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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for RUNX1_RUNX2

Z-value: 0.86

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Transcription factors associated with RUNX1_RUNX2

Gene Symbol Gene ID Gene Info
ENSG00000159216.14 RUNX family transcription factor 1
ENSG00000124813.16 RUNX family transcription factor 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RUNX1hg19_v2_chr21_-_36260980_362610110.654.3e-04Click!
RUNX2hg19_v2_chr6_+_45296391_452964640.573.2e-03Click!

Activity profile of RUNX1_RUNX2 motif

Sorted Z-values of RUNX1_RUNX2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_131409476 3.85 ENST00000296871.2
colony stimulating factor 2 (granulocyte-macrophage)
chr4_+_89299994 3.23 ENST00000264346.7
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr1_-_173174681 2.90 ENST00000367718.1
tumor necrosis factor (ligand) superfamily, member 4
chr12_+_15125954 2.30 ENST00000266395.2
phosphodiesterase 6H, cGMP-specific, cone, gamma
chr21_-_36421535 2.27 ENST00000416754.1
ENST00000437180.1
ENST00000455571.1
runt-related transcription factor 1
chr21_-_36421626 2.21 ENST00000300305.3
runt-related transcription factor 1
chr4_+_89299885 1.86 ENST00000380265.5
ENST00000273960.3
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr10_+_91152303 1.77 ENST00000371804.3
interferon-induced protein with tetratricopeptide repeats 1
chr20_-_62199427 1.73 ENST00000427522.2
helicase with zinc finger 2, transcriptional coactivator
chr1_+_206643787 1.55 ENST00000367120.3
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr5_+_35856951 1.55 ENST00000303115.3
ENST00000343305.4
ENST00000506850.1
ENST00000511982.1
interleukin 7 receptor
chr11_-_5345582 1.53 ENST00000328813.2
olfactory receptor, family 51, subfamily B, member 2
chr12_+_113344811 1.35 ENST00000551241.1
ENST00000553185.1
ENST00000550689.1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr12_+_113344755 1.33 ENST00000550883.1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr10_+_91092241 1.32 ENST00000371811.4
interferon-induced protein with tetratricopeptide repeats 3
chr11_+_35198118 1.28 ENST00000525211.1
ENST00000526000.1
ENST00000279452.6
ENST00000527889.1
CD44 molecule (Indian blood group)
chr2_+_103035102 1.28 ENST00000264260.2
interleukin 18 receptor accessory protein
chr9_-_130541017 1.28 ENST00000314830.8
SH2 domain containing 3C
chr19_-_15087839 1.27 ENST00000600144.1
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
chr6_+_45296391 1.26 ENST00000371436.6
ENST00000576263.1
runt-related transcription factor 2
chr13_+_50070491 1.23 ENST00000496612.1
ENST00000357596.3
ENST00000485919.1
ENST00000442195.1
PHD finger protein 11
chr2_+_127413704 1.20 ENST00000409836.3
glycophorin C (Gerbich blood group)
chr17_-_29641084 1.15 ENST00000544462.1
ecotropic viral integration site 2B
chr11_+_35198243 1.14 ENST00000528455.1
CD44 molecule (Indian blood group)
chr3_-_127441406 1.09 ENST00000487473.1
ENST00000484451.1
monoglyceride lipase
chr13_-_43566301 1.07 ENST00000398762.3
ENST00000313640.7
ENST00000313624.7
epithelial stromal interaction 1 (breast)
chr16_+_85942594 1.05 ENST00000566369.1
interferon regulatory factor 8
chr3_-_189840223 0.94 ENST00000427335.2
leprecan-like 1
chr8_-_134072593 0.91 ENST00000427060.2
Src-like-adaptor
chr1_+_206643806 0.91 ENST00000537984.1
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr17_-_20370847 0.88 ENST00000423676.3
ENST00000324290.5
lectin, galactoside-binding, soluble, 9B
chr17_+_25958174 0.82 ENST00000313648.6
ENST00000577392.1
ENST00000584661.1
ENST00000413914.2
lectin, galactoside-binding, soluble, 9
chr11_-_128457446 0.78 ENST00000392668.4
v-ets avian erythroblastosis virus E26 oncogene homolog 1
chr10_+_96522361 0.78 ENST00000371321.3
cytochrome P450, family 2, subfamily C, polypeptide 19
chr12_+_113344582 0.77 ENST00000202917.5
ENST00000445409.2
ENST00000452357.2
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr15_-_43910998 0.77 ENST00000450892.2
stereocilin
chr3_-_147124547 0.77 ENST00000491672.1
ENST00000383075.3
Zic family member 4
chr19_+_41768561 0.76 ENST00000599719.1
ENST00000601309.1
heterogeneous nuclear ribonucleoprotein U-like 1
chr16_-_28621353 0.75 ENST00000567512.1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr5_-_76788317 0.73 ENST00000296679.4
WD repeat domain 41
chr10_+_114169299 0.72 ENST00000369410.3
acyl-CoA synthetase long-chain family member 5
chr11_+_1718425 0.72 ENST00000382160.1
keratin associated protein 5-6
chr6_+_31543334 0.70 ENST00000449264.2
tumor necrosis factor
chr11_-_58345569 0.70 ENST00000528954.1
ENST00000528489.1
leupaxin
chr22_+_39378346 0.69 ENST00000407298.3
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
chr12_+_121570631 0.67 ENST00000546057.1
ENST00000377162.2
ENST00000328963.5
ENST00000535250.1
ENST00000541446.1
purinergic receptor P2X, ligand-gated ion channel, 7
chr6_+_26440700 0.66 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
butyrophilin, subfamily 3, member A3
chr12_-_50298000 0.66 ENST00000550635.2
Fas apoptotic inhibitory molecule 2
chr14_-_85996332 0.63 ENST00000380722.1
RP11-497E19.1
chr11_+_71709938 0.63 ENST00000393705.4
ENST00000337131.5
ENST00000531053.1
ENST00000404792.1
interleukin 18 binding protein
chr8_+_54764346 0.63 ENST00000297313.3
ENST00000344277.6
regulator of G-protein signaling 20
chr22_-_30642782 0.63 ENST00000249075.3
leukemia inhibitory factor
chr8_+_31496809 0.62 ENST00000518104.1
ENST00000519301.1
neuregulin 1
chr8_+_104384616 0.62 ENST00000520337.1
collagen triple helix repeat containing 1
chr7_+_154720173 0.61 ENST00000397551.2
PAXIP1 antisense RNA 2
chr17_-_39306054 0.61 ENST00000343246.4
keratin associated protein 4-5
chr15_+_28624878 0.60 ENST00000450328.2
golgin A8 family, member F
chr12_+_129338008 0.60 ENST00000442111.2
ENST00000281703.6
glycosyltransferase 1 domain containing 1
chrX_+_153455547 0.59 ENST00000430054.1
opsin 1 (cone pigments), medium-wave-sensitive
chr6_+_36646435 0.59 ENST00000244741.5
ENST00000405375.1
ENST00000373711.2
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr1_-_209824643 0.59 ENST00000391911.1
ENST00000415782.1
laminin, beta 3
chr11_-_117699413 0.59 ENST00000528014.1
FXYD domain containing ion transport regulator 2
chr6_+_116692102 0.59 ENST00000359564.2
dermatan sulfate epimerase
chr1_-_223536679 0.58 ENST00000608996.1
sushi domain containing 4
chr15_+_84116106 0.58 ENST00000535412.1
ENST00000324537.5
SH3-domain GRB2-like 3
chr6_+_45296048 0.58 ENST00000465038.2
ENST00000352853.5
ENST00000541979.1
ENST00000371438.1
runt-related transcription factor 2
chr1_-_247921982 0.58 ENST00000408896.2
olfactory receptor, family 1, subfamily C, member 1
chr1_-_235098935 0.57 ENST00000423175.1
RP11-443B7.1
chr6_-_11382478 0.57 ENST00000397378.3
ENST00000513989.1
ENST00000508546.1
ENST00000504387.1
neural precursor cell expressed, developmentally down-regulated 9
chr14_-_91720224 0.57 ENST00000238699.3
ENST00000531499.2
G protein-coupled receptor 68
chr17_-_1090599 0.55 ENST00000544583.2
active BCR-related
chr1_+_172422026 0.55 ENST00000367725.4
chromosome 1 open reading frame 105
chr9_+_115913222 0.55 ENST00000259392.3
solute carrier family 31 (copper transporter), member 2
chr2_+_102953608 0.54 ENST00000311734.2
ENST00000409584.1
interleukin 1 receptor-like 1
chr5_-_35938674 0.54 ENST00000397366.1
ENST00000513623.1
ENST00000514524.1
ENST00000397367.2
calcyphosine-like
chr1_-_33336414 0.54 ENST00000373471.3
ENST00000609187.1
fibronectin type III domain containing 5
chr6_+_160327974 0.54 ENST00000252660.4
MAS1 oncogene
chr1_+_172628154 0.54 ENST00000340030.3
ENST00000367721.2
Fas ligand (TNF superfamily, member 6)
chr8_-_119964434 0.54 ENST00000297350.4
tumor necrosis factor receptor superfamily, member 11b
chr6_+_159071015 0.53 ENST00000360448.3
synaptotagmin-like 3
chr6_+_31553978 0.53 ENST00000376096.1
ENST00000376099.1
ENST00000376110.3
leukocyte specific transcript 1
chr7_-_105319536 0.52 ENST00000477775.1
ataxin 7-like 1
chr16_-_75590114 0.52 ENST00000568377.1
ENST00000565067.1
ENST00000258173.6
transmembrane protein 231
chr6_+_31554456 0.52 ENST00000339530.4
leukocyte specific transcript 1
chr10_+_114135004 0.52 ENST00000393081.1
acyl-CoA synthetase long-chain family member 5
chr22_+_25003606 0.52 ENST00000432867.1
gamma-glutamyltransferase 1
chr6_+_31553901 0.51 ENST00000418507.2
ENST00000438075.2
ENST00000376100.3
ENST00000376111.4
leukocyte specific transcript 1
chr3_-_123512688 0.51 ENST00000475616.1
myosin light chain kinase
chr17_+_18380051 0.51 ENST00000581545.1
ENST00000582333.1
ENST00000328114.6
ENST00000412421.2
ENST00000583322.1
ENST00000584941.1
lectin, galactoside-binding, soluble, 9C
chr5_+_67588391 0.50 ENST00000523872.1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr10_+_89420706 0.50 ENST00000427144.2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr2_+_127413677 0.50 ENST00000356887.7
glycophorin C (Gerbich blood group)
chr5_+_125695805 0.49 ENST00000513040.1
GRAM domain containing 3
chr11_-_117698765 0.49 ENST00000532119.1
FXYD domain containing ion transport regulator 2
chr3_+_29322803 0.48 ENST00000396583.3
ENST00000383767.2
RNA binding motif, single stranded interacting protein 3
chr3_-_150920979 0.48 ENST00000309180.5
ENST00000480322.1
G protein-coupled receptor 171
chr1_-_173176452 0.48 ENST00000281834.3
tumor necrosis factor (ligand) superfamily, member 4
chr17_+_74372662 0.48 ENST00000591651.1
ENST00000545180.1
sphingosine kinase 1
chr16_+_1578674 0.48 ENST00000253934.5
transmembrane protein 204
chr2_+_127413481 0.47 ENST00000259254.4
glycophorin C (Gerbich blood group)
chr21_-_37914898 0.47 ENST00000399136.1
claudin 14
chr7_+_75028199 0.47 ENST00000437796.1
tripartite motif containing 73
chr14_-_91710852 0.47 ENST00000535815.1
ENST00000529102.1
G protein-coupled receptor 68
chrX_-_119005735 0.46 ENST00000371442.2
ring finger protein 113A
chr4_-_76928641 0.46 ENST00000264888.5
chemokine (C-X-C motif) ligand 9
chr22_+_21133469 0.46 ENST00000406799.1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr20_+_8112824 0.46 ENST00000378641.3
phospholipase C, beta 1 (phosphoinositide-specific)
chr11_+_61957687 0.45 ENST00000306238.3
secretoglobin, family 1D, member 1
chr4_-_10686373 0.45 ENST00000442825.2
cytokine-dependent hematopoietic cell linker
chr2_+_169659121 0.45 ENST00000397206.2
ENST00000397209.2
ENST00000421711.2
nitric oxide synthase trafficking
chr6_-_114664180 0.45 ENST00000312719.5
heparan sulfate (glucosamine) 3-O-sulfotransferase 5
chr21_-_36421401 0.45 ENST00000486278.2
runt-related transcription factor 1
chr22_+_42665742 0.44 ENST00000332965.3
ENST00000415205.1
ENST00000446578.1
Z83851.3
chr2_+_162272605 0.44 ENST00000389554.3
T-box, brain, 1
chr11_+_71710973 0.44 ENST00000393707.4
interleukin 18 binding protein
chr3_+_190333097 0.44 ENST00000412080.1
interleukin 1 receptor accessory protein
chr3_+_29322933 0.44 ENST00000273139.9
ENST00000383766.2
RNA binding motif, single stranded interacting protein 3
chr12_-_49463753 0.44 ENST00000301068.6
Ras homolog enriched in brain like 1
chr14_+_23352374 0.44 ENST00000267396.4
ENST00000536884.1
RAS (RAD and GEM)-like GTP binding 2
chr4_-_7436671 0.44 ENST00000319098.4
prosaposin-like 1 (gene/pseudogene)
chr20_-_30311703 0.44 ENST00000450273.1
ENST00000456404.1
ENST00000420488.1
ENST00000439267.1
BCL2-like 1
chr8_+_104383728 0.43 ENST00000330295.5
collagen triple helix repeat containing 1
chrX_+_68048803 0.43 ENST00000204961.4
ephrin-B1
chr2_+_37571717 0.43 ENST00000338415.3
ENST00000404976.1
glutaminyl-peptide cyclotransferase
chr11_+_61717842 0.42 ENST00000449131.2
bestrophin 1
chr1_-_201096312 0.42 ENST00000449188.2
achaete-scute family bHLH transcription factor 5
chr1_-_28241024 0.42 ENST00000313433.7
ENST00000444045.1
replication protein A2, 32kDa
chr11_+_71710648 0.42 ENST00000260049.5
interleukin 18 binding protein
chr3_-_33686925 0.42 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
cytoplasmic linker associated protein 2
chr12_+_121647868 0.42 ENST00000359949.7
ENST00000541532.1
ENST00000543171.1
ENST00000538701.1
purinergic receptor P2X, ligand-gated ion channel, 4
chr12_+_57828521 0.42 ENST00000309668.2
inhibin, beta C
chr3_+_29323043 0.42 ENST00000452462.1
ENST00000456853.1
RNA binding motif, single stranded interacting protein 3
chr19_-_2151523 0.42 ENST00000350812.6
ENST00000355272.6
ENST00000356926.4
ENST00000345016.5
adaptor-related protein complex 3, delta 1 subunit
chr1_+_167691185 0.42 ENST00000359523.2
myelin protein zero-like 1
chr4_+_184020398 0.42 ENST00000403733.3
ENST00000378925.3
WW and C2 domain containing 2
chr10_-_24770632 0.41 ENST00000596413.1
AL353583.1
chr7_-_75401513 0.41 ENST00000005180.4
chemokine (C-C motif) ligand 26
chr11_-_5173599 0.41 ENST00000328942.1
olfactory receptor, family 52, subfamily A, member 1
chr20_+_61299155 0.41 ENST00000451793.1
solute carrier organic anion transporter family, member 4A1
chr9_+_126131131 0.41 ENST00000373629.2
crumbs homolog 2 (Drosophila)
chr15_+_89631647 0.40 ENST00000569550.1
ENST00000565066.1
ENST00000565973.1
abhydrolase domain containing 2
chr6_+_26365443 0.40 ENST00000527422.1
ENST00000356386.2
ENST00000396934.3
ENST00000377708.2
ENST00000396948.1
ENST00000508906.2
butyrophilin, subfamily 3, member A2
chr19_-_47291843 0.40 ENST00000542575.2
solute carrier family 1 (neutral amino acid transporter), member 5
chr7_-_115670792 0.40 ENST00000265440.7
ENST00000393485.1
transcription factor EC
chr17_+_56232494 0.40 ENST00000268912.5
olfactory receptor, family 4, subfamily D, member 1
chr16_-_28608364 0.40 ENST00000533150.1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr2_-_216878305 0.40 ENST00000263268.6
melanoregulin
chr17_+_32582293 0.40 ENST00000580907.1
ENST00000225831.4
chemokine (C-C motif) ligand 2
chr1_-_39395165 0.40 ENST00000372985.3
rhomboid, veinlet-like 2 (Drosophila)
chr16_+_30387141 0.40 ENST00000566955.1
myosin light chain, phosphorylatable, fast skeletal muscle
chr11_-_58343319 0.39 ENST00000395074.2
leupaxin
chr12_+_121647962 0.39 ENST00000542067.1
purinergic receptor P2X, ligand-gated ion channel, 4
chr19_+_17982747 0.39 ENST00000222248.3
solute carrier family 5 (sodium/iodide cotransporter), member 5
chr17_+_13972807 0.39 ENST00000429152.2
ENST00000261643.3
ENST00000536205.1
ENST00000537334.1
cytochrome c oxidase assembly homolog 10 (yeast)
chr19_-_6720686 0.39 ENST00000245907.6
complement component 3
chr15_+_67418047 0.39 ENST00000540846.2
SMAD family member 3
chr2_+_202937972 0.39 ENST00000541917.1
ENST00000295844.3
uncharacterized protein KIAA2012
chr16_+_30034655 0.39 ENST00000300575.2
chromosome 16 open reading frame 92
chr17_-_39280419 0.39 ENST00000394014.1
keratin associated protein 4-12
chr11_+_61717279 0.38 ENST00000378043.4
bestrophin 1
chr7_-_115670804 0.38 ENST00000320239.7
transcription factor EC
chrX_-_115594160 0.38 ENST00000371894.4
cancer/testis antigen 83
chr16_-_67867749 0.38 ENST00000566758.1
ENST00000445712.2
ENST00000219172.3
ENST00000564817.1
centromere protein T
chr15_+_67420441 0.38 ENST00000558894.1
SMAD family member 3
chr2_-_229046361 0.38 ENST00000392056.3
SPHK1 interactor, AKAP domain containing
chr11_+_61717336 0.38 ENST00000378042.3
bestrophin 1
chr6_+_24126350 0.38 ENST00000378491.4
ENST00000378478.1
ENST00000378477.2
neurensin 1
chr2_+_37571845 0.38 ENST00000537448.1
glutaminyl-peptide cyclotransferase
chr6_+_31683117 0.38 ENST00000375825.3
ENST00000375824.1
lymphocyte antigen 6 complex, locus G6D
chr2_+_32853093 0.38 ENST00000448773.1
ENST00000317907.4
tetratricopeptide repeat domain 27
chrX_+_150869023 0.37 ENST00000448324.1
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chr15_+_84115868 0.37 ENST00000427482.2
SH3-domain GRB2-like 3
chr19_-_47975417 0.36 ENST00000236877.6
solute carrier family 8 (sodium/calcium exchanger), member 2
chr1_+_203734296 0.36 ENST00000442561.2
ENST00000367217.5
lymphocyte transmembrane adaptor 1
chrX_-_77914825 0.36 ENST00000321110.1
zinc finger, CCHC domain containing 5
chr12_-_112819896 0.36 ENST00000377560.5
ENST00000430131.2
ENST00000550722.1
ENST00000550724.1
HECT domain containing E3 ubiquitin protein ligase 4
chr11_-_108464465 0.36 ENST00000525344.1
exophilin 5
chr7_-_102715263 0.36 ENST00000379305.3
F-box and leucine-rich repeat protein 13
chr6_+_31895467 0.36 ENST00000556679.1
ENST00000456570.1
complement factor B
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr1_-_45308616 0.35 ENST00000447098.2
ENST00000372192.3
patched 2
chr9_+_103189536 0.35 ENST00000374885.1
Myb/SANT-like DNA-binding domain containing 3
chr7_-_102715172 0.35 ENST00000456695.1
ENST00000455112.2
ENST00000440067.1
F-box and leucine-rich repeat protein 13
chr1_-_28241226 0.35 ENST00000373912.3
ENST00000373909.3
replication protein A2, 32kDa
chr5_-_76788024 0.35 ENST00000515253.1
ENST00000414719.2
ENST00000507654.1
ENST00000514559.1
ENST00000511791.1
WD repeat domain 41
chr17_-_69198295 0.35 ENST00000569074.1
cancer susceptibility candidate 17 (non-protein coding)
chr1_+_17866290 0.35 ENST00000361221.3
ENST00000452522.1
ENST00000434513.1
Rho guanine nucleotide exchange factor (GEF) 10-like
chr12_+_20968608 0.35 ENST00000381541.3
ENST00000540229.1
ENST00000553473.1
ENST00000554957.1
Putative solute carrier organic anion transporter family member 1B7; Uncharacterized protein
solute carrier organic anion transporter family, member 1B3
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr5_+_172386517 0.34 ENST00000519522.1
ribosomal protein L26-like 1
chr7_+_65670186 0.34 ENST00000304842.5
ENST00000442120.1
tyrosylprotein sulfotransferase 1
chr22_+_36044411 0.34 ENST00000409652.4
apolipoprotein L, 6
chr22_+_21996549 0.34 ENST00000248958.4
stromal cell-derived factor 2-like 1
chr2_-_217559517 0.34 ENST00000449583.1
insulin-like growth factor binding protein 5
chr19_-_47249679 0.33 ENST00000263280.6
striatin, calmodulin binding protein 4
chr10_+_115438920 0.33 ENST00000429617.1
ENST00000369331.4
caspase 7, apoptosis-related cysteine peptidase
chr1_+_196743912 0.33 ENST00000367425.4
complement factor H-related 3
chr4_+_159236462 0.33 ENST00000460056.2
relaxin/insulin-like family peptide receptor 1
chr1_-_157014865 0.33 ENST00000361409.2
Rho guanine nucleotide exchange factor (GEF) 11
chr14_+_93799556 0.33 ENST00000256339.4
unc-79 homolog (C. elegans)
chrX_-_15332665 0.33 ENST00000537676.1
ENST00000344384.4
ankyrin repeat and SOCS box containing 11
chr9_-_130517522 0.33 ENST00000373274.3
ENST00000420366.1
SH2 domain containing 3C

Network of associatons between targets according to the STRING database.

First level regulatory network of RUNX1_RUNX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.8 3.8 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.6 1.8 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.3 1.0 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.3 5.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.3 2.4 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.3 0.8 GO:2001190 natural killer cell tolerance induction(GO:0002519) positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.3 0.8 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.2 0.7 GO:0043132 NAD transport(GO:0043132)
0.2 0.6 GO:0080154 regulation of fertilization(GO:0080154)
0.2 1.8 GO:0002051 osteoblast fate commitment(GO:0002051)
0.2 0.5 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.2 1.3 GO:0070778 L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712)
0.2 0.5 GO:0042489 negative regulation of odontogenesis of dentin-containing tooth(GO:0042489)
0.2 0.5 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.2 1.0 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.2 0.5 GO:1901899 positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.2 0.5 GO:0046521 sphingoid catabolic process(GO:0046521)
0.2 0.6 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.2 1.1 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.2 0.8 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.2 0.5 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.1 0.4 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.1 1.0 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.1 0.3 GO:0002215 defense response to nematode(GO:0002215)
0.1 0.6 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.1 0.3 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.1 1.0 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.1 0.4 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
0.1 0.4 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.1 0.3 GO:0043396 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
0.1 0.5 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 0.7 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.4 GO:0002894 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.1 0.5 GO:0000103 sulfate assimilation(GO:0000103)
0.1 0.4 GO:1905071 occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.1 0.5 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 0.1 GO:1905154 negative regulation of membrane invagination(GO:1905154)
0.1 1.0 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 1.4 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1 1.1 GO:0006477 protein sulfation(GO:0006477)
0.1 0.3 GO:2000870 regulation of progesterone secretion(GO:2000870)
0.1 0.4 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.1 0.4 GO:0019046 release from viral latency(GO:0019046)
0.1 0.4 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 0.4 GO:0001189 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.1 0.4 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.3 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.1 0.3 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.1 0.3 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.1 0.7 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.1 1.3 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.1 0.4 GO:1903803 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.1 0.3 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.1 0.5 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.8 GO:0030578 PML body organization(GO:0030578)
0.1 0.4 GO:1904616 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.1 0.3 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1 0.3 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.1 1.5 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 0.3 GO:0002325 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.1 1.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 0.5 GO:2001274 negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.1 0.3 GO:1904808 regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.1 0.6 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 0.2 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.1 0.3 GO:0060722 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.1 0.1 GO:0070352 positive regulation of white fat cell proliferation(GO:0070352)
0.1 0.9 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.2 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.1 0.5 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 0.7 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.1 0.2 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 0.2 GO:0007518 myoblast fate determination(GO:0007518)
0.1 1.2 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.1 0.2 GO:0006500 N-terminal protein palmitoylation(GO:0006500)
0.1 1.0 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 0.1 GO:0097325 melanocyte proliferation(GO:0097325)
0.1 0.4 GO:0021764 amygdala development(GO:0021764)
0.1 0.4 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.1 0.2 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.1 0.1 GO:0051832 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1 1.4 GO:0051923 sulfation(GO:0051923)
0.1 0.4 GO:0014028 notochord formation(GO:0014028)
0.1 0.3 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.1 0.5 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.1 0.7 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.1 0.2 GO:0001694 histamine biosynthetic process(GO:0001694)
0.1 0.1 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.1 2.7 GO:0035456 response to interferon-beta(GO:0035456)
0.1 0.6 GO:0090400 stress-induced premature senescence(GO:0090400)
0.1 0.3 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.3 GO:0015783 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.1 0.1 GO:0002774 Fc receptor mediated inhibitory signaling pathway(GO:0002774)
0.1 0.2 GO:1904636 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.1 0.2 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1 0.2 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.1 0.2 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.1 0.2 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.1 0.1 GO:0036215 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.1 0.2 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.1 0.2 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.1 0.2 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.1 0.8 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1 0.2 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.1 0.2 GO:0060381 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381)
0.1 0.3 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.1 1.5 GO:1900116 extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 0.5 GO:0043144 snoRNA processing(GO:0043144)
0.1 0.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.2 GO:0035455 response to interferon-alpha(GO:0035455)
0.1 2.1 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.1 0.1 GO:0002885 regulation of type I hypersensitivity(GO:0001810) positive regulation of type I hypersensitivity(GO:0001812) positive regulation of hypersensitivity(GO:0002885) type I hypersensitivity(GO:0016068)
0.1 0.1 GO:0014839 myoblast migration involved in skeletal muscle regeneration(GO:0014839)
0.1 0.3 GO:0098502 DNA dephosphorylation(GO:0098502)
0.0 0.1 GO:0060166 olfactory pit development(GO:0060166)
0.0 4.5 GO:0071357 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.3 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.2 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.5 GO:1903943 negative regulation of myoblast fusion(GO:1901740) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 1.1 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.2 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.0 1.4 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.5 GO:0010454 negative regulation of cell fate commitment(GO:0010454)
0.0 0.7 GO:0010529 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.0 0.3 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.2 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.3 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.0 0.4 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.2 GO:2001178 mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
0.0 0.1 GO:0044278 cell wall disruption in other organism(GO:0044278)
0.0 0.4 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.2 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.1 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.0 0.4 GO:0009957 epidermal cell fate specification(GO:0009957)
0.0 0.2 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.2 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.2 GO:1904640 response to methionine(GO:1904640)
0.0 0.1 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.0 0.3 GO:0015705 iodide transport(GO:0015705)
0.0 0.4 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.0 0.3 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.0 0.2 GO:0003383 apical constriction(GO:0003383)
0.0 0.3 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.1 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.0 0.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:1904106 protein localization to microvillus(GO:1904106)
0.0 0.1 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.0 0.2 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.3 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 2.7 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.7 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.2 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.2 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.4 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.2 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.1 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.1 GO:0006050 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.0 0.5 GO:0014820 tonic smooth muscle contraction(GO:0014820)
0.0 0.0 GO:0060313 negative regulation of blood vessel remodeling(GO:0060313)
0.0 0.5 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.2 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.1 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.3 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.2 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.0 0.2 GO:0035900 response to isolation stress(GO:0035900)
0.0 0.3 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.2 GO:0014738 regulation of muscle hyperplasia(GO:0014738)
0.0 0.2 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.2 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986) response to heparin(GO:0071503)
0.0 0.1 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.0 0.4 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.2 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.3 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 1.0 GO:0098926 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 0.1 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.0 GO:1902227 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.0 0.2 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.1 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.6 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.4 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.3 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.2 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.1 GO:0003160 endocardium morphogenesis(GO:0003160) endocardium formation(GO:0060214)
0.0 0.2 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.1 GO:0060437 lung growth(GO:0060437)
0.0 3.1 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.0 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.1 GO:1903517 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.0 0.1 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0 0.9 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.0 0.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.1 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.0 0.4 GO:0060742 epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.0 0.1 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.0 0.3 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.3 GO:0090394 negative regulation of excitatory postsynaptic potential(GO:0090394) regulation of retina development in camera-type eye(GO:1902866)
0.0 0.2 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:0002863 positive regulation of inflammatory response to antigenic stimulus(GO:0002863)
0.0 0.1 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.0 0.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.3 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.0 0.3 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.2 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.5 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.0 0.2 GO:0048318 axial mesoderm development(GO:0048318)
0.0 0.1 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.1 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.4 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.3 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
0.0 0.1 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.0 0.1 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.5 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.3 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.1 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.1 GO:0071104 response to interleukin-9(GO:0071104)
0.0 0.1 GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.0 0.1 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.0 0.2 GO:0032226 positive regulation of synaptic transmission, dopaminergic(GO:0032226)
0.0 0.1 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.4 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:0007538 primary sex determination(GO:0007538)
0.0 0.1 GO:0072218 ascending thin limb development(GO:0072021) metanephric ascending thin limb development(GO:0072218)
0.0 1.0 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.2 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.2 GO:0045651 positive regulation of macrophage differentiation(GO:0045651)
0.0 0.1 GO:0032571 response to vitamin K(GO:0032571)
0.0 0.4 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.3 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.0 0.1 GO:0051884 regulation of anagen(GO:0051884)
0.0 0.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.1 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.1 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.3 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.3 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.0 0.1 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.4 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.1 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0 0.1 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.0 0.4 GO:0036315 cellular response to sterol(GO:0036315)
0.0 0.2 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.0 0.1 GO:0061760 antifungal innate immune response(GO:0061760)
0.0 0.0 GO:0042495 detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.0 0.1 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.4 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.2 GO:0060699 regulation of endoribonuclease activity(GO:0060699) regulation of ribonuclease activity(GO:0060700)
0.0 0.5 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.1 GO:0044209 AMP salvage(GO:0044209)
0.0 0.1 GO:0010269 response to selenium ion(GO:0010269)
0.0 0.1 GO:0090346 nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210) cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
0.0 0.5 GO:0048305 immunoglobulin secretion(GO:0048305)
0.0 0.0 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.0 0.3 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.2 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.1 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.3 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 0.2 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.2 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0 0.1 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.1 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.2 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.0 0.2 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.0 0.6 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.0 0.3 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 0.2 GO:0033033 negative regulation of myeloid cell apoptotic process(GO:0033033)
0.0 0.1 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.0 0.1 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.1 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.0 0.3 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 0.3 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.0 0.0 GO:0016999 antibiotic metabolic process(GO:0016999)
0.0 0.2 GO:0032439 endosome localization(GO:0032439)
0.0 0.1 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.0 0.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.1 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.1 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.0 0.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0097476 spinal cord motor neuron migration(GO:0097476)
0.0 0.1 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.1 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.0 0.0 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.1 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0 0.2 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.2 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.0 0.1 GO:0071105 response to interleukin-11(GO:0071105)
0.0 0.1 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 0.1 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.2 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.0 GO:0071317 cellular response to morphine(GO:0071315) cellular response to isoquinoline alkaloid(GO:0071317)
0.0 0.1 GO:0046618 drug export(GO:0046618)
0.0 0.0 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.1 GO:0070836 caveola assembly(GO:0070836)
0.0 0.0 GO:0046684 response to pyrethroid(GO:0046684)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.7 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 0.1 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.2 GO:0015816 glycine transport(GO:0015816)
0.0 0.1 GO:0090034 regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.0 0.1 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.0 0.1 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.5 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.6 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.0 0.3 GO:0050974 detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.0 0.2 GO:0072537 fibroblast activation(GO:0072537)
0.0 0.2 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.1 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.1 GO:0097106 postsynaptic density organization(GO:0097106)
0.0 0.1 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.1 GO:0071332 cellular response to fructose stimulus(GO:0071332)
0.0 0.1 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.0 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.0 0.1 GO:0072199 ureter smooth muscle development(GO:0072191) ureter smooth muscle cell differentiation(GO:0072193) mesenchymal cell proliferation involved in ureter development(GO:0072198) regulation of mesenchymal cell proliferation involved in ureter development(GO:0072199) positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.0 0.1 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.0 GO:0019303 D-ribose catabolic process(GO:0019303)
0.0 0.1 GO:0070474 positive regulation of uterine smooth muscle contraction(GO:0070474)
0.0 0.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.1 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.1 GO:0002765 immune response-inhibiting signal transduction(GO:0002765)
0.0 0.1 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.1 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 4.0 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 0.2 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.8 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.0 GO:1903463 regulation of mitotic cell cycle DNA replication(GO:1903463) negative regulation of mitotic cell cycle DNA replication(GO:1903464)
0.0 0.3 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.1 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.3 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.2 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.1 GO:0099551 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.0 0.2 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 0.2 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 0.0 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.1 GO:0060174 limb bud formation(GO:0060174)
0.0 0.1 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.0 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.2 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.1 GO:0006983 ER overload response(GO:0006983)
0.0 0.1 GO:2001204 regulation of osteoclast development(GO:2001204)
0.0 0.0 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.2 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.0 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.0 0.2 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.0 GO:0034238 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241)
0.0 0.0 GO:2000566 CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.0 0.1 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.1 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.0 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.0 0.0 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.0 0.1 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.0 0.0 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.0 GO:0097104 postsynaptic membrane assembly(GO:0097104)
0.0 0.2 GO:0006071 glycerol metabolic process(GO:0006071)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.4 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.2 0.6 GO:0070557 PCNA-p21 complex(GO:0070557)
0.2 0.5 GO:0005668 RNA polymerase transcription factor SL1 complex(GO:0005668)
0.1 0.6 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 0.5 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 0.4 GO:0043159 acrosomal matrix(GO:0043159)
0.1 1.4 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 0.8 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 1.0 GO:0060091 kinocilium(GO:0060091)
0.1 0.7 GO:0031415 NatA complex(GO:0031415)
0.1 1.0 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 0.6 GO:0005610 laminin-5 complex(GO:0005610)
0.1 1.0 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.3 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.1 0.3 GO:0034457 Mpp10 complex(GO:0034457)
0.1 0.2 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.4 GO:0019815 B cell receptor complex(GO:0019815)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.1 1.4 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 0.2 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1 1.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.2 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.6 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.2 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.2 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.6 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.4 GO:0061617 MICOS complex(GO:0061617)
0.0 0.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.2 GO:1990037 Lewy body core(GO:1990037)
0.0 0.2 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.5 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 1.0 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.3 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0 0.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.6 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.2 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:1990423 RZZ complex(GO:1990423)
0.0 0.2 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.2 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.3 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.1 GO:0002081 outer acrosomal membrane(GO:0002081)
0.0 0.1 GO:0044393 microspike(GO:0044393)
0.0 0.1 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.4 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 0.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.2 GO:0061574 ASAP complex(GO:0061574)
0.0 0.3 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.5 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.5 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.3 GO:0070187 telosome(GO:0070187)
0.0 0.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.1 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.3 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 3.0 GO:0016605 PML body(GO:0016605)
0.0 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.0 1.1 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.5 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.7 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.1 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.1 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.2 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.1 GO:0044754 autolysosome(GO:0044754)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.1 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.2 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.1 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 2.2 GO:0030863 cortical cytoskeleton(GO:0030863)
0.0 0.4 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.4 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.1 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.0 GO:0097059 CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059)
0.0 0.1 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.5 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.0 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.2 GO:0032433 filopodium tip(GO:0032433)
0.0 0.0 GO:0097447 dendritic tree(GO:0097447)
0.0 0.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.3 GO:0042588 zymogen granule(GO:0042588)
0.0 0.4 GO:0005771 multivesicular body(GO:0005771)
0.0 0.1 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:0030314 junctional membrane complex(GO:0030314)
0.0 1.3 GO:0018995 host(GO:0018995) host cell(GO:0043657)
0.0 1.2 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.0 0.4 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.1 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.2 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.5 1.6 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.5 1.5 GO:0042007 interleukin-18 binding(GO:0042007)
0.3 3.5 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.3 0.8 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.2 1.4 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.2 0.6 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.2 0.5 GO:0002113 interleukin-33 binding(GO:0002113)
0.2 1.3 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.2 0.5 GO:0004020 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.2 0.8 GO:0048030 disaccharide binding(GO:0048030)
0.2 0.8 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.4 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.1 0.4 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.1 0.4 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.1 0.7 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.1 1.5 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.4 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.4 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.1 0.6 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 0.3 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 0.3 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 0.8 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.1 0.4 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.1 0.5 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 0.7 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.1 0.4 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 0.4 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 1.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 4.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.5 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.3 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.1 0.3 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.3 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 0.5 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.1 0.4 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.1 0.6 GO:0001727 lipid kinase activity(GO:0001727)
0.1 1.6 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 0.5 GO:0004882 androgen receptor activity(GO:0004882)
0.1 1.0 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.4 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.1 2.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.4 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.1 2.3 GO:0030553 cGMP binding(GO:0030553)
0.1 1.1 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.1 0.3 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 0.3 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
0.1 0.4 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.1 0.2 GO:0004040 amidase activity(GO:0004040)
0.1 0.7 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 0.4 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 0.9 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.1 0.3 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 0.4 GO:0042835 BRE binding(GO:0042835)
0.1 0.3 GO:0005457 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.1 0.4 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 1.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.2 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 1.2 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.1 0.4 GO:0005119 smoothened binding(GO:0005119)
0.1 0.2 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.1 0.2 GO:0047661 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.1 0.4 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.2 GO:0004803 transposase activity(GO:0004803)
0.1 0.3 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.1 0.3 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.1 0.2 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345) 6-phosphogluconolactonase activity(GO:0017057)
0.1 0.4 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.1 0.3 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.5 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 0.3 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.2 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.2 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.2 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.0 0.3 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.1 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.0 0.1 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 0.3 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.6 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.3 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.7 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.4 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.1 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.0 1.0 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.4 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.3 GO:0004515 nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.2 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.0 0.4 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.5 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.1 GO:0098808 mRNA cap binding(GO:0098808)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.5 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.2 GO:0035473 lipase binding(GO:0035473)
0.0 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.6 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0070984 SET domain binding(GO:0070984)
0.0 0.4 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 1.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.5 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.1 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 3.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.1 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
0.0 0.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.3 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.2 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.0 0.1 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.5 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 1.0 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.4 GO:0004568 chitinase activity(GO:0004568)
0.0 0.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 0.1 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.0 0.1 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.0 0.7 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.3 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.8 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) DNA/RNA helicase activity(GO:0033677)
0.0 0.3 GO:0032190 acrosin binding(GO:0032190)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.0 0.7 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0 0.1 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.0 0.2 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.2 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.6 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 1.2 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 1.3 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.5 GO:0001163 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 1.0 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0031716 calcitonin receptor binding(GO:0031716)
0.0 0.3 GO:1903136 cuprous ion binding(GO:1903136)
0.0 0.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.1 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0047726 iron-cytochrome-c reductase activity(GO:0047726)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.3 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.8 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 3.5 GO:0070851 growth factor receptor binding(GO:0070851)
0.0 0.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.1 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.2 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.1 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.3 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.1 GO:0003947 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity(GO:0003947)
0.0 0.3 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.1 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 0.3 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.1 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 1.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.1 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.0 0.5 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0 5.7 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.0 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.6 GO:0001848 complement binding(GO:0001848)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 0.2 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.0 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.1 GO:0004630 phospholipase D activity(GO:0004630) N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)
0.0 0.1 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.1 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.2 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0005497 androgen binding(GO:0005497)
0.0 0.4 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.1 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.2 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.4 GO:0005521 lamin binding(GO:0005521)
0.0 3.3 GO:0001047 core promoter binding(GO:0001047)
0.0 0.2 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.1 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.1 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 1.5 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.2 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.0 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.0 0.1 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.1 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0 0.4 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.2 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.3 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.3 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.1 GO:0031014 troponin T binding(GO:0031014)
0.0 0.2 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.8 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.0 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.1 GO:0023029 MHC class Ib protein binding(GO:0023029)
0.0 0.3 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.7 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 6.1 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.1 0.8 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 2.3 PID CONE PATHWAY Visual signal transduction: Cones
0.1 4.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.0 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 1.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 2.1 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 1.4 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.3 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 1.1 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 0.3 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.9 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 2.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.9 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.1 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 1.8 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 2.3 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.5 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.4 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.1 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.1 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.5 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.2 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.2 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.7 PID ATR PATHWAY ATR signaling pathway
0.0 0.4 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway
0.0 0.0 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.4 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.1 PID IL5 PATHWAY IL5-mediated signaling events
0.0 4.4 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.3 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.3 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.5 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.4 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.1 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 0.1 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 2.1 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.1 4.3 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 7.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 1.5 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 0.9 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 0.9 REACTOME OPSINS Genes involved in Opsins
0.1 1.9 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 0.8 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 1.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 0.9 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 1.1 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 1.1 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.4 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.9 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.4 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 1.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.2 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.6 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 2.9 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.6 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 1.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 2.0 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.3 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.6 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.4 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.1 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.6 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.7 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.3 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 1.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.3 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.5 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.2 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.2 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.6 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.0 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.2 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL