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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for RORA

Z-value: 0.70

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Transcription factors associated with RORA

Gene Symbol Gene ID Gene Info
RORA
ENSG00000069667.11 RAR related orphan receptor A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RORAhg19_v2_chr15_-_61521495_615215180.527.9e-03Click!

Activity profile of RORA motif

Sorted Z-values of RORA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_93963590 2.52 ENST00000340600.2
SOCS2
suppressor of cytokine signaling 2
chr12_+_93964158 2.42 ENST00000549206.1
SOCS2
suppressor of cytokine signaling 2
chr3_+_46448648 1.58 ENST00000399036.3
CCRL2
chemokine (C-C motif) receptor-like 2
chr3_+_46449049 1.53 ENST00000357392.4
ENST00000400880.3
ENST00000433848.1
CCRL2
chemokine (C-C motif) receptor-like 2
chr3_+_141105235 1.40 ENST00000503809.1
ZBTB38
zinc finger and BTB domain containing 38
chr4_-_186732048 1.34 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
SORBS2
sorbin and SH3 domain containing 2
chr3_-_18480260 0.95 ENST00000454909.2
SATB1
SATB homeobox 1
chr19_+_45251804 0.93 ENST00000164227.5
BCL3
B-cell CLL/lymphoma 3
chr2_+_162016827 0.84 ENST00000429217.1
ENST00000406287.1
ENST00000402568.1
TANK
TRAF family member-associated NFKB activator
chrX_+_10124977 0.75 ENST00000380833.4
CLCN4
chloride channel, voltage-sensitive 4
chr10_-_65028817 0.73 ENST00000542921.1
JMJD1C
jumonji domain containing 1C
chr19_-_49552006 0.66 ENST00000391869.3
CGB1
chorionic gonadotropin, beta polypeptide 1
chr1_-_211752073 0.63 ENST00000367001.4
SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr22_-_38699003 0.60 ENST00000451964.1
CSNK1E
casein kinase 1, epsilon
chr10_+_112257596 0.59 ENST00000369583.3
DUSP5
dual specificity phosphatase 5
chr2_+_162016804 0.58 ENST00000392749.2
ENST00000440506.1
TANK
TRAF family member-associated NFKB activator
chr2_+_109237717 0.57 ENST00000409441.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr2_-_177502659 0.54 ENST00000295549.4
AC017048.3
long intergenic non-protein coding RNA 1116
chr2_+_162016916 0.54 ENST00000405852.1
TANK
TRAF family member-associated NFKB activator
chr10_+_77056134 0.52 ENST00000528121.1
ENST00000416398.1
ZNF503-AS1
ZNF503 antisense RNA 1
chr7_+_128399002 0.49 ENST00000493278.1
CALU
calumenin
chr5_+_73109339 0.48 ENST00000296799.4
ARHGEF28
Rho guanine nucleotide exchange factor (GEF) 28
chr11_+_64879317 0.48 ENST00000526809.1
ENST00000279263.7
ENST00000524986.1
ENST00000534371.1
ENST00000540748.1
ENST00000525385.1
ENST00000345348.5
ENST00000531321.1
ENST00000529414.1
ENST00000526085.1
ENST00000530750.1
TM7SF2
transmembrane 7 superfamily member 2
chrX_-_129299638 0.43 ENST00000535724.1
ENST00000346424.2
AIFM1
apoptosis-inducing factor, mitochondrion-associated, 1
chr19_-_39826639 0.43 ENST00000602185.1
ENST00000598034.1
ENST00000601387.1
ENST00000595636.1
ENST00000253054.8
ENST00000594700.1
ENST00000597595.1
GMFG
glia maturation factor, gamma
chr16_-_49698136 0.43 ENST00000535559.1
ZNF423
zinc finger protein 423
chr6_-_111927062 0.41 ENST00000359831.4
TRAF3IP2
TRAF3 interacting protein 2
chr6_-_107077347 0.40 ENST00000369063.3
ENST00000539449.1
RTN4IP1
reticulon 4 interacting protein 1
chr16_+_82090028 0.37 ENST00000568090.1
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr1_-_91487770 0.36 ENST00000337393.5
ZNF644
zinc finger protein 644
chr5_-_137071756 0.35 ENST00000394937.3
ENST00000309755.4
KLHL3
kelch-like family member 3
chr1_+_29213678 0.34 ENST00000347529.3
EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr1_+_212738676 0.34 ENST00000366981.4
ENST00000366987.2
ATF3
activating transcription factor 3
chr19_+_46850251 0.33 ENST00000012443.4
PPP5C
protein phosphatase 5, catalytic subunit
chr16_-_28303360 0.32 ENST00000501520.1
RP11-57A19.2
RP11-57A19.2
chr19_-_50311896 0.32 ENST00000529634.2
FUZ
fuzzy planar cell polarity protein
chr3_-_183735731 0.32 ENST00000334444.6
ABCC5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr17_+_2699697 0.31 ENST00000254695.8
ENST00000366401.4
ENST00000542807.1
RAP1GAP2
RAP1 GTPase activating protein 2
chr19_-_49140609 0.31 ENST00000601104.1
DBP
D site of albumin promoter (albumin D-box) binding protein
chr10_-_65028938 0.30 ENST00000402544.1
JMJD1C
jumonji domain containing 1C
chr2_-_209118974 0.30 ENST00000415913.1
ENST00000415282.1
ENST00000446179.1
IDH1
isocitrate dehydrogenase 1 (NADP+), soluble
chr19_+_46850320 0.29 ENST00000391919.1
PPP5C
protein phosphatase 5, catalytic subunit
chr11_+_128563652 0.28 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr10_+_76586348 0.28 ENST00000372724.1
ENST00000287239.4
ENST00000372714.1
KAT6B
K(lysine) acetyltransferase 6B
chr7_-_128415844 0.28 ENST00000249389.2
OPN1SW
opsin 1 (cone pigments), short-wave-sensitive
chrX_+_16737718 0.28 ENST00000380155.3
SYAP1
synapse associated protein 1
chr7_+_129007964 0.28 ENST00000460109.1
ENST00000474594.1
ENST00000446212.1
AHCYL2
adenosylhomocysteinase-like 2
chr7_-_107642348 0.27 ENST00000393561.1
LAMB1
laminin, beta 1
chr22_-_24110063 0.27 ENST00000520222.1
ENST00000401675.3
CHCHD10
coiled-coil-helix-coiled-coil-helix domain containing 10
chr16_+_31366455 0.27 ENST00000268296.4
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr21_+_17553910 0.27 ENST00000428669.2
LINC00478
long intergenic non-protein coding RNA 478
chr1_+_229440129 0.26 ENST00000366688.3
SPHAR
S-phase response (cyclin related)
chr3_-_183735651 0.25 ENST00000427120.2
ENST00000392579.2
ENST00000382494.2
ENST00000446941.2
ABCC5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr11_+_76571911 0.25 ENST00000534206.1
ENST00000532485.1
ENST00000526597.1
ENST00000533873.1
ENST00000538157.1
ACER3
alkaline ceramidase 3
chr6_+_36839616 0.25 ENST00000359359.2
ENST00000510325.2
C6orf89
chromosome 6 open reading frame 89
chr15_-_44486632 0.24 ENST00000484674.1
FRMD5
FERM domain containing 5
chr7_+_112063192 0.24 ENST00000005558.4
IFRD1
interferon-related developmental regulator 1
chr3_-_141747950 0.23 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr10_-_103578182 0.23 ENST00000439817.1
MGEA5
meningioma expressed antigen 5 (hyaluronidase)
chr16_-_88717423 0.23 ENST00000568278.1
ENST00000569359.1
ENST00000567174.1
CYBA
cytochrome b-245, alpha polypeptide
chr16_+_31366536 0.23 ENST00000562522.1
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr16_-_47177874 0.22 ENST00000562435.1
NETO2
neuropilin (NRP) and tolloid (TLL)-like 2
chr3_+_52813932 0.22 ENST00000537050.1
ITIH1
inter-alpha-trypsin inhibitor heavy chain 1
chrX_-_71526999 0.22 ENST00000453707.2
ENST00000373619.3
CITED1
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr16_+_28303804 0.21 ENST00000341901.4
SBK1
SH3 domain binding kinase 1
chr6_-_41039567 0.21 ENST00000468811.1
OARD1
O-acyl-ADP-ribose deacylase 1
chr12_+_120875910 0.20 ENST00000551806.1
AL021546.6
Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial
chr3_-_27498235 0.19 ENST00000295736.5
ENST00000428386.1
ENST00000428179.1
SLC4A7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr18_-_19284724 0.19 ENST00000580981.1
ENST00000289119.2
ABHD3
abhydrolase domain containing 3
chr6_+_53948328 0.19 ENST00000370876.2
MLIP
muscular LMNA-interacting protein
chr5_-_137071689 0.19 ENST00000505853.1
KLHL3
kelch-like family member 3
chr8_+_37553261 0.18 ENST00000331569.4
ZNF703
zinc finger protein 703
chr17_+_74075263 0.18 ENST00000334586.5
ENST00000392503.2
ZACN
zinc activated ligand-gated ion channel
chr7_-_123197733 0.17 ENST00000470123.1
ENST00000471770.1
NDUFA5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr2_+_134877740 0.17 ENST00000409645.1
MGAT5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr18_-_56296182 0.17 ENST00000361673.3
ALPK2
alpha-kinase 2
chr17_+_42148225 0.17 ENST00000591696.1
G6PC3
glucose 6 phosphatase, catalytic, 3
chr15_-_44487408 0.17 ENST00000402883.1
ENST00000417257.1
FRMD5
FERM domain containing 5
chr5_+_140027355 0.17 ENST00000417647.2
ENST00000507593.1
ENST00000508301.1
IK
IK cytokine, down-regulator of HLA II
chr17_-_27503770 0.16 ENST00000533112.1
MYO18A
myosin XVIIIA
chr3_-_113464906 0.16 ENST00000477813.1
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr6_+_44126545 0.16 ENST00000532171.1
ENST00000398776.1
ENST00000542245.1
CAPN11
calpain 11
chr20_+_49126881 0.16 ENST00000371621.3
ENST00000541713.1
PTPN1
protein tyrosine phosphatase, non-receptor type 1
chr19_-_11689752 0.16 ENST00000592659.1
ENST00000592828.1
ENST00000218758.5
ENST00000412435.2
ACP5
acid phosphatase 5, tartrate resistant
chr17_-_46716647 0.16 ENST00000608940.1
RP11-357H14.17
RP11-357H14.17
chr9_-_39239171 0.16 ENST00000358144.2
CNTNAP3
contactin associated protein-like 3
chr11_+_66624527 0.16 ENST00000393952.3
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr11_+_111957497 0.15 ENST00000375549.3
ENST00000528182.1
ENST00000528048.1
ENST00000528021.1
ENST00000526592.1
ENST00000525291.1
SDHD
succinate dehydrogenase complex, subunit D, integral membrane protein
chr12_+_72080253 0.15 ENST00000549735.1
TMEM19
transmembrane protein 19
chr19_+_16059818 0.15 ENST00000322107.1
OR10H4
olfactory receptor, family 10, subfamily H, member 4
chr19_+_7011509 0.14 ENST00000377296.3
AC025278.1
Uncharacterized protein
chr5_+_132208014 0.14 ENST00000296877.2
LEAP2
liver expressed antimicrobial peptide 2
chr3_+_179322573 0.14 ENST00000493866.1
ENST00000472629.1
ENST00000482604.1
NDUFB5
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
chr16_+_777118 0.14 ENST00000562141.1
HAGHL
hydroxyacylglutathione hydrolase-like
chr16_-_18812746 0.14 ENST00000546206.2
ENST00000562819.1
ENST00000562234.2
ENST00000304414.7
ENST00000567078.2
ARL6IP1
RP11-1035H13.3
ADP-ribosylation factor-like 6 interacting protein 1
Uncharacterized protein
chr10_-_103578162 0.14 ENST00000361464.3
ENST00000357797.5
ENST00000370094.3
MGEA5
meningioma expressed antigen 5 (hyaluronidase)
chr15_+_76352178 0.13 ENST00000388942.3
C15orf27
chromosome 15 open reading frame 27
chr3_+_113465866 0.13 ENST00000273398.3
ENST00000538620.1
ENST00000496747.1
ENST00000475322.1
ATP6V1A
ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr16_+_21964662 0.13 ENST00000561553.1
ENST00000565331.1
UQCRC2
ubiquinol-cytochrome c reductase core protein II
chr12_-_58135903 0.13 ENST00000257897.3
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr21_-_46330545 0.13 ENST00000320216.6
ENST00000397852.1
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr7_-_43965937 0.13 ENST00000455877.1
ENST00000223341.7
ENST00000447717.3
ENST00000426198.1
URGCP
upregulator of cell proliferation
chr19_+_54606145 0.12 ENST00000485876.1
ENST00000391762.1
ENST00000471292.1
ENST00000391763.3
ENST00000391764.3
ENST00000303553.5
NDUFA3
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa
chr17_-_1928621 0.12 ENST00000331238.6
RTN4RL1
reticulon 4 receptor-like 1
chr18_-_43678241 0.12 ENST00000593152.2
ENST00000589252.1
ENST00000590665.1
ENST00000398752.6
ATP5A1
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
chr3_+_179322481 0.12 ENST00000259037.3
NDUFB5
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
chr1_-_33502528 0.12 ENST00000354858.6
AK2
adenylate kinase 2
chr12_+_65672702 0.11 ENST00000538045.1
ENST00000535239.1
MSRB3
methionine sulfoxide reductase B3
chr6_-_89673280 0.11 ENST00000369475.3
ENST00000369485.4
ENST00000538899.1
ENST00000265607.6
RNGTT
RNA guanylyltransferase and 5'-phosphatase
chr9_-_35103105 0.11 ENST00000452248.2
ENST00000356493.5
STOML2
stomatin (EPB72)-like 2
chr8_-_100905925 0.11 ENST00000518171.1
COX6C
cytochrome c oxidase subunit VIc
chr10_+_75757863 0.11 ENST00000372755.3
ENST00000211998.4
ENST00000417648.2
VCL
vinculin
chr7_-_150777920 0.10 ENST00000353841.2
ENST00000297532.6
FASTK
Fas-activated serine/threonine kinase
chr12_-_53320245 0.10 ENST00000552150.1
KRT8
keratin 8
chr2_+_198365095 0.10 ENST00000409468.1
HSPE1
heat shock 10kDa protein 1
chr15_+_45422131 0.10 ENST00000321429.4
DUOX1
dual oxidase 1
chr20_+_3776371 0.10 ENST00000245960.5
CDC25B
cell division cycle 25B
chr16_+_2076869 0.10 ENST00000424542.2
ENST00000432365.2
SLC9A3R2
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
chr2_+_207024306 0.10 ENST00000236957.5
ENST00000392221.1
ENST00000392222.2
ENST00000445505.1
EEF1B2
eukaryotic translation elongation factor 1 beta 2
chr11_-_111741994 0.10 ENST00000398006.2
ALG9
ALG9, alpha-1,2-mannosyltransferase
chr11_-_7985193 0.10 ENST00000328600.2
NLRP10
NLR family, pyrin domain containing 10
chr6_-_52109335 0.09 ENST00000336123.4
IL17F
interleukin 17F
chr12_+_65672423 0.09 ENST00000355192.3
ENST00000308259.5
ENST00000540804.1
ENST00000535664.1
ENST00000541189.1
MSRB3
methionine sulfoxide reductase B3
chr2_-_207024233 0.09 ENST00000423725.1
ENST00000233190.6
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr15_+_45422178 0.09 ENST00000389037.3
ENST00000558322.1
DUOX1
dual oxidase 1
chr7_-_150777949 0.09 ENST00000482571.1
FASTK
Fas-activated serine/threonine kinase
chr19_+_8478154 0.09 ENST00000381035.4
ENST00000595142.1
ENST00000601724.1
ENST00000393944.1
ENST00000215555.2
ENST00000601283.1
ENST00000595213.1
MARCH2
membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
chr1_+_206858232 0.09 ENST00000294981.4
MAPKAPK2
mitogen-activated protein kinase-activated protein kinase 2
chr3_+_45067659 0.08 ENST00000296130.4
CLEC3B
C-type lectin domain family 3, member B
chr9_-_35685452 0.08 ENST00000607559.1
TPM2
tropomyosin 2 (beta)
chr12_+_120875887 0.08 ENST00000229379.2
COX6A1
cytochrome c oxidase subunit VIa polypeptide 1
chr9_+_134103496 0.07 ENST00000498010.1
ENST00000476004.1
ENST00000528406.1
NUP214
nucleoporin 214kDa
chr6_-_71012773 0.07 ENST00000370496.3
ENST00000357250.6
COL9A1
collagen, type IX, alpha 1
chr11_-_6462210 0.07 ENST00000265983.3
HPX
hemopexin
chr7_+_100612904 0.07 ENST00000379442.3
ENST00000536621.1
MUC12
mucin 12, cell surface associated
chr8_-_100905850 0.06 ENST00000520271.1
ENST00000522940.1
ENST00000523016.1
ENST00000517682.2
ENST00000297564.2
COX6C
cytochrome c oxidase subunit VIc
chr13_-_76111945 0.06 ENST00000355801.4
ENST00000406936.3
COMMD6
COMM domain containing 6
chr9_-_86322831 0.06 ENST00000257468.7
UBQLN1
ubiquilin 1
chr1_-_33502441 0.06 ENST00000548033.1
ENST00000487289.1
ENST00000373449.2
ENST00000480134.1
ENST00000467905.1
AK2
adenylate kinase 2
chr12_+_10366016 0.06 ENST00000546017.1
ENST00000535576.1
ENST00000539170.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr2_+_198365122 0.06 ENST00000604458.1
HSPE1-MOB4
HSPE1-MOB4 readthrough
chr1_+_43148059 0.06 ENST00000321358.7
ENST00000332220.6
YBX1
Y box binding protein 1
chr14_-_102552659 0.05 ENST00000441629.2
HSP90AA1
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr20_+_3776936 0.05 ENST00000439880.2
CDC25B
cell division cycle 25B
chr17_+_48423453 0.05 ENST00000017003.2
ENST00000509778.1
ENST00000507602.1
XYLT2
xylosyltransferase II
chr17_-_4458616 0.05 ENST00000381556.2
MYBBP1A
MYB binding protein (P160) 1a
chr15_-_75017711 0.05 ENST00000567032.1
ENST00000564596.1
ENST00000566503.1
ENST00000395049.4
ENST00000395048.2
ENST00000379727.3
CYP1A1
cytochrome P450, family 1, subfamily A, polypeptide 1
chr8_-_100905363 0.05 ENST00000524245.1
COX6C
cytochrome c oxidase subunit VIc
chr7_+_123241908 0.05 ENST00000434204.1
ENST00000437535.1
ENST00000451215.1
ASB15
ankyrin repeat and SOCS box containing 15
chr11_+_118272328 0.04 ENST00000524422.1
ATP5L
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G
chr20_-_3748416 0.04 ENST00000399672.1
C20orf27
chromosome 20 open reading frame 27
chr1_-_26197744 0.04 ENST00000374296.3
PAQR7
progestin and adipoQ receptor family member VII
chr6_-_43021437 0.04 ENST00000265348.3
CUL7
cullin 7
chr5_-_140027357 0.04 ENST00000252102.4
NDUFA2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
chr1_-_153522562 0.04 ENST00000368714.1
S100A4
S100 calcium binding protein A4
chr7_+_73868439 0.04 ENST00000424337.2
GTF2IRD1
GTF2I repeat domain containing 1
chr19_-_39926268 0.03 ENST00000599705.1
RPS16
ribosomal protein S16
chr12_-_6484376 0.03 ENST00000360168.3
ENST00000358945.3
SCNN1A
sodium channel, non-voltage-gated 1 alpha subunit
chr19_-_55669093 0.03 ENST00000344887.5
TNNI3
troponin I type 3 (cardiac)
chr14_-_107114267 0.03 ENST00000454421.2
IGHV3-64
immunoglobulin heavy variable 3-64
chr6_+_52051171 0.03 ENST00000340057.1
IL17A
interleukin 17A
chr9_-_116065551 0.02 ENST00000297894.5
RNF183
ring finger protein 183
chr3_+_10068095 0.02 ENST00000287647.3
ENST00000383807.1
ENST00000383806.1
ENST00000419585.1
FANCD2
Fanconi anemia, complementation group D2
chr6_+_30594619 0.02 ENST00000318999.7
ENST00000376485.4
ENST00000376478.2
ENST00000319027.5
ENST00000376483.4
ENST00000329992.8
ENST00000330083.5
ATAT1
alpha tubulin acetyltransferase 1
chr11_-_790060 0.02 ENST00000330106.4
CEND1
cell cycle exit and neuronal differentiation 1
chr16_+_28875126 0.02 ENST00000359285.5
ENST00000538342.1
SH2B1
SH2B adaptor protein 1
chr3_-_49158218 0.02 ENST00000417901.1
ENST00000306026.5
ENST00000434032.2
USP19
ubiquitin specific peptidase 19
chr14_-_101295407 0.02 ENST00000596284.1
AL117190.2
AL117190.2
chr20_-_13971255 0.02 ENST00000284951.5
ENST00000378072.5
SEL1L2
sel-1 suppressor of lin-12-like 2 (C. elegans)
chr1_-_157108130 0.02 ENST00000368192.4
ETV3
ets variant 3
chr2_-_207024134 0.01 ENST00000457011.1
ENST00000440274.1
ENST00000432169.1
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr1_-_241799232 0.01 ENST00000366553.1
CHML
choroideremia-like (Rab escort protein 2)
chr11_-_64511575 0.01 ENST00000431822.1
ENST00000377486.3
ENST00000394432.3
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr5_-_140027175 0.01 ENST00000512088.1
NDUFA2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
chr13_+_22245522 0.01 ENST00000382353.5
FGF9
fibroblast growth factor 9
chrX_-_30327495 0.01 ENST00000453287.1
NR0B1
nuclear receptor subfamily 0, group B, member 1
chr11_+_86667117 0.01 ENST00000531827.1
RP11-736K20.6
RP11-736K20.6
chr16_+_56899114 0.00 ENST00000566786.1
ENST00000438926.2
ENST00000563236.1
ENST00000262502.5
SLC12A3
solute carrier family 12 (sodium/chloride transporter), member 3
chr19_+_38924316 0.00 ENST00000355481.4
ENST00000360985.3
ENST00000359596.3
RYR1
ryanodine receptor 1 (skeletal)

Network of associatons between targets according to the STRING database.

First level regulatory network of RORA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.3 0.9 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.2 4.9 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 0.5 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.1 0.3 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.3 GO:0006097 glyoxylate cycle(GO:0006097)
0.1 0.7 GO:1904044 response to aldosterone(GO:1904044)
0.1 0.6 GO:0097501 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.1 0.3 GO:0090301 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.1 0.2 GO:0007518 myoblast fate determination(GO:0007518)
0.1 0.3 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.1 0.4 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 0.2 GO:1903028 positive regulation of opsonization(GO:1903028)
0.1 0.2 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.1 1.0 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 1.0 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.2 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 0.2 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.6 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.3 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 1.3 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.2 GO:0071105 response to interleukin-11(GO:0071105)
0.0 0.1 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.0 0.1 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.6 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.2 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.2 GO:0042335 cuticle development(GO:0042335)
0.0 0.2 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 3.1 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.3 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.6 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0 0.1 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894)
0.0 0.1 GO:0042109 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0 0.4 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.3 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.7 GO:0030728 ovulation(GO:0030728)
0.0 0.4 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.1 GO:2000318 positive regulation of T-helper 17 type immune response(GO:2000318)
0.0 0.2 GO:0030091 protein repair(GO:0030091)
0.0 0.3 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.1 GO:0034140 negative regulation of toll-like receptor 3 signaling pathway(GO:0034140)
0.0 0.2 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:0098501 polynucleotide dephosphorylation(GO:0098501)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.2 GO:0007144 female meiosis I(GO:0007144)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 0.6 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 0.1 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 0.7 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.2 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 0.4 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.1 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.3 GO:0035855 megakaryocyte development(GO:0035855)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 0.3 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 0.3 GO:0005607 laminin-2 complex(GO:0005607)
0.1 0.6 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.2 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.5 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.1 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.3 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.1 GO:0070470 plasma membrane respiratory chain complex I(GO:0045272) plasma membrane respiratory chain(GO:0070470)
0.0 1.0 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.2 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.1 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.1 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.5 GO:0008305 integrin complex(GO:0008305)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.9 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.3 2.0 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.2 0.5 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.1 0.3 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450) (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.1 0.4 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.1 3.1 GO:0004950 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.1 0.2 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.1 1.0 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.2 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.1 0.3 GO:0017040 ceramidase activity(GO:0017040)
0.0 1.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.3 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.2 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.6 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.7 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.4 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.1 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.6 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 1.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.1 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.2 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.7 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.2 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.1 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.0 0.1 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.7 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.1 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.1 GO:0035374 chondroitin sulfate binding(GO:0035374)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 4.9 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.9 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.6 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.6 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.9 PID ATF2 PATHWAY ATF-2 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.1 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 2.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.6 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 0.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.0 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins