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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for RELB

Z-value: 1.19

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Transcription factors associated with RELB

Gene Symbol Gene ID Gene Info
RELB
ENSG00000104856.9 RELB proto-oncogene, NF-kB subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RELBhg19_v2_chr19_+_45504688_455047820.811.1e-06Click!

Activity profile of RELB motif

Sorted Z-values of RELB motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_29527702 9.18 ENST00000377050.4
UBD
ubiquitin D
chr1_-_173020056 6.61 ENST00000239468.2
ENST00000404377.3
TNFSF18
tumor necrosis factor (ligand) superfamily, member 18
chr4_+_74702214 5.82 ENST00000226317.5
ENST00000515050.1
CXCL6
chemokine (C-X-C motif) ligand 6
chr1_+_110453109 5.49 ENST00000525659.1
CSF1
colony stimulating factor 1 (macrophage)
chr4_-_74864386 4.94 ENST00000296027.4
CXCL5
chemokine (C-X-C motif) ligand 5
chr14_+_103589789 4.92 ENST00000558056.1
ENST00000560869.1
TNFAIP2
tumor necrosis factor, alpha-induced protein 2
chr19_+_45504688 4.39 ENST00000221452.8
ENST00000540120.1
ENST00000505236.1
RELB
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr4_+_103423055 4.06 ENST00000505458.1
NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr1_-_8000872 3.95 ENST00000377507.3
TNFRSF9
tumor necrosis factor receptor superfamily, member 9
chr8_+_90770008 3.85 ENST00000540020.1
RIPK2
receptor-interacting serine-threonine kinase 2
chr5_-_61031495 3.76 ENST00000506550.1
ENST00000512882.2
CTD-2170G1.2
CTD-2170G1.2
chr6_+_138188551 3.75 ENST00000237289.4
ENST00000433680.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr6_-_32821599 3.69 ENST00000354258.4
TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr5_-_150460914 3.69 ENST00000389378.2
TNIP1
TNFAIP3 interacting protein 1
chr11_+_102188224 3.63 ENST00000263464.3
BIRC3
baculoviral IAP repeat containing 3
chr1_+_110453203 3.62 ENST00000357302.4
ENST00000344188.5
ENST00000329608.6
CSF1
colony stimulating factor 1 (macrophage)
chr5_-_150460539 3.62 ENST00000520931.1
ENST00000520695.1
ENST00000521591.1
ENST00000518977.1
TNIP1
TNFAIP3 interacting protein 1
chr12_-_49259643 3.61 ENST00000309739.5
RND1
Rho family GTPase 1
chr1_+_110453462 3.61 ENST00000488198.1
CSF1
colony stimulating factor 1 (macrophage)
chr11_+_102188272 3.43 ENST00000532808.1
BIRC3
baculoviral IAP repeat containing 3
chr10_+_104154229 3.38 ENST00000428099.1
ENST00000369966.3
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr8_+_90769967 3.28 ENST00000220751.4
RIPK2
receptor-interacting serine-threonine kinase 2
chr6_+_32821924 3.21 ENST00000374859.2
ENST00000453265.2
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr5_-_146833222 3.16 ENST00000534907.1
DPYSL3
dihydropyrimidinase-like 3
chr11_+_19798964 2.88 ENST00000527559.2
NAV2
neuron navigator 2
chr9_-_32526184 2.86 ENST00000545044.1
ENST00000379868.1
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr17_+_40440481 2.82 ENST00000590726.2
ENST00000452307.2
ENST00000444283.1
ENST00000588868.1
STAT5A
signal transducer and activator of transcription 5A
chr12_-_57504069 2.67 ENST00000543873.2
ENST00000554663.1
ENST00000557635.1
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr9_-_136344197 2.66 ENST00000414172.1
ENST00000371897.4
SLC2A6
solute carrier family 2 (facilitated glucose transporter), member 6
chr11_+_19799327 2.64 ENST00000540292.1
NAV2
neuron navigator 2
chr6_+_132891461 2.40 ENST00000275198.1
TAAR6
trace amine associated receptor 6
chr21_+_34775698 2.27 ENST00000381995.1
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr4_-_185395672 2.27 ENST00000393593.3
IRF2
interferon regulatory factor 2
chr21_+_34775772 2.21 ENST00000405436.1
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr2_-_163175133 2.09 ENST00000421365.2
ENST00000263642.2
IFIH1
interferon induced with helicase C domain 1
chr18_-_71959159 2.01 ENST00000494131.2
ENST00000397914.4
ENST00000340533.4
CYB5A
cytochrome b5 type A (microsomal)
chr6_+_80341000 1.97 ENST00000369838.4
SH3BGRL2
SH3 domain binding glutamic acid-rich protein like 2
chr16_+_50730910 1.92 ENST00000300589.2
NOD2
nucleotide-binding oligomerization domain containing 2
chr2_+_68694678 1.80 ENST00000303795.4
APLF
aprataxin and PNKP like factor
chr8_+_54793454 1.62 ENST00000276500.4
RGS20
regulator of G-protein signaling 20
chr8_+_54793425 1.62 ENST00000522225.1
RGS20
regulator of G-protein signaling 20
chr14_+_103243813 1.58 ENST00000560371.1
ENST00000347662.4
ENST00000392745.2
ENST00000539721.1
ENST00000560463.1
TRAF3
TNF receptor-associated factor 3
chr22_-_19512893 1.52 ENST00000403084.1
ENST00000413119.2
CLDN5
claudin 5
chr10_+_13142075 1.52 ENST00000378757.2
ENST00000430081.1
ENST00000378752.3
ENST00000378748.3
OPTN
optineurin
chr5_-_146833485 1.49 ENST00000398514.3
DPYSL3
dihydropyrimidinase-like 3
chr2_+_32853093 1.49 ENST00000448773.1
ENST00000317907.4
TTC27
tetratricopeptide repeat domain 27
chr10_+_13142225 1.47 ENST00000378747.3
OPTN
optineurin
chr5_-_59189545 1.41 ENST00000340635.6
PDE4D
phosphodiesterase 4D, cAMP-specific
chr16_+_53738053 1.36 ENST00000394647.3
FTO
fat mass and obesity associated
chr21_+_34775181 1.34 ENST00000290219.6
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr16_-_2059748 1.34 ENST00000562103.1
ENST00000431526.1
ZNF598
zinc finger protein 598
chr21_-_16437126 1.33 ENST00000318948.4
NRIP1
nuclear receptor interacting protein 1
chr2_-_204400113 1.28 ENST00000319170.5
RAPH1
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
chr2_+_208394455 1.28 ENST00000430624.1
CREB1
cAMP responsive element binding protein 1
chr21_-_16437255 1.27 ENST00000400199.1
ENST00000400202.1
NRIP1
nuclear receptor interacting protein 1
chr10_+_13141585 1.24 ENST00000378764.2
OPTN
optineurin
chr11_-_65430554 1.23 ENST00000308639.9
ENST00000406246.3
RELA
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr4_+_74735102 1.21 ENST00000395761.3
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr9_+_72658490 1.19 ENST00000377182.4
MAMDC2
MAM domain containing 2
chr2_+_26568965 1.18 ENST00000260585.7
ENST00000447170.1
EPT1
ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)
chr3_+_182971018 1.16 ENST00000326505.3
B3GNT5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr1_-_160313025 1.15 ENST00000368069.3
ENST00000241704.7
COPA
coatomer protein complex, subunit alpha
chr4_-_74904398 1.11 ENST00000296026.4
CXCL3
chemokine (C-X-C motif) ligand 3
chr9_-_32526299 1.10 ENST00000379882.1
ENST00000379883.2
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr1_-_12677714 1.09 ENST00000376223.2
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr6_-_11779840 1.09 ENST00000506810.1
ADTRP
androgen-dependent TFPI-regulating protein
chr1_+_183441500 1.08 ENST00000456731.2
SMG7
SMG7 nonsense mediated mRNA decay factor
chr11_-_75062829 1.06 ENST00000393505.4
ARRB1
arrestin, beta 1
chr1_-_95392635 1.06 ENST00000538964.1
ENST00000394202.4
ENST00000370206.4
CNN3
calponin 3, acidic
chr19_-_17958832 1.05 ENST00000458235.1
JAK3
Janus kinase 3
chr10_-_75173785 1.05 ENST00000535178.1
ENST00000372921.5
ENST00000372919.4
ANXA7
annexin A7
chr17_-_7590745 1.04 ENST00000514944.1
ENST00000503591.1
ENST00000455263.2
ENST00000420246.2
ENST00000445888.2
ENST00000509690.1
ENST00000604348.1
ENST00000269305.4
TP53
tumor protein p53
chr10_-_96122682 1.01 ENST00000371361.3
NOC3L
nucleolar complex associated 3 homolog (S. cerevisiae)
chr15_-_77712477 1.01 ENST00000560626.2
PEAK1
pseudopodium-enriched atypical kinase 1
chr15_+_52311398 1.01 ENST00000261845.5
MAPK6
mitogen-activated protein kinase 6
chr3_-_47823298 0.98 ENST00000254480.5
SMARCC1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr11_-_75062730 0.95 ENST00000420843.2
ENST00000360025.3
ARRB1
arrestin, beta 1
chr8_+_38644715 0.93 ENST00000317827.4
ENST00000379931.3
TACC1
transforming, acidic coiled-coil containing protein 1
chr6_+_29910301 0.91 ENST00000376809.5
ENST00000376802.2
HLA-A
major histocompatibility complex, class I, A
chr10_+_12391481 0.91 ENST00000378847.3
CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr1_+_183441600 0.89 ENST00000367537.3
SMG7
SMG7 nonsense mediated mRNA decay factor
chr17_-_77005860 0.89 ENST00000591773.1
ENST00000588611.1
ENST00000586916.2
ENST00000592033.1
ENST00000588075.1
ENST00000302345.2
ENST00000591811.1
CANT1
calcium activated nucleotidase 1
chr10_+_114710425 0.86 ENST00000352065.5
ENST00000369395.1
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr12_-_54982300 0.84 ENST00000547431.1
PPP1R1A
protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr14_+_96858433 0.81 ENST00000267584.4
AK7
adenylate kinase 7
chrX_+_108779870 0.79 ENST00000372107.1
NXT2
nuclear transport factor 2-like export factor 2
chr1_+_110453514 0.79 ENST00000369802.3
ENST00000420111.2
CSF1
colony stimulating factor 1 (macrophage)
chr2_+_232646379 0.78 ENST00000410024.1
ENST00000409295.1
ENST00000409091.1
COPS7B
COP9 signalosome subunit 7B
chr1_-_247242048 0.78 ENST00000366503.2
ZNF670
zinc finger protein 670
chr17_-_77005801 0.76 ENST00000392446.5
CANT1
calcium activated nucleotidase 1
chr22_-_37640456 0.76 ENST00000405484.1
ENST00000441619.1
ENST00000406508.1
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr8_-_101962777 0.74 ENST00000395951.3
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr6_-_36355513 0.73 ENST00000340181.4
ENST00000373737.4
ETV7
ets variant 7
chr20_-_18477862 0.73 ENST00000337227.4
RBBP9
retinoblastoma binding protein 9
chr16_+_57392684 0.72 ENST00000219235.4
CCL22
chemokine (C-C motif) ligand 22
chr15_-_101817616 0.72 ENST00000526049.1
ENST00000398226.3
ENST00000537379.1
VIMP
VCP-interacting membrane protein
chr10_-_73975657 0.71 ENST00000394919.1
ENST00000526751.1
ASCC1
activating signal cointegrator 1 complex subunit 1
chr10_+_77056134 0.70 ENST00000528121.1
ENST00000416398.1
ZNF503-AS1
ZNF503 antisense RNA 1
chrX_+_108780347 0.70 ENST00000372103.1
NXT2
nuclear transport factor 2-like export factor 2
chr19_+_39390320 0.67 ENST00000576510.1
NFKBIB
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr4_-_52904425 0.67 ENST00000535450.1
SGCB
sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
chr3_+_140770183 0.67 ENST00000310546.2
SPSB4
splA/ryanodine receptor domain and SOCS box containing 4
chr6_+_15401075 0.66 ENST00000541660.1
JARID2
jumonji, AT rich interactive domain 2
chr2_-_100721923 0.66 ENST00000356421.2
AFF3
AF4/FMR2 family, member 3
chr11_+_74951948 0.65 ENST00000562197.2
TPBGL
trophoblast glycoprotein-like
chr10_-_73976025 0.65 ENST00000342444.4
ENST00000533958.1
ENST00000527593.1
ENST00000394915.3
ENST00000530461.1
ENST00000317168.6
ENST00000524829.1
ASCC1
activating signal cointegrator 1 complex subunit 1
chr11_-_3862206 0.65 ENST00000351018.4
RHOG
ras homolog family member G
chr7_+_86273218 0.64 ENST00000361669.2
GRM3
glutamate receptor, metabotropic 3
chr4_+_4861385 0.64 ENST00000382723.4
MSX1
msh homeobox 1
chr4_+_39046615 0.62 ENST00000261425.3
ENST00000508137.2
KLHL5
kelch-like family member 5
chr15_+_85923797 0.61 ENST00000559362.1
AKAP13
A kinase (PRKA) anchor protein 13
chr4_-_79860506 0.61 ENST00000295462.3
ENST00000380645.4
ENST00000512733.1
PAQR3
progestin and adipoQ receptor family member III
chr16_-_15188106 0.61 ENST00000429751.2
ENST00000564131.1
ENST00000563559.1
ENST00000198767.6
RRN3
RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
chr16_-_2059797 0.60 ENST00000563630.1
ZNF598
zinc finger protein 598
chr19_+_39390587 0.60 ENST00000572515.1
ENST00000392079.3
ENST00000575359.1
ENST00000313582.5
NFKBIB
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr6_-_35656685 0.58 ENST00000539068.1
ENST00000540787.1
FKBP5
FK506 binding protein 5
chr14_-_106967788 0.58 ENST00000390622.2
IGHV1-46
immunoglobulin heavy variable 1-46
chr17_-_40828969 0.58 ENST00000591022.1
ENST00000587627.1
ENST00000293349.6
PLEKHH3
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr3_+_184032313 0.57 ENST00000392537.2
ENST00000444134.1
ENST00000450424.1
ENST00000421110.1
ENST00000382330.3
ENST00000426123.1
ENST00000350481.5
ENST00000455679.1
ENST00000440448.1
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr12_-_127256858 0.57 ENST00000542248.1
ENST00000540684.1
LINC00944
long intergenic non-protein coding RNA 944
chr7_-_22539771 0.57 ENST00000406890.2
ENST00000424363.1
STEAP1B
STEAP family member 1B
chrX_-_65253506 0.56 ENST00000427538.1
VSIG4
V-set and immunoglobulin domain containing 4
chr1_+_24117693 0.56 ENST00000374503.3
ENST00000374502.3
LYPLA2
lysophospholipase II
chr5_+_67584174 0.56 ENST00000320694.8
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr12_+_6309517 0.56 ENST00000382519.4
ENST00000009180.4
CD9
CD9 molecule
chr7_-_69062391 0.56 ENST00000436600.2
RP5-942I16.1
RP5-942I16.1
chr14_-_35873856 0.55 ENST00000553342.1
ENST00000216797.5
ENST00000557140.1
NFKBIA
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr21_-_43373999 0.54 ENST00000380486.3
C2CD2
C2 calcium-dependent domain containing 2
chr11_+_64052266 0.54 ENST00000539851.1
GPR137
G protein-coupled receptor 137
chr1_+_37940153 0.53 ENST00000373087.6
ZC3H12A
zinc finger CCCH-type containing 12A
chr1_+_6845384 0.53 ENST00000303635.7
CAMTA1
calmodulin binding transcription activator 1
chr3_+_1134260 0.52 ENST00000446702.2
ENST00000539053.1
ENST00000350110.2
CNTN6
contactin 6
chr2_+_114163945 0.52 ENST00000453673.3
IGKV1OR2-108
immunoglobulin kappa variable 1/OR2-108 (non-functional)
chr12_-_53074182 0.52 ENST00000252244.3
KRT1
keratin 1
chr16_+_3014217 0.51 ENST00000572045.1
KREMEN2
kringle containing transmembrane protein 2
chr4_+_140222609 0.49 ENST00000296543.5
ENST00000398947.1
NAA15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr4_-_74964904 0.49 ENST00000508487.2
CXCL2
chemokine (C-X-C motif) ligand 2
chr12_+_6308881 0.49 ENST00000382518.1
ENST00000536586.1
CD9
CD9 molecule
chr11_+_64052692 0.49 ENST00000377702.4
GPR137
G protein-coupled receptor 137
chr1_+_75594119 0.49 ENST00000294638.5
LHX8
LIM homeobox 8
chr11_+_64052294 0.49 ENST00000536667.1
GPR137
G protein-coupled receptor 137
chr7_+_6048856 0.48 ENST00000223029.3
ENST00000400479.2
ENST00000395236.2
AIMP2
aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
chr6_+_36164487 0.48 ENST00000357641.6
BRPF3
bromodomain and PHD finger containing, 3
chrX_+_15518923 0.48 ENST00000348343.6
BMX
BMX non-receptor tyrosine kinase
chr5_+_134181625 0.47 ENST00000394976.3
C5orf24
chromosome 5 open reading frame 24
chr11_+_5423827 0.47 ENST00000332043.1
OR51J1
olfactory receptor, family 51, subfamily J, member 1 (gene/pseudogene)
chr20_-_2451395 0.46 ENST00000339610.6
ENST00000381342.2
ENST00000438552.2
SNRPB
small nuclear ribonucleoprotein polypeptides B and B1
chr14_+_29234870 0.45 ENST00000382535.3
FOXG1
forkhead box G1
chr17_-_7141490 0.45 ENST00000574236.1
ENST00000572789.1
PHF23
PHD finger protein 23
chr11_+_64052454 0.44 ENST00000539833.1
GPR137
G protein-coupled receptor 137
chr3_+_184032419 0.44 ENST00000352767.3
ENST00000427141.2
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr1_-_205904950 0.43 ENST00000340781.4
SLC26A9
solute carrier family 26 (anion exchanger), member 9
chr16_+_2563871 0.43 ENST00000330398.4
ENST00000568562.1
ENST00000569317.1
ATP6V0C
ATP6C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
Uncharacterized protein
chr17_+_40985407 0.42 ENST00000586114.1
ENST00000590720.1
ENST00000585805.1
ENST00000541124.1
ENST00000441946.2
ENST00000591152.1
ENST00000589469.1
ENST00000293362.3
ENST00000592169.1
PSME3
proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr8_+_55528627 0.42 ENST00000220676.1
RP1
retinitis pigmentosa 1 (autosomal dominant)
chr10_+_86088381 0.41 ENST00000224756.8
ENST00000372088.2
CCSER2
coiled-coil serine-rich protein 2
chr2_-_27718052 0.41 ENST00000264703.3
FNDC4
fibronectin type III domain containing 4
chr12_-_56221330 0.39 ENST00000546837.1
RP11-762I7.5
Uncharacterized protein
chrX_+_103031421 0.39 ENST00000433491.1
ENST00000418604.1
ENST00000443502.1
PLP1
proteolipid protein 1
chr8_+_101170563 0.39 ENST00000520508.1
ENST00000388798.2
SPAG1
sperm associated antigen 1
chr3_+_184032283 0.39 ENST00000346169.2
ENST00000414031.1
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr1_-_6321035 0.39 ENST00000377893.2
GPR153
G protein-coupled receptor 153
chr3_+_148415571 0.38 ENST00000497524.1
ENST00000349243.3
ENST00000542281.1
ENST00000418473.2
ENST00000404754.2
AGTR1
angiotensin II receptor, type 1
chr2_+_64681103 0.38 ENST00000464281.1
LGALSL
lectin, galactoside-binding-like
chr12_-_125473600 0.38 ENST00000308736.2
DHX37
DEAH (Asp-Glu-Ala-His) box polypeptide 37
chr3_-_107941230 0.38 ENST00000264538.3
IFT57
intraflagellar transport 57 homolog (Chlamydomonas)
chr3_+_42201653 0.38 ENST00000341421.3
ENST00000396175.1
TRAK1
trafficking protein, kinesin binding 1
chr5_-_132073111 0.37 ENST00000403231.1
KIF3A
kinesin family member 3A
chr17_+_65373531 0.37 ENST00000580974.1
PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr7_+_103969104 0.36 ENST00000424859.1
ENST00000535008.1
ENST00000401970.2
ENST00000543266.1
LHFPL3
lipoma HMGIC fusion partner-like 3
chr4_-_76928641 0.36 ENST00000264888.5
CXCL9
chemokine (C-X-C motif) ligand 9
chr20_+_9494987 0.36 ENST00000427562.2
ENST00000246070.2
LAMP5
lysosomal-associated membrane protein family, member 5
chrX_+_108780062 0.36 ENST00000372106.1
NXT2
nuclear transport factor 2-like export factor 2
chr6_+_42018614 0.36 ENST00000465926.1
ENST00000482432.1
TAF8
TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
chr17_-_40540484 0.36 ENST00000588969.1
STAT3
signal transducer and activator of transcription 3 (acute-phase response factor)
chr1_+_180165672 0.36 ENST00000443059.1
QSOX1
quiescin Q6 sulfhydryl oxidase 1
chr1_-_75139397 0.35 ENST00000326665.5
C1orf173
chromosome 1 open reading frame 173
chr2_+_159825143 0.35 ENST00000454300.1
ENST00000263635.6
TANC1
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chr6_-_24358264 0.34 ENST00000378454.3
DCDC2
doublecortin domain containing 2
chr10_+_30722866 0.33 ENST00000263056.1
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr12_-_108991812 0.33 ENST00000392806.3
ENST00000547567.1
TMEM119
transmembrane protein 119
chr12_-_31945172 0.33 ENST00000340398.3
H3F3C
H3 histone, family 3C
chr20_-_4795747 0.33 ENST00000379376.2
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr16_+_29819096 0.33 ENST00000568411.1
ENST00000563012.1
ENST00000562557.1
MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr6_-_7389942 0.32 ENST00000296742.7
ENST00000502583.1
CAGE1
cancer antigen 1
chr19_-_4065730 0.32 ENST00000601588.1
ZBTB7A
zinc finger and BTB domain containing 7A
chr3_-_194072019 0.32 ENST00000429275.1
ENST00000323830.3
CPN2
carboxypeptidase N, polypeptide 2
chr17_-_40829026 0.31 ENST00000412503.1
PLEKHH3
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr1_+_94884023 0.31 ENST00000315713.5
ABCD3
ATP-binding cassette, sub-family D (ALD), member 3
chr16_-_67978016 0.31 ENST00000264005.5
LCAT
lecithin-cholesterol acyltransferase
chr9_-_130693048 0.30 ENST00000388747.4
PIP5KL1
phosphatidylinositol-4-phosphate 5-kinase-like 1
chr10_+_89419370 0.30 ENST00000361175.4
ENST00000456849.1
PAPSS2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr22_+_22786288 0.30 ENST00000390301.2
IGLV1-36
immunoglobulin lambda variable 1-36
chrX_+_16737718 0.29 ENST00000380155.3
SYAP1
synapse associated protein 1
chr1_-_202129704 0.28 ENST00000476061.1
ENST00000544762.1
ENST00000467283.1
ENST00000464870.1
ENST00000435759.2
ENST00000486116.1
ENST00000543735.1
ENST00000308986.5
ENST00000477625.1
PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr3_-_155572164 0.28 ENST00000392845.3
ENST00000359479.3
SLC33A1
solute carrier family 33 (acetyl-CoA transporter), member 1
chrX_-_131352152 0.28 ENST00000342983.2
RAP2C
RAP2C, member of RAS oncogene family
chr4_+_185395947 0.27 ENST00000605834.1
RP11-326I11.3
RP11-326I11.3
chr18_-_70535177 0.27 ENST00000327305.6
NETO1
neuropilin (NRP) and tolloid (TLL)-like 1
chr1_-_113249734 0.27 ENST00000484054.3
ENST00000369636.2
ENST00000369637.1
ENST00000285735.2
ENST00000369638.2
RHOC
ras homolog family member C

Network of associatons between targets according to the STRING database.

First level regulatory network of RELB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 13.5 GO:1904141 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
1.9 1.9 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
1.9 11.4 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
1.8 9.2 GO:0070842 aggresome assembly(GO:0070842)
1.8 7.3 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
1.7 6.6 GO:2000329 negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
1.5 6.1 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.9 3.7 GO:0046967 cytosol to ER transport(GO:0046967)
0.8 3.4 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.8 5.8 GO:2000630 positive regulation of miRNA metabolic process(GO:2000630)
0.8 7.1 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.7 2.8 GO:0000255 allantoin metabolic process(GO:0000255)
0.7 5.5 GO:0021564 vagus nerve development(GO:0021564)
0.7 2.7 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.7 3.9 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
0.5 1.0 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
0.5 14.9 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.5 1.9 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.5 4.2 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.5 1.4 GO:0035552 oxidative single-stranded DNA demethylation(GO:0035552)
0.3 1.0 GO:0002730 regulation of dendritic cell cytokine production(GO:0002730)
0.3 0.8 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.3 4.9 GO:0051601 exocyst localization(GO:0051601)
0.3 1.6 GO:0008063 Toll signaling pathway(GO:0008063)
0.2 3.6 GO:0016322 neuron remodeling(GO:0016322)
0.2 1.8 GO:0051106 positive regulation of DNA ligation(GO:0051106)
0.2 1.3 GO:0034670 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.2 0.6 GO:0090427 activation of meiosis(GO:0090427)
0.2 2.8 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.2 1.5 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.2 2.6 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.2 2.0 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.2 3.9 GO:0051764 actin crosslink formation(GO:0051764)
0.2 0.5 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.2 1.4 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.2 0.9 GO:0044334 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.2 0.3 GO:0090107 regulation of high-density lipoprotein particle assembly(GO:0090107)
0.1 0.6 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.1 1.4 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.1 4.8 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.1 1.4 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.1 2.0 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.1 0.3 GO:0043132 coenzyme A transport(GO:0015880) FAD transport(GO:0015883) coenzyme A transmembrane transport(GO:0035349) FAD transmembrane transport(GO:0035350) NAD transport(GO:0043132) adenosine 3',5'-bisphosphate transmembrane transport(GO:0071106) AMP transport(GO:0080121)
0.1 0.4 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1 0.3 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1 0.9 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.1 0.5 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 1.0 GO:0009414 response to water deprivation(GO:0009414)
0.1 0.6 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.1 0.3 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560) negative regulation of beta-amyloid clearance(GO:1900222)
0.1 0.3 GO:0030451 regulation of complement activation, alternative pathway(GO:0030451) negative regulation of complement activation, alternative pathway(GO:0045957)
0.1 0.5 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 2.7 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.1 0.6 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 1.1 GO:0030157 pancreatic juice secretion(GO:0030157)
0.1 0.3 GO:0000103 sulfate assimilation(GO:0000103)
0.1 1.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.5 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.5 GO:0002084 protein depalmitoylation(GO:0002084)
0.1 0.3 GO:0051182 coenzyme transport(GO:0051182)
0.1 0.3 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
0.1 0.2 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.1 0.2 GO:0045357 interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.1 0.2 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.1 0.2 GO:2000213 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.1 0.2 GO:0016999 antibiotic metabolic process(GO:0016999) cellular amide catabolic process(GO:0043605)
0.1 1.1 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 0.3 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 0.2 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.1 0.7 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.0 0.7 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.2 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.5 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.1 GO:0016115 terpenoid catabolic process(GO:0016115)
0.0 0.8 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.5 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.6 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.4 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.2 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.5 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.0 0.4 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 0.7 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574) negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0 0.4 GO:0046549 photoreceptor cell outer segment organization(GO:0035845) retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 3.7 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.0 1.1 GO:0009651 response to salt stress(GO:0009651)
0.0 0.1 GO:0098528 skeletal muscle fiber differentiation(GO:0098528) negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.4 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.0 0.3 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.2 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.0 0.2 GO:0015853 adenine transport(GO:0015853)
0.0 0.2 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 0.1 GO:0048850 hypophysis morphogenesis(GO:0048850)
0.0 0.6 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.0 0.6 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:2000196 positive regulation of female gonad development(GO:2000196)
0.0 0.2 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.0 0.3 GO:1903012 positive regulation of bone development(GO:1903012)
0.0 0.4 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.7 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 1.7 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.0 0.3 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.1 GO:0060022 hard palate development(GO:0060022)
0.0 0.4 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 3.7 GO:0051028 mRNA transport(GO:0051028)
0.0 0.1 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130) neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) neutrophil mediated killing of bacterium(GO:0070944)
0.0 0.6 GO:0090004 positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.0 0.6 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.0 0.2 GO:0042048 olfactory behavior(GO:0042048)
0.0 0.5 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 1.2 GO:0009247 glycolipid biosynthetic process(GO:0009247)
0.0 0.2 GO:0048102 autophagic cell death(GO:0048102)
0.0 0.4 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.2 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 2.3 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.2 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.3 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 1.5 GO:0030449 regulation of complement activation(GO:0030449)
0.0 0.4 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.1 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.0 0.9 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.2 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.3 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.4 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.0 0.6 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 13.5 GO:1990682 CSF1-CSF1R complex(GO:1990682)
1.0 12.0 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.5 3.7 GO:0042825 TAP complex(GO:0042825)
0.4 3.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.2 5.5 GO:0005614 interstitial matrix(GO:0005614)
0.2 1.3 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.2 0.9 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 0.6 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 4.9 GO:0000145 exocyst(GO:0000145)
0.1 8.9 GO:0016235 aggresome(GO:0016235)
0.1 0.5 GO:0016939 kinesin II complex(GO:0016939)
0.1 1.5 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 1.1 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 0.5 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 0.9 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.5 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.7 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 1.0 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 0.4 GO:0008537 proteasome activator complex(GO:0008537)
0.1 1.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.5 GO:0031415 NatA complex(GO:0031415)
0.1 1.1 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 3.9 GO:0031941 filamentous actin(GO:0031941)
0.1 0.4 GO:0032584 growth cone membrane(GO:0032584)
0.1 0.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.5 GO:0005683 U7 snRNP(GO:0005683) histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.4 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 1.0 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 1.3 GO:0031143 pseudopodium(GO:0031143)
0.0 1.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 3.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.8 GO:0035861 site of double-strand break(GO:0035861)
0.0 1.0 GO:0001741 XY body(GO:0001741)
0.0 2.6 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.2 GO:0097342 ripoptosome(GO:0097342)
0.0 0.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.4 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 1.0 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.3 GO:0060091 kinocilium(GO:0060091)
0.0 0.3 GO:0000801 central element(GO:0000801)
0.0 3.9 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.3 GO:0044292 dendrite terminus(GO:0044292)
0.0 0.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.3 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0016938 kinesin I complex(GO:0016938)
0.0 0.1 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 1.1 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.1 GO:0032010 phagolysosome(GO:0032010)
0.0 0.5 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.1 GO:0002081 outer acrosomal membrane(GO:0002081)
0.0 1.0 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.6 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.1 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.0 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 1.1 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.8 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 21.3 GO:0005615 extracellular space(GO:0005615)
0.0 0.9 GO:0030175 filopodium(GO:0030175)
0.0 0.5 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 3.7 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 13.5 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
1.2 5.8 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.9 13.9 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.7 2.0 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.6 7.1 GO:0030274 LIM domain binding(GO:0030274)
0.6 1.7 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.5 3.7 GO:0046979 TAP2 binding(GO:0046979)
0.5 1.4 GO:0035514 DNA demethylase activity(GO:0035514)
0.4 9.2 GO:0070628 proteasome binding(GO:0070628)
0.4 2.4 GO:0001594 trace-amine receptor activity(GO:0001594)
0.4 4.7 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.4 1.2 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.3 14.3 GO:0031593 polyubiquitin binding(GO:0031593)
0.2 0.6 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.2 2.7 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.2 1.3 GO:1990763 arrestin family protein binding(GO:1990763)
0.2 7.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 1.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 1.0 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.1 0.6 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.1 3.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.4 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 0.9 GO:0004127 cytidylate kinase activity(GO:0004127)
0.1 1.9 GO:0042834 peptidoglycan binding(GO:0042834)
0.1 3.9 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 3.2 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.3 GO:0004779 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1 0.3 GO:0071077 coenzyme A transmembrane transporter activity(GO:0015228) FAD transmembrane transporter activity(GO:0015230) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.1 1.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 1.6 GO:0031996 thioesterase binding(GO:0031996)
0.1 0.3 GO:0051185 coenzyme transporter activity(GO:0051185)
0.1 0.3 GO:0004877 complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
0.1 1.8 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.1 0.5 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.1 2.2 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.1 0.3 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.1 0.3 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.1 1.4 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 1.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.4 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 0.6 GO:0043559 insulin binding(GO:0043559)
0.1 0.9 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.2 GO:0017130 poly(C) RNA binding(GO:0017130)
0.1 0.9 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.2 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.1 0.4 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 1.0 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 0.2 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.1 0.2 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.1 2.6 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.5 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.5 GO:0035198 miRNA binding(GO:0035198)
0.0 2.0 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 6.0 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 3.2 GO:0032813 tumor necrosis factor receptor superfamily binding(GO:0032813)
0.0 0.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.8 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.2 GO:0015207 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.0 0.3 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 1.0 GO:0004707 MAP kinase activity(GO:0004707)
0.0 1.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.2 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 1.1 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.1 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.0 0.5 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.3 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 2.4 GO:0043022 ribosome binding(GO:0043022)
0.0 0.2 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 2.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 5.4 GO:0008201 heparin binding(GO:0008201)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.7 GO:0008009 chemokine activity(GO:0008009)
0.0 4.2 GO:0000149 SNARE binding(GO:0000149)
0.0 0.3 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.3 GO:0000150 recombinase activity(GO:0000150)
0.0 0.5 GO:0005112 Notch binding(GO:0005112)
0.0 2.5 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 0.2 GO:0031433 telethonin binding(GO:0031433)
0.0 1.0 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.6 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 5.7 GO:0003924 GTPase activity(GO:0003924)
0.0 0.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.1 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.9 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 13.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.4 18.6 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.3 0.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.3 12.4 PID CD40 PATHWAY CD40/CD40L signaling
0.1 5.2 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.1 4.7 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 7.6 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 3.0 ST G ALPHA I PATHWAY G alpha i Pathway
0.1 2.6 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 1.8 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 3.2 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 1.8 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.1 PID ARF 3PATHWAY Arf1 pathway
0.0 2.0 PID AURORA A PATHWAY Aurora A signaling
0.0 14.8 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 1.8 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.6 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.8 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.9 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 2.9 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.9 PID AP1 PATHWAY AP-1 transcription factor network
0.0 1.5 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.6 PID MTOR 4PATHWAY mTOR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 8.8 REACTOME P75NTR SIGNALS VIA NFKB Genes involved in p75NTR signals via NF-kB
0.4 7.6 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.3 4.7 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.3 12.7 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.2 4.7 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.2 14.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.2 4.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 0.2 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.2 3.7 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2 3.8 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 4.6 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 2.7 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 2.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 1.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 1.4 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 4.2 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.1 1.4 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 2.0 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 2.1 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 3.2 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.2 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 1.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.3 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.7 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.6 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 3.2 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.5 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.2 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 2.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.9 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.9 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.5 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules