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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for POU3F3_POU3F4

Z-value: 0.84

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Transcription factors associated with POU3F3_POU3F4

Gene Symbol Gene ID Gene Info
POU3F3
ENSG00000198914.2 POU class 3 homeobox 3
POU3F4
ENSG00000196767.4 POU class 3 homeobox 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU3F4hg19_v2_chrX_+_82763265_827632830.433.2e-02Click!
POU3F3hg19_v2_chr2_+_105471969_1054719690.116.0e-01Click!

Activity profile of POU3F3_POU3F4 motif

Sorted Z-values of POU3F3_POU3F4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_169703203 3.32 ENST00000333360.7
ENST00000367781.4
ENST00000367782.4
ENST00000367780.4
ENST00000367779.4
SELE
selectin E
chr4_+_154622652 3.23 ENST00000260010.6
TLR2
toll-like receptor 2
chr6_+_127898312 3.00 ENST00000329722.7
C6orf58
chromosome 6 open reading frame 58
chr5_+_125758865 2.76 ENST00000542322.1
ENST00000544396.1
GRAMD3
GRAM domain containing 3
chr5_+_125758813 2.72 ENST00000285689.3
ENST00000515200.1
GRAMD3
GRAM domain containing 3
chr3_-_127455200 2.09 ENST00000398101.3
MGLL
monoglyceride lipase
chr3_-_107777208 2.08 ENST00000398258.3
CD47
CD47 molecule
chr6_+_29068386 2.05 ENST00000377171.3
OR2J1
olfactory receptor, family 2, subfamily J, member 1 (gene/pseudogene)
chr21_-_37914898 2.02 ENST00000399136.1
CLDN14
claudin 14
chr8_+_31497271 1.94 ENST00000520407.1
NRG1
neuregulin 1
chr2_+_161993465 1.85 ENST00000457476.1
TANK
TRAF family member-associated NFKB activator
chr10_-_49812997 1.81 ENST00000417912.2
ARHGAP22
Rho GTPase activating protein 22
chr19_-_44174330 1.76 ENST00000340093.3
PLAUR
plasminogen activator, urokinase receptor
chr2_-_220264703 1.72 ENST00000519905.1
ENST00000523282.1
ENST00000434339.1
ENST00000457935.1
DNPEP
aspartyl aminopeptidase
chr1_+_209602609 1.57 ENST00000458250.1
MIR205HG
MIR205 host gene (non-protein coding)
chr22_+_39101728 1.53 ENST00000216044.5
ENST00000484657.1
GTPBP1
GTP binding protein 1
chr22_+_30476163 1.45 ENST00000336726.6
HORMAD2
HORMA domain containing 2
chr2_+_161993412 1.41 ENST00000259075.2
ENST00000432002.1
TANK
TRAF family member-associated NFKB activator
chr10_-_49813090 1.41 ENST00000249601.4
ARHGAP22
Rho GTPase activating protein 22
chr6_-_154751629 1.40 ENST00000424998.1
CNKSR3
CNKSR family member 3
chr5_+_140762268 1.23 ENST00000518325.1
PCDHGA7
protocadherin gamma subfamily A, 7
chr19_-_44174305 1.22 ENST00000601723.1
ENST00000339082.3
PLAUR
plasminogen activator, urokinase receptor
chr4_+_158141899 1.17 ENST00000264426.9
ENST00000506284.1
GRIA2
glutamate receptor, ionotropic, AMPA 2
chr2_-_239140011 1.06 ENST00000409376.1
ENST00000409070.1
ENST00000409942.1
AC016757.3
Protein LOC151174
chr16_-_70835034 1.05 ENST00000261776.5
VAC14
Vac14 homolog (S. cerevisiae)
chr2_+_239335449 1.02 ENST00000264607.4
ASB1
ankyrin repeat and SOCS box containing 1
chr10_+_71561649 0.97 ENST00000398978.3
ENST00000354547.3
ENST00000357811.3
COL13A1
collagen, type XIII, alpha 1
chr6_-_46459675 0.97 ENST00000306764.7
RCAN2
regulator of calcineurin 2
chr1_-_89664595 0.97 ENST00000355754.6
GBP4
guanylate binding protein 4
chr11_-_102496063 0.90 ENST00000260228.2
MMP20
matrix metallopeptidase 20
chr3_-_58613323 0.90 ENST00000474531.1
ENST00000465970.1
FAM107A
family with sequence similarity 107, member A
chr2_-_239140276 0.90 ENST00000334973.4
AC016757.3
Protein LOC151174
chr8_+_61591337 0.88 ENST00000423902.2
CHD7
chromodomain helicase DNA binding protein 7
chr10_+_71561630 0.80 ENST00000398974.3
ENST00000398971.3
ENST00000398968.3
ENST00000398966.3
ENST00000398964.3
ENST00000398969.3
ENST00000356340.3
ENST00000398972.3
ENST00000398973.3
COL13A1
collagen, type XIII, alpha 1
chr3_+_111805182 0.80 ENST00000430855.1
ENST00000431717.2
ENST00000264848.5
C3orf52
chromosome 3 open reading frame 52
chr15_+_71228826 0.79 ENST00000558456.1
ENST00000560158.2
ENST00000558808.1
ENST00000559806.1
ENST00000559069.1
LRRC49
leucine rich repeat containing 49
chr7_-_115608304 0.79 ENST00000457268.1
TFEC
transcription factor EC
chr4_-_122085469 0.78 ENST00000057513.3
TNIP3
TNFAIP3 interacting protein 3
chr16_-_745946 0.78 ENST00000562563.1
FBXL16
F-box and leucine-rich repeat protein 16
chr3_-_112565703 0.77 ENST00000488794.1
CD200R1L
CD200 receptor 1-like
chr5_-_160279207 0.77 ENST00000327245.5
ATP10B
ATPase, class V, type 10B
chr5_+_140753444 0.77 ENST00000517434.1
PCDHGA6
protocadherin gamma subfamily A, 6
chr1_+_53925063 0.74 ENST00000371445.3
DMRTB1
DMRT-like family B with proline-rich C-terminal, 1
chr5_-_160973649 0.73 ENST00000393959.1
ENST00000517547.1
GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2
chr10_+_71561704 0.73 ENST00000520267.1
COL13A1
collagen, type XIII, alpha 1
chr12_+_113354341 0.73 ENST00000553152.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr8_+_31496809 0.72 ENST00000518104.1
ENST00000519301.1
NRG1
neuregulin 1
chr17_-_40540586 0.71 ENST00000264657.5
STAT3
signal transducer and activator of transcription 3 (acute-phase response factor)
chr7_+_119913688 0.70 ENST00000331113.4
KCND2
potassium voltage-gated channel, Shal-related subfamily, member 2
chrX_+_47053208 0.69 ENST00000442035.1
ENST00000457753.1
ENST00000335972.6
UBA1
ubiquitin-like modifier activating enzyme 1
chr12_+_21207503 0.67 ENST00000545916.1
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr3_-_112564797 0.66 ENST00000398214.1
ENST00000448932.1
CD200R1L
CD200 receptor 1-like
chr6_-_11779174 0.62 ENST00000379413.2
ADTRP
androgen-dependent TFPI-regulating protein
chr17_-_10452929 0.62 ENST00000532183.2
ENST00000397183.2
ENST00000420805.1
MYH2
myosin, heavy chain 2, skeletal muscle, adult
chr5_+_96212185 0.62 ENST00000379904.4
ERAP2
endoplasmic reticulum aminopeptidase 2
chr2_-_175711133 0.62 ENST00000409597.1
ENST00000413882.1
CHN1
chimerin 1
chr6_-_134861089 0.62 ENST00000606039.1
RP11-557H15.4
RP11-557H15.4
chr6_-_9933500 0.61 ENST00000492169.1
OFCC1
orofacial cleft 1 candidate 1
chr7_+_150065278 0.60 ENST00000519397.1
ENST00000479668.1
ENST00000540729.1
REPIN1
replication initiator 1
chr3_+_35722487 0.60 ENST00000441454.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr5_+_140529630 0.60 ENST00000543635.1
PCDHB6
protocadherin beta 6
chr1_-_111743285 0.59 ENST00000357640.4
DENND2D
DENN/MADD domain containing 2D
chr6_-_11779014 0.58 ENST00000229583.5
ADTRP
androgen-dependent TFPI-regulating protein
chr19_-_18508396 0.58 ENST00000595840.1
ENST00000339007.3
LRRC25
leucine rich repeat containing 25
chr15_+_69857515 0.57 ENST00000559477.1
RP11-279F6.1
RP11-279F6.1
chr4_-_168155577 0.57 ENST00000541354.1
ENST00000509854.1
ENST00000512681.1
ENST00000421836.2
ENST00000510741.1
ENST00000510403.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr4_-_168155730 0.56 ENST00000502330.1
ENST00000357154.3
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chrM_+_5824 0.55 ENST00000361624.2
MT-CO1
mitochondrially encoded cytochrome c oxidase I
chr5_+_140710061 0.55 ENST00000517417.1
ENST00000378105.3
PCDHGA1
protocadherin gamma subfamily A, 1
chrX_+_41548259 0.55 ENST00000378138.5
GPR34
G protein-coupled receptor 34
chr6_-_11779403 0.54 ENST00000414691.3
ADTRP
androgen-dependent TFPI-regulating protein
chr8_+_67039131 0.54 ENST00000315962.4
ENST00000353317.5
TRIM55
tripartite motif containing 55
chr17_-_49124230 0.54 ENST00000510283.1
ENST00000510855.1
SPAG9
sperm associated antigen 9
chr6_-_76782371 0.53 ENST00000369950.3
ENST00000369963.3
IMPG1
interphotoreceptor matrix proteoglycan 1
chr22_+_30477000 0.52 ENST00000403975.1
HORMAD2
HORMA domain containing 2
chr6_+_12717892 0.52 ENST00000379350.1
PHACTR1
phosphatase and actin regulator 1
chr14_+_21249200 0.51 ENST00000304677.2
RNASE6
ribonuclease, RNase A family, k6
chr12_-_42631529 0.51 ENST00000548917.1
YAF2
YY1 associated factor 2
chr5_-_146461027 0.50 ENST00000394410.2
ENST00000508267.1
ENST00000504198.1
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr11_-_57092381 0.50 ENST00000358252.3
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr1_+_244515930 0.50 ENST00000366537.1
ENST00000308105.4
C1orf100
chromosome 1 open reading frame 100
chr11_-_118305921 0.50 ENST00000532619.1
RP11-770J1.4
RP11-770J1.4
chr21_+_25801041 0.48 ENST00000453784.2
ENST00000423581.1
AP000476.1
AP000476.1
chr11_-_26593677 0.48 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr12_+_54892550 0.48 ENST00000545638.2
NCKAP1L
NCK-associated protein 1-like
chr7_-_107880508 0.47 ENST00000425651.2
NRCAM
neuronal cell adhesion molecule
chr8_-_119634141 0.47 ENST00000409003.4
ENST00000526328.1
ENST00000314727.4
ENST00000526765.1
SAMD12
sterile alpha motif domain containing 12
chr20_+_58179582 0.47 ENST00000371015.1
ENST00000395639.4
PHACTR3
phosphatase and actin regulator 3
chr2_+_90060377 0.46 ENST00000436451.2
IGKV6D-21
immunoglobulin kappa variable 6D-21 (non-functional)
chr10_+_114710425 0.46 ENST00000352065.5
ENST00000369395.1
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr9_-_34458531 0.45 ENST00000379089.1
ENST00000379087.1
ENST00000379084.1
ENST00000379081.1
ENST00000379080.1
ENST00000422409.1
ENST00000379078.1
ENST00000445726.1
ENST00000297620.4
FAM219A
family with sequence similarity 219, member A
chrX_+_41548220 0.45 ENST00000378142.4
GPR34
G protein-coupled receptor 34
chr13_+_109248500 0.45 ENST00000356711.2
MYO16
myosin XVI
chr16_-_21314360 0.45 ENST00000219599.3
ENST00000576703.1
CRYM
crystallin, mu
chr1_-_247921982 0.44 ENST00000408896.2
OR1C1
olfactory receptor, family 1, subfamily C, member 1
chr4_+_158142750 0.44 ENST00000505888.1
ENST00000449365.1
GRIA2
glutamate receptor, ionotropic, AMPA 2
chr1_+_50574585 0.44 ENST00000371824.1
ENST00000371823.4
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr4_-_175443943 0.43 ENST00000296522.6
HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr4_-_21950356 0.43 ENST00000447367.2
ENST00000382152.2
KCNIP4
Kv channel interacting protein 4
chr3_-_196242233 0.42 ENST00000397537.2
SMCO1
single-pass membrane protein with coiled-coil domains 1
chr5_+_149980622 0.42 ENST00000394243.1
SYNPO
synaptopodin
chr4_+_68424434 0.42 ENST00000265404.2
ENST00000396225.1
STAP1
signal transducing adaptor family member 1
chr20_+_48552908 0.41 ENST00000244061.2
RNF114
ring finger protein 114
chr6_+_26273144 0.41 ENST00000377733.2
HIST1H2BI
histone cluster 1, H2bi
chr3_-_155011483 0.40 ENST00000489090.1
RP11-451G4.2
RP11-451G4.2
chr10_+_97759848 0.39 ENST00000424464.1
ENST00000410012.2
ENST00000344386.3
CC2D2B
coiled-coil and C2 domain containing 2B
chr3_-_185826855 0.39 ENST00000306376.5
ETV5
ets variant 5
chr4_-_168155700 0.38 ENST00000357545.4
ENST00000512648.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr16_-_18887627 0.38 ENST00000563235.1
SMG1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr3_+_130569429 0.37 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr4_-_70826725 0.37 ENST00000353151.3
CSN2
casein beta
chr3_-_62359180 0.36 ENST00000283268.3
FEZF2
FEZ family zinc finger 2
chr6_+_30130969 0.35 ENST00000376694.4
TRIM15
tripartite motif containing 15
chr1_+_167298281 0.35 ENST00000367862.5
POU2F1
POU class 2 homeobox 1
chr19_+_39138271 0.35 ENST00000252699.2
ACTN4
actinin, alpha 4
chr17_-_64216748 0.35 ENST00000585162.1
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr15_+_64680003 0.34 ENST00000261884.3
TRIP4
thyroid hormone receptor interactor 4
chr3_+_159943362 0.34 ENST00000326474.3
C3orf80
chromosome 3 open reading frame 80
chr19_+_39138320 0.33 ENST00000424234.2
ENST00000390009.3
ENST00000589528.1
ACTN4
actinin, alpha 4
chr4_-_100575781 0.33 ENST00000511828.1
RP11-766F14.2
Protein LOC285556
chr17_-_41739283 0.33 ENST00000393661.2
ENST00000318579.4
MEOX1
mesenchyme homeobox 1
chr4_-_174451370 0.32 ENST00000359562.4
HAND2
heart and neural crest derivatives expressed 2
chr19_-_18632861 0.32 ENST00000262809.4
ELL
elongation factor RNA polymerase II
chr15_-_74658493 0.32 ENST00000419019.2
ENST00000569662.1
CYP11A1
cytochrome P450, family 11, subfamily A, polypeptide 1
chr17_-_40540484 0.32 ENST00000588969.1
STAT3
signal transducer and activator of transcription 3 (acute-phase response factor)
chr17_-_3301704 0.32 ENST00000322608.2
OR1E1
olfactory receptor, family 1, subfamily E, member 1
chr17_-_41738931 0.31 ENST00000329168.3
ENST00000549132.1
MEOX1
mesenchyme homeobox 1
chr13_-_46716969 0.31 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr17_-_38978847 0.31 ENST00000269576.5
KRT10
keratin 10
chr12_-_100486668 0.31 ENST00000550544.1
ENST00000551980.1
ENST00000548045.1
ENST00000545232.2
ENST00000551973.1
UHRF1BP1L
UHRF1 binding protein 1-like
chr1_+_101003687 0.30 ENST00000315033.4
GPR88
G protein-coupled receptor 88
chr5_+_101569696 0.30 ENST00000597120.1
AC008948.1
AC008948.1
chr16_+_1728257 0.30 ENST00000248098.3
ENST00000562684.1
ENST00000561516.1
ENST00000382711.5
ENST00000566742.1
HN1L
hematological and neurological expressed 1-like
chr7_+_134528635 0.30 ENST00000445569.2
CALD1
caldesmon 1
chr4_-_120243545 0.30 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr17_-_50236039 0.30 ENST00000451037.2
CA10
carbonic anhydrase X
chr1_-_2458026 0.30 ENST00000435556.3
ENST00000378466.3
PANK4
pantothenate kinase 4
chr8_-_59412717 0.30 ENST00000301645.3
CYP7A1
cytochrome P450, family 7, subfamily A, polypeptide 1
chr12_-_39734783 0.30 ENST00000552961.1
KIF21A
kinesin family member 21A
chr20_+_30555805 0.30 ENST00000562532.2
XKR7
XK, Kell blood group complex subunit-related family, member 7
chr3_+_153202284 0.29 ENST00000446603.2
C3orf79
chromosome 3 open reading frame 79
chr8_+_55528627 0.29 ENST00000220676.1
RP1
retinitis pigmentosa 1 (autosomal dominant)
chr6_-_32374900 0.29 ENST00000374995.3
ENST00000374993.1
ENST00000414363.1
ENST00000540315.1
ENST00000544175.1
ENST00000429232.2
ENST00000454136.3
ENST00000446536.2
BTNL2
butyrophilin-like 2 (MHC class II associated)
chr6_-_49712147 0.29 ENST00000433368.2
ENST00000354620.4
CRISP3
cysteine-rich secretory protein 3
chr1_+_28099683 0.29 ENST00000373943.4
STX12
syntaxin 12
chr5_+_119867159 0.29 ENST00000505123.1
PRR16
proline rich 16
chr19_-_44123734 0.28 ENST00000598676.1
ZNF428
zinc finger protein 428
chr11_+_33279850 0.28 ENST00000531504.1
ENST00000456517.1
HIPK3
homeodomain interacting protein kinase 3
chr11_-_104827425 0.28 ENST00000393150.3
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr6_-_49712123 0.28 ENST00000263045.4
CRISP3
cysteine-rich secretory protein 3
chr2_+_168043793 0.28 ENST00000409273.1
ENST00000409605.1
XIRP2
xin actin-binding repeat containing 2
chr1_+_101702417 0.27 ENST00000305352.6
S1PR1
sphingosine-1-phosphate receptor 1
chrX_+_72062617 0.27 ENST00000440247.1
DMRTC1B
DMRT-like family C1B
chr6_-_47277634 0.27 ENST00000296861.2
TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr11_+_55029628 0.27 ENST00000417545.2
TRIM48
tripartite motif containing 48
chr10_+_24738355 0.26 ENST00000307544.6
KIAA1217
KIAA1217
chr11_+_2405833 0.26 ENST00000527343.1
ENST00000464784.2
CD81
CD81 molecule
chr4_+_158141843 0.26 ENST00000509417.1
ENST00000296526.7
GRIA2
glutamate receptor, ionotropic, AMPA 2
chr10_-_75676400 0.26 ENST00000412307.2
C10orf55
chromosome 10 open reading frame 55
chr1_-_67142710 0.26 ENST00000502413.2
AL139147.1
Uncharacterized protein
chr5_+_140782351 0.25 ENST00000573521.1
PCDHGA9
protocadherin gamma subfamily A, 9
chr6_-_136847099 0.25 ENST00000438100.2
MAP7
microtubule-associated protein 7
chrX_-_119445306 0.25 ENST00000371369.4
ENST00000440464.1
ENST00000519908.1
TMEM255A
transmembrane protein 255A
chr7_-_108168580 0.25 ENST00000453085.1
PNPLA8
patatin-like phospholipase domain containing 8
chr5_+_34757309 0.25 ENST00000397449.1
RAI14
retinoic acid induced 14
chr5_-_11588907 0.25 ENST00000513598.1
ENST00000503622.1
CTNND2
catenin (cadherin-associated protein), delta 2
chrX_-_72097698 0.25 ENST00000373530.1
DMRTC1
DMRT-like family C1
chr1_+_212606219 0.25 ENST00000366988.3
NENF
neudesin neurotrophic factor
chr20_+_43990576 0.24 ENST00000372727.1
ENST00000414310.1
SYS1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr15_-_74658519 0.24 ENST00000450547.1
ENST00000358632.4
CYP11A1
cytochrome P450, family 11, subfamily A, polypeptide 1
chr7_-_14026063 0.24 ENST00000443608.1
ENST00000438956.1
ETV1
ets variant 1
chr1_+_207818460 0.23 ENST00000508064.2
CR1L
complement component (3b/4b) receptor 1-like
chr12_+_49297887 0.23 ENST00000266984.5
CCDC65
coiled-coil domain containing 65
chr1_+_6105974 0.23 ENST00000378083.3
KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr11_-_57004658 0.23 ENST00000606794.1
APLNR
apelin receptor
chr13_+_102142296 0.23 ENST00000376162.3
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chrX_+_23352133 0.23 ENST00000379361.4
PTCHD1
patched domain containing 1
chr8_-_67090825 0.23 ENST00000276571.3
CRH
corticotropin releasing hormone
chr19_+_34855925 0.22 ENST00000590375.1
ENST00000356487.5
GPI
glucose-6-phosphate isomerase
chr9_-_95244781 0.22 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
ASPN
asporin
chr10_+_85933494 0.22 ENST00000372126.3
C10orf99
chromosome 10 open reading frame 99
chr2_+_201170703 0.22 ENST00000358677.5
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr20_-_7921090 0.22 ENST00000378789.3
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chrX_+_15525426 0.22 ENST00000342014.6
BMX
BMX non-receptor tyrosine kinase
chr14_-_65409502 0.22 ENST00000389614.5
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr5_-_59481406 0.22 ENST00000546160.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr3_+_173116225 0.22 ENST00000457714.1
NLGN1
neuroligin 1
chr19_+_34855874 0.21 ENST00000588991.2
GPI
glucose-6-phosphate isomerase
chr15_-_76304731 0.21 ENST00000394907.3
NRG4
neuregulin 4
chr7_-_14880892 0.21 ENST00000406247.3
ENST00000399322.3
ENST00000258767.5
DGKB
diacylglycerol kinase, beta 90kDa
chr11_-_40314652 0.21 ENST00000527150.1
LRRC4C
leucine rich repeat containing 4C
chr2_-_88285309 0.21 ENST00000420840.2
RGPD2
RANBP2-like and GRIP domain containing 2
chr19_+_29493456 0.21 ENST00000591143.1
ENST00000592653.1
CTD-2081K17.2
CTD-2081K17.2
chr4_+_146403912 0.21 ENST00000507367.1
ENST00000394092.2
ENST00000515385.1
SMAD1
SMAD family member 1
chrX_+_57618269 0.21 ENST00000374888.1
ZXDB
zinc finger, X-linked, duplicated B
chr14_+_35747825 0.20 ENST00000540871.1
PSMA6
proteasome (prosome, macropain) subunit, alpha type, 6
chr14_-_47351391 0.20 ENST00000399222.3
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr3_-_131753830 0.20 ENST00000429747.1
CPNE4
copine IV
chr19_-_44124019 0.20 ENST00000300811.3
ZNF428
zinc finger protein 428
chr14_-_65409438 0.20 ENST00000557049.1
GPX2
glutathione peroxidase 2 (gastrointestinal)

Network of associatons between targets according to the STRING database.

First level regulatory network of POU3F3_POU3F4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0070340 central nervous system myelin formation(GO:0032289) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.7 3.0 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.5 3.3 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.4 2.7 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.3 1.2 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.3 0.9 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.3 2.1 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.3 0.9 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.2 2.0 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.2 0.7 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.1 0.4 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.1 0.4 GO:1903973 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.1 3.3 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 0.4 GO:1903487 regulation of lactation(GO:1903487)
0.1 0.5 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1 0.4 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.1 2.1 GO:0008228 opsonization(GO:0008228)
0.1 0.6 GO:0061056 somite specification(GO:0001757) sclerotome development(GO:0061056)
0.1 0.4 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 0.6 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1 0.2 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.1 0.3 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
0.1 0.4 GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.1 0.3 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.1 0.3 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.1 0.3 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 0.4 GO:0098728 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 0.5 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 0.3 GO:0061743 motor learning(GO:0061743)
0.1 0.3 GO:0003241 growth involved in heart morphogenesis(GO:0003241)
0.1 0.3 GO:0043128 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.1 2.0 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 1.5 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.2 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.1 0.4 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 0.4 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.2 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.1 0.2 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.0 0.1 GO:0071373 cellular response to luteinizing hormone stimulus(GO:0071373)
0.0 0.4 GO:2001300 lipoxin metabolic process(GO:2001300)
0.0 0.1 GO:0042700 luteinizing hormone signaling pathway(GO:0042700)
0.0 2.5 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.6 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.6 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.7 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.4 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 1.0 GO:0030539 male genitalia development(GO:0030539)
0.0 0.2 GO:0002282 microglial cell activation involved in immune response(GO:0002282) type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.1 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.0 1.5 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.0 0.7 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.0 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.0 0.2 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.3 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.1 GO:2000015 regulation of determination of dorsal identity(GO:2000015)
0.0 0.2 GO:0070995 NADPH oxidation(GO:0070995)
0.0 1.9 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.4 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.0 0.2 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.4 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.5 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.7 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.2 GO:1903301 fructose 2,6-bisphosphate metabolic process(GO:0006003) positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.2 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 0.3 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.2 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.8 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.3 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.3 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.0 0.2 GO:0032099 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.0 0.4 GO:0021794 thalamus development(GO:0021794)
0.0 2.5 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.2 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.5 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.6 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:1900165 negative regulation of interleukin-6 secretion(GO:1900165)
0.0 0.2 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.6 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 0.1 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154) positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.0 0.8 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.0 0.2 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.7 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 1.0 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.2 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0 0.2 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.6 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.2 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.3 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.5 GO:0031954 positive regulation of peptidyl-threonine phosphorylation(GO:0010800) positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.1 GO:0043091 L-arginine import(GO:0043091) arginine import(GO:0090467)
0.0 0.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.5 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.2 GO:0060856 establishment of blood-brain barrier(GO:0060856)
0.0 0.3 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 2.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.6 2.5 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.4 1.9 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.3 3.0 GO:0071438 invadopodium membrane(GO:0071438)
0.1 1.0 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 0.4 GO:0097444 spine apparatus(GO:0097444)
0.1 0.6 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 0.6 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 0.3 GO:0070195 growth hormone receptor complex(GO:0070195)
0.1 1.5 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 2.7 GO:0030673 axolemma(GO:0030673)
0.1 0.2 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.6 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.2 GO:1990423 RZZ complex(GO:1990423)
0.0 0.6 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 2.0 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.3 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.7 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.8 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.7 GO:0031143 pseudopodium(GO:0031143)
0.0 0.2 GO:0036020 endolysosome membrane(GO:0036020)
0.0 2.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.7 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.7 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.2 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.2 GO:0043219 lateral loop(GO:0043219)
0.0 1.8 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.1 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.3 GO:0042627 chylomicron(GO:0042627)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.3 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.7 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.5 3.3 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.4 3.2 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.3 2.7 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.2 3.3 GO:0033691 sialic acid binding(GO:0033691)
0.2 1.9 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.2 0.6 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.2 1.0 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.4 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.1 1.9 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 1.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 2.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.7 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.4 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.1 0.4 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.1 0.7 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.1 0.7 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.3 GO:0005148 prolactin receptor binding(GO:0005148)
0.1 2.1 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.2 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.1 0.7 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.2 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.1 0.3 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.2 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.1 0.5 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 1.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.4 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 0.2 GO:0015235 cobalamin transporter activity(GO:0015235)
0.0 0.3 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.5 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.7 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.6 GO:0045295 gamma-catenin binding(GO:0045295) armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.1 GO:0032427 GBD domain binding(GO:0032427)
0.0 0.7 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.8 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.6 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.3 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.5 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 2.5 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.2 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.3 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.3 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036) sphingolipid binding(GO:0046625)
0.0 0.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.1 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.4 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.6 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.3 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.2 GO:0070878 primary miRNA binding(GO:0070878)
0.0 0.6 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.6 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.7 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 0.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.8 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.2 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.1 GO:0035381 purinergic nucleotide receptor activity(GO:0001614) extracellular ATP-gated cation channel activity(GO:0004931) nucleotide receptor activity(GO:0016502) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.4 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 3.0 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 3.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 3.0 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 1.2 ST STAT3 PATHWAY STAT3 Pathway
0.0 2.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 2.1 NABA COLLAGENS Genes encoding collagen proteins
0.0 2.1 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 3.8 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.9 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.3 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.8 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.5 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.6 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.1 2.7 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 1.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 3.0 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1 3.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 0.4 REACTOME SIGNALING BY ERBB4 Genes involved in Signaling by ERBB4
0.1 2.0 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 1.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 1.9 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1 2.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 2.1 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.8 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 2.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.7 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.7 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 1.7 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 1.1 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.2 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.9 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.5 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 3.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins