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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for RARA

Z-value: 0.74

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Transcription factors associated with RARA

Gene Symbol Gene ID Gene Info
RARA
ENSG00000131759.13 retinoic acid receptor alpha

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RARAhg19_v2_chr17_+_38498594_38498661-0.106.3e-01Click!

Activity profile of RARA motif

Sorted Z-values of RARA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_37654693 2.09 ENST00000412232.2
GPR124
G protein-coupled receptor 124
chr10_-_131762105 1.83 ENST00000368648.3
ENST00000355311.5
EBF3
early B-cell factor 3
chr1_+_185703513 1.53 ENST00000271588.4
ENST00000367492.2
HMCN1
hemicentin 1
chr7_+_150211918 1.48 ENST00000313543.4
GIMAP7
GTPase, IMAP family member 7
chr14_-_91526462 1.42 ENST00000536315.2
RPS6KA5
ribosomal protein S6 kinase, 90kDa, polypeptide 5
chr2_+_189157498 1.40 ENST00000359135.3
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr1_+_78511586 1.20 ENST00000370759.3
GIPC2
GIPC PDZ domain containing family, member 2
chr1_+_25870070 1.12 ENST00000374338.4
LDLRAP1
low density lipoprotein receptor adaptor protein 1
chr17_-_34122596 1.12 ENST00000250144.8
MMP28
matrix metallopeptidase 28
chr4_-_90758118 1.10 ENST00000420646.2
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr16_+_4838412 0.97 ENST00000589327.1
SMIM22
small integral membrane protein 22
chr12_-_110011288 0.93 ENST00000540016.1
ENST00000266839.5
MMAB
methylmalonic aciduria (cobalamin deficiency) cblB type
chr2_+_189157536 0.93 ENST00000409580.1
ENST00000409637.3
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr4_-_107237374 0.89 ENST00000361687.4
ENST00000507696.1
ENST00000394708.2
ENST00000509532.1
TBCK
TBC1 domain containing kinase
chr5_-_31532160 0.89 ENST00000511367.2
ENST00000513349.1
DROSHA
drosha, ribonuclease type III
chr11_-_2906979 0.89 ENST00000380725.1
ENST00000313407.6
ENST00000430149.2
ENST00000440480.2
ENST00000414822.3
CDKN1C
cyclin-dependent kinase inhibitor 1C (p57, Kip2)
chr4_-_107237340 0.88 ENST00000394706.3
TBCK
TBC1 domain containing kinase
chr7_+_155090271 0.86 ENST00000476756.1
INSIG1
insulin induced gene 1
chr5_-_43313574 0.84 ENST00000325110.6
ENST00000433297.2
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr3_-_101232019 0.84 ENST00000394095.2
ENST00000394091.1
ENST00000394094.2
ENST00000358203.3
ENST00000348610.3
ENST00000314261.7
SENP7
SUMO1/sentrin specific peptidase 7
chr7_-_21985656 0.80 ENST00000406877.3
CDCA7L
cell division cycle associated 7-like
chr19_-_12992244 0.79 ENST00000538460.1
DNASE2
deoxyribonuclease II, lysosomal
chr5_-_135290705 0.78 ENST00000274507.1
LECT2
leukocyte cell-derived chemotaxin 2
chr8_-_29120580 0.78 ENST00000524189.1
KIF13B
kinesin family member 13B
chr11_-_71159458 0.77 ENST00000355527.3
DHCR7
7-dehydrocholesterol reductase
chr8_+_70404996 0.75 ENST00000402687.4
ENST00000419716.3
SULF1
sulfatase 1
chr17_+_78075361 0.75 ENST00000577106.1
ENST00000390015.3
GAA
glucosidase, alpha; acid
chr15_-_34659349 0.73 ENST00000314891.6
LPCAT4
lysophosphatidylcholine acyltransferase 4
chr11_-_71159380 0.73 ENST00000525346.1
ENST00000531364.1
ENST00000529990.1
ENST00000527316.1
ENST00000407721.2
DHCR7
7-dehydrocholesterol reductase
chr12_+_110011571 0.73 ENST00000539696.1
ENST00000228510.3
ENST00000392727.3
MVK
mevalonate kinase
chr22_+_25465786 0.72 ENST00000401395.1
KIAA1671
KIAA1671
chr11_-_62997124 0.70 ENST00000306494.6
SLC22A25
solute carrier family 22, member 25
chr6_-_110500905 0.69 ENST00000392587.2
WASF1
WAS protein family, member 1
chr14_-_75536182 0.66 ENST00000555463.1
ACYP1
acylphosphatase 1, erythrocyte (common) type
chr6_+_53659746 0.66 ENST00000370888.1
LRRC1
leucine rich repeat containing 1
chr13_+_103451399 0.65 ENST00000257336.1
ENST00000448849.2
BIVM
basic, immunoglobulin-like variable motif containing
chr11_+_59480899 0.65 ENST00000300150.7
STX3
syntaxin 3
chr3_-_122512619 0.65 ENST00000383659.1
ENST00000306103.2
HSPBAP1
HSPB (heat shock 27kDa) associated protein 1
chr2_+_47630255 0.64 ENST00000406134.1
MSH2
mutS homolog 2
chr1_-_33168336 0.62 ENST00000373484.3
SYNC
syncoilin, intermediate filament protein
chr11_-_66445219 0.62 ENST00000525754.1
ENST00000531969.1
ENST00000524637.1
ENST00000531036.2
ENST00000310046.4
RBM4B
RNA binding motif protein 4B
chr17_-_61523622 0.59 ENST00000448884.2
ENST00000582297.1
ENST00000582034.1
ENST00000578072.1
ENST00000360793.3
CYB561
cytochrome b561
chr10_-_126849588 0.58 ENST00000411419.2
CTBP2
C-terminal binding protein 2
chr9_-_86432547 0.58 ENST00000376365.3
ENST00000376371.2
GKAP1
G kinase anchoring protein 1
chr22_-_19165917 0.58 ENST00000451283.1
SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chrX_+_54835493 0.57 ENST00000396224.1
MAGED2
melanoma antigen family D, 2
chr15_-_56035177 0.56 ENST00000389286.4
ENST00000561292.1
PRTG
protogenin
chr12_+_51632666 0.56 ENST00000604900.1
DAZAP2
DAZ associated protein 2
chr17_-_61523535 0.55 ENST00000584031.1
ENST00000392976.1
CYB561
cytochrome b561
chr19_-_54693401 0.55 ENST00000338624.6
MBOAT7
membrane bound O-acyltransferase domain containing 7
chr8_-_74659068 0.55 ENST00000523558.1
ENST00000521210.1
ENST00000355780.5
ENST00000524104.1
ENST00000521736.1
ENST00000521447.1
ENST00000517542.1
ENST00000521451.1
ENST00000521419.1
ENST00000518502.1
ENST00000524300.1
STAU2
staufen double-stranded RNA binding protein 2
chr4_+_154125565 0.55 ENST00000338700.5
TRIM2
tripartite motif containing 2
chr15_+_82722225 0.54 ENST00000300515.8
GOLGA6L9
golgin A6 family-like 9
chr4_-_144621828 0.54 ENST00000329798.5
FREM3
FRAS1 related extracellular matrix 3
chr22_-_29137771 0.53 ENST00000439200.1
ENST00000405598.1
ENST00000398017.2
ENST00000425190.2
ENST00000348295.3
ENST00000382578.1
ENST00000382565.1
ENST00000382566.1
ENST00000382580.2
ENST00000328354.6
CHEK2
checkpoint kinase 2
chr14_-_90085458 0.53 ENST00000345097.4
ENST00000555855.1
ENST00000555353.1
FOXN3
forkhead box N3
chr12_-_125348329 0.53 ENST00000546215.1
ENST00000415380.2
ENST00000261693.6
ENST00000376788.1
ENST00000545493.1
SCARB1
scavenger receptor class B, member 1
chr2_+_47630108 0.52 ENST00000233146.2
ENST00000454849.1
ENST00000543555.1
MSH2
mutS homolog 2
chr15_+_83098710 0.51 ENST00000561062.1
ENST00000358583.3
GOLGA6L9
golgin A6 family-like 20
chr5_+_31532373 0.50 ENST00000325366.9
ENST00000355907.3
ENST00000507818.2
C5orf22
chromosome 5 open reading frame 22
chr17_+_78075498 0.49 ENST00000302262.3
GAA
glucosidase, alpha; acid
chr18_-_812231 0.49 ENST00000314574.4
YES1
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chr22_-_29663954 0.48 ENST00000216085.7
RHBDD3
rhomboid domain containing 3
chr14_+_68086515 0.48 ENST00000261783.3
ARG2
arginase 2
chr19_-_58864848 0.48 ENST00000263100.3
A1BG
alpha-1-B glycoprotein
chr9_-_79009414 0.48 ENST00000376736.1
RFK
riboflavin kinase
chr7_+_30068260 0.47 ENST00000440706.2
PLEKHA8
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8
chr22_-_29138386 0.47 ENST00000544772.1
CHEK2
checkpoint kinase 2
chr9_+_131037623 0.45 ENST00000495313.1
ENST00000372898.2
SWI5
SWI5 recombination repair homolog (yeast)
chr19_+_6373715 0.45 ENST00000599849.1
ALKBH7
alkB, alkylation repair homolog 7 (E. coli)
chr1_+_11866207 0.45 ENST00000312413.6
ENST00000346436.6
CLCN6
chloride channel, voltage-sensitive 6
chr15_+_76135622 0.45 ENST00000338677.4
ENST00000267938.4
ENST00000569423.1
UBE2Q2
ubiquitin-conjugating enzyme E2Q family member 2
chr11_-_130184470 0.45 ENST00000357899.4
ENST00000397753.1
ZBTB44
zinc finger and BTB domain containing 44
chr1_+_174969262 0.44 ENST00000406752.1
ENST00000405362.1
CACYBP
calcyclin binding protein
chr19_-_40030861 0.44 ENST00000390658.2
EID2
EP300 interacting inhibitor of differentiation 2
chr9_-_79009048 0.44 ENST00000490113.1
RFK
riboflavin kinase
chr1_-_154928562 0.43 ENST00000368463.3
ENST00000539880.1
ENST00000542459.1
ENST00000368460.3
ENST00000368465.1
PBXIP1
pre-B-cell leukemia homeobox interacting protein 1
chr11_+_10326612 0.43 ENST00000534464.1
ENST00000530439.1
ENST00000524948.1
ENST00000528655.1
ENST00000526492.1
ENST00000525063.1
ADM
adrenomedullin
chr19_-_12992274 0.43 ENST00000592506.1
ENST00000222219.3
DNASE2
deoxyribonuclease II, lysosomal
chr18_-_812517 0.42 ENST00000584307.1
YES1
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chr1_-_16939976 0.41 ENST00000430580.2
NBPF1
neuroblastoma breakpoint family, member 1
chr3_-_142607740 0.41 ENST00000485766.1
PCOLCE2
procollagen C-endopeptidase enhancer 2
chr1_+_29241027 0.41 ENST00000373797.1
EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr9_-_125027079 0.41 ENST00000417201.3
RBM18
RNA binding motif protein 18
chr9_+_124030338 0.40 ENST00000449773.1
ENST00000432226.1
ENST00000436847.1
ENST00000394353.2
ENST00000449733.1
ENST00000412819.1
ENST00000341272.2
ENST00000373808.2
GSN
gelsolin
chr13_+_103451548 0.40 ENST00000419638.1
BIVM
basic, immunoglobulin-like variable motif containing
chr15_+_23255242 0.39 ENST00000450802.3
GOLGA8I
golgin A8 family, member I
chr15_-_23692381 0.39 ENST00000567107.1
ENST00000345070.5
ENST00000312015.5
GOLGA6L2
golgin A6 family-like 2
chr10_+_94608218 0.38 ENST00000371543.1
EXOC6
exocyst complex component 6
chr3_+_45067659 0.37 ENST00000296130.4
CLEC3B
C-type lectin domain family 3, member B
chr15_-_37393406 0.37 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2
Meis homeobox 2
chr6_-_146285455 0.36 ENST00000367505.2
SHPRH
SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase
chr9_-_140009130 0.36 ENST00000497375.1
ENST00000371579.2
DPP7
dipeptidyl-peptidase 7
chr12_-_122107549 0.35 ENST00000355329.3
MORN3
MORN repeat containing 3
chr6_+_96025341 0.35 ENST00000369293.1
ENST00000358812.4
MANEA
mannosidase, endo-alpha
chr17_+_2207238 0.35 ENST00000575840.1
ENST00000576620.1
ENST00000576848.1
ENST00000574987.1
SRR
serine racemase
chr1_-_109203648 0.35 ENST00000370031.1
HENMT1
HEN1 methyltransferase homolog 1 (Arabidopsis)
chr3_-_69435224 0.34 ENST00000398540.3
FRMD4B
FERM domain containing 4B
chr3_+_184529929 0.34 ENST00000287546.4
ENST00000437079.3
VPS8
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr4_-_76439483 0.34 ENST00000380840.2
ENST00000513257.1
ENST00000507014.1
RCHY1
ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
chr17_+_48172639 0.34 ENST00000503176.1
ENST00000503614.1
PDK2
pyruvate dehydrogenase kinase, isozyme 2
chr1_-_109203685 0.32 ENST00000402983.1
ENST00000420055.1
HENMT1
HEN1 methyltransferase homolog 1 (Arabidopsis)
chr19_+_34972543 0.32 ENST00000590071.2
WTIP
Wilms tumor 1 interacting protein
chr6_+_32006042 0.32 ENST00000418967.2
CYP21A2
cytochrome P450, family 21, subfamily A, polypeptide 2
chr9_-_132597529 0.32 ENST00000372447.3
C9orf78
chromosome 9 open reading frame 78
chr11_-_19082216 0.32 ENST00000329773.2
MRGPRX2
MAS-related GPR, member X2
chr6_-_146285221 0.32 ENST00000367503.3
ENST00000438092.2
ENST00000275233.7
SHPRH
SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase
chr9_+_131038425 0.31 ENST00000320188.5
ENST00000608796.1
ENST00000419867.2
ENST00000418976.1
SWI5
SWI5 recombination repair homolog (yeast)
chr6_+_32006159 0.30 ENST00000478281.1
ENST00000471671.1
ENST00000435122.2
CYP21A2
cytochrome P450, family 21, subfamily A, polypeptide 2
chr7_-_30544405 0.30 ENST00000409390.1
ENST00000409144.1
ENST00000005374.6
ENST00000409436.1
ENST00000275428.4
GGCT
gamma-glutamylcyclotransferase
chr14_-_106066376 0.30 ENST00000412518.1
ENST00000428654.1
ENST00000427543.1
ENST00000420153.1
ENST00000577108.1
ENST00000576077.1
AL928742.12
IGHE
AL928742.12
immunoglobulin heavy constant epsilon
chr11_+_101983176 0.30 ENST00000524575.1
YAP1
Yes-associated protein 1
chr9_-_135230336 0.30 ENST00000224140.5
ENST00000372169.2
ENST00000393220.1
SETX
senataxin
chr1_+_113933371 0.30 ENST00000369617.4
MAGI3
membrane associated guanylate kinase, WW and PDZ domain containing 3
chr17_+_36584662 0.29 ENST00000431231.2
ENST00000437668.3
ARHGAP23
Rho GTPase activating protein 23
chr19_+_35168567 0.29 ENST00000457781.2
ENST00000505163.1
ENST00000505242.1
ENST00000423823.2
ENST00000507959.1
ENST00000446502.2
ZNF302
zinc finger protein 302
chr16_+_4838393 0.29 ENST00000589721.1
SMIM22
small integral membrane protein 22
chr1_-_109203997 0.29 ENST00000370032.5
HENMT1
HEN1 methyltransferase homolog 1 (Arabidopsis)
chr1_-_182558374 0.29 ENST00000367559.3
ENST00000539397.1
RNASEL
ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
chr11_-_65325430 0.29 ENST00000322147.4
LTBP3
latent transforming growth factor beta binding protein 3
chr22_+_47158578 0.29 ENST00000355704.3
TBC1D22A
TBC1 domain family, member 22A
chr3_-_49726486 0.29 ENST00000449682.2
MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr12_+_112204691 0.28 ENST00000416293.3
ENST00000261733.2
ALDH2
aldehyde dehydrogenase 2 family (mitochondrial)
chr14_+_54976603 0.28 ENST00000557317.1
CGRRF1
cell growth regulator with ring finger domain 1
chr6_+_32709119 0.28 ENST00000374940.3
HLA-DQA2
major histocompatibility complex, class II, DQ alpha 2
chr4_+_170541660 0.27 ENST00000513761.1
ENST00000347613.4
CLCN3
chloride channel, voltage-sensitive 3
chr15_-_37392703 0.27 ENST00000382766.2
ENST00000444725.1
MEIS2
Meis homeobox 2
chr7_+_99746514 0.27 ENST00000341942.5
ENST00000441173.1
LAMTOR4
late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
chr19_-_16770915 0.27 ENST00000593459.1
ENST00000358726.6
ENST00000597711.1
ENST00000487416.2
CTC-429P9.4
SMIM7
Small integral membrane protein 7; Uncharacterized protein
small integral membrane protein 7
chr2_-_122407097 0.27 ENST00000409078.3
CLASP1
cytoplasmic linker associated protein 1
chr2_+_120770581 0.27 ENST00000263713.5
EPB41L5
erythrocyte membrane protein band 4.1 like 5
chr7_+_69064566 0.26 ENST00000403018.2
AUTS2
autism susceptibility candidate 2
chr19_+_35168633 0.26 ENST00000505365.2
ZNF302
zinc finger protein 302
chr19_-_49926698 0.26 ENST00000270631.1
PTH2
parathyroid hormone 2
chr22_+_47158518 0.26 ENST00000337137.4
ENST00000380995.1
ENST00000407381.3
TBC1D22A
TBC1 domain family, member 22A
chr21_+_35445827 0.26 ENST00000608209.1
ENST00000381151.3
SLC5A3
SLC5A3
sodium/myo-inositol cotransporter
solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
chr14_-_64194745 0.26 ENST00000247225.6
SGPP1
sphingosine-1-phosphate phosphatase 1
chr17_-_2304365 0.26 ENST00000575394.1
ENST00000174618.4
MNT
MAX network transcriptional repressor
chrX_+_153524024 0.25 ENST00000369915.3
ENST00000217905.7
TKTL1
transketolase-like 1
chr20_-_62601218 0.25 ENST00000369888.1
ZNF512B
zinc finger protein 512B
chr11_+_114310237 0.25 ENST00000539119.1
REXO2
RNA exonuclease 2
chr12_+_104324112 0.25 ENST00000299767.5
HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr15_-_52263937 0.25 ENST00000315141.5
ENST00000299601.5
LEO1
Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr20_-_3644046 0.25 ENST00000290417.2
ENST00000319242.3
GFRA4
GDNF family receptor alpha 4
chr2_-_113191096 0.24 ENST00000496537.1
ENST00000330575.5
ENST00000302558.3
RGPD8
RANBP2-like and GRIP domain containing 8
chr22_+_45072925 0.24 ENST00000006251.7
PRR5
proline rich 5 (renal)
chr15_+_85144217 0.24 ENST00000540936.1
ENST00000448803.2
ENST00000546275.1
ENST00000546148.1
ENST00000442073.3
ENST00000334141.3
ENST00000358472.3
ENST00000502939.2
ENST00000379358.3
ENST00000327179.6
ZSCAN2
zinc finger and SCAN domain containing 2
chr6_-_29324054 0.24 ENST00000543825.1
OR5V1
olfactory receptor, family 5, subfamily V, member 1
chr1_-_222763240 0.24 ENST00000352967.4
ENST00000391882.1
ENST00000543857.1
TAF1A
TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
chr1_-_226187013 0.24 ENST00000272091.7
SDE2
SDE2 telomere maintenance homolog (S. pombe)
chr16_-_18573396 0.24 ENST00000543392.1
ENST00000381474.3
ENST00000330537.6
NOMO2
NODAL modulator 2
chr10_+_135207623 0.24 ENST00000317502.6
ENST00000432508.3
MTG1
mitochondrial ribosome-associated GTPase 1
chr4_-_178363581 0.24 ENST00000264595.2
AGA
aspartylglucosaminidase
chr1_+_222791417 0.24 ENST00000344922.5
ENST00000344441.6
ENST00000344507.1
MIA3
melanoma inhibitory activity family, member 3
chr16_+_3019552 0.24 ENST00000572687.1
PAQR4
progestin and adipoQ receptor family member IV
chr2_-_122407007 0.24 ENST00000263710.4
ENST00000455322.2
ENST00000397587.3
ENST00000541377.1
CLASP1
cytoplasmic linker associated protein 1
chr7_-_108166505 0.24 ENST00000426128.2
ENST00000427008.1
ENST00000388728.5
ENST00000257694.8
ENST00000422087.1
ENST00000453144.1
ENST00000436062.1
PNPLA8
patatin-like phospholipase domain containing 8
chr13_-_52733510 0.24 ENST00000378101.2
NEK3
NIMA-related kinase 3
chr16_+_3019246 0.24 ENST00000318782.8
ENST00000293978.8
PAQR4
progestin and adipoQ receptor family member IV
chr2_+_209131059 0.24 ENST00000422495.1
ENST00000452564.1
PIKFYVE
phosphoinositide kinase, FYVE finger containing
chr19_+_37342547 0.23 ENST00000331800.4
ENST00000586646.1
ZNF345
zinc finger protein 345
chr1_-_222763101 0.23 ENST00000391883.2
ENST00000366890.1
TAF1A
TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
chr9_+_131799213 0.23 ENST00000358369.4
ENST00000406926.2
ENST00000277475.5
ENST00000450073.1
FAM73B
family with sequence similarity 73, member B
chr16_+_68119440 0.23 ENST00000346183.3
ENST00000329524.4
NFATC3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr5_+_65440032 0.23 ENST00000334121.6
SREK1
splicing regulatory glutamine/lysine-rich protein 1
chr10_+_120967072 0.23 ENST00000392870.2
GRK5
G protein-coupled receptor kinase 5
chr1_-_222763214 0.23 ENST00000350027.4
TAF1A
TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
chr12_+_57998595 0.23 ENST00000337737.3
ENST00000548198.1
ENST00000551632.1
DTX3
deltex homolog 3 (Drosophila)
chr11_-_105948040 0.22 ENST00000534815.1
KBTBD3
kelch repeat and BTB (POZ) domain containing 3
chr19_+_8478154 0.22 ENST00000381035.4
ENST00000595142.1
ENST00000601724.1
ENST00000393944.1
ENST00000215555.2
ENST00000601283.1
ENST00000595213.1
MARCH2
membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
chr11_-_89224139 0.22 ENST00000413594.2
NOX4
NADPH oxidase 4
chr19_+_17337406 0.22 ENST00000597836.1
OCEL1
occludin/ELL domain containing 1
chrX_+_101975643 0.22 ENST00000361229.4
BHLHB9
basic helix-loop-helix domain containing, class B, 9
chr17_-_35969409 0.22 ENST00000394378.2
ENST00000585472.1
ENST00000591288.1
ENST00000502449.2
ENST00000345615.4
ENST00000346661.4
ENST00000585689.1
ENST00000339208.6
SYNRG
synergin, gamma
chr1_-_113498616 0.22 ENST00000433570.4
ENST00000538576.1
ENST00000458229.1
SLC16A1
solute carrier family 16 (monocarboxylate transporter), member 1
chr1_+_113933581 0.22 ENST00000307546.9
ENST00000369615.1
ENST00000369611.4
MAGI3
membrane associated guanylate kinase, WW and PDZ domain containing 3
chr2_+_238969530 0.22 ENST00000254663.6
ENST00000555827.1
ENST00000373332.3
ENST00000413463.1
ENST00000409736.2
ENST00000422984.2
ENST00000412508.1
ENST00000429612.2
SCLY
selenocysteine lyase
chrX_+_101975619 0.22 ENST00000457056.1
BHLHB9
basic helix-loop-helix domain containing, class B, 9
chr10_+_23728198 0.22 ENST00000376495.3
OTUD1
OTU domain containing 1
chr16_+_16326352 0.22 ENST00000399336.4
ENST00000263012.6
ENST00000538468.1
NOMO3
NODAL modulator 3
chrX_+_107334895 0.22 ENST00000372232.3
ENST00000345734.3
ENST00000372254.3
ATG4A
autophagy related 4A, cysteine peptidase
chr16_-_57219721 0.22 ENST00000562406.1
ENST00000568671.1
ENST00000567044.1
FAM192A
family with sequence similarity 192, member A
chr9_-_116840728 0.22 ENST00000265132.3
AMBP
alpha-1-microglobulin/bikunin precursor
chr11_+_114310164 0.21 ENST00000544196.1
ENST00000539754.1
ENST00000539275.1
REXO2
RNA exonuclease 2
chr12_-_108954933 0.21 ENST00000431469.2
ENST00000546815.1
SART3
squamous cell carcinoma antigen recognized by T cells 3
chr11_+_93474786 0.21 ENST00000331239.4
ENST00000533585.1
ENST00000528099.1
ENST00000354421.3
ENST00000540113.1
ENST00000530620.1
ENST00000527003.1
ENST00000531650.1
ENST00000530279.1
C11orf54
chromosome 11 open reading frame 54
chr15_+_84115868 0.21 ENST00000427482.2
SH3GL3
SH3-domain GRB2-like 3
chr11_-_17410869 0.21 ENST00000528731.1
KCNJ11
potassium inwardly-rectifying channel, subfamily J, member 11
chr22_+_45072958 0.21 ENST00000403581.1
PRR5
proline rich 5 (renal)
chr1_-_23694794 0.21 ENST00000374608.3
ZNF436
zinc finger protein 436
chr1_-_22109682 0.21 ENST00000400301.1
ENST00000532737.1
USP48
ubiquitin specific peptidase 48
chr15_-_66790146 0.21 ENST00000316634.5
SNAPC5
small nuclear RNA activating complex, polypeptide 5, 19kDa
chr17_-_4463856 0.21 ENST00000574584.1
ENST00000381550.3
ENST00000301395.3
GGT6
gamma-glutamyltransferase 6
chr10_+_135207598 0.21 ENST00000477902.2
MTG1
mitochondrial ribosome-associated GTPase 1
chr22_-_31328881 0.20 ENST00000445980.1
MORC2
MORC family CW-type zinc finger 2
chr19_+_16435625 0.20 ENST00000248071.5
ENST00000592003.1
KLF2
Kruppel-like factor 2
chr1_+_220921582 0.20 ENST00000359316.2
MARC2
mitochondrial amidoxime reducing component 2
chr1_+_39547082 0.20 ENST00000602421.1
MACF1
microtubule-actin crosslinking factor 1
chr3_-_88108192 0.20 ENST00000309534.6
CGGBP1
CGG triplet repeat binding protein 1
chr1_+_215740709 0.20 ENST00000259154.4
KCTD3
potassium channel tetramerization domain containing 3

Network of associatons between targets according to the STRING database.

First level regulatory network of RARA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.4 GO:0002086 diaphragm contraction(GO:0002086)
0.3 1.0 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.3 0.9 GO:0042727 flavin-containing compound biosynthetic process(GO:0042727)
0.3 1.5 GO:0033489 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.3 0.9 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.3 1.4 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.3 1.1 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.3 1.1 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.2 0.7 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.2 1.2 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520)
0.2 1.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.2 1.1 GO:0051622 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.2 0.6 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
0.2 0.8 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.2 0.5 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.2 0.5 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.1 0.1 GO:1902957 negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957)
0.1 0.4 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.1 0.3 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.1 0.4 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.1 0.3 GO:0051780 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.1 0.9 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.1 0.6 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 0.4 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.1 0.3 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 0.2 GO:0031247 actin rod assembly(GO:0031247)
0.1 0.4 GO:0044856 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.1 0.2 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.1 0.3 GO:1902462 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.1 0.8 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.1 0.7 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.3 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.1 0.6 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 0.2 GO:2000196 positive regulation of female gonad development(GO:2000196) regulation of progesterone secretion(GO:2000870)
0.1 0.3 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.1 0.6 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.9 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.1 0.2 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 0.2 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.1 0.4 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.1 0.4 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.1 0.4 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 0.8 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.1 GO:1900158 negative regulation of osteoclast proliferation(GO:0090291) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.0 0.7 GO:0015747 urate transport(GO:0015747)
0.0 0.3 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.6 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.8 GO:0071397 cellular response to cholesterol(GO:0071397)
0.0 0.1 GO:0015993 molecular hydrogen transport(GO:0015993)
0.0 0.2 GO:0051697 protein delipidation(GO:0051697)
0.0 0.3 GO:0015798 myo-inositol transport(GO:0015798)
0.0 1.0 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.3 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.0 0.2 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.0 0.7 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 0.2 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.0 0.6 GO:0008212 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.0 0.5 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.2 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.2 GO:0001808 regulation of type IV hypersensitivity(GO:0001807) negative regulation of type IV hypersensitivity(GO:0001808)
0.0 0.2 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.2 GO:0019075 virus maturation(GO:0019075)
0.0 0.5 GO:0038203 TORC2 signaling(GO:0038203)
0.0 1.2 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0 0.2 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016)
0.0 0.1 GO:2000777 positive regulation of oocyte maturation(GO:1900195) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.0 0.1 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.0 0.7 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.5 GO:0000050 urea cycle(GO:0000050)
0.0 0.1 GO:0035552 oxidative single-stranded DNA demethylation(GO:0035552)
0.0 0.3 GO:0006772 thiamine metabolic process(GO:0006772)
0.0 0.1 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.2 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.2 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.1 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.3 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0002894 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.0 0.1 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.0 0.2 GO:0042126 nitrate metabolic process(GO:0042126)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.0 0.2 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.4 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.3 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.0 0.1 GO:0046502 uroporphyrinogen III biosynthetic process(GO:0006780) uroporphyrinogen III metabolic process(GO:0046502)
0.0 0.1 GO:0051582 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.0 0.8 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.1 GO:0061107 prostate gland stromal morphogenesis(GO:0060741) seminal vesicle development(GO:0061107)
0.0 0.1 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0035441 cell migration involved in vasculogenesis(GO:0035441)
0.0 0.1 GO:0034959 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.4 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 2.5 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 1.1 GO:0046039 GTP metabolic process(GO:0046039)
0.0 0.1 GO:0035106 operant conditioning(GO:0035106)
0.0 0.5 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 2.5 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.2 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.6 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.1 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.2 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.2 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.2 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533)
0.0 0.3 GO:0050812 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.1 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.1 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.3 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.2 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.1 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.4 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.2 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.0 0.2 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 0.3 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.2 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.4 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.1 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.7 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.4 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.1 GO:0035973 aggrephagy(GO:0035973)
0.0 0.2 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.2 GO:0090110 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872) cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.0 0.1 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.5 GO:0046710 GDP metabolic process(GO:0046710)
0.0 0.0 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.0 0.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.2 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0 0.2 GO:0031065 positive regulation of histone deacetylation(GO:0031065)
0.0 0.2 GO:0030575 nuclear body organization(GO:0030575)
0.0 0.2 GO:0033327 male sex determination(GO:0030238) Leydig cell differentiation(GO:0033327)
0.0 0.3 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.4 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.3 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.4 GO:0006517 protein deglycosylation(GO:0006517)
0.0 0.1 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.0 0.3 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 0.2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0032302 MutSbeta complex(GO:0032302)
0.2 0.9 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.2 1.3 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.2 0.8 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.2 0.6 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.1 0.7 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 0.5 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 0.3 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 0.3 GO:0097224 sperm connecting piece(GO:0097224)
0.1 0.3 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 0.2 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.1 0.6 GO:0097470 ribbon synapse(GO:0097470)
0.1 0.4 GO:0001652 granular component(GO:0001652)
0.1 2.4 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 0.2 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.3 GO:0033263 CORVET complex(GO:0033263)
0.1 0.3 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.2 GO:0071001 U4/U6 snRNP(GO:0071001)
0.1 0.6 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.7 GO:0031209 SCAR complex(GO:0031209)
0.0 0.9 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.0 1.0 GO:0045495 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.3 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.2 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.2 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.1 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 0.4 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 1.0 GO:1902555 endoribonuclease complex(GO:1902555)
0.0 0.1 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.2 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.2 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.5 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.5 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 2.1 GO:0005604 basement membrane(GO:0005604)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 1.3 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 0.0 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.9 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.7 GO:0000786 nucleosome(GO:0000786)
0.0 0.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.4 1.2 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.4 1.2 GO:0000404 heteroduplex DNA loop binding(GO:0000404) double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.3 1.1 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.2 0.7 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.2 1.1 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.2 0.9 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.2 0.5 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.1 0.8 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.8 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.4 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.1 0.4 GO:0047661 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.1 0.5 GO:0017089 glycolipid transporter activity(GO:0017089)
0.1 0.7 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 0.3 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.1 0.7 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 0.3 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 0.3 GO:0001147 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1 0.6 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1 0.5 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.2 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 1.1 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.7 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.1 0.2 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.1 0.2 GO:0004915 interleukin-6 receptor activity(GO:0004915) leukemia inhibitory factor receptor activity(GO:0004923) interleukin-6 binding(GO:0019981)
0.1 0.3 GO:0004802 transketolase activity(GO:0004802)
0.1 0.6 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 0.2 GO:0019862 IgA binding(GO:0019862)
0.1 0.2 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.2 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 0.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.1 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.0 0.1 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.2 GO:0016936 galactoside binding(GO:0016936)
0.0 0.7 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.1 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.0 0.2 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 1.5 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.2 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.2 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.1 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0 0.2 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.2 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0 0.1 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0 0.2 GO:0043813 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.0 0.3 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.2 GO:0070363 mitochondrial light strand promoter sense binding(GO:0070363)
0.0 0.2 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.5 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.4 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0038131 neuregulin receptor activity(GO:0038131)
0.0 0.5 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 0.1 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.2 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.9 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.3 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.9 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.3 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.2 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0035514 DNA demethylase activity(GO:0035514)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.3 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.3 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.3 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591) dopamine neurotransmitter receptor activity(GO:0004952)
0.0 0.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.2 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
0.0 0.6 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.1 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.2 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0016015 morphogen activity(GO:0016015)
0.0 0.9 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.2 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.2 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.5 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.3 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.0 GO:0090541 MIT domain binding(GO:0090541)
0.0 0.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.1 GO:0071933 Arp2/3 complex binding(GO:0071933)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 2.8 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.0 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 2.2 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.4 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 1.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.9 PID ATM PATHWAY ATM pathway
0.0 0.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.3 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.1 3.1 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.9 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 1.1 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.7 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 1.4 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.6 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.9 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 1.1 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.7 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.7 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.1 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.6 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 1.5 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.3 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.2 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.2 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling