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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for RREB1

Z-value: 0.80

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Transcription factors associated with RREB1

Gene Symbol Gene ID Gene Info
RREB1
ENSG00000124782.15 ras responsive element binding protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RREB1hg19_v2_chr6_+_7107830_7107993,
hg19_v2_chr6_+_7108210_7108264		-0.222.9e-01Click!

Activity profile of RREB1 motif

Sorted Z-values of RREB1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_61548374 4.04 ENST00000485903.2
ENST00000371185.2
ENST00000371184.2
NFIA
nuclear factor I/A
chr13_-_72441315 4.03 ENST00000305425.4
ENST00000313174.7
ENST00000354591.4
DACH1
dachshund homolog 1 (Drosophila)
chr1_+_61548225 3.30 ENST00000371187.3
NFIA
nuclear factor I/A
chr8_-_22550815 3.05 ENST00000317216.2
EGR3
early growth response 3
chr12_+_96588279 2.81 ENST00000552142.1
ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr2_+_48757278 1.84 ENST00000404752.1
ENST00000406226.1
STON1
stonin 1
chr3_-_18466026 1.81 ENST00000417717.2
SATB1
SATB homeobox 1
chr13_-_72440901 1.80 ENST00000359684.2
DACH1
dachshund homolog 1 (Drosophila)
chr1_+_164528866 1.77 ENST00000420696.2
PBX1
pre-B-cell leukemia homeobox 1
chr9_-_14314066 1.74 ENST00000397575.3
NFIB
nuclear factor I/B
chr14_-_105635090 1.60 ENST00000331782.3
ENST00000347004.2
JAG2
jagged 2
chr2_-_136873735 1.46 ENST00000409817.1
CXCR4
chemokine (C-X-C motif) receptor 4
chr11_+_125034586 1.39 ENST00000298282.9
PKNOX2
PBX/knotted 1 homeobox 2
chr9_-_14313893 1.37 ENST00000380921.3
ENST00000380959.3
NFIB
nuclear factor I/B
chr4_+_123747979 1.34 ENST00000608478.1
FGF2
fibroblast growth factor 2 (basic)
chr4_+_123747834 1.32 ENST00000264498.3
FGF2
fibroblast growth factor 2 (basic)
chr20_+_34700333 1.31 ENST00000441639.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr12_-_95044309 1.30 ENST00000261226.4
TMCC3
transmembrane and coiled-coil domain family 3
chr9_-_13279406 1.22 ENST00000546205.1
MPDZ
multiple PDZ domain protein
chr4_+_74735102 1.19 ENST00000395761.3
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr16_-_4588469 1.19 ENST00000588381.1
ENST00000563332.2
CDIP1
cell death-inducing p53 target 1
chr20_+_62697564 1.15 ENST00000458442.1
TCEA2
transcription elongation factor A (SII), 2
chr7_+_114562172 1.15 ENST00000393486.1
ENST00000257724.3
MDFIC
MyoD family inhibitor domain containing
chr20_-_36793663 1.14 ENST00000536701.1
ENST00000536724.1
TGM2
transglutaminase 2
chr2_+_28618532 1.14 ENST00000545753.1
FOSL2
FOS-like antigen 2
chr17_+_7788104 1.12 ENST00000380358.4
CHD3
chromodomain helicase DNA binding protein 3
chr9_-_13279563 1.07 ENST00000541718.1
MPDZ
multiple PDZ domain protein
chr19_-_19051927 1.03 ENST00000600077.1
HOMER3
homer homolog 3 (Drosophila)
chr19_-_19051993 0.94 ENST00000594794.1
ENST00000355887.6
ENST00000392351.3
ENST00000596482.1
HOMER3
homer homolog 3 (Drosophila)
chr11_-_71791435 0.94 ENST00000351960.6
ENST00000541719.1
ENST00000535111.1
NUMA1
nuclear mitotic apparatus protein 1
chr12_-_120687948 0.93 ENST00000458477.2
PXN
paxillin
chr11_-_71791518 0.92 ENST00000537217.1
ENST00000366394.3
ENST00000358965.6
ENST00000546131.1
ENST00000543937.1
ENST00000368959.5
ENST00000541641.1
NUMA1
nuclear mitotic apparatus protein 1
chr11_-_89224488 0.92 ENST00000534731.1
ENST00000527626.1
NOX4
NADPH oxidase 4
chr19_-_18995029 0.92 ENST00000596048.1
CERS1
ceramide synthase 1
chr18_+_77160282 0.90 ENST00000318065.5
ENST00000545796.1
ENST00000592223.1
ENST00000329101.4
ENST00000586434.1
NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr11_-_71791726 0.89 ENST00000393695.3
NUMA1
nuclear mitotic apparatus protein 1
chr9_-_13279589 0.89 ENST00000319217.7
MPDZ
multiple PDZ domain protein
chr16_-_4588822 0.89 ENST00000564828.1
CDIP1
cell death-inducing p53 target 1
chr17_-_39728303 0.85 ENST00000588431.1
ENST00000246662.4
KRT9
keratin 9
chr16_-_4588762 0.84 ENST00000562334.1
ENST00000562579.1
ENST00000567695.1
ENST00000563507.1
CDIP1
cell death-inducing p53 target 1
chr17_+_79373540 0.84 ENST00000307745.7
RP11-1055B8.7
BAH and coiled-coil domain-containing protein 1
chr8_+_144816303 0.79 ENST00000533004.1
FAM83H-AS1
FAM83H antisense RNA 1 (head to head)
chr17_+_58499844 0.78 ENST00000269127.4
C17orf64
chromosome 17 open reading frame 64
chr9_+_35906176 0.77 ENST00000354323.2
HRCT1
histidine rich carboxyl terminus 1
chr10_-_126849588 0.77 ENST00000411419.2
CTBP2
C-terminal binding protein 2
chr8_+_28748099 0.77 ENST00000519047.1
HMBOX1
homeobox containing 1
chr13_-_37494365 0.75 ENST00000350148.5
SMAD9
SMAD family member 9
chr13_-_37494391 0.73 ENST00000379826.4
SMAD9
SMAD family member 9
chr7_-_132262060 0.73 ENST00000359827.3
PLXNA4
plexin A4
chr16_-_49890016 0.73 ENST00000563137.2
ZNF423
zinc finger protein 423
chr20_-_45984401 0.71 ENST00000311275.7
ZMYND8
zinc finger, MYND-type containing 8
chr2_+_234104079 0.68 ENST00000417661.1
INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr5_+_175299743 0.66 ENST00000502265.1
CPLX2
complexin 2
chr3_-_39196049 0.64 ENST00000514182.1
CSRNP1
cysteine-serine-rich nuclear protein 1
chrX_+_118108571 0.63 ENST00000304778.7
LONRF3
LON peptidase N-terminal domain and ring finger 3
chr9_+_96026230 0.62 ENST00000448251.1
WNK2
WNK lysine deficient protein kinase 2
chr4_+_190992087 0.61 ENST00000553598.1
DUX4L7
double homeobox 4 like 7
chr13_-_74708372 0.61 ENST00000377666.4
KLF12
Kruppel-like factor 12
chr11_+_7506713 0.60 ENST00000329293.3
ENST00000534244.1
OLFML1
olfactomedin-like 1
chr8_+_28748765 0.59 ENST00000355231.5
HMBOX1
homeobox containing 1
chr17_-_7082861 0.59 ENST00000269299.3
ASGR1
asialoglycoprotein receptor 1
chr14_+_57735614 0.58 ENST00000261558.3
AP5M1
adaptor-related protein complex 5, mu 1 subunit
chr18_+_9334755 0.57 ENST00000262120.5
TWSG1
twisted gastrulation BMP signaling modulator 1
chr19_-_3025614 0.57 ENST00000447365.2
TLE2
transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr6_+_37321748 0.56 ENST00000373479.4
ENST00000394443.4
RNF8
ring finger protein 8, E3 ubiquitin protein ligase
chr12_+_96588143 0.55 ENST00000228741.3
ENST00000547249.1
ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr4_+_190995380 0.55 ENST00000555191.1
DUX4L6
double homeobox 4 like 6
chr2_-_128432639 0.55 ENST00000545738.2
ENST00000355119.4
ENST00000409808.2
LIMS2
LIM and senescent cell antigen-like domains 2
chr8_-_66754172 0.54 ENST00000401827.3
PDE7A
phosphodiesterase 7A
chr1_-_149889382 0.54 ENST00000369145.1
ENST00000369146.3
SV2A
synaptic vesicle glycoprotein 2A
chrX_+_17755563 0.54 ENST00000380045.3
ENST00000380041.3
ENST00000380043.3
ENST00000398080.1
SCML1
sex comb on midleg-like 1 (Drosophila)
chr4_+_190998973 0.52 ENST00000605696.1
ENST00000557283.2
DUX4L5
double homeobox 4 like 5
chr3_-_47517302 0.52 ENST00000441517.2
ENST00000545718.1
SCAP
SREBF chaperone
chr4_+_190995680 0.52 ENST00000605381.1
ENST00000553722.2
DUX4L6
double homeobox 4 like 6
chr6_-_13486369 0.52 ENST00000558378.1
AL583828.1
AL583828.1
chr17_-_43502987 0.51 ENST00000376922.2
ARHGAP27
Rho GTPase activating protein 27
chr1_-_21377383 0.51 ENST00000374935.3
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr4_+_190998673 0.51 ENST00000554668.1
DUX4L5
double homeobox 4 like 5
chr4_+_190992387 0.51 ENST00000554906.2
ENST00000553820.2
DUX4L7
double homeobox 4 like 7
chr4_+_191008860 0.51 ENST00000605191.1
ENST00000557656.2
DUX4L3
double homeobox 4 like 3
chr4_+_191005567 0.51 ENST00000605758.1
ENST00000554285.2
DUX4
double homeobox 4
chr4_+_191012160 0.51 ENST00000553702.1
ENST00000554376.1
DUX4L2
double homeobox 4 like 2
chr4_+_191005267 0.51 ENST00000556625.1
DUX4
double homeobox 4
chr4_+_191011860 0.51 ENST00000440426.1
DUX4L2
double homeobox 4 like 2
chr4_+_191008560 0.51 ENST00000554690.1
DUX4L3
double homeobox 4 like 3
chr19_-_42759300 0.51 ENST00000222329.4
ERF
Ets2 repressor factor
chr1_-_17307173 0.51 ENST00000438542.1
ENST00000375535.3
MFAP2
microfibrillar-associated protein 2
chr19_-_3029011 0.50 ENST00000590536.1
ENST00000587137.1
ENST00000455444.2
ENST00000262953.6
TLE2
transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr1_-_94586651 0.49 ENST00000535735.1
ENST00000370225.3
ABCA4
ATP-binding cassette, sub-family A (ABC1), member 4
chr19_-_48867291 0.48 ENST00000435956.3
TMEM143
transmembrane protein 143
chr7_+_75932863 0.46 ENST00000429938.1
HSPB1
heat shock 27kDa protein 1
chr19_+_34287751 0.46 ENST00000590771.1
ENST00000589786.1
ENST00000284006.6
ENST00000588881.1
KCTD15
potassium channel tetramerization domain containing 15
chr17_+_6926339 0.45 ENST00000293805.5
BCL6B
B-cell CLL/lymphoma 6, member B
chr16_-_31439735 0.43 ENST00000287490.4
COX6A2
cytochrome c oxidase subunit VIa polypeptide 2
chr20_+_33462888 0.42 ENST00000336325.4
ACSS2
acyl-CoA synthetase short-chain family member 2
chr17_-_39677971 0.42 ENST00000393976.2
KRT15
keratin 15
chr16_-_28303360 0.42 ENST00000501520.1
RP11-57A19.2
RP11-57A19.2
chr19_+_42381337 0.41 ENST00000597454.1
ENST00000444740.2
CD79A
CD79a molecule, immunoglobulin-associated alpha
chr19_+_18544045 0.40 ENST00000599699.2
SSBP4
single stranded DNA binding protein 4
chr16_-_75301886 0.40 ENST00000393422.2
BCAR1
breast cancer anti-estrogen resistance 1
chr7_-_752074 0.39 ENST00000360274.4
PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
chrX_+_151081351 0.39 ENST00000276344.2
MAGEA4
melanoma antigen family A, 4
chr11_-_118436606 0.39 ENST00000530872.1
IFT46
intraflagellar transport 46 homolog (Chlamydomonas)
chr19_+_7828035 0.39 ENST00000327325.5
ENST00000394122.2
ENST00000248228.4
ENST00000334806.5
ENST00000359059.5
ENST00000357361.2
ENST00000596363.1
ENST00000595751.1
ENST00000596707.1
ENST00000597522.1
ENST00000595496.1
CLEC4M
C-type lectin domain family 4, member M
chr19_-_18653781 0.38 ENST00000596558.2
ENST00000453489.2
FKBP8
FK506 binding protein 8, 38kDa
chr7_+_95401851 0.37 ENST00000447467.2
DYNC1I1
dynein, cytoplasmic 1, intermediate chain 1
chr12_-_8088871 0.37 ENST00000075120.7
SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr12_-_6233828 0.36 ENST00000572068.1
ENST00000261405.5
VWF
von Willebrand factor
chr17_+_35849937 0.36 ENST00000394389.4
DUSP14
dual specificity phosphatase 14
chr12_-_7261772 0.36 ENST00000545280.1
ENST00000543933.1
ENST00000545337.1
ENST00000544702.1
ENST00000266542.4
C1RL
complement component 1, r subcomponent-like
chr16_+_58533951 0.35 ENST00000566192.1
ENST00000565088.1
ENST00000568640.1
ENST00000563978.1
ENST00000569923.1
ENST00000356752.4
ENST00000563799.1
ENST00000562999.1
ENST00000570248.1
ENST00000562731.1
ENST00000568424.1
NDRG4
NDRG family member 4
chr5_+_150591678 0.35 ENST00000523466.1
GM2A
GM2 ganglioside activator
chrX_+_128674213 0.35 ENST00000371113.4
ENST00000357121.5
OCRL
oculocerebrorenal syndrome of Lowe
chr21_-_47648665 0.35 ENST00000450351.1
ENST00000522411.1
ENST00000356396.4
ENST00000397728.3
ENST00000457828.2
LSS
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
chr13_-_76056250 0.35 ENST00000377636.3
ENST00000431480.2
ENST00000377625.2
ENST00000425511.1
TBC1D4
TBC1 domain family, member 4
chr3_+_57094469 0.35 ENST00000334325.1
SPATA12
spermatogenesis associated 12
chr16_+_68771128 0.34 ENST00000261769.5
ENST00000422392.2
CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr19_+_55476620 0.33 ENST00000543010.1
ENST00000391721.4
ENST00000339757.7
NLRP2
NLR family, pyrin domain containing 2
chr17_+_38474489 0.33 ENST00000394089.2
ENST00000425707.3
RARA
retinoic acid receptor, alpha
chr17_+_1733276 0.33 ENST00000254719.5
RPA1
replication protein A1, 70kDa
chr5_+_138629628 0.33 ENST00000508689.1
ENST00000514528.1
MATR3
matrin 3
chr16_-_28503327 0.33 ENST00000535392.1
ENST00000395653.4
CLN3
ceroid-lipofuscinosis, neuronal 3
chr11_+_46402744 0.33 ENST00000533952.1
MDK
midkine (neurite growth-promoting factor 2)
chr3_+_186435137 0.32 ENST00000447445.1
KNG1
kininogen 1
chr7_+_91570165 0.32 ENST00000356239.3
ENST00000359028.2
ENST00000358100.2
AKAP9
A kinase (PRKA) anchor protein 9
chr19_+_51358166 0.32 ENST00000601503.1
ENST00000326003.2
ENST00000597286.1
ENST00000597483.1
KLK3
kallikrein-related peptidase 3
chr16_-_28503357 0.32 ENST00000333496.9
ENST00000561505.1
ENST00000567963.1
ENST00000354630.5
ENST00000355477.5
ENST00000357076.5
ENST00000565688.1
ENST00000359984.7
CLN3
ceroid-lipofuscinosis, neuronal 3
chr10_-_126849068 0.30 ENST00000494626.2
ENST00000337195.5
CTBP2
C-terminal binding protein 2
chr5_-_35195338 0.30 ENST00000509839.1
PRLR
prolactin receptor
chrX_+_51636629 0.29 ENST00000375722.1
ENST00000326587.7
ENST00000375695.2
MAGED1
melanoma antigen family D, 1
chr19_+_55477711 0.29 ENST00000448584.2
ENST00000537859.1
ENST00000585500.1
ENST00000427260.2
ENST00000538819.1
ENST00000263437.6
NLRP2
NLR family, pyrin domain containing 2
chr16_-_28503080 0.29 ENST00000565316.1
ENST00000565778.1
ENST00000357857.9
ENST00000568558.1
ENST00000357806.7
CLN3
ceroid-lipofuscinosis, neuronal 3
chr7_-_71801980 0.28 ENST00000329008.5
CALN1
calneuron 1
chr10_-_121356518 0.28 ENST00000369092.4
TIAL1
TIA1 cytotoxic granule-associated RNA binding protein-like 1
chrX_-_148669116 0.28 ENST00000243314.5
MAGEA9B
melanoma antigen family A, 9B
chrX_+_102631844 0.27 ENST00000372634.1
ENST00000299872.7
NGFRAP1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr4_-_148605265 0.27 ENST00000541232.1
ENST00000322396.6
PRMT10
protein arginine methyltransferase 10 (putative)
chr18_-_21242774 0.27 ENST00000322980.9
ANKRD29
ankyrin repeat domain 29
chr13_+_60971427 0.27 ENST00000535286.1
ENST00000377881.2
TDRD3
tudor domain containing 3
chr11_+_818902 0.26 ENST00000336615.4
PNPLA2
patatin-like phospholipase domain containing 2
chrX_-_148571884 0.26 ENST00000537071.1
IDS
iduronate 2-sulfatase
chr9_-_116163400 0.26 ENST00000277315.5
ENST00000448137.1
ENST00000409155.3
ALAD
aminolevulinate dehydratase
chr1_+_24104869 0.25 ENST00000246151.4
PITHD1
PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1
chr11_+_66406088 0.25 ENST00000310092.7
ENST00000396053.4
ENST00000408993.2
RBM4
RNA binding motif protein 4
chr1_+_18958008 0.25 ENST00000420770.2
ENST00000400661.3
PAX7
paired box 7
chr19_-_47975417 0.25 ENST00000236877.6
SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr12_-_123756781 0.25 ENST00000544658.1
CDK2AP1
cyclin-dependent kinase 2 associated protein 1
chr19_+_55999916 0.25 ENST00000587166.1
ENST00000389623.6
SSC5D
scavenger receptor cysteine rich domain containing (5 domains)
chr19_+_51358191 0.25 ENST00000593997.1
ENST00000595952.1
ENST00000360617.3
ENST00000598145.1
KLK3
kallikrein-related peptidase 3
chr2_-_179343226 0.25 ENST00000434643.2
FKBP7
FK506 binding protein 7
chr1_-_204380919 0.24 ENST00000367188.4
PPP1R15B
protein phosphatase 1, regulatory subunit 15B
chr6_+_37321823 0.23 ENST00000487950.1
ENST00000469731.1
RNF8
ring finger protein 8, E3 ubiquitin protein ligase
chr11_-_74109422 0.23 ENST00000298198.4
PGM2L1
phosphoglucomutase 2-like 1
chr17_-_79817091 0.23 ENST00000570907.1
P4HB
prolyl 4-hydroxylase, beta polypeptide
chr12_-_123756687 0.23 ENST00000261692.2
CDK2AP1
cyclin-dependent kinase 2 associated protein 1
chr12_+_57916584 0.22 ENST00000546632.1
ENST00000549623.1
ENST00000431731.2
MBD6
methyl-CpG binding domain protein 6
chrX_+_148863584 0.22 ENST00000439010.2
ENST00000298974.5
ENST00000522429.1
ENST00000519822.1
MAGEA9
melanoma antigen family A, 9
chrX_+_151903207 0.22 ENST00000370287.3
CSAG1
chondrosarcoma associated gene 1
chr15_-_23692381 0.21 ENST00000567107.1
ENST00000345070.5
ENST00000312015.5
GOLGA6L2
golgin A6 family-like 2
chr7_+_94537542 0.21 ENST00000433881.1
PPP1R9A
protein phosphatase 1, regulatory subunit 9A
chr7_+_39125365 0.21 ENST00000559001.1
ENST00000464276.2
POU6F2
POU class 6 homeobox 2
chr5_+_139505520 0.21 ENST00000333305.3
IGIP
IgA-inducing protein
chr2_-_54087066 0.21 ENST00000394705.2
ENST00000352846.3
ENST00000406625.2
GPR75
GPR75-ASB3
ASB3
G protein-coupled receptor 75
GPR75-ASB3 readthrough
Ankyrin repeat and SOCS box protein 3
chr19_-_18654293 0.21 ENST00000597547.1
ENST00000222308.4
ENST00000544835.3
ENST00000610101.1
ENST00000597960.3
ENST00000608443.1
FKBP8
FK506 binding protein 8, 38kDa
chr14_+_100485712 0.21 ENST00000544450.2
EVL
Enah/Vasp-like
chr17_-_73761222 0.21 ENST00000437911.1
ENST00000225614.2
GALK1
galactokinase 1
chr19_-_39226045 0.20 ENST00000597987.1
ENST00000595177.1
CAPN12
calpain 12
chrX_+_153813407 0.20 ENST00000443287.2
ENST00000333128.3
CTAG1A
cancer/testis antigen 1A
chr10_-_95360983 0.20 ENST00000371464.3
RBP4
retinol binding protein 4, plasma
chr5_+_138629417 0.20 ENST00000510056.1
ENST00000511249.1
ENST00000503811.1
ENST00000511378.1
MATR3
matrin 3
chr16_+_447209 0.20 ENST00000382940.4
ENST00000219479.2
NME4
NME/NM23 nucleoside diphosphate kinase 4
chr7_-_38398721 0.19 ENST00000390346.2
TRGV3
T cell receptor gamma variable 3
chr11_+_61197572 0.19 ENST00000542074.1
ENST00000534878.1
ENST00000537782.1
ENST00000543265.1
SDHAF2
succinate dehydrogenase complex assembly factor 2
chr17_-_7082668 0.18 ENST00000573083.1
ENST00000574388.1
ASGR1
asialoglycoprotein receptor 1
chr12_+_57916466 0.18 ENST00000355673.3
MBD6
methyl-CpG binding domain protein 6
chr1_-_226111929 0.18 ENST00000343818.6
ENST00000432920.2
PYCR2
RP4-559A3.7
pyrroline-5-carboxylate reductase family, member 2
Uncharacterized protein
chrX_+_151903253 0.18 ENST00000452779.2
ENST00000370291.2
CSAG1
chondrosarcoma associated gene 1
chr17_+_58227287 0.17 ENST00000300900.4
ENST00000591725.1
CA4
carbonic anhydrase IV
chr11_-_61197480 0.17 ENST00000439958.3
ENST00000394888.4
CPSF7
cleavage and polyadenylation specific factor 7, 59kDa
chr12_+_49212514 0.17 ENST00000301050.2
ENST00000548279.1
ENST00000547230.1
CACNB3
calcium channel, voltage-dependent, beta 3 subunit
chr6_+_168227611 0.17 ENST00000344191.4
ENST00000351017.4
ENST00000392108.3
ENST00000366806.2
ENST00000392112.1
ENST00000400824.4
ENST00000447894.2
ENST00000400822.3
MLLT4
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
chr2_+_219745020 0.16 ENST00000258411.3
WNT10A
wingless-type MMTV integration site family, member 10A
chr12_+_58003935 0.16 ENST00000333972.7
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chrX_-_77041685 0.16 ENST00000373344.5
ENST00000395603.3
ATRX
alpha thalassemia/mental retardation syndrome X-linked
chr19_-_51192661 0.16 ENST00000391813.1
SHANK1
SH3 and multiple ankyrin repeat domains 1
chr12_+_16064258 0.16 ENST00000524480.1
ENST00000531803.1
ENST00000532964.1
DERA
deoxyribose-phosphate aldolase (putative)
chr19_-_33555780 0.15 ENST00000254260.3
ENST00000400226.4
RHPN2
rhophilin, Rho GTPase binding protein 2
chr3_+_41240986 0.15 ENST00000396185.3
CTNNB1
catenin (cadherin-associated protein), beta 1, 88kDa
chr2_+_85843252 0.15 ENST00000409025.1
ENST00000409470.1
ENST00000323701.6
ENST00000409766.3
USP39
ubiquitin specific peptidase 39
chr14_-_71067360 0.15 ENST00000554963.1
ENST00000430055.2
ENST00000440435.2
ENST00000256379.5
MED6
mediator complex subunit 6
chr7_+_95401877 0.14 ENST00000524053.1
ENST00000324972.6
ENST00000537881.1
ENST00000437599.1
ENST00000359388.4
ENST00000413338.1
DYNC1I1
dynein, cytoplasmic 1, intermediate chain 1
chr11_+_61197508 0.14 ENST00000541135.1
ENST00000301761.2
RP11-286N22.8
SDHAF2
Uncharacterized protein
succinate dehydrogenase complex assembly factor 2
chrX_+_134166333 0.14 ENST00000257013.7
FAM127A
family with sequence similarity 127, member A
chr11_-_61197187 0.14 ENST00000449811.1
ENST00000413232.1
ENST00000340437.4
ENST00000539952.1
ENST00000544585.1
ENST00000450000.1
CPSF7
cleavage and polyadenylation specific factor 7, 59kDa
chr3_+_169684553 0.14 ENST00000337002.4
ENST00000480708.1
SEC62
SEC62 homolog (S. cerevisiae)
chr7_+_1022811 0.14 ENST00000308919.7
CYP2W1
cytochrome P450, family 2, subfamily W, polypeptide 1
chr11_-_2323290 0.13 ENST00000381153.3
C11orf21
chromosome 11 open reading frame 21
chr11_-_2323089 0.13 ENST00000456145.2
C11orf21
chromosome 11 open reading frame 21
chr5_+_76145826 0.13 ENST00000513010.1
S100Z
S100 calcium binding protein Z
chr1_+_212782012 0.13 ENST00000341491.4
ENST00000366985.1
ATF3
activating transcription factor 3

Network of associatons between targets according to the STRING database.

First level regulatory network of RREB1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:1902846 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.7 5.8 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.4 3.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.4 4.6 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.4 1.1 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.4 2.7 GO:1904849 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.3 0.9 GO:0072720 cellular response to mycotoxin(GO:0036146) response to dithiothreitol(GO:0072720)
0.3 7.3 GO:0072189 ureter development(GO:0072189)
0.2 0.7 GO:0021793 chemorepulsion of branchiomotor axon(GO:0021793)
0.2 0.9 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.2 0.7 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.2 1.5 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.1 1.0 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.1 0.5 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.1 1.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 0.7 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1 0.5 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.1 0.3 GO:0034552 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.1 0.2 GO:0043385 mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
0.1 0.4 GO:0019541 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.1 0.4 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.1 0.5 GO:0030421 defecation(GO:0030421)
0.1 0.3 GO:0071284 response to platinum ion(GO:0070541) cellular response to lead ion(GO:0071284)
0.1 0.3 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 1.2 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.2 GO:0031448 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.1 0.6 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 0.4 GO:0046968 peptide antigen transport(GO:0046968)
0.1 2.0 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 1.4 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.1 0.5 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 0.2 GO:1904048 regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.1 0.2 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.1 0.1 GO:1901963 regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901963)
0.1 0.2 GO:0006059 hexitol metabolic process(GO:0006059)
0.1 0.2 GO:0042494 detection of bacterial lipoprotein(GO:0042494)
0.1 0.5 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.1 0.3 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.1 0.5 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.1 0.3 GO:0051661 maintenance of centrosome location(GO:0051661)
0.1 1.6 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.1 0.6 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 1.1 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.3 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.3 GO:0071681 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0 1.2 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.5 GO:0002775 antimicrobial peptide production(GO:0002775) antibacterial peptide production(GO:0002778)
0.0 0.5 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.0 0.2 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.1 GO:0050894 determination of affect(GO:0050894)
0.0 0.2 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.4 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 2.9 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 1.5 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.1 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.2 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.0 0.2 GO:0048733 sebaceous gland development(GO:0048733)
0.0 1.3 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.7 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.2 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 0.7 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.2 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.0 0.2 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.9 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 1.3 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.3 GO:0097167 circadian regulation of translation(GO:0097167)
0.0 0.4 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.0 0.1 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.0 0.2 GO:0006983 ER overload response(GO:0006983)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.2 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.0 0.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.3 GO:0036155 positive regulation of triglyceride catabolic process(GO:0010898) acylglycerol acyl-chain remodeling(GO:0036155)
0.0 0.9 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 0.3 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 1.0 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.0 0.6 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.5 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.9 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.0 0.9 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.2 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.6 GO:0050718 positive regulation of interleukin-1 beta secretion(GO:0050718)
0.0 0.1 GO:0072553 terminal button organization(GO:0072553)
0.0 0.2 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.0 1.1 GO:0048008 platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.0 0.4 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 0.4 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.1 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627) negative regulation of T-helper 2 cell differentiation(GO:0045629) negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.8 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0055028 cortical microtubule(GO:0055028)
0.4 2.9 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.2 3.1 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 3.2 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.1 0.4 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.1 0.7 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1 1.1 GO:0097470 ribbon synapse(GO:0097470)
0.1 0.5 GO:0019815 B cell receptor complex(GO:0019815)
0.1 1.5 GO:0071141 SMAD protein complex(GO:0071141)
0.1 0.8 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.2 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 0.2 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.9 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 0.5 GO:0016342 catenin complex(GO:0016342)
0.0 1.4 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 1.1 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.2 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.4 GO:0010369 chromocenter(GO:0010369)
0.0 0.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.5 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 1.4 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 2.0 GO:0045178 basal part of cell(GO:0045178)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.9 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 1.2 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.8 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.5 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.5 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.5 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 6.5 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.2 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.3 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.1 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.3 5.8 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.2 0.6 GO:0032090 Pyrin domain binding(GO:0032090)
0.2 2.8 GO:0051011 microtubule minus-end binding(GO:0051011)
0.2 1.1 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 1.5 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 2.0 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 0.5 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.1 1.4 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1 0.7 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1 1.5 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1 1.0 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.9 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.1 0.8 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.1 0.4 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.1 0.4 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 0.3 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.1 2.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.9 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.2 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.1 1.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 1.2 GO:0030957 Tat protein binding(GO:0030957)
0.1 1.6 GO:0005112 Notch binding(GO:0005112)
0.1 0.9 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 0.3 GO:0004925 prolactin receptor activity(GO:0004925)
0.1 0.2 GO:0004335 galactokinase activity(GO:0004335)
0.0 0.3 GO:0043813 phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.0 0.8 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.1 GO:0031877 somatostatin receptor binding(GO:0031877)
0.0 0.4 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.0 0.9 GO:0017166 vinculin binding(GO:0017166)
0.0 0.3 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.2 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.3 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.8 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.3 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.1 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.0 12.4 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 1.2 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.5 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.5 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.4 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.6 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 1.2 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.7 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.2 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.0 GO:0016936 galactoside binding(GO:0016936)
0.0 0.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.5 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.4 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 3.7 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.2 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.5 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 11.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 1.5 PID ALK2 PATHWAY ALK2 signaling events
0.1 2.5 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 3.7 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 1.3 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 3.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 2.1 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.2 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.6 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.8 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.2 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.6 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.1 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.7 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.8 PID ATM PATHWAY ATM pathway
0.0 0.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.6 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 1.0 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.4 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.2 2.6 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 2.8 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 1.6 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 3.1 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.4 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.3 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.7 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.3 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 1.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.4 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.5 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.1 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.9 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.1 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane