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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for RBPJ

Z-value: 0.50

Motif logo

Transcription factors associated with RBPJ

Gene Symbol Gene ID Gene Info
ENSG00000168214.16 recombination signal binding protein for immunoglobulin kappa J region

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RBPJhg19_v2_chr4_+_26321284_26321377,
hg19_v2_chr4_+_26322409_26322479
-0.019.5e-01Click!

Activity profile of RBPJ motif

Sorted Z-values of RBPJ motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_49259643 1.38 ENST00000309739.5
Rho family GTPase 1
chr8_-_80680078 1.34 ENST00000337919.5
ENST00000354724.3
hes-related family bHLH transcription factor with YRPW motif 1
chr1_-_935491 1.00 ENST00000304952.6
hes family bHLH transcription factor 4
chr6_-_76203345 0.75 ENST00000393004.2
filamin A interacting protein 1
chr1_+_61869748 0.72 ENST00000357977.5
nuclear factor I/A
chr3_+_46449049 0.67 ENST00000357392.4
ENST00000400880.3
ENST00000433848.1
chemokine (C-C motif) receptor-like 2
chr6_-_76203454 0.61 ENST00000237172.7
filamin A interacting protein 1
chr1_-_935361 0.59 ENST00000484667.2
hes family bHLH transcription factor 4
chr16_+_53738053 0.58 ENST00000394647.3
fat mass and obesity associated
chr1_+_61547894 0.52 ENST00000403491.3
nuclear factor I/A
chr15_-_70390191 0.51 ENST00000559191.1
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr15_-_70390213 0.51 ENST00000557997.1
ENST00000317509.8
ENST00000442299.2
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr13_-_20357110 0.50 ENST00000427943.1
paraspeckle component 1
chr7_-_22259845 0.46 ENST00000420196.1
Rap guanine nucleotide exchange factor (GEF) 5
chr9_+_102584128 0.45 ENST00000338488.4
ENST00000395097.2
nuclear receptor subfamily 4, group A, member 3
chr1_-_935519 0.45 ENST00000428771.2
hes family bHLH transcription factor 4
chr12_-_7848364 0.44 ENST00000329913.3
growth differentiation factor 3
chr1_+_61547405 0.44 ENST00000371189.4
nuclear factor I/A
chr10_+_115439630 0.43 ENST00000369318.3
caspase 7, apoptosis-related cysteine peptidase
chr8_-_101348408 0.40 ENST00000519527.1
ENST00000522369.1
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr10_-_33623826 0.39 ENST00000374867.2
neuropilin 1
chr10_-_33623564 0.37 ENST00000374875.1
ENST00000374822.4
neuropilin 1
chr15_+_67418047 0.34 ENST00000540846.2
SMAD family member 3
chr13_-_20357057 0.33 ENST00000338910.4
paraspeckle component 1
chr10_-_33624002 0.33 ENST00000432372.2
neuropilin 1
chr10_+_115439699 0.33 ENST00000369315.1
caspase 7, apoptosis-related cysteine peptidase
chr11_-_64647144 0.31 ENST00000359393.2
ENST00000433803.1
ENST00000411683.1
EH-domain containing 1
chr7_+_102553430 0.30 ENST00000339431.4
ENST00000249377.4
leucine rich repeat containing 17
chr5_-_88119580 0.30 ENST00000539796.1
myocyte enhancer factor 2C
chr18_-_52989217 0.30 ENST00000570287.2
transcription factor 4
chr11_-_64512469 0.28 ENST00000377485.1
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr7_-_120498357 0.28 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
tetraspanin 12
chr7_+_150026938 0.28 ENST00000343855.4
ZBED6 C-terminal like
chr6_+_50061315 0.27 ENST00000415106.1
RP11-397G17.1
chr3_+_38017264 0.26 ENST00000436654.1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr17_+_2699697 0.26 ENST00000254695.8
ENST00000366401.4
ENST00000542807.1
RAP1 GTPase activating protein 2
chr21_+_38792602 0.25 ENST00000398960.2
ENST00000398956.2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
chr10_+_112836779 0.24 ENST00000280155.2
adrenoceptor alpha 2A
chr15_+_74218787 0.24 ENST00000261921.7
lysyl oxidase-like 1
chr10_+_124320195 0.24 ENST00000359586.6
deleted in malignant brain tumors 1
chr5_+_137514834 0.24 ENST00000508792.1
ENST00000504621.1
kinesin family member 20A
chr10_+_124320156 0.23 ENST00000338354.3
ENST00000344338.3
ENST00000330163.4
ENST00000368909.3
ENST00000368955.3
ENST00000368956.2
deleted in malignant brain tumors 1
chr17_-_56606664 0.22 ENST00000580844.1
septin 4
chr2_+_109271481 0.22 ENST00000542845.1
ENST00000393314.2
LIM and senescent cell antigen-like domains 1
chr17_-_56606639 0.22 ENST00000579371.1
septin 4
chr5_+_137514687 0.22 ENST00000394894.3
kinesin family member 20A
chr17_-_56606705 0.22 ENST00000317268.3
septin 4
chr9_-_104357277 0.21 ENST00000374806.1
protein phosphatase 3, regulatory subunit B, beta
chr11_+_66384053 0.21 ENST00000310137.4
ENST00000393979.3
ENST00000409372.1
ENST00000443702.1
ENST00000409738.4
ENST00000514361.3
ENST00000503028.2
ENST00000412278.2
ENST00000500635.2
RNA binding motif protein 14
RNA binding motif protein 4
RBM14-RBM4 readthrough
chr5_-_137071689 0.21 ENST00000505853.1
kelch-like family member 3
chr1_+_36690011 0.20 ENST00000354618.5
ENST00000469141.2
ENST00000478853.1
thyroid hormone receptor associated protein 3
chr20_+_43211149 0.20 ENST00000372886.1
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr1_-_85870177 0.20 ENST00000542148.1
dimethylarginine dimethylaminohydrolase 1
chr2_-_111230393 0.19 ENST00000447537.2
ENST00000413601.2
LIM and senescent cell antigen-like-containing domain protein 3; Uncharacterized protein; cDNA FLJ59124, highly similar to Particularly interesting newCys-His protein; cDNA, FLJ79109, highly similar to Particularly interesting newCys-His protein
LIM and senescent cell antigen-like domains 3-like
chr14_+_73603126 0.19 ENST00000557356.1
ENST00000556864.1
ENST00000556533.1
ENST00000556951.1
ENST00000557293.1
ENST00000553719.1
ENST00000553599.1
ENST00000556011.1
ENST00000394157.3
ENST00000357710.4
ENST00000324501.5
ENST00000560005.2
ENST00000555254.1
ENST00000261970.3
ENST00000344094.3
ENST00000554131.1
ENST00000557037.1
presenilin 1
chr3_-_183735651 0.18 ENST00000427120.2
ENST00000392579.2
ENST00000382494.2
ENST00000446941.2
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr10_-_49459800 0.18 ENST00000305531.3
FERM and PDZ domain containing 2
chr3_-_183735731 0.18 ENST00000334444.6
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr11_-_67290867 0.18 ENST00000353903.5
ENST00000294288.4
calcium binding protein 2
chr16_-_57831914 0.16 ENST00000421376.2
kinesin family member C3
chr12_-_43945724 0.16 ENST00000389420.3
ENST00000553158.1
ADAM metallopeptidase with thrombospondin type 1 motif, 20
chr2_+_110656005 0.16 ENST00000437679.2
LIM and senescent cell antigen-like domains 3
chr7_+_30811004 0.16 ENST00000265299.6
family with sequence similarity 188, member B
chr1_-_40105617 0.16 ENST00000372852.3
hes-related family bHLH transcription factor with YRPW motif-like
chr5_-_137514617 0.15 ENST00000254900.5
bromodomain containing 8
chr5_+_140792614 0.15 ENST00000398610.2
protocadherin gamma subfamily A, 10
chr11_-_790060 0.15 ENST00000330106.4
cell cycle exit and neuronal differentiation 1
chr2_+_219135115 0.15 ENST00000248451.3
ENST00000273077.4
paroxysmal nonkinesigenic dyskinesia
chr14_+_24701628 0.14 ENST00000355299.4
ENST00000559836.1
guanosine monophosphate reductase 2
chr1_-_146644036 0.14 ENST00000425272.2
protein kinase, AMP-activated, beta 2 non-catalytic subunit
chr19_+_50706866 0.14 ENST00000440075.2
ENST00000376970.2
ENST00000425460.1
ENST00000599920.1
ENST00000601313.1
myosin, heavy chain 14, non-muscle
chr5_+_147258266 0.13 ENST00000296694.4
secretoglobin, family 3A, member 2
chr19_-_55690758 0.12 ENST00000590851.1
synaptotagmin V
chr2_-_129076151 0.12 ENST00000259241.6
heparan sulfate 6-O-sulfotransferase 1
chr15_-_77988485 0.12 ENST00000561030.1
leucine rich repeat and Ig domain containing 1
chr2_+_204193101 0.12 ENST00000430418.1
ENST00000424558.1
ENST00000261016.6
abl-interactor 2
chr13_-_74708372 0.11 ENST00000377666.4
Kruppel-like factor 12
chr5_-_139943830 0.11 ENST00000412920.3
ENST00000511201.2
ENST00000356738.2
ENST00000354402.5
ENST00000358580.5
ENST00000508496.2
amyloid beta (A4) precursor protein-binding, family B, member 3
chr10_-_74927810 0.11 ENST00000372979.4
ENST00000430082.2
ENST00000454759.2
ENST00000413026.1
ENST00000453402.1
ecdysoneless homolog (Drosophila)
chr10_-_97200772 0.11 ENST00000371241.1
ENST00000354106.3
ENST00000371239.1
ENST00000361941.3
ENST00000277982.5
ENST00000371245.3
sorbin and SH3 domain containing 1
chrX_+_36065053 0.10 ENST00000313548.4
calponin homology domain containing 2
chr2_+_219824357 0.10 ENST00000302625.4
cyclin-dependent kinase 5, regulatory subunit 2 (p39)
chrX_+_123095546 0.10 ENST00000371157.3
ENST00000371145.3
ENST00000371144.3
stromal antigen 2
chr11_+_112832090 0.10 ENST00000533760.1
neural cell adhesion molecule 1
chr11_+_45944190 0.10 ENST00000401752.1
ENST00000389968.3
ENST00000325468.5
ENST00000536139.1
glycosyltransferase-like 1B
chr8_-_87242589 0.09 ENST00000419776.2
ENST00000297524.3
solute carrier family 7 (anionic amino acid transporter), member 13
chrX_+_37865804 0.09 ENST00000297875.2
ENST00000357972.5
synaptotagmin-like 5
chr22_+_40297105 0.09 ENST00000540310.1
GRB2-related adaptor protein 2
chr5_+_85913721 0.08 ENST00000247655.3
ENST00000509578.1
ENST00000515763.1
cytochrome c oxidase subunit VIIc
chr17_-_16118835 0.08 ENST00000582357.1
ENST00000436828.1
ENST00000411510.1
ENST00000268712.3
nuclear receptor corepressor 1
chr11_-_8290263 0.08 ENST00000428101.2
LIM domain only 1 (rhombotin 1)
chr6_-_26056695 0.08 ENST00000343677.2
histone cluster 1, H1c
chr12_-_4758159 0.08 ENST00000545990.2
A kinase (PRKA) anchor protein 3
chrX_+_123094369 0.08 ENST00000455404.1
ENST00000218089.9
stromal antigen 2
chr11_+_66512089 0.08 ENST00000524551.1
ENST00000525908.1
ENST00000360962.4
ENST00000346672.4
ENST00000527634.1
ENST00000540737.1
chromosome 11 open reading frame 80
chr14_-_53417732 0.08 ENST00000399304.3
ENST00000395631.2
ENST00000341590.3
ENST00000343279.4
fermitin family member 2
chr11_-_101454658 0.08 ENST00000344327.3
transient receptor potential cation channel, subfamily C, member 6
chr1_+_156737292 0.07 ENST00000271526.4
ENST00000353233.3
papillary renal cell carcinoma (translocation-associated)
chr12_-_31945172 0.07 ENST00000340398.3
H3 histone, family 3C
chr14_-_48144157 0.07 ENST00000399232.2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr14_-_24701539 0.07 ENST00000534348.1
ENST00000524927.1
ENST00000250495.5
NEDD8-MDP1 readthrough
neural precursor cell expressed, developmentally down-regulated 8
chr11_+_66512303 0.07 ENST00000532565.2
chromosome 11 open reading frame 80
chr2_+_48796120 0.07 ENST00000394754.1
STON1-GTF2A1L readthrough
chr2_-_219134822 0.07 ENST00000444053.1
ENST00000248450.4
angio-associated, migratory cell protein
chr5_-_175815565 0.06 ENST00000509257.1
ENST00000507413.1
ENST00000510123.1
NOP16 nucleolar protein
chr16_+_23690138 0.06 ENST00000300093.4
polo-like kinase 1
chr3_+_193853927 0.06 ENST00000232424.3
hes family bHLH transcription factor 1
chr17_-_27053216 0.06 ENST00000292090.3
TLC domain containing 1
chr20_+_30063067 0.06 ENST00000201979.2
RAS (RAD and GEM)-like GTP-binding 1
chrX_+_152907913 0.06 ENST00000370167.4
dual specificity phosphatase 9
chr5_+_42423872 0.06 ENST00000230882.4
ENST00000357703.3
growth hormone receptor
chr17_-_71410794 0.06 ENST00000424778.1
sidekick cell adhesion molecule 2
chr19_-_46296011 0.06 ENST00000377735.3
ENST00000270223.6
dystrophia myotonica, WD repeat containing
chr12_+_56623827 0.06 ENST00000424625.1
ENST00000419753.1
ENST00000454355.2
ENST00000417965.1
ENST00000436633.1
solute carrier family 39 (zinc transporter), member 5
chr10_-_44144292 0.06 ENST00000374433.2
zinc finger protein 32
chr6_+_33176265 0.05 ENST00000374656.4
ring finger protein 1
chr22_+_40297079 0.05 ENST00000344138.4
ENST00000543252.1
GRB2-related adaptor protein 2
chr10_+_60144782 0.05 ENST00000487519.1
transcription factor A, mitochondrial
chr10_-_44144152 0.05 ENST00000395797.1
zinc finger protein 32
chr2_+_159825143 0.05 ENST00000454300.1
ENST00000263635.6
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chr19_+_39390587 0.05 ENST00000572515.1
ENST00000392079.3
ENST00000575359.1
ENST00000313582.5
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr13_+_39612485 0.05 ENST00000379599.2
NHL repeat containing 3
chr19_-_39694894 0.05 ENST00000318438.6
syncollin
chr19_-_36870087 0.05 ENST00000270001.7
ZFP14 zinc finger protein
chr1_-_112531777 0.05 ENST00000315987.2
ENST00000302127.4
potassium voltage-gated channel, Shal-related subfamily, member 3
chr1_-_197744390 0.05 ENST00000367396.3
DENN/MADD domain containing 1B
chr16_+_85645007 0.05 ENST00000405402.2
Gse1 coiled-coil protein
chr16_-_30102547 0.05 ENST00000279386.2
T-box 6
chr8_-_67974552 0.05 ENST00000357849.4
COP9 signalosome subunit 5
chr7_+_90339169 0.04 ENST00000436577.2
cyclin-dependent kinase 14
chr11_+_64053311 0.04 ENST00000540370.1
G protein-coupled receptor 137
chr3_-_19975665 0.04 ENST00000295824.9
ENST00000389256.4
EF-hand domain family, member B
chr10_-_33623310 0.04 ENST00000395995.1
ENST00000374823.5
ENST00000374821.5
ENST00000374816.3
neuropilin 1
chr14_+_22337014 0.04 ENST00000390436.2
T cell receptor alpha variable 13-1
chr17_-_66097610 0.04 ENST00000584047.1
ENST00000579629.1
AC145343.2
chr3_-_87325728 0.04 ENST00000350375.2
POU class 1 homeobox 1
chr15_+_59730348 0.04 ENST00000288228.5
ENST00000559628.1
ENST00000557914.1
ENST00000560474.1
family with sequence similarity 81, member A
chr7_+_90338712 0.04 ENST00000265741.3
ENST00000406263.1
cyclin-dependent kinase 14
chr16_+_23313591 0.04 ENST00000343070.2
sodium channel, non-voltage-gated 1, beta subunit
chr3_-_87325612 0.03 ENST00000561167.1
ENST00000560656.1
ENST00000344265.3
POU class 1 homeobox 1
chr17_-_34257731 0.03 ENST00000431884.2
ENST00000425909.3
ENST00000394528.3
ENST00000430160.2
RAD52 motif 1
chr11_-_64512803 0.03 ENST00000377489.1
ENST00000354024.3
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr17_-_34257771 0.03 ENST00000394529.3
ENST00000293273.6
RAD52 motif 1
chrX_-_73834449 0.03 ENST00000332687.6
ENST00000349225.2
ring finger protein, LIM domain interacting
chr13_+_39612442 0.03 ENST00000470258.1
ENST00000379600.3
NHL repeat containing 3
chr11_+_111789580 0.03 ENST00000278601.5
chromosome 11 open reading frame 52
chr20_+_44637526 0.03 ENST00000372330.3
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr2_+_3642545 0.03 ENST00000382062.2
ENST00000236693.7
ENST00000349077.4
collectin sub-family member 11
chr6_-_31510181 0.03 ENST00000458640.1
ENST00000396172.1
ENST00000417556.2
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr9_-_35691017 0.03 ENST00000378292.3
tropomyosin 2 (beta)
chr19_-_39390440 0.03 ENST00000249396.7
ENST00000414941.1
ENST00000392081.2
sirtuin 2
chr19_+_7660716 0.02 ENST00000160298.4
ENST00000446248.2
calmodulin regulated spectrin-associated protein family, member 3
chr1_+_185126291 0.02 ENST00000367500.4
SWT1 RNA endoribonuclease homolog (S. cerevisiae)
chr1_+_43855560 0.02 ENST00000562955.1
seizure threshold 2 homolog (mouse)
chr2_+_187350973 0.02 ENST00000544130.1
zinc finger CCCH-type containing 15
chr5_+_175815732 0.02 ENST00000274787.2
HIG1 hypoxia inducible domain family, member 2A
chr13_-_25496926 0.02 ENST00000545981.1
ENST00000381884.4
centromere protein J
chr6_-_134373732 0.02 ENST00000275230.5
solute carrier family 2 (facilitated glucose transporter), member 12
chr1_-_150980828 0.02 ENST00000361936.5
ENST00000361738.6
family with sequence similarity 63, member A
chr10_+_74927875 0.02 ENST00000242505.6
family with sequence similarity 149, member B1
chr11_-_8959758 0.02 ENST00000531618.1
achaete-scute family bHLH transcription factor 3
chr6_+_126070726 0.02 ENST00000368364.3
hes-related family bHLH transcription factor with YRPW motif 2
chr3_+_32726774 0.02 ENST00000538368.1
CCR4-NOT transcription complex, subunit 10
chr7_-_150924121 0.02 ENST00000441774.1
ENST00000222388.2
ENST00000287844.2
ATP-binding cassette, sub-family F (GCN20), member 2
chr12_+_106976678 0.02 ENST00000392842.1
regulatory factor X, 4 (influences HLA class II expression)
chr11_-_83393429 0.01 ENST00000426717.2
discs, large homolog 2 (Drosophila)
chr8_-_22089845 0.01 ENST00000454243.2
phytanoyl-CoA 2-hydroxylase interacting protein
chr20_+_32250079 0.01 ENST00000375222.3
chromosome 20 open reading frame 144
chr16_+_21964662 0.01 ENST00000561553.1
ENST00000565331.1
ubiquinol-cytochrome c reductase core protein II
chr8_-_22089533 0.01 ENST00000321613.3
phytanoyl-CoA 2-hydroxylase interacting protein
chrX_+_16141667 0.01 ENST00000380289.2
gastrin-releasing peptide receptor
chr16_+_75182376 0.01 ENST00000570010.1
ENST00000568079.1
ENST00000464850.1
ENST00000332307.4
ENST00000393430.2
ZFP1 zinc finger protein
chr5_-_115872142 0.01 ENST00000510263.1
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr3_+_159570722 0.01 ENST00000482804.1
schwannomin interacting protein 1
chr7_-_16505440 0.01 ENST00000307068.4
sclerostin domain containing 1
chr1_+_161676739 0.01 ENST00000236938.6
ENST00000367959.2
ENST00000546024.1
ENST00000540521.1
ENST00000367949.2
ENST00000350710.3
ENST00000540926.1
Fc receptor-like A
chr16_+_72459838 0.01 ENST00000564508.1
AC004158.3
chr7_+_128784712 0.01 ENST00000289407.4
tetraspanin 33
chr17_+_73452545 0.01 ENST00000314256.7
KIAA0195
chr17_-_39637392 0.00 ENST00000246639.2
ENST00000393989.1
keratin 35
chr19_-_39390350 0.00 ENST00000447739.1
ENST00000358931.5
ENST00000407552.1
sirtuin 2
chr14_-_93214915 0.00 ENST00000553918.1
ENST00000555699.1
ENST00000553802.1
ENST00000554397.1
ENST00000554919.1
ENST00000554080.1
ENST00000553371.1
legumain
chr1_-_85358850 0.00 ENST00000370611.3
lysophosphatidic acid receptor 3
chr17_+_41322483 0.00 ENST00000341165.6
ENST00000586650.1
ENST00000422280.1
neighbor of BRCA1 gene 1
chr3_+_69812701 0.00 ENST00000472437.1
microphthalmia-associated transcription factor
chr1_+_210406121 0.00 ENST00000367012.3
SERTA domain containing 4
chrX_-_49121165 0.00 ENST00000376207.4
ENST00000376199.2
forkhead box P3
chr1_-_197036364 0.00 ENST00000367412.1
coagulation factor XIII, B polypeptide
chr13_-_20805109 0.00 ENST00000241124.6
gap junction protein, beta 6, 30kDa
chr20_+_30225682 0.00 ENST00000376075.3
cytochrome c oxidase subunit IV isoform 2 (lung)
chr10_+_31608054 0.00 ENST00000320985.10
ENST00000361642.5
ENST00000560721.2
ENST00000558440.1
ENST00000424869.1
ENST00000542815.3
zinc finger E-box binding homeobox 1

Network of associatons between targets according to the STRING database.

First level regulatory network of RBPJ

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.2 1.1 GO:1902378 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.2 0.6 GO:0035552 oxidative single-stranded DNA demethylation(GO:0035552)
0.2 0.5 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.1 0.7 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 0.8 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1 0.2 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.1 1.4 GO:0016322 neuron remodeling(GO:0016322)
0.1 0.3 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.3 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 1.7 GO:0072189 ureter development(GO:0072189)
0.1 0.4 GO:0048859 formation of anatomical boundary(GO:0048859)
0.1 0.2 GO:0035625 negative regulation of epinephrine secretion(GO:0032811) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.1 0.2 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.1 0.2 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.0 0.1 GO:0061727 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.5 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.3 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.0 0.3 GO:0048539 bone marrow development(GO:0048539)
0.0 0.1 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.0 0.2 GO:0021590 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.4 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.2 GO:0097167 circadian regulation of translation(GO:0097167)
0.0 0.1 GO:0045168 inhibition of neuroepithelial cell differentiation(GO:0002085) trochlear nerve development(GO:0021558) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) cell-cell signaling involved in cell fate commitment(GO:0045168) negative regulation of auditory receptor cell differentiation(GO:0045608) regulation of timing of neuron differentiation(GO:0060164)
0.0 0.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.5 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.0 0.1 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.0 1.0 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.2 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.0 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.0 0.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.1 GO:0000255 allantoin metabolic process(GO:0000255)
0.0 0.1 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.0 0.1 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0 0.2 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:0016321 female meiosis chromosome segregation(GO:0016321)
0.0 0.2 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
0.0 0.1 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.0 GO:1900195 positive regulation of oocyte maturation(GO:1900195) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0097443 sorting endosome(GO:0097443)
0.1 0.8 GO:0042382 paraspeckles(GO:0042382)
0.1 0.3 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.7 GO:0097227 sperm annulus(GO:0097227)
0.0 0.1 GO:0097513 myosin II filament(GO:0097513)
0.0 0.5 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.1 GO:1902560 GMP reductase complex(GO:1902560)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0070195 growth hormone receptor complex(GO:0070195)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.5 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 0.1 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0035939 microsatellite binding(GO:0035939)
0.2 0.6 GO:0035514 DNA demethylase activity(GO:0035514)
0.1 1.1 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 0.2 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.1 0.2 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.1 0.3 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.1 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.5 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.1 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.2 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.1 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.4 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.8 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.3 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.3 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.7 GO:0004950 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.5 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.0 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.3 GO:0048156 tau protein binding(GO:0048156)
0.0 0.2 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0070363 mitochondrial light strand promoter sense binding(GO:0070363)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.6 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.6 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.5 ST GA12 PATHWAY G alpha 12 Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 2.5 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.8 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.4 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins
0.0 0.6 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.2 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.6 REACTOME MYOGENESIS Genes involved in Myogenesis