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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for POU4F1_POU4F3

Z-value: 0.49

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Transcription factors associated with POU4F1_POU4F3

Gene Symbol Gene ID Gene Info
POU4F1
ENSG00000152192.6 POU class 4 homeobox 1
POU4F3
ENSG00000091010.4 POU class 4 homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU4F3hg19_v2_chr5_+_145718587_1457186070.116.1e-01Click!
POU4F1hg19_v2_chr13_-_79177673_791777010.077.4e-01Click!

Activity profile of POU4F1_POU4F3 motif

Sorted Z-values of POU4F1_POU4F3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_26108355 1.39 ENST00000338379.4
HIST1H1T
histone cluster 1, H1t
chr6_+_127898312 1.28 ENST00000329722.7
C6orf58
chromosome 6 open reading frame 58
chr22_+_30476163 1.08 ENST00000336726.6
HORMAD2
HORMA domain containing 2
chr21_-_37914898 0.97 ENST00000399136.1
CLDN14
claudin 14
chr22_+_39101728 0.91 ENST00000216044.5
ENST00000484657.1
GTPBP1
GTP binding protein 1
chr19_+_56368803 0.86 ENST00000587891.1
NLRP4
NLR family, pyrin domain containing 4
chr4_+_154622652 0.84 ENST00000260010.6
TLR2
toll-like receptor 2
chr22_+_30477000 0.79 ENST00000403975.1
HORMAD2
HORMA domain containing 2
chrX_+_47053208 0.75 ENST00000442035.1
ENST00000457753.1
ENST00000335972.6
UBA1
ubiquitin-like modifier activating enzyme 1
chr15_-_42264702 0.67 ENST00000220325.4
EHD4
EH-domain containing 4
chr1_-_33430286 0.61 ENST00000373456.7
ENST00000356990.5
ENST00000235150.4
RNF19B
ring finger protein 19B
chr1_+_50574585 0.52 ENST00000371824.1
ENST00000371823.4
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr20_+_30555805 0.51 ENST00000562532.2
XKR7
XK, Kell blood group complex subunit-related family, member 7
chr9_-_34458531 0.50 ENST00000379089.1
ENST00000379087.1
ENST00000379084.1
ENST00000379081.1
ENST00000379080.1
ENST00000422409.1
ENST00000379078.1
ENST00000445726.1
ENST00000297620.4
FAM219A
family with sequence similarity 219, member A
chr1_+_205197304 0.45 ENST00000358024.3
TMCC2
transmembrane and coiled-coil domain family 2
chr1_+_79115503 0.44 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
IFI44
interferon-induced protein 44
chr6_-_136847099 0.43 ENST00000438100.2
MAP7
microtubule-associated protein 7
chr19_+_39138320 0.42 ENST00000424234.2
ENST00000390009.3
ENST00000589528.1
ACTN4
actinin, alpha 4
chr6_-_136847610 0.41 ENST00000454590.1
ENST00000432797.2
MAP7
microtubule-associated protein 7
chr9_-_85882145 0.41 ENST00000328788.1
FRMD3
FERM domain containing 3
chr5_-_13944652 0.40 ENST00000265104.4
DNAH5
dynein, axonemal, heavy chain 5
chr19_+_39138271 0.39 ENST00000252699.2
ACTN4
actinin, alpha 4
chr14_+_22977587 0.39 ENST00000390504.1
TRAJ33
T cell receptor alpha joining 33
chr3_+_130569429 0.36 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr16_-_70835034 0.35 ENST00000261776.5
VAC14
Vac14 homolog (S. cerevisiae)
chr17_-_40540586 0.35 ENST00000264657.5
STAT3
signal transducer and activator of transcription 3 (acute-phase response factor)
chr19_+_48949030 0.35 ENST00000253237.5
GRWD1
glutamate-rich WD repeat containing 1
chr3_-_185826855 0.35 ENST00000306376.5
ETV5
ets variant 5
chr14_-_65409502 0.34 ENST00000389614.5
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr1_+_206808918 0.34 ENST00000367108.3
DYRK3
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
chr1_+_206808868 0.34 ENST00000367109.2
DYRK3
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
chr4_-_25032501 0.33 ENST00000382114.4
LGI2
leucine-rich repeat LGI family, member 2
chr3_-_167371740 0.32 ENST00000466760.1
ENST00000479765.1
WDR49
WD repeat domain 49
chr5_+_55149150 0.32 ENST00000297015.3
IL31RA
interleukin 31 receptor A
chr3_-_74570291 0.32 ENST00000263665.6
CNTN3
contactin 3 (plasmacytoma associated)
chr14_-_65409438 0.31 ENST00000557049.1
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr4_-_122085469 0.31 ENST00000057513.3
TNIP3
TNFAIP3 interacting protein 3
chr18_-_31803435 0.31 ENST00000589544.1
ENST00000269185.4
ENST00000261592.5
NOL4
nucleolar protein 4
chr2_-_88285309 0.30 ENST00000420840.2
RGPD2
RANBP2-like and GRIP domain containing 2
chr3_-_58613323 0.30 ENST00000474531.1
ENST00000465970.1
FAM107A
family with sequence similarity 107, member A
chr6_+_126102292 0.29 ENST00000368357.3
NCOA7
nuclear receptor coactivator 7
chr1_+_165864800 0.29 ENST00000469256.2
UCK2
uridine-cytidine kinase 2
chr7_-_115670792 0.28 ENST00000265440.7
ENST00000393485.1
TFEC
transcription factor EC
chr14_-_101036119 0.28 ENST00000355173.2
BEGAIN
brain-enriched guanylate kinase-associated
chr1_+_165864821 0.27 ENST00000470820.1
UCK2
uridine-cytidine kinase 2
chr2_+_185463093 0.27 ENST00000302277.6
ZNF804A
zinc finger protein 804A
chr3_+_35722487 0.26 ENST00000441454.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr22_-_30970560 0.26 ENST00000402369.1
ENST00000406361.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chr10_-_22292613 0.26 ENST00000376980.3
DNAJC1
DnaJ (Hsp40) homolog, subfamily C, member 1
chr1_-_197036364 0.26 ENST00000367412.1
F13B
coagulation factor XIII, B polypeptide
chr1_+_145293114 0.25 ENST00000369338.1
NBPF10
neuroblastoma breakpoint family, member 10
chr7_-_115670804 0.25 ENST00000320239.7
TFEC
transcription factor EC
chr7_-_107880508 0.24 ENST00000425651.2
NRCAM
neuronal cell adhesion molecule
chr2_-_26781521 0.24 ENST00000403946.3
ENST00000272371.2
OTOF
otoferlin
chr8_+_132916318 0.24 ENST00000254624.5
ENST00000522709.1
EFR3A
EFR3 homolog A (S. cerevisiae)
chr12_-_42631529 0.24 ENST00000548917.1
YAF2
YY1 associated factor 2
chr11_+_35211429 0.23 ENST00000525688.1
ENST00000278385.6
ENST00000533222.1
CD44
CD44 molecule (Indian blood group)
chr20_+_36405665 0.20 ENST00000373469.1
CTNNBL1
catenin, beta like 1
chr12_-_6798410 0.19 ENST00000361959.3
ENST00000436774.2
ENST00000544482.1
ZNF384
zinc finger protein 384
chr8_-_125577940 0.19 ENST00000519168.1
ENST00000395508.2
MTSS1
metastasis suppressor 1
chr12_-_6798523 0.18 ENST00000319770.3
ZNF384
zinc finger protein 384
chr17_+_18012020 0.18 ENST00000205890.5
MYO15A
myosin XVA
chr4_+_102711874 0.18 ENST00000508653.1
BANK1
B-cell scaffold protein with ankyrin repeats 1
chr1_-_160549235 0.17 ENST00000368054.3
ENST00000368048.3
ENST00000311224.4
ENST00000368051.3
ENST00000534968.1
CD84
CD84 molecule
chr5_+_119867159 0.17 ENST00000505123.1
PRR16
proline rich 16
chr20_+_30063067 0.17 ENST00000201979.2
REM1
RAS (RAD and GEM)-like GTP-binding 1
chr7_-_22234381 0.17 ENST00000458533.1
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr12_+_110011571 0.17 ENST00000539696.1
ENST00000228510.3
ENST00000392727.3
MVK
mevalonate kinase
chr4_-_68749699 0.17 ENST00000545541.1
TMPRSS11D
transmembrane protease, serine 11D
chr17_+_29664830 0.17 ENST00000444181.2
ENST00000417592.2
NF1
neurofibromin 1
chr6_+_12717892 0.16 ENST00000379350.1
PHACTR1
phosphatase and actin regulator 1
chr17_-_49124230 0.16 ENST00000510283.1
ENST00000510855.1
SPAG9
sperm associated antigen 9
chr4_+_159236462 0.16 ENST00000460056.2
RXFP1
relaxin/insulin-like family peptide receptor 1
chr12_-_6798616 0.16 ENST00000355772.4
ENST00000417772.3
ENST00000396801.3
ENST00000396799.2
ZNF384
zinc finger protein 384
chr5_+_129083772 0.16 ENST00000564719.1
KIAA1024L
KIAA1024-like
chr5_-_132200477 0.16 ENST00000296875.2
GDF9
growth differentiation factor 9
chr3_+_35722844 0.16 ENST00000436702.1
ENST00000438071.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr2_+_87135076 0.15 ENST00000409776.2
RGPD1
RANBP2-like and GRIP domain containing 1
chr3_+_35722424 0.15 ENST00000396481.2
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr10_+_33271469 0.15 ENST00000414157.1
RP11-462L8.1
RP11-462L8.1
chrX_+_65382433 0.15 ENST00000374727.3
HEPH
hephaestin
chr5_-_58295712 0.14 ENST00000317118.8
PDE4D
phosphodiesterase 4D, cAMP-specific
chr1_+_101003687 0.14 ENST00000315033.4
GPR88
G protein-coupled receptor 88
chr17_-_56492989 0.14 ENST00000583753.1
RNF43
ring finger protein 43
chr10_-_22292675 0.14 ENST00000376946.1
DNAJC1
DnaJ (Hsp40) homolog, subfamily C, member 1
chr9_-_123812542 0.14 ENST00000223642.1
C5
complement component 5
chr18_-_31803169 0.13 ENST00000590712.1
NOL4
nucleolar protein 4
chr22_-_43010928 0.13 ENST00000348657.2
ENST00000252115.5
POLDIP3
polymerase (DNA-directed), delta interacting protein 3
chr3_-_155011483 0.13 ENST00000489090.1
RP11-451G4.2
RP11-451G4.2
chr16_+_31366536 0.13 ENST00000562522.1
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr6_-_10115007 0.13 ENST00000485268.1
OFCC1
orofacial cleft 1 candidate 1
chr4_-_103998439 0.12 ENST00000503230.1
ENST00000503818.1
SLC9B2
solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
chr11_-_83393457 0.12 ENST00000404783.3
DLG2
discs, large homolog 2 (Drosophila)
chr11_+_120973375 0.12 ENST00000264037.2
TECTA
tectorin alpha
chr8_-_52721975 0.12 ENST00000356297.4
ENST00000543296.1
PXDNL
peroxidasin homolog (Drosophila)-like
chr7_-_5465045 0.12 ENST00000399434.2
TNRC18
trinucleotide repeat containing 18
chr6_-_44281043 0.12 ENST00000244571.4
AARS2
alanyl-tRNA synthetase 2, mitochondrial
chr9_+_135906076 0.12 ENST00000372097.5
ENST00000440319.1
GTF3C5
general transcription factor IIIC, polypeptide 5, 63kDa
chr12_+_49740700 0.12 ENST00000549441.2
ENST00000395069.3
DNAJC22
DnaJ (Hsp40) homolog, subfamily C, member 22
chr17_+_37783453 0.12 ENST00000579000.1
PPP1R1B
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr3_+_68055366 0.12 ENST00000496687.1
FAM19A1
family with sequence similarity 19 (chemokine (C-C motif)-like), member A1
chr4_+_74269956 0.12 ENST00000295897.4
ENST00000415165.2
ENST00000503124.1
ENST00000509063.1
ENST00000401494.3
ALB
albumin
chr19_+_54466179 0.12 ENST00000270458.2
CACNG8
calcium channel, voltage-dependent, gamma subunit 8
chr4_-_21546272 0.11 ENST00000509207.1
KCNIP4
Kv channel interacting protein 4
chr7_-_140482926 0.11 ENST00000496384.2
BRAF
v-raf murine sarcoma viral oncogene homolog B
chr5_+_112227311 0.11 ENST00000391338.1
ZRSR1
zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1
chr11_-_26593649 0.11 ENST00000455601.2
MUC15
mucin 15, cell surface associated
chr1_-_154580616 0.11 ENST00000368474.4
ADAR
adenosine deaminase, RNA-specific
chr11_+_36317830 0.11 ENST00000530639.1
PRR5L
proline rich 5 like
chr9_-_215744 0.11 ENST00000382387.2
C9orf66
chromosome 9 open reading frame 66
chr5_+_157158205 0.11 ENST00000231198.7
THG1L
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr18_+_28956740 0.11 ENST00000308128.4
ENST00000359747.4
DSG4
desmoglein 4
chr2_-_101034070 0.10 ENST00000264249.3
CHST10
carbohydrate sulfotransferase 10
chr17_+_37783170 0.10 ENST00000254079.4
PPP1R1B
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr2_-_209054709 0.10 ENST00000449053.1
ENST00000451346.1
ENST00000341287.4
C2orf80
chromosome 2 open reading frame 80
chr3_+_160939050 0.10 ENST00000493066.1
ENST00000351193.2
ENST00000472947.1
ENST00000463518.1
NMD3
NMD3 ribosome export adaptor
chr1_-_95538492 0.10 ENST00000370205.5
ALG14
ALG14, UDP-N-acetylglucosaminyltransferase subunit
chr22_+_17956618 0.09 ENST00000262608.8
CECR2
cat eye syndrome chromosome region, candidate 2
chr8_+_11666649 0.09 ENST00000528643.1
ENST00000525777.1
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr10_-_128359074 0.09 ENST00000544758.1
C10orf90
chromosome 10 open reading frame 90
chr6_-_161695074 0.09 ENST00000457520.2
ENST00000366906.5
ENST00000320285.4
AGPAT4
1-acylglycerol-3-phosphate O-acyltransferase 4
chr10_+_135207623 0.09 ENST00000317502.6
ENST00000432508.3
MTG1
mitochondrial ribosome-associated GTPase 1
chr6_-_161695042 0.09 ENST00000366908.5
ENST00000366911.5
ENST00000366905.3
AGPAT4
1-acylglycerol-3-phosphate O-acyltransferase 4
chr20_-_33872548 0.09 ENST00000374443.3
EIF6
eukaryotic translation initiation factor 6
chr20_-_1447547 0.09 ENST00000476071.1
NSFL1C
NSFL1 (p97) cofactor (p47)
chr2_+_197577841 0.09 ENST00000409270.1
CCDC150
coiled-coil domain containing 150
chrX_-_107975917 0.09 ENST00000563887.1
RP6-24A23.6
Uncharacterized protein
chr20_+_30102231 0.09 ENST00000335574.5
ENST00000340852.5
ENST00000398174.3
ENST00000376127.3
ENST00000344042.5
HM13
histocompatibility (minor) 13
chrX_+_41548259 0.09 ENST00000378138.5
GPR34
G protein-coupled receptor 34
chrX_+_65382381 0.09 ENST00000519389.1
HEPH
hephaestin
chr5_+_140767452 0.09 ENST00000519479.1
PCDHGB4
protocadherin gamma subfamily B, 4
chr22_+_31488433 0.09 ENST00000455608.1
SMTN
smoothelin
chr6_-_127840336 0.09 ENST00000525778.1
SOGA3
SOGA family member 3
chr2_+_182850743 0.09 ENST00000409702.1
PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chrX_-_15332665 0.08 ENST00000537676.1
ENST00000344384.4
ASB11
ankyrin repeat and SOCS box containing 11
chr20_-_1447467 0.08 ENST00000353088.2
ENST00000350991.4
NSFL1C
NSFL1 (p97) cofactor (p47)
chr13_-_103719196 0.08 ENST00000245312.3
SLC10A2
solute carrier family 10 (sodium/bile acid cotransporter), member 2
chr6_-_127840021 0.08 ENST00000465909.2
SOGA3
SOGA family member 3
chr1_+_145292806 0.08 ENST00000448873.2
NBPF10
neuroblastoma breakpoint family, member 10
chrX_+_23682379 0.08 ENST00000379349.1
PRDX4
peroxiredoxin 4
chr9_+_35673853 0.08 ENST00000378357.4
CA9
carbonic anhydrase IX
chr12_+_100750846 0.08 ENST00000323346.5
SLC17A8
solute carrier family 17 (vesicular glutamate transporter), member 8
chr14_-_80697396 0.08 ENST00000557010.1
DIO2
deiodinase, iodothyronine, type II
chr12_-_102224704 0.07 ENST00000299314.7
GNPTAB
N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr18_+_61575200 0.07 ENST00000238508.3
SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr12_-_49582978 0.07 ENST00000301071.7
TUBA1A
tubulin, alpha 1a
chr10_+_135207598 0.07 ENST00000477902.2
MTG1
mitochondrial ribosome-associated GTPase 1
chrX_+_41548220 0.07 ENST00000378142.4
GPR34
G protein-coupled receptor 34
chr17_-_40540484 0.07 ENST00000588969.1
STAT3
signal transducer and activator of transcription 3 (acute-phase response factor)
chr4_+_68424434 0.06 ENST00000265404.2
ENST00000396225.1
STAP1
signal transducing adaptor family member 1
chr5_-_59481406 0.06 ENST00000546160.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr1_-_108231101 0.06 ENST00000544443.1
ENST00000415432.2
VAV3
vav 3 guanine nucleotide exchange factor
chr16_-_85784557 0.06 ENST00000602675.1
C16orf74
chromosome 16 open reading frame 74
chrX_+_41583408 0.06 ENST00000302548.4
GPR82
G protein-coupled receptor 82
chr2_+_87144738 0.06 ENST00000559485.1
RGPD1
RANBP2-like and GRIP domain containing 1
chr16_+_619931 0.06 ENST00000321878.5
ENST00000439574.1
ENST00000026218.5
ENST00000470411.2
PIGQ
phosphatidylinositol glycan anchor biosynthesis, class Q
chr17_-_50236039 0.06 ENST00000451037.2
CA10
carbonic anhydrase X
chr17_-_72855989 0.06 ENST00000293190.5
GRIN2C
glutamate receptor, ionotropic, N-methyl D-aspartate 2C
chr2_+_182850551 0.06 ENST00000452904.1
ENST00000409137.3
ENST00000280295.3
PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr5_-_135290705 0.06 ENST00000274507.1
LECT2
leukocyte cell-derived chemotaxin 2
chr20_+_57875758 0.06 ENST00000395654.3
EDN3
endothelin 3
chr17_+_17685422 0.06 ENST00000395774.1
RAI1
retinoic acid induced 1
chr6_-_76782371 0.06 ENST00000369950.3
ENST00000369963.3
IMPG1
interphotoreceptor matrix proteoglycan 1
chr13_-_70682590 0.06 ENST00000377844.4
KLHL1
kelch-like family member 1
chr20_-_23731893 0.06 ENST00000398402.1
CST1
cystatin SN
chr9_+_131683174 0.05 ENST00000372592.3
ENST00000428610.1
PHYHD1
phytanoyl-CoA dioxygenase domain containing 1
chr2_+_161993412 0.05 ENST00000259075.2
ENST00000432002.1
TANK
TRAF family member-associated NFKB activator
chr17_-_40540377 0.05 ENST00000404395.3
ENST00000389272.3
ENST00000585517.1
ENST00000588065.1
STAT3
signal transducer and activator of transcription 3 (acute-phase response factor)
chr12_+_54366894 0.05 ENST00000546378.1
ENST00000243082.4
HOXC11
homeobox C11
chr17_-_38821373 0.05 ENST00000394052.3
KRT222
keratin 222
chr11_-_26593677 0.05 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr22_-_39268308 0.05 ENST00000407418.3
CBX6
chromobox homolog 6
chr19_-_36304201 0.05 ENST00000301175.3
PRODH2
proline dehydrogenase (oxidase) 2
chr16_-_51185172 0.04 ENST00000251020.4
SALL1
spalt-like transcription factor 1
chr5_-_35195338 0.04 ENST00000509839.1
PRLR
prolactin receptor
chr4_+_37962018 0.04 ENST00000504686.1
PTTG2
pituitary tumor-transforming 2
chr6_+_34204642 0.04 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1
high mobility group AT-hook 1
chr2_+_161993465 0.04 ENST00000457476.1
TANK
TRAF family member-associated NFKB activator
chr17_+_7155819 0.04 ENST00000570322.1
ENST00000576496.1
ENST00000574841.2
ELP5
elongator acetyltransferase complex subunit 5
chr14_+_39583427 0.04 ENST00000308317.6
ENST00000396249.2
ENST00000250379.8
ENST00000534684.2
ENST00000527381.1
GEMIN2
gem (nuclear organelle) associated protein 2
chrX_-_138724677 0.04 ENST00000370573.4
ENST00000338585.6
ENST00000370576.4
MCF2
MCF.2 cell line derived transforming sequence
chr7_+_99195677 0.04 ENST00000431679.1
GS1-259H13.2
GS1-259H13.2
chrX_-_138724994 0.04 ENST00000536274.1
MCF2
MCF.2 cell line derived transforming sequence
chr5_-_41261540 0.04 ENST00000263413.3
C6
complement component 6
chr7_-_20256965 0.04 ENST00000400331.5
ENST00000332878.4
MACC1
metastasis associated in colon cancer 1
chr12_-_89746173 0.04 ENST00000308385.6
DUSP6
dual specificity phosphatase 6
chrX_+_78003204 0.04 ENST00000435339.3
ENST00000514744.1
LPAR4
lysophosphatidic acid receptor 4
chr1_+_47603109 0.04 ENST00000371890.3
ENST00000294337.3
ENST00000371891.3
CYP4A22
cytochrome P450, family 4, subfamily A, polypeptide 22
chr10_-_112678904 0.03 ENST00000423273.1
ENST00000436562.1
ENST00000447005.1
ENST00000454061.1
BBIP1
BBSome interacting protein 1
chr17_-_29641084 0.03 ENST00000544462.1
EVI2B
ecotropic viral integration site 2B
chr10_-_115904361 0.03 ENST00000428953.1
ENST00000543782.1
C10orf118
chromosome 10 open reading frame 118
chr18_+_32397918 0.03 ENST00000590727.1
ENST00000601125.1
DTNA
dystrobrevin, alpha
chr14_-_106668095 0.03 ENST00000390606.2
IGHV3-20
immunoglobulin heavy variable 3-20
chr11_-_8290263 0.03 ENST00000428101.2
LMO1
LIM domain only 1 (rhombotin 1)
chr2_+_133874577 0.03 ENST00000596384.1
AC011755.1
HCG2006742; Protein LOC100996685
chr12_+_41831485 0.03 ENST00000539469.2
ENST00000298919.7
PDZRN4
PDZ domain containing ring finger 4
chr2_+_204732487 0.03 ENST00000302823.3
CTLA4
cytotoxic T-lymphocyte-associated protein 4
chr6_-_127840453 0.03 ENST00000556132.1
SOGA3
SOGA family member 3
chr14_-_107049312 0.03 ENST00000390627.2
IGHV3-53
immunoglobulin heavy variable 3-53
chr6_-_27880174 0.03 ENST00000303324.2
OR2B2
olfactory receptor, family 2, subfamily B, member 2

Network of associatons between targets according to the STRING database.

First level regulatory network of POU4F1_POU4F3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0032289 central nervous system myelin formation(GO:0032289) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.3 0.8 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.2 1.9 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.1 0.6 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.1 0.7 GO:0035617 stress granule disassembly(GO:0035617)
0.1 0.5 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.1 0.3 GO:0098728 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 0.4 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 0.2 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.2 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.1 0.2 GO:2000870 regulation of progesterone secretion(GO:2000870)
0.0 0.2 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.0 0.2 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.2 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 0.1 GO:0070898 RNA polymerase III transcriptional preinitiation complex assembly(GO:0070898)
0.0 0.1 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.0 0.1 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 0.2 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.2 GO:0030035 microspike assembly(GO:0030035)
0.0 1.0 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.3 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.2 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.1 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.3 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.2 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.1 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.0 1.0 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.2 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.2 GO:1900165 negative regulation of interleukin-6 secretion(GO:1900165)
0.0 0.7 GO:0006907 pinocytosis(GO:0006907)
0.0 0.4 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.1 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 0.0 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.0 0.5 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.0 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.0 0.4 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.3 GO:1903204 negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.0 0.0 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.2 GO:0045793 positive regulation of cell size(GO:0045793)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.1 0.6 GO:0044194 cytolytic granule(GO:0044194)
0.1 0.4 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.9 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.2 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 1.9 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.2 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.8 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0097450 astrocyte end-foot(GO:0097450)
0.0 0.8 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 1.4 GO:0000786 nucleosome(GO:0000786)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.2 GO:0043194 axon initial segment(GO:0043194)
0.0 0.1 GO:0005677 chromatin silencing complex(GO:0005677)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.8 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.2 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.1 0.6 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.5 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.1 GO:0001034 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003) RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.0 0.1 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.1 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.0 0.3 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.7 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.4 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 1.1 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.0 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.2 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.0 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.4 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.4 GO:0017091 AU-rich element binding(GO:0017091)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.8 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.9 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.8 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 1.0 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.6 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation