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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for POU5F1_POU2F3

Z-value: 1.31

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Transcription factors associated with POU5F1_POU2F3

Gene Symbol Gene ID Gene Info
ENSG00000204531.11 POU class 5 homeobox 1
ENSG00000137709.5 POU class 2 homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU5F1hg19_v2_chr6_-_31138439_311384750.331.1e-01Click!
POU2F3hg19_v2_chr11_+_120107344_1201073510.154.7e-01Click!

Activity profile of POU5F1_POU2F3 motif

Sorted Z-values of POU5F1_POU2F3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_61542922 8.39 ENST00000407417.3
nuclear factor I/A
chr1_+_61547405 7.95 ENST00000371189.4
nuclear factor I/A
chr4_-_186733363 6.36 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
sorbin and SH3 domain containing 2
chr1_+_61547894 6.03 ENST00000403491.3
nuclear factor I/A
chr1_+_228645796 4.29 ENST00000369160.2
histone cluster 3, H2bb
chr12_-_58212487 3.46 ENST00000549994.1
advillin
chr1_+_164528866 3.31 ENST00000420696.2
pre-B-cell leukemia homeobox 1
chr17_-_47841485 3.20 ENST00000506156.1
ENST00000240364.2
family with sequence similarity 117, member A
chr15_-_78526855 3.18 ENST00000541759.1
ENST00000558130.1
acyl-CoA synthetase bubblegum family member 1
chr10_-_105452917 3.09 ENST00000427662.2
SH3 and PX domains 2A
chr4_+_41614909 3.02 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIM and calponin homology domains 1
chr4_+_134070439 2.90 ENST00000264360.5
protocadherin 10
chr3_-_64211112 2.81 ENST00000295902.6
prickle homolog 2 (Drosophila)
chr16_-_30107491 2.79 ENST00000566134.1
ENST00000565110.1
ENST00000398841.1
ENST00000398838.4
yippee-like 3 (Drosophila)
chr9_-_140196703 2.73 ENST00000356628.2
NOTCH-regulated ankyrin repeat protein
chr1_-_153066998 2.67 ENST00000368750.3
small proline-rich protein 2E
chr22_+_23046750 2.63 ENST00000390307.2
immunoglobulin lambda variable 3-22 (gene/pseudogene)
chr8_+_56792377 2.62 ENST00000520220.2
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr18_+_72922710 2.58 ENST00000322038.5
teashirt zinc finger homeobox 1
chr12_-_42877726 2.50 ENST00000548696.1
prickle homolog 1 (Drosophila)
chr11_+_71238313 2.40 ENST00000398536.4
keratin associated protein 5-7
chr13_-_77460525 2.34 ENST00000377474.2
ENST00000317765.2
potassium channel tetramerization domain containing 12
chr2_+_89890533 2.32 ENST00000429992.2
immunoglobulin kappa variable 2D-40
chr8_+_56792355 2.30 ENST00000519728.1
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr4_+_41614720 2.26 ENST00000509277.1
LIM and calponin homology domains 1
chr5_-_111091948 2.22 ENST00000447165.2
neuronal regeneration related protein
chr12_-_42877764 2.21 ENST00000455697.1
prickle homolog 1 (Drosophila)
chr9_-_75567962 2.20 ENST00000297785.3
ENST00000376939.1
aldehyde dehydrogenase 1 family, member A1
chr18_+_8717369 2.10 ENST00000359865.3
ENST00000400050.3
ENST00000306285.7
SOGA family member 2
chr9_+_136325089 2.09 ENST00000291722.7
ENST00000316948.4
ENST00000540581.1
calcium channel flower domain containing 1
chr17_-_14683517 2.09 ENST00000379640.1
AC005863.1
chr2_+_120687335 2.05 ENST00000544261.1
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr1_+_33722080 1.93 ENST00000483388.1
ENST00000539719.1
zinc finger protein 362
chr2_-_225266711 1.90 ENST00000389874.3
family with sequence similarity 124B
chr3_+_132036243 1.90 ENST00000475741.1
ENST00000351273.7
acid phosphatase, prostate
chr4_-_99578776 1.86 ENST00000515287.1
tetraspanin 5
chr2_-_225266743 1.86 ENST00000409685.3
family with sequence similarity 124B
chr18_+_42260861 1.83 ENST00000282030.5
SET binding protein 1
chr7_-_27219849 1.79 ENST00000396344.4
homeobox A10
chr5_+_153570285 1.78 ENST00000425427.2
ENST00000297107.6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)
chr10_-_116286656 1.74 ENST00000428430.1
ENST00000369266.3
ENST00000392952.3
actin binding LIM protein 1
chr10_-_93392811 1.71 ENST00000238994.5
protein phosphatase 1, regulatory subunit 3C
chr1_+_6615241 1.65 ENST00000333172.6
ENST00000328191.4
ENST00000351136.3
taste receptor, type 1, member 1
chr13_+_32838801 1.64 ENST00000542859.1
furry homolog (Drosophila)
chr4_-_99578789 1.64 ENST00000511651.1
ENST00000505184.1
tetraspanin 5
chr7_+_135611542 1.61 ENST00000416501.1
AC015987.2
chr7_+_79764104 1.61 ENST00000351004.3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr4_-_123844084 1.58 ENST00000339154.2
nudix (nucleoside diphosphate linked moiety X)-type motif 6
chr6_-_111927062 1.57 ENST00000359831.4
TRAF3 interacting protein 2
chrX_-_62571220 1.51 ENST00000374884.2
spindlin family, member 4
chr5_-_172198190 1.45 ENST00000239223.3
dual specificity phosphatase 1
chr12_+_14518598 1.45 ENST00000261168.4
ENST00000538511.1
ENST00000545723.1
ENST00000543189.1
ENST00000536444.1
activating transcription factor 7 interacting protein
chrX_-_80457385 1.44 ENST00000451455.1
ENST00000436386.1
ENST00000358130.2
high mobility group nucleosome binding domain 5
chr1_+_87797351 1.43 ENST00000370542.1
LIM domain only 4
chr2_-_86094764 1.42 ENST00000393808.3
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr3_+_50192499 1.40 ENST00000413852.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr1_-_211752073 1.40 ENST00000367001.4
solute carrier family 30 (zinc transporter), member 1
chr22_+_31518938 1.40 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
inositol polyphosphate-5-phosphatase J
chr3_+_50192537 1.39 ENST00000002829.3
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr14_-_106453155 1.39 ENST00000390594.2
immunoglobulin heavy variable 1-2
chr14_-_92413727 1.38 ENST00000267620.10
fibulin 5
chrX_-_24665208 1.38 ENST00000356768.4
phosphate cytidylyltransferase 1, choline, beta
chr9_-_84303269 1.37 ENST00000418319.1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr14_+_22964877 1.35 ENST00000390494.1
T cell receptor alpha joining 43
chr1_+_32538492 1.33 ENST00000336294.5
transmembrane protein 39B
chr2_+_89998789 1.30 ENST00000453166.2
immunoglobulin kappa variable 2D-28
chr14_-_92413353 1.29 ENST00000556154.1
fibulin 5
chr9_-_74675521 1.28 ENST00000377024.3
chromosome 9 open reading frame 57
chr19_+_17337007 1.25 ENST00000215061.4
occludin/ELL domain containing 1
chr17_+_67410832 1.25 ENST00000590474.1
mitogen-activated protein kinase kinase 6
chr12_+_122064398 1.24 ENST00000330079.7
ORAI calcium release-activated calcium modulator 1
chr22_-_28197486 1.22 ENST00000302326.4
meningioma (disrupted in balanced translocation) 1
chr9_-_124991124 1.21 ENST00000394319.4
ENST00000340587.3
LIM homeobox 6
chr22_+_22936998 1.21 ENST00000390303.2
immunoglobulin lambda variable 3-32 (non-functional)
chr19_+_17337027 1.20 ENST00000601529.1
ENST00000600232.1
occludin/ELL domain containing 1
chr12_-_11062161 1.20 ENST00000390677.2
taste receptor, type 2, member 13
chr10_-_64576105 1.18 ENST00000242480.3
ENST00000411732.1
early growth response 2
chr11_-_2906979 1.17 ENST00000380725.1
ENST00000313407.6
ENST00000430149.2
ENST00000440480.2
ENST00000414822.3
cyclin-dependent kinase inhibitor 1C (p57, Kip2)
chr6_+_116691001 1.16 ENST00000537543.1
dermatan sulfate epimerase
chr11_-_27494309 1.16 ENST00000389858.4
leucine-rich repeat containing G protein-coupled receptor 4
chr7_-_130080977 1.15 ENST00000223208.5
centrosomal protein 41kDa
chr2_-_89521942 1.14 ENST00000482769.1
immunoglobulin kappa variable 2-28
chr4_+_140586922 1.13 ENST00000265498.1
ENST00000506797.1
microsomal glutathione S-transferase 2
chr1_+_201979645 1.13 ENST00000367284.5
ENST00000367283.3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr19_+_17337473 1.13 ENST00000598068.1
occludin/ELL domain containing 1
chr5_-_111092930 1.13 ENST00000257435.7
neuronal regeneration related protein
chr11_-_94964354 1.12 ENST00000536441.1
sestrin 3
chr11_-_27494279 1.12 ENST00000379214.4
leucine-rich repeat containing G protein-coupled receptor 4
chr17_+_38219063 1.11 ENST00000584985.1
ENST00000264637.4
ENST00000450525.2
thyroid hormone receptor, alpha
chr9_+_140172200 1.10 ENST00000357503.2
torsin family 4, member A
chr2_-_152684977 1.10 ENST00000428992.2
ENST00000295087.8
ADP-ribosylation factor-like 5A
chr19_+_17337406 1.09 ENST00000597836.1
occludin/ELL domain containing 1
chr14_+_103573853 1.06 ENST00000560304.1
exocyst complex component 3-like 4
chrX_+_80457442 1.05 ENST00000373212.5
SH3 domain binding glutamic acid-rich protein like
chr9_-_47314222 1.04 ENST00000420228.1
ENST00000438517.1
ENST00000414020.1
AL953854.2
chr3_-_66024213 1.03 ENST00000483466.1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr4_-_163085107 1.03 ENST00000379164.4
follistatin-like 5
chr5_-_39425222 1.03 ENST00000320816.6
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr5_-_39425290 1.02 ENST00000545653.1
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr19_+_21203481 1.02 ENST00000595401.1
zinc finger protein 430
chr1_+_32538520 1.02 ENST00000438825.1
ENST00000456834.2
ENST00000373634.4
ENST00000427288.1
transmembrane protein 39B
chr4_-_163085141 1.00 ENST00000427802.2
ENST00000306100.5
follistatin-like 5
chr3_+_107244229 1.00 ENST00000456419.1
ENST00000402163.2
bobby sox homolog (Drosophila)
chr14_-_92414055 1.00 ENST00000342058.4
fibulin 5
chr5_-_31532160 0.99 ENST00000511367.2
ENST00000513349.1
drosha, ribonuclease type III
chrX_-_48776292 0.98 ENST00000376509.4
pim-2 oncogene
chr3_+_49507674 0.96 ENST00000431960.1
ENST00000452317.1
ENST00000435508.2
ENST00000452060.1
ENST00000428779.1
ENST00000419218.1
ENST00000430636.1
dystroglycan 1 (dystrophin-associated glycoprotein 1)
chr14_-_106830057 0.95 ENST00000390616.2
immunoglobulin heavy variable 4-34
chr7_+_141490017 0.94 ENST00000247883.4
taste receptor, type 2, member 5
chr19_+_35417798 0.94 ENST00000303586.7
ENST00000439785.1
ENST00000601540.1
zinc finger protein 30
chr6_+_148663729 0.94 ENST00000367467.3
SAM and SH3 domain containing 1
chr14_-_106791536 0.93 ENST00000390613.2
immunoglobulin heavy variable 3-30
chr9_-_14180778 0.93 ENST00000380924.1
ENST00000543693.1
nuclear factor I/B
chr2_+_90060377 0.93 ENST00000436451.2
immunoglobulin kappa variable 6D-21 (non-functional)
chr4_-_134070250 0.93 ENST00000505289.1
ENST00000509715.1
RP11-9G1.3
chr7_+_150211918 0.92 ENST00000313543.4
GTPase, IMAP family member 7
chr16_-_11730213 0.90 ENST00000576334.1
ENST00000574848.1
lipopolysaccharide-induced TNF factor
chr12_+_43086018 0.90 ENST00000550177.1
RP11-25I15.3
chr2_-_152118352 0.89 ENST00000331426.5
RNA binding motif protein 43
chr2_-_89442621 0.89 ENST00000492167.1
immunoglobulin kappa variable 3-20
chr12_-_50616382 0.88 ENST00000552783.1
LIM domain and actin binding 1
chr2_+_136343820 0.88 ENST00000410054.1
R3H domain containing 1
chr3_-_168865522 0.88 ENST00000464456.1
MDS1 and EVI1 complex locus
chr9_+_2029019 0.87 ENST00000382194.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr7_+_102553430 0.86 ENST00000339431.4
ENST00000249377.4
leucine rich repeat containing 17
chr18_-_53089723 0.86 ENST00000561992.1
ENST00000562512.2
transcription factor 4
chr3_-_139396560 0.86 ENST00000514703.1
ENST00000511444.1
nicotinamide nucleotide adenylyltransferase 3
chr20_+_34802295 0.86 ENST00000432603.1
erythrocyte membrane protein band 4.1-like 1
chr7_-_14029283 0.86 ENST00000433547.1
ENST00000405192.2
ets variant 1
chr12_-_91574142 0.86 ENST00000547937.1
decorin
chrX_-_57164058 0.85 ENST00000374906.3
spindlin family, member 2A
chr8_-_93107696 0.85 ENST00000436581.2
ENST00000520583.1
ENST00000519061.1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr2_+_61108650 0.85 ENST00000295025.8
v-rel avian reticuloendotheliosis viral oncogene homolog
chr3_+_134514093 0.85 ENST00000398015.3
EPH receptor B1
chr18_-_52989217 0.85 ENST00000570287.2
transcription factor 4
chr14_-_106733624 0.85 ENST00000390610.2
immunoglobulin heavy variable 1-24
chr2_+_90077680 0.85 ENST00000390270.2
immunoglobulin kappa variable 3D-20
chr18_-_52989525 0.85 ENST00000457482.3
transcription factor 4
chr4_-_123843597 0.85 ENST00000510735.1
ENST00000304430.5
nudix (nucleoside diphosphate linked moiety X)-type motif 6
chr15_+_84116106 0.84 ENST00000535412.1
ENST00000324537.5
SH3-domain GRB2-like 3
chr19_+_17516531 0.84 ENST00000528911.1
ENST00000528604.1
ENST00000595892.1
ENST00000500836.2
ENST00000598546.1
ENST00000600369.1
ENST00000598356.1
ENST00000594426.1
multivesicular body subunit 12A
CTD-2521M24.9
chr15_-_20193370 0.84 ENST00000558565.2
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr16_-_49890016 0.84 ENST00000563137.2
zinc finger protein 423
chr10_-_72141330 0.84 ENST00000395011.1
ENST00000395010.1
leucine rich repeat containing 20
chr3_-_165555200 0.84 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
butyrylcholinesterase
chr1_-_154458520 0.84 ENST00000486773.1
Src homology 2 domain containing E
chr1_-_149783914 0.83 ENST00000369167.1
ENST00000427880.2
ENST00000545683.1
histone cluster 2, H2bf
chr5_+_153570319 0.82 ENST00000377661.2
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)
chr15_+_47476275 0.81 ENST00000558014.1
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr6_-_133119668 0.81 ENST00000275227.4
ENST00000538764.1
solute carrier family 18, subfamily B, member 1
chr6_-_26043885 0.80 ENST00000357905.2
histone cluster 1, H2bb
chr7_-_27205136 0.80 ENST00000396345.1
ENST00000343483.6
homeobox A9
chr17_-_46691990 0.80 ENST00000576562.1
homeobox B8
chr17_+_73084038 0.79 ENST00000578376.1
ENST00000329783.4
solute carrier family 16 (monocarboxylate transporter), member 5
chr14_-_106539557 0.79 ENST00000390599.2
immunoglobulin heavy variable 1-8
chr14_-_106805716 0.79 ENST00000438142.2
immunoglobulin heavy variable 4-31
chr19_-_41903161 0.79 ENST00000602129.1
ENST00000593771.1
ENST00000596905.1
ENST00000221233.4
exosome component 5
chr9_-_124990680 0.79 ENST00000541397.2
ENST00000560485.1
LIM homeobox 6
chr12_+_20963647 0.78 ENST00000381545.3
solute carrier organic anion transporter family, member 1B3
chr12_+_20963632 0.78 ENST00000540853.1
ENST00000261196.2
solute carrier organic anion transporter family, member 1B3
chr12_-_6772303 0.78 ENST00000396807.4
ENST00000446105.2
ENST00000341550.4
inhibitor of growth family, member 4
chr22_+_23213658 0.78 ENST00000390318.2
immunoglobulin lambda variable 4-3
chr20_+_306177 0.78 ENST00000544632.1
SRY (sex determining region Y)-box 12
chr5_-_73936451 0.78 ENST00000537006.1
ectodermal-neural cortex 1 (with BTB domain)
chr2_+_90108504 0.76 ENST00000390271.2
immunoglobulin kappa variable 6D-41 (non-functional)
chr17_+_62461569 0.76 ENST00000603557.1
ENST00000605096.1
mast cell immunoglobulin-like receptor 1
chr20_+_39657454 0.76 ENST00000361337.2
topoisomerase (DNA) I
chr8_-_104153703 0.75 ENST00000521246.1
chromosome 8 open reading frame 56
chr22_+_40573921 0.75 ENST00000454349.2
ENST00000335727.9
trinucleotide repeat containing 6B
chr19_+_17516624 0.75 ENST00000596322.1
ENST00000600008.1
ENST00000601885.1
CTD-2521M24.9
chr5_-_111092873 0.75 ENST00000509025.1
ENST00000515855.1
neuronal regeneration related protein
chr1_+_15272271 0.74 ENST00000400797.3
kazrin, periplakin interacting protein
chr12_-_123201337 0.74 ENST00000528880.2
hydroxycarboxylic acid receptor 3
chr12_-_68696652 0.74 ENST00000539972.1
Mdm1 nuclear protein homolog (mouse)
chr11_-_94965667 0.73 ENST00000542176.1
ENST00000278499.2
sestrin 3
chr2_-_211036051 0.73 ENST00000418791.1
ENST00000452086.1
ENST00000281772.9
KAT8 regulatory NSL complex subunit 1-like
chr4_-_90759440 0.72 ENST00000336904.3
synuclein, alpha (non A4 component of amyloid precursor)
chrX_-_106960285 0.72 ENST00000503515.1
ENST00000372397.2
TSC22 domain family, member 3
chr13_+_39612485 0.72 ENST00000379599.2
NHL repeat containing 3
chr11_+_112047087 0.72 ENST00000526088.1
ENST00000532593.1
ENST00000531169.1
beta-carotene oxygenase 2
chr15_+_57511609 0.71 ENST00000543579.1
ENST00000537840.1
ENST00000343827.3
transcription factor 12
chr6_-_52860171 0.70 ENST00000370963.4
glutathione S-transferase alpha 4
chr7_+_140378955 0.70 ENST00000473512.1
aarF domain containing kinase 2
chr8_+_96037255 0.69 ENST00000286687.4
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr20_+_306221 0.69 ENST00000342665.2
SRY (sex determining region Y)-box 12
chr21_+_39493560 0.69 ENST00000400477.3
ENST00000357704.4
Down syndrome critical region gene 8
chr7_-_44122063 0.69 ENST00000335195.6
ENST00000395831.3
ENST00000414235.1
ENST00000452049.1
ENST00000242248.5
polymerase (DNA directed), mu
chr8_+_96037205 0.69 ENST00000396124.4
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr7_+_64254793 0.69 ENST00000494380.1
ENST00000440155.2
ENST00000440598.1
ENST00000437743.1
zinc finger protein 138
chr15_+_39542867 0.68 ENST00000318578.3
ENST00000561223.1
chromosome 15 open reading frame 54
chr4_-_135122903 0.68 ENST00000421491.3
ENST00000529122.2
poly(A) binding protein, cytoplasmic 4-like
chr18_+_47088401 0.68 ENST00000261292.4
ENST00000427224.2
ENST00000580036.1
lipase, endothelial
chr9_+_77230499 0.68 ENST00000396204.2
RAR-related orphan receptor B
chr1_-_154832316 0.68 ENST00000361147.4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr10_+_23384435 0.67 ENST00000376510.3
methionine sulfoxide reductase B2
chr2_-_89247338 0.67 ENST00000496168.1
immunoglobulin kappa variable 1-5
chr2_+_198669365 0.67 ENST00000428675.1
phospholipase C-like 1
chr9_-_35080013 0.67 ENST00000378643.3
Fanconi anemia, complementation group G
chr17_+_73083816 0.67 ENST00000580123.1
ENST00000578847.1
solute carrier family 16 (monocarboxylate transporter), member 5
chr1_-_21377383 0.67 ENST00000374935.3
eukaryotic translation initiation factor 4 gamma, 3

Network of associatons between targets according to the STRING database.

First level regulatory network of POU5F1_POU2F3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.9 GO:0070666 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
1.2 4.7 GO:2000691 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
1.1 2.3 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.7 20.9 GO:0072189 ureter development(GO:0072189)
0.5 2.2 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.5 3.1 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.5 2.1 GO:0035026 leading edge cell differentiation(GO:0035026)
0.4 1.3 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.4 1.2 GO:0072709 cellular response to sorbitol(GO:0072709)
0.4 1.2 GO:0021569 rhombomere 3 development(GO:0021569) rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.4 1.5 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.4 1.1 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.4 1.8 GO:0060023 soft palate development(GO:0060023)
0.3 1.0 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.3 1.5 GO:0050917 sensory perception of umami taste(GO:0050917)
0.3 1.8 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.3 1.2 GO:0009956 radial pattern formation(GO:0009956)
0.3 3.7 GO:0048251 elastic fiber assembly(GO:0048251)
0.3 0.8 GO:0014016 neuroblast differentiation(GO:0014016)
0.3 2.4 GO:0014807 regulation of somitogenesis(GO:0014807)
0.3 0.3 GO:0070560 protein secretion by platelet(GO:0070560)
0.3 0.8 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.3 2.0 GO:0036484 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.2 0.7 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.2 0.7 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.2 0.7 GO:0042214 terpene metabolic process(GO:0042214)
0.2 1.8 GO:0021678 third ventricle development(GO:0021678)
0.2 0.7 GO:0046080 dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
0.2 1.1 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.2 7.0 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.2 1.6 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.2 0.6 GO:0050883 musculoskeletal movement, spinal reflex action(GO:0050883)
0.2 0.8 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.2 0.9 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.2 0.5 GO:0002384 hepatic immune response(GO:0002384)
0.2 0.5 GO:0005988 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.2 0.7 GO:0030807 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.2 0.7 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.2 0.8 GO:0019075 virus maturation(GO:0019075)
0.2 2.0 GO:0006657 CDP-choline pathway(GO:0006657)
0.2 0.8 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.1 1.8 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 0.7 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1 1.0 GO:0031642 negative regulation of myelination(GO:0031642)
0.1 0.7 GO:0051621 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
0.1 0.9 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.1 0.6 GO:0046373 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.1 1.4 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.1 1.1 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 0.7 GO:0035881 amacrine cell differentiation(GO:0035881)
0.1 0.9 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 1.8 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 2.6 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.1 4.8 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 1.0 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 1.6 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1 0.9 GO:0048539 bone marrow development(GO:0048539)
0.1 0.4 GO:0060940 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387) epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.1 0.6 GO:0035900 response to isolation stress(GO:0035900)
0.1 1.7 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.1 1.0 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.1 0.7 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.1 0.3 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.1 0.3 GO:0002731 negative regulation of dendritic cell cytokine production(GO:0002731) negative regulation of intracellular transport of viral material(GO:1901253)
0.1 0.4 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.5 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.7 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 0.3 GO:0060086 circadian temperature homeostasis(GO:0060086) positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.1 1.5 GO:0002115 store-operated calcium entry(GO:0002115)
0.1 0.4 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.1 1.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.4 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.6 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1 0.6 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 0.3 GO:0001172 transcription, RNA-templated(GO:0001172)
0.1 1.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.3 GO:0003289 atrial septum primum morphogenesis(GO:0003289) N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 0.3 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.1 12.9 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 0.4 GO:0030070 insulin processing(GO:0030070)
0.1 0.3 GO:1903028 positive regulation of opsonization(GO:1903028)
0.1 0.7 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.1 0.4 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.1 0.6 GO:0055095 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.1 0.2 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764)
0.1 2.3 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 1.1 GO:0060056 mammary gland involution(GO:0060056)
0.1 0.7 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.5 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.1 3.3 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.1 0.3 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.1 0.8 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 1.4 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 0.7 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.1 0.5 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 0.3 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.1 0.6 GO:1904885 mesenchymal cell differentiation involved in kidney development(GO:0072161) beta-catenin destruction complex assembly(GO:1904885) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.1 0.2 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 0.6 GO:0061525 hindgut development(GO:0061525)
0.1 0.8 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.1 0.2 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.1 1.9 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 0.1 GO:1900195 positive regulation of oocyte maturation(GO:1900195)
0.1 4.8 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.1 0.5 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.8 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 0.1 GO:0052314 phytoalexin metabolic process(GO:0052314)
0.1 0.2 GO:0035494 SNARE complex disassembly(GO:0035494)
0.1 0.5 GO:0002606 positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.1 0.3 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.2 GO:2000439 CD8-positive, alpha-beta T cell extravasation(GO:0035697) negative regulation of eosinophil activation(GO:1902567) regulation of T cell extravasation(GO:2000407) positive regulation of monocyte extravasation(GO:2000439) regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000449)
0.1 0.2 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.2 GO:0046125 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1 0.2 GO:0033385 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.1 0.3 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 2.4 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 0.5 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.1 0.2 GO:0060278 negative regulation of B cell differentiation(GO:0045578) regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.1 1.1 GO:0051601 exocyst localization(GO:0051601)
0.1 0.2 GO:1902896 terminal web assembly(GO:1902896)
0.1 0.8 GO:0040016 embryonic cleavage(GO:0040016)
0.1 0.2 GO:2000196 positive regulation of female gonad development(GO:2000196) regulation of progesterone secretion(GO:2000870)
0.1 1.2 GO:0007625 grooming behavior(GO:0007625)
0.1 1.7 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1 3.5 GO:0018149 peptide cross-linking(GO:0018149)
0.1 0.1 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.1 0.3 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.1 1.1 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 0.2 GO:0036510 trimming of terminal mannose on C branch(GO:0036510)
0.1 0.9 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.1 0.2 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 1.4 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.1 0.5 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.1 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.1 0.5 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.1 0.4 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 0.8 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.5 GO:0030091 protein repair(GO:0030091)
0.0 0.6 GO:0039530 MDA-5 signaling pathway(GO:0039530)
0.0 0.4 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.0 0.3 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.2 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.0 0.6 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:0034093 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0 0.2 GO:0060686 esophagus smooth muscle contraction(GO:0014846) negative regulation of prostatic bud formation(GO:0060686)
0.0 1.4 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.4 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.6 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 1.5 GO:2000811 negative regulation of anoikis(GO:2000811)
0.0 0.8 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 1.6 GO:0048305 immunoglobulin secretion(GO:0048305)
0.0 0.5 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.2 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.0 0.8 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.3 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.4 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.1 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0 0.1 GO:0035552 oxidative single-stranded DNA demethylation(GO:0035552)
0.0 0.4 GO:0072307 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0 0.2 GO:0018032 protein amidation(GO:0018032)
0.0 0.2 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.4 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.4 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.3 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.7 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.2 GO:0019303 D-ribose catabolic process(GO:0019303)
0.0 0.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.2 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.3 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.4 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.6 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.7 GO:0016180 snRNA processing(GO:0016180)
0.0 0.2 GO:0072423 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423) regulation of apoptotic DNA fragmentation(GO:1902510)
0.0 0.9 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 1.1 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.3 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.3 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.2 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.3 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.1 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740)
0.0 0.1 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.0 0.3 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.4 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 7.5 GO:0065004 protein-DNA complex assembly(GO:0065004)
0.0 0.2 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.0 0.5 GO:0035729 cellular response to hepatocyte growth factor stimulus(GO:0035729)
0.0 0.3 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.2 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 0.5 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.3 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.3 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.0 0.6 GO:0097369 sodium ion import(GO:0097369)
0.0 0.7 GO:0072662 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.2 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.4 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.3 GO:0043320 natural killer cell degranulation(GO:0043320)
0.0 0.0 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.3 GO:0033483 oxygen homeostasis(GO:0032364) gas homeostasis(GO:0033483)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 1.6 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.1 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.0 0.1 GO:0071494 cellular response to UV-C(GO:0071494)
0.0 0.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.1 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 0.5 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.3 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.4 GO:0071625 vocalization behavior(GO:0071625)
0.0 0.4 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.2 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.1 GO:1903314 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 0.1 GO:0019860 uracil metabolic process(GO:0019860)
0.0 0.1 GO:0042560 folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.0 0.1 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0 0.5 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.9 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.2 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.3 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.1 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 3.1 GO:0031424 keratinization(GO:0031424)
0.0 0.1 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.1 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 0.2 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.8 GO:0046039 GTP metabolic process(GO:0046039)
0.0 1.3 GO:0016239 positive regulation of macroautophagy(GO:0016239)
0.0 0.1 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.0 0.2 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 2.0 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.1 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.2 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.0 1.4 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.3 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.2 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.7 GO:0014911 positive regulation of smooth muscle cell migration(GO:0014911)
0.0 0.2 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.8 GO:1901661 quinone metabolic process(GO:1901661)
0.0 0.6 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.0 0.1 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.7 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.0 GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010)
0.0 0.3 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.5 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.1 GO:0038031 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 1.4 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.3 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.7 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.1 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.0 0.1 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 0.1 GO:0021815 modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration(GO:0021815) nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 1.0 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 1.6 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.1 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.1 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0 0.2 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.2 GO:0015871 choline transport(GO:0015871)
0.0 0.1 GO:1902969 mitotic DNA replication(GO:1902969)
0.0 0.2 GO:1902001 fatty acid transmembrane transport(GO:1902001)
0.0 0.0 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.0 0.4 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.6 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.1 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 0.1 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.1 GO:0002399 MHC protein complex assembly(GO:0002396) MHC class II protein complex assembly(GO:0002399)
0.0 0.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.1 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.3 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.5 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.0 GO:0009213 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.0 0.1 GO:0009629 response to gravity(GO:0009629)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.1 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.8 GO:0006968 cellular defense response(GO:0006968)
0.0 0.5 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.3 GO:1902186 regulation of viral release from host cell(GO:1902186)
0.0 0.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.9 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.4 3.7 GO:0071953 elastic fiber(GO:0071953)
0.3 0.9 GO:0071745 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.3 0.3 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.3 0.8 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.2 2.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.2 0.6 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.2 0.7 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.1 0.5 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.4 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 1.7 GO:0061700 GATOR2 complex(GO:0061700)
0.1 0.4 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.1 0.5 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 0.8 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.1 0.9 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560)
0.1 4.1 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 1.2 GO:0070938 contractile ring(GO:0070938)
0.1 1.2 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.6 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 0.5 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 0.9 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.7 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 0.9 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.8 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.1 0.6 GO:0071546 pi-body(GO:0071546)
0.1 3.9 GO:0001533 cornified envelope(GO:0001533)
0.1 0.2 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 0.2 GO:0043293 apoptosome(GO:0043293)
0.1 0.8 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.9 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 0.8 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 0.7 GO:0032039 integrator complex(GO:0032039)
0.0 0.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.3 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.3 GO:0031415 NatA complex(GO:0031415)
0.0 0.2 GO:0098536 deuterosome(GO:0098536)
0.0 0.2 GO:1990357 terminal web(GO:1990357)
0.0 0.3 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.3 GO:0097361 CIA complex(GO:0097361)
0.0 0.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.3 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 2.5 GO:0000786 nucleosome(GO:0000786)
0.0 0.9 GO:0071564 npBAF complex(GO:0071564)
0.0 0.2 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 2.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.4 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 1.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 4.8 GO:0032993 protein-DNA complex(GO:0032993)
0.0 2.1 GO:0002102 podosome(GO:0002102)
0.0 2.8 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 2.4 GO:0045095 keratin filament(GO:0045095)
0.0 0.2 GO:0032437 cuticular plate(GO:0032437)
0.0 6.3 GO:0030018 Z disc(GO:0030018)
0.0 0.1 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 0.2 GO:0033263 CORVET complex(GO:0033263)
0.0 1.2 GO:1902555 endoribonuclease complex(GO:1902555)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.4 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.9 GO:0000145 exocyst(GO:0000145)
0.0 1.2 GO:0030315 T-tubule(GO:0030315)
0.0 0.6 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.6 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.9 GO:0042629 mast cell granule(GO:0042629)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.1 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 2.6 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 3.3 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0097179 protease inhibitor complex(GO:0097179)
0.0 0.3 GO:0030904 retromer complex(GO:0030904)
0.0 0.1 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 1.8 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.4 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.2 GO:0031045 dense core granule(GO:0031045)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 2.2 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 1.3 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 0.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.1 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.1 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.4 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.4 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.0 GO:1990742 microvesicle(GO:1990742)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.6 GO:0043208 glycosphingolipid binding(GO:0043208)
0.5 1.5 GO:0052642 lysophosphatidic acid phosphatase activity(GO:0052642)
0.5 1.5 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.4 2.2 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.4 2.0 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.4 1.1 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.3 1.0 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.3 3.8 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 0.7 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.2 1.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.2 0.7 GO:0004170 dUTP diphosphatase activity(GO:0004170)
0.2 3.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.2 6.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 0.8 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.2 1.0 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.2 3.1 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2 2.7 GO:0030280 structural constituent of epidermis(GO:0030280)
0.2 2.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.2 0.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.6 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.1 0.7 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 0.9 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.1 0.6 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.1 1.4 GO:0034594 inositol-polyphosphate 5-phosphatase activity(GO:0004445) phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485) phosphatidylinositol trisphosphate phosphatase activity(GO:0034594)
0.1 0.7 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 1.6 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.5 GO:0004461 lactose synthase activity(GO:0004461)
0.1 1.1 GO:0043237 laminin-1 binding(GO:0043237)
0.1 1.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.1 0.5 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1 0.7 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.6 GO:0004925 prolactin receptor activity(GO:0004925)
0.1 2.6 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 1.7 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.3 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.1 0.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.3 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.1 0.8 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 1.7 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 0.3 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.1 0.5 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 1.5 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 2.4 GO:0008527 taste receptor activity(GO:0008527)
0.1 0.8 GO:0043426 MRF binding(GO:0043426)
0.1 0.6 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 0.9 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 1.3 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 0.8 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 0.8 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.2 GO:0004137 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.1 1.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 4.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 1.7 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 0.5 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 1.8 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.4 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 0.5 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.1 0.2 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.1 0.4 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.1 0.6 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.6 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.2 GO:0017129 triglyceride binding(GO:0017129)
0.1 13.2 GO:0003823 antigen binding(GO:0003823)
0.1 0.3 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.1 0.6 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.1 0.6 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.8 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.2 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 0.2 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.6 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.4 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 29.0 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1 1.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.5 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 1.8 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 0.2 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.3 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.1 0.2 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1 0.7 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.4 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.1 0.2 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 0.3 GO:0005499 vitamin D binding(GO:0005499)
0.0 1.1 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.8 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.8 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.7 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.2 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.9 GO:0005549 odorant binding(GO:0005549)
0.0 1.0 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 1.7 GO:0001972 retinoic acid binding(GO:0001972)
0.0 1.9 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.3 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.3 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.1 GO:0035514 DNA demethylase activity(GO:0035514)
0.0 0.4 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 0.1 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.2 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.3 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.9 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.4 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.2 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.5 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.1 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.3 GO:0008379 RNA polymerase III regulatory region DNA binding(GO:0001016) thioredoxin peroxidase activity(GO:0008379)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.7 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 1.5 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.7 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.1 GO:0042019 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 0.5 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.5 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.2 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.0 0.4 GO:0048156 tau protein binding(GO:0048156)
0.0 0.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.5 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 4.1 GO:0005178 integrin binding(GO:0005178)
0.0 1.1 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 1.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.1 GO:0030984 kininogen binding(GO:0030984)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.2 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 1.2 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 1.8 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.3 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.9 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.7 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.6 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.3 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.1 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.2 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.5 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.7 GO:0008276 protein methyltransferase activity(GO:0008276)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 1.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 1.3 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.0 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.1 GO:0008494 translation activator activity(GO:0008494)
0.0 0.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.8 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.1 GO:0045159 myosin II binding(GO:0045159)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 24.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 0.7 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 7.5 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.1 2.1 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 1.6 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 0.9 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 1.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 2.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.7 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.5 ST STAT3 PATHWAY STAT3 Pathway
0.0 1.0 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.3 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 1.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 4.5 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.9 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.7 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.7 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.8 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.8 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.2 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.1 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.0 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.8 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.2 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.2 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.4 PID E2F PATHWAY E2F transcription factor network
0.0 0.9 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 3.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.1 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.6 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.3 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.3 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.2 PID BARD1 PATHWAY BARD1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.9 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.2 2.9 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 2.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 1.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 1.6 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 5.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 1.6 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.1 2.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.7 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 2.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 1.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 0.8 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 1.9 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 1.1 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.6 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 2.4 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 1.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.2 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.8 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.3 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.1 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.6 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.8 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.1 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 1.4 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.7 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 2.9 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.5 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.4 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.5 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.6 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.6 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 1.2 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 1.0 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.5 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.5 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.8 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.4 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.0 0.9 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.4 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.1 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.6 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.7 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.5 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.5 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 1.1 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes