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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for RBPJ

Z-value: 0.50

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Transcription factors associated with RBPJ

Gene Symbol Gene ID Gene Info
RBPJ
ENSG00000168214.16 recombination signal binding protein for immunoglobulin kappa J region

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RBPJhg19_v2_chr4_+_26321284_26321377,
hg19_v2_chr4_+_26322409_26322479		-0.019.5e-01Click!

Activity profile of RBPJ motif

Sorted Z-values of RBPJ motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_49259643 1.38 ENST00000309739.5
RND1
Rho family GTPase 1
chr8_-_80680078 1.34 ENST00000337919.5
ENST00000354724.3
HEY1
hes-related family bHLH transcription factor with YRPW motif 1
chr1_-_935491 1.00 ENST00000304952.6
HES4
hes family bHLH transcription factor 4
chr6_-_76203345 0.75 ENST00000393004.2
FILIP1
filamin A interacting protein 1
chr1_+_61869748 0.72 ENST00000357977.5
NFIA
nuclear factor I/A
chr3_+_46449049 0.67 ENST00000357392.4
ENST00000400880.3
ENST00000433848.1
CCRL2
chemokine (C-C motif) receptor-like 2
chr6_-_76203454 0.61 ENST00000237172.7
FILIP1
filamin A interacting protein 1
chr1_-_935361 0.59 ENST00000484667.2
HES4
hes family bHLH transcription factor 4
chr16_+_53738053 0.58 ENST00000394647.3
FTO
fat mass and obesity associated
chr1_+_61547894 0.52 ENST00000403491.3
NFIA
nuclear factor I/A
chr15_-_70390191 0.51 ENST00000559191.1
TLE3
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr15_-_70390213 0.51 ENST00000557997.1
ENST00000317509.8
ENST00000442299.2
TLE3
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr13_-_20357110 0.50 ENST00000427943.1
PSPC1
paraspeckle component 1
chr7_-_22259845 0.46 ENST00000420196.1
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr9_+_102584128 0.45 ENST00000338488.4
ENST00000395097.2
NR4A3
nuclear receptor subfamily 4, group A, member 3
chr1_-_935519 0.45 ENST00000428771.2
HES4
hes family bHLH transcription factor 4
chr12_-_7848364 0.44 ENST00000329913.3
GDF3
growth differentiation factor 3
chr1_+_61547405 0.44 ENST00000371189.4
NFIA
nuclear factor I/A
chr10_+_115439630 0.43 ENST00000369318.3
CASP7
caspase 7, apoptosis-related cysteine peptidase
chr8_-_101348408 0.40 ENST00000519527.1
ENST00000522369.1
RNF19A
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr10_-_33623826 0.39 ENST00000374867.2
NRP1
neuropilin 1
chr10_-_33623564 0.37 ENST00000374875.1
ENST00000374822.4
NRP1
neuropilin 1
chr15_+_67418047 0.34 ENST00000540846.2
SMAD3
SMAD family member 3
chr13_-_20357057 0.33 ENST00000338910.4
PSPC1
paraspeckle component 1
chr10_-_33624002 0.33 ENST00000432372.2
NRP1
neuropilin 1
chr10_+_115439699 0.33 ENST00000369315.1
CASP7
caspase 7, apoptosis-related cysteine peptidase
chr11_-_64647144 0.31 ENST00000359393.2
ENST00000433803.1
ENST00000411683.1
EHD1
EH-domain containing 1
chr7_+_102553430 0.30 ENST00000339431.4
ENST00000249377.4
LRRC17
leucine rich repeat containing 17
chr5_-_88119580 0.30 ENST00000539796.1
MEF2C
myocyte enhancer factor 2C
chr18_-_52989217 0.30 ENST00000570287.2
TCF4
transcription factor 4
chr11_-_64512469 0.28 ENST00000377485.1
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr7_-_120498357 0.28 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
TSPAN12
tetraspanin 12
chr7_+_150026938 0.28 ENST00000343855.4
ZBED6CL
ZBED6 C-terminal like
chr6_+_50061315 0.27 ENST00000415106.1
RP11-397G17.1
RP11-397G17.1
chr3_+_38017264 0.26 ENST00000436654.1
CTDSPL
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr17_+_2699697 0.26 ENST00000254695.8
ENST00000366401.4
ENST00000542807.1
RAP1GAP2
RAP1 GTPase activating protein 2
chr21_+_38792602 0.25 ENST00000398960.2
ENST00000398956.2
DYRK1A
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
chr10_+_112836779 0.24 ENST00000280155.2
ADRA2A
adrenoceptor alpha 2A
chr15_+_74218787 0.24 ENST00000261921.7
LOXL1
lysyl oxidase-like 1
chr10_+_124320195 0.24 ENST00000359586.6
DMBT1
deleted in malignant brain tumors 1
chr5_+_137514834 0.24 ENST00000508792.1
ENST00000504621.1
KIF20A
kinesin family member 20A
chr10_+_124320156 0.23 ENST00000338354.3
ENST00000344338.3
ENST00000330163.4
ENST00000368909.3
ENST00000368955.3
ENST00000368956.2
DMBT1
deleted in malignant brain tumors 1
chr17_-_56606664 0.22 ENST00000580844.1
SEPT4
septin 4
chr2_+_109271481 0.22 ENST00000542845.1
ENST00000393314.2
LIMS1
LIM and senescent cell antigen-like domains 1
chr17_-_56606639 0.22 ENST00000579371.1
SEPT4
septin 4
chr5_+_137514687 0.22 ENST00000394894.3
KIF20A
kinesin family member 20A
chr17_-_56606705 0.22 ENST00000317268.3
SEPT4
septin 4
chr9_-_104357277 0.21 ENST00000374806.1
PPP3R2
protein phosphatase 3, regulatory subunit B, beta
chr11_+_66384053 0.21 ENST00000310137.4
ENST00000393979.3
ENST00000409372.1
ENST00000443702.1
ENST00000409738.4
ENST00000514361.3
ENST00000503028.2
ENST00000412278.2
ENST00000500635.2
RBM14
RBM4
RBM14-RBM4
RNA binding motif protein 14
RNA binding motif protein 4
RBM14-RBM4 readthrough
chr5_-_137071689 0.21 ENST00000505853.1
KLHL3
kelch-like family member 3
chr1_+_36690011 0.20 ENST00000354618.5
ENST00000469141.2
ENST00000478853.1
THRAP3
thyroid hormone receptor associated protein 3
chr20_+_43211149 0.20 ENST00000372886.1
PKIG
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr1_-_85870177 0.20 ENST00000542148.1
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr2_-_111230393 0.19 ENST00000447537.2
ENST00000413601.2
LIMS3L
LIMS3L
LIM and senescent cell antigen-like-containing domain protein 3; Uncharacterized protein; cDNA FLJ59124, highly similar to Particularly interesting newCys-His protein; cDNA, FLJ79109, highly similar to Particularly interesting newCys-His protein
LIM and senescent cell antigen-like domains 3-like
chr14_+_73603126 0.19 ENST00000557356.1
ENST00000556864.1
ENST00000556533.1
ENST00000556951.1
ENST00000557293.1
ENST00000553719.1
ENST00000553599.1
ENST00000556011.1
ENST00000394157.3
ENST00000357710.4
ENST00000324501.5
ENST00000560005.2
ENST00000555254.1
ENST00000261970.3
ENST00000344094.3
ENST00000554131.1
ENST00000557037.1
PSEN1
presenilin 1
chr3_-_183735651 0.18 ENST00000427120.2
ENST00000392579.2
ENST00000382494.2
ENST00000446941.2
ABCC5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr10_-_49459800 0.18 ENST00000305531.3
FRMPD2
FERM and PDZ domain containing 2
chr3_-_183735731 0.18 ENST00000334444.6
ABCC5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr11_-_67290867 0.18 ENST00000353903.5
ENST00000294288.4
CABP2
calcium binding protein 2
chr16_-_57831914 0.16 ENST00000421376.2
KIFC3
kinesin family member C3
chr12_-_43945724 0.16 ENST00000389420.3
ENST00000553158.1
ADAMTS20
ADAM metallopeptidase with thrombospondin type 1 motif, 20
chr2_+_110656005 0.16 ENST00000437679.2
LIMS3
LIM and senescent cell antigen-like domains 3
chr7_+_30811004 0.16 ENST00000265299.6
FAM188B
family with sequence similarity 188, member B
chr1_-_40105617 0.16 ENST00000372852.3
HEYL
hes-related family bHLH transcription factor with YRPW motif-like
chr5_-_137514617 0.15 ENST00000254900.5
BRD8
bromodomain containing 8
chr5_+_140792614 0.15 ENST00000398610.2
PCDHGA10
protocadherin gamma subfamily A, 10
chr11_-_790060 0.15 ENST00000330106.4
CEND1
cell cycle exit and neuronal differentiation 1
chr2_+_219135115 0.15 ENST00000248451.3
ENST00000273077.4
PNKD
paroxysmal nonkinesigenic dyskinesia
chr14_+_24701628 0.14 ENST00000355299.4
ENST00000559836.1
GMPR2
guanosine monophosphate reductase 2
chr1_-_146644036 0.14 ENST00000425272.2
PRKAB2
protein kinase, AMP-activated, beta 2 non-catalytic subunit
chr19_+_50706866 0.14 ENST00000440075.2
ENST00000376970.2
ENST00000425460.1
ENST00000599920.1
ENST00000601313.1
MYH14
myosin, heavy chain 14, non-muscle
chr5_+_147258266 0.13 ENST00000296694.4
SCGB3A2
secretoglobin, family 3A, member 2
chr19_-_55690758 0.12 ENST00000590851.1
SYT5
synaptotagmin V
chr2_-_129076151 0.12 ENST00000259241.6
HS6ST1
heparan sulfate 6-O-sulfotransferase 1
chr15_-_77988485 0.12 ENST00000561030.1
LINGO1
leucine rich repeat and Ig domain containing 1
chr2_+_204193101 0.12 ENST00000430418.1
ENST00000424558.1
ENST00000261016.6
ABI2
abl-interactor 2
chr13_-_74708372 0.11 ENST00000377666.4
KLF12
Kruppel-like factor 12
chr5_-_139943830 0.11 ENST00000412920.3
ENST00000511201.2
ENST00000356738.2
ENST00000354402.5
ENST00000358580.5
ENST00000508496.2
APBB3
amyloid beta (A4) precursor protein-binding, family B, member 3
chr10_-_74927810 0.11 ENST00000372979.4
ENST00000430082.2
ENST00000454759.2
ENST00000413026.1
ENST00000453402.1
ECD
ecdysoneless homolog (Drosophila)
chr10_-_97200772 0.11 ENST00000371241.1
ENST00000354106.3
ENST00000371239.1
ENST00000361941.3
ENST00000277982.5
ENST00000371245.3
SORBS1
sorbin and SH3 domain containing 1
chrX_+_36065053 0.10 ENST00000313548.4
CHDC2
calponin homology domain containing 2
chr2_+_219824357 0.10 ENST00000302625.4
CDK5R2
cyclin-dependent kinase 5, regulatory subunit 2 (p39)
chrX_+_123095546 0.10 ENST00000371157.3
ENST00000371145.3
ENST00000371144.3
STAG2
stromal antigen 2
chr11_+_112832090 0.10 ENST00000533760.1
NCAM1
neural cell adhesion molecule 1
chr11_+_45944190 0.10 ENST00000401752.1
ENST00000389968.3
ENST00000325468.5
ENST00000536139.1
GYLTL1B
glycosyltransferase-like 1B
chr8_-_87242589 0.09 ENST00000419776.2
ENST00000297524.3
SLC7A13
solute carrier family 7 (anionic amino acid transporter), member 13
chrX_+_37865804 0.09 ENST00000297875.2
ENST00000357972.5
SYTL5
synaptotagmin-like 5
chr22_+_40297105 0.09 ENST00000540310.1
GRAP2
GRB2-related adaptor protein 2
chr5_+_85913721 0.08 ENST00000247655.3
ENST00000509578.1
ENST00000515763.1
COX7C
cytochrome c oxidase subunit VIIc
chr17_-_16118835 0.08 ENST00000582357.1
ENST00000436828.1
ENST00000411510.1
ENST00000268712.3
NCOR1
nuclear receptor corepressor 1
chr11_-_8290263 0.08 ENST00000428101.2
LMO1
LIM domain only 1 (rhombotin 1)
chr6_-_26056695 0.08 ENST00000343677.2
HIST1H1C
histone cluster 1, H1c
chr12_-_4758159 0.08 ENST00000545990.2
AKAP3
A kinase (PRKA) anchor protein 3
chrX_+_123094369 0.08 ENST00000455404.1
ENST00000218089.9
STAG2
stromal antigen 2
chr11_+_66512089 0.08 ENST00000524551.1
ENST00000525908.1
ENST00000360962.4
ENST00000346672.4
ENST00000527634.1
ENST00000540737.1
C11orf80
chromosome 11 open reading frame 80
chr14_-_53417732 0.08 ENST00000399304.3
ENST00000395631.2
ENST00000341590.3
ENST00000343279.4
FERMT2
fermitin family member 2
chr11_-_101454658 0.08 ENST00000344327.3
TRPC6
transient receptor potential cation channel, subfamily C, member 6
chr1_+_156737292 0.07 ENST00000271526.4
ENST00000353233.3
PRCC
papillary renal cell carcinoma (translocation-associated)
chr12_-_31945172 0.07 ENST00000340398.3
H3F3C
H3 histone, family 3C
chr14_-_48144157 0.07 ENST00000399232.2
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr14_-_24701539 0.07 ENST00000534348.1
ENST00000524927.1
ENST00000250495.5
NEDD8-MDP1
NEDD8
NEDD8-MDP1 readthrough
neural precursor cell expressed, developmentally down-regulated 8
chr11_+_66512303 0.07 ENST00000532565.2
C11orf80
chromosome 11 open reading frame 80
chr2_+_48796120 0.07 ENST00000394754.1
STON1-GTF2A1L
STON1-GTF2A1L readthrough
chr2_-_219134822 0.07 ENST00000444053.1
ENST00000248450.4
AAMP
angio-associated, migratory cell protein
chr5_-_175815565 0.06 ENST00000509257.1
ENST00000507413.1
ENST00000510123.1
NOP16
NOP16 nucleolar protein
chr16_+_23690138 0.06 ENST00000300093.4
PLK1
polo-like kinase 1
chr3_+_193853927 0.06 ENST00000232424.3
HES1
hes family bHLH transcription factor 1
chr17_-_27053216 0.06 ENST00000292090.3
TLCD1
TLC domain containing 1
chr20_+_30063067 0.06 ENST00000201979.2
REM1
RAS (RAD and GEM)-like GTP-binding 1
chrX_+_152907913 0.06 ENST00000370167.4
DUSP9
dual specificity phosphatase 9
chr5_+_42423872 0.06 ENST00000230882.4
ENST00000357703.3
GHR
growth hormone receptor
chr17_-_71410794 0.06 ENST00000424778.1
SDK2
sidekick cell adhesion molecule 2
chr19_-_46296011 0.06 ENST00000377735.3
ENST00000270223.6
DMWD
dystrophia myotonica, WD repeat containing
chr12_+_56623827 0.06 ENST00000424625.1
ENST00000419753.1
ENST00000454355.2
ENST00000417965.1
ENST00000436633.1
SLC39A5
solute carrier family 39 (zinc transporter), member 5
chr10_-_44144292 0.06 ENST00000374433.2
ZNF32
zinc finger protein 32
chr6_+_33176265 0.05 ENST00000374656.4
RING1
ring finger protein 1
chr22_+_40297079 0.05 ENST00000344138.4
ENST00000543252.1
GRAP2
GRB2-related adaptor protein 2
chr10_+_60144782 0.05 ENST00000487519.1
TFAM
transcription factor A, mitochondrial
chr10_-_44144152 0.05 ENST00000395797.1
ZNF32
zinc finger protein 32
chr2_+_159825143 0.05 ENST00000454300.1
ENST00000263635.6
TANC1
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chr19_+_39390587 0.05 ENST00000572515.1
ENST00000392079.3
ENST00000575359.1
ENST00000313582.5
NFKBIB
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr13_+_39612485 0.05 ENST00000379599.2
NHLRC3
NHL repeat containing 3
chr19_-_39694894 0.05 ENST00000318438.6
SYCN
syncollin
chr19_-_36870087 0.05 ENST00000270001.7
ZFP14
ZFP14 zinc finger protein
chr1_-_112531777 0.05 ENST00000315987.2
ENST00000302127.4
KCND3
potassium voltage-gated channel, Shal-related subfamily, member 3
chr1_-_197744390 0.05 ENST00000367396.3
DENND1B
DENN/MADD domain containing 1B
chr16_+_85645007 0.05 ENST00000405402.2
GSE1
Gse1 coiled-coil protein
chr16_-_30102547 0.05 ENST00000279386.2
TBX6
T-box 6
chr8_-_67974552 0.05 ENST00000357849.4
COPS5
COP9 signalosome subunit 5
chr7_+_90339169 0.04 ENST00000436577.2
CDK14
cyclin-dependent kinase 14
chr11_+_64053311 0.04 ENST00000540370.1
GPR137
G protein-coupled receptor 137
chr3_-_19975665 0.04 ENST00000295824.9
ENST00000389256.4
EFHB
EF-hand domain family, member B
chr10_-_33623310 0.04 ENST00000395995.1
ENST00000374823.5
ENST00000374821.5
ENST00000374816.3
NRP1
neuropilin 1
chr14_+_22337014 0.04 ENST00000390436.2
TRAV13-1
T cell receptor alpha variable 13-1
chr17_-_66097610 0.04 ENST00000584047.1
ENST00000579629.1
AC145343.2
AC145343.2
chr3_-_87325728 0.04 ENST00000350375.2
POU1F1
POU class 1 homeobox 1
chr15_+_59730348 0.04 ENST00000288228.5
ENST00000559628.1
ENST00000557914.1
ENST00000560474.1
FAM81A
family with sequence similarity 81, member A
chr7_+_90338712 0.04 ENST00000265741.3
ENST00000406263.1
CDK14
cyclin-dependent kinase 14
chr16_+_23313591 0.04 ENST00000343070.2
SCNN1B
sodium channel, non-voltage-gated 1, beta subunit
chr3_-_87325612 0.03 ENST00000561167.1
ENST00000560656.1
ENST00000344265.3
POU1F1
POU class 1 homeobox 1
chr17_-_34257731 0.03 ENST00000431884.2
ENST00000425909.3
ENST00000394528.3
ENST00000430160.2
RDM1
RAD52 motif 1
chr11_-_64512803 0.03 ENST00000377489.1
ENST00000354024.3
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr17_-_34257771 0.03 ENST00000394529.3
ENST00000293273.6
RDM1
RAD52 motif 1
chrX_-_73834449 0.03 ENST00000332687.6
ENST00000349225.2
RLIM
ring finger protein, LIM domain interacting
chr13_+_39612442 0.03 ENST00000470258.1
ENST00000379600.3
NHLRC3
NHL repeat containing 3
chr11_+_111789580 0.03 ENST00000278601.5
C11orf52
chromosome 11 open reading frame 52
chr20_+_44637526 0.03 ENST00000372330.3
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr2_+_3642545 0.03 ENST00000382062.2
ENST00000236693.7
ENST00000349077.4
COLEC11
collectin sub-family member 11
chr6_-_31510181 0.03 ENST00000458640.1
ENST00000396172.1
ENST00000417556.2
DDX39B
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr9_-_35691017 0.03 ENST00000378292.3
TPM2
tropomyosin 2 (beta)
chr19_-_39390440 0.03 ENST00000249396.7
ENST00000414941.1
ENST00000392081.2
SIRT2
sirtuin 2
chr19_+_7660716 0.02 ENST00000160298.4
ENST00000446248.2
CAMSAP3
calmodulin regulated spectrin-associated protein family, member 3
chr1_+_185126291 0.02 ENST00000367500.4
SWT1
SWT1 RNA endoribonuclease homolog (S. cerevisiae)
chr1_+_43855560 0.02 ENST00000562955.1
SZT2
seizure threshold 2 homolog (mouse)
chr2_+_187350973 0.02 ENST00000544130.1
ZC3H15
zinc finger CCCH-type containing 15
chr5_+_175815732 0.02 ENST00000274787.2
HIGD2A
HIG1 hypoxia inducible domain family, member 2A
chr13_-_25496926 0.02 ENST00000545981.1
ENST00000381884.4
CENPJ
centromere protein J
chr6_-_134373732 0.02 ENST00000275230.5
SLC2A12
solute carrier family 2 (facilitated glucose transporter), member 12
chr1_-_150980828 0.02 ENST00000361936.5
ENST00000361738.6
FAM63A
family with sequence similarity 63, member A
chr10_+_74927875 0.02 ENST00000242505.6
FAM149B1
family with sequence similarity 149, member B1
chr11_-_8959758 0.02 ENST00000531618.1
ASCL3
achaete-scute family bHLH transcription factor 3
chr6_+_126070726 0.02 ENST00000368364.3
HEY2
hes-related family bHLH transcription factor with YRPW motif 2
chr3_+_32726774 0.02 ENST00000538368.1
CNOT10
CCR4-NOT transcription complex, subunit 10
chr7_-_150924121 0.02 ENST00000441774.1
ENST00000222388.2
ENST00000287844.2
ABCF2
ATP-binding cassette, sub-family F (GCN20), member 2
chr12_+_106976678 0.02 ENST00000392842.1
RFX4
regulatory factor X, 4 (influences HLA class II expression)
chr11_-_83393429 0.01 ENST00000426717.2
DLG2
discs, large homolog 2 (Drosophila)
chr8_-_22089845 0.01 ENST00000454243.2
PHYHIP
phytanoyl-CoA 2-hydroxylase interacting protein
chr20_+_32250079 0.01 ENST00000375222.3
C20orf144
chromosome 20 open reading frame 144
chr16_+_21964662 0.01 ENST00000561553.1
ENST00000565331.1
UQCRC2
ubiquinol-cytochrome c reductase core protein II
chr8_-_22089533 0.01 ENST00000321613.3
PHYHIP
phytanoyl-CoA 2-hydroxylase interacting protein
chrX_+_16141667 0.01 ENST00000380289.2
GRPR
gastrin-releasing peptide receptor
chr16_+_75182376 0.01 ENST00000570010.1
ENST00000568079.1
ENST00000464850.1
ENST00000332307.4
ENST00000393430.2
ZFP1
ZFP1 zinc finger protein
chr5_-_115872142 0.01 ENST00000510263.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr3_+_159570722 0.01 ENST00000482804.1
SCHIP1
schwannomin interacting protein 1
chr7_-_16505440 0.01 ENST00000307068.4
SOSTDC1
sclerostin domain containing 1
chr1_+_161676739 0.01 ENST00000236938.6
ENST00000367959.2
ENST00000546024.1
ENST00000540521.1
ENST00000367949.2
ENST00000350710.3
ENST00000540926.1
FCRLA
Fc receptor-like A
chr16_+_72459838 0.01 ENST00000564508.1
AC004158.3
AC004158.3
chr7_+_128784712 0.01 ENST00000289407.4
TSPAN33
tetraspanin 33
chr17_+_73452545 0.01 ENST00000314256.7
KIAA0195
KIAA0195
chr17_-_39637392 0.00 ENST00000246639.2
ENST00000393989.1
KRT35
keratin 35
chr19_-_39390350 0.00 ENST00000447739.1
ENST00000358931.5
ENST00000407552.1
SIRT2
sirtuin 2
chr14_-_93214915 0.00 ENST00000553918.1
ENST00000555699.1
ENST00000553802.1
ENST00000554397.1
ENST00000554919.1
ENST00000554080.1
ENST00000553371.1
LGMN
legumain
chr1_-_85358850 0.00 ENST00000370611.3
LPAR3
lysophosphatidic acid receptor 3
chr17_+_41322483 0.00 ENST00000341165.6
ENST00000586650.1
ENST00000422280.1
NBR1
neighbor of BRCA1 gene 1
chr3_+_69812701 0.00 ENST00000472437.1
MITF
microphthalmia-associated transcription factor
chr1_+_210406121 0.00 ENST00000367012.3
SERTAD4
SERTA domain containing 4
chrX_-_49121165 0.00 ENST00000376207.4
ENST00000376199.2
FOXP3
forkhead box P3
chr1_-_197036364 0.00 ENST00000367412.1
F13B
coagulation factor XIII, B polypeptide
chr13_-_20805109 0.00 ENST00000241124.6
GJB6
gap junction protein, beta 6, 30kDa
chr20_+_30225682 0.00 ENST00000376075.3
COX4I2
cytochrome c oxidase subunit IV isoform 2 (lung)
chr10_+_31608054 0.00 ENST00000320985.10
ENST00000361642.5
ENST00000560721.2
ENST00000558440.1
ENST00000424869.1
ENST00000542815.3
ZEB1
zinc finger E-box binding homeobox 1

Network of associatons between targets according to the STRING database.

First level regulatory network of RBPJ

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.2 1.1 GO:1902378 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.2 0.6 GO:0035552 oxidative single-stranded DNA demethylation(GO:0035552)
0.2 0.5 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.1 0.7 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 0.8 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1 0.2 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.1 1.4 GO:0016322 neuron remodeling(GO:0016322)
0.1 0.3 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.3 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 1.7 GO:0072189 ureter development(GO:0072189)
0.1 0.4 GO:0048859 formation of anatomical boundary(GO:0048859)
0.1 0.2 GO:0035625 negative regulation of epinephrine secretion(GO:0032811) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.1 0.2 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.1 0.2 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.0 0.1 GO:0061727 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.5 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.3 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.0 0.3 GO:0048539 bone marrow development(GO:0048539)
0.0 0.1 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.0 0.2 GO:0021590 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.4 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.2 GO:0097167 circadian regulation of translation(GO:0097167)
0.0 0.1 GO:0045168 inhibition of neuroepithelial cell differentiation(GO:0002085) trochlear nerve development(GO:0021558) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) cell-cell signaling involved in cell fate commitment(GO:0045168) negative regulation of auditory receptor cell differentiation(GO:0045608) regulation of timing of neuron differentiation(GO:0060164)
0.0 0.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.5 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.0 0.1 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.0 1.0 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.2 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.0 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.0 0.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.1 GO:0000255 allantoin metabolic process(GO:0000255)
0.0 0.1 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.0 0.1 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0 0.2 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:0016321 female meiosis chromosome segregation(GO:0016321)
0.0 0.2 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
0.0 0.1 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.0 GO:1900195 positive regulation of oocyte maturation(GO:1900195) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0097443 sorting endosome(GO:0097443)
0.1 0.8 GO:0042382 paraspeckles(GO:0042382)
0.1 0.3 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.7 GO:0097227 sperm annulus(GO:0097227)
0.0 0.1 GO:0097513 myosin II filament(GO:0097513)
0.0 0.5 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.1 GO:1902560 GMP reductase complex(GO:1902560)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0070195 growth hormone receptor complex(GO:0070195)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.5 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 0.1 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0035939 microsatellite binding(GO:0035939)
0.2 0.6 GO:0035514 DNA demethylase activity(GO:0035514)
0.1 1.1 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 0.2 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.1 0.2 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.1 0.3 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.1 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.5 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.1 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.2 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.1 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.4 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.8 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.3 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.3 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.7 GO:0004950 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.5 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.0 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.3 GO:0048156 tau protein binding(GO:0048156)
0.0 0.2 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0070363 mitochondrial light strand promoter sense binding(GO:0070363)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.6 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.6 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.5 ST GA12 PATHWAY G alpha 12 Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 2.5 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.8 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.4 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins
0.0 0.6 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.2 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.6 REACTOME MYOGENESIS Genes involved in Myogenesis