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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for RARB

Z-value: 0.87

Motif logo

Transcription factors associated with RARB

Gene Symbol Gene ID Gene Info
ENSG00000077092.14 retinoic acid receptor beta

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RARBhg19_v2_chr3_+_25469724_254697730.638.2e-04Click!

Activity profile of RARB motif

Sorted Z-values of RARB motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_93963590 2.04 ENST00000340600.2
suppressor of cytokine signaling 2
chr10_-_33625154 1.91 ENST00000265371.4
neuropilin 1
chr1_+_221051699 1.89 ENST00000366903.6
H2.0-like homeobox
chr8_+_84824920 1.82 ENST00000523678.1
RP11-120I21.2
chr17_+_58677539 1.73 ENST00000305921.3
protein phosphatase, Mg2+/Mn2+ dependent, 1D
chr14_+_22964877 1.61 ENST00000390494.1
T cell receptor alpha joining 43
chrX_-_119709637 1.36 ENST00000404115.3
cullin 4B
chr5_-_55412774 1.28 ENST00000434982.2
ankyrin repeat domain 55
chr12_+_20522179 1.23 ENST00000359062.3
phosphodiesterase 3A, cGMP-inhibited
chr11_+_121447469 1.21 ENST00000532694.1
ENST00000534286.1
sortilin-related receptor, L(DLR class) A repeats containing
chr8_-_95274536 1.20 ENST00000297596.2
ENST00000396194.2
GTP binding protein overexpressed in skeletal muscle
chr9_-_100459639 1.18 ENST00000375128.4
xeroderma pigmentosum, complementation group A
chr8_+_74903580 1.09 ENST00000284818.2
ENST00000518893.1
lymphocyte antigen 96
chr21_-_31859755 1.06 ENST00000334055.3
keratin associated protein 19-2
chr9_-_125590818 1.04 ENST00000259467.4
phosducin-like
chr6_+_24495185 1.01 ENST00000348925.2
aldehyde dehydrogenase 5 family, member A1
chr14_+_89290965 0.96 ENST00000345383.5
ENST00000536576.1
ENST00000346301.4
ENST00000338104.6
ENST00000354441.6
ENST00000380656.2
ENST00000556651.1
ENST00000554686.1
tetratricopeptide repeat domain 8
chrX_-_134429952 0.96 ENST00000370764.1
zinc finger protein 75D
chr9_+_104296122 0.95 ENST00000389120.3
ring finger protein 20, E3 ubiquitin protein ligase
chr8_+_67624653 0.94 ENST00000521198.2
serum/glucocorticoid regulated kinase family, member 3
chr19_-_46142637 0.93 ENST00000590043.1
ENST00000589876.1
echinoderm microtubule associated protein like 2
chr6_+_24495067 0.92 ENST00000357578.3
ENST00000546278.1
ENST00000491546.1
aldehyde dehydrogenase 5 family, member A1
chr2_+_132286754 0.90 ENST00000434330.1
coiled-coil domain containing 74A
chr17_-_62097904 0.86 ENST00000583366.1
intercellular adhesion molecule 2
chr4_-_141075330 0.85 ENST00000509479.2
mastermind-like 3 (Drosophila)
chr7_-_5998714 0.84 ENST00000539903.1
radial spoke head 10 homolog B (Chlamydomonas)
chr6_+_147527103 0.84 ENST00000179882.6
syntaxin binding protein 5 (tomosyn)
chr5_-_141392538 0.82 ENST00000503794.1
ENST00000510194.1
ENST00000504424.1
ENST00000513454.1
ENST00000458112.2
ENST00000542860.1
ENST00000503229.1
ENST00000500692.2
ENST00000311337.6
ENST00000504139.1
ENST00000505689.1
glucosamine-6-phosphate deaminase 1
chr11_+_95523621 0.79 ENST00000325542.5
ENST00000325486.5
ENST00000544522.1
ENST00000541365.1
centrosomal protein 57kDa
chr6_-_52859046 0.78 ENST00000457564.1
ENST00000541324.1
ENST00000370960.1
glutathione S-transferase alpha 4
chr2_+_132287237 0.78 ENST00000467992.2
coiled-coil domain containing 74A
chr6_+_49431073 0.77 ENST00000335783.3
centromere protein Q
chr6_-_49430886 0.75 ENST00000274813.3
methylmalonyl CoA mutase
chr5_-_135290705 0.70 ENST00000274507.1
leukocyte cell-derived chemotaxin 2
chr11_+_31531291 0.70 ENST00000350638.5
ENST00000379163.5
ENST00000395934.2
elongator acetyltransferase complex subunit 4
chr6_-_51952418 0.70 ENST00000371117.3
polycystic kidney and hepatic disease 1 (autosomal recessive)
chr1_+_159750720 0.70 ENST00000368109.1
ENST00000368108.3
dual specificity phosphatase 23
chr1_-_150979333 0.69 ENST00000312210.5
family with sequence similarity 63, member A
chrX_+_73164167 0.69 ENST00000414209.1
ENST00000602895.1
ENST00000453317.1
ENST00000602546.1
ENST00000602985.1
ENST00000415215.1
JPX transcript, XIST activator (non-protein coding)
chr1_-_15850676 0.66 ENST00000440484.1
ENST00000333868.5
caspase 9, apoptosis-related cysteine peptidase
chr17_-_39677971 0.65 ENST00000393976.2
keratin 15
chr12_+_131438443 0.63 ENST00000261654.5
G protein-coupled receptor 133
chr19_-_41256207 0.63 ENST00000598485.2
ENST00000470681.1
ENST00000339153.3
ENST00000598729.1
chromosome 19 open reading frame 54
chr9_+_75136717 0.62 ENST00000297784.5
transmembrane channel-like 1
chr10_-_65028938 0.62 ENST00000402544.1
jumonji domain containing 1C
chr17_+_76142434 0.61 ENST00000340363.5
ENST00000586999.1
chromosome 17 open reading frame 99
chr11_-_118436707 0.60 ENST00000264020.2
ENST00000264021.3
intraflagellar transport 46 homolog (Chlamydomonas)
chr9_+_35909478 0.59 ENST00000443779.1
long intergenic non-protein coding RNA 961
chrX_+_55246771 0.59 ENST00000289619.5
ENST00000374955.3
P antigen family, member 5 (prostate associated)
chr1_+_159750776 0.59 ENST00000368107.1
dual specificity phosphatase 23
chr19_-_9731872 0.58 ENST00000424629.1
ENST00000326044.5
ENST00000354661.4
ENST00000435550.1
ENST00000444611.1
ENST00000421525.1
zinc finger protein 561
chr14_-_24806588 0.57 ENST00000555591.1
ENST00000554569.1
Uncharacterized protein
receptor-interacting serine-threonine kinase 3
chr19_+_21106081 0.57 ENST00000300540.3
ENST00000595854.1
ENST00000601284.1
ENST00000328178.8
ENST00000599885.1
ENST00000596476.1
ENST00000345030.6
zinc finger protein 85
chr1_+_53392901 0.56 ENST00000371514.3
ENST00000528311.1
ENST00000371509.4
ENST00000407246.2
ENST00000371513.5
sterol carrier protein 2
chr1_+_156561533 0.55 ENST00000368234.3
ENST00000368235.3
ENST00000368233.3
apolipoprotein A-I binding protein
chr16_+_68877496 0.54 ENST00000261778.1
transport and golgi organization 6 homolog (Drosophila)
chr10_-_27389320 0.54 ENST00000436985.2
ankyrin repeat domain 26
chr7_-_99332719 0.52 ENST00000336374.2
cytochrome P450, family 3, subfamily A, polypeptide 7
chr16_+_15596123 0.51 ENST00000452191.2
chromosome 16 open reading frame 45
chr17_-_41277370 0.51 ENST00000476777.1
ENST00000491747.2
ENST00000478531.1
ENST00000477152.1
ENST00000357654.3
ENST00000493795.1
ENST00000493919.1
breast cancer 1, early onset
chr6_+_31674639 0.50 ENST00000556581.1
ENST00000375832.4
ENST00000503322.1
lymphocyte antigen 6 complex, locus G6F
HCG43720, isoform CRA_a; Lymphocyte antigen 6 complex locus protein G6f; Megakaryocyte-enhanced gene transcript 1 protein; Uncharacterized protein
chr19_+_5914213 0.50 ENST00000222125.5
ENST00000452990.2
ENST00000588865.1
calcyphosine
chr10_-_65028817 0.48 ENST00000542921.1
jumonji domain containing 1C
chrX_+_73164149 0.46 ENST00000602938.1
ENST00000602294.1
ENST00000602920.1
ENST00000602737.1
ENST00000602772.1
JPX transcript, XIST activator (non-protein coding)
chr1_+_52521797 0.46 ENST00000313334.8
basic transcription factor 3-like 4
chr1_+_35544968 0.46 ENST00000359858.4
ENST00000373330.1
zinc finger, MYM-type 1
chr2_-_208994548 0.46 ENST00000282141.3
crystallin, gamma C
chr17_-_41277317 0.46 ENST00000497488.1
ENST00000489037.1
ENST00000470026.1
ENST00000586385.1
ENST00000591534.1
ENST00000591849.1
breast cancer 1, early onset
chr4_+_124317940 0.44 ENST00000505319.1
ENST00000339241.1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr15_+_81591757 0.43 ENST00000558332.1
interleukin 16
chr5_+_99871004 0.43 ENST00000312637.4
family with sequence similarity 174, member A
chr17_-_73267304 0.43 ENST00000579297.1
ENST00000580571.1
MIF4G domain containing
chr4_-_100140331 0.42 ENST00000407820.2
ENST00000394897.1
ENST00000508558.1
ENST00000394899.2
alcohol dehydrogenase 6 (class V)
chr17_-_6338399 0.42 ENST00000570584.1
ENST00000574913.1
ENST00000571740.1
ENST00000575265.1
ENST00000574506.1
aryl hydrocarbon receptor interacting protein-like 1
chr4_+_56719782 0.41 ENST00000381295.2
ENST00000346134.7
ENST00000349598.6
exocyst complex component 1
chr19_+_21541732 0.41 ENST00000311015.3
zinc finger protein 738
chr1_-_79472365 0.41 ENST00000370742.3
EGF, latrophilin and seven transmembrane domain containing 1
chr11_-_63381925 0.39 ENST00000415826.1
phospholipase A2, group XVI
chr5_+_53751445 0.39 ENST00000302005.1
heat shock 27kDa protein 3
chr10_+_47894572 0.39 ENST00000355876.5
family with sequence similarity 21, member B
chr11_-_129817471 0.39 ENST00000423662.2
PR domain containing 10
chr2_-_175499294 0.38 ENST00000392547.2
WAS/WASL interacting protein family, member 1
chr8_+_39770803 0.37 ENST00000518237.1
indoleamine 2,3-dioxygenase 1
chr19_+_39881951 0.37 ENST00000315588.5
ENST00000594368.1
ENST00000599213.2
ENST00000596297.1
mediator complex subunit 29
chr7_-_123198284 0.36 ENST00000355749.2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr5_+_147774275 0.36 ENST00000513826.1
F-box protein 38
chr6_-_132834184 0.35 ENST00000367941.2
ENST00000367937.4
syntaxin 7
chr1_-_52521831 0.35 ENST00000371626.4
thioredoxin domain containing 12 (endoplasmic reticulum)
chr7_+_158649242 0.35 ENST00000407559.3
WD repeat domain 60
chr9_+_131217459 0.34 ENST00000497812.2
ENST00000393533.2
outer dense fiber of sperm tails 2
chr6_+_170615819 0.34 ENST00000476287.1
ENST00000252510.9
family with sequence similarity 120B
chr19_+_21688366 0.34 ENST00000358491.4
ENST00000597078.1
zinc finger protein 429
chr1_+_52521928 0.33 ENST00000489308.2
basic transcription factor 3-like 4
chr8_+_62737875 0.32 ENST00000523042.1
ENST00000518593.1
ENST00000519452.1
ENST00000519967.1
RP11-705O24.1
chr12_-_113658892 0.31 ENST00000299732.2
ENST00000416617.2
IQ motif containing D
chr10_-_27530997 0.31 ENST00000375901.1
ENST00000412279.1
ENST00000375905.4
acyl-CoA binding domain containing 5
chr5_+_446253 0.30 ENST00000315013.5
exocyst complex component 3
chr5_-_75008244 0.30 ENST00000510798.1
ENST00000446329.2
POC5 centriolar protein
chr4_-_147443043 0.30 ENST00000394059.4
ENST00000502607.1
ENST00000335472.7
ENST00000432059.2
ENST00000394062.3
solute carrier family 10, member 7
chr4_+_8594477 0.30 ENST00000315782.6
carboxypeptidase Z
chr12_+_4130143 0.30 ENST00000543206.1
RP11-320N7.2
chr19_+_42363917 0.29 ENST00000598742.1
ribosomal protein S19
chr20_-_32262165 0.29 ENST00000606690.1
ENST00000246190.6
ENST00000439478.1
ENST00000375238.4
N-terminal EF-hand calcium binding protein 3
chr17_-_46178527 0.29 ENST00000393408.3
chromobox homolog 1
chr2_+_29117509 0.29 ENST00000407426.3
WD repeat domain 43
chr11_-_63381823 0.29 ENST00000323646.5
phospholipase A2, group XVI
chr6_-_52149475 0.28 ENST00000419835.2
ENST00000229854.7
ENST00000596288.1
minichromosome maintenance complex component 3
chr18_-_19283649 0.28 ENST00000584464.1
ENST00000578270.1
abhydrolase domain containing 3
chr2_-_176866978 0.28 ENST00000392540.2
ENST00000409660.1
ENST00000544803.1
ENST00000272748.4
KIAA1715
chr17_+_73997419 0.27 ENST00000425876.2
cyclin-dependent kinase 3
chr1_-_32687923 0.27 ENST00000309777.6
ENST00000344461.3
ENST00000373593.1
ENST00000545122.1
transmembrane protein 234
chr2_-_97405775 0.27 ENST00000264963.4
ENST00000537039.1
ENST00000377079.4
ENST00000426463.2
ENST00000534882.1
lectin, mannose-binding 2-like
chr6_+_76311568 0.27 ENST00000370014.3
SUMO1/sentrin specific peptidase 6
chr18_-_21852143 0.27 ENST00000399443.3
oxysterol binding protein-like 1A
chr11_-_506316 0.26 ENST00000532055.1
ENST00000531540.1
ribonuclease/angiogenin inhibitor 1
chr2_+_68592305 0.26 ENST00000234313.7
pleckstrin
chr6_-_51952367 0.26 ENST00000340994.4
polycystic kidney and hepatic disease 1 (autosomal recessive)
chr13_-_30881134 0.26 ENST00000380617.3
ENST00000441394.1
katanin p60 subunit A-like 1
chr4_+_8594364 0.26 ENST00000360986.4
carboxypeptidase Z
chr13_+_28519343 0.26 ENST00000381026.3
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit pseudogene 2
chr10_-_70287231 0.25 ENST00000609923.1
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16
chr16_-_4852915 0.25 ENST00000322048.7
rogdi homolog (Drosophila)
chr6_+_132891461 0.25 ENST00000275198.1
trace amine associated receptor 6
chr4_+_8594435 0.24 ENST00000382480.2
carboxypeptidase Z
chr12_+_57943781 0.24 ENST00000455537.2
ENST00000286452.5
kinesin family member 5A
chr17_+_74846230 0.24 ENST00000592919.1
long intergenic non-protein coding RNA 868
chr10_+_6779326 0.24 ENST00000417112.1
RP11-554I8.2
chr4_-_84406218 0.23 ENST00000515303.1
family with sequence similarity 175, member A
chrX_+_129535937 0.23 ENST00000305536.6
ENST00000370947.1
RNA binding motif protein, X-linked 2
chr2_+_217082311 0.23 ENST00000597904.1
RP11-566E18.3
chr17_-_46178741 0.23 ENST00000581003.1
ENST00000225603.4
chromobox homolog 1
chr15_+_40531243 0.23 ENST00000558055.1
ENST00000455577.2
p21 protein (Cdc42/Rac)-activated kinase 6
chr12_+_57810198 0.23 ENST00000598001.1
HCG1818482; Uncharacterized protein
chr19_+_39279838 0.22 ENST00000314980.4
lectin, galactoside-binding, soluble, 7B
chr11_-_122931881 0.22 ENST00000526110.1
ENST00000227378.3
heat shock 70kDa protein 8
chr15_-_74504597 0.22 ENST00000416286.3
stimulated by retinoic acid 6
chr2_+_119981384 0.22 ENST00000393108.2
ENST00000354888.5
ENST00000450943.2
ENST00000393110.2
ENST00000393106.2
ENST00000409811.1
ENST00000393107.2
STEAP family member 3, metalloreductase
chr17_-_28618948 0.22 ENST00000261714.6
bleomycin hydrolase
chr19_+_44669280 0.22 ENST00000590089.1
ENST00000454662.2
zinc finger protein 226
chr1_+_1846519 0.22 ENST00000378604.3
calmodulin-like 6
chr10_+_5932174 0.22 ENST00000362091.4
F-box protein, helicase, 18
chr6_+_24667257 0.21 ENST00000537591.1
ENST00000230048.4
acyl-CoA thioesterase 13
chr3_+_127317066 0.21 ENST00000265056.7
minichromosome maintenance complex component 2
chrX_-_14047996 0.21 ENST00000380523.4
ENST00000398355.3
gem (nuclear organelle) associated protein 8
chr1_+_160313062 0.21 ENST00000294785.5
ENST00000368063.1
ENST00000437169.1
nicastrin
chr18_-_24765248 0.21 ENST00000580774.1
ENST00000284224.8
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr1_+_16330723 0.21 ENST00000329454.2
chromosome 1 open reading frame 64
chr7_-_93519471 0.20 ENST00000451238.1
tissue factor pathway inhibitor 2
chr7_-_6098770 0.20 ENST00000536084.1
ENST00000446699.1
ENST00000199389.6
eukaryotic translation initiation factor 2-alpha kinase 1
chr8_+_91013676 0.19 ENST00000519410.1
ENST00000522161.1
ENST00000517761.1
ENST00000520227.1
2,4-dienoyl CoA reductase 1, mitochondrial
chr11_-_321050 0.19 ENST00000399808.4
interferon induced transmembrane protein 3
chr2_+_177025619 0.19 ENST00000410016.1
homeobox D3
chr1_+_1215968 0.19 ENST00000338555.2
sodium channel, non-voltage-gated 1, delta subunit
chr22_-_31063782 0.19 ENST00000404885.1
ENST00000403268.1
ENST00000407308.1
ENST00000342474.4
ENST00000334679.3
dual specificity phosphatase 18
chr1_-_46642154 0.19 ENST00000540385.1
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr6_+_139456226 0.18 ENST00000367658.2
headcase homolog (Drosophila)
chr17_+_13972807 0.18 ENST00000429152.2
ENST00000261643.3
ENST00000536205.1
ENST00000537334.1
cytochrome c oxidase assembly homolog 10 (yeast)
chr22_-_43036607 0.18 ENST00000505920.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G2
chr11_+_118938485 0.18 ENST00000300793.6
vacuolar protein sorting 11 homolog (S. cerevisiae)
chr1_-_21044489 0.17 ENST00000247986.2
kinesin family member 17
chr1_-_86861660 0.17 ENST00000486215.1
outer dense fiber of sperm tails 2-like
chr1_+_174669653 0.17 ENST00000325589.5
RAB GTPase activating protein 1-like
chr8_-_27462822 0.16 ENST00000522098.1
clusterin
chr6_+_76311736 0.16 ENST00000447266.2
SUMO1/sentrin specific peptidase 6
chr12_+_113796347 0.16 ENST00000545182.2
ENST00000280800.3
phospholipase B domain containing 2
chr19_-_15344243 0.16 ENST00000602233.1
epoxide hydrolase 3
chr9_-_104145795 0.16 ENST00000259407.2
bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)
chr7_-_144533074 0.15 ENST00000360057.3
ENST00000378099.3
thiamin pyrophosphokinase 1
chr1_+_1215816 0.15 ENST00000379116.5
sodium channel, non-voltage-gated 1, delta subunit
chr11_+_63870660 0.15 ENST00000246841.3
fibronectin leucine rich transmembrane protein 1
chr11_-_796197 0.15 ENST00000530360.1
ENST00000528606.1
ENST00000320230.5
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr2_+_11679963 0.14 ENST00000263834.5
growth regulation by estrogen in breast cancer 1
chr8_+_48873453 0.14 ENST00000523944.1
minichromosome maintenance complex component 4
chr2_+_220492116 0.14 ENST00000373760.2
solute carrier family 4 (anion exchanger), member 3
chr2_-_152830441 0.13 ENST00000534999.1
ENST00000397327.2
calcium channel, voltage-dependent, beta 4 subunit
chr16_-_20587599 0.13 ENST00000566384.1
ENST00000565232.1
ENST00000567001.1
ENST00000565322.1
ENST00000569344.1
ENST00000329697.6
ENST00000414188.2
ENST00000568882.1
acyl-CoA synthetase medium-chain family member 2B
chr6_-_2751146 0.13 ENST00000268446.5
ENST00000274643.7
myosin light chain kinase family, member 4
chr16_+_56995854 0.13 ENST00000566128.1
cholesteryl ester transfer protein, plasma
chr2_-_136594740 0.13 ENST00000264162.2
lactase
chr11_+_111783450 0.13 ENST00000537382.1
Homo sapiens heat shock 27kDa protein 2 (HSPB2), mRNA.
chr17_+_48046538 0.13 ENST00000240306.3
distal-less homeobox 4
chr6_-_71012773 0.13 ENST00000370496.3
ENST00000357250.6
collagen, type IX, alpha 1
chr1_+_52521957 0.12 ENST00000472944.2
ENST00000484036.1
basic transcription factor 3-like 4
chr19_-_22193706 0.12 ENST00000597040.1
zinc finger protein 208
chr11_+_61520075 0.12 ENST00000278836.5
myelin regulatory factor
chr2_+_74361599 0.11 ENST00000401851.1
MGC10955
chr18_-_24722995 0.11 ENST00000581714.1
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr1_+_66258846 0.11 ENST00000341517.4
phosphodiesterase 4B, cAMP-specific
chr15_-_54051831 0.11 ENST00000557913.1
ENST00000360509.5
WD repeat domain 72
chr10_+_11784360 0.11 ENST00000379215.4
ENST00000420401.1
enoyl CoA hydratase domain containing 3
chr1_+_155278539 0.11 ENST00000447866.1
farnesyl diphosphate synthase
chr1_+_59775752 0.10 ENST00000371212.1
FGGY carbohydrate kinase domain containing
chr8_+_91013577 0.10 ENST00000220764.2
2,4-dienoyl CoA reductase 1, mitochondrial
chr19_+_6361440 0.10 ENST00000245816.4
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr15_+_38226827 0.10 ENST00000559502.1
ENST00000558148.1
ENST00000558158.1
transmembrane and coiled-coil domains 5A
chr22_+_22749343 0.09 ENST00000390298.2
immunoglobulin lambda variable 7-43
chrX_-_100546314 0.09 ENST00000356784.1
TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa
chr7_-_44180884 0.09 ENST00000458240.1
ENST00000223364.3
myosin, light chain 7, regulatory
chr19_+_51273721 0.09 ENST00000270590.4
G protein-coupled receptor 32
chr13_+_73302047 0.09 ENST00000377814.2
ENST00000377815.3
ENST00000390667.5
bora, aurora kinase A activator

Network of associatons between targets according to the STRING database.

First level regulatory network of RARB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:1902955 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.4 1.9 GO:0021649 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.3 1.0 GO:0070510 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
0.3 1.9 GO:0009450 acetate metabolic process(GO:0006083) gamma-aminobutyric acid catabolic process(GO:0009450)
0.3 1.2 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 1.9 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.2 1.0 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.2 1.2 GO:0071321 cellular response to cGMP(GO:0071321)
0.2 0.6 GO:0035698 CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:0035698) positive regulation of necroptotic process(GO:0060545) regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:2000452)
0.2 0.9 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.2 1.1 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.1 0.4 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.1 2.5 GO:0070914 UV-damage excision repair(GO:0070914)
0.1 0.4 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.1 0.8 GO:0006041 glucosamine metabolic process(GO:0006041)
0.1 0.8 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.1 1.0 GO:0050893 sensory processing(GO:0050893)
0.1 1.9 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.4 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 0.4 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.1 0.6 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.5 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.1 2.0 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 0.8 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.6 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1 0.4 GO:0036269 swimming behavior(GO:0036269)
0.1 0.9 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.1 0.3 GO:0060266 positive regulation of respiratory burst involved in inflammatory response(GO:0060265) negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1 0.4 GO:0018343 protein farnesylation(GO:0018343)
0.1 0.7 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.2 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.1 1.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.2 GO:0006447 regulation of translational initiation by iron(GO:0006447)
0.0 0.3 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.7 GO:0032025 response to cobalt ion(GO:0032025)
0.0 0.2 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0 0.2 GO:0061143 alveolar primary septum development(GO:0061143)
0.0 0.3 GO:0030242 pexophagy(GO:0030242)
0.0 0.3 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 0.2 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.0 0.2 GO:0043418 homocysteine catabolic process(GO:0043418)
0.0 0.4 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.6 GO:0051601 exocyst localization(GO:0051601)
0.0 0.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.3 GO:0051013 microtubule severing(GO:0051013)
0.0 0.3 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 0.2 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.2 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.7 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.3 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.8 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:0045337 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.0 0.1 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 1.0 GO:0010824 regulation of centrosome duplication(GO:0010824)
0.0 0.8 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.2 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.9 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.4 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.3 GO:0045023 G0 to G1 transition(GO:0045023)
0.0 0.2 GO:0019530 taurine metabolic process(GO:0019530)
0.0 0.2 GO:0055091 phospholipid homeostasis(GO:0055091)
0.0 0.4 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.3 GO:0035357 peroxisome proliferator activated receptor signaling pathway(GO:0035357)
0.0 0.4 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.2 1.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 1.9 GO:0097443 sorting endosome(GO:0097443)
0.2 1.4 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.2 1.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.2 0.7 GO:0043293 apoptosome(GO:0043293)
0.1 0.9 GO:0033503 HULC complex(GO:0033503)
0.1 0.4 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.1 0.4 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.1 1.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 1.0 GO:0034464 BBSome(GO:0034464)
0.1 0.5 GO:0001940 male pronucleus(GO:0001940)
0.1 0.4 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.6 GO:0032426 stereocilium tip(GO:0032426)
0.0 1.0 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.3 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.2 GO:1990075 periciliary membrane compartment(GO:1990075)
0.0 0.6 GO:0042555 MCM complex(GO:0042555)
0.0 0.8 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.3 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 1.2 GO:0051233 spindle midzone(GO:0051233)
0.0 0.8 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.2 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.6 GO:0097342 ripoptosome(GO:0097342)
0.0 0.3 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.3 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.2 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.6 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.7 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.2 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 1.6 GO:0044439 microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.0 0.2 GO:0030897 HOPS complex(GO:0030897)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.3 2.0 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.2 1.0 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.2 1.9 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.2 0.6 GO:0070538 oleic acid binding(GO:0070538)
0.2 1.0 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 0.4 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.1 1.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.2 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.1 0.3 GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670)
0.1 0.7 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 0.8 GO:0031419 cobalamin binding(GO:0031419)
0.1 1.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 1.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.5 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 0.6 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 0.2 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.6 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 0.3 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.1 0.4 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 1.3 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.8 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0017129 triglyceride binding(GO:0017129)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.6 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 1.7 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 1.9 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0 3.5 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.2 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.1 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 1.1 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.3 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.0 0.2 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.3 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.4 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.4 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.7 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.4 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.2 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.3 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 1.2 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.0 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.8 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 1.4 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.0 GO:0004917 interleukin-4 receptor activity(GO:0004913) interleukin-7 receptor activity(GO:0004917)
0.0 0.9 GO:0002039 p53 binding(GO:0002039)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.0 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.9 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.7 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 2.1 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 1.0 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.7 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.9 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.7 PID INSULIN PATHWAY Insulin Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 1.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 0.8 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.1 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 2.1 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 1.0 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 1.7 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.7 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.2 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.7 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.6 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.7 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.4 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.2 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.1 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.8 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere