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Inflammatory response time course, HUVEC (Wada et al., 2009)
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Results for POU5F1_POU2F3
Z-value: 1.31
Motif logo
Transcription factors associated with POU5F1_POU2F3
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
POU5F1
|
ENSG00000204531.11 | POU class 5 homeobox 1 |
|
POU2F3
|
ENSG00000137709.5 | POU class 2 homeobox 3 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| POU5F1 | hg19_v2_chr6_-_31138439_31138475 | 0.33 | 1.1e-01 | Click! |
| POU2F3 | hg19_v2_chr11_+_120107344_120107351 | 0.15 | 4.7e-01 | Click! |
Activity profile of POU5F1_POU2F3 motif
Sorted Z-values of POU5F1_POU2F3 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr1_+_61542922 | 8.39 |
ENST00000407417.3
|
NFIA
|
nuclear factor I/A |
| chr1_+_61547405 | 7.95 |
ENST00000371189.4
|
NFIA
|
nuclear factor I/A |
| chr4_-_186733363 | 6.36 |
ENST00000393523.2
ENST00000393528.3 ENST00000449407.2 |
SORBS2
|
sorbin and SH3 domain containing 2 |
| chr1_+_61547894 | 6.03 |
ENST00000403491.3
|
NFIA
|
nuclear factor I/A |
| chr1_+_228645796 | 4.29 |
ENST00000369160.2
|
HIST3H2BB
|
histone cluster 3, H2bb |
| chr12_-_58212487 | 3.46 |
ENST00000549994.1
|
AVIL
|
advillin |
| chr1_+_164528866 | 3.31 |
ENST00000420696.2
|
PBX1
|
pre-B-cell leukemia homeobox 1 |
| chr17_-_47841485 | 3.20 |
ENST00000506156.1
ENST00000240364.2 |
FAM117A
|
family with sequence similarity 117, member A |
| chr15_-_78526855 | 3.18 |
ENST00000541759.1
ENST00000558130.1 |
ACSBG1
|
acyl-CoA synthetase bubblegum family member 1 |
| chr10_-_105452917 | 3.09 |
ENST00000427662.2
|
SH3PXD2A
|
SH3 and PX domains 2A |
| chr4_+_41614909 | 3.02 |
ENST00000509454.1
ENST00000396595.3 ENST00000381753.4 |
LIMCH1
|
LIM and calponin homology domains 1 |
| chr4_+_134070439 | 2.90 |
ENST00000264360.5
|
PCDH10
|
protocadherin 10 |
| chr3_-_64211112 | 2.81 |
ENST00000295902.6
|
PRICKLE2
|
prickle homolog 2 (Drosophila) |
| chr16_-_30107491 | 2.79 |
ENST00000566134.1
ENST00000565110.1 ENST00000398841.1 ENST00000398838.4 |
YPEL3
|
yippee-like 3 (Drosophila) |
| chr9_-_140196703 | 2.73 |
ENST00000356628.2
|
NRARP
|
NOTCH-regulated ankyrin repeat protein |
| chr1_-_153066998 | 2.67 |
ENST00000368750.3
|
SPRR2E
|
small proline-rich protein 2E |
| chr22_+_23046750 | 2.63 |
ENST00000390307.2
|
IGLV3-22
|
immunoglobulin lambda variable 3-22 (gene/pseudogene) |
| chr8_+_56792377 | 2.62 |
ENST00000520220.2
|
LYN
|
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog |
| chr18_+_72922710 | 2.58 |
ENST00000322038.5
|
TSHZ1
|
teashirt zinc finger homeobox 1 |
| chr12_-_42877726 | 2.50 |
ENST00000548696.1
|
PRICKLE1
|
prickle homolog 1 (Drosophila) |
| chr11_+_71238313 | 2.40 |
ENST00000398536.4
|
KRTAP5-7
|
keratin associated protein 5-7 |
| chr13_-_77460525 | 2.34 |
ENST00000377474.2
ENST00000317765.2 |
KCTD12
|
potassium channel tetramerization domain containing 12 |
| chr2_+_89890533 | 2.32 |
ENST00000429992.2
|
IGKV2D-40
|
immunoglobulin kappa variable 2D-40 |
| chr8_+_56792355 | 2.30 |
ENST00000519728.1
|
LYN
|
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog |
| chr4_+_41614720 | 2.26 |
ENST00000509277.1
|
LIMCH1
|
LIM and calponin homology domains 1 |
| chr5_-_111091948 | 2.22 |
ENST00000447165.2
|
NREP
|
neuronal regeneration related protein |
| chr12_-_42877764 | 2.21 |
ENST00000455697.1
|
PRICKLE1
|
prickle homolog 1 (Drosophila) |
| chr9_-_75567962 | 2.20 |
ENST00000297785.3
ENST00000376939.1 |
ALDH1A1
|
aldehyde dehydrogenase 1 family, member A1 |
| chr18_+_8717369 | 2.10 |
ENST00000359865.3
ENST00000400050.3 ENST00000306285.7 |
SOGA2
|
SOGA family member 2 |
| chr9_+_136325089 | 2.09 |
ENST00000291722.7
ENST00000316948.4 ENST00000540581.1 |
CACFD1
|
calcium channel flower domain containing 1 |
| chr17_-_14683517 | 2.09 |
ENST00000379640.1
|
AC005863.1
|
AC005863.1 |
| chr2_+_120687335 | 2.05 |
ENST00000544261.1
|
PTPN4
|
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) |
| chr1_+_33722080 | 1.93 |
ENST00000483388.1
ENST00000539719.1 |
ZNF362
|
zinc finger protein 362 |
| chr2_-_225266711 | 1.90 |
ENST00000389874.3
|
FAM124B
|
family with sequence similarity 124B |
| chr3_+_132036243 | 1.90 |
ENST00000475741.1
ENST00000351273.7 |
ACPP
|
acid phosphatase, prostate |
| chr4_-_99578776 | 1.86 |
ENST00000515287.1
|
TSPAN5
|
tetraspanin 5 |
| chr2_-_225266743 | 1.86 |
ENST00000409685.3
|
FAM124B
|
family with sequence similarity 124B |
| chr18_+_42260861 | 1.83 |
ENST00000282030.5
|
SETBP1
|
SET binding protein 1 |
| chr7_-_27219849 | 1.79 |
ENST00000396344.4
|
HOXA10
|
homeobox A10 |
| chr5_+_153570285 | 1.78 |
ENST00000425427.2
ENST00000297107.6 |
GALNT10
|
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10) |
| chr10_-_116286656 | 1.74 |
ENST00000428430.1
ENST00000369266.3 ENST00000392952.3 |
ABLIM1
|
actin binding LIM protein 1 |
| chr10_-_93392811 | 1.71 |
ENST00000238994.5
|
PPP1R3C
|
protein phosphatase 1, regulatory subunit 3C |
| chr1_+_6615241 | 1.65 |
ENST00000333172.6
ENST00000328191.4 ENST00000351136.3 |
TAS1R1
|
taste receptor, type 1, member 1 |
| chr13_+_32838801 | 1.64 |
ENST00000542859.1
|
FRY
|
furry homolog (Drosophila) |
| chr4_-_99578789 | 1.64 |
ENST00000511651.1
ENST00000505184.1 |
TSPAN5
|
tetraspanin 5 |
| chr7_+_135611542 | 1.61 |
ENST00000416501.1
|
AC015987.2
|
AC015987.2 |
| chr7_+_79764104 | 1.61 |
ENST00000351004.3
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 |
| chr4_-_123844084 | 1.58 |
ENST00000339154.2
|
NUDT6
|
nudix (nucleoside diphosphate linked moiety X)-type motif 6 |
| chr6_-_111927062 | 1.57 |
ENST00000359831.4
|
TRAF3IP2
|
TRAF3 interacting protein 2 |
| chrX_-_62571220 | 1.51 |
ENST00000374884.2
|
SPIN4
|
spindlin family, member 4 |
| chr5_-_172198190 | 1.45 |
ENST00000239223.3
|
DUSP1
|
dual specificity phosphatase 1 |
| chr12_+_14518598 | 1.45 |
ENST00000261168.4
ENST00000538511.1 ENST00000545723.1 ENST00000543189.1 ENST00000536444.1 |
ATF7IP
|
activating transcription factor 7 interacting protein |
| chrX_-_80457385 | 1.44 |
ENST00000451455.1
ENST00000436386.1 ENST00000358130.2 |
HMGN5
|
high mobility group nucleosome binding domain 5 |
| chr1_+_87797351 | 1.43 |
ENST00000370542.1
|
LMO4
|
LIM domain only 4 |
| chr2_-_86094764 | 1.42 |
ENST00000393808.3
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| chr3_+_50192499 | 1.40 |
ENST00000413852.1
|
SEMA3F
|
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
| chr1_-_211752073 | 1.40 |
ENST00000367001.4
|
SLC30A1
|
solute carrier family 30 (zinc transporter), member 1 |
| chr22_+_31518938 | 1.40 |
ENST00000412985.1
ENST00000331075.5 ENST00000412277.2 ENST00000420017.1 ENST00000400294.2 ENST00000405300.1 ENST00000404390.3 |
INPP5J
|
inositol polyphosphate-5-phosphatase J |
| chr3_+_50192537 | 1.39 |
ENST00000002829.3
|
SEMA3F
|
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
| chr14_-_106453155 | 1.39 |
ENST00000390594.2
|
IGHV1-2
|
immunoglobulin heavy variable 1-2 |
| chr14_-_92413727 | 1.38 |
ENST00000267620.10
|
FBLN5
|
fibulin 5 |
| chrX_-_24665208 | 1.38 |
ENST00000356768.4
|
PCYT1B
|
phosphate cytidylyltransferase 1, choline, beta |
| chr9_-_84303269 | 1.37 |
ENST00000418319.1
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
| chr14_+_22964877 | 1.35 |
ENST00000390494.1
|
TRAJ43
|
T cell receptor alpha joining 43 |
| chr1_+_32538492 | 1.33 |
ENST00000336294.5
|
TMEM39B
|
transmembrane protein 39B |
| chr2_+_89998789 | 1.30 |
ENST00000453166.2
|
IGKV2D-28
|
immunoglobulin kappa variable 2D-28 |
| chr14_-_92413353 | 1.29 |
ENST00000556154.1
|
FBLN5
|
fibulin 5 |
| chr9_-_74675521 | 1.28 |
ENST00000377024.3
|
C9orf57
|
chromosome 9 open reading frame 57 |
| chr19_+_17337007 | 1.25 |
ENST00000215061.4
|
OCEL1
|
occludin/ELL domain containing 1 |
| chr17_+_67410832 | 1.25 |
ENST00000590474.1
|
MAP2K6
|
mitogen-activated protein kinase kinase 6 |
| chr12_+_122064398 | 1.24 |
ENST00000330079.7
|
ORAI1
|
ORAI calcium release-activated calcium modulator 1 |
| chr22_-_28197486 | 1.22 |
ENST00000302326.4
|
MN1
|
meningioma (disrupted in balanced translocation) 1 |
| chr9_-_124991124 | 1.21 |
ENST00000394319.4
ENST00000340587.3 |
LHX6
|
LIM homeobox 6 |
| chr22_+_22936998 | 1.21 |
ENST00000390303.2
|
IGLV3-32
|
immunoglobulin lambda variable 3-32 (non-functional) |
| chr19_+_17337027 | 1.20 |
ENST00000601529.1
ENST00000600232.1 |
OCEL1
|
occludin/ELL domain containing 1 |
| chr12_-_11062161 | 1.20 |
ENST00000390677.2
|
TAS2R13
|
taste receptor, type 2, member 13 |
| chr10_-_64576105 | 1.18 |
ENST00000242480.3
ENST00000411732.1 |
EGR2
|
early growth response 2 |
| chr11_-_2906979 | 1.17 |
ENST00000380725.1
ENST00000313407.6 ENST00000430149.2 ENST00000440480.2 ENST00000414822.3 |
CDKN1C
|
cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| chr6_+_116691001 | 1.16 |
ENST00000537543.1
|
DSE
|
dermatan sulfate epimerase |
| chr11_-_27494309 | 1.16 |
ENST00000389858.4
|
LGR4
|
leucine-rich repeat containing G protein-coupled receptor 4 |
| chr7_-_130080977 | 1.15 |
ENST00000223208.5
|
CEP41
|
centrosomal protein 41kDa |
| chr2_-_89521942 | 1.14 |
ENST00000482769.1
|
IGKV2-28
|
immunoglobulin kappa variable 2-28 |
| chr4_+_140586922 | 1.13 |
ENST00000265498.1
ENST00000506797.1 |
MGST2
|
microsomal glutathione S-transferase 2 |
| chr1_+_201979645 | 1.13 |
ENST00000367284.5
ENST00000367283.3 |
ELF3
|
E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
| chr19_+_17337473 | 1.13 |
ENST00000598068.1
|
OCEL1
|
occludin/ELL domain containing 1 |
| chr5_-_111092930 | 1.13 |
ENST00000257435.7
|
NREP
|
neuronal regeneration related protein |
| chr11_-_94964354 | 1.12 |
ENST00000536441.1
|
SESN3
|
sestrin 3 |
| chr11_-_27494279 | 1.12 |
ENST00000379214.4
|
LGR4
|
leucine-rich repeat containing G protein-coupled receptor 4 |
| chr17_+_38219063 | 1.11 |
ENST00000584985.1
ENST00000264637.4 ENST00000450525.2 |
THRA
|
thyroid hormone receptor, alpha |
| chr9_+_140172200 | 1.10 |
ENST00000357503.2
|
TOR4A
|
torsin family 4, member A |
| chr2_-_152684977 | 1.10 |
ENST00000428992.2
ENST00000295087.8 |
ARL5A
|
ADP-ribosylation factor-like 5A |
| chr19_+_17337406 | 1.09 |
ENST00000597836.1
|
OCEL1
|
occludin/ELL domain containing 1 |
| chr14_+_103573853 | 1.06 |
ENST00000560304.1
|
EXOC3L4
|
exocyst complex component 3-like 4 |
| chrX_+_80457442 | 1.05 |
ENST00000373212.5
|
SH3BGRL
|
SH3 domain binding glutamic acid-rich protein like |
| chr9_-_47314222 | 1.04 |
ENST00000420228.1
ENST00000438517.1 ENST00000414020.1 |
AL953854.2
|
AL953854.2 |
| chr3_-_66024213 | 1.03 |
ENST00000483466.1
|
MAGI1
|
membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| chr4_-_163085107 | 1.03 |
ENST00000379164.4
|
FSTL5
|
follistatin-like 5 |
| chr5_-_39425222 | 1.03 |
ENST00000320816.6
|
DAB2
|
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
| chr5_-_39425290 | 1.02 |
ENST00000545653.1
|
DAB2
|
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
| chr19_+_21203481 | 1.02 |
ENST00000595401.1
|
ZNF430
|
zinc finger protein 430 |
| chr1_+_32538520 | 1.02 |
ENST00000438825.1
ENST00000456834.2 ENST00000373634.4 ENST00000427288.1 |
TMEM39B
|
transmembrane protein 39B |
| chr4_-_163085141 | 1.00 |
ENST00000427802.2
ENST00000306100.5 |
FSTL5
|
follistatin-like 5 |
| chr3_+_107244229 | 1.00 |
ENST00000456419.1
ENST00000402163.2 |
BBX
|
bobby sox homolog (Drosophila) |
| chr14_-_92414055 | 1.00 |
ENST00000342058.4
|
FBLN5
|
fibulin 5 |
| chr5_-_31532160 | 0.99 |
ENST00000511367.2
ENST00000513349.1 |
DROSHA
|
drosha, ribonuclease type III |
| chrX_-_48776292 | 0.98 |
ENST00000376509.4
|
PIM2
|
pim-2 oncogene |
| chr3_+_49507674 | 0.96 |
ENST00000431960.1
ENST00000452317.1 ENST00000435508.2 ENST00000452060.1 ENST00000428779.1 ENST00000419218.1 ENST00000430636.1 |
DAG1
|
dystroglycan 1 (dystrophin-associated glycoprotein 1) |
| chr14_-_106830057 | 0.95 |
ENST00000390616.2
|
IGHV4-34
|
immunoglobulin heavy variable 4-34 |
| chr7_+_141490017 | 0.94 |
ENST00000247883.4
|
TAS2R5
|
taste receptor, type 2, member 5 |
| chr19_+_35417798 | 0.94 |
ENST00000303586.7
ENST00000439785.1 ENST00000601540.1 |
ZNF30
|
zinc finger protein 30 |
| chr6_+_148663729 | 0.94 |
ENST00000367467.3
|
SASH1
|
SAM and SH3 domain containing 1 |
| chr14_-_106791536 | 0.93 |
ENST00000390613.2
|
IGHV3-30
|
immunoglobulin heavy variable 3-30 |
| chr9_-_14180778 | 0.93 |
ENST00000380924.1
ENST00000543693.1 |
NFIB
|
nuclear factor I/B |
| chr2_+_90060377 | 0.93 |
ENST00000436451.2
|
IGKV6D-21
|
immunoglobulin kappa variable 6D-21 (non-functional) |
| chr4_-_134070250 | 0.93 |
ENST00000505289.1
ENST00000509715.1 |
RP11-9G1.3
|
RP11-9G1.3 |
| chr7_+_150211918 | 0.92 |
ENST00000313543.4
|
GIMAP7
|
GTPase, IMAP family member 7 |
| chr16_-_11730213 | 0.90 |
ENST00000576334.1
ENST00000574848.1 |
LITAF
|
lipopolysaccharide-induced TNF factor |
| chr12_+_43086018 | 0.90 |
ENST00000550177.1
|
RP11-25I15.3
|
RP11-25I15.3 |
| chr2_-_152118352 | 0.89 |
ENST00000331426.5
|
RBM43
|
RNA binding motif protein 43 |
| chr2_-_89442621 | 0.89 |
ENST00000492167.1
|
IGKV3-20
|
immunoglobulin kappa variable 3-20 |
| chr12_-_50616382 | 0.88 |
ENST00000552783.1
|
LIMA1
|
LIM domain and actin binding 1 |
| chr2_+_136343820 | 0.88 |
ENST00000410054.1
|
R3HDM1
|
R3H domain containing 1 |
| chr3_-_168865522 | 0.88 |
ENST00000464456.1
|
MECOM
|
MDS1 and EVI1 complex locus |
| chr9_+_2029019 | 0.87 |
ENST00000382194.1
|
SMARCA2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
| chr7_+_102553430 | 0.86 |
ENST00000339431.4
ENST00000249377.4 |
LRRC17
|
leucine rich repeat containing 17 |
| chr18_-_53089723 | 0.86 |
ENST00000561992.1
ENST00000562512.2 |
TCF4
|
transcription factor 4 |
| chr3_-_139396560 | 0.86 |
ENST00000514703.1
ENST00000511444.1 |
NMNAT3
|
nicotinamide nucleotide adenylyltransferase 3 |
| chr20_+_34802295 | 0.86 |
ENST00000432603.1
|
EPB41L1
|
erythrocyte membrane protein band 4.1-like 1 |
| chr7_-_14029283 | 0.86 |
ENST00000433547.1
ENST00000405192.2 |
ETV1
|
ets variant 1 |
| chr12_-_91574142 | 0.86 |
ENST00000547937.1
|
DCN
|
decorin |
| chrX_-_57164058 | 0.85 |
ENST00000374906.3
|
SPIN2A
|
spindlin family, member 2A |
| chr8_-_93107696 | 0.85 |
ENST00000436581.2
ENST00000520583.1 ENST00000519061.1 |
RUNX1T1
|
runt-related transcription factor 1; translocated to, 1 (cyclin D-related) |
| chr2_+_61108650 | 0.85 |
ENST00000295025.8
|
REL
|
v-rel avian reticuloendotheliosis viral oncogene homolog |
| chr3_+_134514093 | 0.85 |
ENST00000398015.3
|
EPHB1
|
EPH receptor B1 |
| chr18_-_52989217 | 0.85 |
ENST00000570287.2
|
TCF4
|
transcription factor 4 |
| chr14_-_106733624 | 0.85 |
ENST00000390610.2
|
IGHV1-24
|
immunoglobulin heavy variable 1-24 |
| chr2_+_90077680 | 0.85 |
ENST00000390270.2
|
IGKV3D-20
|
immunoglobulin kappa variable 3D-20 |
| chr18_-_52989525 | 0.85 |
ENST00000457482.3
|
TCF4
|
transcription factor 4 |
| chr4_-_123843597 | 0.85 |
ENST00000510735.1
ENST00000304430.5 |
NUDT6
|
nudix (nucleoside diphosphate linked moiety X)-type motif 6 |
| chr15_+_84116106 | 0.84 |
ENST00000535412.1
ENST00000324537.5 |
SH3GL3
|
SH3-domain GRB2-like 3 |
| chr19_+_17516531 | 0.84 |
ENST00000528911.1
ENST00000528604.1 ENST00000595892.1 ENST00000500836.2 ENST00000598546.1 ENST00000600369.1 ENST00000598356.1 ENST00000594426.1 |
MVB12A
CTD-2521M24.9
|
multivesicular body subunit 12A CTD-2521M24.9 |
| chr15_-_20193370 | 0.84 |
ENST00000558565.2
|
IGHV3OR15-7
|
immunoglobulin heavy variable 3/OR15-7 (pseudogene) |
| chr16_-_49890016 | 0.84 |
ENST00000563137.2
|
ZNF423
|
zinc finger protein 423 |
| chr10_-_72141330 | 0.84 |
ENST00000395011.1
ENST00000395010.1 |
LRRC20
|
leucine rich repeat containing 20 |
| chr3_-_165555200 | 0.84 |
ENST00000479451.1
ENST00000540653.1 ENST00000488954.1 ENST00000264381.3 |
BCHE
|
butyrylcholinesterase |
| chr1_-_154458520 | 0.84 |
ENST00000486773.1
|
SHE
|
Src homology 2 domain containing E |
| chr1_-_149783914 | 0.83 |
ENST00000369167.1
ENST00000427880.2 ENST00000545683.1 |
HIST2H2BF
|
histone cluster 2, H2bf |
| chr5_+_153570319 | 0.82 |
ENST00000377661.2
|
GALNT10
|
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10) |
| chr15_+_47476275 | 0.81 |
ENST00000558014.1
|
SEMA6D
|
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D |
| chr6_-_133119668 | 0.81 |
ENST00000275227.4
ENST00000538764.1 |
SLC18B1
|
solute carrier family 18, subfamily B, member 1 |
| chr6_-_26043885 | 0.80 |
ENST00000357905.2
|
HIST1H2BB
|
histone cluster 1, H2bb |
| chr7_-_27205136 | 0.80 |
ENST00000396345.1
ENST00000343483.6 |
HOXA9
|
homeobox A9 |
| chr17_-_46691990 | 0.80 |
ENST00000576562.1
|
HOXB8
|
homeobox B8 |
| chr17_+_73084038 | 0.79 |
ENST00000578376.1
ENST00000329783.4 |
SLC16A5
|
solute carrier family 16 (monocarboxylate transporter), member 5 |
| chr14_-_106539557 | 0.79 |
ENST00000390599.2
|
IGHV1-8
|
immunoglobulin heavy variable 1-8 |
| chr14_-_106805716 | 0.79 |
ENST00000438142.2
|
IGHV4-31
|
immunoglobulin heavy variable 4-31 |
| chr19_-_41903161 | 0.79 |
ENST00000602129.1
ENST00000593771.1 ENST00000596905.1 ENST00000221233.4 |
EXOSC5
|
exosome component 5 |
| chr9_-_124990680 | 0.79 |
ENST00000541397.2
ENST00000560485.1 |
LHX6
|
LIM homeobox 6 |
| chr12_+_20963647 | 0.78 |
ENST00000381545.3
|
SLCO1B3
|
solute carrier organic anion transporter family, member 1B3 |
| chr12_+_20963632 | 0.78 |
ENST00000540853.1
ENST00000261196.2 |
SLCO1B3
|
solute carrier organic anion transporter family, member 1B3 |
| chr12_-_6772303 | 0.78 |
ENST00000396807.4
ENST00000446105.2 ENST00000341550.4 |
ING4
|
inhibitor of growth family, member 4 |
| chr22_+_23213658 | 0.78 |
ENST00000390318.2
|
IGLV4-3
|
immunoglobulin lambda variable 4-3 |
| chr20_+_306177 | 0.78 |
ENST00000544632.1
|
SOX12
|
SRY (sex determining region Y)-box 12 |
| chr5_-_73936451 | 0.78 |
ENST00000537006.1
|
ENC1
|
ectodermal-neural cortex 1 (with BTB domain) |
| chr2_+_90108504 | 0.76 |
ENST00000390271.2
|
IGKV6D-41
|
immunoglobulin kappa variable 6D-41 (non-functional) |
| chr17_+_62461569 | 0.76 |
ENST00000603557.1
ENST00000605096.1 |
MILR1
|
mast cell immunoglobulin-like receptor 1 |
| chr20_+_39657454 | 0.76 |
ENST00000361337.2
|
TOP1
|
topoisomerase (DNA) I |
| chr8_-_104153703 | 0.75 |
ENST00000521246.1
|
C8orf56
|
chromosome 8 open reading frame 56 |
| chr22_+_40573921 | 0.75 |
ENST00000454349.2
ENST00000335727.9 |
TNRC6B
|
trinucleotide repeat containing 6B |
| chr19_+_17516624 | 0.75 |
ENST00000596322.1
ENST00000600008.1 ENST00000601885.1 |
CTD-2521M24.9
|
CTD-2521M24.9 |
| chr5_-_111092873 | 0.75 |
ENST00000509025.1
ENST00000515855.1 |
NREP
|
neuronal regeneration related protein |
| chr1_+_15272271 | 0.74 |
ENST00000400797.3
|
KAZN
|
kazrin, periplakin interacting protein |
| chr12_-_123201337 | 0.74 |
ENST00000528880.2
|
HCAR3
|
hydroxycarboxylic acid receptor 3 |
| chr12_-_68696652 | 0.74 |
ENST00000539972.1
|
MDM1
|
Mdm1 nuclear protein homolog (mouse) |
| chr11_-_94965667 | 0.73 |
ENST00000542176.1
ENST00000278499.2 |
SESN3
|
sestrin 3 |
| chr2_-_211036051 | 0.73 |
ENST00000418791.1
ENST00000452086.1 ENST00000281772.9 |
KANSL1L
|
KAT8 regulatory NSL complex subunit 1-like |
| chr4_-_90759440 | 0.72 |
ENST00000336904.3
|
SNCA
|
synuclein, alpha (non A4 component of amyloid precursor) |
| chrX_-_106960285 | 0.72 |
ENST00000503515.1
ENST00000372397.2 |
TSC22D3
|
TSC22 domain family, member 3 |
| chr13_+_39612485 | 0.72 |
ENST00000379599.2
|
NHLRC3
|
NHL repeat containing 3 |
| chr11_+_112047087 | 0.72 |
ENST00000526088.1
ENST00000532593.1 ENST00000531169.1 |
BCO2
|
beta-carotene oxygenase 2 |
| chr15_+_57511609 | 0.71 |
ENST00000543579.1
ENST00000537840.1 ENST00000343827.3 |
TCF12
|
transcription factor 12 |
| chr6_-_52860171 | 0.70 |
ENST00000370963.4
|
GSTA4
|
glutathione S-transferase alpha 4 |
| chr7_+_140378955 | 0.70 |
ENST00000473512.1
|
ADCK2
|
aarF domain containing kinase 2 |
| chr8_+_96037255 | 0.69 |
ENST00000286687.4
|
NDUFAF6
|
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 |
| chr20_+_306221 | 0.69 |
ENST00000342665.2
|
SOX12
|
SRY (sex determining region Y)-box 12 |
| chr21_+_39493560 | 0.69 |
ENST00000400477.3
ENST00000357704.4 |
DSCR8
|
Down syndrome critical region gene 8 |
| chr7_-_44122063 | 0.69 |
ENST00000335195.6
ENST00000395831.3 ENST00000414235.1 ENST00000452049.1 ENST00000242248.5 |
POLM
|
polymerase (DNA directed), mu |
| chr8_+_96037205 | 0.69 |
ENST00000396124.4
|
NDUFAF6
|
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 |
| chr7_+_64254793 | 0.69 |
ENST00000494380.1
ENST00000440155.2 ENST00000440598.1 ENST00000437743.1 |
ZNF138
|
zinc finger protein 138 |
| chr15_+_39542867 | 0.68 |
ENST00000318578.3
ENST00000561223.1 |
C15orf54
|
chromosome 15 open reading frame 54 |
| chr4_-_135122903 | 0.68 |
ENST00000421491.3
ENST00000529122.2 |
PABPC4L
|
poly(A) binding protein, cytoplasmic 4-like |
| chr18_+_47088401 | 0.68 |
ENST00000261292.4
ENST00000427224.2 ENST00000580036.1 |
LIPG
|
lipase, endothelial |
| chr9_+_77230499 | 0.68 |
ENST00000396204.2
|
RORB
|
RAR-related orphan receptor B |
| chr1_-_154832316 | 0.68 |
ENST00000361147.4
|
KCNN3
|
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 |
| chr10_+_23384435 | 0.67 |
ENST00000376510.3
|
MSRB2
|
methionine sulfoxide reductase B2 |
| chr2_-_89247338 | 0.67 |
ENST00000496168.1
|
IGKV1-5
|
immunoglobulin kappa variable 1-5 |
| chr2_+_198669365 | 0.67 |
ENST00000428675.1
|
PLCL1
|
phospholipase C-like 1 |
| chr9_-_35080013 | 0.67 |
ENST00000378643.3
|
FANCG
|
Fanconi anemia, complementation group G |
| chr17_+_73083816 | 0.67 |
ENST00000580123.1
ENST00000578847.1 |
SLC16A5
|
solute carrier family 16 (monocarboxylate transporter), member 5 |
| chr1_-_21377383 | 0.67 |
ENST00000374935.3
|
EIF4G3
|
eukaryotic translation initiation factor 4 gamma, 3 |
Network of associatons between targets according to the STRING database.
First level regulatory network of POU5F1_POU2F3
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.6 | 4.9 | GO:0070666 | positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668) |
| 1.2 | 4.7 | GO:2000691 | negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691) |
| 1.1 | 2.3 | GO:0072204 | cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) |
| 0.7 | 20.9 | GO:0072189 | ureter development(GO:0072189) |
| 0.5 | 2.2 | GO:0061624 | fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) |
| 0.5 | 3.1 | GO:0072675 | multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675) |
| 0.5 | 2.1 | GO:0035026 | leading edge cell differentiation(GO:0035026) |
| 0.4 | 1.3 | GO:0045925 | positive regulation of female receptivity(GO:0045925) |
| 0.4 | 1.2 | GO:0072709 | cellular response to sorbitol(GO:0072709) |
| 0.4 | 1.2 | GO:0021569 | rhombomere 3 development(GO:0021569) rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284) |
| 0.4 | 1.5 | GO:0060168 | positive regulation of adenosine receptor signaling pathway(GO:0060168) |
| 0.4 | 1.1 | GO:0016340 | calcium-dependent cell-matrix adhesion(GO:0016340) |
| 0.4 | 1.8 | GO:0060023 | soft palate development(GO:0060023) |
| 0.3 | 1.0 | GO:0018312 | peptidyl-serine ADP-ribosylation(GO:0018312) |
| 0.3 | 1.5 | GO:0050917 | sensory perception of umami taste(GO:0050917) |
| 0.3 | 1.8 | GO:0090245 | axis elongation involved in somitogenesis(GO:0090245) |
| 0.3 | 1.2 | GO:0009956 | radial pattern formation(GO:0009956) |
| 0.3 | 3.7 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.3 | 0.8 | GO:0014016 | neuroblast differentiation(GO:0014016) |
| 0.3 | 2.4 | GO:0014807 | regulation of somitogenesis(GO:0014807) |
| 0.3 | 0.3 | GO:0070560 | protein secretion by platelet(GO:0070560) |
| 0.3 | 0.8 | GO:1902725 | negative regulation of satellite cell differentiation(GO:1902725) |
| 0.3 | 2.0 | GO:0036484 | trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) |
| 0.2 | 0.7 | GO:0016260 | selenocysteine biosynthetic process(GO:0016260) |
| 0.2 | 0.7 | GO:1903691 | positive regulation of wound healing, spreading of epidermal cells(GO:1903691) |
| 0.2 | 0.7 | GO:0042214 | terpene metabolic process(GO:0042214) |
| 0.2 | 1.8 | GO:0021678 | third ventricle development(GO:0021678) |
| 0.2 | 0.7 | GO:0046080 | dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081) |
| 0.2 | 1.1 | GO:0018364 | peptidyl-glutamine methylation(GO:0018364) |
| 0.2 | 7.0 | GO:0061049 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.2 | 1.6 | GO:0090043 | regulation of tubulin deacetylation(GO:0090043) |
| 0.2 | 0.6 | GO:0050883 | musculoskeletal movement, spinal reflex action(GO:0050883) |
| 0.2 | 0.8 | GO:0043983 | histone H4-K12 acetylation(GO:0043983) |
| 0.2 | 0.9 | GO:1902498 | regulation of protein autoubiquitination(GO:1902498) |
| 0.2 | 0.5 | GO:0002384 | hepatic immune response(GO:0002384) |
| 0.2 | 0.5 | GO:0005988 | lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989) |
| 0.2 | 0.7 | GO:0030807 | positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123) |
| 0.2 | 0.7 | GO:0010982 | regulation of high-density lipoprotein particle clearance(GO:0010982) |
| 0.2 | 0.8 | GO:0019075 | virus maturation(GO:0019075) |
| 0.2 | 2.0 | GO:0006657 | CDP-choline pathway(GO:0006657) |
| 0.2 | 0.8 | GO:0071051 | polyadenylation-dependent snoRNA 3'-end processing(GO:0071051) |
| 0.1 | 1.8 | GO:1904936 | cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936) |
| 0.1 | 0.7 | GO:0015688 | iron chelate transport(GO:0015688) siderophore transport(GO:0015891) |
| 0.1 | 1.0 | GO:0031642 | negative regulation of myelination(GO:0031642) |
| 0.1 | 0.7 | GO:0051621 | negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470) |
| 0.1 | 0.9 | GO:0034628 | nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628) |
| 0.1 | 0.6 | GO:0046373 | arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373) |
| 0.1 | 1.4 | GO:0061088 | regulation of sequestering of zinc ion(GO:0061088) |
| 0.1 | 1.1 | GO:0007598 | blood coagulation, extrinsic pathway(GO:0007598) |
| 0.1 | 0.7 | GO:0035881 | amacrine cell differentiation(GO:0035881) |
| 0.1 | 0.9 | GO:2000795 | negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
| 0.1 | 1.8 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
| 0.1 | 2.6 | GO:2000774 | positive regulation of cellular senescence(GO:2000774) |
| 0.1 | 4.8 | GO:0009954 | proximal/distal pattern formation(GO:0009954) |
| 0.1 | 1.0 | GO:0001957 | intramembranous ossification(GO:0001957) direct ossification(GO:0036072) |
| 0.1 | 1.6 | GO:1904322 | response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322) |
| 0.1 | 0.9 | GO:0048539 | bone marrow development(GO:0048539) |
| 0.1 | 0.4 | GO:0060940 | negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387) epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940) |
| 0.1 | 0.6 | GO:0035900 | response to isolation stress(GO:0035900) |
| 0.1 | 1.7 | GO:0021514 | ventral spinal cord interneuron differentiation(GO:0021514) |
| 0.1 | 1.0 | GO:2000628 | regulation of miRNA metabolic process(GO:2000628) |
| 0.1 | 0.7 | GO:1900063 | regulation of peroxisome organization(GO:1900063) |
| 0.1 | 0.3 | GO:0001812 | positive regulation of type I hypersensitivity(GO:0001812) |
| 0.1 | 0.3 | GO:0002731 | negative regulation of dendritic cell cytokine production(GO:0002731) negative regulation of intracellular transport of viral material(GO:1901253) |
| 0.1 | 0.4 | GO:0042989 | sequestering of actin monomers(GO:0042989) |
| 0.1 | 0.5 | GO:0071596 | ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596) |
| 0.1 | 0.7 | GO:0098967 | exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967) |
| 0.1 | 0.3 | GO:0060086 | circadian temperature homeostasis(GO:0060086) positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253) |
| 0.1 | 1.5 | GO:0002115 | store-operated calcium entry(GO:0002115) |
| 0.1 | 0.4 | GO:2000342 | negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342) |
| 0.1 | 1.3 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
| 0.1 | 0.4 | GO:0007525 | somatic muscle development(GO:0007525) |
| 0.1 | 0.6 | GO:1900264 | regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264) |
| 0.1 | 0.6 | GO:0038161 | prolactin signaling pathway(GO:0038161) |
| 0.1 | 0.3 | GO:0001172 | transcription, RNA-templated(GO:0001172) |
| 0.1 | 1.5 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 0.1 | 0.3 | GO:0003289 | atrial septum primum morphogenesis(GO:0003289) N-terminal peptidyl-lysine acetylation(GO:0018076) |
| 0.1 | 0.3 | GO:0010430 | fatty acid omega-oxidation(GO:0010430) |
| 0.1 | 12.9 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
| 0.1 | 0.4 | GO:0030070 | insulin processing(GO:0030070) |
| 0.1 | 0.3 | GO:1903028 | positive regulation of opsonization(GO:1903028) |
| 0.1 | 0.7 | GO:1900122 | positive regulation of receptor binding(GO:1900122) |
| 0.1 | 0.4 | GO:0035519 | protein K29-linked ubiquitination(GO:0035519) |
| 0.1 | 0.6 | GO:0055095 | lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) |
| 0.1 | 0.2 | GO:0032764 | negative regulation of mast cell cytokine production(GO:0032764) |
| 0.1 | 2.3 | GO:0030208 | dermatan sulfate biosynthetic process(GO:0030208) |
| 0.1 | 1.1 | GO:0060056 | mammary gland involution(GO:0060056) |
| 0.1 | 0.7 | GO:0070236 | negative regulation of activation-induced cell death of T cells(GO:0070236) |
| 0.1 | 0.5 | GO:0033031 | positive regulation of neutrophil apoptotic process(GO:0033031) |
| 0.1 | 3.3 | GO:0000038 | very long-chain fatty acid metabolic process(GO:0000038) |
| 0.1 | 0.3 | GO:1900226 | negative regulation of NLRP3 inflammasome complex assembly(GO:1900226) |
| 0.1 | 0.8 | GO:0010499 | proteasomal ubiquitin-independent protein catabolic process(GO:0010499) |
| 0.1 | 1.4 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
| 0.1 | 0.7 | GO:1902746 | regulation of lens fiber cell differentiation(GO:1902746) |
| 0.1 | 0.5 | GO:0061086 | negative regulation of histone H3-K27 methylation(GO:0061086) |
| 0.1 | 0.3 | GO:0033484 | nitric oxide homeostasis(GO:0033484) |
| 0.1 | 0.6 | GO:1904885 | mesenchymal cell differentiation involved in kidney development(GO:0072161) beta-catenin destruction complex assembly(GO:1904885) mesenchymal cell differentiation involved in renal system development(GO:2001012) |
| 0.1 | 0.2 | GO:0060385 | axonogenesis involved in innervation(GO:0060385) |
| 0.1 | 0.6 | GO:0061525 | hindgut development(GO:0061525) |
| 0.1 | 0.8 | GO:0033004 | negative regulation of mast cell activation(GO:0033004) |
| 0.1 | 0.2 | GO:0044027 | hypermethylation of CpG island(GO:0044027) |
| 0.1 | 1.9 | GO:0007638 | mechanosensory behavior(GO:0007638) |
| 0.1 | 0.1 | GO:1900195 | positive regulation of oocyte maturation(GO:1900195) |
| 0.1 | 4.8 | GO:0030835 | negative regulation of actin filament depolymerization(GO:0030835) |
| 0.1 | 0.5 | GO:0031914 | negative regulation of synaptic plasticity(GO:0031914) |
| 0.1 | 0.8 | GO:0046600 | negative regulation of centriole replication(GO:0046600) |
| 0.1 | 0.1 | GO:0052314 | phytoalexin metabolic process(GO:0052314) |
| 0.1 | 0.2 | GO:0035494 | SNARE complex disassembly(GO:0035494) |
| 0.1 | 0.5 | GO:0002606 | positive regulation of dendritic cell antigen processing and presentation(GO:0002606) |
| 0.1 | 0.3 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
| 0.1 | 0.2 | GO:2000439 | CD8-positive, alpha-beta T cell extravasation(GO:0035697) negative regulation of eosinophil activation(GO:1902567) regulation of T cell extravasation(GO:2000407) positive regulation of monocyte extravasation(GO:2000439) regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000449) |
| 0.1 | 0.2 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
| 0.1 | 0.2 | GO:0046125 | thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125) |
| 0.1 | 0.2 | GO:0033385 | geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386) |
| 0.1 | 0.3 | GO:2001106 | regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106) |
| 0.1 | 2.4 | GO:0045747 | positive regulation of Notch signaling pathway(GO:0045747) |
| 0.1 | 0.5 | GO:0021615 | glossopharyngeal nerve morphogenesis(GO:0021615) |
| 0.1 | 0.2 | GO:0060278 | negative regulation of B cell differentiation(GO:0045578) regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279) |
| 0.1 | 1.1 | GO:0051601 | exocyst localization(GO:0051601) |
| 0.1 | 0.2 | GO:1902896 | terminal web assembly(GO:1902896) |
| 0.1 | 0.8 | GO:0040016 | embryonic cleavage(GO:0040016) |
| 0.1 | 0.2 | GO:2000196 | positive regulation of female gonad development(GO:2000196) regulation of progesterone secretion(GO:2000870) |
| 0.1 | 1.2 | GO:0007625 | grooming behavior(GO:0007625) |
| 0.1 | 1.7 | GO:0045898 | regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) |
| 0.1 | 3.5 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.1 | 0.1 | GO:0014859 | negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723) |
| 0.1 | 0.3 | GO:0000720 | pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) |
| 0.1 | 1.1 | GO:0097034 | mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034) |
| 0.1 | 0.2 | GO:0036510 | trimming of terminal mannose on C branch(GO:0036510) |
| 0.1 | 0.9 | GO:0032688 | negative regulation of interferon-beta production(GO:0032688) |
| 0.1 | 0.2 | GO:1902683 | regulation of receptor localization to synapse(GO:1902683) |
| 0.1 | 1.4 | GO:0019370 | leukotriene biosynthetic process(GO:0019370) |
| 0.1 | 0.5 | GO:0051388 | positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) |
| 0.1 | 0.1 | GO:0090310 | negative regulation of methylation-dependent chromatin silencing(GO:0090310) |
| 0.1 | 0.5 | GO:0042492 | gamma-delta T cell differentiation(GO:0042492) |
| 0.1 | 0.4 | GO:1904491 | protein localization to ciliary transition zone(GO:1904491) |
| 0.1 | 0.8 | GO:0033234 | negative regulation of protein sumoylation(GO:0033234) |
| 0.0 | 0.5 | GO:0030091 | protein repair(GO:0030091) |
| 0.0 | 0.6 | GO:0039530 | MDA-5 signaling pathway(GO:0039530) |
| 0.0 | 0.4 | GO:1990034 | cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034) |
| 0.0 | 0.3 | GO:0016480 | negative regulation of transcription from RNA polymerase III promoter(GO:0016480) |
| 0.0 | 0.2 | GO:0019470 | 4-hydroxyproline catabolic process(GO:0019470) |
| 0.0 | 0.6 | GO:0035372 | protein localization to microtubule(GO:0035372) |
| 0.0 | 0.3 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
| 0.0 | 0.1 | GO:0034093 | positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184) |
| 0.0 | 0.2 | GO:0060686 | esophagus smooth muscle contraction(GO:0014846) negative regulation of prostatic bud formation(GO:0060686) |
| 0.0 | 1.4 | GO:0007635 | chemosensory behavior(GO:0007635) |
| 0.0 | 0.4 | GO:0017062 | respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033) |
| 0.0 | 0.6 | GO:0052696 | flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697) |
| 0.0 | 1.5 | GO:2000811 | negative regulation of anoikis(GO:2000811) |
| 0.0 | 0.8 | GO:0045974 | miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974) |
| 0.0 | 1.6 | GO:0048305 | immunoglobulin secretion(GO:0048305) |
| 0.0 | 0.5 | GO:0006564 | L-serine biosynthetic process(GO:0006564) |
| 0.0 | 0.2 | GO:0046292 | formaldehyde metabolic process(GO:0046292) |
| 0.0 | 0.8 | GO:0033141 | positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141) |
| 0.0 | 0.3 | GO:0031666 | positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666) |
| 0.0 | 0.4 | GO:0016191 | synaptic vesicle uncoating(GO:0016191) |
| 0.0 | 0.1 | GO:0036091 | positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091) |
| 0.0 | 0.1 | GO:0035552 | oxidative single-stranded DNA demethylation(GO:0035552) |
| 0.0 | 0.4 | GO:0072307 | metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307) |
| 0.0 | 0.2 | GO:0018032 | protein amidation(GO:0018032) |
| 0.0 | 0.2 | GO:0045629 | negative regulation of T-helper 2 cell differentiation(GO:0045629) |
| 0.0 | 0.4 | GO:0014809 | regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) |
| 0.0 | 0.4 | GO:0045040 | protein import into mitochondrial outer membrane(GO:0045040) |
| 0.0 | 0.3 | GO:0098532 | histone H3-K27 trimethylation(GO:0098532) |
| 0.0 | 0.7 | GO:0016446 | somatic hypermutation of immunoglobulin genes(GO:0016446) |
| 0.0 | 0.2 | GO:0019303 | D-ribose catabolic process(GO:0019303) |
| 0.0 | 0.2 | GO:0048388 | endosomal lumen acidification(GO:0048388) |
| 0.0 | 0.2 | GO:0032074 | negative regulation of nuclease activity(GO:0032074) |
| 0.0 | 0.3 | GO:0046485 | ether lipid metabolic process(GO:0046485) |
| 0.0 | 0.4 | GO:0006069 | ethanol oxidation(GO:0006069) |
| 0.0 | 0.6 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 0.0 | 0.7 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.0 | 0.2 | GO:0072423 | response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423) regulation of apoptotic DNA fragmentation(GO:1902510) |
| 0.0 | 0.9 | GO:0042347 | negative regulation of NF-kappaB import into nucleus(GO:0042347) |
| 0.0 | 1.1 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.0 | 0.1 | GO:0048631 | regulation of skeletal muscle tissue growth(GO:0048631) |
| 0.0 | 0.3 | GO:0033623 | regulation of integrin activation(GO:0033623) |
| 0.0 | 0.3 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
| 0.0 | 0.2 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) |
| 0.0 | 0.3 | GO:0090160 | Golgi to lysosome transport(GO:0090160) |
| 0.0 | 0.1 | GO:0002740 | negative regulation of cytokine secretion involved in immune response(GO:0002740) |
| 0.0 | 0.1 | GO:0038155 | interleukin-23-mediated signaling pathway(GO:0038155) |
| 0.0 | 0.3 | GO:0021759 | globus pallidus development(GO:0021759) |
| 0.0 | 0.4 | GO:0006309 | apoptotic DNA fragmentation(GO:0006309) |
| 0.0 | 7.5 | GO:0065004 | protein-DNA complex assembly(GO:0065004) |
| 0.0 | 0.2 | GO:1902774 | late endosome to lysosome transport(GO:1902774) |
| 0.0 | 0.5 | GO:0035729 | cellular response to hepatocyte growth factor stimulus(GO:0035729) |
| 0.0 | 0.3 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
| 0.0 | 0.2 | GO:0061588 | calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591) |
| 0.0 | 0.5 | GO:0098828 | positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828) |
| 0.0 | 0.3 | GO:0019321 | pentose metabolic process(GO:0019321) |
| 0.0 | 0.3 | GO:0006707 | cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127) |
| 0.0 | 0.1 | GO:0033184 | positive regulation of histone ubiquitination(GO:0033184) |
| 0.0 | 0.6 | GO:0097369 | sodium ion import(GO:0097369) |
| 0.0 | 0.7 | GO:0072662 | protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663) |
| 0.0 | 0.2 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
| 0.0 | 0.2 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 0.0 | 0.4 | GO:1900364 | negative regulation of mRNA polyadenylation(GO:1900364) |
| 0.0 | 0.3 | GO:0043320 | natural killer cell degranulation(GO:0043320) |
| 0.0 | 0.0 | GO:0050916 | sensory perception of sweet taste(GO:0050916) |
| 0.0 | 0.3 | GO:0033483 | oxygen homeostasis(GO:0032364) gas homeostasis(GO:0033483) |
| 0.0 | 0.2 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 0.0 | 1.6 | GO:0006749 | glutathione metabolic process(GO:0006749) |
| 0.0 | 0.1 | GO:0031125 | rRNA 3'-end processing(GO:0031125) |
| 0.0 | 0.1 | GO:0071494 | cellular response to UV-C(GO:0071494) |
| 0.0 | 0.1 | GO:0009786 | regulation of asymmetric cell division(GO:0009786) |
| 0.0 | 0.1 | GO:0055064 | chloride ion homeostasis(GO:0055064) |
| 0.0 | 0.5 | GO:0045662 | negative regulation of myoblast differentiation(GO:0045662) |
| 0.0 | 0.3 | GO:0090161 | Golgi ribbon formation(GO:0090161) |
| 0.0 | 0.1 | GO:0006391 | transcription initiation from mitochondrial promoter(GO:0006391) |
| 0.0 | 0.4 | GO:0071625 | vocalization behavior(GO:0071625) |
| 0.0 | 0.4 | GO:0046856 | phosphatidylinositol dephosphorylation(GO:0046856) |
| 0.0 | 0.1 | GO:0006384 | transcription initiation from RNA polymerase III promoter(GO:0006384) |
| 0.0 | 0.2 | GO:0015939 | pantothenate metabolic process(GO:0015939) |
| 0.0 | 0.1 | GO:1903314 | nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250) |
| 0.0 | 0.1 | GO:0019860 | uracil metabolic process(GO:0019860) |
| 0.0 | 0.1 | GO:0042560 | folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560) |
| 0.0 | 0.1 | GO:0048023 | positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378) |
| 0.0 | 0.5 | GO:0034587 | piRNA metabolic process(GO:0034587) |
| 0.0 | 0.9 | GO:0015721 | bile acid and bile salt transport(GO:0015721) |
| 0.0 | 0.2 | GO:1903800 | positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800) |
| 0.0 | 0.1 | GO:0051013 | microtubule severing(GO:0051013) |
| 0.0 | 0.3 | GO:0060155 | platelet dense granule organization(GO:0060155) |
| 0.0 | 0.1 | GO:2000435 | regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435) |
| 0.0 | 3.1 | GO:0031424 | keratinization(GO:0031424) |
| 0.0 | 0.1 | GO:0060762 | regulation of branching involved in mammary gland duct morphogenesis(GO:0060762) |
| 0.0 | 0.1 | GO:0046909 | intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445) |
| 0.0 | 0.2 | GO:0033299 | secretion of lysosomal enzymes(GO:0033299) |
| 0.0 | 0.8 | GO:0046039 | GTP metabolic process(GO:0046039) |
| 0.0 | 1.3 | GO:0016239 | positive regulation of macroautophagy(GO:0016239) |
| 0.0 | 0.1 | GO:0060741 | prostate gland stromal morphogenesis(GO:0060741) |
| 0.0 | 0.2 | GO:0031284 | positive regulation of guanylate cyclase activity(GO:0031284) |
| 0.0 | 0.3 | GO:0033169 | histone H3-K9 demethylation(GO:0033169) |
| 0.0 | 2.0 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
| 0.0 | 0.1 | GO:0015862 | uridine transport(GO:0015862) |
| 0.0 | 0.1 | GO:0014877 | response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
| 0.0 | 0.2 | GO:0043651 | linoleic acid metabolic process(GO:0043651) |
| 0.0 | 1.4 | GO:0030032 | lamellipodium assembly(GO:0030032) |
| 0.0 | 0.3 | GO:0032516 | positive regulation of phosphoprotein phosphatase activity(GO:0032516) |
| 0.0 | 0.2 | GO:0008343 | adult feeding behavior(GO:0008343) |
| 0.0 | 0.7 | GO:0014911 | positive regulation of smooth muscle cell migration(GO:0014911) |
| 0.0 | 0.2 | GO:0006089 | lactate metabolic process(GO:0006089) |
| 0.0 | 0.8 | GO:1901661 | quinone metabolic process(GO:1901661) |
| 0.0 | 0.6 | GO:0045672 | positive regulation of osteoclast differentiation(GO:0045672) |
| 0.0 | 0.1 | GO:0030187 | melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187) |
| 0.0 | 0.7 | GO:0036297 | interstrand cross-link repair(GO:0036297) |
| 0.0 | 0.3 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
| 0.0 | 0.0 | GO:0046010 | positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010) |
| 0.0 | 0.3 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
| 0.0 | 0.5 | GO:0009083 | branched-chain amino acid catabolic process(GO:0009083) |
| 0.0 | 0.1 | GO:0038031 | non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031) |
| 0.0 | 1.4 | GO:0097031 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
| 0.0 | 0.2 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 0.0 | 0.3 | GO:0006012 | galactose metabolic process(GO:0006012) |
| 0.0 | 0.7 | GO:0030866 | cortical actin cytoskeleton organization(GO:0030866) |
| 0.0 | 0.1 | GO:0042357 | thiamine diphosphate metabolic process(GO:0042357) |
| 0.0 | 0.1 | GO:0010387 | COP9 signalosome assembly(GO:0010387) |
| 0.0 | 0.1 | GO:0021815 | modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration(GO:0021815) nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240) |
| 0.0 | 1.0 | GO:0005978 | glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250) |
| 0.0 | 1.6 | GO:0002377 | immunoglobulin production(GO:0002377) |
| 0.0 | 0.1 | GO:0030382 | sperm mitochondrion organization(GO:0030382) |
| 0.0 | 0.1 | GO:0070966 | nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) |
| 0.0 | 0.1 | GO:0050966 | detection of mechanical stimulus involved in sensory perception of pain(GO:0050966) |
| 0.0 | 0.2 | GO:0033147 | negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147) |
| 0.0 | 0.1 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 0.0 | 0.1 | GO:0045872 | positive regulation of rhodopsin gene expression(GO:0045872) |
| 0.0 | 0.1 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
| 0.0 | 0.2 | GO:0015871 | choline transport(GO:0015871) |
| 0.0 | 0.1 | GO:1902969 | mitotic DNA replication(GO:1902969) |
| 0.0 | 0.2 | GO:1902001 | fatty acid transmembrane transport(GO:1902001) |
| 0.0 | 0.0 | GO:0035992 | tendon cell differentiation(GO:0035990) tendon formation(GO:0035992) |
| 0.0 | 0.4 | GO:0035428 | hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659) |
| 0.0 | 0.6 | GO:0006270 | DNA replication initiation(GO:0006270) |
| 0.0 | 0.1 | GO:0032463 | negative regulation of protein homooligomerization(GO:0032463) |
| 0.0 | 0.1 | GO:2000271 | positive regulation of fibroblast apoptotic process(GO:2000271) |
| 0.0 | 0.1 | GO:0002399 | MHC protein complex assembly(GO:0002396) MHC class II protein complex assembly(GO:0002399) |
| 0.0 | 0.2 | GO:0030277 | maintenance of gastrointestinal epithelium(GO:0030277) |
| 0.0 | 0.1 | GO:0019375 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.0 | 0.3 | GO:0060325 | face morphogenesis(GO:0060325) |
| 0.0 | 0.5 | GO:0030513 | positive regulation of BMP signaling pathway(GO:0030513) |
| 0.0 | 0.0 | GO:0009213 | pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213) |
| 0.0 | 0.1 | GO:0009629 | response to gravity(GO:0009629) |
| 0.0 | 0.1 | GO:0016255 | attachment of GPI anchor to protein(GO:0016255) |
| 0.0 | 0.1 | GO:0042904 | 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905) |
| 0.0 | 0.8 | GO:0006968 | cellular defense response(GO:0006968) |
| 0.0 | 0.5 | GO:0014047 | glutamate secretion(GO:0014047) |
| 0.0 | 0.3 | GO:1902186 | regulation of viral release from host cell(GO:1902186) |
| 0.0 | 0.2 | GO:0001682 | tRNA 5'-leader removal(GO:0001682) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 4.9 | GO:0034666 | integrin alpha2-beta1 complex(GO:0034666) |
| 0.4 | 3.7 | GO:0071953 | elastic fiber(GO:0071953) |
| 0.3 | 0.9 | GO:0071745 | IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751) |
| 0.3 | 0.3 | GO:0034680 | integrin alpha10-beta1 complex(GO:0034680) |
| 0.3 | 0.8 | GO:0009330 | DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330) |
| 0.2 | 2.1 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
| 0.2 | 0.6 | GO:0097598 | sperm cytoplasmic droplet(GO:0097598) |
| 0.2 | 0.7 | GO:1990796 | photoreceptor cell terminal bouton(GO:1990796) |
| 0.1 | 0.5 | GO:0005896 | interleukin-6 receptor complex(GO:0005896) |
| 0.1 | 0.4 | GO:0031084 | BLOC-2 complex(GO:0031084) |
| 0.1 | 1.7 | GO:0061700 | GATOR2 complex(GO:0061700) |
| 0.1 | 0.4 | GO:0032002 | interleukin-28 receptor complex(GO:0032002) |
| 0.1 | 0.5 | GO:0016533 | cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533) |
| 0.1 | 0.8 | GO:0035867 | alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867) |
| 0.1 | 0.9 | GO:0098559 | cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560) |
| 0.1 | 4.1 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
| 0.1 | 1.2 | GO:0070938 | contractile ring(GO:0070938) |
| 0.1 | 1.2 | GO:0098647 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 0.1 | 0.6 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
| 0.1 | 0.5 | GO:0005947 | mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) |
| 0.1 | 0.9 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.1 | 0.7 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
| 0.1 | 0.9 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.1 | 0.8 | GO:0035749 | myelin sheath adaxonal region(GO:0035749) |
| 0.1 | 0.6 | GO:0071546 | pi-body(GO:0071546) |
| 0.1 | 3.9 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.1 | 0.2 | GO:0043511 | inhibin complex(GO:0043511) inhibin A complex(GO:0043512) |
| 0.1 | 0.2 | GO:0043293 | apoptosome(GO:0043293) |
| 0.1 | 0.8 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.1 | 0.9 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.1 | 0.8 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
| 0.1 | 0.7 | GO:0032039 | integrator complex(GO:0032039) |
| 0.0 | 0.3 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
| 0.0 | 0.2 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
| 0.0 | 0.3 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.0 | 0.3 | GO:0031415 | NatA complex(GO:0031415) |
| 0.0 | 0.2 | GO:0098536 | deuterosome(GO:0098536) |
| 0.0 | 0.2 | GO:1990357 | terminal web(GO:1990357) |
| 0.0 | 0.3 | GO:0000110 | nucleotide-excision repair factor 1 complex(GO:0000110) |
| 0.0 | 0.3 | GO:0097361 | CIA complex(GO:0097361) |
| 0.0 | 0.8 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.0 | 0.3 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
| 0.0 | 2.5 | GO:0000786 | nucleosome(GO:0000786) |
| 0.0 | 0.9 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.0 | 0.2 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
| 0.0 | 0.1 | GO:0000811 | GINS complex(GO:0000811) |
| 0.0 | 2.1 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.0 | 0.4 | GO:0098799 | outer mitochondrial membrane protein complex(GO:0098799) |
| 0.0 | 0.5 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.0 | 1.1 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.0 | 4.8 | GO:0032993 | protein-DNA complex(GO:0032993) |
| 0.0 | 2.1 | GO:0002102 | podosome(GO:0002102) |
| 0.0 | 2.8 | GO:0035577 | azurophil granule membrane(GO:0035577) |
| 0.0 | 2.4 | GO:0045095 | keratin filament(GO:0045095) |
| 0.0 | 0.2 | GO:0032437 | cuticular plate(GO:0032437) |
| 0.0 | 6.3 | GO:0030018 | Z disc(GO:0030018) |
| 0.0 | 0.1 | GO:0072536 | interleukin-23 receptor complex(GO:0072536) |
| 0.0 | 0.2 | GO:0033263 | CORVET complex(GO:0033263) |
| 0.0 | 1.2 | GO:1902555 | endoribonuclease complex(GO:1902555) |
| 0.0 | 0.3 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 0.0 | 0.4 | GO:0033162 | melanosome membrane(GO:0033162) chitosome(GO:0045009) |
| 0.0 | 0.9 | GO:0000145 | exocyst(GO:0000145) |
| 0.0 | 1.2 | GO:0030315 | T-tubule(GO:0030315) |
| 0.0 | 0.6 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.0 | 0.6 | GO:0005686 | U2 snRNP(GO:0005686) |
| 0.0 | 0.9 | GO:0042629 | mast cell granule(GO:0042629) |
| 0.0 | 0.2 | GO:0016272 | prefoldin complex(GO:0016272) |
| 0.0 | 0.1 | GO:0098574 | cytoplasmic side of lysosomal membrane(GO:0098574) |
| 0.0 | 0.1 | GO:0042585 | germinal vesicle(GO:0042585) |
| 0.0 | 0.3 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.0 | 2.6 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.0 | 0.3 | GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex(GO:0031464) |
| 0.0 | 3.3 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.0 | 0.3 | GO:0033093 | Weibel-Palade body(GO:0033093) |
| 0.0 | 0.1 | GO:0042765 | GPI-anchor transamidase complex(GO:0042765) |
| 0.0 | 0.4 | GO:0036038 | MKS complex(GO:0036038) |
| 0.0 | 0.1 | GO:0097179 | protease inhibitor complex(GO:0097179) |
| 0.0 | 0.3 | GO:0030904 | retromer complex(GO:0030904) |
| 0.0 | 0.1 | GO:0036398 | TCR signalosome(GO:0036398) |
| 0.0 | 0.2 | GO:0005664 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
| 0.0 | 1.8 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.0 | 0.4 | GO:0031528 | microvillus membrane(GO:0031528) |
| 0.0 | 0.2 | GO:0031045 | dense core granule(GO:0031045) |
| 0.0 | 0.5 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.0 | 0.4 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 0.0 | 2.2 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
| 0.0 | 0.2 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.0 | 1.3 | GO:0000123 | histone acetyltransferase complex(GO:0000123) |
| 0.0 | 0.1 | GO:0030915 | Smc5-Smc6 complex(GO:0030915) |
| 0.0 | 0.1 | GO:0097169 | AIM2 inflammasome complex(GO:0097169) |
| 0.0 | 0.1 | GO:0097149 | centralspindlin complex(GO:0097149) |
| 0.0 | 0.1 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
| 0.0 | 0.4 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
| 0.0 | 0.1 | GO:0036449 | microtubule minus-end(GO:0036449) |
| 0.0 | 0.4 | GO:0044298 | neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298) |
| 0.0 | 0.0 | GO:1990742 | microvesicle(GO:1990742) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 4.6 | GO:0043208 | glycosphingolipid binding(GO:0043208) |
| 0.5 | 1.5 | GO:0052642 | lysophosphatidic acid phosphatase activity(GO:0052642) |
| 0.5 | 1.5 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
| 0.4 | 2.2 | GO:0018479 | benzaldehyde dehydrogenase (NAD+) activity(GO:0018479) |
| 0.4 | 2.0 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
| 0.4 | 1.1 | GO:0004464 | leukotriene-C4 synthase activity(GO:0004464) |
| 0.3 | 1.0 | GO:1990404 | protein ADP-ribosylase activity(GO:1990404) |
| 0.3 | 3.8 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.2 | 0.7 | GO:0004756 | selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781) |
| 0.2 | 1.2 | GO:0047757 | chondroitin-glucuronate 5-epimerase activity(GO:0047757) |
| 0.2 | 0.7 | GO:0004170 | dUTP diphosphatase activity(GO:0004170) |
| 0.2 | 3.1 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.2 | 6.4 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.2 | 0.8 | GO:0003990 | acetylcholinesterase activity(GO:0003990) |
| 0.2 | 1.0 | GO:0032296 | ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) |
| 0.2 | 3.1 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
| 0.2 | 2.7 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
| 0.2 | 2.1 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
| 0.2 | 0.5 | GO:0005176 | ErbB-2 class receptor binding(GO:0005176) |
| 0.1 | 0.6 | GO:0051800 | phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800) |
| 0.1 | 0.7 | GO:0060961 | phospholipase D inhibitor activity(GO:0060961) |
| 0.1 | 0.9 | GO:0000309 | nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) |
| 0.1 | 0.6 | GO:0046556 | alpha-L-arabinofuranosidase activity(GO:0046556) |
| 0.1 | 1.4 | GO:0034594 | inositol-polyphosphate 5-phosphatase activity(GO:0004445) phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485) phosphatidylinositol trisphosphate phosphatase activity(GO:0034594) |
| 0.1 | 0.7 | GO:0016286 | small conductance calcium-activated potassium channel activity(GO:0016286) |
| 0.1 | 1.6 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
| 0.1 | 0.5 | GO:0004461 | lactose synthase activity(GO:0004461) |
| 0.1 | 1.1 | GO:0043237 | laminin-1 binding(GO:0043237) |
| 0.1 | 1.1 | GO:0003960 | NADPH:quinone reductase activity(GO:0003960) |
| 0.1 | 0.5 | GO:0043812 | phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) |
| 0.1 | 0.7 | GO:0033743 | peptide-methionine (R)-S-oxide reductase activity(GO:0033743) |
| 0.1 | 0.6 | GO:0004925 | prolactin receptor activity(GO:0004925) |
| 0.1 | 2.6 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.1 | 1.7 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 0.1 | 0.3 | GO:0010309 | acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309) |
| 0.1 | 0.3 | GO:0004157 | dihydropyrimidinase activity(GO:0004157) |
| 0.1 | 0.3 | GO:0033858 | N-acetylgalactosamine kinase activity(GO:0033858) |
| 0.1 | 0.8 | GO:0015220 | choline transmembrane transporter activity(GO:0015220) |
| 0.1 | 1.7 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
| 0.1 | 0.3 | GO:0003968 | RNA-directed RNA polymerase activity(GO:0003968) |
| 0.1 | 0.5 | GO:0004647 | phosphoserine phosphatase activity(GO:0004647) |
| 0.1 | 1.5 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
| 0.1 | 2.4 | GO:0008527 | taste receptor activity(GO:0008527) |
| 0.1 | 0.8 | GO:0043426 | MRF binding(GO:0043426) |
| 0.1 | 0.6 | GO:0001591 | dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591) |
| 0.1 | 0.9 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.1 | 1.3 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) |
| 0.1 | 0.8 | GO:0003917 | DNA topoisomerase type I activity(GO:0003917) |
| 0.1 | 0.8 | GO:0070324 | thyroid hormone binding(GO:0070324) |
| 0.1 | 0.2 | GO:0004137 | deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797) |
| 0.1 | 1.1 | GO:0003836 | beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836) |
| 0.1 | 4.1 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.1 | 1.7 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.1 | 0.5 | GO:0004522 | ribonuclease A activity(GO:0004522) |
| 0.1 | 1.8 | GO:0071837 | HMG box domain binding(GO:0071837) |
| 0.1 | 0.4 | GO:0050544 | arachidonic acid binding(GO:0050544) |
| 0.1 | 0.5 | GO:0070679 | inositol 1,4,5 trisphosphate binding(GO:0070679) |
| 0.1 | 0.2 | GO:0000384 | first spliceosomal transesterification activity(GO:0000384) |
| 0.1 | 0.4 | GO:0047179 | platelet-activating factor acetyltransferase activity(GO:0047179) |
| 0.1 | 0.6 | GO:0033170 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 0.1 | 0.6 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
| 0.1 | 0.2 | GO:0017129 | triglyceride binding(GO:0017129) |
| 0.1 | 13.2 | GO:0003823 | antigen binding(GO:0003823) |
| 0.1 | 0.3 | GO:0004031 | aldehyde oxidase activity(GO:0004031) |
| 0.1 | 0.6 | GO:0001225 | RNA polymerase II transcription coactivator binding(GO:0001225) |
| 0.1 | 0.6 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
| 0.1 | 0.8 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.1 | 0.2 | GO:0005483 | soluble NSF attachment protein activity(GO:0005483) |
| 0.1 | 0.2 | GO:0004517 | nitric-oxide synthase activity(GO:0004517) |
| 0.1 | 0.6 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
| 0.1 | 0.4 | GO:0070892 | lipoteichoic acid receptor activity(GO:0070892) |
| 0.1 | 29.0 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
| 0.1 | 1.4 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
| 0.1 | 0.5 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
| 0.1 | 1.8 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
| 0.1 | 0.2 | GO:0004657 | proline dehydrogenase activity(GO:0004657) |
| 0.1 | 0.2 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.1 | 0.3 | GO:0019763 | immunoglobulin receptor activity(GO:0019763) |
| 0.1 | 0.2 | GO:0016812 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812) |
| 0.1 | 0.7 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.1 | 0.4 | GO:0034597 | phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) |
| 0.1 | 0.2 | GO:0031727 | CCR2 chemokine receptor binding(GO:0031727) |
| 0.1 | 0.3 | GO:0005499 | vitamin D binding(GO:0005499) |
| 0.0 | 1.1 | GO:0015125 | bile acid transmembrane transporter activity(GO:0015125) |
| 0.0 | 0.8 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213) |
| 0.0 | 0.8 | GO:0005132 | type I interferon receptor binding(GO:0005132) |
| 0.0 | 0.7 | GO:0008970 | phosphatidylcholine 1-acylhydrolase activity(GO:0008970) |
| 0.0 | 0.2 | GO:0017099 | very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099) |
| 0.0 | 0.9 | GO:0005549 | odorant binding(GO:0005549) |
| 0.0 | 1.0 | GO:0008656 | cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656) |
| 0.0 | 0.2 | GO:0017159 | pantetheine hydrolase activity(GO:0017159) |
| 0.0 | 1.7 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.0 | 1.9 | GO:0051393 | alpha-actinin binding(GO:0051393) |
| 0.0 | 0.3 | GO:0098639 | collagen binding involved in cell-matrix adhesion(GO:0098639) |
| 0.0 | 0.3 | GO:0016714 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714) |
| 0.0 | 0.3 | GO:0001594 | trace-amine receptor activity(GO:0001594) |
| 0.0 | 0.1 | GO:0035514 | DNA demethylase activity(GO:0035514) |
| 0.0 | 0.4 | GO:0004920 | interleukin-10 receptor activity(GO:0004920) |
| 0.0 | 0.1 | GO:0047275 | glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275) |
| 0.0 | 0.2 | GO:0004504 | peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598) |
| 0.0 | 0.3 | GO:1990599 | 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599) |
| 0.0 | 0.2 | GO:0003998 | acylphosphatase activity(GO:0003998) |
| 0.0 | 0.2 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
| 0.0 | 0.4 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.0 | 0.9 | GO:0000339 | RNA cap binding(GO:0000339) |
| 0.0 | 0.4 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
| 0.0 | 0.2 | GO:0004161 | dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337) |
| 0.0 | 0.5 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.0 | 0.5 | GO:0055056 | D-glucose transmembrane transporter activity(GO:0055056) |
| 0.0 | 0.1 | GO:0004809 | tRNA (guanine-N2-)-methyltransferase activity(GO:0004809) |
| 0.0 | 0.1 | GO:0019166 | trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166) |
| 0.0 | 0.3 | GO:0008379 | RNA polymerase III regulatory region DNA binding(GO:0001016) thioredoxin peroxidase activity(GO:0008379) |
| 0.0 | 0.2 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
| 0.0 | 0.7 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
| 0.0 | 1.5 | GO:0008028 | monocarboxylic acid transmembrane transporter activity(GO:0008028) |
| 0.0 | 0.7 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.0 | 0.2 | GO:0004771 | sterol esterase activity(GO:0004771) |
| 0.0 | 0.1 | GO:0042019 | interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020) |
| 0.0 | 0.5 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.0 | 0.5 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
| 0.0 | 0.2 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 0.0 | 0.1 | GO:0030272 | 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272) |
| 0.0 | 0.4 | GO:0048156 | tau protein binding(GO:0048156) |
| 0.0 | 0.5 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.0 | 0.5 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.0 | 0.2 | GO:0004972 | NMDA glutamate receptor activity(GO:0004972) |
| 0.0 | 4.1 | GO:0005178 | integrin binding(GO:0005178) |
| 0.0 | 1.1 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.0 | 0.3 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 0.0 | 1.2 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.0 | 0.1 | GO:0004118 | cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) |
| 0.0 | 0.3 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
| 0.0 | 0.1 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 0.0 | 0.1 | GO:0099580 | ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580) |
| 0.0 | 0.1 | GO:0030984 | kininogen binding(GO:0030984) |
| 0.0 | 0.2 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
| 0.0 | 0.2 | GO:0004064 | arylesterase activity(GO:0004064) |
| 0.0 | 0.1 | GO:0003923 | GPI-anchor transamidase activity(GO:0003923) |
| 0.0 | 1.2 | GO:0018024 | histone-lysine N-methyltransferase activity(GO:0018024) |
| 0.0 | 0.1 | GO:1990829 | C-rich single-stranded DNA binding(GO:1990829) |
| 0.0 | 1.8 | GO:0001158 | enhancer sequence-specific DNA binding(GO:0001158) |
| 0.0 | 0.3 | GO:0001222 | transcription corepressor binding(GO:0001222) |
| 0.0 | 0.9 | GO:0000175 | 3'-5'-exoribonuclease activity(GO:0000175) |
| 0.0 | 0.7 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 0.0 | 0.7 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.0 | 0.2 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
| 0.0 | 0.2 | GO:0050700 | CARD domain binding(GO:0050700) |
| 0.0 | 0.6 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.0 | 0.1 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 0.0 | 0.6 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.0 | 0.3 | GO:0036374 | glutathione hydrolase activity(GO:0036374) |
| 0.0 | 0.1 | GO:0035663 | Toll-like receptor 2 binding(GO:0035663) |
| 0.0 | 0.3 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.0 | 0.1 | GO:0097100 | supercoiled DNA binding(GO:0097100) |
| 0.0 | 0.1 | GO:0004126 | cytidine deaminase activity(GO:0004126) |
| 0.0 | 0.2 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
| 0.0 | 0.2 | GO:0008301 | DNA binding, bending(GO:0008301) |
| 0.0 | 0.4 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.0 | 0.5 | GO:0042287 | MHC protein binding(GO:0042287) |
| 0.0 | 0.7 | GO:0008276 | protein methyltransferase activity(GO:0008276) |
| 0.0 | 0.2 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.0 | 1.7 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 0.2 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 0.0 | 0.2 | GO:0005537 | mannose binding(GO:0005537) |
| 0.0 | 0.1 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.0 | 1.3 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
| 0.0 | 0.0 | GO:0031731 | CCR6 chemokine receptor binding(GO:0031731) |
| 0.0 | 0.1 | GO:0008142 | oxysterol binding(GO:0008142) |
| 0.0 | 0.1 | GO:0000213 | tRNA-intron endonuclease activity(GO:0000213) |
| 0.0 | 0.6 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.0 | 0.1 | GO:0008494 | translation activator activity(GO:0008494) |
| 0.0 | 0.4 | GO:0008143 | poly(A) binding(GO:0008143) |
| 0.0 | 0.1 | GO:0005502 | 11-cis retinal binding(GO:0005502) |
| 0.0 | 0.2 | GO:0004526 | ribonuclease P activity(GO:0004526) |
| 0.0 | 0.1 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
| 0.0 | 0.8 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.0 | 0.1 | GO:0045159 | myosin II binding(GO:0045159) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 24.1 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.1 | 0.7 | ST G ALPHA S PATHWAY | G alpha s Pathway |
| 0.1 | 7.5 | PID P38 ALPHA BETA PATHWAY | Regulation of p38-alpha and p38-beta |
| 0.1 | 2.1 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.1 | 1.6 | PID S1P S1P4 PATHWAY | S1P4 pathway |
| 0.1 | 0.9 | ST PAC1 RECEPTOR PATHWAY | PAC1 Receptor Pathway |
| 0.0 | 1.8 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.0 | 2.2 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.0 | 0.7 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.0 | 0.5 | ST STAT3 PATHWAY | STAT3 Pathway |
| 0.0 | 1.0 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.0 | 1.3 | PID ER NONGENOMIC PATHWAY | Plasma membrane estrogen receptor signaling |
| 0.0 | 1.5 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.0 | 4.5 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.0 | 0.9 | PID NFKAPPAB ATYPICAL PATHWAY | Atypical NF-kappaB pathway |
| 0.0 | 0.7 | PID PI3K PLC TRK PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
| 0.0 | 1.7 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.0 | 0.8 | PID MAPK TRK PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.0 | 0.8 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
| 0.0 | 1.2 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.0 | 1.0 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.0 | 0.1 | PID IL23 PATHWAY | IL23-mediated signaling events |
| 0.0 | 1.0 | PID FCER1 PATHWAY | Fc-epsilon receptor I signaling in mast cells |
| 0.0 | 0.8 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.0 | 1.2 | PID CD8 TCR PATHWAY | TCR signaling in naïve CD8+ T cells |
| 0.0 | 0.2 | PID IL12 2PATHWAY | IL12-mediated signaling events |
| 0.0 | 0.2 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.0 | 0.4 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.0 | 1.4 | PID E2F PATHWAY | E2F transcription factor network |
| 0.0 | 0.9 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.0 | 3.2 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 0.1 | PID LYMPH ANGIOGENESIS PATHWAY | VEGFR3 signaling in lymphatic endothelium |
| 0.0 | 0.6 | PID PTP1B PATHWAY | Signaling events mediated by PTP1B |
| 0.0 | 0.3 | PID ENDOTHELIN PATHWAY | Endothelins |
| 0.0 | 0.3 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.0 | 0.2 | PID BARD1 PATHWAY | BARD1 signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 4.9 | REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
| 0.2 | 2.9 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
| 0.1 | 2.1 | REACTOME GAP JUNCTION DEGRADATION | Genes involved in Gap junction degradation |
| 0.1 | 1.3 | REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS | Genes involved in Elevation of cytosolic Ca2+ levels |
| 0.1 | 1.6 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
| 0.1 | 5.0 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.1 | 1.6 | REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY | Genes involved in Adenylate cyclase inhibitory pathway |
| 0.1 | 2.3 | REACTOME DCC MEDIATED ATTRACTIVE SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.1 | 1.7 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.1 | 2.4 | REACTOME SYNTHESIS OF PC | Genes involved in Synthesis of PC |
| 0.1 | 1.7 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.1 | 0.8 | REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE | Genes involved in mRNA Decay by 3' to 5' Exoribonuclease |
| 0.1 | 1.9 | REACTOME REGULATORY RNA PATHWAYS | Genes involved in Regulatory RNA pathways |
| 0.0 | 0.6 | REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
| 0.0 | 1.1 | REACTOME RNA POL III TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
| 0.0 | 0.6 | REACTOME POL SWITCHING | Genes involved in Polymerase switching |
| 0.0 | 2.4 | REACTOME RNA POL I PROMOTER OPENING | Genes involved in RNA Polymerase I Promoter Opening |
| 0.0 | 1.1 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.0 | 0.2 | REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION | Genes involved in Unblocking of NMDA receptor, glutamate binding and activation |
| 0.0 | 0.8 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.0 | 0.3 | REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.0 | 1.6 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.0 | 1.1 | REACTOME FANCONI ANEMIA PATHWAY | Genes involved in Fanconi Anemia pathway |
| 0.0 | 0.6 | REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON | Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon |
| 0.0 | 0.8 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.0 | 1.1 | REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE | Genes involved in Formation of Fibrin Clot (Clotting Cascade) |
| 0.0 | 1.4 | REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
| 0.0 | 0.5 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.0 | 0.7 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.0 | 2.9 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.0 | 0.5 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 0.0 | 0.4 | REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS | Genes involved in p130Cas linkage to MAPK signaling for integrins |
| 0.0 | 0.5 | REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Dopamine Neurotransmitter Release Cycle |
| 0.0 | 0.5 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.0 | 0.6 | REACTOME PROLACTIN RECEPTOR SIGNALING | Genes involved in Prolactin receptor signaling |
| 0.0 | 0.6 | REACTOME REGULATION OF IFNA SIGNALING | Genes involved in Regulation of IFNA signaling |
| 0.0 | 1.2 | REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM | Genes involved in Chondroitin sulfate/dermatan sulfate metabolism |
| 0.0 | 1.0 | REACTOME RAP1 SIGNALLING | Genes involved in Rap1 signalling |
| 0.0 | 0.5 | REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 | Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 |
| 0.0 | 0.5 | REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.0 | 0.2 | REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |
| 0.0 | 0.8 | REACTOME PYRIMIDINE METABOLISM | Genes involved in Pyrimidine metabolism |
| 0.0 | 0.5 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.0 | 0.4 | REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE | Genes involved in NGF signalling via TRKA from the plasma membrane |
| 0.0 | 0.9 | REACTOME AMINE LIGAND BINDING RECEPTORS | Genes involved in Amine ligand-binding receptors |
| 0.0 | 0.5 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.0 | 0.4 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.0 | 0.4 | REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT | Genes involved in ABC-family proteins mediated transport |
| 0.0 | 0.3 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.0 | 0.1 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
| 0.0 | 0.6 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.0 | 0.2 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.0 | 0.7 | REACTOME SEMA4D IN SEMAPHORIN SIGNALING | Genes involved in Sema4D in semaphorin signaling |
| 0.0 | 0.3 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 0.0 | 0.2 | REACTOME GLYCOPROTEIN HORMONES | Genes involved in Glycoprotein hormones |
| 0.0 | 0.5 | REACTOME LYSOSOME VESICLE BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
| 0.0 | 0.3 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.0 | 0.3 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.0 | 0.2 | REACTOME CALNEXIN CALRETICULIN CYCLE | Genes involved in Calnexin/calreticulin cycle |
| 0.0 | 0.5 | REACTOME TRAFFICKING OF AMPA RECEPTORS | Genes involved in Trafficking of AMPA receptors |
| 0.0 | 1.1 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |