 vagus nerve development(GO:0021564)
0.5 3.1 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.5 1.5 GO:0021836 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.5 1.4 GO:0035915 pore formation in membrane of other organism(GO:0035915)
0.5 4.6 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.5 1.4 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.4 1.8 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.4 1.2 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.4 1.5 GO:0009726 detection of endogenous stimulus(GO:0009726)
0.4 2.3 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.4 1.9 GO:1903288 positive regulation of calcium:sodium antiporter activity(GO:1903281) positive regulation of potassium ion import(GO:1903288)
0.4 1.4 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.3 1.3 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.3 1.5 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.3 2.6 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.3 1.7 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.3 1.7 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.3 1.6 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.3 1.9 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.3 1.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.3 1.0 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.3 2.3 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.3 1.3 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.2 3.2 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.2 0.9 GO:1902159 regulation of cyclic nucleotide-gated ion channel activity(GO:1902159)
0.2 0.6 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.2 0.8 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.2 0.2 GO:0031990 mRNA export from nucleus in response to heat stress(GO:0031990)
0.2 0.8 GO:0009106 lipoate metabolic process(GO:0009106)
0.2 0.6 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.2 1.2 GO:2000391 positive regulation of neutrophil extravasation(GO:2000391)
0.2 0.8 GO:0085032 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.2 0.6 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.2 0.9 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.2 0.7 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.2 0.5 GO:1903572 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.2 1.1 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.2 0.7 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.2 0.7 GO:1903803 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.2 1.1 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.2 0.5 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.2 0.7 GO:0089700 protein kinase D signaling(GO:0089700)
0.2 0.7 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.2 0.5 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.2 0.3 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
0.2 0.6 GO:0042231 interleukin-13 biosynthetic process(GO:0042231)
0.2 0.5 GO:1990569 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.2 2.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.2 0.6 GO:0003095 pressure natriuresis(GO:0003095)
0.2 1.1 GO:0033590 response to cobalamin(GO:0033590)
0.1 1.2 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1 3.0 GO:0021670 lateral ventricle development(GO:0021670)
0.1 0.7 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 4.4 GO:0030728 ovulation(GO:0030728)
0.1 0.6 GO:0097325 melanocyte proliferation(GO:0097325)
0.1 1.7 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.4 GO:2000317 negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.1 1.2 GO:0032621 interleukin-18 production(GO:0032621)
0.1 0.8 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.1 0.3 GO:0032730 positive regulation of interleukin-1 alpha production(GO:0032730)
0.1 1.3 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.1 0.5 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.1 1.5 GO:0032782 bile acid secretion(GO:0032782)
0.1 0.5 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1 0.4 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.1 0.9 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 0.3 GO:1900073 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
0.1 0.3 GO:0071030 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.1 0.9 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 0.6 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) positive regulation of miRNA metabolic process(GO:2000630)
0.1 0.9 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 0.3 GO:0061713 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.1 0.3 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1 0.3 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.1 0.4 GO:0031049 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) regulation of cellular response to X-ray(GO:2000683) positive regulation of cellular response to X-ray(GO:2000685)
0.1 0.3 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.1 0.7 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.1 0.8 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.1 0.2 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.1 0.4 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.1 2.6 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.1 0.7 GO:0003383 apical constriction(GO:0003383)
0.1 0.3 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.1 0.4 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.1 1.2 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.1 0.3 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.2 GO:0045404 positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.1 0.6 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.1 0.4 GO:0019605 butyrate metabolic process(GO:0019605)
0.1 0.4 GO:0035425 autocrine signaling(GO:0035425)
0.1 0.4 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.1 1.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 0.3 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.1 0.6 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.1 0.4 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 0.7 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.1 0.4 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.3 GO:0001794 type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) positive regulation of type IIa hypersensitivity(GO:0001798) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892) positive regulation of type II hypersensitivity(GO:0002894)
0.1 0.3 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.1 0.8 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1 0.3 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 0.9 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.2 GO:0002254 kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.1 2.6 GO:0042730 fibrinolysis(GO:0042730)
0.1 0.3 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.7 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.1 0.2 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.1 0.2 GO:1903487 regulation of lactation(GO:1903487)
0.1 0.3 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.1 0.5 GO:0001880 Mullerian duct regression(GO:0001880)
0.1 0.5 GO:0090131 mesenchyme migration(GO:0090131)
0.1 0.3 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 1.0 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.1 1.1 GO:0015747 urate transport(GO:0015747)
0.1 2.9 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.1 0.5 GO:0010265 SCF complex assembly(GO:0010265)
0.1 0.2 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.1 0.4 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.1 0.4 GO:0022614 membrane to membrane docking(GO:0022614)
0.1 0.2 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.1 0.2 GO:0044278 cell wall disruption in other organism(GO:0044278)
0.1 0.1 GO:0045626 negative regulation of T-helper 1 cell differentiation(GO:0045626)
0.1 0.2 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.1 0.2 GO:0090149 synaptic vesicle recycling via endosome(GO:0036466) mitochondrial membrane fission(GO:0090149) positive regulation of synaptic vesicle endocytosis(GO:1900244) positive regulation of synaptic vesicle recycling(GO:1903423) positive regulation of synaptic vesicle exocytosis(GO:2000302)
0.1 0.2 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.1 0.3 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.1 1.5 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.9 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.4 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 0.4 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.1 0.3 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.1 0.3 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 0.5 GO:0035624 receptor transactivation(GO:0035624)
0.1 0.5 GO:0070778 L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712)
0.1 0.3 GO:0051461 positive regulation of corticotropin secretion(GO:0051461)
0.1 0.2 GO:0006624 vacuolar protein processing(GO:0006624)
0.1 0.2 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.1 0.5 GO:0051182 coenzyme transport(GO:0051182)
0.1 0.3 GO:0007343 egg activation(GO:0007343)
0.1 0.2 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.1 0.2 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 0.2 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.4 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 0.2 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.1 0.3 GO:1902573 positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
0.1 0.1 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
0.1 0.2 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 0.5 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 0.3 GO:0046502 uroporphyrinogen III biosynthetic process(GO:0006780) uroporphyrinogen III metabolic process(GO:0046502)
0.1 0.2 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.1 0.2 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
0.1 0.2 GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841) positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.1 0.1 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.1 0.6 GO:0050957 equilibrioception(GO:0050957)
0.1 0.2 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.1 0.6 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.1 0.2 GO:0001983 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.1 0.7 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 0.2 GO:0097052 L-kynurenine metabolic process(GO:0097052)
0.1 0.2 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 0.3 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.1 0.4 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 0.3 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484) negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.1 0.5 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.6 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.1 0.2 GO:0006408 snRNA export from nucleus(GO:0006408)
0.1 0.2 GO:0019860 transformation of host cell by virus(GO:0019087) uracil metabolic process(GO:0019860)
0.1 0.5 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205)
0.1 0.7 GO:0019532 oxalate transport(GO:0019532)
0.0 0.7 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.4 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.3 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.3 GO:0010896 regulation of triglyceride catabolic process(GO:0010896)
0.0 0.7 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.1 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.0 0.7 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.1 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.0 0.4 GO:0021943 formation of radial glial scaffolds(GO:0021943)
0.0 0.2 GO:0060356 leucine import(GO:0060356)
0.0 0.3 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.0 0.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.6 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.1 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.0 0.2 GO:0048749 compound eye development(GO:0048749)
0.0 0.1 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.0 0.2 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.3 GO:0070944 neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) neutrophil mediated killing of bacterium(GO:0070944)
0.0 0.2 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.0 0.9 GO:0008228 opsonization(GO:0008228)
0.0 0.5 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.1 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0 0.1 GO:1901536 negative regulation of DNA demethylation(GO:1901536)
0.0 0.2 GO:0000023 maltose metabolic process(GO:0000023)
0.0 0.4 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.5 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.2 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 1.0 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.8 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.2 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0 0.3 GO:1902510 regulation of apoptotic DNA fragmentation(GO:1902510)
0.0 0.3 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.3 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.5 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.2 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.3 GO:0033504 floor plate development(GO:0033504)
0.0 2.8 GO:0070206 protein trimerization(GO:0070206)
0.0 0.7 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.2 GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.0 0.1 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
0.0 0.3 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.2 GO:1990523 response to vitamin K(GO:0032571) bone regeneration(GO:1990523)
0.0 0.2 GO:0043323 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.0 0.2 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.5 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.1 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.0 0.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.6 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.3 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.1 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.0 0.3 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.1 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0 0.2 GO:0097694 establishment of RNA localization to telomere(GO:0097694) establishment of macromolecular complex localization to telomere(GO:0097695)
0.0 0.5 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.7 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.0 0.3 GO:0045915 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0043126 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.0 0.5 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.6 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.2 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.4 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.3 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.2 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.1 GO:0001694 histamine biosynthetic process(GO:0001694)
0.0 0.1 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.5 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 1.5 GO:0009452 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
0.0 0.2 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.2 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.1 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.0 0.2 GO:1904798 positive regulation of core promoter binding(GO:1904798)
0.0 3.3 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.4 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.2 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.3 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.2 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.1 GO:0032053 ciliary basal body organization(GO:0032053)
0.0 0.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.4 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.3 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112)
0.0 0.4 GO:0006559 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0 0.2 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.1 GO:0000494 box C/D snoRNA 3'-end processing(GO:0000494) peptidyl-glutamine methylation(GO:0018364) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.0 0.6 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.2 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.5 GO:0071474 cellular hyperosmotic response(GO:0071474)
0.0 1.0 GO:0010390 histone monoubiquitination(GO:0010390)
0.0 0.1 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.0 0.1 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 1.1 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.5 GO:1903204 negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.0 0.3 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.3 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 0.1 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.2 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) regulation of endoribonuclease activity(GO:0060699) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 0.1 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.0 0.1 GO:0098759 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.0 0.1 GO:0060613 fat pad development(GO:0060613)
0.0 1.8 GO:0010965 regulation of mitotic sister chromatid separation(GO:0010965)
0.0 0.4 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.1 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.0 0.2 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.1 GO:0019060 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.2 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.2 GO:0060546 negative regulation of necroptotic process(GO:0060546)
0.0 0.4 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.3 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.3 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 1.1 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.1 GO:0070898 RNA polymerase III transcriptional preinitiation complex assembly(GO:0070898)
0.0 0.9 GO:0051904 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 0.9 GO:0017004 cytochrome complex assembly(GO:0017004)
0.0 0.9 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.7 GO:0006825 copper ion transport(GO:0006825)
0.0 1.4 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.1 GO:0071839 apoptotic process in bone marrow(GO:0071839)
0.0 0.6 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 1.8 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.1 GO:0061358 negative regulation of Wnt protein secretion(GO:0061358)
0.0 0.3 GO:0060539 diaphragm development(GO:0060539)
0.0 0.3 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.1 GO:2000252 negative regulation of behavior(GO:0048521) negative regulation of feeding behavior(GO:2000252)
0.0 0.1 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.0 0.1 GO:1901594 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.0 0.5 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.3 GO:0071313 cellular response to caffeine(GO:0071313)
0.0 1.1 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.5 GO:0006363 transcription elongation from RNA polymerase I promoter(GO:0006362) termination of RNA polymerase I transcription(GO:0006363)
0.0 0.4 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.1 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0 0.3 GO:0051984 positive regulation of chromosome segregation(GO:0051984)
0.0 0.2 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.2 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.0 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.0 0.2 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.6 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.5 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.6 GO:0048536 spleen development(GO:0048536)
0.0 0.4 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.1 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0 0.0 GO:0002551 mast cell chemotaxis(GO:0002551) mast cell migration(GO:0097531)
0.0 0.2 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.2 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.1 GO:0032400 melanosome localization(GO:0032400) pigment granule localization(GO:0051875)
0.0 0.3 GO:0006294 nucleotide-excision repair, preincision complex assembly(GO:0006294)
0.0 0.2 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.3 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.2 GO:0002349 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.0 0.1 GO:0045988 negative regulation of striated muscle contraction(GO:0045988) negative regulation of cardiac muscle contraction(GO:0055118)
0.0 0.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.1 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.3 GO:2000269 regulation of fibroblast apoptotic process(GO:2000269)
0.0 0.2 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.2 GO:0042723 thiamine-containing compound metabolic process(GO:0042723)
0.0 0.4 GO:0032332 positive regulation of chondrocyte differentiation(GO:0032332)
0.0 0.2 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.2 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.0 GO:0090045 positive regulation of deacetylase activity(GO:0090045)
0.0 0.1 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.1 GO:0009407 toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
0.0 0.1 GO:1901558 cellular response to vitamin E(GO:0071306) response to metformin(GO:1901558) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0 0.4 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.1 GO:0003190 atrioventricular valve formation(GO:0003190)
0.0 0.2 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.1 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.0 0.5 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 0.1 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.0 0.1 GO:0033385 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.0 0.1 GO:2000643 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966) positive regulation of early endosome to late endosome transport(GO:2000643)
0.0 0.1 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233) regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.2 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.3 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.2 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955)
0.0 0.1 GO:0038042 dimeric G-protein coupled receptor signaling pathway(GO:0038042)
0.0 0.3 GO:0045116 protein neddylation(GO:0045116)
0.0 0.1 GO:0018916 nitrobenzene metabolic process(GO:0018916)
0.0 0.2 GO:0006705 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.0 1.0 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.1 GO:0019530 taurine metabolic process(GO:0019530)
0.0 0.1 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.0 GO:0071442 regulation of histone H3-K14 acetylation(GO:0071440) positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.1 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 0.6 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.0 0.1 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.0 GO:0051598 meiotic recombination checkpoint(GO:0051598)
0.0 0.1 GO:0075713 establishment of integrated proviral latency(GO:0075713)
0.0 0.2 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.1 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 0.3 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.3 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.4 GO:0001893 maternal placenta development(GO:0001893)
0.0 0.1 GO:0086073 cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.0 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.0 0.4 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.1 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.0 0.3 GO:0019054 modulation by virus of host process(GO:0019054)
0.0 0.1 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.2 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.1 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.1 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.0 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.2 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.3 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.1 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 0.1 GO:2000698 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of epithelial cell differentiation involved in kidney development(GO:2000698) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.0 0.1 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 3.5 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 0.1 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.0 0.1 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.1 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.3 GO:0031297 replication fork processing(GO:0031297)
0.0 0.2 GO:0021554 optic nerve development(GO:0021554)
0.0 0.2 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.1 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.4 GO:0097503 sialylation(GO:0097503)
0.0 0.1 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.2 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.3 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.5 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.0 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.1 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:0021894 cerebral cortex GABAergic interneuron development(GO:0021894)
0.0 0.1 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.3 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.0 0.0 GO:0034059 response to anoxia(GO:0034059)
0.0 0.1 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.1 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:0045577 regulation of B cell differentiation(GO:0045577)
0.0 0.2 GO:0018023 peptidyl-lysine trimethylation(GO:0018023)
0.0 0.0 GO:0032650 regulation of interleukin-1 alpha production(GO:0032650)
0.0 0.2 GO:1901620 regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901620)
0.0 0.2 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.9 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.2 GO:0000394 RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394)
0.0 0.0 GO:0001807 type IV hypersensitivity(GO:0001806) regulation of type IV hypersensitivity(GO:0001807) negative regulation of type IV hypersensitivity(GO:0001808) negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865) negative regulation of hypersensitivity(GO:0002884)
0.0 0.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.0 GO:0050902 leukocyte adhesive activation(GO:0050902)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.7 GO:0030870 Mre11 complex(GO:0030870)
0.3 2.3 GO:1990393 3M complex(GO:1990393)
0.2 3.1 GO:0033093 Weibel-Palade body(GO:0033093)
0.2 0.7 GO:0043159 acrosomal matrix(GO:0043159)
0.2 0.9 GO:0070985 TFIIK complex(GO:0070985)
0.2 1.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.2 1.9 GO:0071438 invadopodium membrane(GO:0071438)
0.2 0.8 GO:0005879 axonemal microtubule(GO:0005879)
0.2 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 0.4 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.1 1.5 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 1.1 GO:0001940 male pronucleus(GO:0001940)
0.1 3.2 GO:0005614 interstitial matrix(GO:0005614)
0.1 1.1 GO:0043196 varicosity(GO:0043196)
0.1 0.9 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 2.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.5 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 1.4 GO:0036157 outer dynein arm(GO:0036157)
0.1 0.5 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.1 0.7 GO:0097179 protease inhibitor complex(GO:0097179)
0.1 0.3 GO:0042565 RNA nuclear export complex(GO:0042565)
0.1 0.3 GO:0005588 collagen type V trimer(GO:0005588)
0.1 2.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.3 GO:0031417 NatC complex(GO:0031417)
0.1 0.2 GO:0033150 cytoskeletal calyx(GO:0033150)
0.1 0.5 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.2 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 0.2 GO:0097447 dendritic tree(GO:0097447)
0.1 0.2 GO:0060203 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.1 0.2 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.1 0.4 GO:1990425 ryanodine receptor complex(GO:1990425)
0.1 0.4 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.1 0.3 GO:0036338 viral envelope(GO:0019031) viral membrane(GO:0036338)
0.1 0.2 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.1 0.6 GO:0005787 signal peptidase complex(GO:0005787)
0.1 0.3 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 0.3 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.1 0.3 GO:1990075 kinesin II complex(GO:0016939) periciliary membrane compartment(GO:1990075)
0.1 0.3 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.1 1.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.3 GO:0043293 apoptosome(GO:0043293)
0.1 0.3 GO:0000811 GINS complex(GO:0000811)
0.1 1.1 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 0.1 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
0.1 0.6 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.1 5.0 GO:0015030 Cajal body(GO:0015030)
0.1 0.2 GO:0034455 t-UTP complex(GO:0034455)
0.1 0.9 GO:0030478 actin cap(GO:0030478)
0.1 0.8 GO:0071141 SMAD protein complex(GO:0071141)
0.1 0.3 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 1.0 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.6 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.2 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.2 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 1.0 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.4 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.3 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.2 GO:0033263 CORVET complex(GO:0033263)
0.0 0.4 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.4 GO:0051286 cell tip(GO:0051286)
0.0 0.6 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.4 GO:0034464 BBSome(GO:0034464)
0.0 0.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.5 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.3 GO:0000125 PCAF complex(GO:0000125)
0.0 0.3 GO:0070852 cell body fiber(GO:0070852)
0.0 0.7 GO:0036038 MKS complex(GO:0036038)
0.0 0.3 GO:1990635 proximal dendrite(GO:1990635)
0.0 3.0 GO:0030684 preribosome(GO:0030684)
0.0 0.4 GO:0005916 fascia adherens(GO:0005916)
0.0 1.0 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.4 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.6 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.4 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.1 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.0 0.5 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.1 GO:0031310 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.0 1.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.2 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.2 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.8 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.4 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.0 1.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.4 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.4 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.5 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.3 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.2 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.2 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0 0.1 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.2 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.1 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 0.2 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.4 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.1 GO:0097441 basilar dendrite(GO:0097441)
0.0 0.1 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.4 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.4 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 2.0 GO:0018995 host(GO:0018995) host cell(GO:0043657)
0.0 0.4 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.1 GO:0070187 telosome(GO:0070187)
0.0 0.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.4 GO:0032059 bleb(GO:0032059)
0.0 0.1 GO:0071020 post-spliceosomal complex(GO:0071020)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.4 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.1 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.0 1.8 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.3 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.1 GO:0001534 radial spoke(GO:0001534)
0.0 1.5 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.7 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.5 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.1 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.3 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.3 GO:0010369 chromocenter(GO:0010369)
0.0 2.7 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.2 GO:0000243 commitment complex(GO:0000243)
0.0 2.3 GO:0043197 dendritic spine(GO:0043197)
0.0 0.1 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.8 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 3.2 GO:0031256 leading edge membrane(GO:0031256)
0.0 0.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.9 GO:0030863 cortical cytoskeleton(GO:0030863)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.0 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.0 1.1 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 0.1 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.8 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 1.4 GO:0005884 actin filament(GO:0005884)
0.0 0.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.1 GO:0031045 dense core granule(GO:0031045)
0.0 1.7 GO:0043296 apical junction complex(GO:0043296)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.0 GO:0001674 female germ cell nucleus(GO:0001674)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 8.7 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.5 1.5 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.4 1.3 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.4 1.2 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.4 0.4 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.4 1.2 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.4 3.0 GO:0032554 purine deoxyribonucleotide binding(GO:0032554)
0.4 2.3 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.4 2.5 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.4 1.1 GO:0002113 interleukin-33 binding(GO:0002113)
0.3 3.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.3 1.5 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.3 0.8 GO:0031862 prostanoid receptor binding(GO:0031862)
0.3 4.9 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.3 1.6 GO:0001594 trace-amine receptor activity(GO:0001594)
0.3 1.3 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.2 0.7 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.2 0.8 GO:0016295 oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297)
0.2 1.1 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.2 0.6 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.2 1.5 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 0.6 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.2 0.2 GO:0004913 interleukin-4 receptor activity(GO:0004913)
0.2 5.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 0.7 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.2 0.5 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.2 1.8 GO:0004849 uridine kinase activity(GO:0004849)
0.2 0.5 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.2 0.6 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.2 2.9 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.2 4.2 GO:0070403 NAD+ binding(GO:0070403)
0.2 0.6 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.1 0.4 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 0.7 GO:0048030 disaccharide binding(GO:0048030)
0.1 0.6 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.1 0.8 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.1 2.5 GO:0005549 odorant binding(GO:0005549)
0.1 0.4 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.1 0.5 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.1 0.3 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 0.8 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 0.4 GO:0035501 MH1 domain binding(GO:0035501)
0.1 0.7 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 1.0 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.1 1.1 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.1 2.5 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 0.7 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 2.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 3.1 GO:0031489 myosin V binding(GO:0031489)
0.1 2.0 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.6 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.1 0.7 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 0.7 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 0.3 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.1 0.8 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 0.3 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.1 0.4 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.1 0.4 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.1 0.7 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 0.9 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 0.4 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.5 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.9 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 0.4 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.1 0.3 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.1 0.6 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 0.3 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.1 1.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.3 GO:0061714 folic acid receptor activity(GO:0061714)
0.1 1.0 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 0.8 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.1 0.3 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.1 0.2 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.1 0.8 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1 0.2 GO:0070283 lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283)
0.1 0.3 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.2 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.1 0.2 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 0.5 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.1 0.5 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.2 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.1 0.4 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.1 0.4 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.7 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.4 GO:0004966 galanin receptor activity(GO:0004966)
0.1 1.1 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 2.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.2 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 1.4 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 0.2 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.1 0.4 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.1 0.3 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.1 0.3 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.1 0.6 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 0.2 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.1 2.6 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 0.3 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.1 0.3 GO:0004802 transketolase activity(GO:0004802)
0.1 0.3 GO:0004127 cytidylate kinase activity(GO:0004127)
0.1 0.2 GO:0030350 iron-responsive element binding(GO:0030350)
0.1 0.7 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.4 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 1.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 0.6 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 0.1 GO:0002134 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.1 0.2 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.1 0.4 GO:0050733 RS domain binding(GO:0050733)
0.1 0.2 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.1 0.2 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 0.4 GO:0000403 Y-form DNA binding(GO:0000403)
0.1 1.7 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 0.3 GO:0051185 coenzyme transporter activity(GO:0051185)
0.1 0.2 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 0.2 GO:0047322 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
0.1 0.8 GO:0089720 caspase binding(GO:0089720)
0.1 1.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 0.2 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1 0.2 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.1 1.1 GO:0070628 proteasome binding(GO:0070628)
0.1 0.7 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.2 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.1 0.3 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.2 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1 0.3 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.9 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 0.4 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 0.4 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 1.9 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 0.2 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.2 GO:0070363 mitochondrial light strand promoter sense binding(GO:0070363)
0.0 0.1 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 3.8 GO:0032813 tumor necrosis factor receptor superfamily binding(GO:0032813)
0.0 0.3 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.8 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.0 0.3 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.3 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.3 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.5 GO:0030884 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.0 0.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.2 GO:0016160 amylase activity(GO:0016160)
0.0 1.0 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.6 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.2 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.4 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.4 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 2.3 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.1 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.5 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.3 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.2 GO:0031716 calcitonin receptor binding(GO:0031716)
0.0 0.2 GO:0097643 amylin receptor activity(GO:0097643)
0.0 0.4 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.4 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.2 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.8 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.9 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.3 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.1 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 4.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.2 GO:0030109 HLA-B specific inhibitory MHC class I receptor activity(GO:0030109)
0.0 0.2 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.1 GO:1990259 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.0 0.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.7 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.2 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.0 0.4 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.4 GO:0060229 lipase activator activity(GO:0060229)
0.0 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.2 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.1 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.1 GO:0019959 interleukin-8 binding(GO:0019959)
0.0 0.2 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.1 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.0 0.4 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.3 GO:0004568 chitinase activity(GO:0004568)
0.0 0.1 GO:0001026 TFIIIB-type transcription factor activity(GO:0001026)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0004877 complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 1.0 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.7 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0004979 beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
0.0 0.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 1.2 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.6 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 1.0 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.1 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.2 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.0 0.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.7 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.2 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.4 GO:0031005 filamin binding(GO:0031005)
0.0 0.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.2 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 0.7 GO:0008200 ion channel inhibitor activity(GO:0008200)
0.0 0.1 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 1.6 GO:0034212 peptide N-acetyltransferase activity(GO:0034212)
0.0 0.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.4 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.4 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.3 GO:0042923 neuropeptide binding(GO:0042923)
0.0 1.3 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.1 GO:0016672 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.0 0.5 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.7 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.1 GO:0045518 interleukin-22 receptor binding(GO:0045518)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.1 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.3 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.2 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.0 1.7 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0035197 siRNA binding(GO:0035197)
0.0 0.3 GO:0043295 glutathione binding(GO:0043295)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.2 GO:0046870 cadmium ion binding(GO:0046870)
0.0 0.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.2 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.3 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.1 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.4 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.3 GO:0008494 translation activator activity(GO:0008494)
0.0 3.8 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.0 GO:0005124 scavenger receptor binding(GO:0005124)
0.0 0.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.5 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.7 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.1 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.1 GO:0061659 ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.0 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.0 0.0 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.0 0.0 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.4 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.0 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.0 0.6 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.2 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.2 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.3 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.1 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.2 GO:0005521 lamin binding(GO:0005521)
0.0 1.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.2 GO:0004707 MAP kinase activity(GO:0004707)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 7.8 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 5.3 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 1.6 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 0.4 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.1 1.8 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 3.2 PID BARD1 PATHWAY BARD1 signaling events
0.1 1.8 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 0.5 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 3.0 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.9 PID CD40 PATHWAY CD40/CD40L signaling
0.0 2.4 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 3.6 PID AURORA B PATHWAY Aurora B signaling
0.0 0.6 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 2.0 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.8 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.3 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 1.3 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.9 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 2.1 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.7 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.9 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.4 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.5 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.3 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.2 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.2 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 1.0 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.6 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.4 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 0.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.4 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.3 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.1 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.5 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 2.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.4 PID MYC PATHWAY C-MYC pathway
0.0 0.5 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 3.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.5 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.0 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.2 11.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.2 5.0 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 0.8 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.1 4.8 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 2.4 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 1.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 2.3 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 0.9 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 1.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 0.9 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 3.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 0.8 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 3.2 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 1.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 3.5 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 4.9 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 1.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 1.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 2.0 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 2.1 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.6 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.9 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 1.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 1.3 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.0 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 1.0 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 2.3 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 4.0 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.6 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.7 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.2 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 1.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.5 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 1.0 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.9 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.2 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.1 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.3 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.7 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.5 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.7 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.9 REACTOME DEFENSINS Genes involved in Defensins
0.0 1.0 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.8 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 1.3 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.4 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 0.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.3 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.7 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 6.0 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.1 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.2 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.7 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.3 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.2 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.7 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.2 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.7 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.6 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 3.0 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 2.0 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.8 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.6 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.0 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.3 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.1 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.6 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly